| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protocol | [1]David A Singleton, [2]Ana Ibarz-Pavon, [3]Todd D Swarthout, [4]Farouck Bonomali, [5]Jennifer Cornick, [6]Akuzike Kalizang’oma, [7]Noah Ntiza, [8]Comfort Brown, [9]Raphael Chipatala, [10]Wongani Nyangulu, [11]James Chirombo, [12]Gift Kawalazira, [13]Henry Chibowa, [14]Charles Mwansambo, [15]Kenneth Mphatso Maleta, [16]Neil French, [17]Robert Heyderman [Full author list] | BMJ Open [curation] | DOI: 10.1136/BMJOPEN-2022-069560
| | 2023-05-01 |
| Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study | [1]Christine Kelly, [2]Rijan Gurung, [3]Raphael Kamng'ona, [4]Irene Sheha, [5]Mishek Chammudzi, [6]Kondwani C Jambo, [7]Jane Mallewa, [8]Alicja Rapala, [9]Robert Heyderman, [10]Patrick Mallon, [11]Henry Mwandumba, [12]Saye Khoo, [13]Nigel Klein [Full author list] | Wellcome Open Research [curation] | DOI: 10.12688/WELLCOMEOPENRES.17044.2
| | 2022-10-17 |
| Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi | [1]Deus Thindwa, [2]Kondwani C Jambo, [3]John Ojal, [4]Peter MacPherson, [5]Mphatso Dennis Phiri, [6]Amy Pinsent, [7]McEwen Khundi, [8]Lingstone Chiume, [9]Katherine E. Gallagher, [10]Robert Heyderman, [11]Elizabeth L. Corbett, [12]Neil French, [13]Stefan Flasche [Full author list] | Epidemics: the journal of infectious disease dynamics [curation] | DOI: 10.1016/J.EPIDEM.2022.100590
| | 2022-09-01 |
| Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi | [1]Deus Thindwa, [2]Thandie S. Mwalukomo, [3]Jacquline Msefula, [4]Kondwani C Jambo, [5]Comfort Brown, [6]Arox Kamng’ona, [7]Charles Mwansambo, [8]John Ojal, [9]Stefan Flasche, [10]Neil French, [11]Robert Heyderman, [12]Todd D. Swarthout [Full author list] | AIDS [curation] | DOI: 10.1097/QAD.0000000000003365
| | 2022-08-19 |
| The histone demethylase KDM6B fine-tunes the host response to Streptococcus pneumoniae | [1]Michael G Connor, [2]Tiphaine M N Camarasa, [3]Emma Patey, [4]Orhan Rasid, [5]Laura Barrio, [6]Caroline M Weight, [7]Daniel P Miller, [8]Robert Heyderman, [9]Richard Lamont, [10]Jost Enninga, [11]Mélanie A. Hamon [Full author list] | Nature Microbiology [curation] | DOI: 10.1038/S41564-020-00805-8
PubMed: 33349663 | Streptococcus pneumoniae [curation] | 2020-12-21 |
| Preclinical Development of Virulence Attenuated Streptococcus pneumoniae Strains Able to Enhance Protective Immunity Against Pneumococcal Infection | [1]Elisa Ramos-Sevillano, [2]Giuseppe Ercoli, [3]Philip L. Felgner, [4]Rafael Ramiro de Assis, [5]Rie Nakajima, [6]David Goldblatt, [7]Robert Heyderman, [8]Stephen B Gordon, [9]Daniela M Ferreira, [10]Jeremy S Brown, [10-Q90929671]Jeremy Brown [Full author list] | American Journal of Respiratory and Critical Care Medicine [curation] | DOI: 10.1164/RCCM.202011-4161LE
PubMed: 33332997 | Streptococcus pneumoniae [curation]; pneumococcal infection [curation] | 2020-12-17 |
| Influenza-like illness is associated with high pneumococcal carriage density in Malawian children | [1]Tinashe K Nyazika, [2]Alice Law, [3]Todd D Swarthout, [4]Lusako Sibale, [5]Danielle Ter Braake, [6]Neil French, [7]Robert Heyderman, [8]Dean Everett, [9]Aras Kadioglu, [10]Kondwani C Jambo, [11]Daniel R Neill [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2020.06.079
PubMed: 32711042 | | 2020-07-22 |
| The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fever Studies: A Review of Methodological Similarities and Differences | [1]Megan E Carey, [2]William R MacWright, [3]Justin Im, [4]James E Meiring, [5]Malick M Gibani, [6]Se Eun Park, [7]Ashley Longley, [8]Hyon Jin Jeon, [9]Caitlin Hemlock, [10]Alexander T Yu, ..., [25]Kashmira Date, [26]Firdausi Qadri, [27]Robert Heyderman, [28]Samir K Saha, [29]Buddha Basnyat, ... [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIAA367
PubMed: 32725221 | typhoid fever [curation] | 2020-07-01 |
| Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia | [1]Deus Thindwa, [2]Yama G Farooq, [3]Mila Shakya, [4]Nirod Saha, [5]Susan Tonks, [6]Yaw Anokwa, [7]Melita A. Gordon, [8]Carl Hartung, [9]James E Meiring, [10]Andrew Pollard, [11]Robert Heyderman, [12]Strategic Typhoid alliance across Africa and Asia consortium [Full author list] | Wellcome Open Research [curation] | DOI: 10.12688/WELLCOMEOPENRES.15811.1
PubMed: 32934993 | contact tracing [curation] | 2020-04-09 |
| Inflammatory Phenotypes Predict Changes in Arterial Stiffness following ART Initiation | [1]Christine Kelly, [2]Willard Tinago, [3]Dagmar Alber, [4]Patricia Hunter, [5]Natasha Luckhurst, [6]Jake Connolly, [7]Francesca Arrigoni, [8]Alejandro Garcia Abner, [9]Ralph Kamngona, [10]Irene Sheha, [11]Mishek Chammudzi, [12]Kondwani C Jambo, [13]Jane Mallewa, [14]Alicja Rapala, [15]Robert Heyderman, [16]Patrick W G Mallon, [17]Henry Mwandumba, [18]Ann Sarah Walker, [19]Nigel Klein, [20]Saye Khoo [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIAA186
PubMed: 32103268 | | 2020-02-27 |
| Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review | [1]Newton L Kalata, [2]Tinashe K Nyazika, [3]Todd D Swarthout, [4]Dean Everett, [5]Neil French, [6]Robert Heyderman, [7]Siamon Gordon, [8]Kondwani C Jambo [Full author list] | BMJ Open [curation] | DOI: 10.1136/BMJOPEN-2019-030981
PubMed: 31727654 | pneumococcal pneumonia [curation] | 2019-11-13 |
| Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study | [1]Ingrid Peterson, [2]Ntobeko Ntsui, [3]Kondwani C Jambo, [4]Christine Kelly, [5]Jacqueline Huwa, [6]Louise Afran, [7]Joseph Kamtchum Tatuene, [8]Sarah Pett, [9]Marc Henrion, [10]Joep Van Oosterhout, [11]Robert Heyderman, [12]Henry Mwandumba, [13]Laura A Benjamin, [14]Investigators of the RHICCA study [Full author list] | BMJ Open [curation] | DOI: 10.1136/BMJOPEN-2018-025576
PubMed: 31515413 | | 2019-09-12 |
| Community-acquired acute bacterial meningitis in adults: a clinical update | [1]Jayne Ellis, [2]Akish Luintel, [3]Arjun Chandna, [4]Robert Heyderman [Full author list] | British Medical Bulletin [curation] | DOI: 10.1093/BMB/LDZ023
PubMed: 31556944 | meningitis [curation]; bacterial meningitis [curation] | 2019-09-01 |
| Early T Cell Differentiation with Well-Maintained Function across the Adult Life Course in Sub-Saharan Africa | [1]David J C Miles, [2]Florence Shumba, [3]Annette Pachnio, [4]Jusnara Begum, [5]Elizabeth L Corbett, [6]Robert Heyderman, [7]Paul Moss [Full author list] | Journal of Immunology [curation] | DOI: 10.4049/JIMMUNOL.1800866
PubMed: 31358657 | Sub-Saharan Africa [curation]; cell differentiation [curation] | 2019-07-29 |
| Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface | [1]Caroline M Weight, [2]Cristina Venturini, [3]Sherin Pojar, [4]Simon P Jochems, [5]Jesús Reiné, [6]Elissavet Nikolaou, [7]Carla Solórzano, [8]Mahdad Noursadeghi, [9]Jeremy Brown, [10]Daniela M Ferreira, [11]Robert Heyderman [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-019-11005-2
PubMed: 31311921 | Streptococcus pneumoniae [curation] | 2019-07-16 |
| Emerging resistance to empiric antimicrobial regimens for pediatric bloodstream infections in Malawi (1998-2017) | [1]Pui-Ying Iroh Tam, [2]Patrick Musicha, [3]Kondwani Kawaza, [4]Jen Cornick, [5]Brigitte Denis, [6]Bridget Freyne, [7]Dean Everett, [8]Queen Dube, [9]Neil French, [10]Nicholas A Feasey, [11]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIY834
PubMed: 30277505 | Malawi [curation]; antimicrobial resistance [curation] | 2019-06-01 |
| Aetiology and Risk Factors for Mortality in an Adult Community-Acquired Pneumonia Cohort in Malawi | [1]Stephen J Aston, [1-Q57417081]Stephen Aston, [2]Antonia Ho, [3]Hannah Jary, [4]Jacqueline Huwa, [5]Tamara Mitchell, [6]Sarah Ibitoye, [7]Simon Greenwood, [8]Elizabeth Joekes, [9]Arthur Daire, [10]Jane Mallewa, [11]Dean Everett, [12]Mulinda Nyirenda, [13]Brian Faragher, [14]Henry Mwandumba, [15]Robert Heyderman, [16]Stephen B Gordon [Full author list] | American Journal of Respiratory and Critical Care Medicine [curation] | DOI: 10.1164/RCCM.201807-1333OC
PubMed: 30625278 | Malawi [curation] | 2019-01-09 |
| HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy | [1]Christine Kelly, [2]Henry Mwandumba, [3]Robert Heyderman, [4]Kondwani C Jambo, [5]Raphael Kamng'ona, [6]Mishek Chammudzi, [7]Irene Sheha, [8]Ingrid Peterson, [9]Alicja Rapala, [10]Jane Mallewa, [11]Ann Sarah Walker, [12]Nigel Klein, [13]Saye Khoo [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIZ015
PubMed: 30629187 | infectious disease [curation]; T cell exhaustion [curation] | 2019-01-09 |
| Cerebrospinal fluid transcriptional analyses reveals upregulation of IL-17, Type 1 interferon transcriptional pathways and neutrophil persistence genes associated with increased mortality from pneumococcal meningitis in adults: | [1]Emma CB Wall, [2]Jose Afonso Guerra-Assuncao, [3]Gabriele Pollara, [4]Cristina Venturini, [5]Veronica Mlowzowa, [6]Theresa Allain, [7]David Lalloo, [8]Mahdad Noursadeghi, [9]Jeremy S Brown, [10]Robert Heyderman [Full author list] | | DOI: 10.1101/490045
| meningitis [curation]; pneumococcal meningitis [curation] | 2018-12-07 |
| Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial | [1]Cissy Kityo, [2]Alexander J Szubert, [3]Abraham Siika, [4]Robert Heyderman, [5]Mutsa Bwakura-Dangarembizi, [6]Abbas Lugemwa, [7]Shalton Mwaringa, [8]Anna Griffiths, [9]Immaculate Nkanya, [10]Sheila Kabahenda, ... [Full author list] | PLOS MEDICINE [curation] | DOI: 10.1371/JOURNAL.PMED.1002706
PubMed: 30513108 | | 2018-12-04 |
| Brain MRI and cognitive function seven years after surviving an episode of severe acute malnutrition in a cohort of Malawian children | [1]Natasha Lelijveld, [2]Alhaji A Jalloh, [3]Samuel D Kampondeni, [4]Andrew Seal, [5]Jonathan C Wells, [6]Magdalena Goyheneix, [7]Emmanuel Chimwezi, [8]Macpherson Mallewa, [9]Moffat J Nyirenda, [10]Robert Heyderman, [11]Marko Kerac [Full author list] | Public Health Nutrition [curation] | DOI: 10.1017/S1368980018003282
PubMed: 30501662 | malnutrition [curation]; severe acute malnutrition [curation] | 2018-12-03 |
| High residual prevalence of vaccine serotype Streptococcus pneumoniae carriage 4 to 6 years after introduction of 13-valent pneumococcal conjugate vaccine in Malawi: a prospective serial cross-sectional study | [1]Todd D Swarthout, [2]Claudio Fronterre, [3]José Lourenço, [4]Uri Obolski, [5]Andrea Gori, [6]Naor Bar-Zeev, [7]Dean Everett, [8]Arox W Kamngona, [9]Thandie S Mwalukomo, [10]Andrew A Mataya, [11]Charles Mwansambo, [12]Marjory Banda, [13]Sunetra Gupta, [14]Peter Diggle, [15]Neil French, [16]Robert Heyderman [Full author list] | | DOI: 10.1101/445999
| Streptococcus pneumoniae [curation]; pneumococcal conjugate vaccine [curation] | 2018-10-26 |
| Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries | [1]Angela Loyse, [2]Jessica Burry, [3]Jennifer Cohn, [4]Nathan Ford, [5]Tom Chiller, [6]Isabela Ribeiro, [7]Sinata Koulla-Shiro, [8]Janneth Mghamba, [9]Angela Ramadhani, [10]Rose Nyirenda, ..., [33]Jeffrey D Klausner, [34]David R. Boulware, [35]Robert Heyderman, [36]David Lalloo, [37]Jeremy Day, ... [Full author list] | Lancet Infectious Diseases [curation] | DOI: 10.1016/S1473-3099(18)30493-6
PubMed: 30344084 | meningitis [curation]; infectious disease [curation]; cryptococcal meningitis [curation] | 2018-10-18 |
| Ischemic stroke as a complication of cryptococcal meningitis and immune reconstitution inflammatory syndrome: a case report | [1]Jayne Ellis, [2]Newton Kalata, [3]Elizabeth C Joekes, [4]Samuel Kampondeni, [5]Laura A Benjamin, [6]Thomas Harrison, [7]David G Lalloo, [8]Robert Heyderman [Full author list] | BMC Infectious Diseases [curation] | DOI: 10.1186/S12879-018-3386-0
PubMed: 30326861 | meningitis [curation]; immune reconstitution inflammatory syndrome [curation]; cryptococcal meningitis [curation] | 2018-10-16 |
| Effect of oral fluconazole 1200 mg/day on QT interval in African adults with HIV-associated cryptococcal meningitis | [1]Síle F Molloy, [2]John Bradley, [3]Natasha Karunaharan, [4]Muhammad Mputu, [5]Neil Stone, [6]Jacob Phulusa, [7]Chimwemwe Chawinga, [8]Kate Gaskell, [9]Dalitso Segula, [10]Damien Ming, [11]Mary Peirse, [12]Duncan Chanda, [13]Shabir Lakhi, [14]Angela Loyse, [15]Cecilia Kanyama, [16]Robert Heyderman, [17]Thomas Harrison [Full author list] | AIDS [curation] | DOI: 10.1097/QAD.0000000000001961
PubMed: 30102652 | meningitis [curation]; immunology [curation]; fluconazole [curation]; infectious disease [curation]; cryptococcal meningitis [curation] | 2018-09-24 |
| Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013 | [1]Antonia Ho, [2]Jane Mallewa, [3]Ingrid Peterson, [4]Miguel SanJoaquin, [5]Shikha Garg, [6]Naor Bar-Zeev, [7]Mavis Menyere, [8]Maaike Alaerts, [9]Gugulethu Mapurisa, [10]Moses Chilombe, [11]Mulinda Nyirenda, [12]David G Lalloo, [13]Camilla Rothe, [14]Marc-Alain Widdowson, [15]Meredith McMorrow, [16]Neil French, [17]Dean Everett, [18]Robert Heyderman [Full author list] | American Journal of Tropical Medicine and Hygiene [curation] | DOI: 10.4269/AJTMH.17-0905
PubMed: 30039785 | Malawi [curation]; parasitology [curation]; infectious disease [curation]; acute respiratory disease [curation] | 2018-09-01 |
| Impact of monovalent rotavirus vaccine on diarrhoea-associated post-neonatal infant mortality in rural communities in Malawi: a population-based birth cohort study | [1]Naor Bar-Zeev, [2]Carina King, [3]Tambosi Phiri, [4]James Beard, [5]Hazzie Mvula, [6]Amelia C Crampin, [7]Ellen Heinsbroek, [8]Sonia Lewycka, [9]Jacqueline E Tate, [10]Umesh Parashar, [11]Anthony Costello, [12]Charles Mwansambo, [13]Robert Heyderman, [14]Neil French, [15]Nigel A. Cunliffe [Full author list] | The Lancet Global Health [curation] | DOI: 10.1016/S2214-109X(18)30314-0
PubMed: 30103981 | Malawi [curation]; diarrhea [curation]; rotavirus vaccine [curation]; birth cohort [curation] | 2018-09-01 |
| Direct and possible indirect effects of vaccination on rotavirus hospitalisations among children in Malawi four years after programmatic introduction | [1]Aisleen Bennett, [2]L Pollock, [3]K C Jere, [4]Virginia E. Pitzer, [5]Umesh Parashar, [6]Jacqueline E Tate, [7]Robert Heyderman, [8]C Mwansambo, [9]N French, [10]O Nakagomi, [11]Miren Iturriza, [12]D Everett, [13]Nigel A. Cunliffe, [14]N Bar-Zeev, [15]VacSurv Consortium [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2018.04.030
PubMed: 29887320 | Malawi [curation]; hospitalization [curation]; molecular medicine [curation]; infectious disease [curation] | 2018-06-07 |
| Multiplex Real-Time PCR Detection of Intestinal Protozoa in HIV-Infected Children in Malawi, Enterocytozoon Bieneusi is Common and Associated with Gastrointestinal Complaints and May Delay BMI (Nutritional Status) Recovery. | [1]Minke H W Huibers, [2]Peter Moons, [3]Nelson Maseko, [4]Monfort B Gushu, [5]Oluwadamilola H Iwajomo, [6]Robert Heyderman, [7]Michael Boele van Hensbroek, [8]Eric A. T. Brienen, [9]Lisette van Lieshout, [10]Job C J Calis [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000001924
PubMed: 29762365 | Malawi [curation]; Enterocytozoon bieneusi [curation] | 2018-05-14 |
| Identifying Streptococcus pneumoniae genes associated with invasive disease using pangenome-based whole genome sequence typing | [1]Uri Obolski, [2]Andrea Gori, [3]Jose Lourenco, [4]Craig Thompson, [5]Robin Thompson, [6]Neil French, [7]Robert Heyderman, [8]Sunetra Gupta [Full author list] | | DOI: 10.1101/314666
| Streptococcus pneumoniae [curation]; invasive disease [curation] | 2018-05-04 |
| Epithelial control of colonisation byStreptococcus pneumoniaeat the human mucosal surface | [1]Caroline M Weight, [2]Cristina Venturini, [3]Sherin Pojar, [4]Simon Jochems, [5]Jesús Reiné, [6]Elissavet Nikolaou, [7]Carla Solórzano, [8]Mahdad Noursadeghi, [9]Jeremy S Brown, [10]Daniela M Ferreira, [11]Robert Heyderman [Full author list] | | DOI: 10.1101/281576
| | 2018-03-13 |
| Impact of Human Immunodeficiency Virus on the Burden and Severity of Influenza Illness in Malawian Adults: A Prospective Cohort and Parallel Case-Control Study | [1]Antonia Ho, [2]Stephen Aston, [3]Hannah Jary, [4]Tamara Mitchell, [5]Maaike Alaerts, [6]Mavis Menyere, [7]Jane Mallewa, [8]Mulinda Nyirenda, [9]Dean Everett, [10]Robert Heyderman, [11]Neil French [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIX903
PubMed: 29045699 | | 2018-03-01 |
| Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa. | [1]Síle F Molloy, [2]Cecilia Kanyama, [3]Robert Heyderman, [4]Angela Loyse, [5]Charles Kouanfack, [6]Duncan Chanda, [7]Sayoki Mfinanga, [8]Elvis Temfack, [9]Shabir Lakhi, [10]Sokoine Lesikari, ... [Full author list] | The New England Journal of Medicine [curation] | DOI: 10.1056/NEJMOA1710922
PubMed: 29539274 | meningitis [curation]; cryptococcal meningitis [curation] | 2018-03-01 |
| Osmotic therapies added to antibiotics for acute bacterial meningitis | [1]Emma C Wall, [2]Katherine Mb Ajdukiewicz, [3]Hanna Bergman, [4]Robert Heyderman, [5]Paul Garner [Full author list] | Cochrane Database of Systematic Reviews [curation] | DOI: 10.1002/14651858.CD008806.PUB3
PubMed: 29405037 | antibiotic [curation]; glycerol [curation]; bacterial meningitis [curation]; osmotic diuretics [curation] | 2018-02-06 |
| Predictive value of C-reactive protein for tuberculosis, bloodstream infection or death among HIV-infected individuals with chronic, non-specific symptoms and negative sputum smear microscopy | [1]Richard Bedell, [2]Monique van Lettow, [3]Christopher Meaney, [4]Elizabeth L. Corbett, [5]Adrienne K Chan, [6]Robert Heyderman, [7]Suzanne T Anderson, [8]Ann Åkesson, [9]Moses Kelly Kumwenda, [10]Rony Zachariah, [11]Anthony D Harries, [12]Andrew R Ramsay [Full author list] | Tropical Medicine and International Health [curation] | DOI: 10.1111/TMI.13025
PubMed: 29243878 | sputum [curation] | 2018-01-04 |
| Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults | [1]Chikondi Peno, [2]Dominic H Banda, [3]Ndaru Jambo, [4]Anstead M Kankwatira, [5]Rose D Malamba, [6]Theresa J Allain, [7]Daniela M Ferreira, [8]Robert Heyderman, [9]David G Russell, [10]Henry Mwandumba, [11]Kondwani C Jambo [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2017.10.013
PubMed: 29197600 | Streptococcus pneumoniae [curation] | 2017-11-29 |
| Emergence of double- and triple-gene reassortant G1P[8] rotaviruses possessing a DS-1-like backbone post rotavirus vaccine introduction in Malawi | [1]Khuzwayo C. Jere, [2]Chrispin Chaguza, [3]Naor Bar-Zeev, [4]Jenna Lowe, [5]Chikondi Peno, [6]Benjamin Kumwenda, [7]Osamu Nakagomi, [8]Jacqueline E Tate, [9]Umesh Parashar, [10]Robert Heyderman, [11]Neil French, [12]Nigel A. Cunliffe, [13]Miren Iturriza-Gómara [Full author list] | Journal of Virology [curation] | DOI: 10.1128/JVI.01246-17
PubMed: 29142125 | Malawi [curation]; rotavirus vaccine [curation] | 2017-11-15 |
| Goal directed therapy for suspected acute bacterial meningitis in adults and adolescents in sub-Saharan Africa | [1]Emma C Wall, [2]Mavuto Mukaka, [3]Brigitte Denis, [4]Veronica S Mlozowa, [5]Malango Msukwa, [6]Khumbo Kasambala, [7]Mulinda Nyrienda, [8]Theresa J Allain, [9]Brian Faragher, [10]Robert Heyderman, [11]David Lalloo [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0186687
PubMed: 29077720 | meningitis [curation]; Sub-Saharan Africa [curation]; bacterial meningitis [curation] | 2017-10-27 |
| HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy | [1]Kondwani C Jambo, [2]Dumizulu L Tembo, [3]Arox W Kamng'ona, [4]Patrick Musicha, [5]Dominic H Banda, [6]Anstead M Kankwatira, [7]Rose D Malamba, [8]Theresa J Allain, [9]Robert Heyderman, [10]David G Russell, [11]Henry Mwandumba [Full author list] | ERJ open research [curation] | DOI: 10.1183/23120541.00097-2017
PubMed: 29255717 | | 2017-10-01 |
| The economic impact of childhood acute gastroenteritis on Malawian families and the healthcare system | [1]Nathaniel Hendrix, [2]Naor Bar-Zeev, [3]Deborah Atherly, [4]Jean Chikafa, [5]Hazzie Mvula, [6]Richard Wachepa, [7]Amelia Crampin, [8]Themba Mhango, [9]Charles Mwansambo, [10]Robert Heyderman, [11]Neil French, [12]Nigel A. Cunliffe, [13]Clint Pecenka, [14]VacSurv Consortium [Full author list] | BMJ Open [curation] | DOI: 10.1136/BMJOPEN-2017-017347
PubMed: 28871025 | gastroenteritis [curation] | 2017-09-03 |
| The Role of Human Immunodeficiency Virus-Associated Vasculopathy in the Etiology of Stroke | [1]Laura A Benjamin, [2]Theresa J Allain, [3]Henry Mzinganjira, [4]Myles D Connor, [5]Colin Smith, [6]Sebastian Lucas, [7]Elizabeth Joekes, [8]Sam Kampondeni, [9]Karen Chetcuti, [10]Ian Turnbull, [11]Mark Hopkins, [12]Steve Kamiza, [13]Elizabeth Jane Wiley Warren Corbett, [14]Robert Heyderman, [15]Tom Solomon [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIX340
PubMed: 28931222 | | 2017-09-01 |
| The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26–27 October 2016, | [1]James E. Meiring, [2]Malick Gibani, [3]Buddha Basnyat, [4]Adwoa D. Bentsi-Enchill, [5]John Clemens, [6]Thomas C. Darton, [7]Kashmira Date, [8]Gordon Dougan, [9]Denise Garrett, [10]Bradford D Gessner, [11]Melita A. Gordon, [12]Robert Heyderman, [13]Joachim Hombach, [14]Karen L Kotloff, ... [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2017.08.001
PubMed: 28802757 | molecular medicine [curation]; typhoid vaccine [curation]; infectious disease [curation] | 2017-09-01 |
| Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study | [1]Patrick Musicha, [2]Jen Cornick, [3]Naor Bar-Zeev, [4]Neil French, [5]Clemens Masesa, [6]Brigitte Denis, [7]Neil Kennedy, [8]Jane Mallewa, [9]Melita A. Gordon, [10]Chisomo L Msefula, [11]Robert Heyderman, [12]Dean B Everett, [13]Nicholas A Feasey [Full author list] | Lancet Infectious Diseases [curation] | DOI: 10.1016/S1473-3099(17)30394-8
PubMed: 28818544 | Malawi [curation] | 2017-08-14 |
| Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi | [1]Chrispin Chaguza, [2]Jen Cornick, [3]Cheryl P Andam, [4]Rebecca A Gladstone, [5]Maaike Alaerts, [6]Patrick Musicha, [7]Chikondi PENO, [8]Naor Bar-Zeev, [9]Arox W Kamng'ona, [10]Anmol M Kiran, [11]Chisomo L Msefula, [12]Lesley McGee, [13]Robert F Breiman, [14]Aras Kadioglu, [15]Neil French, [16]Robert Heyderman, [17]William P. Hanage, [18]Stephen D Bentley, [19]Dean B Everett [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2017.07.009
PubMed: 28711389 | Malawi [curation]; population genetics [curation]; antibiotic resistance [curation] | 2017-07-12 |
| The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys | [1]Thomas C. Darton, [2]James E Meiring, [3]Susan Tonks, [4]Arifuzzaman Khan, [5]Farhana Khanam, [6]Mila Shakya, [7]Deus Thindwa, [8]Stephen Baker, [9]Buddha Basnyat, [10]John Clemens, ..., [13]Sarah J Dunstan, [14]Melita A. Gordon, [15]Robert Heyderman, [16]Kat Holt, [17]Virginia E. Pitzer, ... [Full author list] | BMJ Open [curation] | DOI: 10.1136/BMJOPEN-2017-016283
PubMed: 28674145 | Nepal [curation]; Bangladesh [curation]; Malawi [curation]; study protocol [curation] | 2017-07-02 |
| Early Antiretroviral Therapy Initiation and Mortality Among Infants Diagnosed With HIV in the First 12 Weeks of Life: Experiences From Kinshasa, DR Congo and Blantyre, Malawi | [1]Anna D Sheahan, [2]Lydia Feinstein, [3]Queen Dube, [4]Andrew Edmonds, [5]Chawanangwa Mahebere Chirambo, [6]Emily R Smith, [7]Frieda Behets, [8]Robert Heyderman, [9]Annelies Van Rie [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000001539
PubMed: 28060044 | Malawi [curation]; Kinshasa [curation]; child mortality [curation] | 2017-07-01 |
| Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children | [1]Tonney S Nyirenda, [2]James T Nyirenda, [3]Dumizulu L Tembo, [4]Janet Storm, [5]Queen Dube, [6]Chisomo L Msefula, [7]Kondwani C Jambo, [8]Henry Mwandumba, [9]Robert Heyderman, [10]Melita A. Gordon, [11]Wilson L Mandala [Full author list] | Clinical and Vaccine Immunology [curation] | DOI: 10.1128/CVI.00057-17
PubMed: 28515136 | Plasmodium falciparum [curation] | 2017-05-17 |
| Long-term effects of severe acute malnutrition on lung function in Malawian children: a cohort study | [1]Natasha Lelijveld, [2]Marko Kerac, [3]Andrew Seal, [4]Emmanuel Chimwezi, [5]Jonathan Wells, [6]Robert Heyderman, [7]Moffat Nyirenda, [8]Janet Stocks, [9]Jane Kirkby [Full author list] | European Respiratory Journal [curation] | DOI: 10.1183/13993003.01301-2016
PubMed: 28381429 | malnutrition [curation]; severe acute malnutrition [curation] | 2017-04-05 |
| Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting | [1]Patrick Musicha, [2]Nicholas A Feasey, [3]Amy K Cain, [4]Teemu Kallonen, [5]Chrispin Chaguza, [6]Chikondi Peno, [7]Margaret Khonga, [8]Sarah Thompson, [9]Katherine J Gray, [10]Alison E Mather, [11]Robert Heyderman, [12]Dean B Everett, [13]Nicholas Thomson, [14]Chisomo L Msefula [Full author list] | Journal of Antimicrobial Chemotherapy [curation] | DOI: 10.1093/JAC/DKX058
PubMed: 28333330 | Escherichia coli [curation] | 2017-03-05 |
| Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings. | [1]Nicholas A Feasey, [2]James Hadfield, [3]Karen H Keddy, [4]Timothy J Dallman, [5]Jan Jacobs, [6]Xiangyu Deng, [7]Paul Wigley, [8]Lars Barquist, [9]Gemma C Langridge, [10]Theresa Feltwell, ..., [42]Robert A Kingsley, [43]Julian Parkhill, [44]Robert Heyderman, [45]Gordon Dougan, [46]Melita A. Gordon, ... [Full author list] | Nature Genetics [curation] | DOI: 10.1038/NG0417-651C
PubMed: 28358127 | Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings [curation]; Salmonella enteritidis [curation]; invasive disease [curation] | 2017-03-01 |
| The Treatment of Possible Severe Infection in Infants: An Open Randomized Safety Trial of Parenteral Benzylpenicillin and Gentamicin Versus Ceftriaxone in Infants <60 days of Age in Malawi | [1]Elizabeth M Molyneux, [2]Queen Dube, [3]Francis Banda, [4]Msandeni Chiume, [5]Isaac Singini, [6]Macpherson Mallewa, [7]Edward C Schwalbe, [8]Robert Heyderman [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000001576
PubMed: 28263245 | Malawi [curation]; benzylpenicillin [curation]; ceftriaxone [curation]; gentamicin [curation] | 2017-02-28 |
| Age Related Patterns of Disease and Mortality in Hospitalised Adults in Malawi | [1]Theresa J Allain, [2]Stephen Aston, [3]Gugulethu Mapurisa, [4]Thokozani N Ganiza, [5]Ndaziona P Banda, [6]Servace Sakala, [7]Andrew Gonani, [8]Robert Heyderman, [9]Ingrid Peterson [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0168368
PubMed: 28099438 | Malawi [curation]; hospitalization [curation] | 2017-01-18 |
| The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1. | [1]Jen Cornick, [2]Ozlem Tastan Bishop, [3]Feyruz Yalcin, [4]Anmol M Kiran, [5]Benjamin Kumwenda, [6]Chrispin Chaguza, [7]Shanil Govindpershad, [8]Sani Ousmane, [9]Madikay Senghore, [10]Mignon du Plessis, ..., [20]Neil French, [21]Keith P. Klugman, [22]Robert Heyderman, [23]Mark Alderson, [24]Dean B Everett, ... [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2016.12.037
PubMed: 28081968 | | 2017-01-09 |
| Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population | [1]Daniel Carr, [2]Stephane Bourgeois, [3]Mas Chaponda, [4]Louise Y Takeshita, [5]Andrew P Morris, [6]Elena M Cornejo Castro, [7]Ana Alfirevic, [8]Andrew R Jones, [9]Daniel J. Rigden, [10]Sam Haldenby, [11]Saye Khoo, [12]David Lalloo, [13]Robert Heyderman, [14]Collet Dandara, [15]Elizabeth Kampira, ... [Full author list] | Journal of Antimicrobial Chemotherapy [curation] | DOI: 10.1093/JAC/DKW545
PubMed: 28062682 | Sub-Saharan Africa [curation]; nevirapine [curation]; genome-wide association study [curation] | 2017-01-06 |
| Challenges in reducing group B Streptococcus disease in African settings | [1]Yo Nishihara, [2]Ziyaad Dangor, [3]Neil French, [4]Shabir A. Madhi, [5]Robert Heyderman [Full author list] | Archives of Disease in Childhood [curation] | DOI: 10.1136/ARCHDISCHILD-2016-311419
PubMed: 27831912 | streptococcal infection [curation] | 2017-01-01 |
| Prediction of Outcome From Adult Bacterial Meningitis in a High-HIV-Seroprevalence, Resource-Poor Setting Using the Malawi Adult Meningitis Score (MAMS). | [1]Emma C Wall, [2]Mavuto Mukaka, [3]Matthew Scarborough, [4]Katherine M A Ajdukiewicz, [5]Katharine E Cartwright, [6]Mulinda Nyirenda, [7]Brigitte Denis, [8]Theresa J Allain, [9]Brian Faragher, [10]David Lalloo, [11]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIW779
PubMed: 27927860 | Malawi [curation]; meningitis [curation]; seroprevalence [curation]; bacterial meningitis [curation] | 2016-12-07 |
| Understanding pneumococcal serotype 1 biology through population genomic analysis | [1]Chrispin Chaguza, [2]Jen Cornick, [3]Simon R Harris, [4]Cheryl P Andam, [5]Laura Bricio-Moreno, [6]Marie Yang, [7]Feyruz Yalcin, [8]Sani Ousmane, [9]Shanil Govindpersad, [10]Madikay Senghore, ..., [22]Martin Antonio, [23]Anne von Gottberg, [24]Robert Heyderman, [25]Neil French, [26]Aras Kadioglu, ... [Full author list] | BMC Infectious Diseases [curation] | DOI: 10.1186/S12879-016-1987-Z
PubMed: 27821148 | | 2016-11-08 |
| Performance of HIV Rapid Tests Among Breastfeeding, Malawian Infants | [1]Emily R Smith, [2]Anna D Sheahan, [3]Robert Heyderman, [4]William C. Miller, [5]Stephanie B Wheeler, [6]Michael Hudgens, [7]Julie A E Nelson, [8]Queen Dube, [9]Annelies Van Rie [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000001384
PubMed: 27798549 | breastfeeding [curation] | 2016-10-27 |
| Recombination in Streptococcus pneumoniae Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule | [1]Chrispin Chaguza, [2]Cheryl P Andam, [3]Simon R Harris, [4]Jen Cornick, [5]Marie Yang, [6]Laura Bricio-Moreno, [7]Arox W Kamng'ona, [8]Julian Parkhill, [9]Neil French, [10]Robert Heyderman, [11]Aras Kadioglu, [12]Dean B Everett, [13]Stephen D Bentley, [14]William P. Hanage [Full author list] | mBio [curation] | DOI: 10.1128/MBIO.01053-16
PubMed: 27677790 | polysaccharide [curation]; Streptococcus pneumoniae [curation] | 2016-09-27 |
| Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa | [1]International Typhoid Consortium, [2]Vanessa N.L. Wong, [3]Kat Holt, [4]Chinyere K. Okoro, [5]Stephen Baker, [6]Derek J Pickard, [7]Florian Marks, [8]Andrew J. Page, [9]Grace Olanipekun, [10]Huda Munir, ..., [18]Robert F Breiman, [19]Melita A. Gordon, [20]Robert Heyderman, [21]Jan Jacobs, [22]Octavie Lunguya, ... [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0004781
PubMed: 27657909 | West Africa [curation] | 2016-09-22 |
| Respiratory Virus-Associated Severe Acute Respiratory Illness and Viral Clustering in Malawian Children in a Setting With a High Prevalence of HIV Infection, Malaria, and Malnutrition | [1]Ingrid Peterson, [2]Naor Bar-Zeev, [3]Neil Kennedy, [4]Antonia Ho, [5]Laura Newberry, [6]Miguel A SanJoaquin, [7]Mavis Menyere, [8]Maaike Alaerts, [9]Gugulethu Mapurisa, [10]Moses Chilombe, ..., [19]Neil French, [20]Dean Everett, [21]Robert Heyderman [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIW426
PubMed: 27630199 | malaria [curation]; malnutrition [curation]; acute respiratory disease [curation] | 2016-09-13 |
| HIV coinfection influences the inflammatory response but not the outcome of cerebral malaria in Malawian children | [1]Emmie W Mbale, [2]Christopher A Moxon, [3]Mavuto Mukaka, [4]Maganizo Chagomerana, [5]Simon Glover, [6]Ngawina Chisala, [7]Sofia Omar, [8]Malcolm Molyneux, [9]Karl Seydel, [10]Alister G Craig, [11]Terrie Taylor, [12]Robert Heyderman, [13]Macpherson Mallewa [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2016.05.012
PubMed: 27311750 | malaria [curation]; infection [curation]; cerebral malaria [curation]; human immunodeficiency virus infectious disease [curation]; RNA virus infectious disease [curation]; Retroviridae infectious disease [curation] | 2016-09-01 |
| Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings | [1]Nicholas A Feasey, [2]James Hadfield, [3]Karen H Keddy, [4]Timothy J Dallman, [5]Jan Jacobs, [6]Xiangyu Deng, [7]Paul Wigley, [8]Lars Barquist, [9]Gemma C Langridge, [10]Theresa Feltwell, ..., [42]Robert A Kingsley, [43]Julian Parkhill, [44]Robert Heyderman, [45]Gordon Dougan, [46]Melita A. Gordon, ... [Full author list] | Nature Genetics [curation] | DOI: 10.1038/NG.3644
PubMed: 27548315 | Salmonella enteritidis [curation]; invasive disease [curation] | 2016-08-22 |
| Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study | [1]Jamie Rylance, [2]Anstead Kankwatira, [3]David E Nelson, [4]Evelyn Toh, [5]Richard B Day, [6]Huaiying Lin, [7]Xiang Gao, [8]Qunfeng Dong, [9]Erica Sodergren, [10]George Weinstock, [11]Robert Heyderman, [12]Homer L Twigg, [13]Siamon Gordon [Full author list] | BMC Microbiology [curation] | DOI: 10.1186/S12866-016-0803-7
PubMed: 27514621 | Malawi [curation]; air pollution [curation]; microbiome [curation] | 2016-08-11 |
| British HIV Association Guidelines on the Use of Vaccines in HIV-Positive Adults 2015. | [1]Anna Maria Geretti, [2]Gary Brook, [3]Claire Cameron, [4]David Chadwick, [5]Neil French, [6]Robert Heyderman, [7]Antonia Ho, [8]Michael Hunter, [9]Shamez Ladhani, [10]Mark Lawton, [11]Eithne MacMahon, [12]John McSorley, [13]Anton Pozniak, [14]Alison Rodger [Full author list] | HIV Medicine [curation] | DOI: 10.1111/HIV.12424
PubMed: 27568789 | | 2016-08-01 |
| Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study. | [1]Natasha Lelijveld, [2]Andrew Seal, [3]Jonathan Wells, [4]Jane Kirkby, [5]Charles Opondo, [6]Emmanuel Chimwezi, [7]James Bunn, [8]Robert Bandsma, [9]Robert Heyderman, [10]Moffat Nyirenda, [11]Marko Kerac [Full author list] | The Lancet Global Health [curation] | DOI: 10.1016/S2214-109X(16)30133-4
PubMed: 27470174 | malnutrition [curation]; severe acute malnutrition [curation] | 2016-07-25 |
| Unstructured treatment interruption: an important risk factor for arterial stiffness in adult Malawian patients with antiretroviral treatment | [1]Ingrid Peterson, [2]Damien Ming, [3]Christine Kelly, [4]Kennedy Malisita, [5]J Mallewa, [6]Henry Mwandumba, [7]David Lalloo, [8]Robert Heyderman [Full author list] | AIDS [curation] | DOI: 10.1097/QAD.0000000000001198
PubMed: 27428743 | risk factor [curation]; anti-retroviral agent [curation] | 2016-07-13 |
| Arterial ischemic stroke in HIV: Defining and classifying etiology for research studies | [1]Laura A Benjamin, [2]Alan Bryer, [3]Sebastian Lucas, [4]Alan Stanley, [5]Theresa J Allain, [6]Elizabeth Joekes, [7]Hedley C Emsley, [8]Ian Turnbull, [9]Colin Downey, [10]Cheng-Hock Toh, [11]Kevin Brown, [12]David Brown, [13]Catherine Ison, [14]Colin Smith, [15]Elizabeth L Corbett, [16]Avindra Nath, [17]Robert Heyderman, [18]Myles D Connor, [19]Tom Solomon [Full author list] | Neurology(R) neuroimmunology & neuroinflammation [curation] | DOI: 10.1212/NXI.0000000000000254
PubMed: 27386505 | | 2016-06-30 |
| Public engagement in Malawi through a health-talk radio programme 'Umoyo nkukambirana': A mixed-methods evaluation | [1]Deborah Nyirenda, [2]Tamara Chipasula Makawa, [3]Greyson Chapita, [4]Chisomo Mdalla, [5]Mzati Nkolokosa, [6]Thomasena O'byrne, [7]Robert Heyderman, [8]Nicola Desmond [Full author list] | Public Understanding of Science [curation] | DOI: 10.1177/0963662516656110
PubMed: 27365364 | Malawi [curation] | 2016-06-30 |
| Re: Moxifloxacin should not be discounted in the treatment of bacterial meningitis | [1]Fiona McGill, [2]Robert Heyderman, [3]Tom Solomon [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2016.05.005
PubMed: 27268026 | moxifloxacin [curation] | 2016-06-03 |
| Acute bacterial meningitis in adults. | [1]Fiona McGill, [2]Robert Heyderman, [3]Stavros Panagiotou, [4]Allan R Tunkel, [5]Tom Solomon [Full author list] | The Lancet [curation] | DOI: 10.1016/S0140-6736(16)30654-7
PubMed: 27265346 | meningitis [curation]; bacterial meningitis [curation] | 2016-06-02 |
| Predictors of Uptake and Timeliness of Newly Introduced Pneumococcal and Rotavirus Vaccines, and of Measles Vaccine in Rural Malawi: A Population Cohort Study | [1]Hazzie Mvula, [2]Ellen Heinsbroek, [3]Menard Chihana, [4]Amelia Crampin, [5]Storn Kabuluzi, [6]Geoffrey Chirwa, [7]Charles Mwansambo, [8]Anthony Costello, [9]Nigel A Cunliffe, [10]Robert Heyderman, [11]Neil French, [12]Naor Bar-Zeev, [13]VacSurv Consortium [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0154997
PubMed: 27152612 | Malawi [curation]; measles [curation]; rotavirus vaccine [curation]; measles vaccine [curation] | 2016-05-06 |
| Cost-Effectiveness of Monovalent Rotavirus Vaccination of Infants in Malawi: A Postintroduction Analysis Using Individual Patient-Level Costing Data | [1]Naor Bar-Zeev, [2]Jacqueline E Tate, [3]Clint Pecenka, [4]Jean Chikafa, [5]Hazzie Mvula, [6]Richard Wachepa, [7]Charles Mwansambo, [8]Themba Mhango, [9]Geoffrey Chirwa, [10]Amelia Crampin, [11]Umesh Parashar, [12]Anthony Costello, [13]Robert Heyderman, [14]Neil French, [15]Deborah E Atherly, [16]Nigel A. Cunliffe, [17]VACSURV Consortium [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV1025
PubMed: 27059360 | Malawi [curation] | 2016-05-01 |
| Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses | [1]Naor Bar-Zeev, [2]Khuzwayo C. Jere, [3]Aisleen Bennett, [4]Louisa Pollock, [5]Jacqueline E Tate, [6]Osamu Nakagomi, [7]Miren Iturriza-Gómara, [8]Anthony Costello, [9]Charles Mwansambo, [10]Umesh Parashar, [11]Robert Heyderman, [12]Neil French, [13]Nigel A. Cunliffe, [14]Vaccine Effectiveness and Disease Surveillance Programme, Malawi (VACSURV) Consortium [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV1183
PubMed: 27059359 | Malawi [curation]; vaccine [curation]; urbanization [curation]; urban ecology [curation] | 2016-05-01 |
| Corrigendum to "The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent Adults" [J Infect 72 (2016) 405-438]. | [1]F McGill, [2]Robert Heyderman, [3]Benedict D. Michael, [4]S Defres, [5]Nick J. Beeching, [6]R Borrow, [7]L Glennie, [8]O Gaillemin, [9]D Wyncoll, [10]E Kaczmarski, [11]S Nadel, [12]Guy E. Thwaites, [13]J Cohen, [14]N W S Davies, [15]A Miller, [16]Andrew Rhodes, [17]R Read, [18]Tom Solomon [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2016.04.001
PubMed: 27085199 | meningitis [curation]; sepsis [curation]; The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults. [curation] | 2016-04-12 |
| Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580. | [1]Larissa A Singletary, [2]Joyce E. Karlinsey, [3]Stephen J Libby, [4]Jason P. Mooney, [5]Kristen L Lokken, [6]Renée M Tsolis, [7]Mariana Xavier Byndloss, [8]Lauren A Hirao, [9]Christopher A Gaulke, [10]Robert W Crawford, [11]Satya Dandekar, [12]Robert A Kingsley, [13]Chisomo L Msefula, [14]Robert Heyderman, [15]Ferric C Fang [Full author list] | mBio [curation] | DOI: 10.1128/MBIO.02265-15
PubMed: 26933058 | Salmonella enterica [curation]; multicellularity [curation] | 2016-03-01 |
| Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial | [1]Robert Heyderman, [2]Shabir A. Madhi, [3]Neil French, [4]Clare L. Cutland, [5]Bagrey Ngwira, [6]Doris Kayambo, [7]Robert Mboizi, [8]Anthonet Koen, [9]Lisa Jose, [10]Morounfolu Olugbosi, [11]Frederik Wittke, [12]Karen Slobod, [13]Peter M Dull [Full author list] | Lancet Infectious Diseases [curation] | DOI: 10.1016/S1473-3099(15)00484-3
PubMed: 26869376 | multicenter clinical trial [curation]; phase II clinical trial [curation]; pregnant person [curation] | 2016-02-08 |
| The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults | [1]F McGill, [2]Robert Heyderman, [3]Benedict D. Michael, [4]S Defres, [5]Nick J. Beeching, [6]R Borrow, [7]L Glennie, [8]O Gaillemin, [9]D Wyncoll, [10]E Kaczmarski, [11]S Nadel, [12]Guy E. Thwaites, [13]J Cohen, [14]N W S Davies, [15]A Miller, [16]Andrew Rhodes, [17]Robert Read, [18]Tom Solomon [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2016.01.007
PubMed: 26845731 | meningitis [curation]; sepsis [curation] | 2016-02-02 |
| Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis | [1]Justin Beardsley, [2]Marcel Wolbers, [3]Freddie Kibengo, [4]Abu-Baker M Ggayi, [5]Anatoli Kamali, [6]Ngo Thi Kim Cuc, [7]Tran Quang Binh, [8]Nguyen Van Vinh Chau, [9]Jeremy Farrar, [10]Laura Merson, ..., [19]Watthanapong Supphamongkholchaikul, [20]Adrienne K Chan, [21]Robert Heyderman, [22]Edson Mwinjiwa, [23]Joep J van Oosterhout, ... [Full author list] | The New England Journal of Medicine [curation] | DOI: 10.1056/NEJMOA1509024
PubMed: 26863355 | meningitis [curation]; dexamethasone [curation] | 2016-02-01 |
| Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial | [1]Ayub Mpoya, [2]Sarah Kiguli, [3]Peter Olupot-Olupot, [4]Robert O Opoka, [5]Charles Engoru, [6]Macpherson Mallewa, [7]Yami Chimalizeni, [8]Neil Kennedy, [9]Dorothy Kyeyune, [10]Benjamin Wabwire, ..., [13]Britta C Urban, [14]Michael Boele von Hensbroek, [15]Robert Heyderman, [16]Margaret Thomason, [17]Sophie Uyoga, ... [Full author list] | Trials [curation] | DOI: 10.1186/S13063-015-1112-4
PubMed: 26715196 | study protocol [curation] | 2015-12-29 |
| HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: A case-control study | [1]Laura A Benjamin, [2]Elizabeth Jane Wiley Warren Corbett, [3]Myles D Connor, [4]Henry Mzinganjira, [5]Sam Kampondeni, [6]Augustine Choko, [7]Mark Hopkins, [8]Hedley C Emsley, [9]Alan Bryer, [10]Brian Faragher, [11]Robert Heyderman, [12]Theresa J Allain, [13]Tom Solomon [Full author list] | Neurology [curation] | DOI: 10.1212/WNL.0000000000002278
PubMed: 26683649 | anti-retroviral agent [curation]; hypertension [curation] | 2015-12-18 |
| Erratum for Kulohoma et al., Comparative genomic analysis of meningitis- and bacteremia-causing pneumococci identifies a common core genome | [1]Benard Kulohoma, [2]Jen Cornick, [3]Chrispin Chaguza, [4]Feyruz Yalcin, [5]Simon R Harris, [6]Katherine J Gray, [7]Anmol M Kiran, [8]Elizabeth Molyneux, [9]Neil French, [10]Julian Parkhill, [11]E Brian Faragher, [12]Dean B Everett, [13]Stephen D Bentley, [14]Robert Heyderman [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.01156-15
PubMed: 26556879 | meningitis [curation] | 2015-12-01 |
| Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis | [1]Catriona John Waitt, [2]Peter Banda, [3]Sarah Glennie, [4]Beate Kampmann, [5]Stephen Squire, [6]Munir Pirmohamed, [7]Robert Heyderman [Full author list] | BMC Infectious Diseases [curation] | DOI: 10.1186/S12879-015-1274-4
PubMed: 26567164 | tuberculosis [curation]; pulmonary tuberculosis [curation] | 2015-11-13 |
| Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014. | [1]Nicholas A Feasey, [2]Clemens Masesa, [3]Chikondi Jassi, [4]E Brian Faragher, [5]Jane Mallewa, [6]Macpherson Mallewa, [7]Calman A MacLennan, [8]Chisomo Msefula, [9]Robert Heyderman, [10]Melita A. Gordon [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV691
PubMed: 26449953 | Malawi [curation]; multiple drug resistance [curation] | 2015-11-01 |
| A Perspective on Invasive Salmonella Disease in Africa | [1]John Crump, [2]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV709
PubMed: 26449937 | | 2015-11-01 |
| Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi | [1]Virginia E. Pitzer, [2]Nicholas A Feasey, [3]Chisomo L Msefula, [4]Jane Mallewa, [5]Neil Kennedy, [6]Queen Dube, [7]Brigitte Denis, [8]Melita A. Gordon, [9]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV710
PubMed: 26449939 | Malawi [curation]; typhoid fever [curation] | 2015-11-01 |
| Invasive Discussed in Africa Consensus Meeting 2014, Blantyre, Malawi | [1]Robert Heyderman, [2]John A. Crump [Full author list] | Emerging Infectious Diseases [curation] | DOI: 10.3201/EID2111.150624
| Malawi [curation] | 2015-11-01 |
| Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers | [1]Jamie Rylance, [2]Chikondi Chimpini, [3]Sean Semple, [4]David G Russell, [5]Malcolm J. Jackson, [6]Robert Heyderman, [7]Siamon Gordon [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0138762
PubMed: 26406307 | air pollution [curation] | 2015-09-25 |
| Methodological challenges in measuring vaccine effectiveness using population cohorts in low resource settings | [1]C King, [2]J Beard, [3]Amelia Crampin, [4]A Costello, [5]C Mwansambo, [6]Nigel A. Cunliffe, [7]Robert Heyderman, [8]N French, [9]Naor Bar-Zeev, [10]VacSurv Consortium [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2015.07.062
PubMed: 26235370 | epidemiological method [curation]; biomedical investigative technique [curation] | 2015-09-11 |
| Phenotypic Correlates of HIV-1 Macrophage Tropism | [1]Kathryn T Arrildt, [2]Celia C LaBranche, [3]Sarah B Joseph, [4]Elena N Dukhovlinova, [5]William D Graham, [6]Li-Hua Ping, [7]Gretja Schnell, [8]Christa B Sturdevant, [9]Laura P Kincer, [10]Macpherson Mallewa, [11]Robert Heyderman, [12]Annelies Van Rie, [13]Myron S. Cohen, [14]Serena Spudich, [15]Richard W Price, [16]David C. Montefiori, [17]Ronald Swanstrom [Full author list] | Journal of Virology [curation] | DOI: 10.1128/JVI.00946-15
PubMed: 26339058 | HIV [curation]; macrophage [curation] | 2015-09-02 |
| Study protocol: the effects of air pollution exposure and chronic respiratory disease on pneumonia risk in urban Malawian adults--the Acute Infection of the Respiratory Tract Study (The AIR Study) | [1]Hannah Jary, [2]Jane Mallewa, [3]Makandwe Nyirenda, [4]Brian Faragher, [5]Robert Heyderman, [6]Ingrid Peterson, [7]Siamon Gordon, [8]Kevin Mortimer [Full author list] | BMC Pulmonary Medicine [curation] | DOI: 10.1186/S12890-015-0090-3
PubMed: 26286032 | air pollution [curation]; urbanization [curation]; respiratory disease [curation]; study protocol [curation] | 2015-08-20 |
| Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae | [1]Jen Cornick, [2]Chrispin Chaguza, [3]Simon R Harris, [4]Feyruz Yalcin, [5]Madikay Senghore, [6]Anmol M Kiran, [7]Shanil Govindpershad, [8]Sani Ousmane, [9]Mignon du Plessis, [10]Gerd Pluschke, ..., [17]Neil French, [18]Keith P. Klugman, [19]Robert Heyderman, [20]Stephen D Bentley, [21]Dean B Everett, ... [Full author list] | Microbial genomics [curation] | DOI: 10.1099/MGEN.0.000027
PubMed: 28348812 | Streptococcus pneumoniae [curation] | 2015-08-11 |
| Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome | [1]Benard Kulohoma, [2]Jen Cornick, [3]Chrispin Chaguza, [4]Feyruz Yalcin, [5]Simon R Harris, [6]Katherine J Gray, [7]Anmol M Kiran, [8]Elizabeth Molyneux, [9]Neil French, [10]Julian Parkhill, [11]E Brian Faragher, [12]Dean B Everett, [13]Stephen D Bentley, [14]Robert Heyderman [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.00814-15
PubMed: 26259813 | meningitis [curation] | 2015-08-10 |
| Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi | [1]Nicholas A Feasey, [2]Dean Everett, [3]E Brian Faragher, [4]Arantxa Roca-Feltrer, [5]Arthur Kang'ombe, [6]Brigitte Denis, [7]Marko Kerac, [8]Elizabeth Molyneux, [9]Malcolm Molyneux, [10]Andreas Jahn, [11]Melita A. Gordon, [12]Robert Heyderman [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0003979
PubMed: 26230258 | Malawi [curation]; malaria [curation]; malnutrition [curation] | 2015-07-31 |
| Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding | [1]C A Moxon, [2]N V Chisala, [3]R Mzikamanda, [4]I MacCormick, [5]S Harding, [6]C Downey, [7]M Molyneux, [8]K B Seydel, [9]T E Taylor, [10]Robert Heyderman, [11]C-H Toh [Full author list] | Journal of Thrombosis and Haemostasis [curation] | DOI: 10.1111/JTH.13060
PubMed: 26186686 | malaria [curation]; thrombosis [curation]; disseminated intravascular coagulation [curation]; cerebral malaria [curation] | 2015-07-17 |
| High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children | [1]Arox W Kamng'ona, [2]Jason Hinds, [3]Naor Bar-Zeev, [4]Katherine A Gould, [5]Chrispin Chaguza, [6]Chisomo Msefula, [7]Jen Cornick, [8]Benard Kulohoma, [9]Katherine Gray, [10]Stephen D Bentley, [11]Neil French, [12]Robert Heyderman, [13]Dean B Everett [Full author list] | BMC Infectious Diseases [curation] | DOI: 10.1186/S12879-015-0980-2
PubMed: 26088623 | Streptococcus pneumoniae [curation] | 2015-06-20 |
| Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis | [1]David T Mzinza, [2]Derek J Sloan, [3]Kondwani C Jambo, [4]Doris Shani, [5]Mercy Kamdolozi, [6]Katalin A Wilkinson, [7]Robert J. Wilkinson, [8]Geraint R. Davies, [9]Robert Heyderman, [10]Henry Mwandumba [Full author list] | Tuberculosis [curation] | DOI: 10.1016/J.TUBE.2015.05.009
PubMed: 26051653 | tuberculosis [curation]; Mycobacterium tuberculosis [curation]; sputum [curation]; pulmonary tuberculosis [curation] | 2015-05-28 |
| Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events | [1]Vanessa N.L. Wong, [2]Stephen Baker, [3]Derek J Pickard, [4]Julian Parkhill, [5]Andrew J. Page, [6]Nicholas A Feasey, [7]Robert A Kingsley, [8]Nicholas Thomson, [9]Jacqueline A Keane, [10]François-Xavier Weill, ..., [23]Samuel Kariuki, [24]Melita A. Gordon, [25]Robert Heyderman, [26]Chinyere K. Okoro, [27]Jan Jacobs, ... [Full author list] | Nature Genetics [curation] | DOI: 10.1038/NG.3281
PubMed: 25961941 | multiple drug resistance [curation]; Salmonella typhi [curation] | 2015-05-11 |
| Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages | [1]Jamie Rylance, [2]Duncan G Fullerton, [3]James Scriven, [4]Abdullah N Aljurayyan, [5]David T Mzinza, [6]Steve D Barrett, [7]Adam K A Wright, [8]Daniel G Wootton, [9]Sarah J Glennie, [10]Katy Baple, [11]Amy Knott, [12]Kevin Mortimer, [13]David G Russell, [14]Robert Heyderman, [15]Siamon Gordon [Full author list] | American Journal of Respiratory Cell and Molecular Biology [curation] | DOI: 10.1165/RCMB.2014-0188OC
PubMed: 25254931 | air pollution [curation]; phagocytosis [curation] | 2015-05-01 |
| Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi | [1]Nicholas A Feasey, [2]Katherine M Gaskell, [3]Vanessa N.L. Wong, [4]Chisomo L Msefula, [5]George Selemani, [6]Save Kumwenda, [7]Theresa J Allain, [8]Jane Mallewa, [9]Neil Kennedy, [10]Aisleen Bennett, [11]Joram O Nyirongo, [12]Patience A Nyondo, [13]Madalitso D Zulu, [14]Julian Parkhill, [15]Gordon Dougan, [16]Melita A. Gordon, [17]Robert Heyderman [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0003748
PubMed: 25909750 | Malawi [curation]; multiple drug resistance [curation]; Salmonella typhi [curation] | 2015-04-24 |
| Methods and challenges in measuring the impact of national pneumococcal and rotavirus vaccine introduction on morbidity and mortality in Malawi | [1]Naor Bar-Zeev, [2]Lester Kapanda Phiri, [3]Carina King, [4]James Beard, [5]Tambosi Phiri, [6]Hazzie Mvula, [7]Amelia Crampin, [8]Charles Mwansambo, [9]Anthony Costello, [10]Umesh Parashar, [11]Jacqueline E Tate, [12]Jennifer R Verani, [13]Cynthia G Whitney, [14]Robert Heyderman, [15]Nigel A. Cunliffe, [16]Neil French, [17]VacSurv Consortium [Full author list] | Vaccine [curation] | DOI: 10.1016/J.VACCINE.2015.04.053
PubMed: 25917672 | Malawi [curation]; rotavirus vaccine [curation] | 2015-04-24 |
| Determination of a Viral Load Threshold To Distinguish Symptomatic versus Asymptomatic Rotavirus Infection in a High-Disease-Burden African Population | [1]Aisleen Bennett, [2]Naor Bar-Zeev, [3]Khuzwayo C. Jere, [4]Jacqueline E Tate, [5]Umesh Parashar, [6]O Nakagomi, [7]Robert Heyderman, [8]N French, [9]Miren Iturriza, [10]Nigel A. Cunliffe [Full author list] | Journal of Clinical Microbiology [curation] | DOI: 10.1128/JCM.00875-15
PubMed: 25854480 | viral load [curation] | 2015-04-08 |
| Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis | [1]Derek J Sloan, [2]Henry Mwandumba, [3]Natalie J Garton, [4]Saye Khoo, [5]Anthony E Butterworth, [6]Theresa J Allain, [7]Robert Heyderman, [8]Elizabeth L. Corbett, [9]Michael R Barer, [10]Geraint R. Davies [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIV195
PubMed: 25778753 | tuberculosis [curation]; sputum [curation]; pharmacodynamics [curation]; pulmonary tuberculosis [curation] | 2015-03-16 |
| Brain swelling and death in children with cerebral malaria | [1]Karl B Seydel, [2]Samuel D Kampondeni, [3]Clarissa Valim, [4]Michael J Potchen, [5]Danny Milner, [6]Francis W Muwalo, [7]Gretchen L Birbeck, [8]William G Bradley, [9]Lindsay L Fox, [10]Simon J Glover, [11]Colleen A Hammond, [12]Robert Heyderman, [13]Cowles A Chilingulo, [14]Malcolm Molyneux, [15]Terrie E Taylor [Full author list] | The New England Journal of Medicine [curation] | DOI: 10.1056/NEJMOA1400116
PubMed: 25785970 | malaria [curation]; cerebral malaria [curation] | 2015-03-01 |
| Barriers to successful early infant diagnosis of HIV infection at primary care level in Malawi | [1]Elizabeth A Cromwell, [2]Anna E Dow, [3]Daniel Low, [4]Chawanangwa Chirambo, [5]Robert Heyderman, [6]Queen Dube, [7]Annelies Van Rie [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000000625
PubMed: 25742076 | Malawi [curation] | 2015-03-01 |
| Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries | [1]Meredith L McMorrow, [2]Emile Okitolonda-Wemakoy, [3]Joelle Kabamba Tshilobo, [4]Gideon O Emukule, [5]Joshua A Mott, [6]Henry N Njuguna, [7]Lilian W Waiboci, [8]Jean-Michel Héraud, [9]Soatianana Rajatonirina, [10]Norosoa H Razanajatovo, [11]Moses Chilombe, [12]Dean B Everett, [13]Robert Heyderman, [14]Amal Z. Barakat, [15]Thierry Nyatanyi, ... [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIV100
PubMed: 25712970 | Sub-Saharan Africa [curation]; acute respiratory disease [curation] | 2015-02-23 |
| Management of severe non-TB bacterial infection in HIV-infected adults | [1]Katherine M Gaskell, [2]Nicholas A Feasey, [3]Robert Heyderman [Full author list] | Expert Review of Anti-infective Therapy [curation] | DOI: 10.1586/14787210.2015.995631
PubMed: 25578883 | | 2015-02-01 |
| Effectiveness of a monovalent rotavirus vaccine in infants in Malawi after programmatic roll-out: an observational and case-control study | [1]Naor Bar-Zeev, [2]Lester Kapanda Phiri, [3]Jacqueline E Tate, [4]Khuzwayo C. Jere, [5]Miren Iturriza-Gómara, [6]Osamu Nakagomi, [7]Charles Mwansambo, [8]Anthony Costello, [9]Umesh Parashar, [10]Robert Heyderman, [11]Neil French, [12]Nigel A. Cunliffe, [13]VacSurv Consortium [Full author list] | Lancet Infectious Diseases [curation] | DOI: 10.1016/S1473-3099(14)71060-6
PubMed: 25638521 | Malawi [curation]; vaccine [curation]; rotavirus vaccine [curation] | 2015-01-29 |
| T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence | [1]Tonney S Nyirenda, [2]Malcolm Molyneux, [3]Rupert Kenefeck, [4]Lucy S K Walker, [5]Calman A MacLennan, [6]Robert Heyderman, [7]Wilson L Mandala [Full author list] | Journal of the Pediatric Infectious Diseases Society [curation] | DOI: 10.1093/JPIDS/PIU140
PubMed: 26335932 | inflammation [curation]; malaria transmission [curation] | 2015-01-07 |
| 845Prediction of Outcome from Adult Bacterial Meningitis in a High HIV Seroprevelence, Resource-Poor Setting Using a New Severity Scoring Tool, the Malawi Adult Meningitis Score (MAMS) | [1]Emma Wall, [2]Mavuto Mukaka, [3]Matthew Scarborough, [4]Katherine M.B. Ajdukiewicz, [5]Katharine Cartwright, [6]Brian Faragher, [7]David Lalloo, [8]Robert Heyderman [Full author list] | Open Forum Infectious Diseases [curation] | DOI: 10.1093/OFID/OFU052.553
| Malawi [curation]; meningitis [curation]; bacterial meningitis [curation] | 2014-12-01 |
| 837Early Goal Directed Therapy for Acute Bacterial Meningitis in Malawian Adults | [1]Emma Wall, [2]Khumbo Kasambala, [3]Veronica Mlozowa, [4]Malango Msukwa, [5]Mavuto Mukaka, [6]Theresa Allain, [7]Mulinda Nyirenda, [8]Brian Faragher, [9]Robert Heyderman, [10]David Lalloo [Full author list] | Open Forum Infectious Diseases [curation] | DOI: 10.1093/OFID/OFU052.545
| meningitis [curation]; bacterial meningitis [curation] | 2014-12-01 |
| CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial | [1]Jeremy Day, [2]Darma Imran, [3]Ahmed Rizal Ganiem, [4]Natriana Tjahjani, [5]Retno Wahyuningsih, [6]Robiatul Adawiyah, [7]David Dance, [8]Mayfong Mayxay, [9]Paul N. Newton, [10]Rattanaphone Phetsouvanh, [11]Sayaphet Rattanavong, [12]Adrienne K Chan, [13]Robert Heyderman, [14]Joep J van Oosterhout, [15]Wirongrong Chierakul, ... [Full author list] | Trials [curation] | DOI: 10.1186/1745-6215-15-441
PubMed: 25391338 | meningitis [curation]; placebo [curation]; dexamethasone [curation]; cryptococcal meningitis [curation]; phase III clinical trial [curation]; study protocol [curation] | 2014-11-12 |
| A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi | [1]Katherine M Gaskell, [2]Camilla Rothe, [3]Roshina Gnanadurai, [4]Patrick Goodson, [5]Chikondi Jassi, [6]Robert Heyderman, [7]Theresa J Allain, [8]Thomas Harrison, [9]David Lalloo, [10]Derek J Sloan, [11]Nicholas A Feasey [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0110285
PubMed: 25375145 | Malawi [curation]; meningitis [curation]; fluconazole [curation]; cryptococcal meningitis [curation] | 2014-11-06 |
| Delayed reconstitution of B cell immunity to pneumococcus in HIV-infected Malawian children on antiretroviral therapy | [1]Oluwadamilola H Iwajomo, [2]Peter Moons, [3]Rose Nkhata, [4]David T Mzinza, [5]Abiodun D Ogunniyi, [6]Neil A Williams, [7]Robert Heyderman, [8]Adam Finn [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2014.10.011
PubMed: 25452037 | | 2014-11-01 |
| Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi | [1]Nicholas A Feasey, [2]Amy K Cain, [3]Chisomo L Msefula, [4]Derek Pickard, [5]Maaike Alaerts, [6]Martin Aslett, [7]Dean B Everett, [8]Theresa J Allain, [9]Gordon Dougan, [10]Melita A. Gordon, [11]Robert Heyderman, [12]Robert A Kingsley [Full author list] | Emerging Infectious Diseases [curation] | DOI: 10.3201/EID2011.141175
PubMed: 25340988 | Malawi [curation]; Salmonella enterica [curation] | 2014-11-01 |
| Invasive Salmonella infections in Africa | [1]John Crump, [2]Robert Heyderman [Full author list] | Transactions of the Royal Society of Tropical Medicine and Hygiene [curation] | DOI: 10.1093/TRSTMH/TRU152
PubMed: 25301531 | | 2014-11-01 |
| Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi | [1]Dalitso Segula, [2]Anne P Frosch, [3]Miguel SanJoaquin, [4]Dalitso Taulo, [5]Jacek Skarbinski, [6]Don P Mathanga, [7]Theresa J Allain, [8]Malcolm Molyneux, [9]Miriam K. Laufer, [10]Robert Heyderman [Full author list] | Malaria Journal [curation] | DOI: 10.1186/1475-2875-13-391
PubMed: 25277278 | Malawi [curation]; malaria [curation]; hospitalization [curation] | 2014-10-02 |
| Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria | [1]Kondwani C Jambo, [2]Dominic H Banda, [3]Louise Afran, [4]Anstead M Kankwatira, [5]Rose D Malamba, [6]Theresa J Allain, [7]Siamon Gordon, [8]Robert Heyderman, [9]David G Russell, [10]Henry Mwandumba [Full author list] | American Journal of Respiratory and Critical Care Medicine [curation] | DOI: 10.1164/RCCM.201405-0864OC
PubMed: 25225948 | anti-retroviral agent [curation] | 2014-10-01 |
| CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations | [1]Daniel Carr, [2]Mas Chaponda, [3]Elena M Cornejo Castro, [4]Andrea L Jorgensen, [5]Saye Khoo, [6]Joep J van Oosterhout, [7]Collet Dandara, [8]Elizabeth Kampira, [9]Francis Ssali, [10]Paula Munderi, [11]David Lalloo, [12]Robert Heyderman, [13]Munir Pirmohamed [Full author list] | Journal of Antimicrobial Chemotherapy [curation] | DOI: 10.1093/JAC/DKU315
PubMed: 25147095 | Uganda [curation]; nevirapine [curation] | 2014-08-20 |
| Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: a longitudinal cohort study | [1]Peter I Waitt, [2]Mavuto Mukaka, [3]Patrick Goodson, [4]Felanji D SimuKonda, [5]Catriona John Waitt, [6]Nick Feasey, [7]Theresa J Allain, [8]Paul Downie, [9]Robert Heyderman [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2014.07.004
PubMed: 25043393 | Malawi [curation]; sepsis [curation]; hospitalization [curation] | 2014-07-17 |
| Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults | [1]Enoch Sepako, [2]Sarah J Glennie, [3]Kondwani C Jambo, [4]David T Mzinza, [5]Oluwadamilola H Iwajomo, [6]Dominic Banda, [7]Joep J van Oosterhout, [8]Neil A Williams, [9]Siamon Gordon, [10]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0100640
PubMed: 24959834 | anti-retroviral agent [curation] | 2014-06-24 |
| Bacterial meningitis in Malawian infants <2 months of age: etiology and susceptibility to World Health Organization first-line antibiotics | [1]Olivia Swann, [2]Dean B Everett, [3]Jeremy Furyk, [4]Ewen M Harrison, [5]Malango T Msukwa, [6]Robert Heyderman, [7]Elizabeth M Molyneux [Full author list] | Pediatric Infectious Disease Journal [curation] | DOI: 10.1097/INF.0000000000000210
PubMed: 24378940 | World Health Organization [curation]; antibiotic [curation]; meningitis [curation]; bacterial meningitis [curation] | 2014-06-01 |
| Diagnosis of childhood tuberculosis and host RNA expression in Africa | [1]Suzanne T Anderson, [2]Myrsini Kaforou, [3]Andrew J Brent, [4]Victoria J Wright, [5]Claire M Banwell, [6]George Chagaluka, [7]Amelia Crampin, [8]Hazel Dockrell, [9]Neil French, [10]Melissa S Hamilton, ..., [21]Robert J. Wilkinson, [22]Lachlan Coin, [23]Robert Heyderman, [24]Michael Levin, [25]Brian Eley [Full author list] | The New England Journal of Medicine [curation] | DOI: 10.1056/NEJMOA1303657
PubMed: 24785206 | tuberculosis [curation] | 2014-05-01 |
| HIV-exposed uninfected children: a growing population with a vulnerable immune system? | [1]L Afran, [2]Miguel A Garcia-Knight, [3]E Nduati, [4]Britta C Urban, [5]Robert Heyderman, [6]S L Rowland-Jones [Full author list] | Clinical and Experimental Immunology [curation] | DOI: 10.1111/CEI.12251
PubMed: 24325737 | maternal health [curation] | 2014-04-01 |
| A reduction in adult blood stream infection and case fatality at a large African hospital following antiretroviral therapy roll-out | [1]Nicholas A Feasey, [2]Angela Houston, [3]Mavuto Mukaka, [4]Dan Komrower, [5]Thandie Mwalukomo, [6]Lyson Tenthani, [7]Andreas Jahn, [8]Mike Moore, [9]Remco P H Peters, [10]Melita A. Gordon, [11]Dean B Everett, [12]Neil French, [13]Joep J van Oosterhout, [14]Theresa J Allain, [15]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0092226
PubMed: 24643091 | anti-retroviral agent [curation] | 2014-03-18 |
| Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012. | [1]Emma C Wall, [2]Dean B Everett, [3]Mavuto Mukaka, [4]Naor Bar-Zeev, [5]Nicholas A Feasey, [6]Andreas Jahn, [7]Mike Moore, [8]Joep J van Oosterhout, [9]Paul Pensalo, [10]Kenneth Baguimira, [11]Siamon Gordon, [12]Elizabeth M Molyneux, [13]Enitan D Carrol, [14]Neil French, [15]Malcolm Molyneux, [16]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIU057
PubMed: 24496208 | meningitis [curation]; Haemophilus influenzae [curation]; teenager [curation]; bacterial meningitis [curation]; anti-retroviral agent [curation] | 2014-02-04 |
| Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function | [1]Kondwani C Jambo, [2]D H Banda, [3]A M Kankwatira, [4]N Sukumar, [5]T J Allain, [6]Robert Heyderman, [7]David G Russell, [8]H C Mwandumba [Full author list] | Mucosal Immunology [curation] | DOI: 10.1038/MI.2013.127
PubMed: 24472847 | | 2014-01-29 |
| Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children | [1]Tonney S Nyirenda, [2]James J Gilchrist, [3]Nicholas A Feasey, [4]Sarah J Glennie, [5]Naor Bar-Zeev, [6]Melita A. Gordon, [7]Calman A MacLennan, [8]Wilson L Mandala, [9]Robert Heyderman [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIU045
PubMed: 24443544 | | 2014-01-16 |
| Validity of US norms for the Bayley Scales of Infant Development-III in Malawian children | [1]Elizabeth A Cromwell, [2]Queen Dube, [3]Stephen R Cole, [4]Chawanangwa Chirambo, [5]Anna E Dow, [6]Robert Heyderman, [7]Annelies Van Rie [Full author list] | European Journal of Paediatric Neurology [curation] | DOI: 10.1016/J.EJPN.2013.11.011
PubMed: 24423629 | | 2013-12-31 |
| Human tonsil-derived dendritic cells are poor inducers of T cell immunity to mucosally encountered pathogens | [1]Claire M Hallissey, [2]Robert Heyderman, [3]Neil A Williams [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIT819
PubMed: 24371254 | dendritic cell [curation] | 2013-12-26 |
| Polysaccharide-specific memory B cells generated by conjugate vaccines in humans conform to the CD27+IgG+ isotype-switched memory B Cell phenotype and require contact-dependent signals from bystander T cells activated by bacterial proteins to differ | [1]Edward T Clarke, [2]Neil A Williams, [3]Jamie Findlow, [4]Ray Borrow, [5]Robert Heyderman, [6]Adam Finn [Full author list] | Journal of Immunology [curation] | DOI: 10.4049/JIMMUNOL.1203254
PubMed: 24227777 | polysaccharide [curation]; memory B cell [curation] | 2013-11-13 |
| Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi. | [1]Laura Dickinson, [2]Masautso Chaponda, [3]Daniel Carr, [4]Joep J van Oosterhout, [5]Johnstone Kumwenda, [6]David Lalloo, [7]Munir Pirmohamed, [8]Robert Heyderman, [9]Saye H Khoo [Full author list] | Antimicrobial Agents and Chemotherapy [curation] | DOI: 10.1128/AAC.02069-13
PubMed: 24217698 | Malawi [curation]; HIV [curation]; nevirapine [curation]; pharmacokinetics [curation] | 2013-11-11 |
| Impairment of pneumococcal antigen specific isotype-switched Igg memory B-cell immunity in HIV infected Malawian adults | [1]Oluwadamilola H Iwajomo, [2]Adam Finn, [3]Abiodun D Ogunniyi, [4]Neil A Williams, [5]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0078592
PubMed: 24223825 | | 2013-11-04 |
| Severe toxicity and polymerase-γ gene abnormalities in Malawian adults on stavudine-based antiretroviral therapy | [1]Joep J van Oosterhout, [2]Kristian Gardner, [3]Jane Mallewa, [4]Symon Kaunda, [5]Elizabeth Kampira, [6]Brendan Payne, [7]Robert Heyderman, [8]Patrick F. Chinnery [Full author list] | Pharmacogenetics and Genomics [curation] | DOI: 10.1097/FPC.0B013E3283655053
PubMed: 23962909 | stavudine [curation] | 2013-11-01 |
| Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study | [1]Myrsini Kaforou, [2]Victoria J Wright, [3]Tolu Oni, [4]Neil French, [5]Suzanne T Anderson, [6]Nonzwakazi Bangani, [7]Claire M Banwell, [8]Andrew J Brent, [9]Amelia Crampin, [10]Hazel Dockrell, [11]Brian Eley, [12]Robert Heyderman, [13]Martin L. Hibberd, [14]Florian Kern, ... [Full author list] | PLOS MEDICINE [curation] | DOI: 10.1371/JOURNAL.PMED.1001538
PubMed: 24167453 | tuberculosis [curation]; whole blood [curation] | 2013-10-01 |
| Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi | [1]Jen Cornick, [2]Simon R Harris, [3]Christopher M Parry, [4]Michael J Moore, [5]Chikondi Jassi, [6]Arox W Kamng'ona, [7]Benard Kulohoma, [8]Robert Heyderman, [9]Stephen D Bentley, [10]Dean B Everett [Full author list] | Journal of Antimicrobial Chemotherapy [curation] | DOI: 10.1093/JAC/DKT384
PubMed: 24080503 | Malawi [curation]; Streptococcus pneumoniae [curation]; sulfamethoxazole/trimethoprim [curation] | 2013-09-29 |
| Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children | [1]Christopher A Moxon, [2]Ngawina V Chisala, [3]Samuel C Wassmer, [4]Terrie E Taylor, [5]Karl B Seydel, [6]Malcolm Molyneux, [7]Brian Faragher, [8]Neil Kennedy, [9]Cheng-Hock Toh, [10]Alister G Craig, [11]Robert Heyderman [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIT419
PubMed: 24048963 | inflammation [curation]; endothelium [curation]; Plasmodium falciparum [curation] | 2013-09-17 |
| Piliation of invasive Streptococcus pneumoniae isolates in the era before pneumococcal conjugate vaccine introduction in Malawi | [1]Benard Kulohoma, [2]Katherine Gray, [3]Arox W Kamng'ona, [4]Jen Cornick, [5]Stephen D Bentley, [6]Robert Heyderman, [7]Dean B Everett [Full author list] | Clinical and Vaccine Immunology [curation] | DOI: 10.1128/CVI.00403-13
PubMed: 24027261 | Malawi [curation]; Streptococcus pneumoniae [curation]; pneumococcal conjugate vaccine [curation] | 2013-09-11 |
| Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities | [1]Newton Chagoma, [2]Jane Mallewa, [3]Symon Kaunda, [4]Yasin Njalale, [5]Elizabeth Kampira, [6]Mavuto Mukaka, [7]Robert Heyderman, [8]Joep J van Oosterhout [Full author list] | Transactions of the Royal Society of Tropical Medicine and Hygiene [curation] | DOI: 10.1093/TRSTMH/TRT074
PubMed: 23926161 | stavudine [curation] | 2013-08-07 |
| High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi | [1]Emma C Wall, [2]Katharine Cartwright, [3]Matthew Scarborough, [4]Katherine M Ajdukiewicz, [5]Patrick Goodson, [6]James Mwambene, [7]Eduard E Zijlstra, [8]Siamon Gordon, [9]Neil French, [10]Brian Faragher, [11]Robert Heyderman, [12]David Lalloo [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0069783
PubMed: 23894538 | Malawi [curation]; meningitis [curation]; Sub-Saharan Africa [curation]; teenager [curation]; bacterial meningitis [curation] | 2013-07-19 |
| Recognising and treatment seeking for acute bacterial meningitis in adults and children in resource-poor settings: a qualitative study | [1]Nicola Desmond, [2]Deborah Nyirenda, [3]Queen Dube, [4]MacPherson Mallewa, [5]Elizabeth Molyneux, [6]David Lalloo, [7]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0068163
PubMed: 23861864 | meningitis [curation]; bacterial meningitis [curation] | 2013-07-04 |
| Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children | [1]Christopher A Moxon, [2]Samuel C Wassmer, [3]Danny Milner, [4]Ngawina V Chisala, [5]Terrie E Taylor, [6]Karl B Seydel, [7]Malcolm Molyneux, [8]Brian Faragher, [9]Charles T Esmon, [10]Colin Downey, [11]Cheng-Hock Toh, [12]Alister G Craig, [13]Robert Heyderman [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2013-03-490219
PubMed: 23741007 | malaria [curation]; inflammation [curation]; endothelium [curation]; cerebral malaria [curation] | 2013-06-05 |
| Human melioidosis, Malawi, 2011. | [1]Thembi Katangwe, [2]Janet Purcell, [3]Naor Bar-Zeev, [4]Brigitte Denis, [5]Jacqui Montgomery, [6]Maaike Alaerts, [7]Robert Heyderman, [8]David Dance, [9]Neil Kennedy, [10]Nicholas A Feasey, [11]Christopher Alan Moxon [Full author list] | Emerging Infectious Diseases [curation] | DOI: 10.3201/EID1906.120717
PubMed: 23735189 | Malawi [curation]; melioidosis [curation] | 2013-06-01 |
| Evaluation of Xpert MTB/RIF for detection of tuberculosis from blood samples of HIV-infected adults confirms Mycobacterium tuberculosis bacteremia as an indicator of poor prognosis | [1]Nicholas A Feasey, [2]Padmapriya P. Banada, [3]William Howson, [4]Derek J Sloan, [5]Aaron Mdolo, [6]Catharina Boehme, [7]Geoffrey A Chipungu, [8]Theresa J Allain, [9]Robert Heyderman, [10]Elizabeth L. Corbett, [11]David Alland [Full author list] | Journal of Clinical Microbiology [curation] | DOI: 10.1128/JCM.00330-13
PubMed: 23678061 | tuberculosis [curation]; Mycobacterium tuberculosis [curation] | 2013-05-15 |
| When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children | [1]Jim Todd, [2]Robert Heyderman, [3]Philippa Musoke, [4]Tim Peto [Full author list] | Trials [curation] | DOI: 10.1186/1745-6215-14-85
PubMed: 23531379 | | 2013-03-26 |
| Surveillance Programme of IN-patients and Epidemiology (SPINE): implementation of an electronic data collection tool within a large hospital in Malawi | [1]Miguel A SanJoaquin, [2]Theresa J Allain, [3]Malcolm Molyneux, [4]Laura A Benjamin, [5]Dean B Everett, [6]Oliver Gadabu, [7]Camilla Rothe, [8]Patrick Nguipdop, [9]Moses Chilombe, [10]Lawrence Kazembe, [11]Servace Sakala, [12]Andrew Gonani, [13]Robert Heyderman [Full author list] | PLOS MEDICINE [curation] | DOI: 10.1371/JOURNAL.PMED.1001400
PubMed: 23554578 | Malawi [curation]; epidemiology [curation]; data collection [curation] | 2013-03-12 |
| Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population | [1]Daniel Carr, [2]Mas Chaponda, [3]Andrea L Jorgensen, [4]Elena Cornejo Castro, [5]Joep J van Oosterhout, [6]Saye H Khoo, [7]David Lalloo, [8]Robert Heyderman, [9]Ana Alfirevic, [10]Munir Pirmohamed [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIT021
PubMed: 23362284 | nevirapine [curation] | 2013-01-29 |
| Osmotic therapies added to antibiotics for acute bacterial meningitis | [1]Emma C B Wall, [2]Katherine M B Ajdukiewicz, [3]Robert Heyderman, [4]Paul Garner [Full author list] | Cochrane Database of Systematic Reviews [curation] | DOI: 10.1002/14651858.CD008806.PUB2
PubMed: 23543568 | antibiotic [curation]; meningitis [curation]; bacterial meningitis [curation] | 2013-01-01 |
| A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi | [1]Camilla Rothe, [2]Derek J Sloan, [3]Patrick Goodson, [4]Jean Chikafa, [5]Mavuto Mukaka, [6]Brigitte Denis, [7]Tom Harrison, [8]Joep J van Oosterhout, [9]Robert Heyderman, [10]David Lalloo, [11]Theresa Allain, [12]Nicholas A Feasey [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0067311
PubMed: 23840659 | Malawi [curation]; meningitis [curation]; fluconazole [curation]; cryptococcal meningitis [curation] | 2013-01-01 |
| Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children | [1]Christa Buckheit Sturdevant, [1-Q47412534]Christa Buckheit Sturdevant, [2]Anna Dow, [3]Cassandra B Jabara, [4]Sarah B Joseph, [5]Gretja Schnell, [5-Q47412515]Gretja Schnell, [6]Nobutoki Takamune, [7]Macpherson Mallewa, [8]Robert Heyderman, [9]Annelies Van Rie, [10]Ronald Swanstrom [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1003094
PubMed: 23300446 | | 2012-12-27 |
| Regulation of naturally acquired mucosal immunity to Streptococcus pneumoniae in healthy Malawian adults and children | [1]Sarah J Glennie, [2]Dominic Banda, [3]Wakisa Mulwafu, [4]Rose Nkhata, [5]Neil A Williams, [6]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0051425
PubMed: 23284694 | Streptococcus pneumoniae [curation] | 2012-12-17 |
| Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi | [1]Monique van Lettow, [2]Ann Åkesson, [3]Alexandra Martiniuk, [4]Andrew Ramsay, [5]Adrienne K Chan, [6]Suzanne T Anderson, [7]Anthony D Harries, [8]Elizabeth L. Corbett, [9]Robert Heyderman, [10]Rony Zachariah, [11]Richard Bedell [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0048856
PubMed: 23185278 | Malawi [curation]; diarrhea [curation]; anti-retroviral agent [curation] | 2012-11-19 |
| Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa | [1]Chinyere K. Okoro, [2]Robert A Kingsley, [3]Thomas R. Connor, [4]Simon R Harris, [5]Christopher M Parry, [6]Manar N Al-Mashhadani, [7]Samuel Kariuki, [8]Chisomo L Msefula, [9]Melita A. Gordon, [10]Elizabeth De Pinna, [11]John Wain, [12]Robert Heyderman, [13]Stephen Obaro, [14]Pedro L. Alonso, ... [Full author list] | Nature Genetics [curation] | DOI: 10.1038/NG.2423
PubMed: 23023330 | Sub-Saharan Africa [curation]; Salmonella Typhimurium [curation] | 2012-09-30 |
| Defective pneumococcal-specific Th1 responses in HIV-infected adults precedes a loss of control of pneumococcal colonization | [1]Sarah J Glennie, [2]Dominic Banda, [3]Kate Gould, [4]Jason Hinds, [5]Arox Kamngona, [6]Dean D B Everett, [7]Neil A Williams, [8]Robert Heyderman [Full author list] | Clinical Infectious Diseases [curation] | DOI: 10.1093/CID/CIS842
PubMed: 23024291 | | 2012-09-28 |
| Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach | [1]Dean B Everett, [2]Jen Cornick, [3]Brigitte Denis, [4]Claire Chewapreecha, [5]Nicholas J Croucher, [6]Simon R Harris, [7]Julian Parkhill, [8]Siamon Gordon, [9]Enitan D Carrol, [10]Neil French, [11]Robert Heyderman, [12]Stephen D Bentley [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0044250
PubMed: 22970189 | whole genome sequencing [curation] | 2012-09-10 |
| Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi | [1]Chisomo L Msefula, [2]Robert A Kingsley, [3]Melita A. Gordon, [4]Elizabeth Molyneux, [5]Malcolm Molyneux, [6]Calman A MacLennan, [7]Gordon Dougan, [8]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0042085
PubMed: 22848711 | Malawi [curation]; multiple drug resistance [curation] | 2012-07-27 |
| Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi | [1]Joep J van Oosterhout, [2]Jane Mallewa, [3]Symon Kaunda, [4]Newton Chagoma, [5]Yassin Njalale, [6]Elizabeth Kampira, [7]Mavuto Mukaka, [8]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0042029
PubMed: 22848696 | Malawi [curation]; stavudine [curation] | 2012-07-26 |
| Detection of herpes viruses in the cerebrospinal fluid of adults with suspected viral meningitis in Malawi | [1]Laura A Benjamin, [2]M Kelly, [3]D Cohen, [4]F Neuhann, [5]Sareen Elizabeth Galbraith, [6]M Mallewa, [7]M Hopkins, [8]I J Hart, [9]M Guiver, [10]David Lalloo, [11]Robert Heyderman, [12]Tom Solomon [Full author list] | Infection [curation] | DOI: 10.1007/S15010-012-0292-Z
PubMed: 22798048 | Malawi [curation]; meningitis [curation]; cerebrospinal fluid [curation]; viral meningitis [curation] | 2012-07-14 |
| Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa | [1]Nicholas A Feasey, [2]Gordon Dougan, [3]Robert A Kingsley, [4]Robert Heyderman, [5]Melita A. Gordon [Full author list] | The Lancet [curation] | DOI: 10.1016/S0140-6736(11)61752-2
PubMed: 22587967 | salmonellosis [curation]; neglected tropical disease [curation]; human immunodeficiency virus infectious disease [curation]; Retroviridae infectious disease [curation] | 2012-06-30 |
| Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults | [1]Kondwani C Jambo, [2]Enoch Sepako, [3]Sarah J Glennie, [4]David T Mzinza, [5]Neil A Williams, [6]Siamon Gordon, [7]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0038628
PubMed: 22715399 | | 2012-06-08 |
| Lack of decline in childhood malaria, Malawi, 2001-2010 | [1]Arantxa Roca-Feltrer, [2]Collins J Kwizombe, [3]Miguel A Sanjoaquin, [4]Sanie Sesay, [5]Brian Faragher, [6]James Harrison, [7]Karen Geukers, [8]Storn Kabuluzi, [9]Don P Mathanga, [10]Elizabeth Molyneux, [11]Maganizo Chagomera, [12]Terrie Taylor, [13]Malcolm Molyneux, [14]Robert Heyderman [Full author list] | Emerging Infectious Diseases [curation] | DOI: 10.3201/EID1802.111008
PubMed: 22305090 | Malawi [curation]; malaria [curation] | 2012-02-01 |
| Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue | [1]Jeffrey Pido-Lopez, [2]William W Kwok, [3]Timothy J Mitchell, [4]Robert Heyderman, [5]Neil A Williams [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1002396
PubMed: 22144893 | | 2011-12-01 |
| Epstein-barr virus coinfection in cerebrospinal fluid is associated with increased mortality in Malawian adults with bacterial meningitis | [1]Matthew J Kelly, [2]Laura A Benjamin, [3]Katharine Cartwright, [4]Katherine M B Ajdukiewicz, [5]Danielle B Cohen, [6]Mavis Menyere, [7]Sareen Elizabeth Galbraith, [8]Malcolm Guiver, [9]Florian Neuhann, [10]Tom Solomon, [11]David Lalloo, [12]Robert Heyderman [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIR707
PubMed: 22075766 | Epstein–Barr virus [curation]; meningitis [curation]; cerebrospinal fluid [curation] | 2011-11-09 |
| Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults | [1]Sarah J Glennie, [2]Enoch Sepako, [3]David T Mzinza, [4]Visopo Harawa, [5]David J C Miles, [6]Kondwani C Jambo, [7]Siamon Gordon, [8]Neil A Williams, [9]Robert Heyderman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0025610
PubMed: 21980502 | Streptococcus pneumoniae [curation] | 2011-09-27 |
| The challenges of managing severe dehydrating diarrhoea in a resource-limited setting | [1]Lloyd L Bwanaisa, [2]Robert Heyderman, [3]Elizabeth M Molyneux [Full author list] | International Health [curation] | DOI: 10.1016/J.INHE.2011.03.007
PubMed: 24038363 | diarrhea [curation] | 2011-09-01 |
| Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults | [1]Kondwani C Jambo, [2]Enoch Sepako, [3]Duncan G Fullerton, [4]David T Mzinza, [5]Sarah Glennie, [6]Adam K Wright, [7]Robert Heyderman, [8]Siamon Gordon [Full author list] | Thorax [curation] | DOI: 10.1136/THX.2010.153825
PubMed: 21357587 | | 2011-02-25 |
| Mucosal immunity in resource-limited setting: is the battle ground different? | [1]Sarah J Glennie, [2]Neil A Williams, [3]Robert Heyderman [Full author list] | Trends in Microbiology [curation] | DOI: 10.1016/J.TIM.2010.08.002
PubMed: 20832319 | | 2010-09-09 |
| Typhoid fever and invasive nontyphoid salmonellosis, Malawi and South Africa | [1]Nicholas A Feasey, [2]Brett N Archer, [3]Robert Heyderman, [4]Arvinda Sooka, [5]Brigitte Dennis, [6]Melita A. Gordon, [7]Karen H Keddy [Full author list] | Emerging Infectious Diseases [curation] | DOI: 10.3201/EID1609.100125
PubMed: 20735930 | South Africa [curation]; Malawi [curation]; typhoid fever [curation] | 2010-09-01 |
| Neisseria lactamica selectively induces mitogenic proliferation of the naive B cell pool via cell surface Ig | [1]Andrew T Vaughan, [2]Louise S Brackenbury, [3]Paola Massari, [4]Victoria Davenport, [5]Andrew Gorringe, [6]Robert Heyderman, [7]Neil A Williams [Full author list] | Journal of Immunology [curation] | DOI: 10.4049/JIMMUNOL.0902468
PubMed: 20709949 | Neisseria lactamica [curation] | 2010-08-13 |
| Potential role for mucosally active vaccines against pneumococcal pneumonia | [1]Kondwani C Jambo, [2]Enoch Sepako, [3]Robert Heyderman, [4]Siamon Gordon [Full author list] | Trends in Microbiology [curation] | DOI: 10.1016/J.TIM.2009.12.001
PubMed: 20031415 | mucosal immune system [curation]; pneumococcal pneumonia [curation]; pneumococcal vaccine [curation] | 2010-02-01 |
| Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi | [1]L Dickinson, [2]M Chaponda, [3]D Carr, [4]JJ van Oosterhout, [5]J Kumwenda, [6]DG Lalloo, [7]Munir Pirmohamed, [8]Robert Heyderman, [9]SH Khoo [Full author list] | Journal of the International AIDS Society [curation] | DOI: 10.1186/1758-2652-13-S4-P181
| Malawi [curation]; nevirapine [curation]; pharmacokinetics [curation] | 2010-01-01 |
| Dysregulation of coagulation in cerebral malaria | [1]Christopher Alan Moxon, [2]Robert Heyderman, [3]Samuel Crocodile Wassmer [Full author list] | Molecular and Biochemical Parasitology [curation] | DOI: 10.1016/J.MOLBIOPARA.2009.03.006
PubMed: 19450727 | malaria [curation]; eukaryote [curation]; blood coagulation [curation]; Plasmodium falciparum [curation]; blood proteins [curation]; cerebral malaria [curation]; blood coagulation factors [curation] | 2009-08-01 |
| The macrophage marches on its phagosome: dynamic assays of phagosome function | [1]David G Russell, [2]Brian C Vanderven, [3]Sarah Glennie, [4]Henry Mwandumba, [5]Robert Heyderman [Full author list] | Nature Reviews Immunology [curation] | DOI: 10.1038/NRI2591
PubMed: 19590530 | macrophage [curation] | 2009-07-10 |
| Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency | [1]Begonia Morales-Aza, [2]Sarah J Glennie, [3]Tomaz Garcez, [4]Victoria Davenport, [5]Sarah L Johnston, [6]Neil A Williams, [7]Robert Heyderman [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2008-08-171587
PubMed: 19202131 | | 2009-02-06 |
| Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage | [1]Andrew T Vaughan, [2]Andrew Gorringe, [3]Victoria Davenport, [4]Neil A Williams, [5]Robert Heyderman [Full author list] | Journal of Immunology [curation] | DOI: 10.4049/JIMMUNOL.0802531
PubMed: 19201877 | Neisseria meningitidis [curation]; Neisseria lactamica [curation] | 2009-02-01 |
| British HIV Association guidelines for immunization of HIV-infected adults 2008 | [1]A M Geretti, [2]BHIVA Immunization Writing Committee, [3]Gary Brook, [4]Claire Cameron, [5]David Chadwick, [6]Robert Heyderman, [7]Eithne MacMahon, [8]Anton Pozniak, [9]Mary Ramsay, [10]M Schuhwerk [Full author list] | HIV Medicine [curation] | DOI: 10.1111/J.1468-1293.2008.00637.X
PubMed: 18983477 | | 2008-11-01 |
| Mucosal immunity in healthy adults after parenteral vaccination with outer-membrane vesicles from Neisseria meningitidis serogroup B | [1]Victoria Davenport, [2]Eleanor Groves, [3]Rachel E Horton, [4]Christopher G Hobbs, [5]Terry Guthrie, [6]Jamie Findlow, [7]Ray Borrow, [8]Lisbeth M Naess, [9]Philipp Oster, [10]Robert Heyderman, [11]Neil A Williams [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1086/590669
PubMed: 18636953 | Neisseria meningitidis [curation] | 2008-09-01 |
| IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1 | [1]Natalie J Griffiths, [2]Christopher J Bradley, [3]Robert Heyderman, [4]Mumtaz Virji [Full author list] | Cellular Microbiology [curation] | DOI: 10.1111/J.1462-5822.2007.01038.X
PubMed: 17764466 | Neisseria meningitidis [curation]; cell adhesion [curation] | 2007-08-30 |
| Comparison and Correlation of Serogroup B Immunologic Assay Results and Human Antibody Responses following Three Doses of the Norwegian Meningococcal Outer Membrane Vesicle Vaccine MenBvac | [1]Jamie Findlow, [2]Stephen Taylor, [3]Audun Aase, [4]Rachel Horton, [5]Robert Heyderman, [6]Jo Southern, [7]Nick Andrews, [8]Rita Barchha, [9]Ewan Harrison, [10]Ann Lowe, [11]Emma Boxer, [12]Charlotte Heaton, [13]Paul Balmer, [14]Ed Kaczmarski, [15]Philipp Oster, [16]Andrew Gorringe, [17]Ray Borrow, [18]Elizabeth Miller [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.00768-07
| | 2007-08-01 |
| Quality of in-hospital care for adults with acute bacterial meningitis: a national retrospective survey | [1]Gjini AB, [2]Stuart JM, [3]Cartwright K, [4]Cohen J, [5]Jacobs M, [6]Nichols T, [7]Ninis N, [8]Prempeh H, [9]Whitehouse A, [10]Robert Heyderman [Full author list] | QJM: An International Journal of Medicine [curation] | DOI: 10.1093/QJMED/HCL111
PubMed: 17071621 | meningitis [curation]; bacterial meningitis [curation] | 2006-11-01 |
| Comparison and correlation of neisseria meningitidis serogroup B immunologic assay results and human antibody responses following three doses of the Norwegian meningococcal outer membrane vesicle vaccine MenBvac | [1]Jamie Findlow, [2]Stephen Taylor, [3]Audun Aase, [4]Rachel Horton, [5]Robert Heyderman, [6]Jo Southern, [7]Nick Andrews, [8]Rita Barchha, [9]Ewan M. Harrison, [10]Ann Lowe, [11]Emma Boxer, [12]Charlotte Heaton, [13]Paul Balmer, [14]Ed Kaczmarski, [15]Philipp Oster, [16]Andrew Gorringe, [17]Ray Borrow, [18]Elizabeth Miller [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.00466-06
PubMed: 16861642 | antibody [curation]; Neisseria meningitidis [curation] | 2006-08-01 |
| Human papillomavirus and head and neck cancer: a systematic review and meta-analysis | [1]Hobbs CG, [2]Jonathan Sterne, [3]Bailey M, [4]Robert Heyderman, [5]Birchall MA, [6]Thomas SJ [Full author list] | Clinical Otolaryngology [curation] | DOI: 10.1111/J.1749-4486.2006.01246.X
PubMed: 16911640 | meta-analysis [curation]; systematic review [curation]; head and neck cancer [curation]; head and neck carcinoma [curation]; neck cancer [curation] | 2006-08-01 |
| Current concepts in the treatment of bacterial meningitis beyond the neonatal period | [1]Edward T Clarke, [2]Robert Heyderman [Full author list] | Expert Review of Anti-infective Therapy [curation] | DOI: 10.1586/14787210.4.4.663
PubMed: 17009944 | meningitis [curation]; bacterial meningitis [curation] | 2006-08-01 |
| Platelet and soluble CD40L in meningococcal sepsis | [1]David P Inwald, [2]Saul N Faust, [3]Paula Lister, [4]Mark J Peters, [5]Michael Levin, [6]Robert Heyderman, [7]Nigel Klein [Full author list] | Intensive Care Medicine [curation] | DOI: 10.1007/S00134-006-0250-2
PubMed: 16810523 | sepsis [curation] | 2006-06-30 |
| Changing epidemiology of bacterial meningitis among adults in England and Wales 1991-2002 | [1]Gjini AB, [2]Stuart JM, [3]Deborah A. Lawlor, [4]Cartwright KA, [5]Christensen H, [6]Mary Elizabeth Ramsay, [7]Robert Heyderman [Full author list] | Epidemiology and Infection [curation] | DOI: 10.1017/S0950268805005595
PubMed: 16638165 | meningitis [curation]; epidemiology [curation]; bacterial meningitis [curation] | 2006-06-01 |
| Mucosal immunity and optimizing protection with meningococcal serogroup B vaccines | [1]Robert Heyderman, [2]Victoria Davenport, [3]Neil A Williams [Full author list] | Trends in Microbiology [curation] | DOI: 10.1016/J.TIM.2006.01.007
PubMed: 16469496 | | 2006-02-15 |
| Clinical manifestations of nontuberculous mycobacteria | [1]Robert Heyderman, [2]Julia Clark [Full author list] | Advances in Experimental Medicine and Biology [curation] | DOI: 10.1007/0-387-33026-7_14
PubMed: 16802627 | | 2006-01-01 |
| Spinal anesthesia with an indwelling catheter reduces the stress response in pediatric open heart surgery | [1]Nigel Humphreys, [2]Simon M Bays, [3]Andrew J Parry, [4]Ashwinikumar Pawade, [5]Robert Heyderman, [6]Andrew R Wolf [Full author list] | Anesthesiology [curation] | DOI: 10.1097/00000542-200512000-00003
PubMed: 16306721 | neurosurgery [curation]; cardiac surgery [curation] | 2005-12-01 |
| Lumbar puncture in the management of adults with suspected bacterial meningitis--a survey of practice | [1]Tristan Clark, [2]Erika Duffell, [3]James M Stuart, [4]Robert Heyderman [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2005.07.025
PubMed: 16209888 | meningitis [curation] | 2005-10-04 |
| Critical determinants of the interactions of capsule-expressing Neisseria meningitidis with host cells: the role of receptor density in increased cellular targeting via the outer membrane Opa proteins | [1]Christopher J Bradley, [2]Natalie J Griffiths, [3]Helen A Rowe, [4]Robert Heyderman, [5]Mumtaz Virji [Full author list] | Cellular Microbiology [curation] | DOI: 10.1111/J.1462-5822.2005.00572.X
PubMed: 16153247 | Neisseria meningitidis [curation] | 2005-10-01 |
| Early management of suspected bacterial meningitis and meningococcal septicaemia in immunocompetent adults--second edition | [1]Robert Heyderman, [2]British Infection Society [Full author list] | Journal of Infection [curation] | DOI: 10.1016/J.JINF.2005.04.002
PubMed: 15991345 | meningitis [curation]; sepsis [curation]; bacterial meningitis [curation] | 2005-06-01 |
| Influence of age and carriage status on salivary IgA to Neisseria meningitidis | [1]R E Horton, [2]J Stuart, [3]H Christensen, [4]R Borrow, [5]T Guthrie, [6]V Davenport, [7]A Finn, [8]N A Williams, [9]Robert Heyderman, [10]ALSPAC Study Team [Full author list] | Epidemiology and Infection [curation] | DOI: 10.1017/S0950268805004097
PubMed: 16181509 | Neisseria meningitidis [curation] | 2005-04-25 |
| Managing acute cystitis in women | [1]Tom Fahey, [2]Emma Webb, [3]Alan Montgomery, [4]Robert Heyderman [Full author list] | Family Practice [curation] | DOI: 10.1093/FAMPRA/CMH222
PubMed: 15020396 | urinary tract infection [curation] | 2004-04-01 |
| Capture-recapture analysis and pneumococcal meningitis estimates in England | [1]Ardiana Gjini, [2]James M Stuart, [3]Robert C George, [4]Tom Nichols, [5]Robert Heyderman [Full author list] | Emerging Infectious Diseases [curation] | PubMed: 15078602 | meningitis [curation]; pneumococcal meningitis [curation]; capture-recapture [curation] | 2004-01-01 |
| Evidence for Naturally Acquired T Cell-Mediated Mucosal Immunity to Neisseria meningitidis | [1]Victoria Davenport, [2]Terry Guthrie, [3]Jamie Findlow, [4]Ray Borrow, [5]Neil A. Williams, [6]Robert Heyderman [Full author list] | Journal of Immunology [curation] | DOI: 10.4049/JIMMUNOL.171.8.4263
PubMed: 14530350 | immunology [curation]; Neisseria meningitidis [curation] | 2003-10-15 |
| Management of diagnostic uncertainty in children with possible meningitis: a qualitative study | [1]Cathy A. Brennan, [2]Maggie Somerset, [3]Stephen K. Granier, [4]Tom P. Fahey, [5]Robert Heyderman [Full author list] | British Journal of General Practice [curation] | PubMed: 14601339 | meningitis [curation]; Neisseria meningitidis serogroup B [curation] | 2003-08-01 |
| Severe meningococcal disease is characterized by early neutrophil but not platelet activation and increased formation and consumption of platelet-neutrophil complexes | [1]M J Peters, [2]Robert Heyderman, [3]Saul N Faust, [4]G L J Dixon, [5]David P Inwald, [6]N J Klein [Full author list] | Journal of Leukocyte Biology [curation] | DOI: 10.1189/JLB.1002509
PubMed: 12773504 | meningococcal disease [curation] | 2003-06-01 |
| Rapid emergence of resistance to penicillin and trimethoprim-sulphamethoxazole in invasive Streptococcus pneumoniae in Zimbabwe | [1]Lovemore Gwanzura, [2]Christopher Pasi, [3]Kusum J Nathoo, [4]James Hakim, [5]Innocent T Gangaidzo, [6]Jens Mielke, [7]Valerie J Robertson, [8]Robert Heyderman, [9]Peter R Mason [Full author list] | International Journal of Antimicrobial Agents [curation] | DOI: 10.1016/S0924-8579(03)00052-9
PubMed: 12791469 | Zimbabwe [curation]; Streptococcus pneumoniae [curation] | 2003-06-01 |
| Clinical management of urinary tract infection in women: a prospective cohort study | [1]Tom Fahey, [2]Emma Webb, [3]Alan A Montgomery, [4]Robert Heyderman [Full author list] | Family Practice [curation] | DOI: 10.1093/FAMPRA/20.1.1
PubMed: 12509362 | urinary tract infection [curation] | 2003-02-01 |
| Auditory- and somatosensory-evoked potentials in cerebral malaria and anaesthesia: a comparison | [1]C Thornton, [2]Robert Heyderman, [3]M Thorniley, [4]Nigel Curtis, [5]J Mielke, [6]G Pasvol, [7]D E F Newton [Full author list] | European Journal of Anaesthesiology [curation] | DOI: 10.1017/S0265021502001175
PubMed: 12463383 | malaria [curation]; cerebral malaria [curation] | 2002-10-01 |
| Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo | [1]Odile B Harrison, [2]Brian D Robertson, [3]Saul N Faust, [4]M A Jepson, [5]R D Goldin, [6]Michael Levin, [7]Robert Heyderman [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.70.9.5193-5201.2002
PubMed: 12183570 | Neisseria meningitidis [curation]; purpura fulminans [curation] | 2002-09-01 |
| Awareness of a hospital's antibiotic policy can be improved | [1]Levy A, [2]Campbell D, [3]Spencer R, [4]Robert Heyderman [Full author list] | The BMJ [curation] | DOI: 10.1136/BMJ.321.7257.384
PubMed: 10991570 | | 2000-08-01 |
| Disseminated intravascular coagulation and purpura fulminans secondary to infection | [1]Saul N Faust, [2]Robert Heyderman, [3]Michael Levin [Full author list] | Best Practice and Research: Clinical Haematology [curation] | DOI: 10.1053/BEHA.2000.0067
PubMed: 10942620 | disseminated intravascular coagulation [curation]; purpura fulminans [curation] | 2000-06-01 |
| Adults with cerebral malaria do not have sensory evoked responses typical of deep general anaesthesia | [1]Robert Heyderman, [2]C Thornton, [3]J Mielke, [4]Nigel Curtis, [5]M S Thorniley, [6]C J Green, [7]D E Newton, [8]G Pasvol [Full author list] | Transactions of the Royal Society of Tropical Medicine and Hygiene [curation] | DOI: 10.1016/S0035-9203(00)90268-2
PubMed: 10897363 | malaria [curation]; general anaesthesia [curation]; cerebral malaria [curation] | 2000-03-01 |
| Neutrophil response to Neisseria meningitidis: inhibition of adhesion molecule expression and phagocytosis by recombinant bactericidal/permeability-increasing protein (rBPI21) | [1]Robert Heyderman, [2]Ison CA, [3]Peakman M, [4]Levin M, [5]Klein NJ [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1086/314706
PubMed: 10191239 | Neisseria meningitidis [curation]; phagocytosis [curation] | 1999-05-01 |
| Platelet satellitism | [1]Peters M, [2]Robert Heyderman, [3]Klein NJ [Full author list] | The New England Journal of Medicine [curation] | DOI: 10.1056/NEJM199807093390218
PubMed: 9669908 | | 1998-07-01 |
| Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping | [1]Robert Heyderman, [2]M Goyal, [3]P Roberts, [4]S Ushewokunze, [5]S Zizhou, [6]Ben G. Marshall, [7]R Makombe, [8]J D Van Embden, [9]P R Mason, [10]R J Shaw [Full author list] | Thorax [curation] | DOI: 10.1136/THX.53.5.346
PubMed: 9708224 | Zimbabwe [curation]; tuberculosis [curation]; pulmonary tuberculosis [curation] | 1998-05-01 |
| Pleural tuberculosis in Harare, Zimbabwe: the relationship between human immunodeficiency virus, CD4 lymphocyte count, granuloma formation and disseminated disease | [1]Robert Heyderman, [2]R Makunike, [3]T Muza, [4]M Odwee, [5]G Kadzirange, [6]J Manyemba, [7]C Muchedzi, [8]B Ndemera, [9]Z A Gomo, [10]L K Gwanzura, [11]P R Mason [Full author list] | Tropical Medicine and International Health [curation] | DOI: 10.1046/J.1365-3156.1998.00167.X
PubMed: 9484963 | Zimbabwe [curation]; tuberculosis [curation]; pleural tuberculosis [curation] | 1998-01-01 |
| Detection of fibronectin expression by human endothelial cells using a enzyme-linked immunosorbent assay (ELISA): enzymatic degradation by activated plasminogen | [1]O A Daramola, [2]Robert Heyderman, [3]N J Klein, [4]G I Shennan, [5]M Levin [Full author list] | Journal of Immunological Methods [curation] | DOI: 10.1016/S0022-1759(96)00237-2
PubMed: 9075773 | ELISEA [curation] | 1997-03-01 |
| The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis | [1]N J Klein, [2]C A Ison, [3]M Peakman, [4]Michael Levin, [5]S Hammerschmidt, [6]M Frosch, [7]Robert Heyderman [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/173.1.172
PubMed: 8537655 | Neisseria meningitidis [curation] | 1996-01-01 |
| Assessment of the effect of candidate anti-inflammatory treatments on the interaction between meningococci and inflammatory cells in vitro in a whole blood model | [1]Chan B, [2]Kalabalikis P, [3]Klein N, [4]Robert Heyderman, [5]Michael Levin [Full author list] | Biotherapy (Dordrecht, Netherlands) [curation] | DOI: 10.1007/BF02620735
PubMed: 9012541 | whole blood [curation] | 1996-01-01 |
| Modulation of the endothelial procoagulant response to lipopolysaccharide and tumour necrosis factor-alpha in-vitro: the effects of dexamethasone, pentoxifylline, iloprost and a polyclonal anti-human IL-1 alpha antibody | [1]Robert Heyderman, [2]N J Klein, [3]O A Daramola, [4]M Levin [Full author list] | Inflammation Research [curation] | DOI: 10.1007/BF02032568
PubMed: 8564523 | pentoxifylline [curation]; lipopolysaccharide [curation]; dexamethasone [curation] | 1995-07-01 |
| Whole blood model of meningococcal bacteraemia--a method for exploring host-bacterial interactions | [1]Ison CA, [2]Robert Heyderman, [3]Klein NJ, [4]Peakman M, [5]Levin M [Full author list] | Microbial Pathogenesis [curation] | DOI: 10.1016/S0882-4010(95)90093-4
PubMed: 7643746 | whole blood [curation] | 1995-02-01 |
| Haemolytic-uraemic syndrome | [1]Robert Heyderman, [2]M M Fitzpatrick, [3]G R Barclay [Full author list] | The Lancet [curation] | DOI: 10.1016/S0140-6736(94)90165-1
PubMed: 7909074 | | 1994-04-01 |
| Management of meningococcal infections | [1]Klein NJ, [2]Robert Heyderman, [3]Levin M [Full author list] | British journal of hospital medicine [curation] | PubMed: 8364705 | | 1993-06-01 |
| Sepsis and intravascular thrombosis | [1]Heyderman RS, [1-Q60016666]Robert Heyderman [Full author list] | Archives of Disease in Childhood [curation] | DOI: 10.1136/ADC.68.5.621
PubMed: 8323328 | sepsis [curation]; thrombosis [curation] | 1993-05-01 |
| Detection of glycosaminoglycans on the surface of human umbilical vein endothelial cells using gold-conjugated poly-L-lysine with silver enhancement | [1]N J Klein, [2]G I Shennan, [3]Robert Heyderman, [4]M Levin [Full author list] | The Histochemical Journal [curation] | DOI: 10.1007/BF00159120
PubMed: 8491669 | | 1993-04-01 |
| Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay | [1]Robert Heyderman, [2]Nigel Klein, [3]G. I. Shennan, [4]Michael Levin [Full author list] | Thrombosis Research [curation] | DOI: 10.1016/0049-3848(92)90071-H
PubMed: 1440532 | endotoxins [curation]; anticoagulation [curation] | 1992-09-15 |
| Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils | [1]Nigel Klein, [2]G. I. Shennan, [3]Robert Heyderman, [4]Michael Levin [Full author list] | Journal of Cell Science [curation] | DOI: 10.1242/JCS.102.4.821
PubMed: 1429895 | endotoxins [curation] | 1992-08-01 |
| Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis | [1]Robert Heyderman, [2]N J Klein [Full author list] | Archives of Disease in Childhood [curation] | DOI: 10.1136/ADC.67.7.980
PubMed: 1519970 | | 1992-07-01 |
| Antibiotic choices for meningitis beyond the neonatal period | [1]Nigel Klein, [2]Robert Heyderman, [3]Michael Levin [Full author list] | Archives of Disease in Childhood [curation] | DOI: 10.1136/ADC.67.2.157
PubMed: 1543371 | antibiotic [curation]; meningitis [curation] | 1992-02-01 |
| Infectious diseases | [1]Robert Heyderman, [2]E Larson [Full author list] | Journal of the Royal College of Physicians of London [curation] | PubMed: 2066928 | | 1991-04-01 |
| Antibiotic treatment of suspected neonatal meningitis | [1]Robert Heyderman, [2]Michael Levin [Full author list] | Archives of Disease in Childhood [curation] | DOI: 10.1136/ADC.66.1.170
PubMed: 1994850 | meningitis [curation] | 1991-01-01 |
| Antibody imaging to locate a placental site trophoblastic tumour following a complete hydatidiform mole | [1]Robert Heyderman, [2]Begent RH, [3]Buckley RG, [4]Searle F, [5]Southall P, [6]Bagshawe KD [Full author list] | Journal of the Royal Society of Medicine [curation] | DOI: 10.1177/014107688908200519
PubMed: 2547064 | mole [curation]; complete hydatidiform mole [curation] | 1989-05-01 |