| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication | [1]Renato T Skerlj, [2]Gary J Bridger, [3]Al Kaller, [4]Ernest J McEachern, [5]Jason B Crawford, [6]Yuanxi Zhou, [7]Bem Atsma, [8]Jonathon Langille, [9]Susan Nan, [10]Duane Veale, [11]Trevor Wilson, [12]Curtis Harwig, [13]Sigrid Hatse, [14]Katrien Princen, [15]Erik De Clercq, [16]Dominique Schols [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM100073M [ORCID]
PubMed: 20297846 [ORCID]
| | 2010-04-01 | |
| Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication | [1]Gary J Bridger, [2]Renato T Skerlj, [3]Pedro E Hernandez-Abad, [4]David E Bogucki, [5]Zhongren Wang, [6]Yuanxi Zhou, [7]Susan Nan, [8]Eva M Boehringer, [9]Trevor Wilson, [10]Jason Crawford, [11]Markus Metz, [12]Sigrid Hatse, [13]Katrien Princen, [14]Erik De Clercq, [15]Dominique Schols [Full author list] | Journal of Medicinal Chemistry [missing] | DOI: 10.1021/JM901530B [ORCID]
PubMed: 20043638 [ORCID]
| | 2010-02-01 | |
| The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity | [1]Dana Huskens, [2]Katrien Princen, [3]Michael Schreiber, [4]Dominique Schols [Full author list] | Virology [missing] | DOI: 10.1016/J.VIROL.2007.01.031 [ORCID]
PubMed: 17331556 [ORCID]
| glycosylation [missing]; infectivity [missing] | 2007-02-28 | |
| Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor | [1]Sigrid Hatse, [2]Dana Huskens, [3]Katrien Princen, [4]Kurt Vermeire, [5]Gary J Bridger, [6]Erik De Clercq, [7]Mette M. Rosenkilde, [8]Thue W Schwartz, [9]Dominique Schols [Full author list] | Journal of Virology [missing] | DOI: 10.1128/JVI.01941-06 [ORCID]
PubMed: 17251291 [ORCID]
| ligand binding [missing]; binding pocket [missing] | 2007-01-24 | |
| AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor | [1]Sigrid Hatse, [2]Katrien Princen, [3]Erik De Clercq, [4]Mette M. Rosenkilde, [5]Thue W Schwartz, [6]Pedro E Hernandez-Abad, [7]Renato T Skerlj, [8]Gary J Bridger, [9]Dominique Schols [Full author list] | Biochemical Pharmacology [missing] | DOI: 10.1016/J.BCP.2005.05.035 [ORCID]
PubMed: 16011832 [ORCID]
| | 2005-09-01 | |
| HIV chemokine receptor inhibitors as novel anti-HIV drugs | [1]Katrien Princen, [2]Dominique Schols [Full author list] | Cytokine and Growth Factor Reviews [missing] | DOI: 10.1016/J.CYTOGFR.2005.05.009 [ORCID]
PubMed: 16005254 [ORCID]
| | 2005-07-06 | |
| Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist | [1]Katrien Princen, [2]Sigrid Hatse, [3]Kurt Vermeire, [4]Stefano Aquaro, [5]Erik De Clercq, [6]Lars-Ole Gerlach, [7]Mette M. Rosenkilde, [8]Thue W Schwartz, [9]Renato Skerlj, [10]Gary Bridger, [11]Dominique Schols [Full author list] | Journal of Virology [missing] | DOI: 10.1128/JVI.78.23.12996-13006.2004 [ORCID]
PubMed: 15542651 [ORCID]
| | 2004-12-01 | |
| CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro | [1]Kurt Vermeire, [2]Katrien Princen, [3]Sigrid Hatse, [4]Erik De Clercq, [5]Kaka Dey, [6]Thomas W. Bell, [7]Dominique Schols [Full author list] | AIDS [missing] | DOI: 10.1097/00002030-200411050-00003 [ORCID]
PubMed: 15577644 [ORCID]
| HIV [missing] | 2004-11-01 | |
| Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection | [1]Jan Balzarini, [2]Sigrid Hatse, [3]Kurt Vermeire, [4]Katrien Princen, [5]Stefano Aquaro, [6]Carlo-Federico Perno, [7]Erik De Clercq, [8]Herman Egberink, [9]Guy Vanden Mooter, [10]Willy Peumans, [11]Els Van Damme, [12]Dominique Schols [Full author list] | Antimicrobial Agents and Chemotherapy [missing] | DOI: 10.1128/AAC.48.10.3858-3870.2004 [ORCID]
PubMed: 15388446 [ORCID]
| Amaryllidaceae [missing] | 2004-10-01 | |
| Fluorescent CXCL12AF647 as a novel probe for nonradioactive CXCL12/CXCR4 cellular interaction studies | [1]Sigrid Hatse, [2]Katrien Princen, [3]Sandra Liekens, [4]Kurt Vermeire, [5]Erik De Clercq, [6]Dominique Schols [Full author list] | Cytometry Part A [missing] | DOI: 10.1002/CYTO.A.20070 [ORCID]
PubMed: 15382150 [ORCID]
| | 2004-10-01 | |
| Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists | [1]Katrien Princen, [2]Sigrid Hatse, [3]Kurt Vermeire, [4]Erik De Clercq, [5]Dominique Schols [Full author list] | Retrovirology [missing] | DOI: 10.1186/1742-4690-1-2 [ORCID]
PubMed: 15169555 [ORCID]
| cell line [missing] | 2004-01-01 | |
| The antiviral activity of the CXCR4 antagonist AMD3100 is independent of the cytokine-induced CXCR4/HIV coreceptor expression level | [1]Katrien Princen, [2]Sigrid Hatse, [3]Kurt Vermeire, [4]Gary J Bridger, [5]Renato T Skerlj, [6]Erik De Clercq, [7]Dominique Schols [Full author list] | AIDS Research and Human Retroviruses [missing] | DOI: 10.1089/088922203771881239 [ORCID]
PubMed: 14709250 [ORCID]
| | 2003-12-01 | |
| Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry | [1]Sigrid Hatse, [2]Katrien Princen, [3]Kurt Vermeire, [4]Lars-Ole Gerlach, [5]Mette M. Rosenkilde, [6]Thue W Schwartz, [7]Gary Bridger, [8]Erik De Clercq, [9]Dominique Schols [Full author list] | FEBS Letters [missing] | DOI: 10.1016/S0014-5793(03)00609-4 [ORCID]
PubMed: 12832058 [ORCID]
| antibody [missing] | 2003-07-01 | |
| Evaluation of SDF-1/CXCR4-induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry | [1]Katrien Princen, [2]Sigrid Hatse, [3]Kurt Vermeire, [4]Erik De Clercq, [5]Dominique Schols [Full author list] | Cytometry Part A [missing] | DOI: 10.1002/CYTO.A.10008 [ORCID]
PubMed: 12500303 [ORCID]
| flow cytometry [missing] | 2003-01-01 | |
| CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor | [1]Kurt Vermeire, [2]Ying Zhang, [3]Katrien Princen, [4]Sigrid Hatse, [5]Meinrado F Samala, [6]Kaka Dey, [7]Heung-Jin Choi, [8]Youngmi Ahn, [9]Andrej Sodoma, [10]Robert Snoeck, [11]Graciela Andrei, [12]Erik De Clercq, [13]Thomas W. Bell, [14]Dominique Schols [Full author list] | Virology [missing] | DOI: 10.1006/VIRO.2002.1624 [ORCID]
PubMed: 12441078 [ORCID]
| Human herpesvirus 7 [missing] | 2002-10-01 | |
| Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4. | [1]Sigrid Hatse, [2]Katrien Princen, [3]Gary Bridger, [4]Erik De Clercq, [5]Dominique Schols [Full author list] | FEBS Letters [missing] | DOI: 10.1016/S0014-5793(02)03143-5 [ORCID]
PubMed: 12220670 [ORCID]
| | 2002-09-01 | |