QTc prolongation and diastolic dysfunction in cirrhosis patients with higher Child -Pugh score .
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Asian Journal of Medical Sciences. Oct2023, Vol. 14 Issue 10, p227-234. 8p.
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Salve, Chandrakant;Kuldeep, Jaiprakash;Mahor, Dinesh Singh
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Asian Journal of Medical Sciences. Oct2023, Vol. 14 Issue 10, p227-234. 8p.
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Serum uric acid level in chronic liver disease and its correlation with Child –Pugh score in a tertiary care hospital from South India.
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Journal of Family Medicine & Primary Care. Nov2023, Vol. 12 Issue 11, p2696-2701. 6p.
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Noklang, Samuel;Noklang, Imjungba;Kaumudi Chirumamilla, Sri;Kannauje, Panka...
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Journal of Family Medicine & Primary Care. Nov2023, Vol. 12 Issue 11, p2696-2701. 6p.
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CORELATIONS BETWEEN THE VALUE OF SERUM CHOLINESTERASE AND CHILD -PUGH AND MELD-NA SCORES IN CIRRHOTIC PATIENTS.
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Internal Medicine / Medicină Internă. 2022, Vol. 19 Issue 4, p7-15. 9p.
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Stancu, George;Sorohan, Bogdan;Toma, Letiția;Iliescu, Laura Elena
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Internal Medicine / Medicină Internă. 2022, Vol. 19 Issue 4, p7-15. 9p.
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QTc prolongation and diastolic dysfunction in cirrhosis patients with higher Child -Pugh score
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Asian Journal of Medical Sciences, Vol 14, Iss 10, Pp 227-234 (2023)
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Chandrakant Salve;Jaiprakash Kuldeep;Dinesh Singh Mahor
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Asian Journal of Medical Sciences, Vol 14, Iss 10, Pp 227-234 (2023)
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Background: Cirrhosis is associated with numerous cardiac abnormalities, which include...
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QTc prolongation and diastolic dysfunction in cirrhosis patients with higher Child -Pugh score
Asian Journal of Medical Sciences, Vol 14, Iss 10, Pp 227-234 (2023)
Background: Cirrhosis is associated with numerous cardiac abnormalities, which include increased cardiac output, left ventricular diastolic dysfunction, increased wall thickness of cardiac chambers, and pulmonary arterial hypertension. Without further identified cardiac disorders, cirrhotic cardiomyopathy (CCM) is a chronic cardiac dysfunction with an impaired contractile reaction to stress stimuli, impeded diastolic relaxation, and electrophysiological anomalies with a prolonged QT interval. In chronic hepatic disease, echocardiography is a non-invasive method for detecting CCM. Aims and Objectives: The focus was to examine the link between cardiac dysfunction and conduction disturbances in cirrhosis individuals and the extent of the disorder. Materials and Methods: A case–control investigation was conducted at a Medical College. The research involved a cohort of 50 patients and an equal number of 50 healthy controls. The Child -Pugh (CP) Score was utilized to evaluate the degree of liver cirrhosis severity. Bazett’s formula was utilized to compute the QTc interval. The 2D echocardiography revealed the presence of diastolic dysfunction, as evidenced by the E/A ratio. Results: Of 50 patients, 37 (74%) were male, 13 (26%) were female, and the mean age of the patients was 51.76±9.89 years. The E/A ratio in the control group had a mean value of 1.10±0.19, whereas in the cases, it had a mean value of 0.94±0.20. A statistically significant relationship was observed between the control and cases, with a P-value of less than 0.0001. QTc interval between control with a mean value of 382.9±47.34 ms and cases with a mean value of 431.6±62.84 ms was found statistically significant with P
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child–pugh score - cirrhosis - cirrhotic cardiomyopathy - diastolic dysfunction - qtc interval - MedicineContent provider:
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Safety of endoscopic retrograde cholangiopancreatography (ERCP) in cirrhosis compared to non-cirrhosis and effect of Child -Pugh score on post-ERCP complications: a systematic review...
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Clinical Endoscopy. Sep2023, Vol. 56 Issue 5, p578-589. 12p.
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Tarar, Zahid Ijaz;Farooq, Umer;Gandhi, Mustafa;Saleem, Saad;Daglilar, Ebube...
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Clinical Endoscopy. Sep2023, Vol. 56 Issue 5, p578-589. 12p.
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Safety of endoscopic retrograde cholangiopancreatography (ERCP) in cirrhosis compared to non-cirrhosis and effect of Child -Pugh score on post-ERCP complications: a systematic review...
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Clinical Endoscopy, Vol 56, Iss 5, Pp 578-589 (2023)
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Zahid Ijaz Tarar;Umer Farooq;Mustafa Gandhi;Saad Saleem;Ebubekir Daglilar
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Clinical Endoscopy, Vol 56, Iss 5, Pp 578-589 (2023)
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Background/Aims The safety of endoscopic retrograde cholangiopancreatography (ERCP) in...
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Safety of endoscopic retrograde cholangiopancreatography (ERCP) in cirrhosis compared to non-cirrhosis and effect of Child -Pugh score on post-ERCP complications: a systematic review...
Clinical Endoscopy, Vol 56, Iss 5, Pp 578-589 (2023)
Background/Aims The safety of endoscopic retrograde cholangiopancreatography (ERCP) in hepatic cirrhosis and the impact of Child -Pugh class on post-ERCP complications need to be better studied. We investigated the post-ERCP complication rates in patients with cirrhosis compared with those without cirrhosis. Methods We conducted a literature search of relevant databases to identify studies that reported post-ERCP complications in patients with hepatic cirrhosis. Results Twenty-four studies comprising 28,201 patients were included. The pooled incidence of post-ERCP complications in cirrhosis was 15.5% (95% confidence interval [CI], 11.8%–19.2%; I2=96.2%), with an individual pooled incidence of pancreatitis 5.1% (95% CI, 3.1%–7.2%; I2=91.5%), bleeding 3.6% (95% CI, 2.8%–4.5%; I2=67.5%), cholangitis 2.9% (95% CI, 1.9%–3.8%; I2=83.4%), and perforation 0.3% (95% CI, 0.1%–0.5%; I2=3.7%). Patients with cirrhosis had a greater risk of post-ERCP complications (risk ratio [RR], 1.41; 95% CI, 1.16–1.71; I2=56.3%). The risk of individual odds of adverse events between cirrhosis and non-cirrhosis was as follows: pancreatitis (RR, 1.25; 95% CI, 1.06–1.48; I2=24.8%), bleeding (RR, 1.94; 95% CI, 1.59–2.37; I2=0%), cholangitis (RR, 1.15; 95% CI, 0.77–1.70; I2=12%), and perforation (RR, 1.20; 95% CI, 0.59–2.43; I2=0%). Conclusions Cirrhosis is associated with an increased risk of post-ERCP pancreatitis, bleeding, and cholangitis.
Subject terms:
child-pugh - cholangitis - cirrhosis - endoscopic retrograde cholangiopancreatography - hemorrhage - pancreatitis - Internal medicine - RC31-1245 - Diseases of the digestive system. Gastroenterology - RC799-869Content provider:
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Jamil, Zubia;Perveen, Shahida;Khalid, Samreen;Aljuaid, Mohammed;Shahzad, Me...
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Journal of Clinical Medicine. Nov2022, Vol. 11 Issue 22, p6654. 11p.
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CLIF-C AD score predicts survival benefit from pre-emptive TIPS in individuals with Child -Pugh B cirrhosis and acute variceal bleeding
Lv, Yong;Bai, Wei;Zhu, Xuan;Xue, Hui;Zhao, Jianbo;Zhuge, Yuzheng;Sun, Junhu...
Determination of hepatic extraction fraction with gadoxetate low‐temporal resolution DCE‐MRI‐based deconvolution analysis: validation with ALBI score and Child ‐Pugh class
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Journal of Medical Radiation Sciences. April, 2023, Vol. 70, p48, 58 p.
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Phonlakrai, Monchai;Ramadan, Saadallah;Simpson, John;Gholizadeh, Neda;Arm, ...
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Journal of Medical Radiation Sciences. April, 2023, Vol. 70, p48, 58 p.
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LRFNet: A deep learning model for the assessment of liver reserve function based on Child ‐Pugh score and CT image
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In Computer Methods and Programs in Biomedicine August 2022 223
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Huang, Zhiwei;Zhang, Guo;Liu, Jiong;Huang, Mengping;Zhong, Lisha;Shu, Jian
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In Computer Methods and Programs in Biomedicine August 2022 223
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Prognostic value of a predictive score based on functional parameters for clinical outcome in patients with decompensated cirrhosis of the liver.
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Medicinski Glasnik. Feb2024, Vol. 21 Issue 1, p57-62. 6p.
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Mujkanović, Jasminka;Ljuca, Kenana;Tursunović, Amir;Ljuca, Nadina;Džananovi...
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Medicinski Glasnik. Feb2024, Vol. 21 Issue 1, p57-62. 6p.
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Évaluation et impact -pronostique de la fonction hépatique des patients sous traitement systémique pour un carcinome hépatocellulaire avancé.
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Hépato-Gastro & Oncologie Digestive. dec2023, Vol. 30 Issue 10, p1053-1058. 6p.
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Delhoume, Victoria;Khaldi, Marion;Salimon, Maëva;Touchefeu, Yann
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Hépato-Gastro & Oncologie Digestive. dec2023, Vol. 30 Issue 10, p1053-1058. 6p.
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Salvage living donor liver transplantation versus repeat liver resection for patients with recurrent hepatocellular carcinoma and Child -Pugh class A liver cirrhosis: A propensity score -matched...
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In American Journal of Transplantation January 2022 22(1):165-176
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Yoon, Young-In;Song, Gi-Won;Lee, SungGyu;Moon, DeokBog;Hwang, Shin;Kang, Wo...
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In American Journal of Transplantation January 2022 22(1):165-176
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Correlations between the value of serum cholinesterase and Child -Pugh and Meld-Na scores in cirrhotic patients
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Romanian Journal of Infectious Diseases, Vol 25, Iss 2, Pp 62-66 (2022)
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George Stancu;Bogdan Sorohan;George Gherlan;Letitia Toma;Laura Elena Iliesc...
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Romanian Journal of Infectious Diseases, Vol 25, Iss 2, Pp 62-66 (2022)
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To determine the degree of the liver failure in cirrhotic patients we use serum liver ...
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Correlations between the value of serum cholinesterase and Child -Pugh and Meld-Na scores in cirrhotic patients
Romanian Journal of Infectious Diseases, Vol 25, Iss 2, Pp 62-66 (2022)
To determine the degree of the liver failure in cirrhotic patients we use serum liver function tests In contrast with tests, serum cholinesterase values are low in liver failure. Purpose of the study is to establish if serum cholinesterase corelates with the level of liver disfunction. According to the Child -Pugh Score , 70 patients with chronic liver disease were selected and grouped into 3 categories. Serum cholinesterase, serum albumin and International Normalized Ratio were analyzed and correlations between them were calculated. We observed that the cholinesterase levels tend to decrease according to the Child -Pugh score , lowest in the C group and highest in the A group. The cholinesterase correlated with the albumin serum levels, value of MELD-Na score and Child -Pugh score and did not corelate to INR. In conclusion, serum cholinesterase can be used as an indicator of the liver disfunction grade.
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serum cholinesterase - liver cirrhosis - child-pugh score - albumin - meld-na score - Medicine - Infectious and parasitic diseases - RC109-216Content provider:
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Huang, Po-Han;Yu, Jen;Chu, Yin-Yi;Lin, Yang-Hsiang;Yeh, Chau-Ting
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Journal of Clinical Medicine. May2022, Vol. 11 Issue 9, p2550-2550. 11p.
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Comparison of Modified Child -pugh (MCP), Albumin-bilirubin (ALBI), and Child -pugh (CP) score for predicting of survival in Hepatocellular...
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In Bulletin du Cancer October 2021 108(10):931-939
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Liu, YouShun;Cheng, Cong;Zhou, HuaBang;Hu, ShouZi;Wang, Hao;Xie, QiaoHua;Le...
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In Bulletin du Cancer October 2021 108(10):931-939
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Serum uric acid level in chronic liver disease and its correlation with Child –Pugh score in a tertiary care hospital from South India
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Journal of Family Medicine and Primary Care, Vol 12, Iss 11, Pp 2696-2701 (2023)
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Samuel Noklang;Imjungba Noklang;Sri Sai Kaumudi Chirumamilla;Pankaj K Kanna...
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Journal of Family Medicine and Primary Care, Vol 12, Iss 11, Pp 2696-2701 (2023)
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Background: Chronic liver disease (CLD) is one of the important causes of morbidity an...
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Serum uric acid level in chronic liver disease and its correlation with Child –Pugh score in a tertiary care hospital from South India
Journal of Family Medicine and Primary Care, Vol 12, Iss 11, Pp 2696-2701 (2023)
Background: Chronic liver disease (CLD) is one of the important causes of morbidity and mortality in our country, and since the damage to the liver is irreversible, we have to look for many severity markers or predictors for the prognosis of the patient. In this study, we have tried to correlate the level of serum uric acid (UA) with the severity of CLD presented as a Child –Pugh score . Methods: A cross-sectional observational study was conducted at Vijayanagar Institute of Medical Science (VIMS), Ballari, Karnataka, from October 2015 to June 2017 in the Department of General Medicine. Fifty patients diagnosed with CLD, aged between 18 and 65 years, of either gender, were enrolled in the study. Serum UA levels were measured, and liver function and coagulation parameters were assessed. A statistical analysis was performed to evaluate the association between serum UA levels, liver function test, and coagulation parameters. Results: In our study, the mean serum UA level was 6.52 mg/dl and was raised in patients with CLD in correlation to its severity. Alcoholic liver disease (ALD) was the most common etiology for CLD (80%) followed by hepatitis B (Hep B) virus infection (12%) and hepatitis C (Hep C) virus infection (6%). Serum UA levels increased as the Child –Turcotte–Pugh (CTP) score increased. The mean UA level in CTP class C was 8.29 mg/dl. Various parameters such as serum aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase, total bilirubin, international normalized ratio (INR), calcium, and albumin were significantly associated with serum UA levels in CLD patients. Conclusion: The correlation between rising blood UA levels and the Child –Pugh score shows that UA estimate may be a valid and affordable indicator for assessing the extent of liver cirrhosis in CLD.
Subject terms:
alanine transaminase (alt) - alcohol liver disease (ald) - aspartate aminotransferase (ast) - child–turcotte–pugh score (ctp) - chronic liver disease (cld) - international normalized ratio (inr) - uric acid (ua) - MedicineContent provider:
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ALBI and Child -Pugh score in predicting mortality in chronic liver disease patients secondary to alcohol - A retrospective comparative study.
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Asian Journal of Medical Sciences. Sep/Oct2019, Vol. 10 Issue 5, p33-36. 4p.
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B. S., Nagaraja;R., Madhumathi;S. B., Sanjeet;K. J., Umesh;S., Nandish Kuma...
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Asian Journal of Medical Sciences. Sep/Oct2019, Vol. 10 Issue 5, p33-36. 4p.
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Alteration of prognostic efficacy of albumin‐bilirubin grade and Child ‐Pugh score according to liver fibrosis in hepatocellular carcinoma patients with Child ‐Pugh ...
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Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 127-134 (2022)
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Tatsunori Miyata;Yo‐ichi Yamashita;Kota Arima;Takaaki Higashi;Hiromitsu Hay...
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Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 127-134 (2022)
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Abstract Background The albumin‐bilirubin (ALBI) grade was developed to predict the pr...
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Alteration of prognostic efficacy of albumin‐bilirubin grade and Child ‐Pugh score according to liver fibrosis in hepatocellular carcinoma patients with Child ‐Pugh ...
Annals of Gastroenterological Surgery, Vol 6, Iss 1, Pp 127-134 (2022)
Abstract Background The albumin‐bilirubin (ALBI) grade was developed to predict the prognosis of patients with hepatocellular carcinoma (HCC), which can stratify the prognosis even in HCC patients with Child ‐Pugh A. We evaluated the prognostic efficacy of the ALBI grade and Child ‐Pugh classification in HCC patients with Child ‐Pugh A stratified by the presence or absence of advanced fibrosis or a preoperative biomarker for advanced fibrosis. Methods We retrospectively analyzed 490 consecutive HCC patients with Child ‐Pugh A who underwent initial hepatectomies. The accuracy of prognostic prediction using both models was compared by the presence or absence of advanced fibrosis (F3‐4) and its predictor, the preoperative platelet count (PLT). Results The prognostic accuracy of the ALBI grade was better in patients without advanced fibrosis (F3‐4; likelihood ratio: 4.39, corrected Akaike information criterion [AICc]: 453.0, P = .074), but Child ‐Pugh score was better in the advanced fibrosis group (likelihood ratio: 10.67, AICc: 915.2, P = .0014). In the high PLT group (≥140 × 103/μL), the prognostic accuracy using the ALBI grade was better in overall survival (OS) and relapse‐free survival (RFS), but in the low PLT group, the Child ‐Pugh score was the more accurate model in OS and RFS. Conclusions Depending on the degree of fibrosis or preoperative PLT, the ALBI grade and Child ‐Pugh score may provide more accurate prognoses after initial hepatectomy in HCC patients with Child ‐Pugh A.
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advanced fibrosis - Child‐Pugh score - HCC - prognosis - The ALBI grade - Surgery - RD1-811 - Diseases of the digestive system. Gastroenterology - RC799-869Content provider:
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University of Missouri School of Medicine Researchers Release New Data on Cholangitis [Safety of endoscopic retrograde cholangiopancreatography (ERCP) in cirrhosis compared to non-cirrhosis and effect of Child -Pugh ...
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Obesity, Fitness & Wellness Week. October 14, 2023, 5850
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Obesity, Fitness & Wellness Week. October 14, 2023, 5850
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