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ID:1043836
User:217.33.149.234
Article:Effects of long-term contact lens wear on the cornea
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Two explanations have been proposed for contact lens-induced stromal thinning. It is thought that contact lens-induced edema may inhibit stroma tissue synthesis.<ref name="Effects of long-term extended contact lens wear on the human cornea." /> Alternatively, contact lens-induced hypoxia may trigger a lactic acid buildup that leads to the erosion of stromal tissue.<ref name="Effects of long-term extended contact lens wear on the human cornea." /> The mechanism behind contact lens-induced polymegathism is unknown, though it is also thought to be a byproduct of corneal edema and epithelial hypoxia.<ref name="Effects of long-term extended contact lens wear on the human cornea." />
 
Two explanations have been proposed for contact lens-induced stromal thinning. It is thought that contact lens-induced edema may inhibit stroma tissue synthesis.<ref name="Effects of long-term extended contact lens wear on the human cornea." /> Alternatively, contact lens-induced hypoxia may trigger a lactic acid buildup that leads to the erosion of stromal tissue.<ref name="Effects of long-term extended contact lens wear on the human cornea." /> The mechanism behind contact lens-induced polymegathism is unknown, though it is also thought to be a byproduct of corneal edema and epithelial hypoxia.<ref name="Effects of long-term extended contact lens wear on the human cornea." />
   
It is thought that constant adhesion of contact lenses to the cornea may lead to adaptation to mechanical stimuli, thus decreasing corneal sensitivity to tactile stimuli. A proposed explanation for the reduced sensitivity is the induced quiescence of free nerve endings following long term corneal exposure to contact lenses.<ref name="Effect of Long-term Wear of Hard Contact Lenses on Corneal Sensitivity" />
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It is thought that constant adhesion of contact lenses to the cornea may lead to adaptation to mechanical stimuli, thus decreasing corneal sensitivity to tactile stimuli. A proposed explanation for the reduced sensitivity is the induced quiescence of free nerve endings following long term corneal exposure to contact lenses.<ref name="Effect of Long-term Wear of Hard Contact Lenses on Corneal Sensitivity" />JOKE
   
 
== See also ==
 
== See also ==
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