| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| Structural Analysis of Chemokine Receptor-Ligand Interactions | [1]Marta Arimont, [1-Q52117707]Marta Arimont, [2]Shan-Liang Sun, [3]Rob Leurs, [4]Martine Smit, [5]Iwan J P de Esch, [6]Chris de Graaf [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/ACS.JMEDCHEM.6B01309 [ORCID]
PubMed: 28165741 [ORCID]
| membrane protein [missing]; cell surface receptor [missing]; chemokine receptor family [missing]; physiological phenomenon [missing] | 2017-06-22 | Rob Leurs (Q88406954; 16 items)
|
| 3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine | [1]Ross McGuire, [2]Stefan Verhoeven, [3]Márton Vass, [4]Gerrit Vriend, [5]Iwan J P de Esch, [6]Scott J Lusher, [7]Rob Leurs, [8]Lars Ridder, [10]Tina Ritschel, [10-Q50730658]Tina Ritschel, [4-Q28874031]Gert Vriend, [6-Q50726826]Scott J Lusher, [8-Q50726884]Lars Ridder, [9]Albert Kooistra, [11]Chris de Graaf [Full author list] | Journal of Chemical Information and Modeling [missing] | DOI: 10.1021/ACS.JCIM.6B00686 [ORCID]
PubMed: 28125221 [ORCID]
| infrastructure [missing]; cheminformatics [missing]; research infrastructure [missing] | 2017-01-26 | Rob Leurs (Q88406954; 16 items)
|
| Identification of Ligand Binding Hot Spots of the Histamine H1 Receptor following Structure-Based Fragment Optimization | [1]Sebastiaan Kuhne, [2]Albert Kooistra, [3]Reggie Bosma, [4]Andrea Bortolato, [5]Maikel Wijtmans, [6]Henry F Vischer, [7]Jonathan S Mason, [8]Chris de Graaf, [9]Iwan J P de Esch, [10]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/ACS.JMEDCHEM.6B00981 [ORCID]
PubMed: 27643714 [ORCID]
| ligand binding [missing] | 2016-09-19 | Rob Leurs (Q88406954; 16 items)
|
| Function-specific virtual screening for GPCR ligands using a combined scoring method | [1]Albert Kooistra, [2]Henry F Vischer, [3]Daniel McNaught-Flores, [4]Rob Leurs, [5]Iwan J P de Esch, [6]Chris de Graaf [Full author list] | Scientific Reports [missing] | DOI: 10.1038/SREP28288 [ORCID]
PubMed: 27339552 [ORCID]
| G protein-coupled receptor [missing]; virtual screening [missing] | 2016-06-24 | Rob Leurs (Q88406954; 16 items)
|
| Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases | [1]Marco Siderius, [2]Anitha Shanmugham, [3]Paul England, [4]Tiffany van der Meer, [5]Jan Paul Bebelman, [6]Antoni R Blaazer, [7]Iwan J P de Esch, [8]Rob Leurs [Full author list] | Analytical Biochemistry [missing] | DOI: 10.1016/J.AB.2016.03.013 [ORCID]
PubMed: 27033007 [ORCID]
| biosensor [missing]; surface plasmon resonance [missing] | 2016-03-28 | Rob Leurs (Q88406954; 16 items)
|
| Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors | [1]Sabrina M de Munnik, [2]Martine J Smit, [3]Rob Leurs, [4]Henry F Vischer [Full author list] | Frontiers in Pharmacology [missing] | DOI: 10.3389/FPHAR.2015.00040 [ORCID]
PubMed: 25805993 [ORCID]
| G protein-coupled receptor [missing] | 2015-03-09 | Rob Leurs (Q88406954; 16 items)
|
| KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space | [1]Oscar P J van Linden, [2]Albert Kooistra, [3]Rob Leurs, [4]Iwan J P de Esch, [5]Chris de Graaf [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM400378W [ORCID]
PubMed: 23941661 [ORCID]
| database [missing] | 2013-09-20 | Rob Leurs (Q88406954; 16 items)
|
| Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure | [1]Chimed Jansen, [2]Huanchen Wang, [3]Albert Kooistra, [4]Chris de Graaf, [5]Kristina M Orrling, [6]Hermann Tenor, [7]Thomas Seebeck, [8]David Bailey, [9]Iwan J P de Esch, [10]Hengming Ke, [11]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM3017877 [ORCID]
PubMed: 23409953 [ORCID]
| Trypanosoma brucei [missing]; crystal structure [missing]; drug discovery [missing]; virtual screening [missing] | 2013-03-14 | Rob Leurs (Q88406954; 16 items)
|
| β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR | [1]Anne O Watts, [2]Folkert Verkaar, [3]Miranda M C van der Lee, [4]Claudia A W Timmerman, [5]Martien Kuijer, [6]Jody van Offenbeek, [7]Lambertus H C J van Lith, [8]Martine J Smit, [9]Rob Leurs, [10]Guido J R Zaman, [11]Henry F Vischer [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M112.406108 [ORCID]
PubMed: 23341447 [ORCID]
| cell biology [missing]; C-C motif chemokine ligand 21 [missing]; C-C motif chemokine ligand 19 [missing]; chemokine receptor activity [missing]; Arrestin beta 2 [missing]; C-C motif chemokine ligand 25 [missing]; Atypical chemokine receptor 4 [missing] | 2013-03-08 | Rob Leurs (Q88406954; 16 items)
|
| From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands | [1]Albert Kooistra, [2]Luc Roumen, [3]Rob Leurs, [4]Iwan J P de Esch, [5]Chris de Graaf [Full author list] | Methods in Enzymology [missing] | DOI: 10.1016/B978-0-12-407865-9.00015-7 [ORCID]
PubMed: 23374191 [ORCID]
| G protein-coupled receptor [missing]; virtual screening [missing] | 2013-01-01 | Rob Leurs (Q88406954; 16 items)
|
| Small and colorful stones make beautiful mosaics: fragment-based chemogenomics | [1]Chris de Graaf, [2]Henry F Vischer, [3]Gerdien E de Kloe, [4]Albert Kooistra, [5]Saskia Nijmeijer, [6]Martien Kuijer, [7]Mark H P Verheij, [8]Paul J England, [9]Jacqueline E van Muijlwijk-Koezen, [10]Rob Leurs, [11]Iwan J P de Esch [Full author list] | Drug Discovery Today [missing] | DOI: 10.1016/J.DRUDIS.2012.12.003 [ORCID]
PubMed: 23266367 [ORCID]
| | 2012-12-22 | Rob Leurs (Q88406954; 16 items)
|
| Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands | [1]Maikel Wijtmans, [2]Danny J Scholten, [3]Luc Roumen, [4]Meritxell Canals, [5]Hans Custers, [6]Marjolein Glas, [7]Marlies C A Vreeker, [8]Frans J J de Kanter, [9]Chris de Graaf, [10]Martine J Smit, [11]Iwan J P de Esch, [12]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM301240T [ORCID]
PubMed: 23150943 [ORCID]
| | 2012-11-14 | Rob Leurs (Q88406954; 16 items)
|
| Constitutive β-catenin signaling by the viral chemokine receptor US28 | [1]Ellen Langemeijer, [2]Erik Slinger, [3]Sabrina de Munnik, [4]Andreas Schreiber, [5]David Maussang, [6]Henry Vischer, [7]Folkert Verkaar, [8]Rob Leurs, [9]Marco Siderius, [10]Martine J Smit [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0048935 [ORCID]
PubMed: 23145028 [ORCID]
| | 2012-11-08 | Rob Leurs (Q88406954; 16 items)
|
| A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design | [1]Marijn P A Sanders, [2]Luc Roumen, [3]Eelke van der Horst, [4]J Robert Lane, [5]Henry F Vischer, [6]Jody van Offenbeek, [7]Henk de Vries, [8]Stefan Verhoeven, [9]Ken Y Chow, [10]Folkert Verkaar, [11]Margot W Beukers, [12]Ross McGuire, [13]Rob Leurs, [14]Adriaan P IJzerman, [15]Jacob de Vlieg, [16]Iwan J P de Esch, [17]Guido J R Zaman, [18]Jan P G Klomp, [19]Andreas Bender, [20]Chris de Graaf [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM300280E [ORCID]
PubMed: 22563707 [ORCID]
| G protein-coupled receptor [missing]; protein design [missing]; lessons learned [missing] | 2012-05-23 | Rob Leurs (Q88406954; 16 items)
|
| Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase | [1]Oscar P J van Linden, [2]Carine Farenc, [3]Willem H Zoutman, [4]Liesbeth Hameetman, [5]Maikel Wijtmans, [6]Rob Leurs, [7]Cornelis P Tensen, [8]Gregg Siegal, [9]Iwan J P de Esch [Full author list] | European Journal of Medicinal Chemistry [missing] | DOI: 10.1016/J.EJMECH.2011.11.020 [ORCID]
PubMed: 22137457 [ORCID]
| | 2012-01-01 | Rob Leurs (Q88406954; 16 items)
|
| Ubiquitination of CXCR7 controls receptor trafficking | [1]Meritxell Canals, [2]Danny J Scholten, [3]Sabrina de Munnik, [4]Mitchell K L Han, [5]Martine J Smit, [6]Rob Leurs [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0034192 [ORCID]
PubMed: 22457824 [ORCID]
| C-X-C motif chemokine ligand 12 [missing]; protein ubiquitination [missing]; positive regulation of receptor internalization [missing]; Arrestin beta 2 [missing]; Arrestin beta 1 [missing]; Atypical chemokine receptor 3 [missing] | 2012-01-01 | |
| Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor | [1]Chris de Graaf, [2]Albert Kooistra, [3]Henry F Vischer, [4]Vsevolod Katritch, [5]Martien Kuijer, [6]Mitsunori Shiroishi, [7]So Iwata, [8]Tatsuro Shimamura, [9]Raymond C Stevens, [10]Iwan J P de Esch, [11]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM2011589 [ORCID]
PubMed: 22007643 [ORCID]
| crystal structure [missing]; drug discovery [missing]; virtual screening [missing] | 2011-12-08 | Rob Leurs (Q88406954; 16 items)
|
| Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors | [1]Atilla Akdemir, [2]Prakash Rucktooa, [3]Aldo Jongejan, [4]Rene van Elk, [5]Sonia Bertrand, [6]Titia Sixma, [7]Daniel Bertrand, [8]August B Smit, [9]Rob Leurs, [10]Chris de Graaf, [11]Iwan J P de Esch [Full author list] | Bioorganic & Medicinal Chemistry [missing] | DOI: 10.1016/J.BMC.2011.08.028 [ORCID]
PubMed: 21920761 [ORCID]
| | 2011-10-15 | Rob Leurs (Q88406954; 16 items)
|
| Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A. | [1]Mark H P Verheij, [2]Chris de Graaf, [3]Gerdien E de Kloe, [4]Saskia Nijmeijer, [5]Henry F Vischer, [6]Rogier A Smits, [7]Obbe P Zuiderveld, [8]Saskia Hulscher, [9]Linda Silvestri, [10]Andrew J Thompson, [11]Jacqueline E van Muijlwijk-Koezen, [12]Sarah C R Lummis, [13]Rob Leurs, [14]Iwan J P de Esch [Full author list] | Bioorganic & Medicinal Chemistry Letters [missing] | DOI: 10.1016/J.BMCL.2011.06.123 [ORCID]
PubMed: 21782429 [ORCID]
| G protein-coupled receptor [missing] | 2011-07-02 | Rob Leurs (Q88406954; 16 items)
|
| Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis | [1]Ewald Edink, [2]Prakash Rucktooa, [3]Kim Retra, [4]Atilla Akdemir, [5]Tariq Nahar, [6]Obbe Zuiderveld, [7]René van Elk, [8]Elwin Janssen, [9]Pim van Nierop, [10]Jacqueline van Muijlwijk-Koezen, [11]August B Smit, [12]Titia Sixma, [13]Rob Leurs, [14]Iwan J P de Esch [Full author list] | Journal of the American Chemical Society [missing] | DOI: 10.1021/JA110571R [ORCID]
PubMed: 21322593 [ORCID]
| | 2011-02-15 | Rob Leurs (Q88406954; 16 items)
|
| CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells | [1]Sven Jähnichen, [2]Christophe Blanchetot, [3]David Maussang, [4]Maria Gonzalez-Pajuelo, [5]Ken Y Chow, [6]Leontien Bosch, [7]Sindi De Vrieze, [8]Benedikte Serruys, [9]Hans Ulrichts, [10]Wesly Vandevelde, [11]Michael Saunders, [12]Hans J De Haard, [13]Dominique Schols, [14]Rob Leurs, [15]Peter Vanlandschoot, [16]Theo Verrips, [17]Martine J Smit [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1012865107 [ORCID]
PubMed: 21059953 [ORCID]
| chemotaxis [missing] | 2010-11-08 | |
| The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice | [1]Gerold Bongers, [2]David Maussang, [3]Luciana R Muniz, [4]Vanessa M Noriega, [5]Alberto Fraile-Ramos, [6]Nick Barker, [7]Federica Marchesi, [8]Nanthakumar Thirunarayanan, [9]Henry F Vischer, [10]Lihui Qin, [11]Lloyd Mayer, [12]Noam Harpaz, [13]Rob Leurs, [14]Glaucia C Furtado, [15]Hans Clevers, [16]Domenico Tortorella, [17]Martine J Smit, [18]Sergio A Lira [Full author list] | Journal of Clinical Investigation [missing] | DOI: 10.1172/JCI42563 [ORCID]
PubMed: 20978345 [ORCID]
| Cytomegalovirus [missing] | 2010-11-01 | Rob Leurs (Q88406954; 16 items)
|
| Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands | [1]Gerdien E de Kloe, [2]Kim Retra, [3]Matthis Geitmann, [4]Per Källblad, [5]Tariq Nahar, [6]René van Elk, [7]August B Smit, [8]Jacqueline E van Muijlwijk-Koezen, [9]Rob Leurs, [10]Hubertus Irth, [11]Helena Danielson, [12]Iwan J P de Esch [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM100834Y [ORCID]
PubMed: 20828128 [ORCID]
| biosensor [missing]; surface plasmon resonance [missing] | 2010-10-01 | Rob Leurs (Q88406954; 16 items)
|
| The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning | [1]Saskia Nijmeijer, [2]Rob Leurs, [3]Martine J Smit, [4]Henry F Vischer [Full author list] | Journal of Biological Chemistry [missing] | DOI: 10.1074/JBC.M110.115618 [ORCID]
PubMed: 20622011 [ORCID]
| Epstein–Barr virus [missing]; G protein-coupled receptor [missing] | 2010-07-09 | Rob Leurs (Q88406954; 16 items)
|
| Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification | [1]Jeroen Kool, [2]Gerdien E de Kloe, [3]Ben Bruyneel, [4]Jon S de Vlieger, [5]Kim Retra, [6]Maikel Wijtmans, [7]Rene van Elk, [8]August B Smit, [9]Rob Leurs, [10]Henk Lingeman, [11]Iwan J P de Esch, [12]Hubertus Irth [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM100230K [ORCID]
PubMed: 20518527 [ORCID]
| | 2010-06-01 | Rob Leurs (Q88406954; 16 items)
|
| Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis | [1]Chris Ulens, [2]Atilla Akdemir, [3]Aldo Jongejan, [4]Rene van Elk, [5]Sonia Bertrand, [6]Anastassis Perrakis, [7]Rob Leurs, [8]August B Smit, [9]Titia Sixma, [10]Daniel Bertrand, [11]Iwan J P de Esch [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM801400G [ORCID]
PubMed: 19331415 [ORCID]
| pharmacology [missing]; acetylcholine [missing] | 2009-04-23 | Rob Leurs (Q88406954; 16 items)
|
| Transforming fragments into candidates: small becomes big in medicinal chemistry | [1]Gerdien E de Kloe, [2]David Bailey, [3]Rob Leurs, [4]Iwan J P de Esch [Full author list] | Drug Discovery Today [missing] | DOI: 10.1016/J.DRUDIS.2009.03.009 [ORCID]
PubMed: 19443265 [ORCID]
| | 2009-03-31 | |
| Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor | [1]Richard M van Rijn, [2]André van Marle, [3]Paul L Chazot, [4]Ellen Langemeijer, [5]Yongjun Qin, [6]Fiona C Shenton, [7]Herman D Lim, [8]Obbe P Zuiderveld, [9]Kamonchanok Sansuk, [10]Michel Dy, [11]Martine J Smit, [12]Cornelis P Tensen, [13]Remko A Bakker, [14]Rob Leurs [Full author list] | Biochemical Journal [missing] | DOI: 10.1042/BJ20071583 [ORCID]
PubMed: 18452403 [ORCID]
| | 2008-08-01 | |
| Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin | [1]Niels Hulsman, [2]Jan Paul Medema, [3]Carina Bos, [4]Aldo Jongejan, [5]Rob Leurs, [6]Martine J Smit, [7]Iwan J P de Esch, [8]Dick Richel, [9]Maikel Wijtmans [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM061371E [ORCID]
PubMed: 17441704 [ORCID]
| aspirin [missing] | 2007-05-17 | Rob Leurs (Q88406954; 16 items)
|
| Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation | [1]Gabriella Coruzzi, [2]Maristella Adami, [3]Elena Guaita, [4]Iwan J P de Esch, [5]Rob Leurs [Full author list] | European Journal of Pharmacology [missing] | DOI: 10.1016/J.EJPHAR.2007.02.026 [ORCID]
PubMed: 17382315 [ORCID]
| | 2007-02-23 | |
| Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist | [1]Herman D Lim, [2]Rogier A Smits, [3]Remko A Bakker, [4]Cindy M E van Dam, [5]Iwan J P de Esch, [6]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM060880D [ORCID]
PubMed: 17154494 [ORCID]
| | 2006-11-01 | Rob Leurs (Q88406954; 16 items)
|
| Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis | [1]David Maussang, [2]Dennis Verzijl, [3]Marijke van Walsum, [4]Rob Leurs, [5]Jens Holl, [6]Olivier Pleskoff, [7]Detlef Michel, [8]Guus A M S van Dongen, [9]Martine J Smit [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0604433103 [ORCID]
PubMed: 16924106 [ORCID]
| Cytomegalovirus [missing] | 2006-08-21 | |
| Keynote review: histamine H3 receptor antagonists reach out for the clinic | [1]Sylvain Celanire, [2]Maikel Wijtmans, [3]Patrice Talaga, [4]Rob Leurs, [5]Iwan J P de Esch [Full author list] | Drug Discovery Today [missing] | DOI: 10.1016/S1359-6446(05)03625-1 [ORCID]
PubMed: 16376822 [ORCID]
| | 2005-12-01 | Rob Leurs (Q88406954; 16 items)
|
| N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist | [1]Ruengwit Kitbunnadaj, [2]Takeshi Hashimoto, [3]Enzo Poli, [4]Obbe P Zuiderveld, [5]Alessandro Menozzi, [6]Ryoko Hidaka, [7]Iwan J P de Esch, [8]Remko A Bakker, [9]Wiro M P B Menge, [10]Atsushi Yamatodani, [11]Gabriella Coruzzi, [12]Henk Timmerman, [13]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM049475H [ORCID]
PubMed: 15771452 [ORCID]
| | 2005-03-01 | Rob Leurs (Q88406954; 16 items)
|
| The histamine H3 receptor: from gene cloning to H3 receptor drugs | [1]Rob Leurs, [2]Remko A Bakker, [3]Henk Timmerman, [4]Iwan J P de Esch [Full author list] | Nature Reviews Drug Discovery [missing] | DOI: 10.1038/NRD1631 [ORCID]
PubMed: 15665857 [ORCID]
| | 2005-02-01 | |
| Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H(3) receptor agonist | [1]Ruengwit Kitbunnadaj, [2]Obbe P Zuiderveld, [3]Bernard Christophe, [4]Saskia Hulscher, [5]Wiro M P B Menge, [6]Edith Gelens, [7]Erwin Snip, [8]Remko A Bakker, [9]Sylvain Celanire, [10]Michel Gillard, [11]Patrice Talaga, [12]Henk Timmerman, [13]Rob Leurs [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM049932U [ORCID]
PubMed: 15115383 [ORCID]
| | 2004-05-01 | |
| A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine | [1]Takeshi Hashimoto, [2]Shinya Harusawa, [3]Lisa Araki, [4]Obbe P Zuiderveld, [5]Martine J Smit, [6]Tomonari Imazu, [7]Seiichiroh Takashima, [8]Yumiko Yamamoto, [9]Yasuhiko Sakamoto, [10]Takushi Kurihara, [11]Rob Leurs, [12]Remko A Bakker, [13]Atsushi Yamatodani [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM0300025 [ORCID]
PubMed: 12825954 [ORCID]
| | 2003-07-01 | Rob Leurs (Q88406954; 16 items)
|
| The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion | [1]Yvonne K Gruijthuijsen, [2]Paola Casarosa, [3]Suzanne Kaptein, [4]Jos L V Broers, [5]Rob Leurs, [6]Cathrien A Bruggeman, [7]Martine J Smit, [8]Cornelis Vink [Full author list] | Journal of Virology [missing] | DOI: 10.1128/JVI.76.3.1328-1338.2002 [ORCID]
PubMed: 11773407 [ORCID]
| Cytomegalovirus [missing]; G protein-coupled receptor [missing] | 2002-02-01 | |