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10 publications found

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Group #1

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors[1]Timothy Forsyth, [2]Patrick C Kearney, [3]Byung Gyu Kim, [4]Henry W B Johnson, [5]Naing Aay, [6]Arlyn Arcalas, [7]David S Brown, [8]Vicky Chan, [9]Jeff Chen, [10]Hongwang Du, ..., [14]Mohamed A Ibrahim, [15]Brian Kane, [16]Elena S Koltun, [17]Grace Mann, [18]Lisa E Meyr, ... [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2012.10.007 [ORCID]
PubMed: 23127890 [ORCID]
2012-12-15
Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)[1]Kenneth D Rice, [2]Naing Aay, [3]Neel K Anand, [4]Charles M Blazey, [5]Owen J Bowles, [6]Joerg Bussenius, [7]Simona Costanzo, [8]Jeffry K Curtis, [9]Steven C Defina, [10]Larisa Dubenko, ..., [13]Abigail R Kennedy, [14]Angie I Kim, [15]Elena S Koltun, [16]Julie C Lougheed, [17]Jean-Claire L Manalo, ... [Full author list]ACS Medicinal Chemistry Letters [missing]DOI: 10.1021/ML300049D [ORCID]
PubMed: 24900486 [ORCID]
organic chemistry [missing]; drug discovery [missing]; allosteric inhibitor [missing]2012-05-10
Discovery and characterization of an inhibitor of glucosylceramide synthase[1]Steven Richards, [2]Christopher J Larson, [3]Elena S Koltun, [4]Art Hanel, [5]Vicky Chan, [6]Jason Nachtigall, [7]Amanda Harrison, [8]Naing Aay, [9]Hongwang Du, [10]Arlyn Arcalas, ... [Full author list]Journal of Medicinal Chemistry [missing]DOI: 10.1021/JM300122U [ORCID]
PubMed: 22497444 [ORCID]
2012-04-19
Discovery of XL413, a potent and selective CDC7 inhibitor[1]Elena S Koltun, [2]Amy Lew Tsuhako, [3]David S Brown, [4]Naing Aay, [5]Arlyn Arcalas, [6]Vicky Chan, [7]Hongwang Du, [8]Stefan Engst, [9]Kim Ferguson, [10]Maurizio Franzini, ... [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2012.04.024 [ORCID]
PubMed: 22560567 [ORCID]
2012-04-16
The design, synthesis, and biological evaluation of PIM kinase inhibitors[1]Amy Lew Tsuhako, [2]David S Brown, [3]Elena S Koltun, [4]Naing Aay, [5]Arlyn Arcalas, [6]Vicky Chan, [7]Hongwang Du, [8]Stefan Engst, [9]Maurizio Franzini, [10]Adam Galan, ... [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2012.04.025 [ORCID]
PubMed: 22542012 [ORCID]
2012-04-11
Discovery of a new class of glucosylceramide synthase inhibitors[1]Elena Koltun, [2]Steven Richards, [3]Vicky Chan, [4]Jason Nachtigall, [5]Hongwang Du, [6]Kevin Noson, [7]Adam Galan, [8]Naing Aay, [9]Art Hanel, [10]Amanda Harrison, ... [Full author list]Bioorganic & Medicinal Chemistry Letters [missing]DOI: 10.1016/J.BMCL.2011.09.037 [ORCID]
PubMed: 21974949 [ORCID]
2011-09-17

Group #2

Matched potential author: Elena S. Koltun - author of 1 items
TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Allosteric inhibition of SHP2 stimulates anti-tumor immunity by transforming the immunosuppressive environment[1]Elsa Quintana, [2]Christopher J Schulze, [3]Darienne R Myers, [4]Tiffany J Choy, [5]Kasia Mordec, [6]David Wildes, [7]Nataliya Tobvis Shifrin, [8]Amira Belwafa, [9]Elena S Koltun, [10]Adrian L Gill, [11]Mallika Singh, [12]Stephen Kelsey, [13]Mark A Goldsmith, [14]Robert Nichols, [15]Jacqueline A M Smith [Full author list]Cancer Research [missing]DOI: 10.1158/0008-5472.CAN-19-3038 [ORCID]
PubMed: 32350067 [ORCID]
2020-04-29Elena S. Koltun (Q125902744; 1 items)
RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers[1]Robert J Nichols, [2]Franziska Haderk, [3]Carlos Stahlhut, [4]Christopher J Schulze, [5]Golzar Hemmati, [6]David Wildes, [7]Christos Tzitzilonis, [8]Kasia Mordec, [9]Abby Marquez, [10]Jason Romero, ..., [16]Zhengping Wang, [17]Gert Kiss, [18]Elena S Koltun, [19]Adrian L Gill, [20]Mallika Singh, ... [Full author list]Nature Cell Biology [missing]DOI: 10.1038/S41556-018-0169-1 [ORCID]
PubMed: 30104724 [ORCID]
2018-08-13Elena S. Koltun (Q125902744; 1 items)

Misc

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Ring scission of diastereomeric 4-butylspiropentylcarbinyl radicals as a chemical model for identifying enzyme-catalyzed FAD adducts resulting from spiropentylacetyl-CoA.[1]Lev Lis, [2]Elena S Koltun, [3]Hung-wen Liu, [4]Steven R Kass [Full author list]Journal of the American Chemical Society [missing]DOI: 10.1021/JA0114862 [ORCID]
PubMed: 11841297 [ORCID]
2002-02-01
Tartaric Acid and Tartrates in the Synthesis of Bioactive Molecules[1]Arun K Ghosh, [2]Elena S Koltun, [3]Geoffrey Bilcer [Full author list]Synthesis [missing]DOI: 10.1055/S-2001-15217 [ORCID]
PubMed: 30393405 [ORCID]
2001-01-01

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NameDescriptionAuthored itemsIdentifiersEmployer(s)
Elena S. Koltun1ORCID: 0009-0005-8720-9097
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