Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
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TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology | [1]Yashaswini Kannan, [2]Jimena Perez-Lloret, [3]Yanda Li, [4]Lewis J Entwistle, [5]Hania Khoury, [6]Stamatia Papoutsopoulou, [7]Radma Mahmood, [8]Nuha R Mansour, [9]Stanley Ching-Cheng Huang, [10]Edward J Pearce, [11]Luiz Pedro S de Carvalho, [12]Steven C Ley, [13]Mark S Wilson [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.1005783 [ORCID] PubMed: 27487182 [ORCID]
| | 2016-08-03 | |
The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites | [1]Gerard E Kaiko, [2]Hyunji Ryu, [3]Olivia I Koues, [4]Patrick L Collins, [5]Lilianna Solnica-Krezel, [6]Edward J Pearce, [7]Erika L Pearce, [8]Eugene M Oltz, [9]Thaddeus S. Stappenbeck [Full author list] | Cell [missing] | DOI: 10.1016/J.CELL.2016.05.018 [ORCID] PubMed: 27264604 [ORCID]
| | 2016-05-31 | |
Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12 | [1]Bart Everts, [2]Roxane Tussiwand, [3]Leentje Dreesen, [4]Keke C Fairfax, [5]Stanley Ching-Cheng Huang, [6]Amber M Smith, [7]Christina M O'Neill, [8]Wing Y Lam, [9]Brian T Edelson, [10]Joseph F. Urban, [11]Kenneth M Murphy, [12]Edward J Pearce [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20150235 [ORCID] PubMed: 26712805 [ORCID]
| dendritic cell [missing] | 2015-12-28 | |
Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization | [1]Abhishek K Jha, [2]Stanley Ching-Cheng Huang, [3]Alexey Sergushichev, [4]Vicky Lampropoulou, [5]Yulia Ivanova, [6]Ekaterina Loginicheva, [7]Karina Chmielewski, [8]Kelly M Stewart, [9]Juliet Ashall, [10]Bart Everts, [11]Edward J Pearce, [12]Edward M Driggers, [13]Maxim N Artyomov [Full author list] | Immunity [missing] | DOI: 10.1016/J.IMMUNI.2015.02.005 [ORCID] PubMed: 25786174 [ORCID]
| macrophage [missing] | 2015-03-01 | |
Dendritic cell metabolism | [1]Edward J Pearce, [2]Bart Everts [Full author list] | Nature Reviews Immunology [missing] | DOI: 10.1038/NRI3771 [ORCID] PubMed: 25534620 [ORCID]
| dendritic cell [missing] | 2015-01-01 | |
Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis | [1]Marcia Nascimento, [2]Stanley C Huang, [3]Amber Smith, [4]Bart Everts, [5]Wing Lam, [6]Elizabeth Bassity, [7]Emmanuel L. Gautier, [8]Gwendalyn J. Randolph, [9]Edward J Pearce [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.1004282 [ORCID] PubMed: 25144366 [ORCID]
| inflammation [missing]; macrophage [missing]; schistosomiasis [missing] | 2014-08-21 | |
Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function | [1]Eyal Amiel, [2]Bart Everts, [3]Daniel Fritz, [4]Saritha Beauchamp, [5]Burong Ge, [6]Erika L Pearce, [7]Edward J Pearce [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.1302498 [ORCID] PubMed: 25108022 [ORCID]
| sirolimus [missing]; dendritic cell [missing]; lifetime [missing] | 2014-08-08 | |
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages | [1]Stanley Ching-Cheng Huang, [2]Bart Everts, [3]Yulia Ivanova, [4]David O'Sullivan, [5]Marcia Nascimento, [6]Amber M Smith, [7]Wandy Beatty, [8]Latisha Love-Gregory, [9]Wing Y Lam, [10]Christina M O'Neill, [11]Cong Yan, [12]Hong Du, [13]Nada A Abumrad, [14]Joseph F. Urban, [15]Maxim N Artyomov, [16]Erika L Pearce, [17]Edward J Pearce [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI.2956 [ORCID] PubMed: 25086775 [ORCID]
| macrophage [missing] | 2014-08-03 | Edward J Pearce (Q91529113; 5 items)
|
Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival | [1]Emmanuel L Gautier, [2]Stoyan Ivanov, [3]Jesse W Williams, [4]Stanley Ching-Cheng Huang, [5]Genevieve Marcelin, [6]Keke Fairfax, [7]Peter L Wang, [8]Jeremy S Francis, [9]Paola Leone, [10]David B Wilson, [11]Maxim N Artyomov, [12]Edward J Pearce, [13]Gwendalyn J. Randolph [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20140570 [ORCID] PubMed: 25024137 [ORCID]
| | 2014-07-14 | |
Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development | [1]David O'Sullivan, [2]Gerritje J W van der Windt, [3]Stanley Ching-Cheng Huang, [4]Jonathan D Curtis, [5]Chih-Hao Chang, [6]Michael D. Buck, [7]Jing Qiu, [8]Amber M Smith, [9]Wing Y Lam, [10]Lisa M DiPlato, [11]Fong-Fu Hsu, [12]Morris J. Birnbaum, [13]Edward J Pearce, [14]Erika L Pearce [Full author list] | Immunity [missing] | DOI: 10.1016/J.IMMUNI.2014.06.005 [ORCID] PubMed: 25001241 [ORCID]
| | 2014-07-04 | Edward J Pearce (Q91529113; 5 items)
|
Metabolic control of dendritic cell activation and function: recent advances and clinical implications | [1]Bart Everts, [2]Edward J Pearce [Full author list] | Frontiers in Immunology [missing] | DOI: 10.3389/FIMMU.2014.00203 [ORCID] PubMed: 24847328 [ORCID]
| dendritic cell [missing] | 2014-05-08 | |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation | [1]Bart Everts, [2]Eyal Amiel, [3]Stanley Ching-Cheng Huang, [4]Amber M Smith, [5]Chih-Hao Chang, [6]Wing Y Lam, [7]Veronika Redmann, [8]Tori C Freitas, [9]Julianna Blagih, [10]Gerritje J W van der Windt, [11]Maxim N Artyomov, [12]Russell G Jones, [13]Erika L Pearce, [14]Edward J Pearce [Full author list] | Nature Immunology [missing] | DOI: 10.1038/NI.2833 [ORCID] PubMed: 24562310 [ORCID]
| toll-like receptor [missing]; dendritic cell [missing] | 2014-02-23 | Edward J Pearce (Q91529113; 5 items)
|
Posttranscriptional control of T cell effector function by aerobic glycolysis | [1]Chih-Hao Chang, [2]Jonathan D Curtis, [3]Leonard B. Maggi, [4]Brandon Faubert, [5]Alejandro Villarino, [6]David O'Sullivan, [7]Stanley Ching-Cheng Huang, [8]Gerritje J W van der Windt, [9]Julianna Blagih, [10]Jing Qiu, [11]Jason D Weber, [12]Edward J Pearce, [13]Russell G Jones, [14]Erika L Pearce [Full author list] | Cell [missing] | DOI: 10.1016/J.CELL.2013.05.016 [ORCID] PubMed: 23746840 [ORCID]
| | 2013-06-01 | Edward J Pearce (Q91529113; 5 items)
|
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni | [1]Stanley Ching-Cheng Huang, [2]Tori C Freitas, [3]Eyal Amiel, [4]Bart Everts, [5]Erika L Pearce, [6]James B Lok, [7]Edward J Pearce [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.1002996 [ORCID] PubMed: 23133378 [ORCID]
| fatty acid [missing]; Schistosoma mansoni [missing] | 2012-10-25 | |
Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response | [1]Georgia Perona-Wright, [2]Jacob E Kohlmeier, [3]Elizabeth Bassity, [4]Tori C Freitas, [5]Katja Mohrs, [6]Tres Cookenham, [7]Haozhong Situ, [8]Edward J Pearce, [9]David L Woodland, [10]Markus Mohrs [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1119133109 [ORCID] PubMed: 23091017 [ORCID]
| | 2012-10-22 | |
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor | [1]Bart Everts, [2]Leonie Hussaarts, [3]Nicole N Driessen, [4]Moniek H J Meevissen, [5]Gabriele Schramm, [6]Alwin J van der Ham, [7]Barbara van der Hoeven, [8]Thomas Scholzen, [9]Sven Burgdorf, [10]Markus Mohrs, [11]Edward J Pearce, [12]Cornelis H Hokke, [13]Helmut Haas, [14]Hermelijn H Smits, [15]Maria Yazdanbakhsh [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20111381 [ORCID] PubMed: 22966004 [ORCID]
| | 2012-09-10 | |
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells | [1]Bart Everts, [2]Eyal Amiel, [3]Gerritje J W van der Windt, [4]Tori C Freitas, [5]Robert Chott, [6]Kevin Yarasheski, [7]Erika L Pearce, [8]Edward J Pearce [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2012-03-419747 [ORCID] PubMed: 22786879 [ORCID]
| inflammation [missing]; dendritic cell [missing] | 2012-07-11 | |
Cell death and reproductive regression in female Schistosoma mansoni | [1]Sarah E Galanti, [2]Stanley Ching-Cheng Huang, [3]Edward J Pearce [Full author list] | PLoS Neglected Tropical Diseases [missing] | DOI: 10.1371/JOURNAL.PNTD.0001509 [ORCID] PubMed: 22363825 [ORCID]
| Schistosoma mansoni [missing]; cell death [missing] | 2012-02-21 | |
IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease | [1]Keke C Fairfax, [2]Eyal Amiel, [3]Irah L King, [4]Tori C Freitas, [5]Markus Mohrs, [6]Edward J Pearce [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.1002490 [ORCID] PubMed: 22291593 [ORCID]
| schistosomiasis [missing]; Schistosoma mansoni [missing]; schistosomiasis mansoni [missing] | 2012-01-26 | |
Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover | [1]Mai H Tran, [2]Tori C Freitas, [3]Leanne Cooper, [4]Soraya Gaze, [5]Michelle L. Gatton, [6]Malcolm K Jones, [7]Erica Lovas, [8]Edward J Pearce, [9]Alex Loukas [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.1000840 [ORCID] PubMed: 20419145 [ORCID]
| Schistosoma mansoni [missing] | 2010-04-15 | |
Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation | [1]Connie M Krawczyk, [2]Thomas Holowka, [3]Jie Sun, [4]Julianna Blagih, [5]Eyal Amiel, [6]Ralph J DeBerardinis, [7]Justin R. Cross, [8]Euihye Jung, [9]Craig B. Thompson, [10]Russell G Jones, [11]Edward J Pearce [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2009-10-249540 [ORCID] PubMed: 20351312 [ORCID]
| toll-like receptor [missing]; dendritic cell [missing] | 2010-03-29 | |
T follicular helper cells differentiate from Th2 cells in response to helminth antigens | [1]Arielle Glatman Zaretsky, [2]Justin J Taylor, [3]Irah L King, [4]Fraser A Marshall, [5]Markus Mohrs, [6]Edward J Pearce [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20090303 [ORCID] PubMed: 19380637 [ORCID]
| | 2009-05-11 | |
A bone morphogenetic protein homologue in the parasitic flatworm, Schistosoma mansoni | [1]Tori C Freitas, [2]Euihye Jung, [3]Edward J Pearce [Full author list] | International Journal for Parasitology [missing] | DOI: 10.1016/J.IJPARA.2008.08.001 [ORCID] PubMed: 18765241 [ORCID]
| morphogenesis [missing]; Schistosoma mansoni [missing]; bone morphogenetic protein-like protein [missing] | 2008-08-15 | |
TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni | [1]Tori C Freitas, [2]Euihye Jung, [3]Edward J Pearce [Full author list] | PLOS Pathogens [missing] | DOI: 10.1371/JOURNAL.PPAT.0030052 [ORCID] PubMed: 17411340 [ORCID]
| Schistosoma mansoni [missing]; Inhibin/Activin, TGF-beta family, TGF-beta/Activin subfamily [missing] | 2007-04-01 | |
Th1 and Th2 cells help CD8 T-cell responses | [1]Melinda J Ekkens, [2]Devon J Shedlock, [3]Euihye Jung, [4]Amy Troy, [5]Erika L Pearce, [6]Hao Shen, [7]Edward J Pearce [Full author list] | Infection and Immunity [missing] | DOI: 10.1128/IAI.01328-06 [ORCID] PubMed: 17325050 [ORCID]
| | 2007-02-26 | |
Th2 response polarization during infection with the helminth parasite Schistosoma mansoni | [1]Edward J Pearce, [2]Colleen M Kane, [3]Jie Sun, [4]Justin J Taylor, [5]Amy S McKee, [6]Laura Cervi [Full author list] | Immunological Reviews [missing] | DOI: 10.1111/J.0105-2896.2004.00187.X [ORCID] PubMed: 15361236 [ORCID]
| Schistosoma mansoni [missing] | 2004-10-01 | |