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50 publications found

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Group #1

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues[1]Anastasia Tziridis, [2]Daniel Rauh, [3]Piotr Neumann, [4]Petr Kolenko, [5]Anja Menzel, [6]Ulrike Bräuer, [7]Christian Ursel, [8]Peter Steinmetzer, [9]Jörg Stürzebecher, [10]Andrea Schweinitz, [11]Torsten Steinmetzer, [12]Milton T Stubbs [Full author list]Biological Chemistry [missing]DOI: 10.1515/HSZ-2014-0158 [ORCID]
PubMed: 25003390 [ORCID]
drug discovery [missing]2014-07-01
Use of IHC and newly designed matriptase inhibitors to elucidate the role of matriptase in pancreatic ductal adenocarcinoma[1]Kerstin Uhland, [2]Bence Siphos, [3]Christoph Arkona, [4]Maj Schuster, [5]Bernhard Petri, [6]Peter Steinmetzer, [7]Friedemann Mueller, [8]Andrea Schweinitz, [9]Torsten Steinmetzer, [10]Andreas Van De Locht [Full author list]International Journal of Oncology [missing]PubMed: 19578749 [ORCID]
adenocarcinoma [missing]2009-08-01
Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors[1]Andrea Schweinitz, [2]Daniel Dönnecke, [3]Alexander Ludwig, [4]Peter Steinmetzer, [5]Alexander Schulze, [6]Joscha Kotthaus, [7]Silvia Wein, [8]Bernd Clement, [9]Torsten Steinmetzer [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2009.02.047 [ORCID]
PubMed: 19250826 [ORCID]
2009-02-14
Modification of the N-terminal sulfonyl residue in 3-amidinophenylalanine-based matriptase inhibitors[1]Torsten Steinmetzer, [2]Daniel Dönnecke, [3]Martin Korsonewski, [4]Claudia Neuwirth, [5]Peter Steinmetzer, [6]Alexander Schulze, [7]Sebastian Martin Saupe, [8]Andrea Schweinitz [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2008.11.019 [ORCID]
PubMed: 19036586 [ORCID]
2008-11-13
In vitro inhibition of matriptase prevents invasive growth of cell lines of prostate and colon carcinoma[1]Diana Förbs, [2]Stefan Thiel, [3]Maria C Stella, [4]Anne Stürzebecher, [5]Andrea Schweinitz, [6]Torsten Steinmetzer, [7]Jörg Stürzebecher, [8]Kerstin Uhland [Full author list]International Journal of Oncology [missing]PubMed: 16142324 [ORCID]
2005-10-01
Progress in the development of synthetic thrombin inhibitors as new orally active anticoagulants[1]Torsten Steinmetzer, [2]Jörg Stürzebecher [Full author list]Current Medicinal Chemistry [missing]DOI: 10.2174/0929867043364540 [ORCID]
PubMed: 15379714 [ORCID]
anticoagulation [missing]2004-09-01
Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents[1]Andrea Schweinitz, [2]Torsten Steinmetzer, [3]Ingo J Banke, [4]Matthias J E Arlt, [5]Anne Stürzebecher, [6]Oliver Schuster, [7]Andreas Geissler, [8]Helmut Giersiefen, [9]Ewa Zeslawska, [10]Uwe Jacob, [11]Achim Krüger, [12]Jörg Stürzebecher [Full author list]Journal of Biological Chemistry [missing]DOI: 10.1074/JBC.M314151200 [ORCID]
PubMed: 15150279 [ORCID]
pharmacokinetics [missing]; plasminogen [missing]2004-05-18
Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors[1]Ingo J Banke, [2]Matthias J E Arlt, [3]Caroline Pennington, [4]Charlotte Kopitz, [5]Torsten Steinmetzer, [6]Andrea Schweinitz, [7]Bernd Gansbacher, [8]James P Quigley, [9]Dylan R. Edwards, [10]Jörg Stürzebecher, [11]Achim Krüger [Full author list]Biological Chemistry [missing]DOI: 10.1515/BC.2003.168 [ORCID]
PubMed: 14669995 [ORCID]
2003-10-01
Influence of structural variations in peptidomimetic 4-amidinophenylalanine-derived thrombin inhibitors on plasma clearance and biliary excretion in rats[1]Jörg Hauptmann, [2]Torsten Steinmetzer, [3]Helmut Vieweg, [4]Peter Wikström, [5]Jürg Stürzebecher [Full author list]Pharmaceutical Research [missing]DOI: 10.1023/A:1016426724831 [ORCID]
PubMed: 12180535 [ORCID]
2002-07-01
Structure-activity relationships of new NAPAP-analogs[1]Torsten Steinmetzer, [2]Andrea Schweinitz, [3]Sebastian Künzel, [4]Peter Wikström, [5]Jörg Hauptmann, [6]Jörg Stürzebecher [Full author list]Journal of Enzyme Inhibition and Medicinal Chemistry [missing]PubMed: 12420761 [ORCID]
2002-04-01
The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage[1]Rainer Friedrich, [2]Torsten Steinmetzer, [3]Robert Huber, [4]Jörg Stürzebecher, [5]Wolfram Bode [Full author list]Journal of Molecular Biology [missing]DOI: 10.1006/JMBI.2001.5394 [ORCID]
PubMed: 11884127 [ORCID]
2002-03-01

Group #2

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Surface glycoprotein of Borna disease virus mediates virus spread from cell to cell[1]Frank Lennartz, [2]Karen Bayer, [3]Nadine Czerwonka, [4]Yinghui Lu, [5]Kristine Kehr, [6]Manuela Hirz, [7]Torsten Steinmetzer, [8]Wolfgang Garten, [9]Christiane Herden [Full author list]Cellular Microbiology [missing]DOI: 10.1111/CMI.12515 [ORCID]
PubMed: 26332529 [ORCID]
Borna disease [missing]; pathogen spread [missing]2015-09-02
Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics[1]Wolfgang Garten, [2]Carolin Braden, [3]Annika Arendt, [4]Catharina Peitsch, [5]Joanna Baron, [6]Yinghui Lu, [7]Kerstin Pawletko, [8]Kornelia Hardes, [9]Torsten Steinmetzer, [10]Eva Böttcher-Friebertshäuser [Full author list]European Journal of Cell Biology [missing]DOI: 10.1016/J.EJCB.2015.05.013 [ORCID]
PubMed: 26095298 [ORCID]
2015-06-01Torsten Steinmetzer (Q86899440; 10 items)
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells[1]Yinghui Lu, [2]Kornelia Hardes, [3]Sven O Dahms, [4]Eva Böttcher-Friebertshäuser, [5]Torsten Steinmetzer, [6]Manuel E Than, [7]Hans-Dieter Klenk, [8]Wolfgang Garten [Full author list]Antiviral Research [missing]DOI: 10.1016/J.ANTIVIRAL.2015.05.006 [ORCID]
PubMed: 26022200 [ORCID]
avian influenza [missing]; oseltamivir [missing]; ribavirin [missing]2015-05-26Torsten Steinmetzer (Q86899440; 10 items)
Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation[1]Daniela Meyer, [2]Frank Sielaff, [3]Maya Hammami, [4]Eva Böttcher-Friebertshäuser, [5]Wolfgang Garten, [6]Torsten Steinmetzer [Full author list]Biochemical Journal [missing]DOI: 10.1042/BJ20130101 [ORCID]
PubMed: 23527573 [ORCID]
transmembrane protein [missing]2013-06-01
Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses[1]Joanna Baron, [2]Carolin Tarnow, [3]Deborah Mayoli-Nüssle, [4]Eva Schilling, [5]Daniela Meyer, [6]Maya Hammami, [7]Folker Schwalm, [8]Torsten Steinmetzer, [9]Guan Yi, [10]Wolfgang Garten, [11]Hans-Dieter Klenk, [12]Eva Böttcher-Friebertshäuser [Full author list]Journal of Virology [missing]DOI: 10.1128/JVI.02320-12 [ORCID]
PubMed: 23192872 [ORCID]
2012-11-28
Hemagglutinin activating host cell proteases provide promising drug targets for the treatment of influenza A and B virus infections[1]Eva Böttcher-Friebertshäuser, [2]Yinghui Lu, [3]Daniela Meyer, [4]Frank Sielaff, [5]Torsten Steinmetzer, [6]Hans-Dieter Klenk, [7]Wolfgang Garten [Full author list]Vaccine [missing]DOI: 10.1016/J.VACCINE.2012.10.001 [ORCID]
PubMed: 23072892 [ORCID]
2012-10-13
Purification of the proprotein convertase furin by affinity chromatography based on PC-specific inhibitors[1]Miriam Kuester, [2]Gero L Becker, [3]Kornelia Hardes, [4]Iris Lindberg, [5]Torsten Steinmetzer, [6]Manuel E Than [Full author list]Biological Chemistry [missing]DOI: 10.1515/BC.2011.100 [ORCID]
PubMed: 21875402 [ORCID]
2011-08-30Torsten Steinmetzer (Q86899440; 10 items)
Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT.[1]Frank Sielaff, [2]Eva Böttcher-Friebertshäuser, [3]Daniela Meyer, [4]Sebastian M Saupe, [5]Ines M Volk, [6]Wolfgang Garten, [7]Torsten Steinmetzer [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2011.06.033 [ORCID]
PubMed: 21741839 [ORCID]
2011-06-21
New furin inhibitors based on weakly basic amidinohydrazones[1]Frank Sielaff, [2]Manuel E Than, [3]Dorian Bevec, [4]Iris Lindberg, [5]Torsten Steinmetzer [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2010.11.092 [ORCID]
PubMed: 21168329 [ORCID]
2010-11-25Torsten Steinmetzer (Q86899440; 10 items)
Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors[1]Eva Böttcher-Friebertshäuser, [2]Catharina Freuer, [3]Frank Sielaff, [4]Sarah Schmidt, [5]Markus Eickmann, [6]Jennifer Uhlendorff, [7]Torsten Steinmetzer, [8]Hans-Dieter Klenk, [9]Wolfgang Garten [Full author list]Journal of Virology [missing]DOI: 10.1128/JVI.00140-10 [ORCID]
PubMed: 20237084 [ORCID]
2010-03-17
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics[1]Gero L Becker, [2]Frank Sielaff, [3]Manuel E Than, [4]Iris Lindberg, [5]Sophie Routhier, [6]Robert Day, [7]Yinghui Lu, [8]Wolfgang Garten, [9]Torsten Steinmetzer [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM9012455 [ORCID]
PubMed: 20038105 [ORCID]
2010-02-01Torsten Steinmetzer (Q86899440; 10 items)
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition[1]Eva Böttcher, [2]Catharina Freuer, [3]Torsten Steinmetzer, [4]Hans-Dieter Klenk, [5]Wolfgang Garten [Full author list]Vaccine [missing]DOI: 10.1016/J.VACCINE.2009.03.029 [ORCID]
PubMed: 19840668 [ORCID]
2009-10-01

Group #3

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
First Structure-Activity Relationship of 17β-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme[1]Florian Braun, [2]Nicole Bertoletti, [3]Gabriele Möller, [4]Jerzy Adamski, [5]Torsten Steinmetzer, [6]Mohamed Salah, [7]Ahmed S Abdelsamie, [8]Chris J van Koppen, [9]Andreas Heine, [10]Gerhard Klebe, [11]Sandrine Marchais-Oberwinkler [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/ACS.JMEDCHEM.6B01436 [ORCID]
PubMed: 27933965 [ORCID]
crystal structure [missing]2016-11-18Torsten Steinmetzer (Q86899440; 10 items)
Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines[1]Stefan Hinkes, [2]André Wuttke, [3]Sebastian M Saupe, [4]Teodora Ivanova, [5]Sebastian Wagner, [6]Anna Knörlein, [7]Andreas Heine, [8]Gerhard Klebe, [9]Torsten Steinmetzer [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/ACS.JMEDCHEM.6B00606 [ORCID]
PubMed: 27280436 [ORCID]
2016-07-14Torsten Steinmetzer (Q86899440; 10 items)
Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors.[1]Alexander Maiwald, [2]Maya Hammami, [3]Sebastian Wagner, [4]Andreas Heine, [5]Gerhard Klebe, [6]Torsten Steinmetzer [Full author list]Journal of Enzyme Inhibition and Medicinal Chemistry [missing]DOI: 10.3109/14756366.2016.1172574 [ORCID]
PubMed: 27168215 [ORCID]
2016-05-11Torsten Steinmetzer (Q86899440; 10 items)
Beyond heparinization: design of highly potent thrombin inhibitors suitable for surface coupling[1]Torsten Steinmetzer, [2]Bernhard Baum, [3]Adam Biela, [4]Gerhard Klebe, [5]Götz Nowak, [6]Elke Bucha [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201200292 [ORCID]
PubMed: 22907907 [ORCID]
2012-11-01
Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect[1]Adam Biela, [2]Frank Sielaff, [3]Felix Terwesten, [4]Andreas Heine, [5]Torsten Steinmetzer, [6]Gerhard Klebe [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM300337Q [ORCID]
PubMed: 22612268 [ORCID]
hydrophobicity [missing]; ligand binding [missing]2012-07-12Torsten Steinmetzer (Q86899440; 10 items)
A new strategy for the development of highly potent and selective plasmin inhibitors[1]Sebastian M Saupe, [2]Torsten Steinmetzer [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM2011996 [ORCID]
PubMed: 22276953 [ORCID]
2012-01-25

Group #4

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket[1]Sven O Dahms, [2]Kornelia Hardes, [3]Torsten Steinmetzer, [4]Manuel E Than [Full author list]Biochemistry [missing]DOI: 10.1021/ACS.BIOCHEM.7B01124 [ORCID]
PubMed: 29314830 [ORCID]
2018-01-26Torsten Steinmetzer (Q86899440; 10 items)
Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism[1]Sven O Dahms, [2]Marcelino Arciniega, [3]Torsten Steinmetzer, [4]Robert Huber, [5]Manuel E Than [Full author list]Proceedings of the National Academy of Sciences of the United States of America [missing]DOI: 10.1073/PNAS.1613630113 [ORCID]
PubMed: 27647913 [ORCID]
2016-09-19Torsten Steinmetzer (Q86899440; 10 items)
X-ray structures of human furin in complex with competitive inhibitors[1]Sven O Dahms, [2]Kornelia Hardes, [3]Gero L Becker, [4]Torsten Steinmetzer, [5]Hans Brandstetter, [6]Manuel E Than [Full author list]ACS Chemical Biology [missing]DOI: 10.1021/CB500087X [ORCID]
PubMed: 24666235 [ORCID]
2014-04-01Torsten Steinmetzer (Q86899440; 10 items)

Group #5

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin[1]Kornelia Hardes, [2]Teodora Ivanova, [3]Bastian Thaa, [4]Gerald M McInerney, [5]Tove Irene Klokk, [6]Kirsten Sandvig, [7]Sebastian Künzel, [8]Iris Lindberg, [9]Torsten Steinmetzer [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201700108 [ORCID]
PubMed: 28334511 [ORCID]
Chikungunya virus [missing]2017-04-04Torsten Steinmetzer (Q86899440; 10 items)
Novel Furin Inhibitors with Potent Anti-infectious Activity[1]Kornelia Hardes, [2]Gero L Becker, [3]Yinghui Lu, [4]Sven O Dahms, [5]Susanne Köhler, [6]Wolfgang Beyer, [7]Kirsten Sandvig, [8]Hiroyuki Yamamoto, [9]Iris Lindberg, [10]Lisa Walz, [11]Veronika von Messling, [12]Manuel E Than, [13]Wolfgang Garten, [14]Torsten Steinmetzer [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201500103 [ORCID]
PubMed: 25974265 [ORCID]
2015-07-01Torsten Steinmetzer (Q86899440; 10 items)
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases[1]Gero L Becker, [2]Yinghui Lu, [3]Kornelia Hardes, [4]Boris Strehlow, [5]Christine Levesque, [6]Iris Lindberg, [7]Kirsten Sandvig, [8]Udo Bakowsky, [9]Robert Day, [10]Wolfgang Garten, [11]Torsten Steinmetzer [Full author list]Journal of Biological Chemistry [missing]DOI: 10.1074/JBC.M111.332643 [ORCID]
PubMed: 22539349 [ORCID]
2012-04-26

Group #6

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis[1]Ina Coburger, [2]Yvonne Schaub, [3]Dirk Roeser, [4]Kornelia Hardes, [5]Patrick Maeder, [6]Nina Klee, [7]Torsten Steinmetzer, [8]Diana Imhof, [9]Wibke E Diederich, [10]Manuel E Than [Full author list]MicrobiologyOpen [missing]DOI: 10.1002/MBO3.358 [ORCID]
PubMed: 27038342 [ORCID]
transmembrane protein [missing]2016-04-01Torsten Steinmetzer (Q86899440; 10 items)
Novel insights into structure and function of factor XIIIa-inhibitor tridegin[1]Miriam Böhm, [2]Charlotte A Bäuml, [3]Kornelia Hardes, [4]Torsten Steinmetzer, [5]Dirk Roeser, [6]Yvonne Schaub, [7]Manuel E Than, [8]Arijit Biswas, [9]Diana Imhof [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM501058G [ORCID]
PubMed: 25415134 [ORCID]
2014-12-05Torsten Steinmetzer (Q86899440; 10 items)
Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa[1]Miriam Böhm, [2]Toni Kühl, [3]Kornelia Hardes, [4]Richard Coch, [5]Christoph Arkona, [6]Bernhard Schlott, [7]Torsten Steinmetzer, [8]Diana Imhof [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201100405 [ORCID]
PubMed: 22162181 [ORCID]
2011-12-07Torsten Steinmetzer (Q86899440; 10 items)

Group #7

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
A Fluorescent-Labeled Phosphono Bisbenzguanidine As an Activity-Based Probe for Matriptase.[1]Daniela Häußler, [2]Anna-Christina Schulz-Fincke, [3]Anna-Madeleine Beckmann, [4]Aline Keils, [5]Erik Gilberg, [6]Martin Mangold, [7]Jürgen Bajorath, [8]Marit Stirnberg, [9]Torsten Steinmetzer, [10]Michael Gütschow [Full author list]Chemistry—A European Journal [missing]DOI: 10.1002/CHEM.201700319 [ORCID]
PubMed: 28370501 [ORCID]
2017-03-28
Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases[1]Norbert Furtmann, [2]Daniela Häußler, [3]Tamara Scheidt, [4]Marit Stirnberg, [5]Torsten Steinmetzer, [6]Jürgen Bajorath, [7]Michael Gütschow [Full author list]Chemistry—A European Journal [missing]DOI: 10.1002/CHEM.201503534 [ORCID]
PubMed: 26625703 [ORCID]
2015-12-02
Identification of the first low-molecular-weight inhibitors of matriptase-2.[1]Mihiret Tekeste Sisay, [2]Torsten Steinmetzer, [3]Marit Stirnberg, [4]Eva Maurer, [5]Maya Hammami, [6]Jürgen Bajorath, [7]Michael Gütschow [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM100183E [ORCID]
PubMed: 20684597 [ORCID]
2010-08-01

Group #8

Matched potential author: Torsten Steinmetzer - author of 10 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication[1]Jenny Kouretova, [2]M Zouhir Hammamy, [3]Anton Epp, [4]Kornelia Hardes, [5]Stephanie Kallis, [6]Linlin Zhang, [7]Rolf Hilgenfeld, [8]Ralf Bartenschlager, [9]Torsten Steinmetzer [Full author list]Journal of Enzyme Inhibition and Medicinal Chemistry [missing]DOI: 10.1080/14756366.2017.1306521 [ORCID]
PubMed: 28385094 [ORCID]
West Nile virus [missing]; Dengue virus [missing]2017-12-01Torsten Steinmetzer (Q86899440; 10 items)
Synthesis and characterization of novel fluorogenic substrates of coagulation factor XIII-A.[1]Kornelia Hardes, [2]M Zouhir Hammamy, [3]Torsten Steinmetzer [Full author list]Analytical Biochemistry [missing]DOI: 10.1016/J.AB.2013.07.043 [ORCID]
PubMed: 23933241 [ORCID]
2013-08-09
Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease[1]M Zouhir Hammamy, [2]Caroline Haase, [3]Maya Hammami, [4]Rolf Hilgenfeld, [5]Torsten Steinmetzer [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201200497 [ORCID]
PubMed: 23307694 [ORCID]
West Nile virus [missing]2013-02-01

Group #9

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
In vitro characterization of TMPRSS2 inhibition in IPEC-J2 cells[1]Erzsebet Pászti-Gere, [2]Eszter Czimmermann, [3]Gabriella Ujhelyi, [4]Peter Balla, [5]Alexander Maiwald, [6]Torsten Steinmetzer [Full author list]Journal of Enzyme Inhibition and Medicinal Chemistry [missing]DOI: 10.1080/14756366.2016.1193732 [ORCID]
PubMed: 27277342 [ORCID]
2016-06-09
Interaction exists between matriptase inhibitors and intestinal epithelial cells[1]Erzsebet Pászti-Gere, [2]Réka Fanni Barna, [3]Gabriella Ujhelyi, [4]Torsten Steinmetzer [Full author list]Journal of Enzyme Inhibition and Medicinal Chemistry [missing]DOI: 10.3109/14756366.2015.1060483 [ORCID]
PubMed: 26118419 [ORCID]
2015-06-29

Misc

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms[1]David J Wilkinson, [2]Angela Habgood, [3]Heather K Lamb, [4]Paul Thompson, [5]Alastair R Hawkins, [6]Antoine Désilets, [7]Richard Leduc, [8]Torsten Steinmetzer, [9]Maya Hammami, [10]Melody S Lee, [11]Charles S Craik, [12]Sharon Watson, [13]Hua Lin, [14]Jennifer M Milner, [15]Andrew D Rowan [Full author list]Arthritis & Rheumatology [missing]DOI: 10.1002/ART.40133 [ORCID]
PubMed: 28464560 [ORCID]
osteoarthritis [missing]2017-05-02
Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction[1]Mike Jaegle, [2]Torsten Steinmetzer, [3]Jörg Rademann [Full author list]Angewandte Chemie International Edition [missing]DOI: 10.1002/ANIE.201611547 [ORCID]
PubMed: 28199769 [ORCID]
2017-02-15
Time-domain in vivo near infrared fluorescence imaging for evaluation of matriptase as a potential target for the development of novel, inhibitor-based tumor therapies[1]Joanna Napp, [2]Christian Dullin, [3]Friedemann Müller, [4]Kerstin Uhland, [5]Jean Bernhard Petri, [6]Andreas van de Locht, [7]Torsten Steinmetzer, [8]Frauke Alves [Full author list]International Journal of Cancer [missing]DOI: 10.1002/IJC.25405 [ORCID]
PubMed: 20473895 [ORCID]
2010-10-01
Synthetic urokinase inhibitors as potential antitumor drugs[1]Torsten Steinmetzer [Full author list]IDrugs: the Investigational Drugs Journal [missing]PubMed: 12789617 [ORCID]
2003-02-01

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Torsten Steinmetzerresearcher10ORCID: 0000-0001-6523-4754
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