| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form | [1]Micah T Nelp, [2]Patrick A Kates, [3]J T Hunt, [4]John A Newitt, [5]Aaron Balog, [6]Derrick Maley, [7]Xiao Zhu, [8]Lynn Abell, [9]Alban Allentoff, [10]Robert Borzilleri, [11]Hal A Lewis, [12]Zeyu Lin, [13]Steven P Seitz, [14]Chunhong Yan, [15]John T. Groves [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1719190115
PubMed: 29531094 | | 2018-03-12 |
| Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. | [1]David K Williams, [2]Jay A Markwalder, [3]Aaron Balog, [4]Bin Chen, [5]Libing Chen, [6]Jennifer Donnell, [7]Lauren Haque, [8]Amy C. Hart, [9]Sunil K Mandal, [10]Andrew Nation, [11]Weifang Shan, [12]Gregory D Vite, [13]Kelly Covello, [14]J T Hunt, [15]Maria N Jure-Kunkel, [16]Steven P Seitz [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2018.01.010
PubMed: 29398543 | | 2018-01-11 |
| Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors | [1]Jay A Markwalder, [2]Steven P Seitz, [3]Yuval Blat, [4]Lisa Elkin, [5]J T Hunt, [6]Jonathan G Pabalan, [7]Maria N Jure-Kunkel, [8]Gregory D Vite, [9]Kelly Covello [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2016.12.015
PubMed: 28003141 | | 2016-12-07 |
| Correction to N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent | [1]Raj N Misra, [2]Hai-yun Xiao, [3]Kyoung S Kim, [4]Songfeng Lu, [5]Wen-Ching Han, [6]Stephanie A Barbosa, [7]J T Hunt, [8]David B Rawlins, [9]Weifang Shan, [10]Syed Z Ahmed, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/ACS.JMEDCHEM.5B01294
PubMed: 26328598 | sns-032 [curation] | 2015-09-02 |
| Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport | [1]Randy L Talbott, [2]Robert M Borzilleri, [3]Charu Chaudhry, [4]Joseph Fargnoli, [5]Henry Shen, [6]Craig Fairchild, [7]Bryan Barnhart, [8]Marie Ortega, [9]Thomas E McDonagh, [10]Ragini Vuppugalla, [11]Gregory D Vite, [12]J T Hunt, [13]Marco Gottardis, [14]Joseph G Naglich [Full author list] | Experimental Cell Research [curation] | DOI: 10.1016/J.YEXCR.2015.08.011
PubMed: 26302264 | chemotype [curation] | 2015-08-21 |
| BMS-871: a novel orally active pan-Notch inhibitor as an anticancer agent | [1]Weifang Shan, [2]Aaron Balog, [3]Claude Quesnelle, [4]Patrice Gill, [5]Wen-Ching Han, [6]Derek Norris, [7]Sunilkumar Mandal, [8]Raja Thiruvenkadam, [9]Kiran Babu Gona, [10]Kamalraj Thiyagarajan, ..., [25]Richard Rampulla, [26]George Trainor, [27]J T Hunt, [28]Gregory D Vite, [29]Richard Westhouse, ... [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2015.03.038
PubMed: 25857941 | | 2015-03-23 |
| Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors | [1]Ashvinikumar V Gavai, [2]Claude Quesnelle, [3]Derek Norris, [4]Wen-Ching Han, [5]Patrice Gill, [6]Weifang Shan, [7]Aaron Balog, [8]Ke Chen, [9]Andrew Tebben, [10]Richard Rampulla, ..., [32]Richard Olson, [33]Phil S Baran, [34]J T Hunt, [35]Gregory D Vite, [36]Bruce S Fischer, ... [Full author list] | ACS Medicinal Chemistry Letters [curation] | DOI: 10.1021/ACSMEDCHEMLETT.5B00001
PubMed: 26005526 | | 2015-03-11 |
| Antitumor and antiangiogenic activities of BMS-690514, an inhibitor of human EGF and VEGF receptor kinase families | [1]Tai W Wong, [2]Francis Y Lee, [3]Stuart Emanuel, [4]Craig Fairchild, [5]Joseph Fargnoli, [6]Brian Fink, [7]Ashvinikumar Gavai, [8]Amy Hammell, [9]Benjamin Henley, [10]Christine Hilt, [11]J T Hunt, [12]Bala Krishnan, [13]Daniel Kukral, [14]Anne Lewin, [15]Harold Malone, [16]Derek Norris, [17]Simone Oppenheimer, [18]Gregory Vite, [19]Chiang Yu [Full author list] | Clinical Cancer Research [curation] | DOI: 10.1158/1078-0432.CCR-10-3417
PubMed: 21531814 | angiogenesis inhibitor [curation] | 2011-04-29 |
| The antiangiogenic activity in xenograft models of brivanib, a dual inhibitor of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinases | [1]Rajeev S Bhide, [2]Louis J Lombardo, [3]J T Hunt, [4]Zhen-Wei Cai, [5]Joel C Barrish, [6]Susan Galbraith, [7]Robert Jeyaseelan, [8]Steven Mortillo, [9]Barri S Wautlet, [10]Bala Krishnan, [11]Daniel Kukral, [12]Harold Malone, [13]Anne C Lewin, [14]Benjamin J Henley, [15]Joseph Fargnoli [Full author list] | Molecular Cancer Therapeutics [curation] | DOI: 10.1158/1535-7163.MCT-09-0472
PubMed: 20103604 | endothelium [curation]; angiogenesis inhibitor [curation]; xenograft [curation] | 2010-01-26 |
| Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily | [1]Gretchen M Schroeder, [2]Yongmi An, [3]Zhen-Wei Cai, [4]Xiao-Tao Chen, [5]Cheryl Clark, [6]Lyndon A M Cornelius, [7]Jun Dai, [8]Johnni Gullo-Brown, [9]Ashok Gupta, [10]Benjamin Henley, [11]J T Hunt, [12]Robert Jeyaseelan, [13]Amrita Kamath, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM801586S
PubMed: 19260711 | | 2009-03-01 |
| Discovery of ixabepilone | [1]John T Hunt, [1-Q67487747]J T Hunt [Full author list] | Molecular Cancer Therapeutics [curation] | DOI: 10.1158/1535-7163.MCT-08-0999
PubMed: 19174552 | | 2009-01-27 |
| Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor | [1]Réjean Ruel, [2]Carl Thibeault, [3]Alexandre L'Heureux, [4]Alain Martel, [5]Zhen-Wei Cai, [6]Donna Wei, [7]Ligang Qian, [8]Joel C Barrish, [9]Arvind Mathur, [10]Celia D'Arienzo, [11]J T Hunt, [12]Amrita Kamath, [13]Punit Marathe, ... [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2008.03.057
PubMed: 18395443 | | 2008-03-22 |
| Discovery of brivanib alaninate ((S)-((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), a novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor (BMS-540215) | [1]Zhen-wei Cai, [2]Yongzheng Zhang, [3]Robert M Borzilleri, [4]Ligang Qian, [5]Stephanie Barbosa, [6]Donna Wei, [7]Xiaoping Zheng, [8]Lawrence Wu, [9]Junying Fan, [10]Zhongping Shi, ..., [19]Joel C Barrish, [20]Jeffrey A Robl, [21]J T Hunt, [22]Louis J Lombardo, [23]Joseph Fargnoli, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM7013309
PubMed: 18288793 | endothelium [curation] | 2008-02-21 |
| Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinase | [1]Gretchen M Schroeder, [2]Xiao-Tao Chen, [3]David K Williams, [4]David S. Nirschl, [5]Zhen-Wei Cai, [6]Donna Wei, [7]John S Tokarski, [8]Yongmi An, [9]John Sack, [10]Zhong Chen, ..., [16]Kristen Kellar, [17]Veeraswamy Manne, [18]J T Hunt, [19]Tai W Wong, [20]Louis J Lombardo, ... [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2008.01.121
PubMed: 18289854 | | 2008-02-07 |
| Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1-f][1,2,4]triazine-based VEGFR-2 kinase inhibitors | [1]Zhen-Wei Cai, [2]Donna Wei, [3]Robert M Borzilleri, [4]Ligang Qian, [5]Amrita Kamath, [6]Steven Mortillo, [7]Barri Wautlet, [8]Benjamin J Henley, [9]Robert Jeyaseelan, [10]John Tokarski, [11]J T Hunt, [12]Rajeev S Bhide, [13]Joseph Fargnoli, [14]Louis J Lombardo [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2008.01.012
PubMed: 18221875 | | 2008-01-09 |
| Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling | [1]Tai W Wong, [2]Francis Y Lee, [3]Chiang Yu, [4]Feng R Luo, [5]Simone Oppenheimer, [6]Hongjian Zhang, [7]Richard A Smykla, [8]Harold Mastalerz, [9]Brian E Fink, [10]J T Hunt, [11]Ashvinikumar V Gavai, [12]Gregory D Vite [Full author list] | Clinical Cancer Research [curation] | DOI: 10.1158/1078-0432.CCR-06-0642
PubMed: 17062696 | | 2006-10-01 |
| Discovery and evaluation of N-cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2 | [1]Robert M Borzilleri, [2]Rajeev S Bhide, [3]Joel C Barrish, [4]Celia J D'Arienzo, [5]George M Derbin, [6]Joseph Fargnoli, [7]J T Hunt, [8]Robert Jeyaseelan, [9]Amrita Kamath, [10]Daniel W Kukral, [11]Punit Marathe, [12]Steve Mortillo, [13]Ligang Qian, [14]John S Tokarski, [15]Barri S Wautlet, [16]Xiaoping Zheng, [17]Louis J Lombardo [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM060347Y
PubMed: 16789733 | | 2006-06-01 |
| Discovery and preclinical studies of (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an in vivo active potent VEGFR-2 inhibitor | [1]Rajeev S Bhide, [2]Zhen-Wei Cai, [3]Yong-Zheng Zhang, [4]Ligang Qian, [5]Donna Wei, [6]Stephanie Barbosa, [7]Louis J Lombardo, [8]Robert M Borzilleri, [9]Xiaoping Zheng, [10]Laurence I Wu, ..., [19]Robert Jeyaseelan, [20]Daniel Kukral, [21]J T Hunt, [22]Amrita Kamath, [23]Aberra Fura, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM051106D
PubMed: 16570908 | | 2006-04-01 |
| New dual inhibitors of EGFR and HER2 protein tyrosine kinases | [1]Brian E Fink, [2]Gregory D Vite, [3]Harold Mastalerz, [4]John F Kadow, [5]Soong-Hoon Kim, [6]Kenneth J Leavitt, [7]Karen Du, [8]Donald Crews, [9]Toomas Mitt, [10]Tai W Wong, [11]J T Hunt, [12]Dolatrai M Vyas, [13]John S Tokarski [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2005.07.027
PubMed: 16111887 | | 2005-11-01 |
| Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors | [1]Robert M Borzilleri, [2]Xiaoping Zheng, [3]Ligang Qian, [4]C D Ellis, [5]Zhen-wei Cai, [6]Barri S Wautlet, [7]Steve Mortillo, [8]Robert Jeyaseelan, [9]Daniel W Kukral, [10]Aberra Fura, [11]Amrita Kamath, [12]Viral Vyas, [13]John S Tokarski, [14]Joel C Barrish, [15]J T Hunt, [16]Louis J Lombardo, [17]Joseph Fargnoli, [18]Rajeev S Bhide [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM0501275
PubMed: 15943473 | | 2005-06-01 |
| Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors | [1]Louis J Lombardo, [2]Amy Camuso, [3]John Clark, [4]Krista Fager, [5]Johnni Gullo-Brown, [6]J T Hunt, [7]Ivan Inigo, [8]David Kan, [9]Barry Koplowitz, [10]Francis Lee, ... [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2005.02.004
PubMed: 15780629 | | 2005-04-01 |
| Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1-f][1,2,4]triazine based VEGFR-2 kinase inhibitors | [1]Robert M Borzilleri, [2]Zhen-Wei Cai, [3]C D Ellis, [4]Joseph Fargnoli, [5]Aberra Fura, [6]Tracy Gerhardt, [7]Bindu Goyal, [8]J T Hunt, [9]Steven Mortillo, [10]Ligang Qian, [11]John Tokarski, [12]Viral Vyas, [13]Barri Wautlet, [14]Xioping Zheng, [15]Rajeev S Bhide [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2004.12.079
PubMed: 15713401 | | 2005-03-01 |
| Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus | [1]Mark E Salvati, [2]Aaron Balog, [3]Donna D Wei, [4]Dacia Pickering, [5]Ricardo M Attar, [6]Jieping Geng, [7]Cheryl A Rizzo, [8]J T Hunt, [9]Marco M Gottardis, [10]Roberto Weinmann, [11]Rogelio Martinez [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/J.BMCL.2004.10.051
PubMed: 15603960 | | 2005-01-01 |
| Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays | [1]Louis J Lombardo, [2]Francis Y Lee, [3]Ping Chen, [4]Derek Norris, [5]Joel C Barrish, [6]Kamelia Behnia, [7]Stephen Castaneda, [8]Lyndon A M Cornelius, [9]Jagabandhu Das, [10]Arthur M Doweyko, [11]Craig Fairchild, [12]J T Hunt, [13]Ivan Inigo, [14]Kathy Johnston, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM049486A
PubMed: 15615512 | dasatinib [curation] | 2004-12-01 |
| Discovery of the pyrrolo[2,1-f][1,2,4]triazine nucleus as a new kinase inhibitor template | [1]J T Hunt, [2]Toomas Mitt, [3]Robert Borzilleri, [4]Johnni Gullo-Brown, [5]Joseph Fargnoli, [6]Brian Fink, [7]Wen-Ching Han, [8]Steven Mortillo, [9]Gregory Vite, [10]Barri Wautlet, [11]Tai Wong, [12]Chiang Yu, [13]Xiaoping Zheng, [14]Rajeev Bhide [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM049892U
PubMed: 15267243 | | 2004-07-01 |
| Apoptotic and cytostatic farnesyltransferase inhibitors have distinct pharmacology and efficacy profiles in tumor models | [1]Veeraswamy Manne, [2]Francis Y F Lee, [3]David K Bol, [4]Johnni Gullo-Brown, [5]Craig R Fairchild, [6]Louis J Lombardo, [7]Richard A Smykla, [8]Gregory D Vite, [9]Mei-Li D Wen, [10]Chiang Yu, [11]Tai Wai Wong, [12]J T Hunt [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-03-3849
PubMed: 15173010 | apoptotic process [curation] | 2004-06-01 |
| Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects | [1]K S Kim, [2]J S Sack, [3]J S Tokarski, [4]L Qian, [5]S T Chao, [6]L Leith, [7]Y F Kelly, [8]R N Misra, [9]J T Hunt, [10]S D Kimball, [11]W G Humphreys, [12]B S Wautlet, [13]J G Mulheron, [14]K R Webster [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM000231G
PubMed: 11063609 | | 2000-11-01 |
| 3-Imidazolylmethylaminophenylsulfonyltetrahydroquinolines, a novel series of farnesyltransferase inhibitors | [1]C Z Ding, [2]J T Hunt, [3]C Ricca, [4]Veeraswamy Manne [Full author list] | Bioorganic & Medicinal Chemistry Letters [curation] | DOI: 10.1016/S0960-894X(99)00686-1
PubMed: 10698452 | | 2000-02-01 |
| Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308) | [1]N Murugesan, [2]Z Gu, [3]P D Stein, [4]S Bisaha, [5]S Spergel, [6]R Girotra, [7]V G Lee, [8]J Lloyd, [9]R N Misra, [10]J Schmidt, ..., [23]A A Seymour, [24]M L Webb, [25]J T Hunt [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM970872K
PubMed: 9857090 | | 1998-12-01 |
| Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity | [1]Leftheris K, [2]Kline T, [3]Vite GD, [4]Cho YH, [5]Bhide RS, [6]Patel DV, [7]Patel MM, [8]Schmidt RJ, [9]Weller HN, [10]Andahazy ML, ..., [16]Yan N, [17]Barbacid M, [18]J T Hunt, [19]Meyers CA, [20]Seizinger BR, ... [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM950642A
PubMed: 8568812 | | 1996-01-01 |
| Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase | [1]J T Hunt, [2]Lee VG, [3]Leftheris K, [4]Seizinger B, [5]Carboni J, [6]Mabus J, [7]Ricca C, [8]Yan N, [9]Veeraswamy Manne [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM9507284
PubMed: 8558502 | | 1996-01-01 |
| Endothelin analogs which distinguish vasoconstrictor and vasodilator ETB receptors | [1]S Natarajan, [2]J T Hunt, [3]S Festin, [4]R Serafino, [5]R Zhang, [6]S Moreland [Full author list] | Life Sciences [curation] | DOI: 10.1016/S0024-3205(95)00070-4
PubMed: 8614242 | | 1995-03-01 |
| The receptor binding affinity of monocyclic [Ala3,Xaa11]endothelin-1 analogs correlates with inducible helix length | [1]N H Andersen, [2]S M Harris, [3]V G Lee, [4]E C Liu, [5]S Moreland, [6]J T Hunt [Full author list] | Bioorganic & Medicinal Chemistry [curation] | DOI: 10.1016/0968-0896(95)00005-2
PubMed: 7796045 | | 1995-02-01 |
| Three-dimensional quantitative structure-activity relationships of sulfonamide endothelin inhibitors | [1]S R Krystek, [2]J T Hunt, [3]P D Stein, [4]T R Stouch [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM00004A012
PubMed: 7861414 | | 1995-02-01 |
| The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide | [1]P D Stein, [2]J T Hunt, [3]D M Floyd, [4]S Moreland, [5]K E Dickinson, [6]C Mitchell, [7]E C Liu, [8]M L Webb, [9]N Murugesan, [10]J Dickey [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM00029A001
PubMed: 8308857 | | 1994-02-01 |
| Structure-activity studies of endothelin leading to novel peptide ETA antagonists | [1]J T Hunt, [2]V G Lee, [3]D McMullen, [4]E C Liu, [5]M Bolgar, [6]C L Delaney, [7]S M Festin, [8]D M Floyd, [9]A Hedberg, [10]S Natarajan [Full author list] | Bioorganic & Medicinal Chemistry [curation] | DOI: 10.1016/S0968-0896(00)82103-3
PubMed: 8081838 | | 1993-07-01 |
| Peptide analogs of the pseudosubstrate domain of smooth muscle myosin light chain kinase inhibit actomyosin ATPase activity at concentrations that do not inhibit superprecipitation | [1]S. Moreland, [2]M. Ikebe, [3]J T Hunt, [4]R. S. Moreland [Full author list] | Biochemical and Biophysical Research Communications [curation] | DOI: 10.1016/0006-291X(92)90441-M
PubMed: 1417804 | | 1992-09-30 |
| Substrate based inhibitors of smooth muscle myosin light chain kinase | [1]S Moreland, [2]M Ikebe, [3]J T Hunt, [4]R S Moreland [Full author list] | Biochemical and Biophysical Research Communications [curation] | DOI: 10.1016/S0006-291X(05)80996-9
PubMed: 1599475 | | 1992-05-01 |
| Venous smooth muscle contains vasoconstrictor ETB-like receptors | [1]S Moreland, [2]D M McMullen, [3]C L Delaney, [4]V G Lee, [5]J T Hunt [Full author list] | Biochemical and Biophysical Research Communications [curation] | DOI: 10.1016/0006-291X(92)91163-K
PubMed: 1314581 | | 1992-04-01 |
| Solution conformation of a cyclic pentapeptide endothelin antagonist. Comparison of structures obtained from constrained dynamics and conformational search | [1]S. R. Krystek, [2]D. A. Bassolino, [3]Robert E. Bruccoleri, [4]J T Hunt, [5]M. A. Porubcan, [6]C. F. Wandler, [7]N. H. Andersen [Full author list] | FEBS Letters [curation] | DOI: 10.1016/0014-5793(92)80127-3
PubMed: 1544503 | | 1992-03-16 |
| Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site | [1]S. D. Kimball, [2]D. M. Floyd, [3]J. Das, [4]J T Hunt, [5]J. Krapcho, [6]G. Rovnyak, [7]K. J. Duff, [8]V. G. Lee, [9]R. V. Moquin, [10]C. F. Turk [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM00082A020
PubMed: 1311765 | | 1992-02-21 |
| Multiple pathways of thrombin-induced platelet activation differentiated by desensitization and a thrombin exosite inhibitor | [1]S M Seiler, [2]H J Goldenberg, [3]I M Michel, [4]J T Hunt, [5]G B Zavoico [Full author list] | Biochemical and Biophysical Research Communications [curation] | DOI: 10.1016/0006-291X(91)91238-8
PubMed: 1755847 | desensitization [curation] | 1991-12-01 |
| Hydroxyamino acid specificity of smooth muscle myosin light chain kinase | [1]Rick Pearson, [2]D M Floyd, [3]J T Hunt, [4]V G Lee, [5]B E Kemp [Full author list] | Archives of Biochemistry and Biophysics [curation] | DOI: 10.1016/0003-9861(88)90421-3
PubMed: 3341750 | | 1988-01-01 |