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50 publications found

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Group #1

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine[1]Martilias S Farrell, [2]John D McCorvy, [3]Xi-Ping Huang, [4]Daniel J Urban, [5]Kate L White, [6]Patrick M Giguere, [7]Allison K Doak, [8]Alison I Bernstein, [9]Kristen A Stout, [10]Su Mi Park, ..., [20]William E Fantegrossi, [21]William C Wetsel, [22]Bryan L Roth [Full author list]PLOS One [missing]DOI: 10.1371/JOURNAL.PONE.0150602 [ORCID]
PubMed: 26963248 [ORCID]
2016-03-10Bryan L. Roth (Q89688393; 44 items)
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65[1]Xi-Ping Huang, [2]Joel Karpiak, [3]Wesley K Kroeze, [4]Hu Zhu, [5]Xin Chen, [6]Sheryl S Moy, [7]Kara A Saddoris, [8]Viktoriya D Nikolova, [9]Martilias S Farrell, [10]Sheng Wang, [11]Thomas J Mangano, [12]Deepak A Deshpande, [13]Alice Jiang, [14]Raymond B Penn, [15]Jian Jin, [16]Beverly H Koller, [17]Terry Kenakin, [18]Brian K Shoichet, [19]Bryan L Roth [Full author list]Nature [missing]DOI: 10.1038/NATURE15699 [ORCID]
PubMed: 26550826 [ORCID]
pharmacology [missing]2015-11-09Bryan L. Roth (Q89688393; 44 items)
Novel molecular targets of dezocine and their clinical implications[1]Renyu Liu, [2]Xi-Ping Huang, [3]Alexei Yeliseev, [4]Jin Xi, [5]Bryan L Roth [Full author list]Anesthesiology [missing]DOI: 10.1097/ALN.0000000000000076 [ORCID]
PubMed: 24263237 [ORCID]
pain [missing]; anaesthesiology [missing]2014-03-01Bryan L. Roth (Q89688393; 44 items)
Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory[1]Hu Zhu, [2]Kristen E Pleil, [3]Daniel J Urban, [4]Sheryl S Moy, [5]Thomas L Kash, [6]Bryan L Roth [Full author list]Neuropsychopharmacology [missing]DOI: 10.1038/NPP.2014.35 [ORCID]
PubMed: 24525710 [ORCID]
fear memory [missing]2014-02-14Bryan L. Roth (Q89688393; 44 items)
The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor[1]Bryan L Roth, [2]Simon Gibbons, [3]Warunya Arunotayanun, [4]Xi-Ping Huang, [5]Vincent Setola, [6]Ric Treble, [7]Les Iversen [Full author list]PLOS One [missing]DOI: 10.1371/JOURNAL.PONE.0059334 [ORCID]
PubMed: 23527166 [ORCID]
2013-01-01Bryan L. Roth (Q89688393; 44 items)
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels[1]Michael J Twiner, [2]Gregory J Doucette, [3]Andrew Rasky, [4]Xi-Ping Huang, [5]Bryan L Roth, [6]Michael C Sanguinetti [Full author list]Chemical Research in Toxicology [missing]DOI: 10.1021/TX300283T [ORCID]
PubMed: 22856456 [ORCID]
2012-08-10Bryan L. Roth (Q89688393; 44 items)
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons[1]Hsien-Sung Huang, [2]John A Allen, [3]Angela M Mabb, [4]Ian F King, [5]Jayalakshmi Miriyala, [6]Bonnie Taylor-Blake, [7]Noah Sciaky, [8]J Walter Dutton, [9]Hyeong-Min Lee, [10]Xin Chen, [11]Jian Jin, [12]Arlene S Bridges, [13]Mark J. Zylka, [14]Bryan L Roth, [15]Benjamin D Philpot [Full author list]Nature [missing]DOI: 10.1038/NATURE10726 [ORCID]
PubMed: 22190039 [ORCID]
topotecan [missing]2012-01-12Bryan L. Roth (Q89688393; 44 items)
Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment[1]Xi-Ping Huang, [2]Vincent Setola, [3]Prem N Yadav, [4]John A Allen, [5]Sarah C Rogan, [6]Bonnie J Hanson, [7]Chetana Revankar, [8]Matt Robers, [9]Chris Doucette, [10]Bryan L Roth [Full author list]Molecular Pharmacology [missing]DOI: 10.1124/MOL.109.058057 [ORCID]
PubMed: 19570945 [ORCID]
2009-10-01Bryan L. Roth (Q89688393; 44 items)
Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo[1]Atheir I Abbas, [2]Peter B Hedlund, [3]Xi-Ping Huang, [4]Thuy B Tran, [5]Herbert Y. Meltzer, [6]Bryan L Roth, [6-Q89688393]Bryan L. Roth [Full author list]Psychopharmacology [missing]DOI: 10.1007/S00213-009-1521-8 [ORCID]
PubMed: 19337725 [ORCID]
2009-07-01Bryan L. Roth (Q89688393; 44 items)
Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors[1]Georgia M Alexander, [2]Sarah C Rogan, [3]Atheir I Abbas, [4]Blaine N Armbruster, [5]Ying Pei, [6]John A Allen, [7]Randal J Nonneman, [8]John Hartmann, [9]Sheryl S Moy, [10]Miguel A Nicolelis, [11]James O McNamara, [12]Bryan L Roth [Full author list]Neuron [missing]DOI: 10.1016/J.NEURON.2009.06.014 [ORCID]
PubMed: 19607790 [ORCID]
G protein-coupled receptor [missing]2009-07-01Bryan L. Roth (Q89688393; 44 items)

Group #2

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil[1]Dorota Zolkowska, [2]Raka Jain, [3]Richard B. Rothman, [4]John S Partilla, [5]Bryan L Roth, [6]Vincent Setola, [7]Thomas E Prisinzano, [8]Michael H Baumann [Full author list]Journal of Pharmacology and Experimental Therapeutics [missing]DOI: 10.1124/JPET.108.146142 [ORCID]
PubMed: 19197004 [ORCID]
dopamine [missing]; modafinil [missing]2009-02-05Bryan L. Roth (Q89688393; 44 items)
p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling[1]Douglas J Sheffler, [2]Wesley K Kroeze, [3]Bonnie G Garcia, [4]Ariel Y Deutch, [5]Sandra J Hufeisen, [6]Patrick Leahy, [7]Jens C Brüning, [8]Bryan L Roth [Full author list]Proceedings of the National Academy of Sciences of the United States of America [missing]DOI: 10.1073/PNAS.0600585103 [ORCID]
PubMed: 16537434 [ORCID]
G protein-coupled receptor [missing]; Ribosomal protein S6 kinase polypeptide 3 [missing]2006-03-10Bryan L. Roth (Q89688393; 44 items)
Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor[1]Vincent Setola, [2]Malgorzata Dukat, [3]Richard A Glennon, [4]Bryan L Roth [Full author list]Molecular Pharmacology [missing]DOI: 10.1124/MOL.104.009266 [ORCID]
PubMed: 15831837 [ORCID]
5-hydroxytryptamine receptor 2A [missing]; 5-hydroxytryptamine receptor 2B [missing]; serotonin binding [missing]; 5-hydroxytryptamine receptor 2C [missing]2005-07-01
Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration[1]Richard B. Rothman, [2]Bruce E Blough, [3]William L Woolverton, [4]Karen G Anderson, [5]S Stevens Negus, [6]Nancy K Mello, [7]Bryan L Roth, [8]Michael H Baumann [Full author list]Journal of Pharmacology and Experimental Therapeutics [missing]DOI: 10.1124/JPET.104.082503 [ORCID]
PubMed: 15761112 [ORCID]
cocaine [missing]2005-06-01
The human polyomavirus, JCV, uses serotonin receptors to infect cells[1]Gwendolyn F Elphick, [2]William Querbes, [3]Joslynn A Jordan, [4]Gretchen V Gee, [5]Sylvia Eash, [6]Kate Manley, [7]Aisling Dugan, [8]Megan Stanifer, [9]Anushree Bhatnagar, [10]Wesley K Kroeze, [11]Bryan L Roth, [12]Walter J Atwood [Full author list]Science [missing]DOI: 10.1126/SCIENCE.1103492 [ORCID]
PubMed: 15550673 [ORCID]
serotonin [missing]; Human polyomavirus [missing]2004-11-19Bryan L. Roth (Q89688393; 44 items)
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors[1]Anushree Bhatnagar, [2]Douglas J Sheffler, [3]Wesley K Kroeze, [4]BethAnn Compton-Toth, [5]Bryan L Roth [Full author list]Journal of Biological Chemistry [missing]DOI: 10.1074/JBC.M404673200 [ORCID]
PubMed: 15190056 [ORCID]
serotonin [missing]2004-08-13Bryan L. Roth (Q89688393; 44 items)
Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia[1]Bryan L Roth, [2]Douglas J Sheffler, [3]Wesley K Kroeze [Full author list]Nature Reviews Drug Discovery [missing]DOI: 10.1038/NRD1346 [ORCID]
PubMed: 15060530 [ORCID]
schizophrenia [missing]; mood disorder [missing]2004-04-01Bryan L. Roth (Q89688393; 44 items)
3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro[1]Vincent Setola, [2]Sandra J Hufeisen, [3]Jane Grande-Allen, [4]Ivan Vesely, [5]Richard A Glennon, [6]Bruce Blough, [7]Richard B. Rothman, [8]Bryan L Roth [Full author list]Molecular Pharmacology [missing]DOI: 10.1124/MOL.63.6.1223 [ORCID]
PubMed: 12761331 [ORCID]
2003-06-01Bryan L. Roth (Q89688393; 44 items)
Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist[1]Bryan L Roth, [2]Karen Baner, [3]Richard Westkaemper, [4]Daniel Siebert, [5]Kenner C Rice, [6]SeAnna Steinberg, [7]Paul Ernsberger, [8]Richard B. Rothman [Full author list]Proceedings of the National Academy of Sciences of the United States of America [missing]DOI: 10.1073/PNAS.182234399 [ORCID]
PubMed: 12192085 [ORCID]
opioid [missing]2002-08-21Bryan L. Roth (Q89688393; 44 items)

Group #3

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds[1]Giancarlo Bruni, [2]Andrew J. Rennekamp, [3]Andrea Velenich, [4]Matthew McCarroll, [5]Leo Gendelev, [6]Ethan Fertsch, [7]Jack Taylor, [8]Parth Lakhani, [9]Dennis Lensen, [10]Tama Evron, [11]Paul J Lorello, [12]Xi-Ping Huang, [13]Sabine Kolczewski, [14]Galen Carey, [15]Barbara J Caldarone, [16]Eric Prinssen, [17]Bryan L Roth, [18]Michael J Keiser, [19]Randall T Peterson, [20]David Kokel [Full author list]Nature Chemical Biology [missing]DOI: 10.1038/NCHEMBIO.2097 [ORCID]
PubMed: 27239787 [ORCID]
Danio rerio [missing]2016-05-30Bryan L. Roth (Q89688393; 44 items)
Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides[1]Eyal Vardy, [2]Maria F Sassano, [3]Andrew J. Rennekamp, [4]Wesley K Kroeze, [5]Philip D Mosier, [6]Richard B Westkaemper, [7]Craig W Stevens, [8]Vsevolod Katritch, [9]Raymond C Stevens, [10]Randall T Peterson, [11]Bryan L Roth [Full author list]Chemistry and Biology [missing]DOI: 10.1016/J.CHEMBIOL.2015.05.012 [ORCID]
PubMed: 26091169 [ORCID]
opioid [missing]; clinical chemistry [missing]; drug discovery [missing]2015-06-01Bryan L. Roth (Q89688393; 44 items)
In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding[1]George A Lemieux, [2]Michael J Keiser, [3]Maria F Sassano, [4]Christian Laggner, [5]Fahima Mayer, [6]Roland J Bainton, [7]Zena Werb, [8]Bryan L Roth, [9]Brian K. Shoichet, [10]Kaveh Ashrafi [Full author list]PLOS Biology [missing]DOI: 10.1371/JOURNAL.PBIO.1001712 [ORCID]
PubMed: 24260022 [ORCID]
Caenorhabditis elegans [missing]; pharmacology [missing]2013-11-01Bryan L. Roth (Q89688393; 44 items)
The presynaptic component of the serotonergic system is required for clozapine's efficacy[1]Prem N Yadav, [2]Atheir I Abbas, [3]Martilias S Farrell, [4]Vincent Setola, [5]Noah Sciaky, [6]Xi-Ping Huang, [7]Wesley K Kroeze, [8]LaTasha K Crawford, [9]David A Piel, [10]Michael J Keiser, [11]John J Irwin, [12]Brian K Shoichet, [13]Evan S Deneris, [14]Jay Gingrich, [15]Sheryl G Beck, [16]Bryan L Roth [Full author list]Neuropsychopharmacology [missing]DOI: 10.1038/NPP.2010.195 [ORCID]
PubMed: 21048700 [ORCID]
2010-11-03Bryan L. Roth (Q89688393; 44 items)
9-Aminomethyl-9,10-dihydroanthracene (AMDA) analogs as structural probes for steric tolerance in 5-HT2A and H1 receptor binding sites[1]Jitesh R Shah, [2]Philip D Mosier, [3]Srinivas Peddi, [4]Bryan L Roth, [5]Richard B Westkaemper [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2009.12.064 [ORCID]
PubMed: 20045641 [ORCID]
organic chemistry [missing]; drug discovery [missing]2010-02-01
Predicting new molecular targets for known drugs[1]Michael J Keiser, [2]Vincent Setola, [3]John J Irwin, [4]Christian Laggner, [5]Atheir I Abbas, [6]Sandra J Hufeisen, [7]Niels H Jensen, [8]Michael B Kuijer, [9]Roberto C Matos, [10]Thuy B Tran, [11]Ryan Whaley, [12]Richard A Glennon, [13]Jérôme Hert, [14]Kelan Thomas, [15]Douglas D Edwards, [16]Brian K. Shoichet, [17]Bryan L Roth [Full author list]Nature [missing]DOI: 10.1038/NATURE08506 [ORCID]
PubMed: 19881490 [ORCID]
2009-11-01Bryan L. Roth (Q89688393; 44 items)
Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation[1]Scott P Runyon, [2]Philip D Mosier, [3]Bryan L Roth, [4]Richard A Glennon, [5]Richard B Westkaemper [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM800771X [ORCID]
PubMed: 18847250 [ORCID]
drug discovery [missing]2008-11-13
Methoxy-substituted 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives exhibit differential binding affinities at the 5-HT(2A) receptor[1]Gajanan K Dewkar, [2]Srinivas Peddi, [3]Philip D Mosier, [4]Bryan L Roth, [5]Richard B Westkaemper [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2008.08.059 [ORCID]
PubMed: 18774714 [ORCID]
organic chemistry [missing]; drug discovery [missing]2008-10-01
Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors[1]Donald Sikazwe, [2]Mikhail L Bondarev, [3]Małgorzata Dukat, [4]Jagadeesh B Rangisetty, [5]Bryan L Roth, [6]Richard A Glennon [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM060469Q [ORCID]
PubMed: 16913710 [ORCID]
serotonin [missing]2006-08-24
1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands[1]Mase Lee, [2]Jagadeesh B Rangisetty, [3]Manik R Pullagurla, [4]Małgorzata Dukat, [5]Vince Setola, [6]Bryan L Roth, [7]Richard A Glennon [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2005.01.031 [ORCID]
PubMed: 15745826 [ORCID]
serotonin [missing]2005-03-15
Spiro[9,10-dihydroanthracene]-9,3'-pyrrolidine-a structurally unique tetracyclic 5-HT2A receptor antagonist[1]Srinivas Peddi, [2]Bryan L Roth, [3]Richard A Glennon, [4]Richard B Westkaemper [Full author list]European Journal of Pharmacology [missing]DOI: 10.1016/J.EJPHAR.2003.09.059 [ORCID]
PubMed: 14660041 [ORCID]
2003-12-15

Group #4

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo[1]Kate L White, [2]J Elliott Robinson, [3]Hu Zhu, [4]Jeffrey F DiBerto, [5]Prabhakar R Polepally, [6]Jordan Zjawiony, [7]David E Nichols, [8]C J Malanga, [9]Bryan L Roth [Full author list]Journal of Pharmacology and Experimental Therapeutics [missing]DOI: 10.1124/JPET.114.216820 [ORCID]
PubMed: 25320048 [ORCID]
opioid [missing]; bias [missing]2014-10-15Bryan L. Roth (Q89688393; 44 items)
Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor[1]Feng Yan, [2]Ruslan V Bikbulatov, [3]Viorel Mocanu, [4]Nedyalka Dicheva, [5]Carol E Parker, [6]William C Wetsel, [7]Philip D Mosier, [8]Richard B Westkaemper, [9]John A Allen, [10]Jordan Zjawiony, [11]Bryan L Roth [Full author list]Biochemistry [missing]DOI: 10.1021/BI900605N [ORCID]
PubMed: 19555087 [ORCID]
biochemistry [missing]; pharmacology [missing]; opioid [missing]; active state [missing]2009-07-01Bryan L. Roth (Q89688393; 44 items)
Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist[1]Thomas A. Munro, [2]Mark A Rizzacasa, [3]Bryan L Roth, [4]Beth A Toth, [5]Feng Yan [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM049438Q [ORCID]
PubMed: 15658846 [ORCID]
opioid [missing]; drug discovery [missing]2005-01-01
Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations[1]Charles Chavkin, [2]Sumit Sud, [3]Wenzhen Jin, [4]Jeremy Stewart, [5]Jordan Zjawiony, [6]Daniel J Siebert, [7]Beth Ann Toth, [8]Sandra J Hufeisen, [9]Bryan L Roth [Full author list]Journal of Pharmacology and Experimental Therapeutics [missing]DOI: 10.1124/JPET.103.059394 [ORCID]
PubMed: 14718611 [ORCID]
Salvia divinorum [missing]; opioid [missing]2004-01-08Bryan L. Roth (Q89688393; 44 items)

Group #5

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Structure-based discovery of opioid analgesics with reduced side effects[1]Aashish Manglik, [2]Henry Lin, [3]Dipendra K Aryal, [4]John D McCorvy, [5]Daniela Dengler, [6]Gregory Corder, [7]Anat Levit, [8]Ralf C Kling, [9]Viachaslau Bernat, [10]Harald Hübner, [11]Xi-Ping Huang, [12]Maria F Sassano, [13]Patrick M Giguère, [14]Stefan Löber, [15]Da Duan, [16]Gregory Scherrer, [17]Brian Kobilka, [18]Peter Gmeiner, [19]Bryan L Roth, [20]Brian K Shoichet [Full author list]Nature [missing]DOI: 10.1038/NATURE19112 [ORCID]
PubMed: 27533032 [ORCID]
opioid [missing]2016-08-17Bryan L. Roth (Q89688393; 44 items)
Functional selectivity and classical concepts of quantitative pharmacology[1]Jonathan D Urban, [2]William P Clarke, [3]Mark von Zastrow, [4]David E Nichols, [5]Brian Kobilka, [6]Harel Weinstein, [7]Jonathan Javitch, [8]Bryan L Roth, [9]Arthur Christopoulos, [10]Patrick M. Sexton, [11]Keith J Miller, [12]Michael Spedding, [13]Richard Mailman [Full author list]Journal of Pharmacology and Experimental Therapeutics [missing]DOI: 10.1124/JPET.106.104463 [ORCID]
PubMed: 16803859 [ORCID]
pharmacology [missing]2006-06-27Bryan L. Roth (Q89688393; 44 items)

Group #6

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1[1]Jacob I Stuckey, [2]Bradley M Dickson, [3]Nancy Cheng, [4]Yanli Liu, [5]Jacqueline L Norris, [6]Stephanie H Cholensky, [7]Wolfram Tempel, [8]Su Qin, [9]Katherine G Huber, [10]Cari Sagum, ..., [12]Fengling Li, [13]Xi-Ping Huang, [14]Bryan L Roth, [15]Brandi M Baughman, [16]Guillermo Senisterra, ... [Full author list]Nature Chemical Biology [missing]DOI: 10.1038/NCHEMBIO.2007 [ORCID]
PubMed: 26807715 [ORCID]
2016-01-25Bryan L. Roth (Q89688393; 44 items)
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells[1]Masoud Vedadi, [2]Dalia Barsyte-Lovejoy, [3]Feng Liu, [4]Sylvie Rival-Gervier, [5]Abdellah Allali-Hassani, [6]Viviane Labrie, [7]Tim J Wigle, [8]Peter A. DiMaggio, [9]Gregory A Wasney, [10]Alena Siarheyeva, ..., [22]Ashutosh Tripathy, [23]Aled Edwards, [24]Bryan L Roth, [25]William P Janzen, [26]Benjamin A Garcia, ... [Full author list]Nature Chemical Biology [missing]DOI: 10.1038/NCHEMBIO.599 [ORCID]
PubMed: 21743462 [ORCID]
cell biology [missing]2011-08-01Bryan L. Roth (Q89688393; 44 items)

Group #7

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors[1]John D Chan, [2]John D McCorvy, [3]Sreemoyee Acharya, [4]Malcolm E Johns, [5]Tim A. Day, [6]Bryan L Roth, [7]Jonathan S Marchant [Full author list]PLOS Pathogens [missing]DOI: 10.1371/JOURNAL.PPAT.1005651 [ORCID]
PubMed: 27187180 [ORCID]
G protein-coupled receptor [missing]; Schistosoma mansoni [missing]2016-05-17Bryan L. Roth (Q89688393; 44 items)
Structure and function of serotonin G protein-coupled receptors.[1]John D McCorvy, [2]Bryan L Roth [Full author list]Pharmacology & Therapeutics [missing]DOI: 10.1016/J.PHARMTHERA.2015.01.009 [ORCID]
PubMed: 25601315 [ORCID]
G protein-coupled receptor [missing]; serotonin [missing]2015-01-17Bryan L. Roth (Q89688393; 44 items)

Misc

Matched potential author: Bryan L. Roth - author of 44 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
DREADDs: novel tools for drug discovery and development[1]Hyeong-Min Lee, [2]Patrick M Giguere, [3]Bryan L Roth [Full author list]Drug Discovery Today [missing]DOI: 10.1016/J.DRUDIS.2013.10.018 [ORCID]
PubMed: 24184433 [ORCID]
drug discovery [missing]2013-11-01
Pharmacosynthetics: Reimagining the pharmacogenetic approach[1]Martilias S Farrell, [2]Bryan L Roth [Full author list]Brain Research [missing]DOI: 10.1016/J.BRAINRES.2012.09.043 [ORCID]
PubMed: 23063887 [ORCID]
2013-05-20
Securinine, a myeloid differentiation agent with therapeutic potential for AML[1]Kalpana Gupta, [2]Amitabha Chakrabarti, [3]Sonia Rana, [4]Ritu Ramdeo, [5]Bryan L Roth, [6]Munna L Agarwal, [7]William Tse, [8]Mukesh K Agarwal, [9]David N Wald [Full author list]PLOS One [missing]DOI: 10.1371/JOURNAL.PONE.0021203 [ORCID]
PubMed: 21731671 [ORCID]
2011-01-01
HTS and rational drug design to generate a class of 5-HT(2C)-selective ligands for possible use in schizophrenia[1]Alan P Kozikowski, [2]Sung Jin Cho, [3]Niels H Jensen, [4]John A Allen, [5]Andreas M Svennebring, [6]Bryan L Roth [Full author list]ChemMedChem [missing]DOI: 10.1002/CMDC.201000186 [ORCID]
PubMed: 20533502 [ORCID]
schizophrenia [missing]2010-08-01Bryan L. Roth (Q89688393; 44 items)
Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders[1]Atheir Abbas, [2]Bryan L Roth [Full author list]Expert Opinion on Pharmacotherapy [missing]DOI: 10.1517/14656560802532707 [ORCID]
PubMed: 19040345 [ORCID]
tartrate [missing]; pimavanserin [missing]; pimavanserin tartrate [missing]2008-12-01
Engineering GPCR signaling pathways with RASSLs[1]Bruce R Conklin, [2]Edward C Hsiao, [3]Sylvie Claeysen, [4]Aline Dumuis, [5]Supriya Srinivasan, [6]John R Forsayeth, [7]Jean-Marc Guettier, [8]W C Chang, [9]Ying Pei, [10]Ken D McCarthy, [11]Robert A Nissenson, [12]Jürgen Wess, [13]Joël Bockaert, [14]Bryan L Roth [Full author list]Nature Methods [missing]DOI: 10.1038/NMETH.1232 [ORCID]
PubMed: 18668035 [ORCID]
cell biology [missing]; G protein-coupled receptor [missing]2008-08-01
Arresting serotonin[1]Atheir Abbas, [2]Bryan L Roth [Full author list]Proceedings of the National Academy of Sciences of the United States of America [missing]DOI: 10.1073/PNAS.0711335105 [ORCID]
PubMed: 18195368 [ORCID]
serotonin [missing]2008-01-22
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand[1]Blaine N Armbruster, [2]Xiang Li, [3]Mark H Pausch, [4]Stefan Herlitze, [5]Bryan L Roth [Full author list]Proceedings of the National Academy of Sciences of the United States of America [missing]DOI: 10.1073/PNAS.0700293104 [ORCID]
PubMed: 17360345 [ORCID]
G protein-coupled receptor [missing]2007-03-20
Drugs and valvular heart disease[1]Bryan L Roth [Full author list]The New England Journal of Medicine [missing]DOI: 10.1056/NEJMP068265 [ORCID]
PubMed: 17202450 [ORCID]
heart disease [missing]2007-01-04
WAY-100635 is a potent dopamine D4 receptor agonist[1]Benjamin R Chemel, [2]Bryan L Roth, [3]Blaine Armbruster, [4]Val J Watts, [5]David E Nichols [Full author list]Psychopharmacology [missing]DOI: 10.1007/S00213-006-0490-4 [ORCID]
PubMed: 16915381 [ORCID]
dopamine [missing]2006-10-01

Potential author items

NameDescriptionAuthored itemsIdentifiersEmployer(s)
Bryan L. RothAmerican pharmacologist44ORCID: 0000-0002-0561-6520
ISNI: 0000000055596359
VIAF ID: 75400848
Bryan RothAmerican businessman0
Bryan Rothcollege basketball player (1984–1985) Akron0University of Akron [missing]
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