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Antibiotics : newer agents, new uses for older agents, and strategies to minimize resistance / [with] Jay B. Varkey.
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2014
Available at Available Online Academic Video Online (USU and USU Eastern) (Call number: Streaming Video)
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Antibiotics [electronic resource] : FDA needs to do more to ensure that drug labels contain up-to-date information : report to congressional committees.
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2012
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Antibiotics [electronic resource] : the wonder drugs.
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1994
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Antibiotics : oft gone astray / Annabel Hecht.
Government Document
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1981
Available at Available Merrill-Cazier Government Documents (Lower Level) (Call number: HE 20.4010/A:AN 8)
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Antibiotics / edited by David Gottlieb and Paul D. Shaw.
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1967
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Antibiotics; origin, nature and properties. [by] Tadeusz Korzybski, Zuzanna Kowszyk-Gindifer [and] Włodzimierz Kuryłowicz. Translated by Edwin Paryski.
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1967
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| Call No. | g gbks UUS MCLIBRARY BARNBOOKS RM267 .K6513 1967 |
| Location | Merrill-Cazier BARN, Books, Circulation Desk (1st Floor) |
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Antibiotics: their chemistry and non-medical uses.
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1959
Available at Available Merrill-Cazier Books (3rd Floor North) (Call number: QR84 .G57)
Antibiotics : a survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants / by H. W. Florey [and others]
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1949 -
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A Quality Improvement Project to Increase Compliance With a Facility Protocol on Surgical Antimicrobial Prophylaxis.
Academic Journal
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Publisher: Wiley Country of Publication: United States NLM ID: 0372403 Publication Model: Print Cited Medium: Internet ISSN: 1878-0369 (Electronic) Linking ISSN: 00012092 NLM ISO Abbreviation: AORN J Subsets: MEDLINE
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Wysocki K;Zedreck Gonzalez JF;Ren D
Academic Journal
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Publisher: Wiley Country of Publication: United States NLM ID: 0372403 Publication Model: Print Cited Medium: Internet ISSN: 1878-0369 (Electronic) Linking ISSN: 00012092 NLM ISO Abbreviation: AORN J Subsets: MEDLINE
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Surgical site infections (SSIs) contribute to negative outcomes for patients and healt...
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A Quality Improvement Project to Increase Compliance With a Facility Protocol on Surgical Antimicrobial Prophylaxis.
Publisher: Wiley Country of Publication: United States NLM ID: 0372403 Publication Model: Print Cited Medium: Internet ISSN: 1878-0369 (Electronic) Linking ISSN: 00012092 NLM ISO Abbreviation: AORN J Subsets: MEDLINE
Surgical site infections (SSIs) contribute to negative outcomes for patients and health care organizations. Compliance with clinical practice guidelines likely can help prevent SSIs. An interdisciplinary team at a regional referral center in Michigan sought to reduce SSIs by improving compliance with the facility's preoperative antibiotic selection, dosing, timing, and redosing protocol. The interventions for the quality improvement project included adding the preprocedural antibiotics and doses to the master OR schedule; holding an education session for all preoperative nurses, intraoperative nurses, and anesthesia professionals; and posting a reference guide in the preoperative and intraoperative areas. Compliance with the facility's protocol for antibiotic selection, dosing, and timing significantly improved. However, SSI rates and compliance with redosing recommendations did not change significantly. The team decided to add the antibiotic order information to the master OR schedule permanently. The team plans to consider providing education sessions on administering preprocedural antibiotics outside the OR.
(© AORN, Inc, 2024.)
(© AORN, Inc, 2024.)
Subject terms:
Humans - Michigan - Anti-Bacterial Agents administration & dosage - Anti-Bacterial Agents therapeutic use - Quality Improvement - Antibiotic Prophylaxis standards - Antibiotic Prophylaxis methods - Antibiotic Prophylaxis statistics & numerical data - Surgical Wound Infection prevention & control - Guideline Adherence statistics & numerical data - Guideline Adherence standardsContent provider:
MEDLINE
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The market for chicken raised without antibiotics, 2012-17 / Elina T. Page [and three others].
Electronic Government Doc
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2021
Available at Online freely available Government Documents (USU and USU Eastern)
Regional antibiotic delivery for sternal wound infection prophylaxis a systematic review and meta-analysis of randomized controlled trials.
Academic Journal
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Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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Kowalewski M;Kołodziejczak MM;Urbanowicz T;De Piero ME;Mariani S;Pasierski ...
Academic Journal
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Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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Despite evidence suggesting the benefit of prophylactic regional antibiotic delivery (...
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Regional antibiotic delivery for sternal wound infection prophylaxis a systematic review and meta-analysis of randomized controlled trials.
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Despite evidence suggesting the benefit of prophylactic regional antibiotic delivery (RAD) to sternal edges during cardiac surgery, it is seldom performed in clinical practice. The value of topical vancomycin and gentamicin for sternal wound infections (SWI) prophylaxis was further questioned by recent studies including randomized controlled trials (RCTs). The aim of this systematic review and meta-analysis was to comprehensively assess the safety and effectiveness of RAD to reduce the risk of SWI.We screened multiple databases for RCTs assessing the effectiveness of RAD (vancomycin, gentamicin) in SWI prophylaxis. Random effects meta-analysis was performed. The primary endpoint was any SWI; other wound complications were also analysed. Odds Ratios served as the primary statistical analyses. Trial sequential analysis (TSA) was performed.Thirteen RCTs (N = 7,719 patients) were included. The odds of any SWI were significantly reduced by over 50% with any RAD: OR (95%CIs): 0.49 (0.35-0.68); p < 0.001 and consistently reduced in vancomycin (0.34 [0.18-0.64]; p < 0.001) and gentamicin (0.58 [0.39-0.86]; p = 0.007) groups (p subgroup = 0.15). Similarly, RAD reduced the odds of SWI in diabetic and non-diabetic patients (0.46 [0.32-0.65]; p < 0.001 and 0.60 [0.44-0.83]; p = 0.002 respectively). Cumulative Z-curve passed the TSA-adjusted boundary for SWIs suggesting adequate power has been met and no further trials are needed. RAD significantly reduced deep (0.60 [0.43-0.83]; p = 0.003) and superficial SWIs (0.54 [0.32-0.91]; p = 0.02). No differences were seen in mediastinitis and mortality, however, limited number of studies assessed these endpoints. There was no evidence of systemic toxicity, sternal dehiscence and resistant strains emergence. Both vancomycin and gentamicin reduced the odds of cultures outside their respective serum concentrations' activity: vancomycin against gram-negative strains: 0.20 (0.01-4.18) and gentamicin against gram-positive strains: 0.42 (0.28-0.62); P < 0.001. Regional antibiotic delivery is safe and effectively reduces the risk of SWI in cardiac surgery patients.
(© 2024. The Author(s).)
(© 2024. The Author(s).)
Subject terms:
Humans - Sternum surgery - Sternum microbiology - Cardiac Surgical Procedures adverse effects - Surgical Wound Infection prevention & control - Randomized Controlled Trials as Topic - Anti-Bacterial Agents administration & dosage - Anti-Bacterial Agents therapeutic use - Antibiotic Prophylaxis methods - Vancomycin administration & dosage - Gentamicins administration & dosage - Gentamicins therapeutic useContent provider:
MEDLINE
Antibiotics vs. bacteria : fighting the resistance.
Electronic Government Doc
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2018
Available at Online freely available Government Documents (USU and USU Eastern)
Cotrimoxazole and targeted antibiotic prophylaxis for transrectal prostate biopsy: a single-center study.
Academic Journal
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Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE
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Jahnen M;Amiel T;Kirchoff F;Büchler JW;Herkommer K;Rothe K;Meissner VH;Gsch...
Academic Journal
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Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE
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Purpose: The recent restriction on the use of fluoroquinolones for prophylaxis by the ...
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Cotrimoxazole and targeted antibiotic prophylaxis for transrectal prostate biopsy: a single-center study.
Publisher: Springer International Country of Publication: Germany NLM ID: 8307716 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-8726 (Electronic) Linking ISSN: 07244983 NLM ISO Abbreviation: World J Urol Subsets: MEDLINE
Purpose: The recent restriction on the use of fluoroquinolones for prophylaxis by the European Commission has left a gap in clear recommendations for practical antibiotic prophylaxis (PAP) for transrectal prostate biopsy (TRPB). This analysis investigated the viability of cotrimoxazole for PAP in TRPB.
Methods: This analysis included n = 697 patients who underwent TRPB for suspected prostate cancer (PCa). All patients received either empiric PAP with four doses of cotrimoxazole 960 mg or targetedantibiotic prophylaxis in case of a positive rectal or urine screening for multiresistant gram-negatives. Infectious complications after TRPB, microbiological findings, and clinical characteristics were evaluated. A multivariable logistic regression model was calculated to identify variables associated with infectious complications.
Results: Of the cohort, 86% (600/697) received PAP with cotrimoxazole, 1% (8/697) received cotrimoxazole plus an additionalantibiotic , 4% (28/697) received amoxicillin + clavulanic acid, 4% (28/697) received fluoroquinolones, and 5% (33/697) received a single shot intravenous antibiotic prophylaxis with meropenem or piperacillin + tazobactam due to multiresistant microbiological findings in either pre-interventional urine culture or rectal swab. Infectious complications occurred in 2.6% (18/697) of patients. Fever was noted in 89% (16/18) of cases. Inpatient treatment was given to 67% (12/18) of affected patients, with 38% (7/18) having positive blood cultures, identifying cotrimoxazole-resistant E. coli strains in six out of seven cases. Multivariable logistic regression analysis revealed no clinically significant variables, including PAP with cotrimoxazole, as independent risk factors for an infectious complication.
Conclusions: Using cotrimoxazole as PAP for TRPB in cases without multiresistant gram-negatives in pre-interventional urine cultures or rectal swabs seems feasible and practical.
(© 2024. The Author(s).)
Methods: This analysis included n = 697 patients who underwent TRPB for suspected prostate cancer (PCa). All patients received either empiric PAP with four doses of cotrimoxazole 960 mg or targeted
Results: Of the cohort, 86% (600/697) received PAP with cotrimoxazole, 1% (8/697) received cotrimoxazole plus an additional
Conclusions: Using cotrimoxazole as PAP for TRPB in cases without multiresistant gram-negatives in pre-interventional urine cultures or rectal swabs seems feasible and practical.
(© 2024. The Author(s).)
Subject terms:
Humans - Male - Aged - Middle Aged - Anti-Bacterial Agents therapeutic use - Prostatic Neoplasms pathology - Retrospective Studies - Biopsy methods - Biopsy adverse effects - Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use - Antibiotic Prophylaxis methods - Prostate pathology - Rectum microbiologyContent provider:
MEDLINE
Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients.
Academic Journal
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Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9815642 Publication Model: Print Cited Medium: Internet ISSN: 1557-8674 (Electronic) Linking ISSN: 10962964 NLM ISO Abbreviation: Surg Infect (Larchmt) Subsets: MEDLINE
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Çelik Ekinci S;Yenilmez E;Akengin Öcal G;Sönmezer MÇ;Tarakçı A;Aygün C;Akda...
Academic Journal
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Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9815642 Publication Model: Print Cited Medium: Internet ISSN: 1557-8674 (Electronic) Linking ISSN: 10962964 NLM ISO Abbreviation: Surg Infect (Larchmt) Subsets: MEDLINE
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Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative ad...
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Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients.
Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9815642 Publication Model: Print Cited Medium: Internet ISSN: 1557-8674 (Electronic) Linking ISSN: 10962964 NLM ISO Abbreviation: Surg Infect (Larchmt) Subsets: MEDLINE
Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP.
Subject terms:
Adult - Humans - Anti-Bacterial Agents therapeutic use - Guideline Adherence - Prospective Studies - Turkey epidemiology - Antibiotic Prophylaxis methods - Surgical Wound Infection epidemiology - Surgical Wound Infection prevention & control - Surgical Wound Infection drug therapyContent provider:
MEDLINE
Antibiotics, FDA has encouraged development, but needs to clarify the role of draft guidance and develop qualified infectious disease product guidance : report to congressional requesters.
Electronic Government Doc
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2017
Available at Online freely available Government Documents (USU and USU Eastern)
Rethinking Perioperative Antibiotic Prophylaxis for Low-Risk Head and Neck Procedures.
Academic Journal
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Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE
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Nelson A;Baur JW;Lew A;Pettit NN;Nguyen CT
Academic Journal
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Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE
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Objective: For true clean-contaminated head and neck procedures, the literature suppor...
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Rethinking Perioperative Antibiotic Prophylaxis for Low-Risk Head and Neck Procedures.
Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE
Objective: For true clean-contaminated head and neck procedures, the literature supports ≤24 hours of perioperative antibiotics . However, there are certain otolaryngology procedures with low surgical site infection (SSI) risk for which there is negligible benefit from antibiotic prophylaxis. The objective of this evaluation was to describe antibiotic use and adherence to evidence-based institutional guidelines in low-risk head and neck procedures.
Methods: This was a single-center, retrospective cohort study of patients undergoing low-risk clean-contaminated head and neck procedures whereinantibiotic prophylaxis was not indicated, based on evidence-based institutional guidelines.
Results: Among the 291 included patients, perioperativeantibiotics were unnecessarily administered in 29% of patients. Among patients who received antibiotics , 76% received preoperative antibiotics and 41% received postoperative antibiotics , for a median duration of 7 days. There were no significant differences in SSIs, mortality, and length of stay for those receiving perioperative antibiotics versus those not receiving perioperative antibiotics .
Conclusion: These data highlight the need forantibiotic stewardship interventions and partnerships between antibiotic stewardship teams and surgical services.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Methods: This was a single-center, retrospective cohort study of patients undergoing low-risk clean-contaminated head and neck procedures wherein
Results: Among the 291 included patients, perioperative
Conclusion: These data highlight the need for
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Subject terms:
Humans - Retrospective Studies - Surgical Wound Infection prevention & control - Antibiotic Prophylaxis methods - Anti-Bacterial Agents therapeutic useContent provider:
MEDLINE
Effect of prolonged antibiotic prophylaxis on the occurrence of surgical site wound infection after instant breast reconstruction: A meta-analysis.
Academic Journal
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Publisher: Blackwell Pub Country of Publication: England NLM ID: 101230907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-481X (Electronic) Linking ISSN: 17424801 NLM ISO Abbreviation: Int Wound J Subsets: MEDLINE
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Jin L;Ba T
Academic Journal
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Publisher: Blackwell Pub Country of Publication: England NLM ID: 101230907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-481X (Electronic) Linking ISSN: 17424801 NLM ISO Abbreviation: Int Wound J Subsets: MEDLINE
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The purpose of the meta-analysis was to evaluate and compare the effects of prolonged ...
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Effect of prolonged antibiotic prophylaxis on the occurrence of surgical site wound infection after instant breast reconstruction: A meta-analysis.
Publisher: Blackwell Pub Country of Publication: England NLM ID: 101230907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-481X (Electronic) Linking ISSN: 17424801 NLM ISO Abbreviation: Int Wound J Subsets: MEDLINE
The purpose of the meta-analysis was to evaluate and compare the effects of prolonged antibiotic prophylaxis on the occurrence of surgical site wound infection after instant breast reconstruction. The results of this meta-analysis were analysed, and the odds ratio (OR) and mean difference with 95% confidence intervals (CIs) were calculated using dichotomous or contentious random- or fixed-effect models. For the current meta-analysis, 18 examinations spanning from 2009 to 2023 were included, encompassing 19 301 females with instant breast reconstruction. Systemic antibiotic prophylaxis had a significantly lower surgical site wound infection rate (OR, 0.85; 95% CI, 0.75-0.98, p = 0.02) compared with the standard of care after instant breast reconstruction in females. Topical antibiotic prophylaxis had a significantly lower surgical site wound infection rate (OR, 0.26; 95% CI, 0.13-0.52, p < 0.001) compared with the standard of care after instant breast reconstruction in females. The examined data revealed that systemic and topical antibiotic prophylaxis had a significantly lower surgical site wound infection rate compared with the standard of care after instant breast reconstruction in females. However, given that several examinations had a small sample size, consideration should be given to their values.
(© 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.)
(© 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.)
