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Lawrence Rosenberg

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Listed Publications

60 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β-cells[1]Jeff Ji, [2]Maria Petropavlovskaia, [3]Armen Khatchadourian, [4]Jason Patapas, [5]Julia Makhlin, [6]Lawrence Rosenberg, [7]Dusica Maysinger [Full author list]Journal of Cellular and Molecular Medicine [curation]DOI: 10.1111/JCMM.14172
PubMed: 30710421
autophagy [curation]; type 2 diabetes [curation]2019-02-01
Erratum. Small Interfering RNA-Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045-3055.[1]Lucy Marzban, [2]Alejandra Tomas, [3]Thomas C Becker, [4]Lawrence Rosenberg, [5]Jose Oberholzer, [6]Paul E Fraser, [7]Philippe A Halban, [8]C Bruce Verchere [Full author list]Diabetes [curation]DOI: 10.2337/DB16-ER03
PubMed: 26908907
2016-03-01
Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development[1]Béatrice Assouline-Thomas, [2]Daniel Ellis, [3]Maria Petropavlovskaia, [4]Julia Makhlin, [5]Jieping Ding, [6]Lawrence Rosenberg [Full author list]Differentiation [curation]DOI: 10.1016/J.DIFF.2015.10.008
PubMed: 26558987
2015-11-11
A Dash of Salt-Inducible Kinase 1 Keeps Insulin Levels in Check.[1]Reid Aikin, [2]Lawrence Rosenberg [Full author list]Diabetes [curation]DOI: 10.2337/DB15-0692
PubMed: 26294426
2015-09-01
Dielectric spectroscopy for non-invasive monitoring of epithelial cell differentiation within three-dimensional scaffolds[1]Jamal Daoud, [2]Koji Asami, [3]Lawrence Rosenberg, [4]Maryam Tabrizian [Full author list]Physics in Medicine and Biology [curation]DOI: 10.1088/0031-9155/57/16/5097
PubMed: 22837013
cell differentiation [curation]2012-08-21
Mechanisms of action of islet neogenesis-associated protein: comparison of the full-length recombinant protein and a bioactive peptide[1]Maria Petropavlovskaia, [2]Jamal Daoud, [3]Jonathan Zhu, [4]Mandana Moosavi, [5]Jieping Ding, [6]Julia Makhlin, [7]Beatrice Assouline-Thomas, [8]Lawrence Rosenberg [Full author list]American Journal of Physiology - Endocrinology and Metabolism [curation]DOI: 10.1152/AJPENDO.00670.2011
PubMed: 22850686
2012-07-31
Epidermal growth factor induces adult human islet cell dedifferentiation.[1]Stephen C Hanley, [2]Béatrice Assouline-Thomas, [3]Julia Makhlin, [4]Lawrence Rosenberg [Full author list]Journal of Endocrinology [curation]DOI: 10.1530/JOE-11-0213
PubMed: 21933872
2011-09-20
Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds[1]Jamal T Daoud, [2]Maria S Petropavlovskaia, [3]Jason M Patapas, [4]Christian E Degrandpré, [5]Robert W Diraddo, [6]Lawrence Rosenberg, [7]Maryam Tabrizian [Full author list]Biomaterials [curation]DOI: 10.1016/J.BIOMATERIALS.2010.10.036
PubMed: 21093908
2010-11-19
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes.[1]Stephen C Hanley, [2]Emily Austin, [3]Béatrice Assouline-Thomas, [4]Jordanna Kapeluto, [5]Jason Blaichman, [6]Mandana Moosavi, [7]Maria Petropavlovskaia, [8]Lawrence Rosenberg [Full author list]Endocrinology [curation]DOI: 10.1210/EN.2009-1277
PubMed: 20176718
type 2 diabetes [curation]2010-02-22
The effect of extracellular matrix components on the preservation of human islet function in vitro[1]Jamal Daoud, [2]Maria Petropavlovskaia, [3]Lawrence Rosenberg, [4]Maryam Tabrizian [Full author list]Biomaterials [curation]DOI: 10.1016/J.BIOMATERIALS.2009.11.057
PubMed: 20015544
extracellular matrix [curation]2009-12-16
Production and characterization of the recombinant Islet Neogenesis Associated Protein (rINGAP).[1]Béatrice Assouline-Thomas, [2]Amélie Pilotte, [3]Maria Petropavlovskaia, [4]Julia Makhlin, [5]Jieping Ding, [6]David McLeod, [7]Stephen Hanley, [8]Bernard Massie, [9]Lawrence Rosenberg [Full author list]Protein Expression and Purification [curation]DOI: 10.1016/J.PEP.2009.07.009
PubMed: 19635567
2009-07-25
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells[1]Lars G Grunnet, [2]Reid Aikin, [3]Morten F Tonnesen, [4]Steven Paraskevas, [5]Lykke Blaabjerg, [6]Joachim Størling, [7]Lawrence Rosenberg, [8]Nils Billestrup, [9]Dusica Maysinger, [10]Thomas Mandrup-Poulsen [Full author list]Diabetes [curation]DOI: 10.2337/DB08-0178
PubMed: 19470609
apoptotic process [curation]2009-05-26
Block-copolymer micelles as carriers of cell signaling modulators for the inhibition of JNK in human islets of Langerhans[1]Radoslav Savić, [2]Tony Azzam, [3]Adi Eisenberg, [4]Hinyu Nedev, [5]Lawrence Rosenberg, [6]Dusica Maysinger [Full author list]Biomaterials [curation]DOI: 10.1016/J.BIOMATERIALS.2009.03.028
PubMed: 19342094
micelles [curation]2009-04-01
Amyloid inhibitors enhance survival of cultured human islets[1]Kathryn J Potter, [2]Louise A Scrocchi, [3]Garth L Warnock, [4]Ziliang Ao, [5]Marika A Younker, [6]Lawrence Rosenberg, [7]Mark Lipsett, [8]C Bruce Verchere, [9]Paul E Fraser [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/J.BBAGEN.2009.02.013
PubMed: 19264107
2009-03-02
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture[1]Lucy Marzban, [2]Alejandra Tomas, [3]Thomas C Becker, [4]Lawrence Rosenberg, [5]Jose Oberholzer, [6]Paul E Fraser, [7]Philippe A Halban, [8]C Bruce Verchere [Full author list]Diabetes [curation]DOI: 10.2337/DB08-0485
PubMed: 18694973
2008-08-11
Cellular origins of adult human islet in vitro dedifferentiation[1]Stephen C Hanley, [2]Amélie Pilotte, [3]Bernard Massie, [4]Lawrence Rosenberg [Full author list]Laboratory Investigation [curation]DOI: 10.1038/LABINVEST.2008.41
PubMed: 18490899
2008-05-19
Donor and isolation variables predicting human islet isolation success[1]Stephen C Hanley, [2]Steven Paraskevas, [3]Lawrence Rosenberg [Full author list]Transplantation [curation]DOI: 10.1097/TP.0B013E3181683DF5
PubMed: 18408573
2008-04-01
Autocrine insulin action activates Akt and increases survival of isolated human islets.[1]R Aikin, [2]S Hanley, [3]Dusica Maysinger, [4]M Lipsett, [5]M Castellarin, [6]S Paraskevas, [7]Lawrence Rosenberg [Full author list]Diabetologia [curation]DOI: 10.1007/S00125-006-0476-0
PubMed: 17053882
2006-10-20
Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.[1]Maria Petropavlovskaia, [2]Julia Makhlin, [3]John Sampalis, [4]Lawrence Rosenberg [Full author list]Journal of Endocrinology [curation]DOI: 10.1677/JOE.1.06800
PubMed: 17065390
2006-10-01
Tumor necrosis factor-alpha production by human islets leads to postisolation cell death.[1]Stephen Hanley, [2]Shuqing Liu, [3]Mark Lipsett, [4]Mauro Castellarin, [5]Lawrence Rosenberg, [6]Jean Tchervenkov, [7]Steven Paraskevas [Full author list]Transplantation [curation]DOI: 10.1097/01.TP.0000234787.05789.23
PubMed: 17006329
cell death [curation]2006-09-01
Neurite outgrowth in dorsal root ganglia induced by islet neogenesis-associated protein peptide involves protein kinase A activation[1]Joseph Tam, [2]Lawrence Rosenberg, [3]Dusica Maysinger [Full author list]NeuroReport [curation]DOI: 10.1097/01.WNR.0000198948.08068.7E
PubMed: 16407769
neurite [curation]2006-02-01
Morphogenetic plasticity of adult human pancreatic islets of Langerhans[1]A-M Jamal, [2]M Lipsett, [3]Robert Sladek, [4]S Laganière, [5]S Hanley, [6]Lawrence Rosenberg [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/SJ.CDD.4401617
PubMed: 15818398
morphogenesis [curation]2005-07-01
INGAP peptide improves nerve function and enhances regeneration in streptozotocin-induced diabetic C57BL/6 mice[1]Joseph Tam, [2]Lawrence Rosenberg, [3]Dusica Maysinger [Full author list]FASEB Journal [curation]DOI: 10.1096/FJ.04-1894FJE
PubMed: 15345684
2004-09-02
40th EASD Annual Meeting of the European Association for the Study of Diabetes[1]M Veitenhansl, ..., [2]K Stegner, [3]F-X Hierl, [4]C Dieterle, [5]H Feldmeier, [6]B Gutt, [7]R Landgraf, [8]A P Garrow, [9]L Vileikyte, [10]A Findlow, ..., [2072]S Hanley, [2073]M Castellarin, [2074]Lawrence Rosenberg, [2075]A Bhushan, [2076]S Georgia, ... [Full author list]Diabetologia [curation]DOI: 10.1007/BF03375463
PubMed: 27770180
diabetes [curation]2004-08-01
Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets[1]Reid Aikin, [2]Dusica Maysinger, [3]Lawrence Rosenberg [Full author list]Endocrinology [curation]DOI: 10.1210/EN.2004-0488
PubMed: 15242986
2004-07-08
Inhibition of caspase-mediated PARP-1 cleavage results in increased necrosis in isolated islets of Langerhans[1]Reid Aikin, [2]Lawrence Rosenberg, [3]Steven Paraskevas, [4]Dusica Maysinger [Full author list]Journal of Molecular Medicine [curation]DOI: 10.1007/S00109-004-0540-5
PubMed: 15105993
2004-04-23
Signals for death and differentiation: a two-step mechanism for in vitro transformation of adult islets of Langerhans to duct epithelial structures[1]Jamal AM, [2]Lipsett M, [3]Hazrati A, [4]Paraskevas S, [5]Agapitos D, [6]Dusica Maysinger, [7]Lawrence Rosenberg [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/SJ.CDD.4401266
PubMed: 12934073
2003-09-01
Islet-neogenesis-associated protein enhances neurite outgrowth from DRG neurons[1]Joseph Tam, [2]Lawrence Rosenberg, [3]Dusica Maysinger [Full author list]Biochemical and Biophysical Research Communications [curation]DOI: 10.1006/BBRC.2002.6497
PubMed: 11855839
neurite [curation]2002-03-01
Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: insulin as an autocrine survival signal[1]S Paraskevas, [2]R Aikin, [3]Dusica Maysinger, [4]J R Lakey, [5]T J Cavanagh, [6]D Agapitos, [7]R Wang, [8]Lawrence Rosenberg [Full author list]Annals of Surgery [curation]DOI: 10.1097/00000658-200101000-00018
PubMed: 11141234
2001-01-01
Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans[1]R Aikin, [2]Lawrence Rosenberg, [3]Dusica Maysinger [Full author list]Biochemical and Biophysical Research Communications [curation]DOI: 10.1006/BBRC.2000.3664
PubMed: 11032744
2000-10-01
Cell loss in isolated human islets occurs by apoptosis[1]S Paraskevas, [2]Dusica Maysinger, [3]R Wang, [4]T P Duguid, [5]Lawrence Rosenberg [Full author list]Pancreas [curation]DOI: 10.1097/00006676-200004000-00008
PubMed: 10766453
apoptotic process [curation]2000-04-01
The structural integrity of the islet in vitro: the effect of incubation temperature[1]A Ilieva, [2]S Yuan, [3]R Wang, [4]W P Duguid, [5]Lawrence Rosenberg [Full author list]Pancreas [curation]DOI: 10.1097/00006676-199910000-00011
PubMed: 10505761
1999-10-01
Structural and functional changes resulting from islet isolation lead to islet cell death.[1]Lawrence Rosenberg, [2]R Wang, [3]S Paraskevas, [4]Dusica Maysinger [Full author list]Surgery [curation]DOI: 10.1016/S0039-6060(99)70183-2
PubMed: 10455912
lead [curation]; cell death [curation]1999-08-01
Activation and expression of ERK, JNK, and p38 MAP-kinases in isolated islets of Langerhans: implications for cultured islet survival[1]S Paraskevas, [2]R Aikin, [3]Dusica Maysinger, [4]J R Lakey, [5]T J Cavanagh, [6]B Hering, [7]R Wang, [8]Lawrence Rosenberg [Full author list]FEBS Letters [curation]DOI: 10.1016/S0014-5793(99)00882-0
PubMed: 10437773
1999-07-01
Early changes of gene expression during cerulein supramaximal stimulation[1]Yuan S, [2]Lawrence Rosenberg, [3]Ilieva A, [4]Agapitos D, [5]Duguid WP [Full author list]Pancreas [curation]DOI: 10.1159/000013424
PubMed: 10416691
1999-07-01
Pancreatic islet cell survival following islet isolation: the role of cellular interactions in the pancreas[1]A Ilieva, [2]S Yuan, [3]R N Wang, [4]D Agapitos, [5]D J Hill, [6]Lawrence Rosenberg [Full author list]Journal of Endocrinology [curation]DOI: 10.1677/JOE.0.1610357
PubMed: 10333538
1999-06-01
Phenotypic modulation of hamster acinar cells by culture in collagen matrix[1]Yuan S, [2]Duguid WP, [3]Agapitos D, [4]Wyllie B, [5]Lawrence Rosenberg [Full author list]Experimental Cell Research [curation]DOI: 10.1006/EXCR.1997.3793
PubMed: 9434620
1997-12-01
Apoptosis occurs in freshly isolated human islets under standard culture conditions[1]S Paraskevas, [2]W P Duguid, [3]Dusica Maysinger, [4]L Feldman, [5]D Agapitos, [6]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]DOI: 10.1016/S0041-1345(96)00452-6
PubMed: 9123509
apoptotic process [curation]1997-02-01
Mechanisms of resistance to injury in pig livers perfused with blood from patients in liver failure[1]A J Tector, [2]N Elias, [3]Lawrence Rosenberg, [4]C Soderland, [5]J Naimi, [6]W P Duguid, [7]J I Tchervenkov [Full author list]Transplantation Proceedings [curation]DOI: 10.1016/S0041-1345(96)00331-4
PubMed: 9123611
liver failure [curation]1997-02-01
Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture.[1]Yuan S, [2]Lawrence Rosenberg, [3]Paraskevas S, [4]Agapitos D, [5]Duguid WP [Full author list]Differentiation [curation]DOI: 10.1046/J.1432-0436.1996.6110067.X
PubMed: 8921586
1996-10-01
Induction of islet cell differentiation and new islet formation in the hamster--further support for a ductular origin[1]Lawrence Rosenberg, [2]R Rafaeloff, [3]D Clas, [4]Y Kakugawa, [5]G Pittenger, [6]A I Vinik, [7]W P Duguid [Full author list]Pancreas [curation]DOI: 10.1097/00006676-199607000-00005
PubMed: 8783332
cell differentiation [curation]1996-07-01
Alterations in pancreatic microcirculation and expression of endothelin-1 in a model of chronic pancreatitis[1]Y Kakugawa, [2]S Paraskevas, [3]P Metrakos, [4]A Giaid, [5]S J Qi, [6]W P Duguid, [7]Lawrence Rosenberg [Full author list]Pancreas [curation]DOI: 10.1097/00006676-199607000-00012
PubMed: 8783339
chronic pancreatitis [curation]1996-07-01
Islet-cell regeneration in the diabetic hamster pancreas with restoration of normoglycaemia can be induced by a local growth factor(s)[1]Lawrence Rosenberg, [2]A I Vinik, [3]G L Pittenger, [4]R Rafaeloff, [5]W P Duguid [Full author list]Diabetologia [curation]DOI: 10.1007/BF00418339
PubMed: 8721769
1996-03-01
Phenotypic transformation of isolated human islets in collagen matrix culture[1]Yuan S, [2]Paraskevas S, [3]Duguid WP, [4]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]PubMed: 85399961995-12-01
Isolation and culture of intralobular ducts from the hamster pancreas[1]S Yuan, [2]P Metrakos, [3]W P Duguid, [4]Lawrence Rosenberg [Full author list]In Vitro Cellular & Developmental Biology - Animal [curation]DOI: 10.1007/BF02633964
PubMed: 7735568
1995-02-01
Cyclosporine A blockade of the induction of ornithine decarboxylase activity as a cause of failure of islet cell proliferation and differentiation[1]Hornby L, [2]Metrakos P, [3]Lawrence Rosenberg [Full author list]Clinical and Investigative Medicine [curation]PubMed: 7895420cyclosporine [curation]1994-12-01
Metabolic evaluation of islets transplanted into the submucosal space[1]Tchervenivanov N, [2]Metrakos P, [3]Yuan S, [4]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]PubMed: 79981441994-12-01
Collagen gel matrix promotes islet cell proliferation[1]Metrakos P, [2]Yuan S, [3]Qi SJ, [4]Duguid WP, [5]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]PubMed: 79981681994-12-01
Paracrine signaling (duct-->islet) in the pancreas and maintenance of islet cell mass--potential implications for islet transplantation[1]Metrakos P, [2]Yuan S, [3]Agapitos D, [4]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]PubMed: 81715881994-04-01
Submucosal transplantation of pancreatic islets[1]Tchervenivanov N, [2]Metrakos P, [3]Kokugawa Y, [4]Lawrence Rosenberg [Full author list]Transplantation Proceedings [curation]PubMed: 81716081994-04-01
Intercellular communication and maintenance of islet cell mass--implications for islet transplantation[1]Metrakos P, [2]Yuan S, [3]Agapitos D, [4]Lawrence Rosenberg [Full author list]Surgery [curation]PubMed: 83421441993-08-01
Cyclosporine and islet mass--implications for islet transplantation[1]Metrakos P, [2]Hornby L, [3]Lawrence Rosenberg [Full author list]Journal of Surgical Research [curation]DOI: 10.1006/JSRE.1993.1060
PubMed: 8331932
cyclosporine [curation]1993-04-01
In vitro stimulation of hamster pancreatic duct growth by an extract derived from the "wrapped" pancreas[1]Lawrence Rosenberg, [2]A I Vinik [Full author list]Pancreas [curation]DOI: 10.1097/00006676-199303000-00018
PubMed: 8460099
1993-03-01
Factors controlling pancreatic islet neogenesis[1]A Vinik, [2]G Pittenger, [3]R Rafaeloff, [4]Lawrence Rosenberg [Full author list]Tumor Biology [curation]PubMed: 82109511993-01-01
Adverse effects of cyclosporine on islet growth and differentiation[1]M A Healey, [2]D Clas, [3]W P Duguid, [4]Lawrence Rosenberg [Full author list]Journal of Surgical Research [curation]DOI: 10.1016/0022-4804(90)90230-Y
PubMed: 2194071
cyclosporine [curation]1990-06-01
Inhibition of pancreatic islet cell differentiation and proliferation by cyclosporine A[1]Healey M, [2]Lawrence Rosenberg, [3]Clas D, [4]Duguid WP [Full author list]Transplantation Proceedings [curation]PubMed: 2183452cell differentiation [curation]; cyclosporine [curation]1990-04-01
The effect of cellophane wrapping of the pancreas in the Syrian golden hamster: autoradiographic observations[1]Lawrence Rosenberg, [2]W P Duguid, [3]A I Vinik [Full author list]Pancreas [curation]DOI: 10.1097/00006676-198902000-00005
PubMed: 2654928
1989-01-01
Preparation of islets of Langerhans from the hamster pancreas[1]Lawrence Rosenberg, [2]R Schwartz, [3]D C Dafoe, [4]S Clarke, [5]J G Turcotte, [6]A I Vinik [Full author list]Journal of Surgical Research [curation]DOI: 10.1016/0022-4804(88)90052-2
PubMed: 2830436
1988-03-01
Induction of nesidioblastosis will reverse diabetes in Syrian golden hamster[1]Lawrence Rosenberg, [2]W P Duguid, [3]R A Brown, [4]A I Vinik [Full author list]Diabetes [curation]DOI: 10.2337/DIAB.37.3.334
PubMed: 2897315
1988-03-01
A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas[1]Lawrence Rosenberg, [2]R A Brown, [3]W P Duguid [Full author list]Journal of Surgical Research [curation]DOI: 10.1016/0022-4804(83)90127-0
PubMed: 6865394
1983-07-01
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