| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy | [1]Talia Caspi, [2]Sam Straw, [3]Chew Cheng, [4]Jack O Garnham, [5]Jason L Scragg, [6]Jessica Smith, [7]Aaron O Koshy, [8]Eylem Levelt, [9]Piruthivi Sukumar, [10]John Gierula, [11]David J Beech, [12]Mark T Kearney, [13]Richard Cubbon, [14]Stephen B Wheatcroft, [15]Klaus K. Witte, [16]Lee D Roberts, [17]T Scott Bowen [Full author list] | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease [missing] | DOI: 10.1161/JAHA.120.017091 [ORCID]
PubMed: 32892688 [ORCID]
| | 2020-09-05 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance related vascular damage | [1]Azhar Maqbool, [2]Nicole Watt, [3]Natalie Haywood, [4]Hema Viswambharan, [5]Anna Skromna, [6]Natallia Makava, [7]Asjad Visnagri, [8]Heba M Shawer, [9]Katherine Bridge, [10]Shovkat K Muminov, [11]Kathryn Griffin, [12]David J Beech, [13]Stephen B Wheatcroft, [14]Karen E Porter, [15]Katie J Simmons, [16]Piruthivi Sukumar, [17]Ajay M Shah, [18]Richard M Cubbon, [19]Mark T Kearney, [20]Nadira Y Yuldasheva [Full author list] | American Journal of Physiology - Cell Physiology [missing] | DOI: 10.1152/AJPCELL.00389.2019 [ORCID]
PubMed: 32401607 [ORCID]
| insulin resistance [missing] | 2020-05-13 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Piezo1 channel agonist mimics high glucose as a stimulator of insulin release | [1]Vijayalakshmi Deivasikamani, [2]Savitha Dhayalan, [3]Romana S Mughal, [4]Asjad Visnagri, [5]Kevin Cuthbertson, [6]Jason L Scragg, [7]Tim S Munsey, [8]Hema Viswambharan, [9]Richard Foster, [10]Asipu Sivaprasadarao, [11]Mark Kearney, [12]David J. Beech, [13]Piruthivi Sukumar [Full author list] | | DOI: 10.1101/455832 [ORCID]
| | 2018-10-29 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice | [1]Anshuman Sengupta, [2]Peysh A Patel, [3]Nadira Yuldasheva, [4]Romana S Mughal, [5]Stacey Galloway, [6]Hema Viswambharan, [7]Andrew M N Walker, [8]Amir Aziz Alkatiri, [9]Jessica Smith, [10]Noman Ali, [11]Ben N Mercer, [12]Helen Imrie, [13]Piruthivi Sukumar, [14]Stephen Wheatcroft, [15]Mark Kearney, [16]Richard Cubbon [Full author list] | Endocrinology [missing] | DOI: 10.1210/EN.2018-00215 [ORCID]
PubMed: 29796592 [ORCID]
| haploinsufficiency [missing]; preproinsulin [missing] | 2018-08-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance | [1]Baptiste Rode, [2]Jian Shi, [3]Naima Endesh, [4]Mark J Drinkhill, [5]Peter J Webster, [6]Sabine J Lotteau, [7]Marc Bailey, [8]Nadira Yuldasheva, [9]Melanie J Ludlow, [10]Richard Cubbon, ..., [18]Paul D Baxter, [18-Q47034621]Paul D. Baxter, [19]Richard Foster, [20]Piruthivi Sukumar, [21]Andrew Weightman, [22]Sarah C Calaghan, ... [Full author list] | Nature Communications [missing] | DOI: 10.1038/S41467-017-00429-3 [ORCID]
PubMed: 28839146 [ORCID]
| | 2017-08-24 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop | [1]Hema Viswambharan, [2]Nadira Yuldasheva, [3]Anshuman Sengupta, [4]Helen Imrie, [5]Matthew C Gage, [6]Natalie North, [7]Andrew M N Walker, [8]Anna Skromna, [9]Natallia Makova, [10]Stacey Galloway, [11]Pooja Shah, [12]Piruthivi Sukumar, [13]Karen E Porter, [14]Peter J Grant, ... [Full author list] | Circulation Research [missing] | DOI: 10.1161/CIRCRESAHA.116.309678 [ORCID]
PubMed: 27920123 [ORCID]
| endothelium [missing]; preproinsulin [missing] | 2016-12-05 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential. | [1]Richard Cubbon, [2]Nadira Yuldasheva, [3]Hema Viswambharan, [4]Ben N Mercer, [5]Vivek Baliga, [6]Sam L Stephen, [7]Jonathan Askham, [8]Piruthivi Sukumar, [9]Anna Skromna, [10]Romana S Mughal, ... [Full author list] | Stem Cells [missing] | DOI: 10.1002/STEM.1766 [ORCID]
PubMed: 24916783 [ORCID]
| | 2014-10-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype. | [1]Nadira Yuldasheva, [2]Sheikh Tawqeer Rashid, [3]Natalie North, [4]Paul Andrew Cordell, [5]Romana S Mughal, [6]Hema Viswambharan, [7]Helen Imrie, [8]Piruthivi Sukumar, [9]Richard Cubbon, [10]Amir Aziz Alkatiri, [11]Matthew Gage, [12]Kamatamu Amanda Mbonye, [13]Jessica Smith, [14]Stacey Galloway, [15]Anna Skromna, [16]D Julian A Scott, [17]Mark Kearney, [18]Stephen Wheatcroft [Full author list] | Arteriosclerosis, Thrombosis, and Vascular Biology [missing] | DOI: 10.1161/ATVBAHA.114.304121 [ORCID]
PubMed: 25012136 [ORCID]
| haploinsufficiency [missing] | 2014-07-10 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Response to Comment on: Sukumar et al. Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes 2013;62:2130-2134. | [1]Piruthivi Sukumar, [2]Mark Kearney [Full author list] | Diabetes [missing] | DOI: 10.2337/DB13-1392 [ORCID]
PubMed: 24264411 [ORCID]
| endothelium [missing]; insulin resistance [missing] | 2013-12-01 | |
| Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: a role for reactive oxygen species | [1]Matthew C Gage, [2]Nadira Yuldasheva, [3]Hema Viswambharan, [4]Piruthivi Sukumar, [5]Richard Cubbon, [6]Stacey Galloway, [7]Helen Imrie, [8]Anna Skromna, [9]Jessica Smith, [10]Christopher L Jackson, [11]Mark Kearney, [12]Stephen Wheatcroft [Full author list] | Atherosclerosis [missing] | DOI: 10.1016/J.ATHEROSCLEROSIS.2013.06.017 [ORCID]
PubMed: 23958265 [ORCID]
| endothelium [missing]; reactive oxygen species [missing]; insulin resistance [missing]; preproinsulin [missing]; atherosclerosis [missing] | 2013-06-29 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction | [1]Piruthivi Sukumar, [2]Hema Viswambharan, [3]Helen Imrie, [4]Richard Cubbon, [5]Nadira Yuldasheva, [6]Matthew Gage, [7]Stacey Galloway, [8]Anna Skromna, [9]Parkavi Kandavelu, [10]Célio Dias Santos Júnior, [11]V Kate Gatenby, [12]Jessica Smith, [13]David J. Beech, [14]Stephen Wheatcroft, [15]Keith Channon, [16]Ajay M. Shah, [17]Mark Kearney [Full author list] | Diabetes [missing] | DOI: 10.2337/DB12-1294 [ORCID]
PubMed: 23349484 [ORCID]
| endothelium [missing]; insulin resistance [missing]; preproinsulin [missing] | 2013-01-24 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice | [1]Helen Imrie, [2]Hema Viswambharan, [3]Piruthivi Sukumar, [4]Afroze Abbas, [5]Richard Cubbon, [6]Nadira Yuldasheva, [7]Matthew Gage, [8]Jessica Smith, [9]Stacey Galloway, [10]Anna Skromna, [11]Sheik Taqweer Rashid, [12]T Simon Futers, [13]Shouhong Xuan, [14]V Kate Gatenby, [15]Peter J Grant, [16]Keith Channon, [17]David J. Beech, [18]Stephen Wheatcroft, [19]Mark Kearney [Full author list] | Diabetes [missing] | DOI: 10.2337/DB11-1494 [ORCID]
PubMed: 22733797 [ORCID]
| endothelium [missing] | 2012-06-25 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin | [1]Piruthivi Sukumar, [2]Alicia Sedo, [3]Jing Li, [4]Lesley A Wilson, [5]David O'Regan, [6]Jonathan D Lippiat, [7]Karen E Porter, [8]Mark Kearney, [9]Justin F X Ainscough, [10]David J. Beech [Full author list] | Circulation Research [missing] | DOI: 10.1161/CIRCRESAHA.112.270751 [ORCID]
PubMed: 22668831 [ORCID]
| fatty acid [missing]; adipocyte [missing] | 2012-06-05 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis | [1]Adil Rajwani, [2]Adil Rajwani, [3]Vivienne A Ezzat, [4]Jessica Smith, [5]Nadira Yuldasheva, [6]Edward R Duncan, [7]Matthew Gage, [8]Richard Cubbon, [9]Matthew Benjamin Kahn, [10]Helen Imrie, ..., [12]Hema Viswambharan, [13]Amir Aziz Alkatiri, [14]Piruthivi Sukumar, [15]Antonio Vidal-Puig, [16]Jaswinder K. Sethi, ... [Full author list] | Diabetes [missing] | DOI: 10.2337/DB11-0963 [ORCID]
PubMed: 22357965 [ORCID]
| atherosclerosis [missing] | 2012-02-22 | Piruthivi Sukumar (Q80439201; 5 items)
|
| The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium | [1]Afroze Abbas, [2]Helen Imrie, [3]Hema Viswambharan, [4]Piruthivi Sukumar, [5]Adil Rajwani, [6]Richard Cubbon, [7]Matthew Gage, [8]Jessica Smith, [9]Stacey Galloway, [10]Nadira Yuldeshava, [11]Matthew Benjamin Kahn, [12]Shouhong Xuan, [13]Peter J. Grant, [14]Keith M. Channon, [15]David J. Beech, [16]Stephen Wheatcroft, [17]Mark Kearney, [18]Keith Channon [Full author list] | Diabetes [missing] | DOI: 10.2337/DB11-0197 [ORCID]
PubMed: 21677284 [ORCID]
| endothelium [missing]; bioavailability [missing]; preproinsulin [missing]; Insulin-like growth factor 1 [missing]; Insulin-like growth factor I receptor [missing] | 2011-08-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels | [1]Yasser Majeed, [2]Yahya M Bahnasi, [3]Victoria A L Seymour, [4]Lesley A Wilson, [5]Carol J Milligan, [6]Anil K Agarwal, [7]Piruthivi Sukumar, [8]Jacqueline Naylor, [9]David J. Beech [Full author list] | Molecular Pharmacology [missing] | DOI: 10.1124/MOL.110.069922 [ORCID]
PubMed: 21406603 [ORCID]
| (RS)-rosiglitazone [missing] | 2011-03-15 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Insulin resistance impairs circulating angiogenic progenitor cell function and delays endothelial regeneration | [1]Matthew Benjamin Kahn, [2]Nadira Yuldasheva, [3]Richard Cubbon, [4]Jessica Smith, [5]Sheikh T Rashid, [6]Hema Viswambharan, [7]Helen Imrie, [8]Afroze Abbas, [9]Adil Rajwani, [10]Amir Aziz Alkatiri, [11]Vivek Baliga, [12]Piruthivi Sukumar, [13]Matthew Gage, [14]Mark Kearney, [15]Stephen Wheatcroft [Full author list] | Diabetes [missing] | DOI: 10.2337/DB10-1080 [ORCID]
PubMed: 21317296 [ORCID]
| endothelium [missing]; insulin resistance [missing]; preproinsulin [missing]; cell function [missing] | 2011-02-11 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers | [1]Alex Cheong, [2]Jing Li, [3]Piruthivi Sukumar, [4]Bhaskar Kumar, [5]Fanning Zeng, [6]Kirsten Riches, [7]Christopher Munsch, [8]Ian C Wood, [9]Karen E Porter, [10]David J. Beech [Full author list] | Cardiovascular Research [missing] | DOI: 10.1093/CVR/CVQ305 [ORCID]
PubMed: 20884640 [ORCID]
| cell migration [missing] | 2011-02-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| TRPM3 channel stimulated by pregnenolone sulphate in synovial fibroblasts and negatively coupled to hyaluronan | [1]Coziana Ciurtin, [2]Yasser Majeed, [3]Jacqueline Naylor, [4]Piruthivi Sukumar, [5]Anne A English, [6]Paul Emery, [7]David J. Beech [Full author list] | BMC Musculoskeletal Disorders [missing] | DOI: 10.1186/1471-2474-11-111 [ORCID]
PubMed: 20525329 [ORCID]
| | 2010-06-04 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells | [1]Ching-On Wong, [2]Piruthivi Sukumar, [3]David J. Beech, [4]Xiaoqiang Yao [Full author list] | Pfluegers Archiv [missing] | DOI: 10.1007/S00424-010-0823-3 [ORCID]
PubMed: 20390293 [ORCID]
| endothelium [missing] | 2010-06-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction | [1]Jacqueline Naylor, [2]Jing Li, [3]Carol J Milligan, [4]Fanning Zeng, [5]Piruthivi Sukumar, [6]Bing Hou, [7]Alicia Sedo, [8]Nadira Yuldasheva, [9]Yasser Majeed, [10]Dhananjay Beri, ... [Full author list] | Circulation Research [missing] | DOI: 10.1161/CIRCRESAHA.110.219329 [ORCID]
PubMed: 20360246 [ORCID]
| | 2010-04-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb2+) | [1]Piruthivi Sukumar, [1-Q80439201]Piruthivi Sukumar, [2]David J. Beech [Full author list] | Biochemical and Biophysical Research Communications [missing] | DOI: 10.1016/J.BBRC.2010.01.074 [ORCID]
PubMed: 20100462 [ORCID]
| lead [missing] | 2010-01-25 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Robotic multiwell planar patch-clamp for native and primary mammalian cells | [1]Carol J Milligan, [2]Jing Li, [3]Piruthivi Sukumar, [4]Yasser Majeed, [5]Mark L. Dallas, [6]Anne English, [7]Paul Emery, [8]Karen E Porter, [9]Andrew M Smith, [10]Ian McFadzean, ... [Full author list] | Nature Protocols [missing] | DOI: 10.1038/NPROT.2008.230 [ORCID]
PubMed: 19197268 [ORCID]
| | 2009-01-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells | [1]Jing Li, [2]Piruthivi Sukumar, [3]Carol J Milligan, [4]Bhaskar Kumar, [5]Zhi-Yong Ma, [6]Christopher M Munsch, [7]Lin-Hua Jiang, [8]Karen E Porter, [9]David J. Beech [Full author list] | Circulation Research [missing] | DOI: 10.1161/CIRCRESAHA.108.182931 [ORCID]
PubMed: 18802022 [ORCID]
| | 2008-09-18 | Piruthivi Sukumar (Q80439201; 5 items)
|
| TRPC channel activation by extracellular thioredoxin | [1]Shang-Zhong Xu, [2]Piruthivi Sukumar, [3]Fanning Zeng, [4]Jing Li, [5]Amit Jairaman, [6]Anne English, [7]Jacqueline Naylor, [8]Coziana Ciurtin, [9]Yasser Majeed, [10]Carol J Milligan, [11]Yahya M Bahnasi, [12]Eman Al-Shawaf, [13]Karen E Porter, [14]Lin-Hua Jiang, [15]Paul Emery, [16]Asipu Sivaprasadarao, [17]David J. Beech [Full author list] | Nature [missing] | DOI: 10.1038/NATURE06414 [ORCID]
PubMed: 18172497 [ORCID]
| | 2008-01-03 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Channel regulation by extracellular redox protein | [1]David J. Beech, [2]Piruthivi Sukumar, [2-Q80439201]Piruthivi Sukumar [Full author list] | Channels [missing] | DOI: 10.4161/CHAN.1.6.5729 [ORCID]
PubMed: 18690048 [ORCID]
| | 2007-11-01 | Piruthivi Sukumar (Q80439201; 5 items)
|
| A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility | [1]Shang-Zhong Xu, [2]Katsuhiko Muraki, [3]Fanning Zeng, [4]Jing Li, [5]Piruthivi Sukumar, [6]Samir Shah, [7]Alexandra M Dedman, [8]Philippa K Flemming, [9]Damian McHugh, [10]Jacqueline Naylor, [11]Alex Cheong, [12]Alan N Bateson, [13]Christopher M Munsch, [14]Karen E Porter, [15]David J. Beech [Full author list] | Circulation Research [missing] | DOI: 10.1161/01.RES.0000225284.36490.A2 [ORCID]
PubMed: 16675717 [ORCID]
| | 2006-05-04 | Piruthivi Sukumar (Q80439201; 5 items)
|
| Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation | [1]Alex Cheong, [2]Andrew J Bingham, [3]Jing Li, [4]Bhaskar Kumar, [5]Piruthivi Sukumar, [6]Christopher Munsch, [7]Noel J Buckley, [8]Craig B Neylon, [9]Karen E Porter, [10]David J. Beech, [11]Ian C Wood [Full author list] | Molecular Cell [missing] | DOI: 10.1016/J.MOLCEL.2005.08.030 [ORCID]
PubMed: 16209944 [ORCID]
| | 2005-10-01 | Piruthivi Sukumar (Q80439201; 5 items)
|