Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
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IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression | [1]Chen-Hui Wang, [2]CunJin Zhang, [3]Bradley N Martin, [4]Katarzyna Bulek, [5]Zizhen Kang, [6]Junjie Zhao, [7]Guanglin Bian, [8]Julie A Carman, [9]Ji Gao, [10]Ashok Dongre, [11]Haibo Xue, [12]Stephen D Miller, [13]Youcun Qian, [14]Dolores Hambardzumyan, [15]Tom Hamilton, [16]Richard M Ransohoff, [17]Xiaoxia Li [Full author list] | Nature Communications [missing] | DOI: 10.1038/NCOMMS15508 [ORCID] PubMed: 28561022 [ORCID]
| oligodendrocyte [missing] | 2017-05-31 | Xiaoxia Li (Q88125485; 13 items)
|
Antigen-specific CD8+ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin | [1]Yikun Yao, [2]Siyuan Chen, [3]Mengtao Cao, [4]Xing Fan, [5]Tao Yang, [6]Yin Huang, [7]Xinyang Song, [8]Yongqin Li, [9]Lilin Ye, [10]Nan Shen, [11]Yufang Shi, [12]Yufang Shi, [13]Xiaoxia Li, [14]Feng Wang, [15]Youcun Qian [Full author list] | Nature Communications [missing] | DOI: 10.1038/NCOMMS15402 [ORCID] PubMed: 28537251 [ORCID]
| inflammasome complex [missing] | 2017-05-24 | |
The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity | [1]Xinyang Song, [2]Xiao He, [3]Xiaoxia Li, [4]Youcun Qian [Full author list] | Cellular and Molecular Immunology [missing] | DOI: 10.1038/CMI.2015.105 [ORCID] PubMed: 27018218 [ORCID]
| interleukins [missing] | 2016-07-01 | |
IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly | [1]Ryan Ferrao, [2]Hao Zhou, [3]Yibing Shan, [4]Qun Liu, [5]Qiubai Li, [6]David E Shaw, [7]Xiaoxia Li, [8]Hao Wu [Full author list] | Molecular Cell [missing] | DOI: 10.1016/J.MOLCEL.2014.08.006 [ORCID] PubMed: 25201411 [ORCID]
| cell biology [missing] | 2014-09-18 | |
The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling | [1]Ling Wu, [2]Chen-Hui Wang, [3]Bertrand Boisson, [4]Saurav Misra, [5]Patricia Rayman, [6]James H Finke, [7]Anne Puel, [8]Jean-Laurent Casanova, [9]Xiaoxia Li [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.1400715 [ORCID] PubMed: 25024377 [ORCID]
| | 2014-07-14 | Xiaoxia Li (Q88125485; 13 items)
|
Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling | [1]Bing Zhang, [2]Caini Liu, [3]Wen Qian, [4]Yue Han, [5]Xiaoxia Li, [6]Junpeng Deng [Full author list] | Acta Crystallographica Section D: Biological Crystallography [missing] | DOI: 10.1107/S1399004714005227 [ORCID] PubMed: 24816115 [ORCID]
| structural biology [missing]; ligand binding [missing] | 2014-05-01 | Xiaoxia Li (Q88125485; 13 items)
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MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. | [1]Minjia Yu, [2]Hao Zhou, [3]Junjie Zhao, [4]Nengming Xiao, [5]Sanjoy Roychowdhury, [6]David Schmitt, [7]Bingqing Hu, [8]Richard M Ransohoff, [9]Clifford V Harding, [10]Amy G. Hise, [11]Stanley L Hazen, [12]Anthony L DeFranco, [13]Paul L Fox, [14]Richard E Morton, [15]Paul E Dicorleto, [16]Maria Febbraio, [17]Laura E Nagy, [18]Jonathan D Smith, [19]Jian-an Wang, [20]Xiaoxia Li [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20131314 [ORCID] PubMed: 24752299 [ORCID]
| obesity [missing]; inflammation [missing]; endothelium [missing] | 2014-04-21 | Xiaoxia Li (Q88125485; 13 items)
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Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells | [1]Zizhen Kang, [2]Chenhui Wang, [3]Jarod Zepp, [4]Ling Wu, [5]Kevin Sun, [6]Junjie Zhao, [7]Unni Chandrasekharan, [8]Paul E DiCorleto, [9]Bruce D Trapp, [10]Richard M Ransohoff, [11]Xiaoxia Li [Full author list] | Nature Neuroscience [missing] | DOI: 10.1038/NN.3505 [ORCID] PubMed: 23995070 [ORCID]
| | 2013-09-01 | Xiaoxia Li (Q88125485; 13 items)
|
Crystal Structure of IL-17 Receptor B SEFIR Domain | [1]Bing Zhang, [2]Caini Liu, [3]Wen Qian, [4]Yue Han, [5]Xiaoxia Li, [6]Junpeng Deng [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.1202922 [ORCID] PubMed: 23355738 [ORCID]
| crystal structure [missing] | 2013-03-01 | Xiaoxia Li (Q88125485; 13 items)
|
IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production | [1]Hao Zhou, [2]Minjia Yu, [3]Koichi Fukuda, [4]Jinteak Im, [5]Peng Yao, [6]Wei Cui, [7]Katarzyna Bulek, [8]Jarod Zepp, [9]Youzhong Wan, [10]Tae Whan Kim, [11]Weiguo Yin, [12]Victoria Ma, [13]James Thomas, [14]Jun Gu, [15]Jian-an Wang, [16]Paul E DiCorleto, [17]Paul L Fox, [18]Jun Qin, [19]Xiaoxia Li [Full author list] | The EMBO Journal [missing] | DOI: 10.1038/EMBOJ.2013.2 [ORCID] PubMed: 23376919 [ORCID]
| toll-like receptor [missing]; TNF receptor-associated factor 6 [missing]; Interleukin-1 receptor-associated kinase 3 [missing]; Interleukin-1 receptor-associated kinase 4 [missing] | 2013-02-20 | Xiaoxia Li (Q88125485; 13 items)
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Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF) | [1]Dongxu Sun, [2]Michael Novotny, [3]Katarzyna Bulek, [4]Caini Liu, [5]Xiaoxia Li, [6]Thomas Hamilton [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI.2081 [ORCID] PubMed: 21822258 [ORCID]
| TNF receptor-associated factor 5 [missing]; Serine and arginine-rich splicing factor 1 [missing]; TRAF3 interacting protein 2 [missing] | 2011-09-01 | Xiaoxia Li (Q88125485; 13 items)
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The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation | [1]Katarzyna Bulek, [2]Caini Liu, [3]Shadi Swaidani, [4]Liwen Wang, [5]Richard C. Page, [6]Muhammet F. Gulen, [7]Tomasz Herjan, [8]Amina Abbadi, [9]Wen Qian, [10]Dongxu Sun, [11]Mark Lauer, [12]Vincent Hascall, [13]Saurav Misra, [14]Mark R. Chance, [15]Mark Aronica, [16]Thomas Hamilton, [17]Xiaoxia Li [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI.2080 [ORCID] PubMed: 21822257 [ORCID]
| inflammation [missing]; Inhibitor of kappaB kinase epsilon [missing]; TNF receptor-associated factor 5 [missing]; TNF receptor-associated factor 6 [missing]; TRAF3 interacting protein 2 [missing] | 2011-08-07 | Xiaoxia Li (Q88125485; 13 items)
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The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88 | [1]Bing He, [2]Raul Santamaria, [3]Weifeng Xu, [4]Montserrat Cols, [5]Kang Chen, [6]Irene Puga, [7]Meimei Shan, [8]Huabao Xiong, [9]James Bruce Bussel, [10]April Chiu, ..., [17]Jens Krause, [18]Graham Davies, [19]Xiaoxia Li, [20]Bodo Grimbacher, [21]Alessandro Plebani, ... [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI.1914 [ORCID] PubMed: 20676093 [ORCID]
| transmembrane protein [missing] | 2010-09-01 | |
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response | [1]Katarzyna Bulek, [2]Shadi Swaidani, [3]Jinzhong Qin, [4]Yi Lu, [5]Muhammet F Gulen, [6]Tomasz Herjan, [7]Booki Min, [8]Robert A Kastelein, [9]Mark Aronica, [10]Magdalena Kosz-Vnenchak, [11]Xiaoxia Li [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.0802729 [ORCID] PubMed: 19234154 [ORCID]
| | 2009-03-01 | Xiaoxia Li (Q88125485; 13 items)
|
Pyogenic bacterial infections in humans with MyD88 deficiency | [1]Horst von Bernuth, [2]Capucine Picard, [3]Zhongbo Jin, [4]Rungnapa Pankla, [5]Hui Xiao, [6]Cheng-Lung Ku, [7]Maya Chrabieh, [8]Imen Ben Mustapha, [9]Pegah Ghandil, [10]Yildiz Camcioglu, ..., [33]Jacques Banchereau, [34]Laurent Abel, [35]Xiaoxia Li, [36]Damien Chaussabel, [37]Anne Puel, ... [Full author list] | Science [missing] | DOI: 10.1126/SCIENCE.1158298 [ORCID] PubMed: 18669862 [ORCID]
| pyogenic bacterial infections due to MyD88 deficiency [missing] | 2008-08-01 | |
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation | [1]Hui Xiao, [2]Wen Qian, [3]Kirk Staschke, [4]Youcun Qian, [5]Grace Cui, [6]Li Deng, [7]Mariam Ehsani, [8]Xiliang Wang, [9]Yue-Wei Qian, [10]Zhijian Chen, [11]Raymond Gilmour, [12]Zhengfan Jiang, [13]Xiaoxia Li [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M706931200 [ORCID] PubMed: 18326498 [ORCID]
| cell biology [missing]; interleukins [missing]; NF-κB [missing] | 2008-03-07 | |
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity | [1]Cheng-Lung Ku, [2]Horst von Bernuth, [3]Capucine Picard, [4]Shen-Ying Zhang, [5]Huey-Hsuan Chang, [6]Kun Yang, [7]Maya Chrabieh, [8]Andrew C Issekutz, [9]Coleen K Cunningham, [10]John Gallin, ..., [25]David Speert, [26]Damien Sanlaville, [27]Xiaoxia Li, [28]Frederic Geissmann, [29]Eric Vivier, ... [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20070628 [ORCID] PubMed: 17893200 [ORCID]
| toll-like receptor [missing] | 2007-10-01 | |
Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses | [1]Kun Yang, [2]Anne Puel, [3]Shenying Zhang, [4]Celine Eidenschenk, [5]Cheng-Lung Ku, [6]Armanda Casrouge, [7]Capucine Picard, [8]Horst von Bernuth, [9]Brigitte Senechal, [10]Sabine Plancoulaine, ..., [20]Robert L Coffman, [21]Richard L Miller, [22]Xiaoxia Li, [23]Pierre Lebon, [24]Carlos Rodriguez-Gallego, ... [Full author list] | Immunity [missing] | DOI: 10.1016/J.IMMUNI.2005.09.016 [ORCID] PubMed: 16286015 [ORCID]
| virology [missing]; Toll like receptor 3 [missing]; toll-like receptor [missing]; Toll like receptor 9 [missing]; Toll like receptor 8 [missing]; Toll like receptor 7 [missing]; regulation of cytokine production [missing] | 2005-11-01 | |
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines | [1]Jochen Schmitz, [2]Alexander Owyang, [3]Elizabeth Oldham, [4]Yaoli Song, [5]Erin Murphy, [6]Terril K McClanahan, [7]Gerard Zurawski, [8]Mehrdad Moshrefi, [9]Jinzhong Qin, [10]Xiaoxia Li, [11]Daniel M Gorman, [12]J Fernando Bazan, [13]Robert A Kastelein [Full author list] | Immunity [missing] | DOI: 10.1016/J.IMMUNI.2005.09.015 [ORCID] PubMed: 16286016 [ORCID]
| interleukins [missing] | 2005-11-01 | |
SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms | [1]Jinzhong Qin, [2]Youcun Qian, [3]Jianhong Yao, [4]Cui Grace, [5]Xiaoxia Li [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M501363200 [ORCID] PubMed: 15866876 [ORCID]
| interleukins [missing]; toll-like receptor [missing]; negative regulation of lipopolysaccharide-mediated signaling pathway [missing]; Single Ig and TIR domain containing [missing] | 2005-07-01 | |
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival | [1]Youcun Qian, [2]Jinzhong Qin, [3]Grace Cui, [4]Mayumi Naramura, [5]E. Charles Snow, [6]Carl F. Ware, [7]Robert L. Fairchild, [8]Sidne A. Omori, [9]Robert C. Rickert, [10]Martin Scott, [11]Brian L. Kotzin, [12]Xiaoxia Li [Full author list] | Immunity [missing] | DOI: 10.1016/J.IMMUNI.2004.09.001 [ORCID] PubMed: 15485634 [ORCID]
| CD40 ligand [missing]; Tumor necrosis factor (ligand) superfamily, member 13b [missing]; TRAF3 interacting protein 2 [missing] | 2004-10-01 | |
Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA | [1]Shyamasree Datta, [2]Michael Novotny, [3]Xiaoxia Li, [4]Julie Tebo, [5]Thomas A Hamilton [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.173.4.2755 [ORCID] PubMed: 15294994 [ORCID]
| MYD88 innate immune signal transduction adaptor [missing]; 3'-UTR-mediated mRNA stabilization [missing]; TIR domain containing adaptor protein [missing] | 2004-08-15 | |
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta | [1]Zhengfan Jiang, [2]Tak W Mak, [3]Ganes Sen, [4]Xiaoxia Li [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0308496101 [ORCID] PubMed: 14982987 [ORCID]
| toll-like receptor [missing]; NF-κB [missing]; positive regulation of I-kappaB kinase/NF-kappaB signaling [missing]; Toll like receptor adaptor molecule 1 [missing]; Mitogen-activated protein kinase kinase kinase 7 [missing] | 2004-03-09 | |
Identification of a human NF-kappaB-activating protein, TAB3 | [1]Ge Jin, [2]Alison Klika, [3]Michelle Callahan, [4]Ben Faga, [5]Joel Danzig, [6]Zhengfan Jiang, [7]Xiaoxia Li, [8]George R Stark, [9]John Harrington, [10]Bruce Sherf [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0307314101 [ORCID] PubMed: 14766965 [ORCID]
| NF-κB [missing] | 2004-02-17 | |
Mutant human cells with constitutive activation of NF-kappaB | [1]Swati S Sathe, [2]Nywana Sizemore, [3]Xiaoxia Li, [4]Kalpa Vithalani, [5]Mairead Commane, [6]Shannon M Swiatkowski, [7]George R Stark [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0306812101 [ORCID] PubMed: 14691254 [ORCID]
| NF-κB [missing] | 2003-12-22 | |
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling | [1]David Wald, [2]Jinzhong Qin, [3]Zhendong Zhao, [4]Youcun Qian, [5]Mayumi Naramura, [6]Liping Tian, [7]Jennifer Towne, [8]John E Sims, [9]George R Stark, [10]Xiaoxia Li [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI968 [ORCID] PubMed: 12925853 [ORCID]
| interleukins [missing]; toll-like receptor [missing]; Toll like receptor 9 [missing]; Toll like receptor 5 [missing]; interleukin-1 receptor binding [missing]; Single Ig and TIR domain containing [missing]; Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain [missing] | 2003-08-17 | Xiaoxia Li (Q88125485; 13 items)
|
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR | [1]Zhengfan Jiang, [2]Maryam Zamanian-Daryoush, [3]Huiqing Nie, [4]Aristobolo M Silva, [5]Bryan R G Williams, [6]Xiaoxia Li [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M300562200 [ORCID] PubMed: 12609980 [ORCID]
| interleukins [missing]; toll-like receptor [missing] | 2003-05-09 | |
Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex | [1]Zhengfan Jiang, [2]H Jan Johnson, [3]Huiqing Nie, [4]Jinzhong Qin, [5]Timothy A Bird, [6]Xiaoxia Li [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M212112200 [ORCID] PubMed: 12496252 [ORCID]
| interleukins [missing] | 2003-03-28 | |
Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol | [1]Zhengfan Jiang, [2]Jun Ninomiya-Tsuji, [3]Youcun Qian, [4]Kunihiro Matsumoto, [5]Xiaoxia Li [Full author list] | Molecular and Cellular Biology [missing] | DOI: 10.1128/MCB.22.20.7158-7167.2002 [ORCID] PubMed: 12242293 [ORCID]
| cell biology [missing]; interleukins [missing]; phosphorylation [missing] | 2002-10-01 | |
Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells | [1]Youcun Qian, [2]Zhendong Zhao, [3]Zhengfan Jiang, [4]Xiaoxia Li [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.142294499 [ORCID] PubMed: 12089335 [ORCID]
| NF-κB [missing] | 2002-06-27 | |