| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification | [1]Zhenzhen Zi, [2]Zhuzhen Zhang, [3]Qiang Feng, [4]Chiho Kim, [5]Xu-Dong Wang, [6]Philipp E. Scherer, [7]Jinming Gao, [8]Beth Levine, [9]Yonghao Yu [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-022-29461-8
| | 2022-04-01 |
| Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders | [1]Ilja L. Kruglikov, [2]Zhuzhen Zhang, [3]Philipp E. Scherer [Full author list] | International Journal of Molecular Sciences [curation] | DOI: 10.3390/IJMS23073828
| | 2022-03-30 |
| Adiponectin and cardiometabolic trait and mortality: where do we go? | [1]Albert Youngwoo Jang, [2]Philipp E. Scherer, [3]Jang Young Kim, [4]Soo Lim, [5]Kwang Kon Koh [Full author list] | Cardiovascular Research [curation] | DOI: 10.1093/CVR/CVAB199
| | 2021-06-12 |
| A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21 | [1]Myoung Sook Han, [2]Rachel J Perry, [3]João Paulo Camporez, [4]Philipp E. Scherer, [5]Gerald I. Shulman, [6]Guangping Gao, [7]Roger John Davis [Full author list] | Genes & Development [curation] | DOI: 10.1101/GAD.344556.120
PubMed: 33334822 | | 2020-12-17 |
| Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans | [1]Maria Apostolopoulou, [2]Ruth Gordillo, [3]Sofiya Gancheva, [4]Klaus Strassburger, [5]Christian Herder, [6]Irene Esposito, [7]Matthias Schlensak, [8]Philipp E. Scherer, [9]Michael Roden [Full author list] | BMJ open diabetes research & care [curation] | DOI: 10.1136/BMJDRC-2020-001860
PubMed: 33219119 | insulin resistance [curation]; metabolic dysfunction–associated steatotic liver disease [curation]; non-alcoholic fatty liver [curation] | 2020-11-01 |
| The impact of endotrophin on the progression of chronic liver disease | [1]Min Kim, [2]Changhu Lee, [3]Dae Yun Seo, [4]Hyojung Lee, [5]Jay D Horton, [6]Jiyoung Park, [7]Philipp E. Scherer [Full author list] | Experimental and Molecular Medicine [curation] | DOI: 10.1038/S12276-020-00520-8
PubMed: 33110211 | chronic liver disease [curation] | 2020-10-27 |
| Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral-bacterial interactions | [1]Ilja L Kruglikov, [2]Manasi Shah, [3]Philipp E. Scherer [Full author list] | eLife [curation] | DOI: 10.7554/ELIFE.61330
PubMed: 32930095 | comorbidity [curation]; COVID-19 [curation] | 2020-09-15 |
| Dermal adipocytes contribute to the metabolic regulation of dermal fibroblasts | [1]Zhuzhen Zhang, [2]Ilja Kruglikov, [3]Shangang Zhao, [4]Zhenzhen Zi, [5]Christy M Gliniak, [6]Na Li, [7]May-Yun Wang, [8]Qingzhang Zhu, [9]Christine M Kusminski, [10]Philipp E. Scherer [Full author list] | Experimental Dermatology [curation] | DOI: 10.1111/EXD.14181
PubMed: 32866299 | | 2020-08-31 |
| The MMP14-caveolin axis and its potential relevance for lipoedema | [1]Ilja L Kruglikov, [2]Nolwenn Joffin, [3]Philipp E. Scherer [Full author list] | Nature Reviews Endocrinology [curation] | DOI: 10.1038/S41574-020-0395-Z
PubMed: 32792644 | | 2020-08-13 |
| PHOSPHO1 puts the breaks on thermogenesis in brown adipocytes | [1]Christy M Gliniak, [2]Philipp E. Scherer [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.2011052117
PubMed: 32641502 | adipocyte [curation]; thermogenesis [curation] | 2020-07-08 |
| Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome | [1]Zhao Zhang, [2]Thomas Gallagher, [3]Philipp E. Scherer, [4]Bruce Beutler [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.2000118117
PubMed: 32381739 | adipocyte [curation] | 2020-05-07 |
| Leptin: Less Is More | [1]Shangang Zhao, [2]Christine M Kusminski, [3]Joel K Elmquist, [4]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DBI19-0018
PubMed: 32312898 | | 2020-05-01 |
| The role of adipocytes and adipocyte-like cells in the severity of COVID-19 infections | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Obesity [curation] | DOI: 10.1002/OBY.22856
PubMed: 32339391 | adipocyte [curation]; COVID-19 [curation] | 2020-04-27 |
| Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection | [1]Paul Zaki, [2]Elisa L B C Domingues, [3]Farhad M Amjad, [4]Maiara B Narde, [5]Karolina R Gonçalves, [6]Mirelle L Viana, [7]Heberth de Paula, [8]Wanderson G de Lima, [9]Huan Huang, [10]Maria T Bahia, [11]Philipp E. Scherer, [12]Fabiane M Dos Santos, [13]Louis M Weiss, [14]Herbert B Tanowitz [Full author list] | Parasitology Research [curation] | DOI: 10.1007/S00436-020-06685-5
PubMed: 32307581 | Trypanosoma cruzi [curation] | 2020-04-20 |
| Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer | [1]Line Pedersen, [2]Pouda Panahandeh, [3]Muntequa I Siraji, [4]Stian Knappskog, [5]Per Eystein Lønning, [6]Ruth Gordillo, [7]Philipp E. Scherer, [8]Anders Molven, [9]Knut Teigen, [10]Nils Halberg [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-19-3177
PubMed: 32291319 | apoptotic process [curation] | 2020-04-14 |
| Partial leptin deficiency confers resistance to diet-induced obesity in mice | [1]Shangang Zhao, [2]Na Li, [3]Yi Zhu, [4]Leon Straub, [5]Zhuzhen Zhang, [6]May-Yun Wang, [7]Qingzhang Zhu, [8]Christine M Kusminski, [9]Joel K Elmquist, [10]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2020.100995
PubMed: 32289482 | | 2020-04-11 |
| Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity | [1]Xin Li, [2]Yueshui Zhao, [3]Chuan Chen, [4]Li Yang, [5]Hyun-Ho Lee, [6]Zening Wang, [7]Ningyan Zhang, [8]Mikhail G Kolonin, [9]Zhiqiang An, [10]Xin Ge, [11]Philipp E. Scherer, [12]Kai Sun [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00564-19
PubMed: 31988105 | | 2020-03-30 |
| Induction of Effective Immunity against Trypanosoma cruzi | [1]Tere Williams, [2]Ignacio Guerrero-Ros, [3]Yanfen Ma, [4]Fabiane Matos Dos Santos, [5]Philipp E. Scherer, [6]Ruth Gordillo, [7]Aline Horta, [8]Fernando Macian, [9]Louis M Weiss, [10]Huan Huang [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.00908-19
PubMed: 31907197 | Trypanosoma cruzi [curation] | 2020-03-23 |
| Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue | [1]Anying Song, [2]Wenting Dai, [3]Min Jee Jang, [4]Leonard Medrano, [5]Zhuo Li, [6]Hu Zhao, [7]Mengle Shao, [8]Jiayi Tan, [9]Aimin Li, [10]Tinglu Ning, [11]Marcia M Miller, [12]Brian Armstrong, [13]Janice M Huss, [14]Yi Zhu, [15]Yong Liu, [16]Viviana Gradinaru, [17]Xiwei Wu, [18]Lei Jiang, [19]Philipp E. Scherer, [20]Qiong A Wang [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI129167
PubMed: 31573981 | adipocyte [curation] | 2020-01-01 |
| A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia | [1]Christine M Kusminski, [2]Alexandra L Ghaben, [3]Thomas S Morley, [4]Ricardo J Samms, [5]Andrew C Adams, [6]Yu An, [7]Joshua A Johnson, [8]Nolwenn Joffin, [9]Toshiharu Onodera, [10]Clair Crewe, [11]William L Holland, [12]Ruth Gordillo, [13]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB19-0327
PubMed: 31882562 | adipocyte [curation] | 2019-12-27 |
| Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress | [1]Vasiliki Delitsikou, [2]George Jarad, [3]Renuga Devi Rajaram, [4]Frédérique Ino, [5]Joseph M. Rutkowski, [6]Ci-Di Chen, [7]Celio X C Santos, [8]Philipp E. Scherer, [9]Carmela R Abraham, [10]Ajay M Shah, [11]Eric Feraille, [12]Jeffrey H Miner, [13]Sophie de Seigneux [Full author list] | FASEB Journal [curation] | DOI: 10.1096/FJ.201900893R
PubMed: 31907991 | endoplasmic reticulum [curation] | 2019-12-23 |
| Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity | [1]Yu A An, [2]Clair Crewe, [3]Ingrid Wernstedt Asterholm, [4]Kai Sun, [5]Shiuhwei Chen, [6]Fang Zhang, [7]Mengle Shao, [8]Jan-Bernd Funcke, [9]Zhuzhen Zhang, [10]Leon Straub, [11]Samuel Klein, [12]Christine M Kusminski, [13]Philipp E. Scherer [Full author list] | | DOI: 10.1038/S42255-019-0149-1
PubMed: 31984308 | | 2019-12-13 |
| Caveolin-1 as a possible target in the treatment for acne | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Experimental Dermatology [curation] | DOI: 10.1111/EXD.14063
PubMed: 31769542 | | 2019-12-09 |
| Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice | [1]Zhuzhen Zhang, [2]Mengle Shao, [3]Chelsea Hepler, [4]Zhenzhen Zi, [5]Shangang Zhao, [6]Yu An, [7]Yi Zhu, [8]Alexandra L Ghaben, [9]May-Yun Wang, [10]Na Li, ..., [23]Christine M Kusminski, [24]Rana K Gupta, [25]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI130239
PubMed: 31503545 | | 2019-12-01 |
| Imaging Metabolically Active Fat: A Literature Review and Mechanistic Insights | [1]Joseph Frankl, [1-Q47256640]Joseph Frankl, [2]Amber Sherwood, [3]Deborah J. Clegg, [3-Q98394748]Deborah J. Clegg, [4]Philipp E. Scherer, [4-Q60572448]Philipp E. Scherer, [5]Orhan K. Öz, [5-Q59750760]Orhan Oz [Full author list] | International Journal of Molecular Sciences [curation] | DOI: 10.3390/IJMS20215509
PubMed: 31694216 | | 2019-11-05 |
| Obesity dysregulates fasting-induced changes in glucagon secretion | [1]Jennifer H Stern, [2]Gordon I Smith, [3]Shiuwei Chen, [4]Roger H Unger, [5]Samuel Klein, [6]Philipp E. Scherer [Full author list] | Journal of Endocrinology [curation] | DOI: 10.1530/JOE-19-0201
PubMed: 31454790 | glucagon [curation] | 2019-11-01 |
| Cellular Origins of Beige Fat Cells Revisited | [1]Mengle Shao, [2]Qiong A Wang, [3]Anying Song, [4]Lavanya Vishvanath, [5]Napoleon C Busbuso, [6]Philipp E. Scherer, [7]Rana K Gupta [Full author list] | Diabetes [curation] | DOI: 10.2337/DB19-0308
PubMed: 31540940 | | 2019-10-01 |
| Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution | [1]Qiong A Wang, [2]Philipp E. Scherer [Full author list] | Journal of Mammary Gland Biology and Neoplasia [curation] | DOI: 10.1007/S10911-019-09434-2
PubMed: 31512027 | | 2019-09-12 |
| Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy | [1]Shangang Zhao, [2]Yi Zhu, [3]Robbie D Schultz, [4]Na Li, [5]Zhenyan He, [6]Zhuzhen Zhang, [7]Alexandre Caron, [8]Qingzhang Zhu, [9]Kai Sun, [10]Wei Xiong, ..., [23]Kevin W Williams, [24]Zhiqiang An, [25]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2019.08.005
PubMed: 31495688 | | 2019-09-05 |
| Caveolin-1 in skin aging - From innocent bystander to major contributor | [1]Ilja L Kruglikov, [2]Zhuzhen Zhang, [3]Philipp E. Scherer [Full author list] | Ageing Research Reviews [curation] | DOI: 10.1016/J.ARR.2019.100959
PubMed: 31493519 | | 2019-09-04 |
| Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation | [1]Silvia Ferrè, [2]Yingfeng Deng, [3]Sarah C Huen, [4]Christopher Y Lu, [5]Philipp E. Scherer, [6]Peter Igarashi, [7]Orson W Moe [Full author list] | Kidney International [curation] | DOI: 10.1016/J.KINT.2019.06.023
PubMed: 31601454 | acute kidney injury [curation] | 2019-08-01 |
| SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1 | [1]Clair Crewe, [2]Yi Zhu, [3]Vivian A Paschoal, [4]Nolwenn Joffin, [5]Alexandra L Ghaben, [6]Ruth Gordillo, [7]Da Young Oh, [8]Guosheng Liang, [9]Jay D Horton, [10]Philipp E. Scherer [Full author list] | JCI insight [curation] | DOI: 10.1172/JCI.INSIGHT.129397
PubMed: 31310592 | adipocyte [curation] | 2019-07-16 |
| Lowering ceramides to overcome diabetes | [1]Christine M Kusminski, [2]Philipp E. Scherer [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.AAX6594
PubMed: 31346052 | ceramides [curation] | 2019-07-01 |
| XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia | [1]Gang Chen, [2]Carla M P Ribeiro, [3]Ling Sun, [4]Kenichi Okuda, [5]Takafumi Kato, [6]Rodney C Gilmore, [7]Mary B Martino, [8]Hong Dang, [9]Aiman Abzhanova, [10]Jennifer M Lin, [11]Emily A Hull-Ryde, [12]Allison S Volmer, [13]Scott H Randell, [14]Alessandra Livraghi-Butrico, [15]Yingfeng Deng, [16]Philipp E. Scherer, [17]Barry R Stripp, [18]Wanda K O'Neal, [19]Richard C Boucher [Full author list] | American Journal of Respiratory and Critical Care Medicine [curation] | DOI: 10.1164/RCCM.201810-1972OC
PubMed: 30973754 | pulmonary fibrosis [curation]; idiopathic pulmonary fibrosis [curation] | 2019-07-01 |
| Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis | [1]Alexandre Caron, [2]Ryan P Reynolds, [3]Carlos M Castorena, [4]Natalie J Michael, [5]Charlotte E Lee, [6]Syann Lee, [7]Rebecca Berdeaux, [8]Philipp E. Scherer, [9]Joel K Elmquist [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2019.06.019
PubMed: 31279640 | adipocyte [curation] | 2019-06-22 |
| Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication | [1]Jan-Bernd Funcke, [2]Philipp E. Scherer [Full author list] | Journal of Lipid Research [curation] | DOI: 10.1194/JLR.R094060
PubMed: 31209153 | | 2019-06-17 |
| Spliced X-box Binding Protein 1 Stimulates Adaptive Growth Through Activation of mTOR | [1]Xiaoding Wang, [2]Yingfeng Deng, [3]Guangyu Zhang, [4]Chao Li, [5]Guanqiao Ding, [6]Herman I May, [7]Diem Hong Tran, [8]Xiang Luo, [9]Ding-Sheng Jiang, [10]Dan L Li, [11]Xiang Wei, [12]Lin Xu, [13]Anwarul Ferdous, [14]Thomas G Gillette, [15]Philipp E. Scherer, [16]Xuejun Jiang, [17]Zhao V Wang [Full author list] | Circulation [curation] | DOI: 10.1161/CIRCULATIONAHA.118.038924
PubMed: 31177839 | | 2019-06-10 |
| Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood | [1]Christy M Gliniak, [2]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI128830
PubMed: 31081800 | breastfeeding [curation] | 2019-05-13 |
| Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism. | [1]Yi Zhu, [2]Ilja L Kruglikov, [3]Yucel Akgul, [4]Philipp E. Scherer [Full author list] | Matrix Biology [curation] | DOI: 10.1016/J.MATBIO.2018.02.012
PubMed: 29458140 | tissue engineering [curation]; adipogenesis [curation] | 2019-05-01 |
| Caveolin-1 as a target in prevention and treatment of hypertrophic scarring | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | NPG Regenerative Medicine [curation] | DOI: 10.1038/S41536-019-0071-X
PubMed: 31044089 | | 2019-04-26 |
| Adipogenesis and metabolic health | [1]Alexandra L Ghaben, [2]Philipp E. Scherer [Full author list] | Nature Reviews Molecular Cell Biology [curation] | DOI: 10.1038/S41580-018-0093-Z
PubMed: 30610207 | adipogenesis [curation] | 2019-04-01 |
| Human endotrophin as a driver of malignant tumor growth. | [1]Dawei Bu, [2]Clair Crewe, [3]Christine M Kusminski, [4]Ruth Gordillo, [5]Alexandra L Ghaben, [6]Min Kim, [7]Jiyoung Park, [8]Hui Deng, [9]Wei Xiong, [10]Xiao-Zheng Liu, [11]Per Eystein Lønning, [12]Nils Halberg, [13]Adan Rios, [14]Yujun Chang, [15]Anneliese Gonzalez, [16]Ningyan Zhang, [17]Zhiqiang An, [18]Philipp E. Scherer [Full author list] | JCI insight [curation] | DOI: 10.1172/JCI.INSIGHT.125094
PubMed: 30896449 | | 2019-03-21 |
| Metabolic Messengers: Adiponectin | [1]Leon G Straub, [2]Philipp E. Scherer [Full author list] | Nature Metabolism [curation] | DOI: 10.1038/S42255-019-0041-Z
PubMed: 32661510 | | 2019-03-14 |
| Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity | [1]Adri Chakraborty, [2]Sheridan Barajas, [3]Gabriela M Lammoglia, [4]Andrea J Reyna, [5]Thomas S Morley, [6]Joshua A Johnson, [7]Philipp E. Scherer, [8]Joseph M. Rutkowski [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2018.12.008
PubMed: 30878136 | | 2019-03-13 |
| High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice | [1]Poghni Peri-Okonny, [2]Kedryn K Baskin, [3]Gary Iwamoto, [4]Jere H Mitchell, [5]Scott A Smith, [6]Han Kyul Kim, [7]Luke I Szweda, [8]Rhonda Bassel-Duby, [9]Teppei Fujikawa, [10]Carlos M Castorena, [11]James Richardson, [12]John M Shelton, [13]Colby R Ayers, [14]Jarett D Berry, [15]Venkat S Malladi, [16]Ming-Chang Hu, [17]Orson W Moe, [18]Philipp E. Scherer, [19]Wanpen Vongpatanasin [Full author list] | Circulation [curation] | DOI: 10.1161/CIRCULATIONAHA.118.037550
PubMed: 30612451 | | 2019-03-01 |
| Caveolin-1 as a pathophysiological factor and target in psoriasis | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | NPJ aging and mechanisms of disease [curation] | DOI: 10.1038/S41514-019-0034-X
PubMed: 30729030 | pathophysiology [curation] | 2019-02-05 |
| Lipotoxicity and β Cell Maintenance in Obesity and Type 2 Diabetes | [1]Risheng Ye, [2]Toshiharu Onodera, [3]Philipp E. Scherer [Full author list] | Journal of the Endocrine Society [curation] | DOI: 10.1210/JS.2018-00372
PubMed: 30834357 | type 2 diabetes [curation]; Lipotoxicity [curation] | 2019-02-04 |
| β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis | [1]Risheng Ye, [2]Toshiharu Onodera, [3]Pierre-Gilles Blanchard, [4]Christine M Kusminski, [5]Victoria Esser, [6]Rolf Brekken, [7]Philipp E. Scherer [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2019.01.002
PubMed: 30653956 | autophagy [curation]; acute pancreatitis [curation] | 2019-01-14 |
| The Role of Immature and Mature Adipocytes in Hair Cycling | [1]Ilja L Kruglikov, [2]Zhuzhen Zhang, [3]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/J.TEM.2018.11.004
PubMed: 30558832 | | 2018-12-14 |
| The many secret lives of adipocytes: implications for diabetes | [1]Philipp E. Scherer [Full author list] | Diabetologia [curation] | DOI: 10.1007/S00125-018-4777-X
PubMed: 30465066 | adipocyte [curation] | 2018-11-21 |
| Utility of Adipocyte Fractions in Fat Grafting in an Athymic Rat Model | [1]Yucel Akgul, [2]Ryan Constantine, [3]Mason Bartels, [4]Philipp E. Scherer, [5]Kathryn Davis, [6]Jeffrey M Kenkel [Full author list] | Aesthetic Surgery Journal [curation] | DOI: 10.1093/ASJ/SJY111
PubMed: 29722790 | adipocyte [curation] | 2018-11-01 |
| An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State | [1]Clair Crewe, [2]Nolwenn Joffin, [3]Joseph M. Rutkowski, [4]Min Kim, [5]Fang Zhang, [6]Dwight A Towler, [7]Ruth Gordillo, [8]Philipp E. Scherer [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2018.09.005
PubMed: 30293865 | adipocyte [curation]; extracellular vesicle [curation] | 2018-10-04 |
| Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study | [1]Ian J Neeland, [2]Shruti Singh, [3]Darren K McGuire, [4]Gloria L. Vega, [5]Thomas P Roddy, [6]Dermot F Reilly, [7]Jose Castro-Perez, [8]Julia Kozlitina, [9]Philipp E. Scherer [Full author list] | Diabetologia [curation] | DOI: 10.1007/S00125-018-4720-1
PubMed: 30159588 | ceramides [curation]; insulin resistance [curation]; type 2 diabetes [curation] | 2018-08-29 |
| HDAC11 suppresses the thermogenic program of adipose tissue via BRD2 | [1]Rushita A Bagchi, [2]Bradley S. Ferguson, [3]Matthew S Stratton, [4]Tianjing Hu, [5]Maria A Cavasin, [6]Lei Sun, [7]Ying-Hsi Lin, [8]Dianxin Liu, [9]Pilar Londono, [10]Kunhua Song, [11]Maria F Pino, [12]Lauren M Sparks, [13]Steven R Smith, [14]Philipp E. Scherer, [15]Sheila Collins, [16]Edward Seto, [17]Timothy A McKinsey [Full author list] | JCI insight [curation] | DOI: 10.1172/JCI.INSIGHT.120159
PubMed: 30089714 | | 2018-08-09 |
| Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1 | [1]Fengjiao Sun, [2]Yun Lei, [3]Jingjing You, [4]Chen Li, [5]Linshan Sun, [6]Jacob Garza, [7]Di Zhang, [8]Ming Guo, [9]Philipp E. Scherer, [10]Daniel J Lodge, [11]Xin-Yun Lu [Full author list] | Molecular Psychiatry [curation] | DOI: 10.1038/S41380-018-0102-9
PubMed: 29988086 | | 2018-07-09 |
| Adiponectin Moderates Antidepressant Treatment Outcome in the Combining Medications to Enhance Depression Outcomes Randomized Clinical Trial | [1]Jennifer L Furman, [2]Abigail Soyombo, [3]Andrew H Czysz, [4]Manish K Jha, [5]Thomas J Carmody, [6]Brittany L Mason, [7]Philipp E. Scherer, [8]Madhukar Trivedi [Full author list] | | DOI: 10.1016/J.PMIP.2018.05.001
PubMed: 30859144 | | 2018-06-21 |
| Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation | [1]Qiong A Wang, [2]Anying Song, [3]Wanze Chen, [4]Petra C Schwalie, [5]Fang Zhang, [6]Lavanya Vishvanath, [7]Lei Jiang, [8]Risheng Ye, [9]Mengle Shao, [10]Caroline Tao, [11]Rana K Gupta, [12]Bart Deplancke, [13]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2018.05.022
PubMed: 29909970 | adipocyte [curation] | 2018-06-14 |
| Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction | [1]Victoria H Cruz, [2]Emily N Arner, [3]Katherine W Wynne, [4]Philipp E. Scherer, [5]Rolf Brekken [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2018.06.007
PubMed: 29935921 | | 2018-06-11 |
| Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease. | [1]Lin Jia, [2]Xiuli Chang, [3]Shuwen Qian, [4]Chen Liu, [5]Caleb C Lord, [6]Newaz Ahmed, [7]Charlotte E Lee, [8]Syann Lee, [9]Laurent Gautron, [10]Mack C Mitchell, [11]Jay D Horton, [12]Philipp E. Scherer, [13]Joel K Elmquist [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2018.05.015
PubMed: 29884546 | toll-like receptor [curation] | 2018-05-23 |
| Peroxisome Proliferator-Activated Receptor γ and Its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization | [1]Qiong A Wang, [2]Fang Zhang, [3]Lei Jiang, [4]Risheng Ye, [5]Yu An, [6]Mengle Shao, [7]Caroline Tao, [8]Rana K Gupta, [9]Philipp E. Scherer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00677-17
PubMed: 29483301 | adipocyte [curation] | 2018-04-30 |
| Glucose-regulated protein 78 is essential for cardiac myocyte survival | [1]Xiaoding Wang, [2]Xukun Bi, [3]Guangyu Zhang, [4]Yingfeng Deng, [5]Xiang Luo, [6]Lin Xu, [7]Philipp E. Scherer, [8]Anwarul Ferdous, [9]Guosheng Fu, [10]Thomas G Gillette, [11]Amy S Lee, [12]Xuejun Jiang, [13]Zhao V Wang [Full author list] | Cell Death & Differentiation [curation] | DOI: 10.1038/S41418-018-0109-4
PubMed: 29666470 | | 2018-04-17 |
| Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. | [1]Zhuzhen Zhang, [2]Zhenzhen Zi, [3]Eunice E Lee, [4]Jiawei Zhao, [5]Diana C Contreras, [6]Andrew P South, [7]E. Dale Abel, [8]Benjamin F Chong, [9]Travis Vandergriff, [10]Gregory A Hosler, [11]Philipp E. Scherer, [12]Marcel Mettlen, [13]Jeffrey C Rathmell, [14]Ralph J DeBerardinis, [15]Richard C Wang [Full author list] | Nature Medicine [curation] | DOI: 10.1038/S41591-018-0003-0
PubMed: 29662201 | | 2018-04-16 |
| New zoning laws enforced by glucagon. | [1]Christine M Kusminski, [2]Philipp E. Scherer [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1804203115
PubMed: 29632201 | | 2018-04-09 |
| Adipocyte Xbp1s overexpression drives uridine production and reduces obesity. | [1]Yingfeng Deng, [2]Zhao V Wang, [3]Ruth Gordillo, [4]Yi Zhu, [5]Aktar Ali, [6]Chen Zhang, [7]Xiaoding Wang, [8]Mengle Shao, [9]Zhuzhen Zhang, [10]Puneeth Iyengar, [11]Rana K Gupta, [12]Jay D Horton, [13]Joseph A Hill, [14]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2018.02.013
PubMed: 29551634 | adipocyte [curation]; overexpression [curation] | 2018-03-02 |
| Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. | [1]Risheng Ye, [2]Ruth Gordillo, [3]Mengle Shao, [4]Toshiharu Onodera, [5]Zhe Chen, [6]Shiuhwei Chen, [7]Xiaoli Lin, [8]Jeffrey A SoRelle, [9]Xiaohong Li, [10]Miao Tang, [11]Mark P Keller, [12]Regina Kuliawat, [13]Alan D Attie, [14]Rana K Gupta, [15]William L Holland, [16]Bruce Beutler, [17]Joachim Herz, [18]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI97702
PubMed: 29457786 | obesity [curation] | 2018-02-19 |
| Adipose tissue: The dysfunctional adipocyte - a cancer cell's best friend | [1]Zhuzhen Zhang, [2]Philipp E. Scherer [Full author list] | Nature Reviews Endocrinology [curation] | DOI: 10.1038/NRENDO.2017.174
PubMed: 29302078 | adipocyte [curation] | 2018-01-05 |
| An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents | [1]Fang Zhang, [2]Guiyang Hao, [3]Mengle Shao, [4]Kien Nham, [5]Yu An, [6]Qiong A Wang, [7]Yi Zhu, [8]Christine M Kusminski, [9]Gedaa Hassan, [10]Rana K Gupta, [11]Qiwei Zhai, [12]Xiankai Sun, [13]Philipp E. Scherer, [14]Orhan K Oz [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2017.12.004
PubMed: 29320705 | | 2018-01-01 |
| Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy | [1]Rebecca J Wilson, [2]Joshua C Drake, [3]Di Cui, [4]Mei Zhang, [5]Heather M Perry, [6]Jennifer A Kashatus, [7]Christine M Kusminski, [8]Philipp E. Scherer, [9]David F Kashatus, [10]Mark D. Okusa, [11]Zhen Yan [Full author list] | Mitochondrion [curation] | DOI: 10.1016/J.MITO.2017.12.008
PubMed: 29274400 | | 2017-12-20 |
| Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice | [1]Jonathan Y Xia, [2]Kai Sun, [3]Chelsea Hepler, [4]Alexandra L Ghaben, [5]Rana K Gupta, [6]Yu An, [7]William L Holland, [8]Thomas S Morley, [9]Andrew C Adams, [10]Ruth Gordillo, [11]Christine M Kusminski, [12]Philipp E. Scherer [Full author list] | Diabetologia [curation] | DOI: 10.1007/S00125-017-4516-8
PubMed: 29224189 | | 2017-12-09 |
| Immunologic and endocrine functions of adipose tissue: implications for kidney disease. | [1]Qingzhang Zhu, [2]Philipp E. Scherer [Full author list] | Nature Reviews Nephrology [curation] | DOI: 10.1038/NRNEPH.2017.157
PubMed: 29199276 | | 2017-12-04 |
| Nav1.8 neurons are involved in limiting acute phase responses to dietary fat | [1]Swalpa Udit, [2]Michael Burton, [3]Joseph M. Rutkowski, [4]Syann Lee, [5]Angie L Bookout, [6]Philipp E. Scherer, [7]Joel K Elmquist, [8]Laurent Gautron [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2017.07.012
PubMed: 29031710 | lipid [curation]; fat [curation]; membrane protein [curation]; transport protein [curation]; nerve tissue protein [curation]; Sodium voltage-gated channel alpha subunit 10 [curation]; acute phase reaction [curation]; dietary fats [curation] | 2017-10-01 |
| General theory of skin reinforcement | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0182865
PubMed: 28797059 | | 2017-08-10 |
| MitoNEET-dependent formation of intermitochondrial junctions | [1]Alexandre Vernay, [2]Anna Marchetti, [3]Ayman Sabra, [4]Tania N Jauslin, [5]Manon Rosselin, [6]Philipp E. Scherer, [7]Nicolas Demaurex, [8]Lelio Orci, [9]Pierre Cosson [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1706643114
PubMed: 28716905 | | 2017-07-17 |
| Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations | [1]Maximilian Nitschké, [2]Alexander Bell, [3]Sinem Karaman, [4]Meelad Amouzgar, [5]Joseph M. Rutkowski, [6]Philipp E. Scherer, [7]Kari Alitalo, [8]Donald M McDonald [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2017.05.009
PubMed: 28683257 | | 2017-07-03 |
| Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target | [1]Roberta G Marangoni, [2]Yuri Masui, [3]Feng Fang, [4]Benjamin D Korman, [5]Gabriel Lord, [6]Junghwa Lee, [7]Katja Lakota, [8]Jun Wei, [9]Philipp E. Scherer, [10]Laszlo Otvos, [11]Toshimasa Yamauchi, [12]Naoto Kubota, [13]Takashi Kadowaki, [14]Yoshihide Asano, [15]Shinichi Sato, [16]Warren G Tourtellotte, [17]John Varga [Full author list] | Scientific Reports [curation] | DOI: 10.1038/S41598-017-04162-1
PubMed: 28667272 | | 2017-06-30 |
| Dapagliflozin suppresses glucagon signaling in rodent models of diabetes. | [1]May-Yun Wang, [2]Xinxin Yu, [3]Young Lee, [4]Sara Kay McCorkle, [5]Shiuhwei Chen, [6]Jianping Li, [7]Zhao V Wang, [8]Jaime A Davidson, [9]Philipp E. Scherer, [10]William L Holland, [11]Roger H Unger, [12]Michael G. Roth [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1705845114
PubMed: 28584109 | glucagon [curation] | 2017-06-05 |
| Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Experimental Dermatology [curation] | DOI: 10.1111/EXD.13379
PubMed: 28482134 | adipocyte [curation]; pathophysiology [curation]; androgenic alopecia [curation] | 2017-06-01 |
| Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis | [1]Mathew C Casimiro, [2]Gabriele Di Sante, [3]Agnese Di Rocco, [4]Emanuele Loro, [5]Claudia Pupo, [6]Timothy G Pestell, [7]Sara Bisetto, [8]Marco A. Velasco-Velazquez, [9]Xuanmao Jiao, [10]Zhiping Li, [11]Christine M Kusminski, [12]Erin L Seifert, [13]Chenguang Wang, [14]Daniel Ly, [15]Bin Zheng, [16]Che-Hung Shen, [17]Philipp E. Scherer, [18]Richard Pestell [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-16-0425
PubMed: 28522753 | autophagy [curation] | 2017-05-18 |
| Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice. | [1]Caroline Tao, [2]William L Holland, [3]Qiong A Wang, [4]Mengle Shao, [5]Lin Jia, [6]Kai Sun, [7]Xiaoli Lin, [8]Yi-Chun Kuo, [9]Joshua A Johnson, [10]Ruth Gordillo, [11]Joel K Elmquist, [12]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2017-00024
PubMed: 28323977 | adipocyte [curation]; toll-like receptor [curation]; insulin resistance [curation] | 2017-05-01 |
| Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis | [1]Yu An, [2]Kai Sun, [3]Nolwenn Joffin, [4]Fang Zhang, [5]Yingfeng Deng, [6]Olivier Donzé, [7]Christine M Kusminski, [8]Philipp E. Scherer [Full author list] | eLife [curation] | DOI: 10.7554/ELIFE.24071
PubMed: 28355132 | | 2017-03-29 |
| An adipo-biliary-uridine axis that regulates energy homeostasis. | [1]Yingfeng Deng, [2]Zhao V Wang, [3]Ruth Gordillo, [4]Yu An, [5]Chen Zhang, [6]Qiren Liang, [7]Jun Yoshino, [8]Kelly M Cautivo, [9]Jef K De Brabander, [10]Joel K Elmquist, [11]Jay D Horton, [12]Joseph A. Hill, [13]Samuel Klein, [14]Philipp E. Scherer [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.AAF5375
PubMed: 28302796 | | 2017-03-16 |
| VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements | [1]Jiyoung Park, [2]Min Kim, [3]Kai Sun, [4]Yu An, [5]Xue Gu, [6]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB16-1081
PubMed: 28254844 | | 2017-03-02 |
| Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony | [1]Alexandra L Ghaben, [2]Philipp E. Scherer [Full author list] | Circulation Research [curation] | DOI: 10.1161/CIRCRESAHA.117.310452
PubMed: 28254797 | glucagon [curation] | 2017-03-01 |
| microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism | [1]Sachin Hajarnis, [2]Ronak Lakhia, [3]Matanel Yheskel, [4]Darren Williams, [5]Mehran Sorourian, [6]Xueqing Liu, [7]Karam Aboudehen, [8]Shanrong Zhang, [9]Kara Kersjes, [10]Ryan Galasso, ..., [17]William L Holland, [18]Christine M Kusminski, [19]Philipp E. Scherer, [20]Peter C Harris, [21]Marie Trudel, ... [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS14395
PubMed: 28205547 | mitochondrion [curation]; microRNA [curation]; polycystic kidney disease [curation] | 2017-02-16 |
| Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis | [1]William L Holland, [2]Jonathan Y Xia, [3]Joshua A Johnson, [4]Kai Sun, [5]Mackenzie J Pearson, [6]Ankit X Sharma, [7]Ezekiel Quittner-Strom, [8]Trevor S Tippetts, [9]Ruth Gordillo, [10]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2017.01.002
PubMed: 28271033 | glucose [curation]; overexpression [curation] | 2017-01-12 |
| The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. | [1]Clair Crewe, [2]Yu An, [3]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI88883
PubMed: 28045400 | | 2017-01-03 |
| Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies | [1]Quinn Dufurrena, [2]Farhad M Amjad, [3]Philipp E. Scherer, [4]Louis M Weiss, [5]Jyothi Nagajyothi, [6]Jesse Roth, [7]Herbert B Tanowitz, [8]Regina Kuliawat [Full author list] | Parasitology Research [curation] | DOI: 10.1007/S00436-016-5350-5
PubMed: 28013375 | Trypanosoma cruzi [curation] | 2016-12-24 |
| Adipose Tissue: A Safe Haven for Parasites? | [1]Herbert B Tanowitz, [2]Philipp E. Scherer, [3]Maria M Mota, [4]Luisa M. Figueiredo [Full author list] | Trends in Parasitology [curation] | DOI: 10.1016/J.PT.2016.11.008
PubMed: 28007406 | | 2016-12-19 |
| Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation | [1]Zhigang Lu, [2]Jingjing Xie, [3]Guojin Wu, [4]Jinhui Shen, [5]Robert Collins, [6]Weina Chen, [7]Xunlei Kang, [8]Min Luo, [9]Yizhou Zou, [10]Lily Jun-Shen Huang, [11]James F Amatruda, [12]Tamra Slone, [13]Naomi Winick, [14]Philipp E. Scherer, [15]Cheng Cheng Zhang [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM.4252
PubMed: 27941793 | lymphoblastic leukemia [curation] | 2016-12-12 |
| Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages | [1]Yohei Sanada, [2]Takafumi Yamamoto, [3]Rika Satake, [4]Akiko Yamashita, [5]Sumire Kanai, [6]Norihisa Kato, [7]Fons Aj van de Loo, [8]Fusanori Nishimura, [9]Philipp E. Scherer, [10]Noriyuki Yanaka [Full author list] | Scientific Reports [curation] | DOI: 10.1038/SREP38697
PubMed: 27929048 | adipocyte [curation] | 2016-12-08 |
| Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression. | [1]Joseph M. Rutkowski, [2]Johanne Pastor, [3]Kai Sun, [4]Sun K Park, [5]I Alexandru Bobulescu, [6]Christopher T Chen, [7]Orson W Moe, [8]Philipp E. Scherer [Full author list] | Kidney International [curation] | DOI: 10.1016/J.KINT.2016.09.016
PubMed: 27914707 | | 2016-11-30 |
| SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise | [1]Teppei Fujikawa, [2]Carlos M Castorena, [3]Mackenzie Pearson, [4]Christine M Kusminski, [5]Newaz Ahmed, [6]Pavan K Battiprolu, [7]Ki Woo Kim, [8]Syann Lee, [9]Joseph A Hill, [10]Philipp E. Scherer, [11]William L Holland, [12]Joel K Elmquist [Full author list] | eLife [curation] | DOI: 10.7554/ELIFE.18206
PubMed: 27874828 | | 2016-11-22 |
| Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis. | [1]Jonathan C Jun, [2]Ronald Devera, [3]Dileep C Unnikrishnan, [4]Mi-Kyung Shin, [5]Shannon Bevans-Fonti, [6]Qiaoling Yao, [7]Aman Rathore, [8]Haris Younas, [9]Nils Halberg, [10]Philipp E. Scherer, [11]Vsevolod Y Polotsky [Full author list] | Journal of Molecular Medicine [curation] | DOI: 10.1007/S00109-016-1480-6
PubMed: 27738746 | obesity [curation]; thermogenesis [curation] | 2016-10-14 |
| Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment | [1]Kai Sun, [2]Jiyoung Park, [3]Min Kim, [4]Philipp E. Scherer [Full author list] | Diabetologia [curation] | DOI: 10.1007/S00125-016-4130-1
PubMed: 27717959 | biomarker [curation] | 2016-10-07 |
| Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals | [1]Yi Zhu, [2]Yong Gao, [3]Caroline Tao, [4]Mengle Shao, [5]Shangang Zhao, [6]Wei Huang, [7]Ting Yao, [8]Joshua A Johnson, [9]Tiemin Liu, [10]Aaron M Cypess, ..., [20]Kevin W. Williams, [21]Hua Lin, [22]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2016.08.005
PubMed: 27626200 | Gap junction protein alpha 1 [curation]; Gap junction protein, alpha 1 [curation]; positive regulation of cold-induced thermogenesis [curation] | 2016-09-01 |
| Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons | [1]Jia Sun, [2]Yong Gao, [3]Ting Yao, [4]Yiru Huang, [5]Zhenyan He, [6]Xingxing Kong, [7]Kai-Jiang Yu, [8]Rui-Tao Wang, [9]Hongbo Guo, [10]Jianqun Yan, [11]Yongsheng Chang, [12]Hong Chen, [13]Philipp E. Scherer, [14]Tiemin Liu, [15]Kevin W. Williams [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2016.08.007
PubMed: 27689001 | | 2016-08-18 |
| Adiponectin protects against incident hypertension independent of body fat distribution: observations from the Dallas Heart Study | [1]Poghni A Peri-Okonny, [2]Colby R Ayers, [3]Naim M. Maalouf, [4]Sandeep R Das, [5]James A. de Lemos, [6]Jarett D Berry, [7]Aslan T Turer, [8]Ian J Neeland, [9]Philipp E. Scherer, [10]Wanpen Vongpatanasin [Full author list] | Diabetes - Metabolism: Research and Reviews [curation] | DOI: 10.1002/DMRR.2840
PubMed: 27455039 | | 2016-08-18 |
| Skin aging: are adipocytes the next target? | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Aging [curation] | DOI: 10.18632/AGING.100999
PubMed: 27434510 | cell [curation]; tissue [curation]; adipocyte [curation] | 2016-07-18 |
| Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility | [1]Ingrid Wernstedt Asterholm, [2]Ja Young Kim-Muller, [3]Joseph M. Rutkowski, [4]Clair Crewe, [5]Caroline Tao, [6]Philipp E. Scherer [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2016.04.017
PubMed: 27397737 | glucose intolerance [curation] | 2016-07-07 |
| The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia | [1]Mary E Haas, [2]Amy E Levenson, [3]Xiaowei Sun, [4]Wan-Hui Liao, [5]Joseph M. Rutkowski, [6]Sarah D de Ferranti, [7]Valerie A Schumacher, [8]Philipp E. Scherer, [9]David J Salant, [10]Sudha B Biddinger [Full author list] | Circulation [curation] | DOI: 10.1161/CIRCULATIONAHA.115.020912
PubMed: 27358438 | hypercholesterolemia [curation] | 2016-07-01 |
| Adiponectin: Just Along for the Ride? | [1]Aslan T Turer, [2]Philipp E. Scherer [Full author list] | Circulation Research [curation] | DOI: 10.1161/CIRCRESAHA.116.309226
PubMed: 27458194 | | 2016-07-01 |
| Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis | [1]Yong Hwan Han, [2]Márcio Buffolo, [3]Karla Maria Pires, [4]Shaobo Pei, [5]Philipp E. Scherer, [6]Sihem Boudina [Full author list] | Diabetes [curation] | DOI: 10.2337/DB16-0283
PubMed: 27284109 | adipocyte [curation] | 2016-06-09 |
| Targeting adipose tissue in the treatment of obesity-associated diabetes | [1]Christine M Kusminski, [2]Perry E Bickel, [3]Philipp E. Scherer [Full author list] | Nature Reviews Drug Discovery [curation] | DOI: 10.1038/NRD.2016.75
PubMed: 27256476 | obesity [curation] | 2016-06-03 |
| The Multifaceted Roles of Adipose Tissue-Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture | [1]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB16-0339
PubMed: 27222389 | | 2016-06-01 |
| Are dermal adipocytes involved in psoriasis? | [1]Ilja L Kruglikov, [2]Philipp E. Scherer, [3]Uwe Wollina [Full author list] | Experimental Dermatology [curation] | DOI: 10.1111/EXD.12996
PubMed: 26913468 | adipocyte [curation] | 2016-05-18 |
| Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges | [1]Risheng Ye, [2]Miao Wang, [3]Qiong A Wang, [4]Stephen B Spurgin, [5]Zhao V Wang, [6]Kai Sun, [7]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2016.05.001
PubMed: 27408770 | | 2016-05-10 |
| Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk | [1]Jennifer H Stern, [2]Joseph M. Rutkowski, [3]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2016.04.011
PubMed: 27166942 | fatty acid [curation] | 2016-05-01 |
| Obesity, Diabetes, and Cardiovascular Diseases: A Compendium | [1]Philipp E. Scherer, [2]Joseph A Hill [Full author list] | Circulation Research [curation] | DOI: 10.1161/CIRCRESAHA.116.308999
PubMed: 27230636 | obesity [curation]; cardiovascular disease [curation] | 2016-05-01 |
| Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements? | [1]Qiong A Wang, [2]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/J.TEM.2016.03.008
PubMed: 27040112 | adipocyte [curation] | 2016-03-31 |
| Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance | [1]Chong Yew Tan, [2]Samuel Virtue, [3]Steven Murfitt, [4]Lee D. Roberts, [5]Yi Hui Phua, [6]Martin Dale, [7]Julian L Griffin, [8]Francisco Tinahones, [9]Philipp E. Scherer, [10]Antonio Vidal-Puig [Full author list] | Scientific Reports [curation] | DOI: 10.1038/SREP23873
PubMed: 27027977 | obesity [curation]; fatty acid [curation]; insulin resistance [curation]; Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance [curation] | 2016-03-30 |
| Adiponectin, the past two decades | [1]Zhao V Wang, [2]Philipp E. Scherer [Full author list] | Journal of Molecular Cell Biology [curation] | DOI: 10.1093/JMCB/MJW011
PubMed: 26993047 | | 2016-03-18 |
| Fibrosis-streaks and splatters: Some things are not always what they seem to be | [1]Ingrid Wernstedt Asterholm, [2]Philipp E. Scherer [Full author list] | Obesity [curation] | DOI: 10.1002/OBY.21430
PubMed: 26916237 | | 2016-03-01 |
| Obesity: Slim without the gym--the magic of chilling out | [1]Puneeth Iyengar, [2]Philipp E. Scherer [Full author list] | Nature Reviews Endocrinology [curation] | DOI: 10.1038/NRENDO.2016.20
PubMed: 26915527 | | 2016-02-26 |
| MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk | [1]Christine M Kusminski, [2]Shiuhwei Chen, [3]Risheng Ye, [4]Kai Sun, [5]Qiong A Wang, [6]Stephen B Spurgin, [7]Phillip E Sanders, [8]Joseph T Brozinick, [9]Werner J Geldenhuys, [10]Wen-Hong Li, [11]Roger H Unger, [12]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB15-1323
PubMed: 26895793 | | 2016-02-19 |
| Elevated adiponectin prevents HIV protease inhibitor toxicity and preserves cerebrovascular homeostasis in mice | [1]Kalavathi Dasuri, [2]Jennifer K Pepping, [3]Sun-Ok Fernandez-Kim, [4]Sunita Gupta, [5]Jeffrey Keller, [6]Philipp E. Scherer, [7]Annadora J Bruce-Keller [Full author list] | Biochimica et Biophysica Acta [curation] | DOI: 10.1016/J.BBADIS.2016.02.009
PubMed: 26912411 | HIV [curation] | 2016-02-18 |
| Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion | [1]Ozlem Senol-Cosar, [2]Rachel J Roth Flach, [3]Marina DiStefano, [4]Anil Chawla, [5]Sarah Nicoloro, [6]Juerg Straubhaar, [7]Olga T Hardy, [8]Hye Lim Noh, [9]Jason K Kim, [10]Martin Wabitsch, [11]Philipp E. Scherer, [12]Michael P Czech [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS10686
PubMed: 26880110 | adipocyte [curation] | 2016-02-16 |
| Glucagon therapeutics: Dawn of a new era for diabetes care | [1]Jaime A Davidson, [2]William L Holland, [3]Michael G. Roth, [4]May-Yun Wang, [5]Young Lee, [6]Xinxin Yu, [7]Sara K McCorkle, [8]Philipp E. Scherer, [9]Roger H Unger [Full author list] | Diabetes - Metabolism: Research and Reviews [curation] | DOI: 10.1002/DMRR.2773
PubMed: 26729301 | glucagon [curation] | 2016-02-07 |
| Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier | [1]Yi Zhu, [2]Clair Crewe, [3]Philipp E. Scherer [Full author list] | Science Translational Medicine [curation] | DOI: 10.1126/SCITRANSLMED.AAD6793
PubMed: 26819194 | | 2016-01-27 |
| Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot? | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Experimental Dermatology [curation] | DOI: 10.1111/EXD.12941
PubMed: 26781768 | adipocyte [curation] | 2016-01-19 |
| Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue | [1]María Valero-Muñoz, [2]Shanpeng Li, [3]Richard M Wilson, [4]Maarten Hulsmans, [5]Tamar Aprahamian, [6]José J Fuster, [7]Matthias Nahrendorf, [8]Philipp E. Scherer, [9]Flora Sam [Full author list] | Circulation: Heart Failure [curation] | DOI: 10.1161/CIRCHEARTFAILURE.115.002724
PubMed: 26721917 | ejection fraction [curation]; Heart failure with preserved ejection fraction [curation] | 2016-01-01 |
| A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents | [1]Romy Kursawe, [2]Vishwa D Dixit, [3]Philipp E. Scherer, [4]Nicola Santoro, [5]Deepak Narayan, [6]Ruth Gordillo, [7]Cosimo Giannini, [8]Ximena Lopez, [9]Bridget Pierpont, [10]Jessica Nouws, [11]Gerald I. Shulman, [12]Sonia Caprio [Full author list] | Diabetes [curation] | DOI: 10.2337/DB15-1478
PubMed: 26718495 | obesity [curation]; inflammasome complex [curation] | 2015-12-30 |
| Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance | [1]Chong Yew Tan, [2]Samuel Virtue, [3]Steven Murfitt, [4]Lee D. Roberts, [5]Yi Hui Phua, [6]Martin Dale, [7]Julian L Griffin, [8]Francisco Tinahones, [9]Philipp E. Scherer, [10]Antonio Vidal-Puig [Full author list] | Scientific Reports [curation] | DOI: 10.1038/SREP18366
PubMed: 26679101 | obesity [curation]; fatty acid [curation]; insulin resistance [curation] | 2015-12-17 |
| Dermal Adipocytes: From Irrelevance to Metabolic Targets? | [1]Ilja L Kruglikov, [2]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/J.TEM.2015.11.002
PubMed: 26643658 | adipocyte [curation] | 2015-11-28 |
| Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase | [1]Risheng Ye, [2]Qiong A Wang, [3]Caroline Tao, [4]Lavanya Vishvanath, [5]Mengle Shao, [6]Jeffery G McDonald, [7]Rana K Gupta, [8]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2015.08.004
PubMed: 26629402 | adipocyte [curation]; tamoxifen [curation]; adipogenesis [curation] | 2015-08-29 |
| Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation | [1]Qiong A Wang, [2]Caroline Tao, [3]Lei Jiang, [4]Mengle Shao, [5]Risheng Ye, [6]Yi Zhu, [7]Ruth Gordillo, [8]Aktar Ali, [9]Yun Lian, [10]William L Holland, [11]Rana K Gupta, [12]Philipp E. Scherer [Full author list] | Nature Cell Biology [curation] | DOI: 10.1038/NCB3217
PubMed: 26280538 | adipocyte [curation] | 2015-08-17 |
| Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements | [1]Thomas S Morley, [2]Jonathan Y Xia, [3]Philipp E. Scherer [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS8906
PubMed: 26243466 | adipocyte [curation]; preproinsulin [curation] | 2015-08-05 |
| Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice | [1]Kirsten P Stone, [2]Desiree Wanders, [3]Lucie F Calderon, [4]Stephen B Spurgin, [5]Philipp E. Scherer, [6]Thomas W Gettys [Full author list] | Obesity [curation] | DOI: 10.1002/OBY.21177
PubMed: 26237535 | | 2015-08-03 |
| E4orf1 induction in adipose tissue promotes insulin-independent signaling in the adipocyte | [1]Christine M Kusminski, [2]Violeta I Gallardo-Montejano, [3]Zhao V Wang, [4]Vijay Hegde, [5]Perry E Bickel, [6]Nikhil V Dhurandhar, [7]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2015.07.004
PubMed: 26500839 | adipocyte [curation] | 2015-07-26 |
| Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis | [1]Jonathan Y Xia, [2]William L Holland, [3]Christine M Kusminski, [4]Kai Sun, [5]Ankit X Sharma, [6]Mackenzie J Pearson, [7]Angelika J Sifuentes, [8]Jeffrey G McDonald, [9]Ruth Gordillo, [10]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2015.06.007
PubMed: 26190650 | ceramides [curation]; steatosis [curation] | 2015-07-16 |
| Circulating Adipokines and Inflammatory Markers and Postmenopausal Breast Cancer Risk | [1]Marc J Gunter, [2]Tao Wang, [3]Mary Cushman, [4]Xiaonan Xue, [5]Sylvia Wassertheil-Smoller, [6]Howard D Strickler, [7]Thomas E Rohan, [8]JoAnn E. Manson, [9]Anne McTiernan, [10]Robert C Kaplan, [11]Philipp E. Scherer, [12]Rowan T Chlebowski, [13]Linda G Snetselaar, [14]Dan Wang, [15]Gloria Y F Ho [Full author list] | Journal of the National Cancer Institute [curation] | DOI: 10.1093/JNCI/DJV169
PubMed: 26185195 | inflammation [curation] | 2015-07-16 |
| A Prospective Analysis of Plasma Adiponectin and Risk of Incident Cancer: The Dallas Heart Study | [1]Muhammad Shaalan Beg, [2]Sadia Saleem, [3]Aslan Turer, [4]Colby R Ayers, [5]James A. de Lemos, [6]Amit Khera, [7]Philipp E. Scherer, [8]Susan G Lakoski [Full author list] | Journal of the National Comprehensive Cancer Network [curation] | DOI: 10.6004/JNCCN.2015.0104
PubMed: 26150581 | | 2015-07-01 |
| Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome | [1]Jeremy T Warshauer, [2]Ximena Lopez, [3]Ruth Gordillo, [4]Jessica Hicks, [5]William L Holland, [6]Estelle Anuwe, [7]Martin B Blankfard, [8]Philipp E. Scherer, [9]Ildiko Lingvay [Full author list] | Diabetes - Metabolism: Research and Reviews [curation] | DOI: 10.1002/DMRR.2662
PubMed: 25959529 | ceramides [curation]; metabolic syndrome [curation] | 2015-06-17 |
| Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure | [1]Virginie Mansuy-Aubert, [2]Laurent Gautron, [3]Syann Lee, [4]Angie L Bookout, [5]Christine M Kusminski, [6]Kai Sun, [7]Yuan Zhang, [8]Philipp E. Scherer, [9]David Mangelsdorf, [10]Joel K Elmquist [Full author list] | eLife [curation] | DOI: 10.7554/ELIFE.06667
PubMed: 26076474 | | 2015-06-15 |
| Adiponectin-SOGA Dissociation in Type 1 Diabetes | [1]Terry P Combs, [2]Janet K Snell-Bergeon, [3]David M Maahs, [4]Bryan C Bergman, [5]Marie Lamarche, [6]Laura Iberkleid, [7]Omar AbdelBaky, [8]Roland Tisch, [9]Philipp E. Scherer, [10]Errol B Marliss [Full author list] | The Journal of Clinical Endocrinology and Metabolism [curation] | DOI: 10.1210/JC.2015-1275
PubMed: 26052615 | type-1 diabetes [curation] | 2015-06-08 |
| Leptin beyond the lipostat: key component of blood pressure regulation | [1]Christine M Kusminski, [2]Philipp E. Scherer [Full author list] | Circulation Research [curation] | DOI: 10.1161/CIRCRESAHA.115.305937
PubMed: 25858061 | | 2015-04-01 |
| Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors | [1]Roberta Goncalves Marangoni, [2]Benjamin D Korman, [3]Jun Wei, [4]Tammara A Wood, [5]Lauren V Graham, [6]Michael L Whitfield, [7]Philipp E. Scherer, [8]Warren G Tourtellotte, [9]John Varga [Full author list] | Arthritis & Rheumatology [curation] | DOI: 10.1002/ART.38990
PubMed: 25504959 | | 2015-04-01 |
| Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets | [1]Risheng Ye, [2]Miao Wang, [3]Qiong A Wang, [4]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2015-1066
PubMed: 25815422 | | 2015-03-27 |
| The cell biology of fat expansion | [1]Joseph M. Rutkowski, [2]Jennifer H Stern, [3]Philipp E. Scherer [Full author list] | Journal of Cell Biology [curation] | DOI: 10.1083/JCB.201409063
PubMed: 25733711 | cell biology [curation]; cell [curation]; obesity [curation]; tissue [curation]; energy metabolism [curation]; physiological phenomenon [curation] | 2015-03-02 |
| Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes | [1]Joel S Burrill, [2]Eric K Long, [3]Brian Reilly, [4]Yingfeng Deng, [5]Ian M Armitage, [6]Philipp E. Scherer, [7]David A Bernlohr [Full author list] | Molecular Endocrinology [curation] | DOI: 10.1210/ME.2014-1275
PubMed: 25635940 | adipocyte [curation] | 2015-01-30 |
| Maternal adiponectin controls milk composition to prevent neonatal inflammation | [1]Zixue Jin, [2]Yang Du, [3]Adam G Schwaid, [4]Ingrid W Asterholm, [5]Philipp E. Scherer, [6]Alan Saghatelian, [7]Yihong Wan [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2014-1738
PubMed: 25590242 | | 2015-01-15 |
| Adipose tissue biology in 2014: Advances in our understanding of adipose tissue homeostasis | [1]Jennifer H Stern, [2]Philipp E. Scherer [Full author list] | Nature Reviews Endocrinology [curation] | DOI: 10.1038/NRENDO.2014.219
PubMed: 25511312 | tissue homeostasis [curation] | 2014-12-16 |
| MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver | [1]Kedryn K Baskin, [2]Chad E Grueter, [3]Christine M Kusminski, [4]William L Holland, [5]Angie L Bookout, [6]Santosh Satapati, [7]Y Megan Kong, [8]Shawn C Burgess, [9]Craig R Malloy, [10]Philipp E. Scherer, [11]Christopher B Newgard, [12]Rhonda Bassel-Duby, [13]Eric N Olson [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.15252/EMMM.201404218
PubMed: 25422356 | | 2014-11-24 |
| Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling | [1]Sophie de Seigneux, [2]Marie Courbebaisse, [3]Joseph M. Rutkowski, [4]Alexandra Wilhelm-Bals, [5]Marie Metzger, [6]Stellor Nlandu Khodo, [7]Udo Hasler, [8]Hassib Chehade, [9]Eva Dizin, [10]Arezoo Daryadel, [11]Benedicte Stengel, [12]NephroTest Study Group, [13]E Girardin, [14]Dominique Prié, [15]Carsten A Wagner, [16]Philipp E. Scherer, [17]Pierre-Yves Martin, [18]Pascal Houillier, [19]Eric Feraille [Full author list] | Journal of the American Society of Nephrology [curation] | DOI: 10.1681/ASN.2014010104
PubMed: 25349200 | | 2014-10-27 |
| Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration | [1]Risheng Ye, [2]William L Holland, [3]Ruth Gordillo, [4]Miao Wang, [5]Qiong A Wang, [6]Mengle Shao, [7]Thomas S Morley, [8]Rana K Gupta, [9]Andreas Stahl, [10]Philipp E. Scherer [Full author list] | eLife [curation] | DOI: 10.7554/ELIFE.03851
PubMed: 25339419 | preproinsulin [curation] | 2014-10-23 |
| High fat diet modulates Trypanosoma cruzi infection associated myocarditis | [1]Fnu Nagajyothi, [2]Louis M Weiss, [3]Dazhi Zhao, [4]Wade Koba, [5]Linda A Jelicks, [6]Min-Hui Cui, [7]Stephen M Factor, [8]Philipp E. Scherer, [9]Herbert B Tanowitz [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0003118
PubMed: 25275627 | Trypanosoma cruzi [curation] | 2014-10-02 |
| Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells | [1]Young Lee, [2]Eric D Berglund, [3]Xinxin Yu, [4]May-Yun Wang, [5]Matthew R Evans, [6]Philipp E. Scherer, [7]William L Holland, [8]Maureen J Charron, [9]Michael G Roth, [10]Roger H Unger [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1409638111
PubMed: 25157166 | hyperglycemia [curation]; insulin resistance [curation]; type 2 diabetes [curation]; preproinsulin [curation] | 2014-08-25 |
| Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction | [1]Komei Tanaka, [2]Richard M Wilson, [3]Eric E Essick, [4]Jennifer L Duffen, [5]Philipp E. Scherer, [6]Noriyuki Ouchi, [7]Flora Sam [Full author list] | Circulation: Heart Failure [curation] | DOI: 10.1161/CIRCHEARTFAILURE.114.001279
PubMed: 25149095 | heart failure [curation]; ejection fraction [curation]; Heart failure with preserved ejection fraction [curation] | 2014-08-22 |
| Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease | [1]Shoshana Burke, [2]Fnu Nagajyothi, [3]Mia M Thi, [4]Menachem Hanani, [5]Philipp E. Scherer, [6]Herbert B Tanowitz, [7]David C Spray [Full author list] | Microbes and Infection [curation] | DOI: 10.1016/J.MICINF.2014.08.006
PubMed: 25150689 | adipocyte [curation]; Chagas disease [curation] | 2014-08-21 |
| Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis | [1]Kevin W. Williams, [2]Tiemin Liu, [3]Xingxing Kong, [4]Makoto Fukuda, [5]Yingfeng Deng, [6]Eric D Berglund, [7]Zhuo Deng, [8]Yong Gao, [9]Tianya Liu, [10]Jong-Woo Sohn, [11]Lin Jia, [12]Teppei Fujikawa, [13]Daisuke Kohno, [14]Michael M Scott, [15]Syann Lee, [16]Charlotte E Lee, [17]Kai Sun, [18]Yongsheng Chang, [19]Philipp E. Scherer, [20]Joel K Elmquist [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2014.06.002
PubMed: 25017942 | | 2014-07-10 |
| Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection | [1]Jian-Jun Wen, [2]Fnu Nagajyothi, [3]Fabiana S Machado, [4]Louis M Weiss, [5]Philipp E. Scherer, [6]Herbert B Tanowitz, [7]Nisha Jain Garg [Full author list] | Parasitology Research [curation] | DOI: 10.1007/S00436-014-3977-7
PubMed: 24948102 | Trypanosoma cruzi [curation] | 2014-06-20 |
| Obesity and cancer--mechanisms underlying tumour progression and recurrence | [1]Jiyoung Park, [2]Thomas S Morley, [3]Min Kim, [4]Deborah J. Clegg, [5]Philipp E. Scherer [Full author list] | Nature Reviews Endocrinology [curation] | DOI: 10.1038/NRENDO.2014.94
PubMed: 24935119 | obesity [curation]; tumor progression [curation] | 2014-06-17 |
| Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling | [1]Ingrid Wernstedt Asterholm, [2]Caroline Tao, [3]Thomas S Morley, [4]Qiong A Wang, [5]Fernando Delgado-Lopez, [6]Zhao V Wang, [7]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2014.05.005
PubMed: 24930973 | adipocyte [curation] | 2014-06-12 |
| Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia | [1]Eric D Berglund, [2]Tiemin Liu, [3]Xingxing Kong, [4]Jong-Woo Sohn, [5]Linh Vong, [6]Zhuo Deng, [7]Charlotte E Lee, [8]Syann Lee, [9]Kevin W. Williams, [10]David P Olson, [11]Philipp E. Scherer, [12]Bradford B Lowell, [13]Joel K Elmquist [Full author list] | Nature Neuroscience [curation] | DOI: 10.1038/NN.3737
PubMed: 24908101 | thermogenesis [curation] | 2014-06-08 |
| ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue | [1]Min Kim, [2]Michael D Neinast, [3]Aaron P Frank, [4]Kai Sun, [5]Jiyoung Park, [6]Jordan A Zehr, [7]Lavanya Vishvanath, [8]Eugenia Morselli, [9]Mason Amelotte, [10]Biff F. Palmer, [11]Rana K Gupta, [12]Philipp E. Scherer, [13]Deborah J. Clegg [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2014.05.007
PubMed: 25161887 | | 2014-06-07 |
| MitoNEET-mediated effects on browning of white adipose tissue | [1]Christine M Kusminski, [2]Jiyoung Park, [3]Philipp E. Scherer [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS4962
PubMed: 24865177 | | 2014-05-28 |
| Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance | [1]Lin Jia, [2]Claudia R Vianna, [3]Makoto Fukuda, [4]Eric D Berglund, [5]Chen Liu, [6]Caroline Tao, [7]Kai Sun, [8]Tiemin Liu, [9]Matthew Harper, [10]Charlotte E Lee, [11]Syann Lee, [12]Philipp E. Scherer, [13]Joel K Elmquist [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS4878
PubMed: 24815961 | obesity [curation]; toll-like receptor [curation]; insulin resistance [curation]; preproinsulin [curation] | 2014-05-12 |
| Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1. | [1]Dorothy I Mundy, [2]Adam M Lopez, [3]Kenneth S Posey, [4]Jen-Chieh Chuang, [5]Charina M Ramirez, [6]Philipp E. Scherer, [7]Stephen D Turley [Full author list] | Biochimica et Biophysica Acta [curation] | DOI: 10.1016/J.BBALIP.2014.04.002
PubMed: 24747682 | | 2014-04-18 |
| Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1 | [1]Meilian Liu, [2]Juli Bai, [3]Sijia He, [4]Ricardo Villarreal, [5]Derong Hu, [6]Chuntao Zhang, [7]Xin Yang, [8]Huiyun Liang, [9]Thomas J Slaga, [10]Yonghao Yu, [11]Zhiguang Zhou, [12]John Blenis, [13]Philipp E. Scherer, [14]Lily Q Dong, [15]Feng Liu [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2014.03.018
PubMed: 24746805 | phosphorylation [curation]; thermogenesis [curation]; Growth factor receptor bound protein 10 [curation]; Growth factor receptor bound protein 10 [curation]; positive regulation of cold-induced thermogenesis [curation] | 2014-04-17 |
| Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure | [1]Kai Sun, [2]Christine M Kusminski, [3]Kate Luby-Phelps, [4]Stephen B Spurgin, [5]Yu An, [6]Qiong A Wang, [7]William L Holland, [8]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2014.03.010
PubMed: 24944907 | cold hardiness [curation] | 2014-04-05 |
| Fabp4, a new player in the adipo-pancreatic axis | [1]Risheng Ye, [2]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2014.03.009
PubMed: 24944893 | | 2014-04-03 |
| PPARγ in vagal neurons regulates high-fat diet induced thermogenesis | [1]Chen Liu, [2]Angie L Bookout, [3]Syann Lee, [4]Kai Sun, [5]Lin Jia, [6]Charlotte Lee, [7]Swalpa Udit, [8]Yingfeng Deng, [9]Philipp E. Scherer, [10]David Mangelsdorf, [11]Laurent Gautron, [12]Joel K Elmquist [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2014.01.021
PubMed: 24703703 | thermogenesis [curation]; Peroxisome proliferator activated receptor gamma [curation] | 2014-04-01 |
| Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction | [1]Kai Sun, [2]Jiyoung Park, [3]Olga T Gupta, [4]William L Holland, [5]Pernille Auerbach, [6]Ningyan Zhang, [7]Roberta Goncalves Marangoni, [8]Sarah M Nicoloro, [9]Michael P Czech, [10]John Varga, [11]Thorkil Ploug, [12]Zhiqiang An, [13]Philipp E. Scherer [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS4485
PubMed: 24647224 | | 2014-03-19 |
| Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice | [1]Ingrid W Asterholm, [2]Joseph M. Rutkowski, [3]Teppei Fujikawa, [4]You-Ree Cho, [5]Makoto Fukuda, [6]Caroline Tao, [7]Zhao V Wang, [8]Rana K Gupta, [9]Joel K Elmquist, [10]Philipp E. Scherer [Full author list] | Diabetologia [curation] | DOI: 10.1007/S00125-014-3210-3
PubMed: 24623101 | atherosclerosis [curation] | 2014-03-13 |
| Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway | [1]Zhao V Wang, [2]Yingfeng Deng, [3]Ningguo Gao, [4]Zully Pedrozo, [5]Dan L Li, [6]Cyndi R Morales, [7]Alfredo Criollo, [8]Xiang Luo, [9]Wei Tan, [10]Nan Jiang, [11]Mark A Lehrman, [12]Beverly A Rothermel, [13]Ann-Hwee Lee, [14]Sergio Lavandero, [15]Pradeep P A Mammen, [16]Anwarul Ferdous, [17]Thomas G Gillette, [18]Philipp E. Scherer, [19]Joseph A Hill [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2014.01.014
PubMed: 24630721 | | 2014-03-01 |
| Differential transendothelial transport of adiponectin complexes | [1]Joseph M. Rutkowski, [2]Nils Halberg, [3]Qiong A Wang, [4]William L Holland, [5]Jonathan Y Xia, [6]Philipp E. Scherer [Full author list] | Cardiovascular Diabetology [curation] | DOI: 10.1186/1475-2840-13-47
PubMed: 24552349 | | 2014-02-20 |
| Improved methodologies for the study of adipose biology: insights gained and opportunities ahead | [1]Qiong A Wang, [2]Philipp E. Scherer, [3]Rana K Gupta [Full author list] | Journal of Lipid Research [curation] | DOI: 10.1194/JLR.R046441
PubMed: 24532650 | | 2014-02-16 |
| A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome | [1]Ana Carolina Bueno, [2]Kai Sun, [3]Clarissa Silva Martins, [4]Jorge Elias Junior, [5]Wallace Miranda, [6]Caroline Tao, [7]Maria C Foss-Freitas, [8]Marco Antonio Barbieri, [9]Heloísa Bettiol, [10]Margaret de Castro, [11]Philipp E. Scherer, [12]Sonir R Antonini [Full author list] | The Journal of Clinical Endocrinology and Metabolism [curation] | DOI: 10.1210/JC.2013-3009
PubMed: 24432991 | metabolic syndrome [curation] | 2014-01-16 |
| Role of extracellular signal-regulated kinase 5 in adipocyte signaling | [1]Hong Zhu, [2]Sara Guariglia, [3]Wenjing Li, [4]Deborah Brancho, [5]Zhao V Wang, [6]Philipp E. Scherer, [7]Chi-Wing Chow [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M113.506584
PubMed: 24425864 | adipocyte [curation] | 2014-01-14 |
| The AdipoChaser mouse: A model tracking adipogenesis in vivo | [1]Qiong A Wang, [2]Philipp E. Scherer [Full author list] | Adipocyte [curation] | DOI: 10.4161/ADIP.27656
PubMed: 24719789 | adipogenesis [curation] | 2014-01-14 |
| Ceramides and cardiac function in children with chronic kidney disease | [1]Mark Mitsnefes, [2]Philipp E. Scherer, [3]Lisa Aronson Friedman, [4]Ruth Gordillo, [5]Susan L Furth, [6]Bradley A Warady, [7]CKiD study group [Full author list] | Pediatric Nephrology [curation] | DOI: 10.1007/S00467-013-2642-1
PubMed: 24389650 | ceramides [curation] | 2014-01-05 |
| The adipokine/ceramide axis: key aspects of insulin sensitization | [1]Jonathan Y. Xia, [2]Thomas S. Morley, [3]Philipp E. Scherer [Full author list] | Biochimie [curation] | DOI: 10.1016/J.BIOCHI.2013.08.013
PubMed: 23969158 | preproinsulin [curation] | 2014-01-01 |
| Isolation and quantitation of adiponectin higher order complexes | [1]Joseph M. Rutkowski, [2]Philipp E. Scherer [Full author list] | Methods in Enzymology [curation] | DOI: 10.1016/B978-0-12-411619-1.00013-6
PubMed: 24480350 | | 2014-01-01 |
| Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket | [1]Shih-Chia Tso, [2]Xiangbing Qi, [3]Wen-Jun Gui, [4]Cheng-Yang Wu, [5]Jacinta L Chuang, [6]Ingrid Wernstedt Asterholm, [7]Lorraine K Morlock, [8]Kyle Owens, [9]Philipp E. Scherer, [10]Noelle S Williams, [11]Uttam K Tambar, [12]Richard M Wynn, [13]David T Chuang [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M113.533885
PubMed: 24356970 | cell biology [curation]; binding pocket [curation] | 2013-12-19 |
| Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity | [1]Denise E Lackey, [2]David H Burk, [3]Mohamed R Ali, [4]Rouzbeh Mostaedi, [5]William H Smith, [6]Jiyoung Park, [7]Philipp E. Scherer, [8]Shundra A Seay, [9]Colin S McCoin, [10]Paolo Bonaldo, [11]Sean H Adams [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00476.2013
PubMed: 24302007 | obesity [curation] | 2013-12-03 |
| Cell Biology. Ronning after the adiponectin receptors | [1]William L Holland, [2]Philipp E. Scherer [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.1249077
PubMed: 24357309 | cell biology [curation] | 2013-12-01 |
| Intermittent hypoxia exacerbates pancreatic β-cell dysfunction in a mouse model of diabetes mellitus | [1]Shariq I Sherwani, [2]Carolyn Aldana, [3]Saif Usmani, [4]Christopher Adin, [5]Sainath Kotha, [6]Mahmood Khan, [7]Timothy Eubank, [8]Philipp E. Scherer, [9]Narasimham Parinandi, [10]Ulysses J Magalang [Full author list] | Sleep [curation] | DOI: 10.5665/SLEEP.3214
PubMed: 24293759 | hypoxia [curation] | 2013-12-01 |
| Adiponectin: basic and clinical aspects. Preface | [1]Philipp E. Scherer [Full author list] | Best Practice and Research: Clinical Endocrinology and Metabolism [curation] | DOI: 10.1016/J.BEEM.2013.11.004
PubMed: 24417940 | | 2013-11-21 |
| Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine | [1]Roger H Unger, [2]Philipp E. Scherer, [3]William L Holland [Full author list] | Molecular Biology of the Cell [curation] | DOI: 10.1091/MBC.E12-10-0774
PubMed: 24072813 | | 2013-10-01 |
| Tracking adipogenesis during white adipose tissue development, expansion and regeneration | [1]Qiong A Wang, [2]Caroline Tao, [3]Rana K Gupta, [4]Philipp E. Scherer [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM.3324
PubMed: 23995282 | adipogenesis [curation] | 2013-09-01 |
| Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism | [1]Congcong He, [2]Yongjie Wei, [3]Kai Sun, [4]Binghua Li, [5]Xiaonan Dong, [6]Zhongju Zou, [7]Yang Liu, [8]Lisa N Kinch, [9]Shaheen Khan, [10]Sangita Sinha, [11]Ramnik J Xavier, [12]Nick Grishin, [13]Guanghua Xiao, [14]Eeva-Liisa Eskelinen, [15]Philipp E. Scherer, [16]Jennifer L Whistler, [17]Beth Levine [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2013.07.035
PubMed: 23954414 | G protein-coupled receptor [curation]; autophagy [curation]; G protein-coupled receptor catabolic process [curation]; G protein-coupled receptor associated sorting protein 1 [curation]; Beclin 2 [curation]; G protein-coupled receptor associated sorting protein 1 [curation]; Cannabinoid receptor 1 (brain) [curation]; Beclin 2 [curation] | 2013-08-29 |
| Fibrosis and adipose tissue dysfunction | [1]Kai Sun, [2]Joan Tordjman, [3]Karine Clément, [4]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2013.06.016
PubMed: 23954640 | | 2013-08-15 |
| Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis | [1]Antonio Giordano, [2]Incoronata Murano, [3]Eleonora Mondini, [4]Jessica Perugini, [5]Arianna Smorlesi, [6]Ilenia Severi, [7]Rocco Barazzoni, [8]Philipp E. Scherer, [9]Saverio Cinti [Full author list] | Journal of Lipid Research [curation] | DOI: 10.1194/JLR.M038638
PubMed: 23836106 | obesity [curation]; adipocyte [curation] | 2013-07-08 |
| Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. | [1]Luciano F Drager, [2]Qiaoling Yao, [3]Karen L Hernandez, [4]Mi-Kyung Shin, [5]Shannon Bevans-Fonti, [6]Jason Gay, [7]Thomas E Sussan, [8]Jonathan C Jun, [9]Allen C Myers, [10]Gunilla Olivecrona, [11]Alan R Schwartz, [12]Nils Halberg, [13]Philipp E. Scherer, [14]Gregg L. Semenza, [15]David R Powell, [16]Vsevolod Y Polotsky [Full author list] | American Journal of Respiratory and Critical Care Medicine [curation] | DOI: 10.1164/RCCM.201209-1688OC
PubMed: 23328524 | hypoxia [curation]; atherosclerosis [curation] | 2013-07-01 |
| Adipocytes: impact on tumor growth and potential sites for therapeutic intervention | [1]Simona Hefetz-Sela, [2]Philipp E. Scherer [Full author list] | Pharmacology & Therapeutics [curation] | DOI: 10.1016/J.PHARMTHERA.2013.01.008
PubMed: 23353703 | adipocyte [curation] | 2013-05-01 |
| An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice | [1]William L Holland, [2]Andrew C Adams, [3]Joseph T Brozinick, [4]Hai H Bui, [5]Yukiko Miyauchi, [6]Christine M Kusminski, [7]Steven M Bauer, [8]Mark Wade, [9]Esha Singhal, [10]Christine C Cheng, [11]Katherine Volk, [12]Ming-Shang Kuo, [13]Ruth Gordillo, [14]Alexei Kharitonenkov, [15]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2013.03.019
PubMed: 23663742 | ceramides [curation]; preproinsulin [curation] | 2013-05-01 |
| Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours | [1]Jiyoung Park, [2]Thomas S Morley, [3]Philipp E. Scherer [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.1002/EMMM.201202006
PubMed: 23629957 | cisplatin [curation] | 2013-04-30 |
| Adiponectin, driver or passenger on the road to insulin sensitivity? | [1]Risheng Ye, [2]Philipp E. Scherer [Full author list] | Molecular Metabolism [curation] | DOI: 10.1016/J.MOLMET.2013.04.001
PubMed: 24049728 | preproinsulin [curation] | 2013-04-19 |
| Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women | [1]Rachel P. Wildman, [2]Dan Wang, [3]Ivonne Fernandez, [4]Peter Mancuso, [5]Nanette Santoro, [6]Philipp E. Scherer, [7]Mary Frances Roy Sowers [Full author list] | Obesity [curation] | DOI: 10.1002/OBY.20256
PubMed: 23592672 | testosterone [curation] | 2013-03-01 |
| Adiponectin promotes functional recovery after podocyte ablation | [1]Joseph M. Rutkowski, [2]Zhao V Wang, [3]Ae Seo Deok Park, [4]Jianning Zhang, [5]Dihua Zhang, [6]Ming Chang Hu, [7]Orson W Moe, [8]Katalin Susztak, [9]Philipp E. Scherer [Full author list] | Journal of the American Society of Nephrology [curation] | DOI: 10.1681/ASN.2012040414
PubMed: 23334396 | | 2013-01-18 |
| Alterations in glucose homeostasis in a murine model of Chagas disease | [1]Fnu Nagajyothi, [2]Regina Kuliawat, [3]Christine M Kusminski, [4]Fabiana S Machado, [5]Mahalia S. Desruisseaux, [6]Dazhi Zhao, [7]Gary J Schwartz, [8]Huan Huang, [9]Chris Albanese, [10]Michael P Lisanti, [11]Rajat Singh, [12]Feng Li, [13]Louis M Weiss, [14]Stephen M Factor, [15]Jeffrey E Pessin, [16]Philipp E. Scherer, [17]Herbert B Tanowitz [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2012.11.027
PubMed: 23321322 | Chagas disease [curation]; murine model [curation] | 2013-01-12 |
| Plasma ceramides are elevated in female children and adolescents with type 2 diabetes | [1]Ximena Lopez, [2]Allison B Goldfine, [3]William L Holland, [4]Ruth Gordillo, [5]Philipp E. Scherer [Full author list] | Journal of Pediatric Endocrinology and Metabolism [curation] | DOI: 10.1515/JPEM-2012-0407
PubMed: 23612696 | ceramides [curation]; teenager [curation]; type 2 diabetes [curation] | 2013-01-01 |
| The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism | [1]Yingfeng Deng, [2]Zhao V Wang, [3]Caroline Tao, [4]Ningguo Gao, [5]William L Holland, [6]Anwarul Ferdous, [7]Joyce J Repa, [8]Guosheng Liang, [9]Jin Ye, [10]Mark A Lehrman, [11]Joseph A Hill, [12]Jay D Horton, [13]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI62819
PubMed: 23257357 | | 2012-12-21 |
| Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases | [1]Hee Yun Suk, [2]Chen Zhou, [3]Teddy T C Yang, [4]Hong Zhu, [5]Raymond Y L Yu, [6]Opeyemi Olabisi, [7]XiaoYong Yang, [8]Deborah Brancho, [9]Ja-Young Kim, [10]Philipp E. Scherer, [11]Philippe G. Frank, [12]Michael P. Lisanti, [13]John Calvert, [14]David J Lefer, [15]Jeffery D. Molkentin, [16]Alessandra Ghigo, [17]Emilio Hirsch, [18]Jianping Jin, [19]Chi-Wing Chow [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M112.419150
PubMed: 23258544 | hyperlipidemia [curation] | 2012-12-20 |
| Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction | [1]Kai Sun, [2]Nils Halberg, [3]Mahmood Khan, [4]Ulysses J Magalang, [5]Philipp E. Scherer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00951-12
PubMed: 23249949 | hypoxia [curation] | 2012-12-17 |
| Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer | [1]Jiyoung Park, [2]Venetia R Sarode, [3]David Euhus, [4]Ralf Kittler, [5]Philipp E. Scherer [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1214400109
PubMed: 23213231 | hyperglycemia [curation] | 2012-12-03 |
| Adipose tissue biology and cardiomyopathy: translational implications | [1]Aslan T Turer, [2]Joseph A Hill, [3]Joel K Elmquist, [4]Philipp E. Scherer [Full author list] | Circulation Research [curation] | DOI: 10.1161/CIRCRESAHA.111.262493
PubMed: 23223931 | cardiomyopathy [curation] | 2012-12-01 |
| Metabolic jet lag when the fat clock is out of sync | [1]Ingrid Wernstedt Asterholm, [2]Philipp E. Scherer [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM.3010
PubMed: 23223058 | jet lag [curation] | 2012-12-01 |
| Endotrophin - a novel factor linking obesity with aggressive tumor growth | [1]Jiyoung Park, [2]Philipp E. Scherer [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.796
PubMed: 23455368 | obesity [curation] | 2012-12-01 |
| Adipocyte-derived endotrophin promotes malignant tumor progression | [1]Jiyoung Park, [2]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI63930
PubMed: 23041627 | adipocyte [curation]; tumor progression [curation] | 2012-10-08 |
| Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase | [1]Jorge L Durand, [2]Andrea R Nawrocki, [3]Philipp E. Scherer, [4]Linda A Jelicks [Full author list] | Journal of Cellular Biochemistry [curation] | DOI: 10.1002/JCB.24206
PubMed: 22644792 | endothelium [curation] | 2012-10-01 |
| MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity | [1]Christine M Kusminski, [2]William L Holland, [3]Kai Sun, [4]Jiyoung Park, [5]Stephen B Spurgin, [6]Ying Lin, [7]G Roger Askew, [8]Judith Simcox, [9]Don A McClain, [10]Cai Li, [11]Philipp E. Scherer [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM.2899
PubMed: 22961109 | obesity [curation]; mitochondrion [curation]; adipocyte [curation]; preproinsulin [curation] | 2012-09-09 |
| The cover. Neuroendocrine and endocrine pathways of obesity. | [1]Joel K Elmquist, [2]Philipp E. Scherer [Full author list] | The Journal of the American Medical Association [curation] | DOI: 10.1001/JAMA.2012.3209
PubMed: 22990243 | obesity [curation] | 2012-09-01 |
| Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy | [1]Gemma Fraterrigo, [2]Elisa Fabbrini, [3]Bettina Mittendorfer, [4]Stephen O'Rahilly, [5]Philipp E. Scherer, [6]Bruce W. Patterson, [7]Samuel Klein [Full author list] | Cardiorenal medicine [curation] | DOI: 10.1159/000340037
PubMed: 22969777 | niacinamide [curation] | 2012-07-18 |
| Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance | [1]Meilian Liu, [2]Ruihua Xiang, [3]Sarah Ann Wilk, [4]Ning Zhang, [5]Lauren B Sloane, [6]Kian Azarnoush, [7]Lijun Zhou, [8]Hongzhi Chen, [9]Guangda Xiang, [10]Christi A Walter, [11]Steven N Austad, [12]Nicolas Musi, [13]Ralph A. DeFronzo, [14]Reto Asmis, [15]Philipp E. Scherer, [16]Lily Q Dong, [17]Feng Liu [Full author list] | Diabetes [curation] | DOI: 10.2337/DB12-0169
PubMed: 22807031 | obesity [curation]; insulin resistance [curation]; overexpression [curation] | 2012-07-17 |
| Mitochondrial dysfunction in white adipose tissue | [1]Christine M Kusminski, [2]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/J.TEM.2012.06.004
PubMed: 22784416 | | 2012-07-10 |
| Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity | [1]Jing Liu, [2]Ming Guo, [3]Di Zhang, [4]Shao-Ying Cheng, [5]Meilian Liu, [6]Jun Ding, [7]Philipp E. Scherer, [8]Feng Liu, [9]Xin-Yun Lu [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1202835109
PubMed: 22778410 | | 2012-07-09 |
| The PPARγ-FGF1 axis: an unexpected mediator of adipose tissue homeostasis | [1]Kai Sun, [2]Philipp E. Scherer [Full author list] | Cell Research [curation] | DOI: 10.1038/CR.2012.94
PubMed: 22710798 | tissue homeostasis [curation] | 2012-06-19 |
| Mechanisms of Trypanosoma cruzi persistence in Chagas disease | [1]Fnu Nagajyothi, [2]Fabiana S. Machado, [3]Barbara A Burleigh, [4]Linda A. Jelicks, [5]Philipp E. Scherer, [6]Shankar Mukherjee, [7]Michael P. Lisanti, [8]Louis M. Weiss, [9]Nisha J. Garg, [10]Herbert B Tanowitz [Full author list] | Cellular Microbiology [curation] | DOI: 10.1111/J.1462-5822.2012.01764.X
PubMed: 22309180 | Trypanosoma cruzi [curation]; Chagas disease [curation] | 2012-05-01 |
| Adipokines linking obesity with colorectal cancer risk in postmenopausal women | [1]Gloria Y F Ho, [2]Tao Wang, [3]Marc J Gunter, [4]Howard D Strickler, [5]Mary Cushman, [6]Robert C Kaplan, [7]Sylvia Wassertheil-Smoller, [8]Xiaonan Xue, [9]Swapnil N Rajpathak, [10]Rowan T Chlebowski, [11]Mara Z Vitolins, [12]Philipp E. Scherer, [13]Thomas E Rohan [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-11-2771
PubMed: 22511581 | obesity [curation]; colorectal cancer [curation]; colorectal carcinoma [curation] | 2012-04-17 |
| Lack of "immunological fitness" during fasting in metabolically challenged animals | [1]Ingrid Wernstedt Asterholm, [2]John McDonald, [3]Pierre-Gilles Blanchard, [4]Madhur Sinha, [5]Qiang Xiao, [6]Jehangir Mistry, [7]Joseph M. Rutkowski, [8]Yves Deshaies, [9]Rolf A Brekken, [10]Philipp E. Scherer [Full author list] | Journal of Lipid Research [curation] | DOI: 10.1194/JLR.M021725
PubMed: 22504909 | immunology [curation] | 2012-04-13 |
| Dichotomous effects of VEGF-A on adipose tissue dysfunction | [1]Kai Sun, [2]Ingrid Wernstedt Asterholm, [3]Christine M Kusminski, [4]Ana Carolina Bueno, [5]Zhao V Wang, [6]Jeffrey W Pollard, [7]Rolf A Brekken, [8]Philipp E. Scherer [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1200447109
PubMed: 22451920 | | 2012-03-26 |
| Race-ethnic differences in adipokine levels: the Study of Women's Health Across the Nation (SWAN). | [1]Unab I Khan, [2]Dan Wang, [3]Mary Frances Roy Sowers, [4]Peter Mancuso, [5]Susan A Everson-Rose, [6]Philipp E. Scherer, [7]Rachel P. Wildman [Full author list] | Metabolism [curation] | DOI: 10.1016/J.METABOL.2012.02.005
PubMed: 22444780 | | 2012-03-22 |
| Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study | [1]Aslan T Turer, [2]Jeffrey D Browning, [3]Colby R Ayers, [4]Sandeep R Das, [5]Amit Khera, [6]Gloria L. Vega, [7]Scott M. Grundy, [8]Philipp E. Scherer [Full author list] | The Journal of Clinical Endocrinology and Metabolism [curation] | DOI: 10.1210/JC.2011-3305
PubMed: 22438228 | steatosis [curation] | 2012-03-21 |
| Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1. | [1]Ingrid Wernstedt Asterholm, [2]Dorothy I Mundy, [3]Jian Weng, [4]Richard G W Anderson, [5]Philipp E. Scherer [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2012.01.004
PubMed: 22326219 | | 2012-02-01 |
| Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). | [1]Fnu Nagajyothi, [2]Mahalia S. Desruisseaux, [3]Fabiana S Machado, [4]Rajendra Upadhya, [5]Dazhi Zhao, [6]Gary J Schwartz, [7]Mauro M Teixeira, [8]Chris Albanese, [9]Michael P. Lisanti, [10]Streamson C Chua, [11]Louis M Weiss, [12]Philipp E. Scherer, [13]Herbert B Tanowitz [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1093/INFDIS/JIR840
PubMed: 22293433 | Brazil [curation]; Trypanosoma cruzi [curation] | 2012-01-31 |
| Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis | [1]Congcong He, [2]Michael C Bassik, [3]Viviana Moresi, [4]Kai Sun, [5]Yongjie Wei, [6]Zhongju Zou, [7]Zhenyi An, [8]Joy Loh, [9]Jill Fisher, [10]Qihua Sun, [11]Stanley J. Korsmeyer, [12]Milton Packer, [13]Herman I May, [14]Joseph A Hill, [15]Herbert W. Virgin, [16]Christopher Gilpin, [17]Guanghua Xiao, [18]Rhonda Bassel-Duby, [19]Philipp E. Scherer, [20]Beth Levine [Full author list] | Nature [curation] | DOI: 10.1038/NATURE10758
PubMed: 22258505 | glucose [curation]; autophagy [curation]; B cell leukemia/lymphoma 2 [curation]; Beclin 1, autophagy related [curation] | 2012-01-26 |
| Enhanced fatty acid flux triggered by adiponectin overexpression | [1]Shoba Shetty, [2]Maria A Ramos-Roman, [3]You-Ree Cho, [4]Jonathan Brown, [5]Jorge Plutzky, [6]Eric S Muise, [7]Jay D Horton, [8]Philipp E. Scherer, [9]Elizabeth Parks [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2011-1339
PubMed: 22045665 | fatty acid [curation]; overexpression [curation] | 2011-11-01 |
| Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages | [1]Pamela Fischer-Posovszky, [2]Qiong A Wang, [3]Ingrid Wernstedt Asterholm, [4]Joseph M. Rutkowski, [5]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2011-1031
PubMed: 21693678 | macrophage [curation]; adipocyte [curation]; apoptotic process [curation] | 2011-06-21 |
| Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease | [1]Adaliene Versiani Matos Ferreira, [2]Marcela Segatto, [3]Zélia Menezes, [4]Andréa Mara Macedo, [5]Cláudio Gelape, [6]Luciana de Oliveira Andrade, [7]Fnu Nagajyothi, [8]Philipp E. Scherer, [9]Mauro Martins Teixeira, [10]Herbert B Tanowitz [Full author list] | Microbes and Infection [curation] | DOI: 10.1016/J.MICINF.2011.06.002
PubMed: 21726660 | Trypanosoma cruzi [curation]; Chagas disease [curation] | 2011-06-21 |
| Paracrine and endocrine effects of adipose tissue on cancer development and progression | [1]Jiyoung Park, [2]David M Euhus, [3]Philipp E. Scherer [Full author list] | Endocrine Reviews [curation] | DOI: 10.1210/ER.2010-0030
PubMed: 21642230 | | 2011-06-02 |
| Adipose tissue remodeling and obesity | [1]Kai Sun, [2]Christine M Kusminski, [3]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI45887
PubMed: 21633177 | obesity [curation] | 2011-06-01 |
| Adiponectin regulation of stellate cell activation via PPARγ-dependent and -independent mechanisms | [1]Mahnoush S Shafiei, [2]Shoba Shetty, [3]Philipp E. Scherer, [4]Don C Rockey [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2011.02.035
PubMed: 21641391 | | 2011-06-01 |
| Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling | [1]Russell A Miller, [2]Qingwei Chu, [3]John Le Lay, [4]Philipp E. Scherer, [5]Rexford S Ahima, [6]Klaus H Kaestner, [7]Marc Foretz, [8]Benoit Viollet, [9]Morris J. Birnbaum [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI45942
PubMed: 21606593 | | 2011-05-23 |
| Adiponectin and cardiovascular risk profile in patients with type 2 diabetes mellitus: parameters associated with adiponectin complex distribution | [1]Mark P Hamilton, [2]M Odette Gore, [3]Colby R Ayers, [4]Xinyu Wu, [5]Darren K McGuire, [6]Philipp E. Scherer [Full author list] | Diabetes and Vascular Disease Research [curation] | DOI: 10.1177/1479164111407784
PubMed: 21555334 | type 2 diabetes [curation] | 2011-05-09 |
| Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease | [1]Megan M Lo, [2]Shelia Salisbury, [3]Philipp E. Scherer, [4]Susan L Furth, [5]Bradley A Warady, [6]Mark M Mitsnefes [Full author list] | Pediatric Nephrology [curation] | DOI: 10.1007/S00467-011-1906-X
PubMed: 21553321 | | 2011-05-08 |
| Resistin, but not adiponectin and leptin, is associated with the risk of ischemic stroke among postmenopausal women: results from the Women's Health Initiative | [1]Swapnil N Rajpathak, [2]Robert C Kaplan, [3]Sylvia Wassertheil-Smoller, [4]Mary Cushman, [5]Thomas E Rohan, [6]Aileen P McGinn, [7]Tao Wang, [8]Howard D Strickler, [9]Philipp E. Scherer, [10]Rachel H. Mackey, [11]J. David Curb, [12]Gloria Y F Ho [Full author list] | Stroke Journal [curation] | DOI: 10.1161/STROKEAHA.110.607853
PubMed: 21546486 | | 2011-05-05 |
| Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice | [1]William L Holland, [2]Benjamin T Bikman, [3]Li-Ping Wang, [4]Guan Yuguang, [5]Katherine M Sargent, [6]Sarada Bulchand, [7]Trina A Knotts, [8]Guanghou Shui, [9]Deborah J. Clegg, [10]Markus R. Wenk, [11]Michael J Pagliassotti, [12]Philipp E. Scherer, [13]Scott A Summers [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI43378
PubMed: 21490391 | fatty acid [curation]; toll-like receptor [curation]; ceramides [curation]; insulin resistance [curation]; preproinsulin [curation] | 2011-04-01 |
| A prospective study of inflammation markers and endometrial cancer risk in postmenopausal hormone nonusers | [1]Tao Wang, [2]Thomas E Rohan, [3]Marc J Gunter, [4]Xiaonan Xue, [5]Jean Wactawski-Wende, [6]Swapnil N Rajpathak, [7]Mary Cushman, [8]Howard D Strickler, [9]Robert C Kaplan, [10]Sylvia Wassertheil-Smoller, [11]Philipp E. Scherer, [12]Gloria Y F Ho [Full author list] | Cancer Epidemiology, Biomarkers & Prevention [curation] | DOI: 10.1158/1055-9965.EPI-10-1222
PubMed: 21415362 | endometrial cancer [curation] | 2011-03-17 |
| Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts | [1]Casey Trimmer, [2]Federica Sotgia, [3]Diana Whitaker-Menezes, [4]Renee M Balliet, [5]Gregory Eaton, [6]Ubaldo E Martinez-Outschoorn, [7]Stephanos Pavlides, [8]Anthony Howell, [9]Renato V. Iozzo, [10]Richard Pestell, [11]Philipp E. Scherer, [12]Franco Capozza, [13]Michael P Lisanti [Full author list] | Cancer Biology and Therapy [curation] | DOI: 10.4161/CBT.11.4.14101
PubMed: 21150282 | | 2011-02-15 |
| Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion | [1]Fnu Nagajyothi, [2]Louis M Weiss, [3]David L. Silver, [4]Mahalia S. Desruisseaux, [5]Philipp E. Scherer, [6]Joachim Herz, [7]Herbert B Tanowitz [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0000953
PubMed: 21408103 | lipoprotein [curation]; Trypanosoma cruzi [curation] | 2011-02-01 |
| Adipose tissue, diabetes and Chagas disease | [1]Herbert B Tanowitz, [2]Linda A Jelicks, [3]Fabiana S Machado, [4]Lisia Esper, [5]Xiaohua Qi, [6]Mahalia S. Desruisseaux, [7]Streamson C Chua, [8]Philipp E. Scherer, [9]Fnu Nagajyothi [Full author list] | Advances in Parasitology [curation] | DOI: 10.1016/B978-0-12-385895-5.00010-4
PubMed: 21884894 | Chagas disease [curation] | 2011-01-01 |
| Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin | [1]William L Holland, [2]Russell A Miller, [3]Zhao V Wang, [4]Kai Sun, [5]Brian M Barth, [6]Hai H Bui, [7]Kathryn E Davis, [8]Benjamin T Bikman, [9]Nils Halberg, [10]Joseph M. Rutkowski, [11]Mark R Wade, [12]Vincent M Tenorio, [13]Ming-Shang Kuo, [14]Joseph T Brozinick, [15]Bei B Zhang, [16]Morris J. Birnbaum, [17]Scott A Summers, [18]Philipp E. Scherer [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM.2277
PubMed: 21186369 | pleiotropy [curation] | 2010-12-26 |
| Adiponectin decreases pulmonary arterial remodeling in murine models of pulmonary hypertension | [1]Meiqian Weng, [2]Michael J Raher, [3]Patricio Leyton, [4]Terry P Combs, [5]Philipp E. Scherer, [6]Kenneth D Bloch, [7]Benjamin D Medoff [Full author list] | American Journal of Respiratory Cell and Molecular Biology [curation] | DOI: 10.1165/RCMB.2010-0316OC
PubMed: 21075862 | murine model [curation] | 2010-11-12 |
| Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo | [1]Jiyoung Park, [2]Christine M Kusminski, [3]Streamson C Chua, [4]Philipp E. Scherer [Full author list] | The American Journal of Pathology [curation] | DOI: 10.2353/AJPATH.2010.100595
PubMed: 21056997 | | 2010-11-05 |
| Adipokines as novel biomarkers and regulators of the metabolic syndrome | [1]Yingfeng Deng, [2]Philipp E. Scherer [Full author list] | Annals of the New York Academy of Sciences [curation] | DOI: 10.1111/J.1749-6632.2010.05875.X
PubMed: 21276002 | metabolic syndrome [curation]; biomarker [curation] | 2010-11-01 |
| 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver | [1]Yong Xu, [2]Eric D Berglund, [3]Jong-Woo Sohn, [4]William L Holland, [5]Jen-Chieh Chuang, [6]Makoto Fukuda, [7]Jari Rossi, [8]Kevin W. Williams, [9]Juli E Jones, [10]Jeffrey M Zigman, [11]Bradford B Lowell, [12]Philipp E. Scherer, [13]Joel K Elmquist [Full author list] | Nature Neuroscience [curation] | DOI: 10.1038/NN.2664
PubMed: 21037584 | preproinsulin [curation] | 2010-10-31 |
| Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection | [1]Fnu Nagajyothi, [2]Dazhi Zhao, [3]Fabiana S Machado, [4]Louis M Weiss, [5]Gary J Schwartz, [6]Mahalia S. Desruisseaux, [7]Yang Zhao, [8]Stephen M. Factor, [9]Huan Huang, [10]Chris Albanese, [11]Mauro M Teixeira, [12]Philipp E. Scherer, [13]Streamson C Chua, [14]Herbert B Tanowitz [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1086/656189
PubMed: 20726767 | Brazil [curation]; Trypanosoma cruzi [curation] | 2010-10-01 |
| Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D | [1]Hong Zhu, [2]Hee Yun Suk, [3]Raymond Y L Yu, [4]Deborah Brancho, [5]Opeyemi Olabisi, [6]Teddy T C Yang, [7]XiaoYong Yang, [8]Jialin Zhang, [9]Mustapha Moussaif, [10]Jorge L Durand, [11]Linda A Jelicks, [12]Ja-Young Kim, [13]Philipp E. Scherer, [14]Philippe G. Frank, [15]Michael P. Lisanti, ... [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.01193-09
PubMed: 20647544 | | 2010-07-20 |
| Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes | [1]Alethia Villasenor, [2]Zhao V Wang, [3]Lee B Rivera, [4]Özhan Öcal, [5]Ingrid Wernstedt Asterholm, [6]Philipp E. Scherer, [7]Rolf A Brekken, [8]Ondine Cleaver, [9]Thomas M Wilkie [Full author list] | Disease Models & Mechanisms [curation] | DOI: 10.1242/DMM.003210
PubMed: 20616094 | pancreas [curation] | 2010-07-08 |
| Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes. | [1]Shira Landskroner-Eiger, [2]Jiyoung Park, [3]Davelene Israel, [4]Jeffrey W Pollard, [5]Philipp E. Scherer [Full author list] | Developmental Biology [curation] | DOI: 10.1016/J.YDBIO.2010.06.019
PubMed: 20599899 | adipocyte [curation]; morphogenesis [curation] | 2010-06-19 |
| Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model | [1]Sarada Vissapragada, [2]Anup Ghosh, [3]Lymor Ringer, [4]Patricia Salinas, [5]Amanda Brophy, [6]Daniel Peaceman, [7]Bhaskar Kallakury, [8]Partha P Banerjee, [9]Stanley T Fricke, [10]William Helfrich, [11]Yi Chien Lee, [12]Richard Pestell, [13]Philipp E. Scherer, [14]Herbert B Tanowitz, [15]Maria Laura Avantaggiati, [16]Leena Hilakivi-Clarke, [17]Michael P. Lisanti, [18]Olga C Rodriguez, [19]Chris Albanese [Full author list] | Cell Cycle [curation] | DOI: 10.4161/CC.9.9.11542
PubMed: 20404514 | fatty acid [curation] | 2010-05-15 |
| Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility | [1]Jennifer Hill, [2]Carol F Elias, [3]Makoto Fukuda, [4]Kevin W. Williams, [5]Eric D Berglund, [6]William L Holland, [7]You-Ree Cho, [8]Jen-Chieh Chuang, [9]Yong Xu, [10]Michelle Choi, [11]Danielle Lauzon, [12]Charlotte E Lee, [13]Roberto Coppari, [14]James A Richardson, [15]Jeffrey M Zigman, [16]Streamson Chua, [17]Philipp E. Scherer, [18]Bradford B Lowell, [19]Jens C Brüning, [20]Joel K Elmquist [Full author list] | Cell Metabolism [curation] | DOI: 10.1016/J.CMET.2010.03.002
PubMed: 20374961 | cell biology [curation]; glucose [curation]; glycobiology [curation]; preproinsulin [curation] | 2010-04-07 |
| Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression | [1]Zhao V Wang, [2]Yingfeng Deng, [3]Qiong A Wang, [4]Kai Sun, [5]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2010-0136
PubMed: 20363877 | adipocyte [curation] | 2010-04-02 |
| Lack of association between adiponectin levels and atherosclerosis in mice | [1]Andrea R Nawrocki, [2]Susanna M Hofmann, [3]Daniel Teupser, [4]Joshua E Basford, [5]Jorge L Durand, [6]Linda A Jelicks, [7]Connie W Woo, [8]George Kuriakose, [9]Stephen M Factor, [10]Herbert B Tanowitz, [11]David Y Hui, [12]Ira Tabas, [13]Philipp E. Scherer [Full author list] | Arteriosclerosis, Thrombosis, and Vascular Biology [curation] | DOI: 10.1161/ATVBAHA.109.195826
PubMed: 20299691 | atherosclerosis [curation] | 2010-03-18 |
| Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity | [1]Roger H Unger, [2]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/J.TEM.2010.01.009
PubMed: 20223680 | metabolic syndrome [curation] | 2010-03-10 |
| Hepatocyte growth factor and the risk of ischemic stroke developing among postmenopausal women: results from the Women's Health Initiative | [1]Swapnil N Rajpathak, [2]Tao Wang, [3]Sylvia Wassertheil-Smoller, [4]Howard D Strickler, [5]Robert C Kaplan, [6]Aileen P McGinn, [7]Rachel P. Wildman, [8]Daniel Rosenbaum, [9]Thomas E Rohan, [10]Philipp E. Scherer, [11]Mary Cushman, [12]Gloria Y F Ho [Full author list] | Stroke Journal [curation] | DOI: 10.1161/STROKEAHA.109.567719
PubMed: 20203323 | | 2010-03-04 |
| Adipocyte-derived factors potentiate nutrient-induced production of plasminogen activator inhibitor-1 by macrophages | [1]Preeti Kishore, [2]Weijie Li, [3]Julia Tonelli, [4]Do-Eun Lee, [5]Sudha Koppaka, [6]Kehao Zhang, [7]Ying Lin, [8]Sylvia Kehlenbrink, [9]Philipp E. Scherer, [10]Meredith Hawkins [Full author list] | Science Translational Medicine [curation] | DOI: 10.1126/SCITRANSLMED.3000292
PubMed: 20371491 | adipocyte [curation]; plasminogen [curation] | 2010-02-01 |
| Enhanced metabolic flexibility associated with elevated adiponectin levels | [1]Ingrid Wernstedt Asterholm, [2]Philipp E. Scherer [Full author list] | The American Journal of Pathology [curation] | DOI: 10.2353/AJPATH.2010.090647
PubMed: 20093494 | metabolic flexibility [curation] | 2010-01-21 |
| Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes | [1]Cecile Vernochet, [2]Kathryn E Davis, [3]Philipp E. Scherer, [4]Stephen R Farmer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2009-1057
PubMed: 19952271 | adipocyte [curation] | 2009-12-01 |
| Diabetes and apoptosis: lipotoxicity | [1]Christine M Kusminski, [2]Shoba Shetty, [3]Lelio Orci, [4]Roger H Unger, [5]Philipp E. Scherer [Full author list] | Apoptosis [curation] | DOI: 10.1007/S10495-009-0352-8
PubMed: 19421860 | apoptotic process [curation] | 2009-12-01 |
| Lipid homeostasis, lipotoxicity and the metabolic syndrome. | [1]Roger H Unger, [2]Gregory O Clark, [3]Philipp E. Scherer, [4]Lelio Orci [Full author list] | Biochimica et Biophysica Acta [curation] | DOI: 10.1016/J.BBALIP.2009.10.006
PubMed: 19948243 | metabolic syndrome [curation] | 2009-11-27 |
| Impact of simvastatin on adipose tissue: pleiotropic effects in vivo | [1]Tayeba Khan, [2]Mark P Hamilton, [3]Dorothy I Mundy, [4]Streamson C Chua, [5]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2009-0603
PubMed: 19819942 | simvastatin [curation]; pleiotropy [curation] | 2009-10-09 |
| Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue | [1]Joseph M Rutkowski, [2]Kathryn E Davis, [3]Philipp E. Scherer [Full author list] | FEBS Journal [curation] | DOI: 10.1111/J.1742-4658.2009.07303.X
PubMed: 19754873 | pathology [curation]; obesity [curation] | 2009-09-15 |
| Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome | [1]Fnu Nagajyothi, [2]Mahalia S Desruisseaux, [3]Linda A Jelicks, [4]Fabiana S Machado, [5]Streamson Chua, [6]Philipp E. Scherer, [7]Herbert B Tanowitz [Full author list] | Interdisciplinary Perspectives on Infectious Diseases [curation] | DOI: 10.1155/2009/824324
PubMed: 19644556 | Chagas disease [curation]; metabolic syndrome [curation] | 2009-07-26 |
| Systemic fate of the adipocyte-derived factor adiponectin | [1]Nils Halberg, [2]Todd D Schraw, [3]Zhao V Wang, [4]Ja-Young Kim, [5]James Yi, [6]Mark P Hamilton, [7]Kate Luby-Phelps, [8]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB08-1750
PubMed: 19581422 | adipocyte [curation] | 2009-07-06 |
| The transcriptional response of the islet to pregnancy in mice | [1]Sebastian Rieck, [2]Peter White, [3]Jonathan Schug, [4]Alan J Fox, [5]Olga Smirnova, [6]Nan Gao, [7]Rana K Gupta, [8]Zhao V Wang, [9]Philipp E. Scherer, [10]Mark P Keller, [11]Alan D Attie, [12]Klaus H Kaestner [Full author list] | Molecular Endocrinology [curation] | DOI: 10.1210/ME.2009-0144
PubMed: 19574445 | | 2009-07-02 |
| Chagas disease, adipose tissue and the metabolic syndrome | [1]Fnu Nagajyothi, [2]Mahalia S. Desruisseaux, [3]Louis M Weiss, [4]Streamson C Chua, [5]Chris Albanese, [6]Fabiana S Machado, [7]Lisia Esper, [8]Michael P. Lisanti, [9]Mauro M Teixeira, [10]Philipp E. Scherer, [11]Herbert B Tanowitz [Full author list] | Memórias do Instituto Oswaldo Cruz [curation] | DOI: 10.1590/S0074-02762009000900028
PubMed: 19753477 | Chagas disease [curation]; metabolic syndrome [curation] | 2009-07-01 |
| C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists | [1]Cecile Vernochet, [2]Sidney B Peres, [3]Kathryn E Davis, [4]Meghan E McDonald, [5]Li Qiang, [6]Hong Wang, [7]Philipp E. Scherer, [8]Stephen R Farmer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.01899-08
PubMed: 19564408 | phenotype [curation]; adipocyte [curation] | 2009-06-29 |
| Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue | [1]Nils Halberg, [2]Tayeba Khan, [3]Maria E Trujillo, [4]Ingrid Wernstedt Asterholm, [5]Alan D Attie, [6]Shariq Sherwani, [7]Zhao V Wang, [8]Shira Landskroner-Eiger, [9]Sean P Dineen, [10]Ulysses J Magalang, [11]Rolf A Brekken, [12]Philipp E. Scherer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00192-09
PubMed: 19546236 | hypoxia [curation]; insulin resistance [curation]; preproinsulin [curation] | 2009-06-22 |
| Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo | [1]Shira Landskroner-Eiger, [2]Binzhi Qian, [3]Eric S Muise, [4]Andrea R Nawrocki, [5]Joel P Berger, [6]Eugene J Fine, [7]Wade Koba, [8]Yingfeng Deng, [9]Jeffrey W Pollard, [10]Philipp E. Scherer [Full author list] | Clinical Cancer Research [curation] | DOI: 10.1158/1078-0432.CCR-08-2649
PubMed: 19447867 | | 2009-05-15 |
| Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies | [1]Shoba Shetty, [2]Christine M Kusminski, [3]Philipp E. Scherer [Full author list] | Trends in Pharmacological Sciences [curation] | DOI: 10.1016/J.TIPS.2009.02.004
PubMed: 19359049 | | 2009-04-07 |
| PAQRs: a counteracting force to ceramides? | [1]William L Holland, [2]Philipp E. Scherer [Full author list] | Molecular Pharmacology [curation] | DOI: 10.1124/MOL.109.054817
PubMed: 19158359 | ceramides [curation] | 2009-01-21 |
| Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI | [1]Tayeba Khan, [2]Eric S Muise, [3]Puneeth Iyengar, [4]Zhao V Wang, [5]Manisha Chandalia, [6]Nicola Abate, [7]Bei B Zhang, [8]Paolo Bonaldo, [9]Streamson Chua, [10]Philipp E. Scherer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.01300-08
PubMed: 19114551 | | 2008-12-29 |
| Adiponectin: no longer the lone soul in the fight against insulin resistance? | [1]Kathryn E Davis, [2]Philipp E. Scherer [Full author list] | Biochemical Journal [curation] | DOI: 10.1042/BJ20082033
PubMed: 18990088 | insulin resistance [curation] | 2008-12-01 |
| DsbA-L is a versatile player in adiponectin secretion | [1]Zhao V Wang, [2]Philipp E. Scherer [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.0810027105
PubMed: 19020096 | | 2008-11-19 |
| Adipocyte metabolism and obesity | [1]Alan D Attie, [2]Philipp E. Scherer [Full author list] | Journal of Lipid Research [curation] | DOI: 10.1194/JLR.R800057-JLR200
PubMed: 19017614 | obesity [curation]; adipocyte [curation] | 2008-11-17 |
| Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype | [1]Fnu Nagajyothi, [2]Mahalia S. Desruisseaux, [3]Niranjan Thiruvur, [4]Louis M Weiss, [5]Vicki L Braunstein, [6]Chris Albanese, [7]Mauro M Teixeira, [8]Cecilia J de Almeida, [9]Michael P. Lisanti, [10]Philipp E. Scherer, [11]Herbert B Tanowitz [Full author list] | Obesity [curation] | DOI: 10.1038/OBY.2008.331
PubMed: 19186325 | inflammation [curation]; phenotype [curation]; Trypanosoma cruzi [curation]; adipocyte [curation] | 2008-09-01 |
| The adipocyte as an endocrine cell | [1]Nils Halberg, [2]Ingrid Wernstedt Asterholm, [3]Philipp E. Scherer [Full author list] | Endocrinology and Metabolism Clinics of North America [curation] | DOI: 10.1016/J.ECL.2008.07.002
PubMed: 18775362 | adipocyte [curation] | 2008-09-01 |
| The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes | [1]Grit Sommer, [2]Sebastian Weise, [3]Susan Kralisch, [4]Philipp E. Scherer, [5]Ulrike Lössner, [6]Matthias Blüher, [7]Michael Stumvoll, [8]Mathias Fasshauer [Full author list] | Journal of Cellular Biochemistry [curation] | DOI: 10.1002/JCB.21782
PubMed: 18452164 | adipocyte [curation] | 2008-08-01 |
| PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation | [1]Zhao V Wang, [2]James Mu, [3]Todd D Schraw, [4]Laurent Gautron, [5]Joel K Elmquist, [6]Bei B Zhang, [7]Michael Brownlee, [8]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB07-1631
PubMed: 18469203 | | 2008-05-09 |
| Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism | [1]Patrice Dallaire, [2]Kerstin Bellmann, [3]Mathieu Laplante, [4]Stéphanie Gélinas, [5]Carolina Centeno-Baez, [6]Patrice Penfornis, [7]Marie-Line Peyot, [8]Martin G Latour, [9]Julien Lamontagne, [10]Maria E Trujillo, [11]Philipp E. Scherer, [12]Marc Prentki, [13]Yves Deshaies, [14]André Marette [Full author list] | Diabetes [curation] | DOI: 10.2337/DB08-0540
PubMed: 18458147 | obesity [curation] | 2008-05-05 |
| Adiponectin levels and genotype: a potential regulator of life span in humans | [1]Gil Atzmon, [2]Toni I Pollin, [3]Jill Crandall, [4]Keith Tanner, [5]Clyde B Schechter, [6]Philipp E. Scherer, [7]Marielisa Rincon, [8]Glenn Siegel, [9]Micol Katz, [10]Richard B. Lipton, [11]Alan R Shuldiner, [12]Nir Barzilai [Full author list] | The Journals of Gerontology [curation] | DOI: 10.1093/GERONA/63.5.447
PubMed: 18511746 | lifetime [curation] | 2008-05-01 |
| Plasma adiponectin complexes have distinct biochemical characteristics | [1]Todd Schraw, [2]Zhao V Wang, [3]Nils Halberg, [4]Meredith Hawkins, [5]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2007-1561
PubMed: 18202126 | | 2008-01-17 |
| Adiponectin, cardiovascular function, and hypertension | [1]Zhao V Wang, [2]Philipp E. Scherer [Full author list] | Hypertension [curation] | DOI: 10.1161/HYPERTENSIONAHA.107.099424
PubMed: 17998473 | circulatory system [curation] | 2007-11-12 |
| Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA. | [1]Madhur K Sinha, [2]Traci Songer, [3]Qiang Xiao, [4]John H Sloan, [5]Jin Wang, [6]Shaoquen Ji, [7]William E Alborn, [8]Randy A Davis, [9]Michael M Swarbrick, [10]Kimber L Stanhope, [11]Bruce Wolfe, [12]Peter J Havel, [13]Todd Schraw, [14]Robert J Konrad, [15]Philipp E. Scherer, [16]Jehangir S Mistry [Full author list] | Clinical Chemistry [curation] | DOI: 10.1373/CLINCHEM.2007.090670
PubMed: 17951289 | | 2007-10-19 |
| Obesity-associated improvements in metabolic profile through expansion of adipose tissue | [1]Ja-Young Kim, [2]Esther van de Wall, [3]Mathieu Laplante, [4]Anthony Azzara, [5]Maria E Trujillo, [6]Susanna M Hofmann, [7]Todd Schraw, [8]Jorge L Durand, [9]Hua Li, [10]Guangyu Li, [11]Linda A Jelicks, [12]Mark F Mehler, [13]David Y Hui, [14]Yves Deshaies, [15]Gerald I. Shulman, [16]Gary J Schwartz, [17]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI31021
PubMed: 17717599 | obesity [curation] | 2007-09-01 |
| Within-individual stability of obesity-related biomarkers among women | [1]Robert C Kaplan, [2]Gloria Y F Ho, [3]XiaoNan Xue, [4]Swapnil Rajpathak, [5]Mary Cushman, [6]Thomas E Rohan, [7]Howard D Strickler, [8]Philipp E. Scherer, [9]Kathryn M. Anastos [Full author list] | Cancer Epidemiology, Biomarkers & Prevention [curation] | DOI: 10.1158/1055-9965.EPI-06-1089
PubMed: 17548700 | obesity [curation]; biomarker [curation] | 2007-06-01 |
| Hypothalamic resistin induces hepatic insulin resistance | [1]Evan D Muse, [2]Tony K T Lam, [3]Philipp E. Scherer, [4]Luciano Rossetti [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI30440
PubMed: 17525801 | insulin resistance [curation]; preproinsulin [curation] | 2007-05-24 |
| Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects | [1]Rita Basu, [2]Utpal B Pajvani, [3]Robert A Rizza, [4]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB07-0185
PubMed: 17513700 | type 2 diabetes [curation] | 2007-05-18 |
| Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice | [1]Hua Lin, [2]Ja-Young Kim, [3]Alessandro Pocai, [4]Luciano Rossetti, [5]Lawrence Shapiro, [6]Philipp E. Scherer, [7]Domenico Accili [Full author list] | Diabetes [curation] | DOI: 10.2337/DB07-0127
PubMed: 17475934 | insulin resistance [curation] | 2007-05-02 |
| Thromboxane A2is a key regulator of pathogenesis duringTrypanosoma cruziinfection | [1]Anthony W. Ashton, [2]Shankar Mukherjee, [3]FNU Nagajyothi, [4]Huan Huang, [5]Vicki L. Braunstein, [6]Mahalia S. Desruisseaux, [7]Stephen M. Factor, [8]Lillie Lopez, [9]Joan W. Berman, [10]Murray Wittner, [11]Philipp E. Scherer, [12]Valerie Capra, [13]Thomas M. Coffman, [14]Charles N Serhan, [15]Katherine Gotlinger, [16]Kenneth K. Wu, [17]Louis M. Weiss, [18]Herbert B Tanowitz [Full author list] | Journal of Cell Biology [curation] | DOI: 10.1083/JCB1772OIA4
| | 2007-04-23 |
| Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection | [1]Anthony W Ashton, [2]Shankar Mukherjee, [3]F N U Nagajyothi, [4]Huan Huang, [5]Vicki L Braunstein, [6]Mahalia S Desruisseaux, [7]Stephen M Factor, [8]Lillie Lopez, [9]Joan W Berman, [10]Murray Wittner, [11]Philipp E. Scherer, [12]Valerie Capra, [13]Thomas M Coffman, [14]Charles N Serhan, [15]Katherine Gotlinger, [16]Kenneth K Wu, [17]Louis M Weiss, [18]Herbert B Tanowitz [Full author list] | Journal of Experimental Medicine [curation] | DOI: 10.1084/JEM.20062432
PubMed: 17420269 | Trypanosoma cruzi [curation]; pathogenesis [curation] | 2007-04-09 |
| Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention | [1]Zhao V Wang, [2]Todd D Schraw, [3]Ja-Young Kim, [4]Tayeba Khan, [5]Michael W Rajala, [6]Antonia Follenzi, [7]Philipp E. Scherer [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00931-06
PubMed: 17353260 | adipocyte [curation] | 2007-03-12 |
| Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. | [1]Miriam Cnop, [2]Josep Vidal, [3]Rebecca L Hull, [4]Kristina M Utzschneider, [5]Darcy B Carr, [6]Todd Schraw, [7]Philipp E. Scherer, [8]Edward J. Boyko, [9]Wilfred Y Fujimoto, [10]Steven E. Kahn [Full author list] | Diabetes Care [curation] | DOI: 10.2337/DC06-1834
PubMed: 17327340 | type 2 diabetes [curation] | 2007-03-01 |
| Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies | [1]Robert K Semple, [2]Nils Halberg, [3]Keith Burling, [4]Maria A Soos, [5]Todd Schraw, [6]Jian'an Luan, [7]Elaine K Cochran, [8]David B. Dunger, [9]Nicholas J. Wareham, [10]Philipp E. Scherer, [11]Phillip Gorden, [12]Stephen O'Rahilly [Full author list] | Diabetes [curation] | DOI: 10.2337/DB06-1665
PubMed: 17325257 | antibody [curation]; insulin resistance [curation]; preproinsulin [curation] | 2007-02-26 |
| Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2 | [1]Jane J Kim, [2]Yoshiaki Kido, [3]Philipp E. Scherer, [4]Morris F White, [5]Domenico Accili [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00430.2006
PubMed: 17299086 | | 2007-02-13 |
| Visceral fat adipokine secretion is associated with systemic inflammation in obese humans | [1]Luigi Fontana, [2]J Christopher Eagon, [3]Maria E Trujillo, [4]Philipp E. Scherer, [5]Samuel Klein [Full author list] | Diabetes [curation] | DOI: 10.2337/DB06-1656
PubMed: 17287468 | systemic inflammation [curation] | 2007-02-07 |
| Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle. | [1]Weijie Li, [2]Julia Tonelli, [3]Preeti Kishore, [4]Randall Owen, [5]Elliot Goodman, [6]Philipp E. Scherer, [7]Meredith Hawkins [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00312.2006
PubMed: 17213476 | preproinsulin [curation] | 2007-01-09 |
| Mouse Models of Lipodystrophy Key reagents for the understanding of the metabolic syndrome | [1]Ingrid Wernstedt Asterholm, [2]Nils Halberg, [3]Philipp E. Scherer [Full author list] | Drug discovery today. Disease models [curation] | DOI: 10.1016/J.DDMOD.2007.10.003
PubMed: 18193096 | metabolic syndrome [curation] | 2007-01-01 |
| Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein | [1]Gino Castriota, [2]G Marie Thompson, [3]Ying Lin, [4]Philipp E. Scherer, [5]David E Moller, [6]Joel P Berger [Full author list] | Cell Biology International [curation] | DOI: 10.1016/J.CELLBI.2006.11.033
PubMed: 17240171 | adipocyte [curation] | 2006-12-15 |
| Brain adipocytokine action and metabolic regulation | [1]Rexford S Ahima, [2]Yong Qi, [3]Neel S Singhal, [4]Malaka B Jackson, [5]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB06-S018
PubMed: 17130638 | | 2006-12-01 |
| Adipocyte, adipose tissue, and infectious disease | [1]Mahalia S Desruisseaux, [2]Nagajyothi, [3]Maria E Trujillo, [4]Herbert B Tanowitz, [5]Philipp E. Scherer [Full author list] | Infection and Immunity [curation] | DOI: 10.1128/IAI.01455-06
PubMed: 17118983 | adipocyte [curation] | 2006-11-21 |
| Loss of resistin improves glucose homeostasis in leptin deficiency | [1]Yong Qi, [2]Zhenying Nie, [3]Yun-Sik Lee, [4]Neel S Singhal, [5]Philipp E. Scherer, [6]Mitchell A Lazar, [7]Rexford S Ahima [Full author list] | Diabetes [curation] | DOI: 10.2337/DB05-0615
PubMed: 17065346 | | 2006-11-01 |
| Adipose tissue-derived factors: impact on health and disease | [1]Maria E Trujillo, [2]Philipp E. Scherer [Full author list] | Endocrine Reviews [curation] | DOI: 10.1210/ER.2006-0033
PubMed: 17056740 | | 2006-10-20 |
| Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study | [1]Adrien Kettaneh, [2]Barbara Heude, [3]Jean-Michel Oppert, [4]Philipp E. Scherer, [5]David Meyre, [6]Jean-Michel Borys, [7]Pierre Ducimetière, [8]Marie-Aline Charles [Full author list] | Metabolism [curation] | DOI: 10.1016/J.METABOL.2006.04.015
PubMed: 16919535 | lipoprotein [curation]; preproinsulin [curation]; HDL cholesterol [curation] | 2006-09-01 |
| Role of transcription factor NFAT in glucose and insulin homeostasis | [1]Teddy T C Yang, [2]Hee Yun Suk, [3]Xiaoyong Yang, [4]Opeyemi Olabisi, [5]Raymond Y L Yu, [6]Jorge Durand, [7]Linda A Jelicks, [8]Ja-Young Kim, [9]Philipp E. Scherer, [10]Yuhua Wang, [11]Yun Feng, [12]Luciano Rossetti, [13]Isabella A Graef, [14]Gerald R Crabtree, [15]Chi-Wing Chow [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.00580-06
PubMed: 16908540 | | 2006-08-14 |
| Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada | [1]Silvia Corvera, [2]Alison Burkart, [3]Ja-Young Kim, [4]Jennifer Christianson, [5]Zhao Wang, [6]Philipp E. Scherer [Full author list] | Genes & Development [curation] | DOI: 10.1101/GAD.1447506
PubMed: 16912272 | adipogenesis [curation] | 2006-08-01 |
| Adipose tissue: from lipid storage compartment to endocrine organ | [1]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DB06-0263
PubMed: 16731815 | | 2006-06-01 |
| Endothelin in a murine model of cerebral malaria. | [1]Fabiana S Machado, [2]Mahalia S Desruisseaux, [3]Nagajyothi, [4]Richard P Kennan, [5]Hoby P Hetherington, [6]Murray Wittner, [7]Louis M Weiss, [8]Sunhee C Lee, [9]Philipp E. Scherer, [10]Moriya Tsuji, [11]Herbert B Tanowitz [Full author list] | Experimental Biology and Medicine [curation] | PubMed: 16741072 | malaria [curation]; cerebral malaria [curation]; murine model [curation] | 2006-06-01 |
| MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness | [1]Chul-Hee Kim, [2]Patricia Pennisi, [3]Hong Zhao, [4]Shoshana Yakar, [5]Jeanne B Kaufman, [6]Kenjiro Iganaki, [7]Joseph Shiloach, [8]Philipp E. Scherer, [9]Michael J. Quon, [10]Derek LeRoith [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00319.2005
PubMed: 16507604 | insulin resistance [curation] | 2006-02-28 |
| ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity | [1]Nabila Bouatia-Naji, [2]David Meyre, [3]Stéphane Lobbens, [4]Karin Séron, [5]Frédéric Fumeron, [6]Beverley Balkau, [7]Barbara Heude, [8]Béatrice Jouret, [9]Philipp E. Scherer, [10]Christian Dina, [11]Jacques Weill, [12]Philippe Froguel [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.55.02.06.DB05-0971
PubMed: 16443793 | obesity [curation] | 2006-02-01 |
| Cyclin and caveolin expression in an acute model of murine Chagasic myocarditis. | [1]Fnu Nagajyothi, [2]Mahalia Desruisseaux, [3]Boumediene Bouzahzah, [4]Louis M Weiss, [5]Daniele dos Santos Andrade, [6]Stephen M Factor, [7]Philipp E. Scherer, [8]Chris Albanese, [9]Michael P. Lisanti, [10]Herbert B Tanowitz [Full author list] | Cell Cycle [curation] | DOI: 10.4161/CC.5.1.2284
PubMed: 16319533 | | 2006-01-28 |
| Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles | [1]Linglin Xie, [2]Daniel Boyle, [3]Daniel Sanford, [4]Philipp E. Scherer, [5]Jeffrey E Pessin, [6]Silvia Mora [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M511313200
PubMed: 16407204 | | 2005-12-29 |
| Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists | [1]Andrea R Nawrocki, [2]Michael W Rajala, [3]Eva Tomas, [4]Utpal B Pajvani, [5]Asish K Saha, [6]Myrna E Trumbauer, [7]Zhen Pang, [8]Airu S Chen, [9]Neil B Ruderman, [10]Howard Chen, [11]Luciano Rossetti, [12]Philipp E. Scherer [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M505311200
PubMed: 16326714 | preproinsulin [curation] | 2005-12-02 |
| Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice | [1]Ann V Hertzel, [2]Lisa Ann Smith, [3]Anders H Berg, [4]Gary W Cline, [5]Gerald I. Shulman, [6]Philipp E. Scherer, [7]David A Bernlohr [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00465.2005
PubMed: 16303844 | fatty acid [curation] | 2005-11-22 |
| Apoptosis through targeted activation of caspase 8 ("ATTAC-mice"): novel mouse models of inducible and reversible tissue ablation | [1]Maria E Trujillo, [2]Utpal B Pajvani, [3]Philipp E. Scherer [Full author list] | Cell Cycle [curation] | DOI: 10.4161/CC.4.9.2030
PubMed: 16096375 | | 2005-09-11 |
| Keynote review: the adipocyte as a drug discovery target | [1]Andrea R Nawrocki, [2]Philipp E. Scherer [Full author list] | Drug Discovery Today [curation] | DOI: 10.1016/S1359-6446(05)03569-5
PubMed: 16213414 | adipocyte [curation]; drug discovery [curation] | 2005-09-01 |
| Consuming fructose-sweetened beverages increases body adiposity in mice | [1]Hella Jürgens, [2]Wiltrud Haass, [3]Tamara R Castañeda, [4]Annette Schürmann, [5]Corinna Koebnick, [6]Frank Dombrowski, [7]Bärbel Otto, [8]Andrea R Nawrocki, [9]Philipp E. Scherer, [10]Jochen Spranger, [11]Michael Ristow, [12]Hans-Georg Joost, [13]Peter J Havel, [14]Matthias H Tschöp [Full author list] | Obesity [curation] | DOI: 10.1038/OBY.2005.136
PubMed: 16076983 | | 2005-07-01 |
| Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action | [1]Christophe Graveleau, [2]Vlad G Zaha, [3]Arash Mohajer, [4]Ronadip R Banerjee, [5]Nicole Dudley-Rucker, [6]Claire M Steppan, [7]Michael W Rajala, [8]Philipp E. Scherer, [9]Rexford S Ahima, [10]Mitchell A Lazar, [11]E. Dale Abel [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M504008200
PubMed: 15983036 | | 2005-06-27 |
| Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy | [1]Utpal B Pajvani, [2]Maria E Trujillo, [3]Terry P Combs, [4]Puneeth Iyengar, [5]Linda Jelicks, [6]Kevin A. Roth, [7]Richard N Kitsis, [8]Philipp E. Scherer [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM1262
PubMed: 15965483 | apoptotic process [curation] | 2005-06-19 |
| ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection | [1]Gloria Bonuccelli, [2]Federica Sotgia, [3]Philippe G. Frank, [4]Terence M Williams, [5]Cecilia J de Almeida, [6]Herbert B Tanowitz, [7]Philipp E. Scherer, [8]Kylie A Hotchkiss, [9]Bruce I Terman, [10]Brent Rollman, [11]Abdelkrim Alileche, [12]Jürgen Brojatsch, [13]Michael P. Lisanti [Full author list] | American Journal of Physiology - Cell Physiology [curation] | DOI: 10.1152/AJPCELL.00582.2004
PubMed: 15689409 | pathogenesis [curation]; Bacillus anthracis [curation] | 2005-06-01 |
| Adipose tissue, inflammation, and cardiovascular disease | [1]Anders H Berg, [2]Philipp E. Scherer [Full author list] | Circulation Research [curation] | DOI: 10.1161/01.RES.0000163635.62927.34
PubMed: 15890981 | cardiovascular disease [curation] | 2005-05-01 |
| Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats | [1]Hiroaki Satoh, [2]M T Audrey Nguyen, [3]Maria Trujillo, [4]Takeshi Imamura, [5]Isao Usui, [6]Philipp E. Scherer, [7]Jerrold M. Olefsky [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.54.5.1304
PubMed: 15855314 | Adenoviridae [curation]; preproinsulin [curation] | 2005-05-01 |
| The adipocyte as an important target cell for Trypanosoma cruzi infection | [1]Terry P Combs, [2]Nagajyothi, [3]Shankar Mukherjee, [4]Cecilia J G de Almeida, [5]Linda A Jelicks, [6]William Schubert, [7]Ying Lin, [8]David S Jayabalan, [9]Dazhi Zhao, [10]Vicki L Braunstein, [11]Shira Landskroner-Eiger, [12]Aisha Cordero, [13]Stephen M Factor, [14]Louis M Weiss, [15]Michael P. Lisanti, [16]Herbert B Tanowitz, [17]Philipp E. Scherer [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M412802200
PubMed: 15843370 | Trypanosoma cruzi [curation]; adipocyte [curation] | 2005-04-18 |
| Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment | [1]Puneeth Iyengar, [2]Virginia Espina, [3]Terence M Williams, [4]Ying Lin, [5]David Berry, [6]Linda A Jelicks, [7]Hyangkyu Lee, [8]Karla Temple, [9]Reed Graves, [10]Jeffrey W Pollard, ..., [21]Michael P. Lisanti, [22]Paolo Bonaldo, [23]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI23424
PubMed: 15841211 | adipocyte [curation]; tumor progression [curation] | 2005-04-14 |
| Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment | [1]Puneeth Iyengar, [2]Virginia Espina, [3]Terence M Williams, [4]Ying Lin, [5]David Berry, [6]Linda A Jelicks, [7]Hyangkyu Lee, [8]Karla Temple, [9]Reed Graves, [10]Jeffrey W Pollard, ..., [21]Michael P. Lisanti, [22]Paolo Bonaldo, [23]Philipp E. Scherer [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI200523424
| adipocyte [curation]; tumor progression [curation] | 2005-04-14 |
| Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue. | [1]Alex W Cohen, [2]William Schubert, [3]Dawn L Brasaemle, [4]Philipp E. Scherer, [5]Michael P. Lisanti [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.54.3.679
PubMed: 15734843 | thermogenesis [curation]; Caveolin 1 [curation]; Caveolin 1, caveolae protein [curation]; positive regulation of cold-induced thermogenesis [curation] | 2005-03-01 |
| Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle | [1]Franco Capozza, [2]Terry P Combs, [3]Alex W Cohen, [4]You-Ree Cho, [5]So-Young Park, [6]William Schubert, [7]Terence M Williams, [8]Dawn L Brasaemle, [9]Linda A Jelicks, [10]Philipp E. Scherer, [11]Jason K Kim, [12]Michael P. Lisanti [Full author list] | American Journal of Physiology - Cell Physiology [curation] | DOI: 10.1152/AJPCELL.00489.2004
PubMed: 15689413 | insulin resistance [curation]; knockout mouse [curation]; preproinsulin [curation] | 2005-02-02 |
| The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species | [1]Ying Lin, [2]Anders H Berg, [3]Puneeth Iyengar, [4]Tony K T Lam, [5]Adria Giacca, [6]Terry P Combs, [7]Michael W Rajala, [8]Xueliang Du, [9]Brent Rollman, [10]Weijie Li, [11]Meredith Hawkins, [12]Nir Barzilai, [13]Christopher J Rhodes, [14]I George Fantus, [15]Michael Brownlee, [16]Philipp E. Scherer [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M411863200
PubMed: 15536073 | inflammation [curation]; hyperglycemia [curation]; adipocyte [curation]; reactive oxygen species [curation] | 2004-11-09 |
| Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris). | [1]Gregory L Florant, [2]Heather Porst, [3]Aubrey Peiffer, [4]Susan F Hudachek, [5]Chris Pittman, [6]Scott A Summers, [7]Michael W Rajala, [8]Philipp E. Scherer [Full author list] | Journal of Comparative Physiology B [curation] | DOI: 10.1007/S00360-004-0454-0
PubMed: 15517283 | yellow-bellied marmot [curation]; weight gain [curation] | 2004-10-29 |
| Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion | [1]Terence M Williams, [2]Freddy A Medina, [3]Ines Badano, [4]Rachel B Hazan, [5]John Hutchinson, [6]William J Muller, [7]Neeru G Chopra, [8]Philipp E. Scherer, [9]Richard Pestell, [10]Michael P. Lisanti [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M409214200
PubMed: 15355971 | lung metastasis [curation]; neoplastic invasiveness [curation] | 2004-09-07 |
| Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development | [1]Ja-Young Kim, [2]Philipp E. Scherer [Full author list] | Pediatric Endocrinology Reviews [curation] | PubMed: 16444169 | adipocyte [curation] | 2004-08-01 |
| Optimization of protein production in mammalian cells with a coexpressed fluorescent marker | [1]Filippo Mancia, [2]Saurabh D Patel, [3]Michael W Rajala, [4]Philipp E. Scherer, [5]Adriana Nemes, [6]Ira Schieren, [7]Wayne A Hendrickson, [8]Lawrence Shapiro [Full author list] | Structure [curation] | DOI: 10.1016/J.STR.2004.06.012
PubMed: 15296729 | | 2004-08-01 |
| Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity | [1]Anders H Berg, [2]Ying Lin, [3]Michael P. Lisanti, [4]Philipp E. Scherer [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00002.2004
PubMed: 15251865 | adipocyte [curation]; NF-κB [curation] | 2004-07-13 |
| Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting | [1]Michael W Rajala, [2]Yong Qi, [3]Hiral R Patel, [4]Nobuhiko Takahashi, [5]Ronadip Banerjee, [6]Utpal B Pajvani, [7]Madhur K Sinha, [8]Ronald L Gingerich, [9]Philipp E. Scherer, [10]Rexford S Ahima [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.53.7.1671
PubMed: 15220189 | obesity [curation] | 2004-07-01 |
| Role of resistin in diet-induced hepatic insulin resistance | [1]Evan D Muse, [2]Silvana Obici, [3]Sanjay Bhanot, [4]Brett P Monia, [5]Robert A McKay, [6]Michael W Rajala, [7]Philipp E. Scherer, [8]Luciano Rossetti [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI200421270
PubMed: 15254590 | insulin resistance [curation]; preproinsulin [curation] | 2004-07-01 |
| The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation | [1]Andrea R Nawrocki, [2]Philipp E. Scherer [Full author list] | Current Opinion in Pharmacology [curation] | DOI: 10.1016/J.COPH.2004.03.003
PubMed: 15140421 | metabolic disease [curation] | 2004-06-01 |
| Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes | [1]Julia Tonelli, [2]Weijie Li, [3]Preeti Kishore, [4]Utpal B Pajvani, [5]Elize Kwon, [6]Charles Weaver, [7]Philipp E. Scherer, [8]Meredith Hawkins [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.53.6.1621
PubMed: 15161771 | type 2 diabetes [curation]; preproinsulin [curation] | 2004-06-01 |
| Disulfide-dependent multimeric assembly of resistin family hormones | [1]Saurabh D Patel, [2]Michael W Rajala, [3]Luciano Rossetti, [4]Philipp E. Scherer, [5]Lawrence Shapiro [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.1093466
PubMed: 15155948 | | 2004-05-01 |
| Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation | [1]Alex W Cohen, [2]Babak Razani, [3]William Schubert, [4]Terence M Williams, [5]Xiao Bo Wang, [6]Puneeth Iyengar, [7]Dawn L Brasaemle, [8]Philipp E. Scherer, [9]Michael P. Lisanti [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.53.5.1261
PubMed: 15111495 | | 2004-05-01 |
| Adiponectin acts in the brain to decrease body weight | [1]Yong Qi, [2]Nobuhiko Takahashi, [3]Stanley M Hileman, [4]Hiralben R Patel, [5]Anders H Berg, [6]Utpal B Pajvani, [7]Philipp E. Scherer, [8]Rexford S Ahima [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM1029
PubMed: 15077108 | | 2004-04-11 |
| Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia | [1]Terence M Williams, [2]Hyangkyu Lee, [3]Michelle Cheung, [4]Alex W Cohen, [5]Babak Razani, [6]Puneeth Iyengar, [7]Philipp E. Scherer, [8]Richard Pestell, [9]Michael P. Lisanti [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M402064200
PubMed: 15044451 | | 2004-03-25 |
| Evidence for enhanced adipogenesis in the orbits of patients with Graves' ophthalmopathy | [1]Seema Kumar, [2]Michael J Coenen, [3]Philipp E. Scherer, [4]Rebecca S Bahn [Full author list] | The Journal of Clinical Endocrinology and Metabolism [curation] | DOI: 10.1210/JC.2003-031427
PubMed: 14764816 | patient [curation]; adipogenesis [curation] | 2004-02-01 |
| Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity | [1]Utpal B Pajvani, [2]Meredith Hawkins, [3]Terry P Combs, [4]Michael W Rajala, [5]Tom Doebber, [6]Joel P Berger, [7]John A Wagner, [8]Margaret Wu, [9]Annemie Knopps, [10]Anny H Xiang, [11]Kristina M Utzschneider, [12]Steven E. Kahn, [13]Jerrold M. Olefsky, [14]Thomas A Buchanan, [15]Philipp E. Scherer [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M311113200
PubMed: 14699128 | preproinsulin [curation] | 2003-12-29 |
| Role of caveolin and caveolae in insulin signaling and diabetes | [1]Alex W. Cohen, [2]Terry P. Combs, [3]Philipp E. Scherer, [4]Michael P. Lisanti [Full author list] | American Journal of Physiology - Endocrinology and Metabolism [curation] | DOI: 10.1152/AJPENDO.00324.2003
PubMed: 14607781 | physiology [curation]; signal transduction [curation]; preproinsulin [curation] | 2003-12-01 |
| Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases | [1]Federica Sotgia, [2]Gloria Bonuccelli, [3]Carlo Minetti, [4]Scott E Woodman, [5]Franco Capozza, [6]Robert G Kemp, [7]Philipp E. Scherer, [8]Michael P. Lisanti [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/S0002-9440(10)63616-4
PubMed: 14633633 | pathogenesis [curation] | 2003-12-01 |
| A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity | [1]Terry P Combs, [2]Utpal B Pajvani, [3]Anders H Berg, [4]Ying Lin, [5]Linda A Jelicks, [6]Mathieu Laplante, [7]Andrea R Nawrocki, [8]Michael W Rajala, [9]Albert F Parlow, [10]Laurelle Cheeseboro, [11]Yang-Yang Ding, [12]Robert G Russell, [13]Dirk Lindemann, [14]Adam Hartley, [15]Glynn R C Baker, [16]Silvana Obici, [17]Yves Deshaies, [18]Marian Ludgate, [19]Luciano Rossetti, [20]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2003-1068
PubMed: 14576179 | preproinsulin [curation] | 2003-10-23 |
| Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization | [1]Puneeth Iyengar, [2]Terry P. Combs, [3]Shalin J. Shah, [4]Valérie Gouon-Evans, [5]Jeffrey W Pollard, [6]Chris Albanese, [7]Louise Flanagan, [8]Martin P. Tenniswood, [9]Chandan Guha, [10]Michael P. Lisanti, [11]Richard G. Pestell, [11-Q7328381]Richard Pestell, [12]Philipp E. Scherer [Full author list] | Oncogene [curation] | DOI: 10.1038/SJ.ONC.1206737
PubMed: 14508521 | genetics [curation]; transcription [curation]; adipocyte [curation]; apoptotic process [curation] | 2003-09-25 |
| Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation | [1]Chenguang Wang, [2]Nagarajan Pattabiraman, [3]Jian Nian Zhou, [4]Maofu Fu, [5]Toshiyuki Sakamaki, [6]Chris Albanese, [7]Zhiping Li, [8]Kongming Wu, [9]James Hulit, [10]Peter Neumeister, [11]Phyllis M Novikoff, [12]Michael Brownlee, [13]Philipp E. Scherer, [14]Joan G Jones, [15]Kathleen D Whitney, [16]Lawrence A Donehower, [17]Emily L Harris, [18]Thomas Rohan, [19]David C Johns, [20]Richard Pestell [Full author list] | Molecular and Cellular Biology [curation] | DOI: 10.1128/MCB.23.17.6159-6173.2003
PubMed: 12917338 | cell biology [curation] | 2003-09-01 |
| Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis | [1]Michael W Rajala, [2]Philipp E. Scherer [Full author list] | Endocrinology [curation] | DOI: 10.1210/EN.2003-0580
PubMed: 12933646 | adipocyte [curation]; atherosclerosis [curation] | 2003-09-01 |
| Phenotypic behavior of caveolin-3 R26Q, a mutant associated with hyperCKemia, distal myopathy, and rippling muscle disease | [1]Federica Sotgia, [2]Scott E Woodman, [3]Gloria Bonuccelli, [4]Franco Capozza, [5]Carlo Minetti, [6]Philipp E. Scherer, [7]Michael P. Lisanti [Full author list] | American Journal of Physiology - Cell Physiology [curation] | DOI: 10.1152/AJPCELL.00166.2003
PubMed: 12839838 | distal muscular dystrophy [curation] | 2003-07-02 |
| Adiponectin: systemic contributor to insulin sensitivity | [1]Utpal B Pajvani, [2]Philipp E. Scherer [Full author list] | Current diabetes report [curation] | DOI: 10.1007/S11892-003-0065-2
PubMed: 12762967 | preproinsulin [curation] | 2003-06-01 |
| Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue | [1]Alex W Cohen, [2]Babak Razani, [3]Xiao Bo Wang, [4]Terry P Combs, [5]Terence M Williams, [6]Philipp E. Scherer, [7]Michael P. Lisanti [Full author list] | American Journal of Physiology - Cell Physiology [curation] | DOI: 10.1152/AJPCELL.00006.2003
PubMed: 12660144 | insulin resistance [curation]; preproinsulin [curation] | 2003-03-26 |
| Adiponectin/Acrp30, an adipocyte-specific secretory factor: physiological relevance during development | [1]Puneeth Iyengar, [2]Philipp E. Scherer [Full author list] | Pediatric Diabetes [curation] | DOI: 10.1034/J.1399-5448.2003.00029.X
PubMed: 14655522 | adipocyte [curation] | 2003-03-01 |
| Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin | [1]Terry P Combs, [2]Anders H Berg, [3]Michael W Rajala, [4]Simon Klebanov, [5]Puneeth Iyengar, [6]José C Jimenez-Chillaron, [7]Mary Elizabeth Patti, [8]Sabra Klein, [9]Robert S Weinstein, [10]Philipp E. Scherer [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.52.2.268
PubMed: 12540596 | adipocyte [curation]; calorie restriction [curation] | 2003-02-01 |
| Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production | [1]Michael W Rajala, [2]Silvana Obici, [3]Philipp E. Scherer, [4]Luciano Rossetti [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI16521
PubMed: 12531878 | glucose [curation]; glycobiology [curation]; preproinsulin [curation] | 2003-01-01 |
| Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity | [1]Utpal B Pajvani, [2]Xueliang Du, [3]Terry P Combs, [4]Anders H Berg, [5]Michael W Rajala, [6]Therese Schulthess, [7]Jürgen Engel, [8]Michael Brownlee, [9]Philipp E. Scherer [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M207198200
PubMed: 12496257 | adipocyte [curation] | 2002-12-20 |
| Adiponectin and leptin levels in HIV-infected subjects with insulin resistance and body fat redistribution | [1]Dennis C Mynarcik, [2]Terry Combs, [3]Margaret A McNurlan, [4]Philipp E. Scherer, [5]Eugene Komaroff, [6]Marie C Gelato [Full author list] | Journal of Acquired Immune Deficiency Syndromes [curation] | DOI: 10.1097/00126334-200212150-00009
PubMed: 12473840 | insulin resistance [curation]; preproinsulin [curation] | 2002-12-01 |
| A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation | [1]Romel Somwar, [2]Sandra Koterski, [3]Gary Sweeney, [4]Richard Sciotti, [5]Stevan Djuric, [6]Cathy Berg, [7]James Trevillyan, [8]Philipp E. Scherer, [9]Christina M Rondinone, [10]Amira Klip [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M205277200
PubMed: 12393894 | adipocyte [curation]; preproinsulin [curation] | 2002-10-21 |
| Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1 | [1]Hyangkyu Lee, [2]David S Park, [3]Xiao Bo Wang, [4]Philipp E. Scherer, [5]Phillip E Schwartz, [6]Michael P. Lisanti [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M204367200
PubMed: 12091389 | molecular mass [curation]; phosphorylation [curation]; membrane raft [curation]; Caveolin 2 [curation]; Caveolin 1 [curation]; Caveolin 1, caveolae protein [curation]; Caveolin 2 [curation]; Rous sarcoma oncogene [curation]; Non-catalytic region of tyrosine kinase adaptor protein 2 [curation] | 2002-09-13 |
| Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue | [1]Michael W Rajala, [2]Ying Lin, [3]Mollie Ranalletta, [4]Xiao Man Yang, [5]Hao Qian, [6]Ron Gingerich, [7]Nir Barzilai, [8]Philipp E. Scherer [Full author list] | Molecular Endocrinology [curation] | DOI: 10.1210/ME.2002-0048
PubMed: 12145345 | | 2002-08-01 |
| A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome | [1]Claudia Menzaghi, [2]Tonino Ercolino, [3]Rosa Di Paola, [4]Anders H Berg, [5]James H Warram, [6]Philipp E. Scherer, [7]Vincenzo Trischitta, [8]Alessandro Doria [Full author list] | Diabetes [curation] | DOI: 10.2337/DIABETES.51.7.2306
PubMed: 12086965 | obesity [curation]; insulin resistance [curation]; preproinsulin [curation] | 2002-07-01 |
| Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis | [1]Babak Razani, [2]David S Park, [3]Yuko Miyanaga, [4]Ashwini Ghatpande, [5]Justin Cohen, [6]Xiao Bo Wang, [7]Philipp E. Scherer, [8]Todd Evans, [9]Michael P. Lisanti [Full author list] | Biochemistry [curation] | DOI: 10.1021/BI020043N
PubMed: 12069580 | African clawed frog [curation] | 2002-06-01 |
| ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism | [1]Anders H Berg, [2]Terry P Combs, [3]Philipp E. Scherer [Full author list] | Trends in Endocrinology and Metabolism [curation] | DOI: 10.1016/S1043-2760(01)00524-0
PubMed: 11854024 | glucose [curation] | 2002-03-01 |
| A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes | [1]Irina Kratchmarova, [2]Dario E Kalume, [3]Blagoy Blagoev, [4]Philipp E. Scherer, [5]Alexandre Podtelejnikov, [6]Henrik Molina, [7]Perry E Bickel, [8]Jens S Andersen, [9]Minerva M Fernandez, [10]Jacob Bunkenborg, [11]Peter Roepstorff, [12]Karsten Kristiansen, [13]Harvey Lodish, [14]Matthias Mann, [15]Akhilesh Pandey [Full author list] | Molecular & Cellular Proteomics [curation] | DOI: 10.1074/MCP.M200006-MCP200
PubMed: 12096121 | adipocyte [curation] | 2002-03-01 |
| Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization | [1]Terry P Combs, [2]John A Wagner, [3]Joel Berger, [4]Tom Doebber, [5]Wen-Jun Wang, [6]Bei B Zhang, [7]Michael Tanen, [8]Anders H Berg, [9]Stephen O'Rahilly, [10]David B Savage, [11]Krishna Chatterjee, [12]Stuart Weiss, [13]Patrick J Larson, [14]Keith M Gottesdiener, [15]Barry J Gertz, [16]Maureen J Charron, [17]Philipp E. Scherer, [18]David E Moller [Full author list] | Endocrinology [curation] | DOI: 10.1210/ENDO.143.3.8662
PubMed: 11861525 | adipocyte [curation]; preproinsulin [curation] | 2002-03-01 |
| Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities | [1]Babak Razani, [2]Terry P Combs, [3]Xiao Bo Wang, [4]Philippe G. Frank, [5]David S Park, [6]Robert G Russell, [7]Maomi Li, [8]Baiyu Tang, [9]Linda A Jelicks, [10]Philipp E. Scherer, [11]Michael P. Lisanti [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M110970200
PubMed: 11739396 | obesity [curation]; adipocyte [curation]; hypertriglyceridemia [curation] | 2001-12-05 |
| Constitutive and Growth Factor-Regulated Phosphorylation of Caveolin-1 Occurs at the Same Site (Tyr-14)in Vivo:Identification of a c-Src/Cav-1/Grb7 Signaling Cassette | [1]H Lee, [1-Q85711321]Hyangkyu Lee, [2]D Volonte, [3]F Galbiati, [4]P Iyengar, [5]D M Lublin, [6]David B. Bregman, [7]M T Wilson, [8]R Campos-Gonzalez, [9]B Bouzahzah, [10]R G Pestell, [10-Q60572448]Philipp E. Scherer, [11]Michael P. Lisanti, [11-Q92504491]Michael P Lisanti, [12]M P Lisanti, [3-Q117233025]Ferruccio Galbiati, [4-Q117233026]Puneeth Iyengar, [9-Q7328381]Richard Pestell [Full author list] | Molecular Endocrinology [curation] | DOI: 10.1210/MEND.14.11.0553
PubMed: 11075810 | phosphorylation [curation]; Growth factor receptor bound protein 7 [curation] | 2000-11-01 |