Search All

Articles

1. Molecular diagnostics in medical mycology 2018

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9RAEB9sRfClWBWN1iOCb5Im-3m7UAr28KgPhXtQEF-W_Yp34KWlHw_333d2k5w98akQlpBNYJiZ3ZnNzPwG4FMTSNuIQCpc1LLiUeM-SBipmHJBChtSLGn3Zw6IsRYmJ-17tzru_qyPu9Uy51ZerX095onVi4uZpOi0NLreg70p4w-O6Hn7ZRpPLXwokGmYqm943g4aoio0kEJWqV0NS9pIc5e3v_Yow_b_z9f8N2XygQ2av4CDwXksv_REHsKT2L2EZ307yc0raC7GXrdl6DPoEgZzuerKdR-OKU-Wp-tNxqnenNTL09fwY_71--y8GjoiVJ5reVv5wGgQPHDatppHFUnQiateUGlFI1UUVMdUda9ba30gwlKCF_eOa-Q9ewsl1w7ttvRhmpDvEyCgQiNvG--sY4TYAj6PDDFXPeKFyZFqpkzPSYOcNJmTRhRwlni2fTOhVecHl9e_zSAzE7yXwkUtLFdcUK9CG2VoPHUyOtxxCzgaOW6GJXRjkGqFvpImrICP22lU_hTRsF28vMvvaCXQayMFvOkFtKVkFHAB0x3R7ZC6O4P6lgG2B_169-gv38NzmtQtpb2wI9i_vb6LH2A_VWVMUGd_TvN4NoGn57Nv81-TlHG6wHEh0j1q8z1eXfKi

   Wickes, Brian L; Wiederhold, Nathan P

   Nature Communications, Vol. 9, Issue 1, p. 5135.

   Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal ide... Read more

   Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today's clinical microbiology laboratories. Read less

   Journal Article  |  Full Text Online

2. Disaster mycology 2023

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV05T8MwFH6iHRAL4hINR9UBiSnN4cSHVFWC0gqGSgwwR7YT00q0VKUM_fc8201FVpYMuf35-N6z3_sMcBeXiYnzMgmxU9MwqwSOgwlJQsJVSXNZ2rWk5mQO0DoXxgXtazXvLz8X_eV85mIrVwsd1XFi0et0ZG0CwZI8akGLkaz20f34m6EN7gMX0TFCemJeqpGxOI98SjuWvk9FZrfQIWhcIiWmDVZy4v1_GKkZLenjJB39TE7geGc39h78_53CQbU8g8PpbmX8HDpP829pRQ96g9lwsXVa1NtBNBtewPtk_DZ6Dne7HoSasHQTSoEWlMFuoQxBDzJmkhKZ09LwlMXKaOxhlAtj0FczWhmO9JLGVlbOsMpQw0kHeplQyM1Ul8yq21vRP45ELmOtpCJJIgO4r4tbrLyqRYHegMWo2GNUWIwCeLRo7O-yatTuxNf6o9jVScGZJEpUspJSZknKhFaqRFuQZZqYitMALj2E-9fUuAfAG-A2vtO8go3BqV_XlX_1_0ev4cjuGu-nhm-gvVn_VLfQtkkTXeeU43H8Mum6dvUL2onPXQ

   Smith, Daniel F Q; Casadevall, Arturo

   Biomedica : Revista Del Instituto Nacional De Salud, Vol. 43, Issue Sp. 1, pp. 267 - 277.

   Natural and human-made disasters have long played a role in shaping the environment and microbial communities, also affecting non-microbial life on Earth. Disaster microbiology is a new concept bas... Read more

   Natural and human-made disasters have long played a role in shaping the environment and microbial communities, also affecting non-microbial life on Earth. Disaster microbiology is a new concept based on the notion that a disaster changes the environment causing adaptation or alteration of microbial populations -growth, death, transportation to a new area, development traits, or resistance- that can have downstream effects on the affected ecosystem. Such downstream effects include blooms of microbial populations and the ability to colonize a new niche or host, cause disease, or survive in former extreme conditions. Throughout history, fungal populations have been affected by disasters. There are prehistoric archeological records of fungal blooms after asteroid impacts and fungi implicated in the fall of the dinosaurs. In recent times, drought and dust storms have caused disturbance of soil fungi, and hurricanes have induced the growth of molds on wet surfaces, resulting in an increased incidence of fungal disease. Probably, the anticipated increase in extreme heat would force fungi adaptation to survive at high temperatures, like those in the human body, and thus be able to infect mammals. This may lead to a drastic rise of new fungal diseases in humans. Read less

   Journal Article  |  Full Text Online

3. The current state of laboratory mycology in Asia/Pacific: A survey from the European... 2023

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1ta9swED62lo192Us3tuyNK4yyQt1YVizbIxRMaUkZGYV1nz3ZUlYX6oy4Gfhv7hdNJ8ltChnb2Ech-SSjR9JJd_ccwLtQsVkYKxaYRS2Ckc7MPsg4C3haKhFLRbak2485LiisXWPCt65Y9YXppabw-W_7lO57n3jPWHoXNs35I8yVazM_-Tj5dG09iLlNThyau0WQxkl2H7b_KOx359JavZP78-f4EXztR27dTijZwar__dByHlqii57f8V__8jE89Lop5g5MT-CObrbgnstW2W3Bzqmjue728Owmaqvdwx08vSHA7p7CT1ONlSN-QhuxhPMZerjNFx2Ozw8uO9d6PDw_wLrBvK3l0HsIfsAc2-Xih-6Qol_Q6KjYWw3QhigSXSghiuR6UxMJna4KfX90OJ3uomwU3nr2RO-oikZdR2vDsG3ypr5cJ-Xk8ySf7j6DL8dHZ4eTwOeOCCpzoboKUq7iiiU6SVKuFedcZqVWESurkRwpXXJzTzM1EZecUmpVIa9mIjOlRPNSxIq_ABxlpdFwRKUSyhFA1ImpUYdkWJWy5IzJAUQ9ZIrvjhuk6J3mLoqV6SxoOgs3nQMY9-AqvJLjlJfCIOJvPt_uAVmYjYCsO7LR82VbRImIiTwyiQbw3CH1elRcCGKyYy__r_NX8IBKzgXvNWxcLZb6DWwQ2N_6NfgLdBQ03Q

   Salmanton-García, Jon; Au, Wing-Yan; Hoenigl, Martin; Chai, Louis Yi Ann...

   International Journal Of Antimicrobial Agents, Vol. 61, Issue 3, p. 106718.

   •Diagnostic tools in laboratory mycology are in continuous development worldwide, including validation of new techniques.•Economical or geographical factors may play a key role in the incidence and... Read more

   •Diagnostic tools in laboratory mycology are in continuous development worldwide, including validation of new techniques.•Economical or geographical factors may play a key role in the incidence and clinical handling of invasive fungal infections (IFIs).•Efforts to depict the status of the diagnostic capacity for IFIs have been made at a pan-Asia/Pacific level.•IFI diagnostic status and therapeutic capabilities in Asia/Pacific are heterogeneous because of IFI endemicity and burden and economic resources.•Partnerships are required to advance understanding, diagnostics and management of IFI, and to augment fungal surveillance data. Introduction: Invasive fungal infections (IFIs) in Asia/Pacific are a particular threat to patients with malignancies, uncontrolled diabetes mellitus or undiagnosed/untreated human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS). Adequate and early access to diagnostic tools and antifungals is essential for IFI clinical management and patient survival. Methods: Details on institution profile, self-perception on IFI, and access to microscopy, culture, serology, antigen detection, molecular testing, and therapeutic drug monitoring for IFI were collected in a survey. Results: As of June 2022, 235 centres from 40 countries/territories in Asia/Pacific answered the questionnaire. More than half the centres were from six countries: India (25%), China (17%), Thailand (5%), Indonesia, Iran, and Japan (4% each). Candida spp. (93%) and Aspergillus spp. (75%) were considered the most relevant pathogens. Most institutions had access to microscopy (98%) or culture-based approaches (97%). Furthermore, 79% of centres had access to antigen detection, 66% to molecular assays, and 63% to antibody tests. Access to antifungals varied between countries/territories. At least one triazole was available in 93% of the reporting sites (voriconazole [89%] was the most common mould-active azole), whereas 80% had at least one amphotericin B formulation, and 72% had at least one echinocandin. Conclusion: According to the replies provided, the resources available for IFI diagnosis and management vary among Asia/Pacific countries/territories. Economical or geographical factors may play a key role in the incidence and clinical handling of this disease burden. Regional cooperation may be a good strategy to overcome shortcomings. Read less

   Journal Article  |  Full Text Online

See all 2,490,679 article results