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Karuppiah Muthumani

Wikidata Item | Scholia Profile [curation] | Reasonator | SQID

Listed Publications

47 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses[1]Laura K. Aisenberg, [2]Kimberly E. Rousseau, [3]Katherine Cascino, [4]Guido Massaccesi, [5]William H Aisenberg, [6]Wensheng Luo, [7]Karuppiah Muthumani, [8]David B. Weiner, [9]Stephen S. Whitehead, [10]Michael A. Chattergoon, [11]Anna Durbin, [12]Andrea L Cox [Full author list]JCI insight [curation]DOI: 10.1172/JCI.INSIGHT.151782
2022-06-22
RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance[1]Kumar Sachin Singh, [2]Rishabh Sharma, [3]Poli Adi Narayana Reddy, [4]Prashanthi Vonteddu, [5]Madeline Good, [6]Anjana Sundarrajan, [7]Hyeree Choi, [8]Karuppiah Muthumani, [9]Andrew Kossenkov, [10]Aaron R Goldman, [11]Hsin-Yao Tang, [12]Maxim Totrov, [13]Joel Cassel, [14]Maureen E Murphy, [15]Rajasekharan Somasundaram, [16]Meenhard Herlyn, [17]Joseph M Salvino, [18]Farokh Dotiwala [Full author list]Nature [curation]DOI: 10.1038/S41586-020-03074-X
PubMed: 33361818
2020-12-23
A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus[1]Hyeree Choi, [2]Sagar B Kudchodkar, [3]Michelle Ho, [4]Emma L Reuschel, [5]Erin Reynolds, [6]Ziyang Xu, [7]Devivasha Bordoloi, [8]Kenneth E Ugen, [9]Pablo Tebas, [10]Joseph Kim, [11]Mohamed Abdel-Mohsen, [12]Saravanan Thangamani, [13]David B. Weiner, [14]Karuppiah Muthumani [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0008788
PubMed: 33119599
Powassan virus [curation]2020-10-29
Immunogenicity of a DNA vaccine candidate for COVID-19[1]Trevor R F Smith, [2]Ami Patel, [3]Stephanie J Ramos, [4]Dustin Elwood, [5]Xizhou Zhu, [6]Jian Yan, [7]Ebony N Gary, [8]Susanne N. Walker, [9]Katherine Schultheis, [10]Mansi Purwar, ..., [49]Daniel Wrapp, [50]Jason S. McLellan, [51]Karuppiah Muthumani, [52]Bin Wang, [53]Miles W Carroll, ... [Full author list]Nature Communications [curation]DOI: 10.1038/S41467-020-16505-0
PubMed: 32433465
COVID-19 [curation]; INO-4800 [curation]2020-05-20
Protective immunity by an engineered DNA vaccine for Mayaro virus[1]Hyeree Choi, [2]Sagar B Kudchodkar, [3]Emma L Reuschel, [4]Kanika Asija, [5]Piyush Borole, [6]Michelle Ho, [7]Krzysztof Wojtak, [8]Charles Reed, [9]Stephanie Ramos, [10]Nathen E Bopp, [11]Patricia V Aguilar, [12]Scott C. Weaver, [13]J Joseph Kim, [14]Laurent Humeau, [15]Pablo Tebas, [16]David B. Weiner, [17]Karuppiah Muthumani [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0007042
PubMed: 30730897
Mayaro virus [curation]2019-02-07
Protocols for Developing Novel Chikungunya Virus DNA Vaccines[1]Christopher Chung, [2]Kenneth E Ugen, [3]Niranjan Y Sardesai, [4]David B. Weiner, [5]Karuppiah Muthumani [Full author list]Methods in Molecular Biology [curation]DOI: 10.1007/978-1-4939-3618-2_28
PubMed: 27233283
chikungunya [curation]; Chikungunya virus [curation]2016-01-01
REDD1 Is Essential for Optimal T Cell Proliferation and Survival[1]Emma L Reuschel, [2]JiangFang Wang, [3]Debra K Shivers, [4]Karuppiah Muthumani, [5]David B. Weiner, [6]Zhengyu Ma, [7]Terri H Finkel [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0136323
PubMed: 26301899
2015-08-24
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates[1]Karuppiah Muthumani, [2]Darryl Falzarano, [3]Emma L Reuschel, [4]Colleen Tingey, [5]Seleeke Flingai, [6]Daniel O Villarreal, [7]Megan Wise, [8]Ami Patel, [9]Abdullah Izmirly, [10]Abdulelah Aljuaid, ... [Full author list]Science Translational Medicine [curation]DOI: 10.1126/SCITRANSLMED.AAC7462
PubMed: 26290414
Middle East [curation]; Coronaviridae [curation]; Middle East respiratory syndrome coronavirus [curation]; Middle East respiratory syndrome [curation]2015-08-01
Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy[1]Seleeke Flingai, [2]Emily Plummer, [3]Ami Patel, [4]Sujan Shresta, [5]Janess M Mendoza, [6]Kate E. Broderick, [7]Niranjan Y Sardesai, [8]Karuppiah Muthumani, [9]David B. Weiner [Full author list]Scientific Reports [curation]DOI: 10.1038/SREP12616
PubMed: 26220099
Dengue virus [curation]; immunotherapy [curation]2015-07-29
Safety, bioavailability, and pharmacokinetics of VGX-1027-A novel oral anti-inflammatory drug in healthy human subjects[1]Jessica C Lee, [2]Stanley Menacherry, [3]Malissa C Diehl, [4]Mary D Giffear, [5]C Jo White, [6]Rob Juba, [7]Mark L Bagarazzi, [8]Karuppiah Muthumani, [9]Jean Boyer, [10]Vipin Agarwal, [11]Ferdinando Nicoletti, [12]Stephen Bart, [13]J Joseph Kim, [14]David B. Weiner, [15]Niranjan Y Sardesai [Full author list]Clinical pharmacology in drug development [curation]DOI: 10.1002/CPDD.193
PubMed: 27138022
inflammation [curation]; pharmacokinetics [curation]; bioavailability [curation]; human subject research project [curation]2015-06-08
Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45[1]P Vijayachari, [2]K Vedhagiri, [3]K Mallilankaraman, [4]Premendu Prakash Mathur, [5]Niranjan Y Sardesai, [6]D B Weiner, [7]K E Ugen, [8]Karuppiah Muthumani [Full author list]Human Vaccines & Immunotherapeutics [curation]DOI: 10.1080/21645515.2015.1047117
PubMed: 26020621
2015-05-28
VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus[1]Paolo Fagone, [2]Karuppiah Muthumani, [3]Katia Mangano, [4]Gaetano Magro, [5]Pier Luigi Meroni, [6]Joseph J Kim, [7]Niranjan Y Sardesai, [8]David B. Weiner, [9]Ferdinando Nicoletti [Full author list]Immunology [curation]DOI: 10.1111/IMM.12267
PubMed: 24527796
systemic lupus erythematosus [curation]; toll-like receptor [curation]; lipopolysaccharide [curation]; murine model [curation]2014-08-01
Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity[1]Devon J Shedlock, [2]Colleen Tingey, [3]Lavanya Mahadevan, [4]Natalie Hutnick, [5]Emma L Reuschel, [6]Sagar Kudchodkar, [7]Seleeke Flingai, [8]Jenny Yan, [9]Joseph J Kim, [10]Kenneth E Ugen, [11]David B. Weiner, [12]Karuppiah Muthumani [Full author list]Vaccines [curation]DOI: 10.3390/VACCINES2020196
PubMed: 26344618
NF-κB [curation]2014-03-25
HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo[1]Karuppiah Muthumani, [2]Megan C Wise, [3]Kate E. Broderick, [4]Natalie Hutnick, [5]Jonathan Goodman, [6]Seleeke Flingai, [7]Jian Yan, [8]Chaoran B Bian, [9]Janess Mendoza, [10]Colleen Tingey, [11]Christine Wilson, [12]Krzysztof Wojtak, [13]Niranjan Y Sardesai, [14]David B. Weiner [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0084234
PubMed: 24391921
2013-12-31
Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants[1]Seleeke Flingai, [2]Matias Czerwonko, [3]Jonathan Goodman, [4]Sagar B Kudchodkar, [5]Karuppiah Muthumani, [6]David B. Weiner [Full author list]Frontiers in Immunology [curation]DOI: 10.3389/FIMMU.2013.00354
PubMed: 24204366
vaccine [curation]; electroporation [curation]2013-11-04
Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab.[1]Karuppiah Muthumani, [2]Seleeke Flingai, [3]Megan Wise, [4]Colleen Tingey, [5]Kenneth E Ugen, [6]David B. Weiner [Full author list]Human Vaccines & Immunotherapeutics [curation]DOI: 10.4161/HV.26498
PubMed: 24045230
HIV [curation]2013-09-17
In vivo electroporation of constitutively expressed HIF-1α plasmid DNA improves neovascularization in a mouse model of limb ischemia[1]Geoffrey O Ouma, [2]Eduardo Rodriguez, [3]Karuppiah Muthumani, [4]David B. Weiner, [5]Robert L Wilensky, [6]Emile R Mohler [Full author list]Journal of Vascular Surgery [curation]DOI: 10.1016/J.JVS.2013.04.043
PubMed: 23850058
electroporation [curation]; neovascularization [curation]2013-07-11
Breast cancer drugs dampen vascular functions by interfering with nitric oxide signaling in endothelium[1]Palanivel Gajalakshmi, [2]Mani Krishna Priya, [3]Thangaraj Pradeep, [4]Jyotirmaya Behera, [5]Karuppiah Muthumani, [6]Srinivasan Madhuwanti, [7]Uttara Saran, [8]Suvro Chatterjee [Full author list]Toxicology and Applied Pharmacology [curation]DOI: 10.1016/J.TAAP.2013.03.011
PubMed: 23531514
endothelium [curation]2013-03-24
Nonstructural protein 2 (nsP2) of Chikungunya virus (CHIKV) enhances protective immunity mediated by a CHIKV envelope protein expressing DNA Vaccine[1]Huihui Bao, [2]Aarti A Ramanathan, [3]Omkar Kawalakar, [4]Senthil G Sundaram, [5]Colleen Tingey, [6]Charoran B Bian, [7]Nagarajan Muruganandam, [8]Paluru Vijayachari, [9]Niranjan Y Sardesai, [10]David B. Weiner, [11]Kenneth E Ugen, [12]Karuppiah Muthumani [Full author list]Viral Immunology [curation]DOI: 10.1089/VIM.2012.0061
PubMed: 23409931
chikungunya [curation]; Chikungunya virus [curation]2013-02-01
Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice[1]Devon J Shedlock, [2]Kendra T Talbott, [3]Stephan J Wu, [4]Christine M Wilson, [5]Karuppiah Muthumani, [6]Jean D Boyer, [7]Niranjan Y Sardesai, [8]Sita Awasthi, [9]David B. Weiner [Full author list]Human Vaccines & Immunotherapeutics [curation]DOI: 10.4161/HV.22447
PubMed: 23151448
Cytomegalovirus [curation]2012-11-01
HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells[1]Karuppiah Muthumani, [2]Devon J Shedlock, [3]Daniel K Choo, [4]Paolo Fagone, [5]Omkar U Kawalekar, [6]Jonathan Goodman, [7]Chaoran B Bian, [8]Aarti A Ramanathan, [9]Parikh Atman, [10]Pablo Tebas, [11]Michael A Chattergoon, [12]Andrew Y Choo, [13]David B. Weiner [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1100594
PubMed: 21856939
2011-08-19
Role of proinflammatory cytokines and chemokines in chronic arthropathy in CHIKV infection[1]Itta Krishna Chaaitanya, [2]Nagarajan Muruganandam, [3]Senthil G Sundaram, [4]Omkar Kawalekar, [5]Attayur P Sugunan, [6]Sathya P Manimunda, [7]Sruti R Ghosal, [8]Karuppiah Muthumani, [9]Paluru Vijayachari [Full author list]Viral Immunology [curation]DOI: 10.1089/VIM.2010.0123
PubMed: 21830898
Chikungunya virus [curation]2011-08-01
Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination[1]Paolo Fagone, [2]D J Shedlock, [3]H Bao, [4]O U Kawalekar, [5]J Yan, [6]D Gupta, [7]M P Morrow, [8]A Patel, [9]G P Kobinger, [10]Karuppiah Muthumani, [11]D B Weiner [Full author list]Gene Therapy [curation]DOI: 10.1038/GT.2011.59
PubMed: 21544096
2011-05-05
A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge[1]Devon J Shedlock, [2]Kendra T Talbott, [3]Christina Cress, [4]Bernadette Ferraro, [5]Steven Tuyishme, [6]Karthik Mallilankaraman, [7]Neil J Cisper, [8]Matthew P Morrow, [9]Stephan J Wu, [10]Omkar U Kawalekar, [11]Amir S Khan, [12]Niranjan Y Sardesai, [13]Karuppiah Muthumani, [14]Hao Shen, [15]David B. Weiner [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2010.12.064
PubMed: 21238574
lymphocyte [curation]; lymphocytic choriomeningitis [curation]2011-01-14
A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates[1]Karthik Mallilankaraman, [2]Devon J Shedlock, [3]Huihui Bao, [4]Omkar U Kawalekar, [5]Paolo Fagone, [6]Aarthi A Ramanathan, [7]Bernadette Ferraro, [8]Jennifer Stabenow, [9]Paluru Vijayachari, [10]Senthil G Sundaram, [11]Nagarajan Muruganandam, [12]Gopalsamy Sarangan, [13]Padma Srikanth, [14]Amir S Khan, [15]Mark G. Lewis, [16]J Joseph Kim, [17]Niranjan Y Sardesai, [18]Karuppiah Muthumani, [19]David B. Weiner [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0000928
PubMed: 21264351
antibody [curation]; vaccine [curation]; chikungunya [curation]; Chikungunya virus [curation]2011-01-11
Molecular characterization of Chikungunya virus during an outbreak in South India[1]P Srikanth, [2]G Sarangan, [3]K Mallilankaraman, [4]S A Nayar, [5]R Barani, [6]T Mattew, [7]G F Selvaraj, [8]K A Sheriff, [9]G Palani, [10]Karuppiah Muthumani [Full author list]Indian Journal of Medical Microbiology [curation]DOI: 10.4103/0255-0857.71812
PubMed: 20966558
chikungunya [curation]; Chikungunya virus [curation]2010-10-01
DNA vaccines for targeting bacterial infections[1]Mariana Ingolotti, [2]Omkar Kawalekar, [3]Devon J Shedlock, [4]Karuppiah Muthumani, [5]David B. Weiner [Full author list]Expert Review of Vaccines [curation]DOI: 10.1586/ERV.10.57
PubMed: 20624048
2010-07-01
Chikungunya: a potentially emerging epidemic?[1]Michelle M Thiboutot, [2]Senthil Kannan, [3]Omkar U Kawalekar, [4]Devon J Shedlock, [5]Amir S Khan, [6]Gopalsamy Sarangan, [7]Padma Srikanth, [8]David B. Weiner, [9]Karuppiah Muthumani [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0000623
PubMed: 20436958
epidemic [curation]; chikungunya [curation]; emerging communicable disease [curation]; alphavirus infections [curation]; Chikungunya virus [curation]2010-04-27
Anti-cancer activity of the HIV accessory molecule viral protein R (Vpr): Delivery as a DNA expression plasmid or biologically active peptides[1]Karuppiah Muthumani, [2]Vance M Lambert, [3]Omkar Kawalekar, [4]Richard Heller, [5]J Joseph Kim, [6]David B. Weiner, [7]Kenneth E Ugen [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2009.10.060
PubMed: 20188256
2010-02-01
Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo[1]M A Kutzler, [2]K A Kraynyak, [3]S J Nagle, [4]R M Parkinson, [5]D Zharikova, [6]M Chattergoon, [7]H Maguire, [8]Karuppiah Muthumani, [9]K Ugen, [10]D B Weiner [Full author list]Gene Therapy [curation]DOI: 10.1038/GT.2009.112
PubMed: 19847203
2009-10-22
Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus[1]Karuppiah Muthumani, [2]Katthikbabu M Lankaraman, [3]Dominick J Laddy, [4]Senthil G Sundaram, [5]Christopher W Chung, [6]Eric Sako, [7]Ling Wu, [8]Amir Khan, [9]Niranjan Y Sardesai, [10]Joseph J Kim, [11]Paluru Vijayachari, [12]David B. Weiner [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2008.03.060
PubMed: 18471943
chikungunya [curation]; Chikungunya virus [curation]2008-09-19
Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism[1]Karuppiah Muthumani, [2]Andrew Y Choo, [3]Devon J Shedlock, [4]Dominick J Laddy, [5]Senthil G Sundaram, [6]Lauren Hirao, [7]Ling Wu, [8]Khanh P Thieu, [9]Christopher W Chung, [10]Karthikbabu M Lankaraman, [11]Pablo Tebas, [12]Guido Silvestri, [13]David B. Weiner [Full author list]Journal of Virology [curation]DOI: 10.1128/JVI.00485-08
PubMed: 18799583
2008-09-17
HIV-1 viral genes and mitochondrial apoptosis[1]Devon J Shedlock, [2]Daniel Hwang, [3]Andy Y Choo, [4]Christopher W Chung, [5]Karuppiah Muthumani, [6]David B. Weiner [Full author list]Apoptosis [curation]DOI: 10.1007/S10495-008-0239-0
PubMed: 18622704
HIV [curation]; mitochondrion [curation]; apoptotic process [curation]2008-07-12
The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest[1]Jiangfang Wang, [2]Jason M Shackelford, [3]Nithianandan Selliah, [4]Debra K Shivers, [5]Eduardo O'Neill, [6]J Victor Garcia, [7]Karuppiah Muthumani, [8]David B. Weiner, [9]Xiao-Fang Yu, [10]Dana Gabuzda, [11]Terri H Finkel [Full author list]DNA and Cell Biology [curation]DOI: 10.1089/DNA.2007.0707
PubMed: 18462066
2008-05-01
DR5 activation of caspase-8 induces DC maturation and immune enhancement in vivo[1]Michael A Chattergoon, [2]Karuppiah Muthumani, [3]Yutaka Tamura, [4]Mathura Ramanathan, [5]Jason P Shames, [6]Vera Saulino, [7]Tara M Robinson, [8]Luis J Montaner, [9]David B. Weiner [Full author list]Molecular Therapy [curation]DOI: 10.1038/SJ.MT.6300373
PubMed: 18087262
2007-12-18
Complete Regression of Established Subcutaneous B16 Murine Melanoma Tumors after Delivery of an HIV-1 Vpr-Expressing Plasmid by in Vivo Electroporation[1]Andrea N. McCray, [2]Kenneth E. Ugen, [3]Karuppiah Muthumani, [4]J.J. Kim, [5]David B. Weiner, [6]Richard Heller [Full author list]Molecular Therapy [curation]DOI: 10.1016/J.YMTHE.2006.06.010
PubMed: 16950655
electroporation [curation]2006-11-01
The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1[1]Karuppiah Muthumani, [2]Andrew Y Choo, [3]Wei-Xing Zong, [4]Muniswamy Madesh, [5]Daniel S Hwang, [6]Arumugam Premkumar, [7]Khanh P Thieu, [8]Joann Emmanuel, [9]Sanjeev Kumar, [10]Craig B. Thompson, [11]David B. Weiner [Full author list]Nature Cell Biology [curation]DOI: 10.1038/NCB1352
PubMed: 16429131
cell biology [curation]; glucocorticoid [curation]2006-01-22
SIV DNA vaccine co-administered with IL-12 expression plasmid enhances CD8 SIV cellular immune responses in cynomolgus macaques[1]Jean D Boyer, [2]Tara M Robinson, [3]Michele A Kutzler, [4]R Parkinson, [5]Sandra A Calarota, [6]Maninder K Sidhu, [7]Karuppiah Muthumani, [8]Mark Lewis, [9]George Pavlakis, [10]Barbara Felber, [11]David B. Weiner [Full author list]Journal of Medical Primatology [curation]DOI: 10.1111/J.1600-0684.2005.00124.X
PubMed: 16128921
vaccine [curation]2005-10-01
HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation[1]Karuppiah Muthumani, [2]Andrew Y Choo, [3]Daniel S Hwang, [4]Arumugam Premkumar, [5]Nathanael S Dayes, [6]Crafford Harris, [7]Douglas R. Green, [8]Scott A Wadsworth, [9]John J Siekierka, [10]David B. Weiner [Full author list]Blood [curation]DOI: 10.1182/BLOOD-2005-03-0932
PubMed: 15928037
cell biology [curation]2005-09-15
Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism[1]Karuppiah Muthumani, [2]Choo AY, [3]Premkumar A, [4]Hwang DS, [5]Thieu KP, [6]Desai BM, [7]Weiner DB [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/SJ.CDD.4401583
PubMed: 15832179
cell death [curation]2005-08-01
HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo[1]Karuppiah Muthumani, [2]Andrew Y Choo, [3]Daniel S Hwang, [4]Nathanael S Dayes, [5]Michael Chattergoon, [6]Shanmugam Mayilvahanan, [7]Khanh P Thieu, [8]Peter T Buckley, [9]Joann Emmanuel, [10]Arumugam Premkumar, [11]David B. Weiner [Full author list]Molecular Therapy [curation]DOI: 10.1016/J.YMTHE.2005.05.009
PubMed: 16006193
superantigen [curation]2005-07-11
HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro[1]Karuppiah Muthumani, [2]Daniel S Hwang, [3]Andrew Y Choo, [4]Shanmugam Mayilvahanan, [5]Nathanael S Dayes, [6]Khanh P Thieu, [7]David B. Weiner [Full author list]International Immunology [curation]DOI: 10.1093/INTIMM/DXH190
PubMed: 15611322
macrophage [curation]; dendritic cell [curation]2004-12-20
HIV-1 Vpr and anti-inflammatory activity[1]Karuppiah Muthumani, [2]Brijal M Desai, [3]Daniel S Hwang, [4]Andrew Y Choo, [5]Dominick J Laddy, [6]Khanh P Thieu, [7]Rushil G Rao, [8]David B. Weiner [Full author list]DNA and Cell Biology [curation]DOI: 10.1089/104454904773819824
PubMed: 15142381
inflammation [curation]2004-04-01
Mechanism of HIV-1 viral protein R-induced apoptosis[1]Karuppiah Muthumani, [2]Andrew Y. Choo, [3]Daniel S. Hwang, [4]Michael A. Chattergoon, [5]Nathanael N. Dayes, [6]Donghui Zhang, [7]Mark D. Lee, [8]Umaheswar Duvvuri, [9]David B. Weiner [Full author list]Biochemical and Biophysical Research Communications [curation]DOI: 10.1016/S0006-291X(03)00631-4
PubMed: 12729593
biochemistry [curation]; biophysics [curation]; cell biology [curation]; apoptotic process [curation]2003-05-09
Induction of inflammation by West Nile virus capsid through the caspase-9 apoptotic pathway[1]Joo-Sung Yang, [2]Mathura P Ramanathan, [3]Karuppiah Muthumani, [4]Andrew Y Choo, [5]Sung-Ha Jin, [6]Qian-Chun Yu, [7]Daniel S Hwang, [8]Daniel K Choo, [9]Mark D Lee, [10]Kesen Dang, [11]Waixing Tang, [12]J Joseph Kim, [13]David B. Weiner [Full author list]Emerging Infectious Diseases [curation]DOI: 10.3201/EID0812.020224
PubMed: 12498651
inflammation [curation]; West Nile virus [curation]; apoptotic process [curation]2002-12-01
HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells[1]Karuppiah Muthumani, [2]Daniel S Hwang, [3]Brijal M Desai, [4]Donghui Zhang, [5]Nathanael Dayes, [6]Douglas R. Green, [7]David B. Weiner [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M205313200
PubMed: 12095993
apoptotic process [curation]2002-10-04
The HIV-1 accessory gene vpr can inhibit antigen-specific immune function[1]Karuppiah Muthumani, [2]Daniel S Hwang, [3]Nathaniel S Dayes, [4]J Joseph Kim, [5]David B. Weiner [Full author list]DNA and Cell Biology [curation]DOI: 10.1089/104454902760330237
PubMed: 12396612
cell biology [curation]; molecular biology [curation]; immune function [curation]2002-09-01
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