| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor | [1]Zhengsheng Zhan, [2]Xia Peng, [3]Qiufeng Liu, [4]Fang Chen, [5]Yinchun Ji, [6]Shanyan Yao, [7]Yong Xi, [8]Yipeng Lin, [9]Tiantian Chen, [10]Yechun Xu, [11]Jing Ai, [12]Meiyu Geng, [13]Wenhu Duan [Full author list] | European Journal of Medicinal Chemistry [missing] | DOI: 10.1016/J.EJMECH.2016.03.076 [ORCID]
PubMed: 27061987 [ORCID]
| | 2016-06-30 | |
| Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities | [1]Ying Wang, [2]Zhengsheng Zhan, [3]Xifei Jiang, [4]Xia Peng, [5]Yanyan Shen, [6]Fang Chen, [7]Yinchun Ji, [8]Weiren Liu, [9]Yinghong Shi, [10]Wenhu Duan, [11]Jian Ding, [12]Jing Ai, [13]Meiyu Geng [Full author list] | Oncotarget [missing] | DOI: 10.18632/ONCOTARGET.9349 [ORCID]
PubMed: 27191264 [ORCID]
| | 2016-05-13 | |
| Discovery of Substituted 1H-Pyrazolo[3,4-b]pyridine Derivatives as Potent and Selective FGFR Kinase Inhibitors | [1]Bin Zhao, [2]Yixuan Li, [3]Pan Xu, [4]Yang Dai, [5]Cheng Luo, [6]Yiming Sun, [7]Jing Ai, [8]Meiyu Geng, [9]Wenhu Duan [Full author list] | ACS Medicinal Chemistry Letters [missing] | DOI: 10.1021/ACSMEDCHEMLETT.6B00066 [ORCID]
PubMed: 27326339 [ORCID]
| | 2016-04-20 | |
| Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors | [1]Tong-Chao Liu, [2]Xia Peng, [3]Yu-Chi Ma, [4]Yin-Chun Ji, [5]Dan-Qi Chen, [6]Mingyue Zheng, [7]Dong-Mei Zhao, [8]Mao-Sheng Cheng, [9]Mei-Yu Geng, [10]Jing-Kang Shen, [11]Jing Ai, [12]Bing Xiong [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2016.11 [ORCID]
PubMed: 27041462 [ORCID]
| | 2016-04-04 | |
| MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion | [1]Li-Hua Sun, [2]Mei-Ling Yan, [3]Xue-Ling Hu, [4]Li-Wei Peng, [5]Hui Che, [6]Ya-Nan Bao, [7]Fei Guo, [8]Tong Liu, [9]Xin Chen, [10]Rong Zhang, [11]Tao Ban, [12]Ning Wang, [13]Huai-Lei Liu, [14]Xu Hou, [15]Jing Ai [Full author list] | Molecular Neurodegeneration [missing] | DOI: 10.1186/S13024-015-0032-9 [ORCID]
PubMed: 26259688 [ORCID]
| microRNA [missing] | 2015-08-11 | Jing Ai (Q89993201; 3 items)
|
| Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold | [1]Jian Liu, [2]Xia Peng, [3]Yang Dai, [4]Wei Zhang, [5]Sumei Ren, [6]Jing Ai, [7]Meiyu Geng, [8]Yingxia Li [Full author list] | Organic and Biomolecular Chemistry [missing] | DOI: 10.1039/C5OB00778J [ORCID]
PubMed: 26080733 [ORCID]
| | 2015-07-28 | |
| Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis | [1]Weiqiang Xing, [2]Jing Ai, [3]Shiyu Jin, [4]Zhangxing Shi, [5]Xia Peng, [6]Lang Wang, [7]Yinchun Ji, [8]Dong Lu, [9]Yang Liu, [10]Meiyu Geng, [11]Youhong Hu [Full author list] | European Journal of Medicinal Chemistry [missing] | DOI: 10.1016/J.EJMECH.2015.03.041 [ORCID]
PubMed: 25827399 [ORCID]
| | 2015-03-21 | |
| Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors | [1]Chunpu Li, [2]Jing Ai, [3]Dengyou Zhang, [4]Xia Peng, [5]Xi Chen, [6]Zhiwei Gao, [7]Yi Su, [8]Wei Zhu, [9]Yinchun Ji, [10]Xiaoyan Chen, [11]Meiyu Geng, [12]Hong Liu [Full author list] | ACS Medicinal Chemistry Letters [missing] | DOI: 10.1021/ML5004876 [ORCID]
PubMed: 26005523 [ORCID]
| | 2015-03-02 | |
| MicroRNA-23a participates in estrogen deficiency induced gap junction remodeling of rats by targeting GJA1. | [1]Ning Wang, [2]Lu-Yao Sun, [3]Shou-Chen Zhang, [4]Ran Wei, [5]Fang Xie, [6]Jing Liu, [7]Yan Yan, [8]Ming-Jing Duan, [9]Lin-Lin Sun, [10]Ying-Hui Sun, [11]Hui-Fang Niu, [12]Rong Zhang, [13]Jing Ai [Full author list] | International Journal of Biological Sciences [missing] | DOI: 10.7150/IJBS.10930 [ORCID]
PubMed: 25798059 [ORCID]
| microRNA [missing]; hypoestrogenism [missing] | 2015-02-15 | Jing Ai (Q89993201; 3 items)
|
| Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity | [1]Zhengsheng Zhan, [2]Jing Ai, [3]Qiufeng Liu, [4]Yinchun Ji, [5]Tiantian Chen, [6]Yechun Xu, [7]Meiyu Geng, [8]Wenhu Duan [Full author list] | ACS Medicinal Chemistry Letters [missing] | DOI: 10.1021/ML500066M [ORCID]
PubMed: 24944742 [ORCID]
| organic chemistry [missing]; drug discovery [missing] | 2014-06-12 | |
| Design and synthesis of 3,3'-biscoumarin-based c-Met inhibitors | [1]Jimin Xu, [2]Jing Ai, [3]Sheng Liu, [4]Xia Peng, [5]Linqian Yu, [6]Meiyu Geng, [7]Fajun Nan [Full author list] | Organic and Biomolecular Chemistry [missing] | DOI: 10.1039/C4OB00364K [ORCID]
PubMed: 24781551 [ORCID]
| | 2014-04-30 | |
| Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities | [1]Zhiqing Liu, [2]Jing Ai, [3]Xia Peng, [4]Zilan Song, [5]Kui Wu, [6]Jing Zhang, [7]Qizheng Yao, [8]Yi Chen, [9]Yinchun Ji, [10]Yanhong Yang, [11]Meiyu Geng, [12]Ao Zhang [Full author list] | ACS Medicinal Chemistry Letters [missing] | DOI: 10.1021/ML400373J [ORCID]
PubMed: 24900831 [ORCID]
| | 2014-02-08 | |
| Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells | [1]Chang-xi He, [2]Jing Ai, [3]Wei-qiang Xing, [4]Yi Chen, [5]Hao-tian Zhang, [6]Min Huang, [7]You-hong Hu, [8]Jian Ding, [9]Mei-yu Geng [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2013.125 [ORCID]
PubMed: 24241352 [ORCID]
| | 2013-11-18 | |
| Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations | [1]Zhe Yu, [2]Yu-chi Ma, [3]Jing Ai, [4]Dan-qi Chen, [5]Dong-mei Zhao, [6]Xin Wang, [7]Yue-lei Chen, [8]Mei-yu Geng, [9]Bing Xiong, [10]Mao-sheng Cheng, [11]Jing-Kang Shen [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2013.85 [ORCID]
PubMed: 24056705 [ORCID]
| | 2013-09-23 | |
| Advance in research of microRNA in Caenorhabditis elegans | [1]Jing Liu, [2]Baofeng Yang, [3]Jing Ai [Full author list] | Journal of Cellular Biochemistry [missing] | DOI: 10.1002/JCB.24448 [ORCID]
PubMed: 23161250 [ORCID]
| Caenorhabditis elegans [missing] | 2013-05-01 | |
| Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway | [1]Zhongjie Liang, [2]Jing Ai, [3]Xiao Ding, [4]Xia Peng, [5]Dengyou Zhang, [6]Ruihan Zhang, [7]Ying Wang, [8]Fang Liu, [9]Mingyue Zheng, [10]Hualiang Jiang, [11]Hong Liu, [12]Meiyu Geng, [13]Cheng Luo [Full author list] | ACS Medicinal Chemistry Letters [missing] | DOI: 10.1021/ML4000047 [ORCID]
PubMed: 24900685 [ORCID]
| | 2013-02-25 | |
| MiR-106a is an independent prognostic marker in patients with glioblastoma | [1]Shiguang Zhao, [2]Guang Yang, [3]Yulong Mu, [4]Dayong Han, [5]Chen Shi, [6]Xin Chen, [7]Yifan Deng, [8]Daming Zhang, [9]Lu Wang, [10]Yaohua Liu, [11]Xu Hou, [12]Chunlei Wang, [13]Jianing Wu, [14]Huailei Liu, [15]Ligang Wang, [16]Guang Zhang, [17]Jiping Qi, [18]Xiang Fang, [19]Changbin Shi, [20]Jing Ai [Full author list] | Neuro-Oncology [missing] | DOI: 10.1093/NEUONC/NOT001 [ORCID]
PubMed: 23416698 [ORCID]
| | 2013-02-14 | |
| Gadd45α: a novel diabetes-associated gene potentially linking diabetic cardiomyopathy and baroreflex dysfunction | [1]Ning Wang, [2]Chao Yang, [3]Fang Xie, [4]Lihua Sun, [5]Xiaolin Su, [6]Ying Wang, [7]Ran Wei, [8]Rong Zhang, [9]Xia Li, [10]Baofeng Yang, [11]Jing Ai [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0049077 [ORCID]
PubMed: 23227140 [ORCID]
| diabetic cardiomyopathy [missing] | 2012-12-05 | |
| Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: synthesis and SAR study as tyrosine kinase c-Met inhibitors | [1]Kui Wu, [2]Jing Ai, [3]Qiufeng Liu, [4]TianTian Chen, [5]Ailing Zhao, [6]Xia Peng, [7]Yuanxiang Wang, [8]Yinchun Ji, [9]Qizheng Yao, [10]Yechun Xu, [11]Meiyu Geng, [12]Ao Zhang [Full author list] | Bioorganic & Medicinal Chemistry Letters [missing] | DOI: 10.1016/J.BMCL.2012.08.075 [ORCID]
PubMed: 22985853 [ORCID]
| | 2012-10-15 | |
| Daming capsule restores endothelial dysfunction induced by high-fat diet | [1]Rong Zhang, [2]Huifang Niu, [3]Ning Wang, [4]Lihua Sun, [5]Yi Xu, [6]Ruibo Zhao, [7]Xiang Ban, [8]Yao Yu, [9]Baofeng Yang, [10]Jing Ai [Full author list] | BMC Complementary and Alternative Medicine [missing] | DOI: 10.1186/1472-6882-12-21 [ORCID]
PubMed: 22443680 [ORCID]
| endothelium [missing] | 2012-03-24 | |
| Discovering potent inhibitors against c-Met kinase: molecular design, organic synthesis and bioassay | [1]Zhongjie Liang, [2]Xiao Ding, [3]Jing Ai, [4]Xiangqian Kong, [5]Limin Chen, [6]Liang Chen, [7]Cheng Luo, [8]Meiyu Geng, [9]Hong Liu, [10]Kaixian Chen, [11]Hualiang Jiang [Full author list] | Organic and Biomolecular Chemistry [missing] | DOI: 10.1039/C1OB06186K [ORCID]
PubMed: 22108637 [ORCID]
| molecular design [missing] | 2011-11-23 | |
| The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma | [1]Jing Ai, [2]Qingjuan Tang, [3]Yanlin Wu, [4]Yang Xu, [5]Teng Feng, [6]Ruiyu Zhou, [7]Yi Chen, [8]Xin Gao, [9]Qingfeng Zhu, [10]Xihua Yue, [11]Qiuming Pan, [12]Siyun Xu, [13]Jing Li, [14]Min Huang, [15]Jennifer Daugherty-Holtrop, [16]Yuanzheng He, [17]H Eric Xu, [18]Jia Fan, [19]Jian Ding, [20]Meiyu Geng [Full author list] | Journal of the National Cancer Institute [missing] | DOI: 10.1093/JNCI/DJR360 [ORCID]
PubMed: 22025622 [ORCID]
| inflammation [missing]; tumor metastasis [missing] | 2011-10-24 | |
| Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad | [1]Yan-lin Wu, [2]Jing Ai, [3]Jing-ming Zhao, [4]Bing Xiong, [5]Xiao-jie Xin, [6]Mei-yu Geng, [7]Xian-liang Xin, [8]Han-dong Jiang [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2011.2 [ORCID]
PubMed: 21499289 [ORCID]
| cell adhesion [missing] | 2011-04-18 | |
| Influence of fluvastatin on cardiac function and baroreflex sensitivity in diabetic rats | [1]Fang Xie, [2]Chao Sun, [3]Li-hua Sun, [4]Jing-yuan Li, [5]Xin Chen, [6]Hui Che, [7]Guan-yi Lu, [8]Bao-feng Yang, [9]Jing Ai [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2010.221 [ORCID]
PubMed: 21372824 [ORCID]
| | 2011-03-01 | |
| alpha2,6-hyposialylation of c-Met abolishes cell motility of ST6Gal-I-knockdown HCT116 cells | [1]Jin Qian, [2]Cai-Hua Zhu, [3]Shuai Tang, [4]Ai-Jun Shen, [5]Jing Ai, [6]Jing Li, [7]Mei-Yu Geng, [8]Jian Ding [Full author list] | Acta Pharmacologica Sinica [missing] | DOI: 10.1038/APS.2009.84 [ORCID]
PubMed: 19483716 [ORCID]
| | 2009-06-01 | |
| A triad of lys12, lys41, arg78 spatial domain, a novel identified heparin binding site on tat protein, facilitates tat-driven cell adhesion | [1]Jing Ai, [2]Xianliang Xin, [3]Mingyue Zheng, [4]Shuai Wang, [5]Shuying Peng, [6]Jing Li, [7]Limei Wang, [8]Hualiang Jiang, [9]Meiyu Geng [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0002662 [ORCID]
PubMed: 22423313 [ORCID]
| cell adhesion [missing]; heparin [missing] | 2008-07-16 | |