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ID:
1301389
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14.139.85.199
Article:
Protecting group
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Revision as of 19:45, 17 September 2012
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→Carboxylic acid protecting groups
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Revision as of 11:32, 29 October 2012
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→Alcohol protecting groups
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Line 13:
Line 13:
* [[Benzyl]] (Bn, Bnl) - Removed by [[hydrogenolysis]]. Bn group is widely used in sugar and nucleoside chemistry.
* [[Benzyl]] (Bn, Bnl) - Removed by [[hydrogenolysis]]. Bn group is widely used in sugar and nucleoside chemistry.
* [[Chloroalkyl ether|β-Methoxyethoxymethyl ether]] (MEM) - Removed by acid.
* [[Chloroalkyl ether|β-Methoxyethoxymethyl ether]] (MEM) - Removed by acid.
* [[Dimethoxytrityl]]{{Anchor|DMT}}, [bis-(4-methoxyphenyl)phenylmethyl] (DMT) - Removed by weak acid. DMT group is widely used for protection of 5'-hydroxy group in nucleosides,
particularly
in [[Oligonucleotide synthesis#Phosphoramidite building blocks|oligonucleotide synthesis]].
* [[Dimethoxytrityl]]{{Anchor|DMT}}, [bis-(4-methoxyphenyl)phenylmethyl] (DMT) - Removed by weak acid. DMT group is widely used for protection of 5'-hydroxy group in nucleosides,
partiavinash loves soujanyacularly
in [[Oligonucleotide synthesis#Phosphoramidite building blocks|oligonucleotide synthesis]].
* [[Methoxymethyl ether]] (MOM) - Removed by acid.
* [[Methoxymethyl ether]] (MOM) - Removed by acid.
* Methoxytrityl [(4-methoxyphenyl)diphenylmethyl, MMT) - Removed by acid and hydrogenolysis.
* Methoxytrityl [(4-methoxyphenyl)diphenylmethyl, MMT) - Removed by acid and hydrogenolysis.
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