| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis | [1]Wei Gao, [2]Yuliang Zhang, [3]Hongjie Luo, [4]Min Niu, [5]Xiwang Zheng, [6]Wanglai Hu, [7]Jiajia Cui, [8]Xuting Xue, [9]Yunfeng Bo, [10]Fengsheng Dai, ..., [22]Changming An, [23]Teng Ma, [24]Lei Jin, [25]Wei Xu, [26]Yongyan Wu [Full author list] | Cell Death and Disease [curation] | DOI: 10.1038/S41419-020-03104-6
PubMed: 33106477 | laryngeal squamous cell carcinoma [curation] | 2020-10-26 |
| c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis | [1]Yu Chen Feng, [2]Xiaoying Liu, [3]Liu Teng, [4]Qiang Ji, [5]Yongyan Wu, [6]Jin Ming Li, [7]Wei Gao, [8]Yuan Yuan Zhang, [9]Ting La, [10]Hessam Tabatabaee, [11]Xu Guang Yan, [12]Muhammad Fairuz Jamaluddin, [13]Didi Zhang, [14]Su Tang Guo, [15]Rodney Scott, [16]Tao Liu, [17]Rick F Thorne, [18]Xu Dong Zhang, [19]Lei Jin [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-020-18735-8
PubMed: 33020477 | | 2020-10-05 |
| Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence | [1]Ben Sang, [2]Yuan Yuan Zhang, [3]Su Tang Guo, [4]Ling Fei Kong, [5]Qiong Cheng, [6]Guangzhi Liu, [7]Rick F Thorne, [8]Xu Dong Zhang, [9]Lei Jin, [10]Dr Mian Wu [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1805950115
PubMed: 30478051 | cellular senescence [curation] | 2018-12-11 |
| A p53-Responsive miRNA Network Promotes Cancer Cell Quiescence | [1]Ting La, [2]Guang Zhi Liu, [3]Margaret Farrelly, [4]Santosh K Katiyar, [5]Yu Chen Feng, [6]Yuan Yuan Zhang, [7]Simonne K Sherwin, [8]Hamed Yari, [9]Hessam Tabatabaee, [10]Xu Guang Yan, [11]Su Tang Guo, [12]Tao Liu, [13]Rick F Thorne, [14]Lei Jin, [15]Xu Dong Zhang [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-18-1886
PubMed: 30301840 | microRNA [curation] | 2018-10-09 |
| RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors | [1]Fu Xi Lei, [2]Lei Jin, [3]Xiao Ying Liu, [4]Fritz Lai, [5]Xu Guang Yan, [6]Margaret Farrelly, [7]Su Tang Guo, [8]Xin Han Zhao, [9]Xu Dong Zhang [Full author list] | Cell Death and Disease [curation] | DOI: 10.1038/S41419-018-0714-7
PubMed: 29880840 | | 2018-06-07 |
| ACTN4 regulates the stability of RIPK1 in melanoma. | [1]Yuan Yuan Zhang, [2]Hessam Tabataba, [3]Xiao Ying Liu, [4]Jia Yu Wang, [5]Xu Guang Yan, [6]Margaret Farrelly, [7]Chen Chen Jiang, [8]Su Tang Guo, [9]Tao Liu, [10]Hung-Ying Kao, [11]Rick F Thorne, [12]Xu Dong Zhang, [13]Lei Jin [Full author list] | Oncogene [curation] | DOI: 10.1038/S41388-018-0260-X
PubMed: 29706658 | | 2018-04-30 |
| GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability | [1]Wang Lai Hu, [2]Lei Jin, [3]An Xu, [4]Yu Fang Wang, [5]Rick F Thorne, [6]Xu Dong Zhang, [7]Dr Mian Wu [Full author list] | Nature Cell Biology [curation] | DOI: 10.1038/S41556-018-0066-7
PubMed: 29593331 | non-coding RNA [curation] | 2018-03-28 |
| LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect | [1]Shaoxun Xiang, [2]Hao Gu, [3]Lei Jin, [4]Rick F Thorne, [5]Xu Dong Zhang, [6]Dr Mian Wu [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1711257115
PubMed: 29378948 | | 2018-01-29 |
| Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells | [1]Yu Fang Wang, [2]Fen Liu, [3]Simonne Sherwin, [4]Margaret Farrelly, [5]Xu Guang Yan, [6]Amanda Croft, [7]Tao Liu, [8]Lei Jin, [9]Xu Dong Zhang, [10]Chen Chen Jiang [Full author list] | Journal of Investigative Dermatology [curation] | DOI: 10.1016/J.JID.2017.11.009
PubMed: 29174371 | | 2017-11-22 |
| BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922 | [1]Chun Yan Wang, [2]Su Tang Guo, [3]Amanda Croft, [4]Xu Guang Yan, [5]Lei Jin, [6]Xu Dong Zhang, [7]Chen Chen Jiang [Full author list] | Molecular Carcinogenesis [curation] | DOI: 10.1002/MC.22755
PubMed: 29068469 | colon cancer [curation] | 2017-11-14 |
| Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress | [1]Jia Yu Wang, [2]Guang Zhi Liu, [3]James S Wilmott, [4]Ting La, [5]Yu Chen Feng, [6]Hamed Yari, [7]Xu Guang Yan, [8]Rick F Thorne, [9]Richard Scolyer, [10]Xu Dong Zhang, [11]Lei Jin [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-17-1965
PubMed: 28947420 | | 2017-09-25 |
| MicroRNA-645 is an oncogenic regulator in colon cancer | [1]S T Guo, [2]X Y Guo, [3]J Wang, [4]C Y Wang, [5]R H Yang, [6]F H Wang, [7]X Y Li, [8]H Hondermarck, [9]R F Thorne, [10]Y F Wang, [11]Lei Jin, [12]Xu Dong Zhang, [13]C C Jiang [Full author list] | Oncogenesis [curation] | DOI: 10.1038/ONCSIS.2017.37
PubMed: 28504690 | | 2017-05-15 |
| BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma | [1]Fen Liu, [2]Chen Chen Jiang, [3]Xu Guang Yan, [4]Hsin-Yi Tseng, [5]Chun Yan Wang, [6]Yuan Yuan Zhang, [7]Hamed Yari, [8]Ting La, [9]Margaret Farrelly, [10]Su Tang Guo, [11]Rick F Thorne, [12]Lei Jin, [13]Qi Wang, [14]Xu Dong Zhang [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.17704
PubMed: 29050218 | | 2017-05-09 |
| Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922 | [1]Chun Yan Wang, [2]Su Tang Guo, [3]Jia Yu Wang, [4]Xu Guang Yan, [5]Margaret Farrelly, [6]Yuan Yuan Zhang, [7]Fen Liu, [8]Hamed Yari, [9]Ting La, [10]Fu Xi Lei, [11]Lei Jin, [12]Xu Dong Zhang, [13]Chen Chen Jiang [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.10414
PubMed: 27391062 | colon cancer [curation] | 2016-08-01 |
| Reactive Oxygen Species Dictate the Apoptotic Response of Melanoma Cells to TH588. | [1]Jia Yu Wang, [2]Lei Jin, [3]Xu Guang Yan, [4]Simonne Sherwin, [5]Margaret Farrelly, [6]Yuan Yuan Zhang, [7]Fen Liu, [8]Chun Yan Wang, [9]Su Tang Guo, [10]Hamed Yari, [11]Ting La, [12]Jennifer McFarlane, [13]Fu Xi Lei, [14]Hessam Tabatabaee, [15]Jie Zhong Chen, [16]Amanda Croft, [17]Chen Chen Jiang, [18]Xu Dong Zhang [Full author list] | Journal of Investigative Dermatology [curation] | DOI: 10.1016/J.JID.2016.06.625
PubMed: 27427486 | reactive oxygen species [curation]; apoptotic process [curation] | 2016-07-14 |
| Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress | [1]Chun Yan Wang, [2]Su Tang Guo, [3]Jia Yu Wang, [4]Fen Liu, [5]Yuan Yuan Zhang, [6]Hamed Yari, [7]Xu Guang Yan, [8]Lei Jin, [9]Xu Dong Zhang, [10]Chen Chen Jiang [Full author list] | Molecular Cancer Therapeutics [curation] | DOI: 10.1158/1535-7163.MCT-15-0778
PubMed: 26832792 | colon cancer [curation] | 2016-02-01 |
| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | [1]Daniel J. Klionsky, [2]Kotb Abdelmohsen, [3]Akihisa Abe, [4]Md Joynal Abedin, [5]Hagai Abeliovich, [6]Abraham Acevedo-Arozena, [7]Hiroaki Adachi, [8]Christopher M Adams, [9]Peter D Adams, [10]Khosrow Adeli, ..., [934]Cheng Jin, [935]Hongchuan Jin, [936]Lei Jin, [937]Meiyan Jin, [938]Shengkan V. Jin, ... [Full author list] | Autophagy [curation] | DOI: 10.1080/15548627.2015.1100356
PubMed: 26799652 | cell biology [curation]; autophagy [curation] | 2016-01-02 |
| Regulation of PD-L1: a novel role of pro-survival signalling in cancer | [1]J Chen, [2]C C Jiang, [3]Lei Jin, [4]Xu Dong Zhang [Full author list] | Annals of Oncology [curation] | DOI: 10.1093/ANNONC/MDV615
PubMed: 26681673 | | 2015-12-17 |
| INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas | [1]Meng Na Chi, [2]Su Tang Guo, [3]James S Wilmott, [4]Xiang Yun Guo, [5]Xu Guang Yan, [6]Chun Yan Wang, [7]Xiao Ying Liu, [8]Lei Jin, [9]Hsin-Yi Tseng, [10]Tao Liu, [11]Amanda Croft, [12]Hubert Hondermarck, [13]Richard Scolyer, [14]Chen Chen Jiang, [15]Xu Dong Zhang [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.5359
PubMed: 26573229 | | 2015-11-01 |
| INPP4B is an oncogenic regulator in human colon cancer | [1]S T Guo, [2]M N Chi, [3]R H Yang, [4]X Y Guo, [5]L K Zan, [6]C Y Wang, [7]Y F Xi, [8]Lei Jin, [9]A Croft, [10]H-Y Tseng, ... [Full author list] | Oncogene [curation] | DOI: 10.1038/ONC.2015.361
PubMed: 26411369 | | 2015-09-28 |
| The double life of RIPK1 | [1]Lei Jin, [2]Jiezhong Chen, [3]Xiao Ying Liu, [4]Chen Chen Jiang, [5]Xu Dong Zhang [Full author list] | Molecular & cellular oncology [curation] | DOI: 10.1080/23723556.2015.1035690
PubMed: 27308554 | | 2015-05-26 |
| RIP1 Kinase Is an Oncogenic Driver in Melanoma | [1]Xiao Ying Liu, [2]Fritz Lai, [3]Xu Guang Yan, [4]Chen Chen Jiang, [5]Su Tang Guo, [6]Chun Yan Wang, [7]Amanda Croft, [8]Hsin-Yi Tseng, [9]James S Wilmott, [10]Richard Scolyer, [11]Lei Jin, [12]Xu Dong Zhang [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-14-2199
PubMed: 25724678 | | 2015-02-27 |
| RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy | [1]Qi Luan, [2]Lei Jin, [3]Chen Chen Jiang, [4]Kwang Hong Tay, [5]Fritz Lai, [6]Xiao Ying Liu, [7]Yi Lun Liu, [8]Su Tang Guo, [9]Chun Ying Li, [10]Xu Guang Yan, [11]Hsin-Yi Tseng, [12]Xu Dong Zhang [Full author list] | Autophagy [curation] | DOI: 10.1080/15548627.2015.1049800
PubMed: 26018731 | endoplasmic reticulum [curation]; autophagy [curation] | 2015-01-01 |
| Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720 | [1]Kwang Hong Tay, [2]Xiaoying Liu, [3]Mengna Chi, [4]Lei Jin, [5]Chen Chen Jiang, [6]Su Tang Guo, [7]Nicole M Verrills, [8]Hsin-Yi Tseng, [9]Xu Dong Zhang [Full author list] | Pigment Cell & Melanoma Research [curation] | DOI: 10.1111/PCMR.12326
PubMed: 25358761 | | 2014-11-13 |
| Phenotypic characterization and risk factors for microtia in East China, a case-control study | [1]Chen-long Li, [2]Ying Chen, [3]Jin Shan, [4]Shao-juan Hao, [5]Lei Jin, [6]Feng-hua Qing, [7]Tian-yu Zhang [Full author list] | International Journal of Pediatric Otorhinolaryngology [curation] | DOI: 10.1016/J.IJPORL.2014.09.001
PubMed: 25281337 | microtia [curation] | 2014-09-11 |
| The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells | [1]Stuart J. Gallagher, [2]Branka Mijatov, [3]Dilini Gunatilake, [4]Jessamy C Tiffen, [5]Kavitha Gowrishankar, [6]Lei Jin, [7]Gulietta M Pupo, [8]Carleen Cullinane, [9]Rab K Prinjha, [10]Nicholas Smithers, [11]Grant McArthur, [12]Helen Rizos, [13]Peter Hersey [Full author list] | Journal of Investigative Dermatology [curation] | DOI: 10.1038/JID.2014.243
PubMed: 24906137 | apoptotic process [curation] | 2014-06-06 |
| Adipocytes contribute to resistance of human melanoma cells to chemotherapy and targeted therapy | [1]M Chi, [2]J Chen, [3]Y Ye, [4]Hsin-Yi Tseng, [5]F Lai, [6]K H Tay, [7]Lei Jin, [8]S T Guo, [9]C C Jiang, [10]Xu Dong Zhang [Full author list] | Current Medicinal Chemistry [curation] | DOI: 10.2174/0929867321666131129114742
PubMed: 24304284 | | 2014-04-01 |
| Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress | [1]Kwang Hong Tay, [2]Qi Luan, [3]Amanda Croft, [4]Chen Chen Jiang, [5]Lei Jin, [6]Xu Dong Zhang, [7]Hsin-Yi Tseng [Full author list] | Cellular Signalling [curation] | DOI: 10.1016/J.CELLSIG.2013.11.008
PubMed: 24240056 | | 2013-11-12 |
| AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma | [1]W Hu, [2]Lei Jin, [3]C C Jiang, [4]Georgina V. Long, [5]Richard Scolyer, [6]Q Wu, [7]Xu Dong Zhang, [8]Y Mei, [9]M Wu [Full author list] | Cell Death and Disease [curation] | DOI: 10.1038/CDDIS.2013.441
PubMed: 24201813 | | 2013-11-07 |
| Oncogenic suppression of PHLPP1 in human melanoma | [1]L Dong, [2]Lei Jin, [3]Hsin-Yi Tseng, [4]C Y Wang, [5]J S Wilmott, [6]B Yosufi, [7]X G Yan, [8]C C Jiang, [9]Richard Scolyer, [10]Xu Dong Zhang, [11]S T Guo [Full author list] | Oncogene [curation] | DOI: 10.1038/ONC.2013.420
PubMed: 24121273 | | 2013-10-14 |
| Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress | [1]Amanda Croft, [2]Kwang H Tay, [3]Suzanah C Boyd, [4]Su T Guo, [5]Chen C Jiang, [6]Fritz Lai, [7]Hsin-Yi Tseng, [8]Lei Jin, [9]Helen Rizos, [10]Peter Hersey, [11]Xu Dong Zhang [Full author list] | Journal of Investigative Dermatology [curation] | DOI: 10.1038/JID.2013.325
PubMed: 23921951 | endoplasmic reticulum [curation] | 2013-08-06 |
| Loss of PI(4,5)P2 5-Phosphatase A Contributes to Resistance of Human Melanoma Cells to RAF/MEK Inhibitors | [1]Yan Ye, [2]Qun Li, [3]Wang Lai Hu, [4]Hsin-Yi Tseng, [5]Lei Jin, [6]Xu Dong Zhang, [7]Lin Jie Zhang, [8]Sen Yang [Full author list] | Translational Oncology [curation] | DOI: 10.1593/TLO.13277
PubMed: 23908690 | | 2013-08-01 |
| Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3 | [1]F Lai, [2]S T Guo, [3]Lei Jin, [4]C C Jiang, [5]C Y Wang, [6]A Croft, [7]M N Chi, [8]H-Y Tseng, [9]M Farrelly, [10]B Atmadibrata, [11]J Norman, [12]Tao Liu, [13]P Hersey, [14]Xu Dong Zhang [Full author list] | Cell Death and Disease [curation] | DOI: 10.1038/CDDIS.2013.192
PubMed: 23744355 | | 2013-06-06 |
| Endoplasmic reticulum stress inhibits cell cycle progression via induction of p27 in melanoma cells | [1]Chuanchun Han, [2]Lei Jin, [3]Yide Mei, [4]Dr Mian Wu [Full author list] | Cellular Signalling [curation] | DOI: 10.1016/J.CELLSIG.2012.09.023
PubMed: 23010535 | endoplasmic reticulum [curation] | 2012-09-23 |
| The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells | [1]Hsin-Yi Tseng, [2]Li Hua Chen, [3]Yan Ye, [4]Kwang Hong Tay, [5]Chen Chen Jiang, [6]Su Tang Guo, [7]Lei Jin, [8]Peter Hersey, [9]Xu Dong Zhang [Full author list] | Carcinogenesis [curation] | DOI: 10.1093/CARCIN/BGS236
PubMed: 22791814 | apoptotic process [curation] | 2012-07-12 |
| p53-facilitated miR-199a-3p regulates somatic cell reprogramming | [1]Jiaxu Wang, [2]Qianqian He, [3]Chuanchun Han, [4]Hao Gu, [5]Lei Jin, [6]Qun Li, [7]Yide Mei, [8]Dr Mian Wu [Full author list] | Stem Cells [curation] | DOI: 10.1002/STEM.1121
PubMed: 22553189 | | 2012-07-01 |
| MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer | [1]S T Guo, [2]C C Jiang, [3]G P Wang, [4]Y P Li, [5]C Y Wang, [6]X Y Guo, [7]R H Yang, [8]Y Feng, [9]F H Wang, [10]H-Y Tseng, [11]R F Thorne, [12]Lei Jin, [13]Xu Dong Zhang [Full author list] | Oncogene [curation] | DOI: 10.1038/ONC.2012.214
PubMed: 22710713 | colorectal cancer [curation]; microRNA [curation]; preproinsulin [curation]; colorectal carcinoma [curation] | 2012-06-18 |
| Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors | [1]Fritz Lai, [2]Lei Jin, [3]Stuart J. Gallagher, [4]Branka Mijatov, [5]Xu Dong Zhang, [6]Peter Hersey [Full author list] | Advances in Pharmacology [curation] | DOI: 10.1016/B978-0-12-397927-8.00002-6
PubMed: 22959022 | | 2012-01-01 |
| MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma | [1]Lei Jin, [2]Wang Lai Hu, [3]Chen Chen Jiang, [4]Jia Xu Wang, [5]Chuan Chun Han, [6]Ping Chu, [7]Lin Jie Zhang, [8]Rick F Thorne, [9]James Wilmott, [10]Richard Scolyer, [11]Peter Hersey, [12]Xu Dong Zhang, [13]Dr Mian Wu [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1019312108
PubMed: 21896753 | microRNA [curation] | 2011-09-06 |
| Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF) | [1]Su Qin, [2]Lei Jin, [3]Jiahai Zhang, [4]Lei Liu, [5]Peng Ji, [6]Mian Wu, [7]Jihui Wu, [8]Yunyu Shi [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M111.244400
PubMed: 21880731 | cell biology [curation]; leukemia [curation]; histone binding [curation]; Bromodomain containing 1 [curation] | 2011-08-31 |
| E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1 | [1]Wei Xie, [2]Lei Jin, [3]Yide Mei, [4]Dr Mian Wu [Full author list] | Journal of Cellular and Molecular Medicine [curation] | DOI: 10.1111/J.1582-4934.2008.00423.X
PubMed: 20187294 | | 2009-08-01 |