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[16:21:02] Processing page 'Oncomatryx' — edithistory * Expand citation: Molecular Basis of Metastasis * initial authors exist, not correcting pages * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 [..> rifydoi] . Checking that DOI 10.1056/NEJMra0805239 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting pages * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * Expand citation: Tumor-stroma interactions in pancreatic ductal adenocarcinoma * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 [..> rifydoi] . Checking that DOI 10.1158/1535-7163.MCT-06-0686 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * Expand citation: Effective Immunoconjugate Therapy in Cancer Models Targeting a Serine Protease of Tumor Fibroblasts * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting year * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting pages * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 [..> rifydoi] . Checking that DOI 10.1158/1078-0432.CCR-07-5211 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting year * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting pages * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * Expand citation: Isolation and partial characterization of nigrin b, a non-toxic novel type 2 ribosome-inactivating protein from the bark of ''Sambucus'' nigra L * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * initial authors exist, not correcting last10 * initial authors exist, not correcting first10 [..> rifydoi] . Checking that DOI 10.1007/BF00028990 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * initial authors exist, not correcting last10 * initial authors exist, not correcting first10 * Expand citation: Targeting a marker of the tumour neovasculature using a novel anti-human CD105-immunotoxin containing the non-toxic type 2 ribosome-inactivating protein nigrin b * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * initial authors exist, not correcting last10 * initial authors exist, not correcting first10 * initial authors exist, not correcting title * initial authors exist, not correcting doi [..> rifydoi] . Checking that DOI 10.1016/j.canlet.2007.05.012 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * initial authors exist, not correcting last10 * initial authors exist, not correcting first10 * initial authors exist, not correcting title * initial authors exist, not correcting doi * Expand citation: Occurrence and new procedure of preparation of nigrin, an antiribosomal lectin present in elderberry bark * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 [..> rifydoi] . Checking that DOI 10.1016/j.foodres.2011.06.004 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * Expand citation: Use of Ribosome-Inactivating Proteins from Sambucus for the Construction of Immunotoxins and Conjugates for Cancer Therapy * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 [..> rifydoi] . Checking that DOI 10.3390/toxins3050420 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * Expand citation: Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 [..> rifydoi] . Checking that DOI 10.1002/1097-0215(200102)9999:9999<::AID-IJC1170>3.0.CO;2-U is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. [..> add] + Adding pmid * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * Expand citation: Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse * initial authors exist, not correcting pmc * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting year * initial authors exist, not correcting issue * initial authors exist, not correcting volume * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting author1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> rossref] - Checking CrossRef database for doi. [..> indpmid] - Searching PubMed... * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting pmc * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting year * initial authors exist, not correcting issue * initial authors exist, not correcting volume * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting author1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * Expand citation: Generation of human high-affinity antibodies specific for the fibroblast activation protein by guided selection * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 [..> rifydoi] . Checking that DOI 10.1046/j.1432-1327.2001.02046.x is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting doi * initial authors exist, not correcting pmid * initial authors exist, not correcting pages * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting last1 * initial authors exist, not correcting first1 * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 * initial authors exist, not correcting last7 * initial authors exist, not correcting first7 * initial authors exist, not correcting last8 * initial authors exist, not correcting first8 * initial authors exist, not correcting last9 * initial authors exist, not correcting first9 * Expand citation: Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library * initial authors exist, not correcting last1 * initial authors exist, not correcting first * initial authors exist, not correcting pmid * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 [..> rifydoi] . Checking that DOI 10.1016/j.bbrc.2004.03.074 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last1 * initial authors exist, not correcting first * initial authors exist, not correcting pmid * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting journal * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * Expand citation: In vitro characterization of binding and stability of single-chain Fv Ni-NTA-liposomes * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting title * initial authors exist, not correcting doi * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 [..> rifydoi] . Checking that DOI 10.1080/10611860600864018 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting title * initial authors exist, not correcting doi * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * Expand citation: Single-chain Fv immunoliposomes for the targeting of fibroblast activation protein-expressing tumor stromal cells * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 [..> rifydoi] . Checking that DOI 10.1080/10611860701453034 is operational... DOI ok. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy [..> yadsabs] - Skipping AdsAbs database: not in slow mode [..> indpmid] - Searching PubMed... no results. nothing found. * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * Initial authors exist, skipping authorlink in tidy * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting doi * initial authors exist, not correcting title * initial authors exist, not correcting year * initial authors exist, not correcting pages * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * Expand citation: Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice * initial authors exist, not correcting last * initial authors exist, not correcting first * initial authors exist, not correcting journal * initial authors exist, not correcting volume * initial authors exist, not correcting issue * initial authors exist, not correcting year * initial authors exist, not correcting doi * initial authors exist, not correcting pages * initial authors exist, not correcting pmid * initial authors exist, not correcting title * initial authors exist, not correcting last2 * initial authors exist, not correcting first2 * initial authors exist, not correcting last3 * initial authors exist, not correcting first3 * initial authors exist, not correcting last4 * initial authors exist, not correcting first4 * initial authors exist, not correcting last5 * initial authors exist, not correcting first5 * initial authors exist, not correcting last6 * initial authors exist, not correcting first6 [..> rifydoi] . Checking that DOI 10.1016/j.jim.2008.08.008 is operational... 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'''Oncomatryx''' Biopharma S. L. is a pharmaceutical biotechnology company that develops personalized treatments against invasive cancer as well as tests for its early detection. Established by Laureano Simón, PhD, Oncomatryx thus engages twofold in the fight against invasive kinds of cancer, such as pancreatic cancer or invasive breast [[cancer]], all of which have high mortality rates.

Oncomatryx's research focuses on peritumoral [[stromal cell|stroma]], which has been found to take part in promoting cancer invasiveness and curtailing treatment efficacy.<ref name="New English Journal Medicine">{{cite journal
| pages = 2814–2823|doi=10.1056/NEJMra0805239|pmid=19109576|title=Molecular Basis of Metastasis|journal=New England Journal of Medicine|volume=359|issue=26|year=2008|last1=Chiang|first1=Anne C.|last2=Massagué|first2=Joan}}
</ref>

== Laureano Simón ==
Laureano Simón began his business career in 2000 with the creation of Progenika Biopharma S.A., a personalized medicine company which was acquired by Grifols in February 2013.<ref>[http://www.biospace.com/News/grifols-acquires-60-pct-stake-in-progenika-for-48/289880 Biospace.com]</ref>

Dr. Simón holds a Ph.D. in Chemical Sciences (Molecular Biology) by the  [[Universidad Autónoma de Madrid]], a Master’s degree in Biotechnology by the [[University of Navarra]], an MSc by the “[[University of Wisconsin-Madison]]” and a Bachelor’s degree in Pharmacy by the [[University of Santiago de Compostela]]. He has patented, among others, clinical products such as BLOODchip and LIPOchip.
He has also published many articles in scientific journals and has received several awards throughout his career, among which it is worth noting European Eurowards Entrepreneurship Award in 2004, [[Ernst & Young’s]] Most Innovative Entrepreneur of the Year in 2010 and [http://www.businessawardseurope.com/RDH/2012|the Ruban D´Honneur of the European Business Awards] -HSBC Bank in 2011. He has participated in science and technology development plans from both the Spanish and the Basque Governments and has contributed to several private foundations, like the Carlos Slim Institute of Health, the Fundación Pedro Barrié de la Maza and the BBVA Foundation.

== Research and development ==
The company bases its R&D on the recent discovery that tumor cells generate changes in the cells that surround them as well as in the extracellular matrix, facilitating invasion metastases.<ref>{{cite journal
|doi=10.1158/1535-7163.MCT-06-0686 
| pmid =17406031
| pages =1186–1197
| title =Tumor-stroma interactions in pancreatic ductal adenocarcinoma
| journal =Molecular Cancer Therapeutics
| volume =6
| issue =4
| year =2007
| last1 =Mahadevan
| first1 =D.
| last2 =von Hoff
| first2 =D. D.
}}</ref><ref>{{cite journal|last=Ostermann|first=E.|journal=Clin. Cancer Research|year=2008|volume=14|issue=14|pages=4584–4592|doi=10.1158/1078-0432.CCR-07-5211|title=Effective Immunoconjugate Therapy in Cancer Models Targeting a Serine Protease of Tumor Fibroblasts|last2=Garin-Chesa|first2=P.|last3=Heider|first3=K. H.|last4=Kalat|first4=M.|last5=Lamche|first5=H.|last6=Puri|first6=C.|last7=Kerjaschki|first7=D.|last8=Rettig|first8=W. J.|last9=Adolf|first9=G. R.}}</ref>
Oncomatryx and its collaborators and advisors have proved that peritumoral stroma, which is constituted by mesenchymal cells and extracellular matrix, plays a key role in tumor invasiveness and metastasis, at the same time being a physical barrier that prevents  anti-cancer agents from reaching tumor cells.<ref>{{cite journal
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| last2 = Citores
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}}</ref><ref>{{cite journal
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| title = Targeting a marker of the tumour neovasculature using a novel anti-human CD105-immunotoxin containing the non-toxic type 2 ribosome-inactivating protein nigrin b
| doi = 10.1016/j.canlet.2007.05.012
}}</ref><ref>{{cite journal
 | doi=10.1016/j.foodres.2011.06.004
| pages =2798–2805
| title =Occurrence and new procedure of preparation of nigrin, an antiribosomal lectin present in elderberry bark
| journal =Food Research International
| volume =44
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| year =2011
| last1 =Ferreras
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| last2 =Citores
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| last3 =Iglesias
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| last4 =Jiménez
| first4 =Pilar
| last5 =Souza
| first5 =Aíla Maria
| last6 =Gayoso
| first6 =Manuel José
| last7 =Girbés
| first7 =Tomás
}}</ref><ref>{{cite journal
 |doi=10.3390/toxins3050420| pages =420–441
| title =Use of Ribosome-Inactivating Proteins from Sambucus for the Construction of Immunotoxins and Conjugates for Cancer Therapy
| journal =Toxins
| volume =3
| issue =12
| year =2011
| last1 =Ferreras
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}}</ref><ref>{{cite journal
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| title =Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas
| journal =International Journal of Cancer
| volume =92
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| last1 =Mersmann
| first1 =Michael
| last2 =Schmidt
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| last4 =w�Est
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| last8 =Pfizenmaier
| first8 =Klaus
| last9 =Moosmayer
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}}</ref><ref>{{cite journal
 |pmc=1950057|title=Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse|journal=Molecular Medicine|year= 2001|issue=7|volume=7
 | pages =461–469|pmid=11683371|author1=Brocks|first1=B|last2=Garin-Chesa|first2=P|last3=Behrle|first3=E|last4=Park|first4=J. E.|last5=Rettig|first5=W. J.|last6=Pfizenmaier|first6=K|last7=Moosmayer|first7=D}}</ref><ref>{{cite journal
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| last6 =Garin-Chesa
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}}</ref><ref>{{cite journal
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}}</ref><ref>{{cite journal
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}}</ref>

Oncomatryx is developing a new generation of biological anti-tumor drugs, combining cytotoxic molecules and monoclonal antibodies specifically directed towards tumor associated stroma.

=== Scientific Advisory Board ===
*'''Franco Dosio''', Ph.D. Professor, Department of Drug Science and Technology. Università degli Studi di Torino. Torino, Italy.
*'''Tomás Girbés''', Ph.D. Professor. Departament of Nutrition and Bromatology. Facultad de Medicina. Universidad de Valladolid, CINAD. Valladolid, Spain.
*'''Manuel Hidalgo''', M.D., Ph.D. Head of Gastrointestinal Cancer Clinical Research unit. Centro Nacional de Investigaciones Oncológicas. Madrid, Spain.
*'''Roland E. Kontermann''', Ph.D. Mildred-Scheel Professor. Biomedical Engineering unit. Institut für Zellbiologie und Immunologie. Universität Stuttgart. Germany.
*'''Klaus Pfizenmaier''', Ph.D. Professor, Director of Institute. Cell Biology unit. Institut für Zellbiologie und Immunologie. Universität Stuttgart. Germany.
*'''Andrea Bolognesi''', Phd. Professor. Department of Experimental Diagnosticand Speciality Medicine. Universitá Bologna, Italy.

=== Collaborations ===
Oncomatryx collaborates with the [http://www.uni-stuttgart.de/izi/ Institut für Zell Biologie und Immunologie] of the University of Stuttgart,<ref>[http://www.businesswire.com/news/home/20121211005808/en/Oncomatrix-Signs-Agreement-University-Stuttgart-Develop-Drugs#.U0QVgDiKC1s Business Wire]</ref><ref>http://www.clinicaspace.com/News/oncomatrix-signs-an-agreement-with-the-university/281846 ClinicaSpace</ref> the University of Valladolid, Hospital Universitario Marqués de Valdecilla, Hospital Universitario Central de Asturias, the Centro Nacional de Investigaciones Oncológicas, National Jewish Health and Breast Cancer Research among others.

== Developments and products of the company ==

=== Diagnostic tests ===
Currently, invasive cancer is associated with a very short life expectancy . In the case of pancreatic cancer, which unfortunately is almost always already in invasive stages at the time of diagnosis, only between 1% and 4% of patients survive for five years after diagnosis.<ref>{{cite web|url=http://www.spaintechnology.com/technology/en/global-navigation/sectores/tecnologia-industrial/noticias/NEW2013225241_EN_US.html?subsector=370 |title=Oncomatrix designs a test that shows if breast cancer will metastasize |publisher=Spaintechnology.com |date=2013-07-25 |accessdate=2014-04-13}}</ref>

Oncomatryx has developed molecular diagnostic tests to predict the invasiveness of breast tumors (DMTXbreastScan) and pancreas, colon, lung, and head and neck tumors (DMTXinvaScan). These tests have already been used successfully in hospitals in Andalucia, Asturias, Cantabria, Catalonia, Galicia, Madrid, Navarre, the Basque Country and Valencia in Spain. In addition, the universities of Columbia (USA), Munich (Germany) and Copenhagen (Denmark) have also proven their high sensitivity and specificity. DMTXinvaScan and DMTXbreastScan were presented to the international medical community at the Annual Conference of the United States and Canadian Academy of Pathology, held in Baltimore, USA, in March 2013. Specifically, DMTXbreastScan helps to determine, at the moment of first diagnosis, if a breast tumor has the capacity to develop metastases. This test, which is already being used in USA hospitals such as Johns Hopkins Hospital in Baltimore and Cedars Sinai Hospital in Los Angeles, has 93.5% sensitivity and 94.2% specificity in detecting invasive breast tumors in biopsies. In addition, it helps to predict if a benign lesion of the breast, such as a papilloma, will turn into a malignant tumor, so the treatment can be adapted more effectively for each patient.<ref>[http://www.businesswire.com/news/home/20130304005995/en/Oncomatrix-Launches-Immunohistochemistry-Kit-Diagnose-Prognose-Tumor#.U0QelDiKC1sç Business Wire]</ref><ref>[http://www.clinicaspace.com/News/spanish-company-oncomatrix-develops-a-test-that/301151 Clinicaspace]</ref>

=== Antitumor treatments ===
Antitumor drugs developed by Oncomatryx, which specifically target the peritumoral stroma, are currently in pre-clinical development phase and will enter clinical trials in  2015. 
For this purpose, the company has reached an agreement with the U.S. National Jewish Health hospital and Case Western Reserve University <ref>http://www.businesswire.com/news/home/20120619006072/en/Oncomatrix-National-Jewish-Health-Case-Western-Reserve#.U0QXMjiKC1s Businesswire</ref><ref>[http://www.biospace.com/News/oncomatrix-national-jewish-health-and-case-western/264420 Biospace]</ref><ref>[http://www.biotech-finances.com/fr/cp-174627.html Biotech Finances]</ref> whereby Oncomatyx will use a human protein, Cystatin-C, as a principle asset for the development of drugs against  invasive breast cancer.
 
Oncomatryx has also signed collaboration agreements with the Universität  Stuttgart (Germany), the Universidad de Valladolid (Spain), and other biotech companies for the development of immunotoxins and [[Antibody-drug conjugate|ADCs]] targeted specifically towards the stromal component of tumors. This strategy allows for attacking directly the cells responsible for invasion and metastasis in cancer. These immunotoxins and [[Antibody-drug conjugate|ADCs]] are specifically directed against two proteins, known as MTX1 and MTX2, which are expressed only in the peritumoral stroma that surround the tumor and facilitates its progression and metastasis.<ref>{{cite web|url=http://www.fiercebiotech.com/press-releases/oncomatrix-signs-agreement-university-stuttgart-develop-new-drugs-treating |title=Oncomatrix Signs an Agreement with the University of Stuttgart to Develop New Drugs for Treating Tumor Metastases |publisher=FierceBiotech |date= |accessdate=2014-04-13}}</ref>

== References ==
{{Reflist}}

[[Category:Biotechnology]]