| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Sarcoma classification by DNA methylation profiling | [1]Christian Koelsche, [2]Daniel Schrimpf, [3]Damian Stichel, [4]Martin Sill, [5]Felix Sahm, [6]David E Reuss, [7]Mirjam Blattner, [8]Barbara C Worst, [9]Christoph E Heilig, [10]Katja Beck, ..., [33]Till Milde, [34]Olaf Witt, [35]Andreas E Kulozik, [36]Marcel Kool, [37]Laura Romero-Pérez, ... [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-020-20603-4
PubMed: 33479225 | | 2021-01-21 |
| Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors | [1]Büşra Erarslan-Uysal, [2]Joachim B Kunz, [3]Tobias Rausch, [4]Paulina Richter-Pechańska, [5]Ianthe Aem van Belzen, [6]Viktoras Frismantas, [7]Beat Bornhauser, [8]Diana Ordoñez-Rueada, [9]Malte Paulsen, [10]Vladimir Benes, ..., [22]Martina U Muckenthaler, [23]Jan Korbel, [24]Andreas E Kulozik [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.15252/EMMM.202012104
PubMed: 32755029 | | 2020-08-05 |
| 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations | [1]Carole Trzaska, [2]Séverine Amand, [3]Christine Bailly, [4]Catherine Leroy, [5]Virginie Marchand, [6]Evelyne Duvernois-Berthet, [7]Jean-Michel Saliou, [8]Hana Benhabiles, [9]Elisabeth Werkmeister, [10]Thierry Chassat, ..., [15]Pierre-Arthur Moreau, [16]Eric Adriaenssens, [17]Andreas E Kulozik, [18]Eric Westhof, [19]David Tulasne, ... [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-020-15140-Z
PubMed: 32198346 | | 2020-03-20 |
| Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma | [1]Ann-Kathrin Desch, [2]Kristin Hartung, [3]Ante Botzen, [4]Alexander Brobeil, [5]Mathias Rummel, [6]Lars Kurch, [7]Thomas Georgi, [8]Theresa Jox, [9]Stefan Bielack, [10]Stefan Burdach, ..., [21]Udo Kontny, [22]Christof Kramm, [23]Andreas E Kulozik, [24]Joachim Kühr, [25]Karl-Walter Sykora, ... [Full author list] | Leukemia [curation] | DOI: 10.1038/S41375-019-0541-6
PubMed: 31431735 | Hodgkin lymphoma [curation] | 2019-08-20 |
| Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation | [1]Serap Erkek, [2]Pascal Johann, [3]Martina A Finetti, [4]Yiannis Drosos, [5]Hsien-Chao Chou, [6]Marc Zapatka, [7]Dominik Sturm, [8]David T. W. Jones, [9]Andrey Korshunov, [10]Marina Rhyzova, ..., [13]Katja Beck, [14]Olaf Witt, [15]Andreas E Kulozik, [16]Michael Christoph Frühwald, [17]Paul A Northcott, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCELL.2018.11.014
PubMed: 30595504 | | 2018-12-27 |
| PDX models recapitulate the genetic and epigenetic landscape of pediatric T-cell leukemia | [1]Paulina Richter-Pechańska, [2]Joachim B Kunz, [3]Beat Bornhauser, [4]Caroline von Knebel Doeberitz, [5]Tobias Rausch, [6]Büşra Erarslan-Uysal, [7]Yassen Assenov, [8]Viktoras Frismantas, [9]Blerim Marovca, [10]Sebastian M Waszak, ..., [22]Jan Korbel, [23]Jean-Pierre Bourquin, [24]Andreas E Kulozik [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.15252/EMMM.201809443
PubMed: 30389682 | leukemia [curation]; molecular medicine [curation]; T-cell leukemia [curation] | 2018-12-01 |
| Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility | [1]Mitchell Machiela, [2]Thomas Grunewald, [3]Didier Surdez, [4]Stephanie Reynaud, [5]Olivier Mirabeau, [6]Eric Karlins, [7]Rebeca Alba Rubio, [8]Sakina Zaidi, [9]Sandrine Grossetete-Lalami, [10]Stelly Ballet, ..., [38]Smita Bhatia, [39]Les Robison, [40]Andreas E Kulozik, [41]Jennifer Kriebel, [42]Thomas Meitinger, ... [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-018-05537-2
PubMed: 30093639 | general chemistry [curation]; genome-wide association study [curation] | 2018-08-09 |
| Author Correction: The landscape of genomic alterations across childhood cancers | [1]Susanne N. Gröbner, [2]Barbara C Worst, [3]Joachim Weischenfeldt, [4]Ivo Buchhalter, [5]Kortine Kleinheinz, [6]Vasilisa A Rudneva, [7]Pascal Johann, [8]Gnana Prakash Balasubramanian, [9]Maia Segura-Wang, [10]Sebastian Brabetz, ..., [33]Renate Kirschner-Schwabe, [34]Udo Kontny, [35]Andreas E Kulozik, [36]Dietmar R Lohmann, [37]Simone Hettmer, ... [Full author list] | Nature [curation] | DOI: 10.1038/S41586-018-0167-2
PubMed: 29875405 | | 2018-07-01 |
| Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial | [1]Meinolf Suttorp, [2]Philipp Schulze, [3]Ingmar Glauche, [4]Gudrun Göhring, [5]Nils von Neuhoff, [6]Markus Metzler, [7]Petr Sedláček, [8]Eveline S J M de Bont, [9]Adriana Balduzzi, [10]Birgitte Lausen, ..., [21]Karl Walter Sykora, [22]Arndt Borkhardt, [23]Andreas E Kulozik, [24]Martin Schrappe, [25]Christina Nowasz, ... [Full author list] | Leukemia [curation] | DOI: 10.1038/S41375-018-0179-9
PubMed: 29925908 | leukemia [curation]; imatinib [curation]; chronic myeloid leukemia [curation]; phase III clinical trial [curation] | 2018-06-20 |
| DNA methylation-based classification of central nervous system tumours. | [1]David Capper, [2]David T. W. Jones, [3]Martin Sill, [4]Volker Hovestadt, [5]Daniel Schrimpf, [6]Dominik Sturm, [7]Christian Koelsche, [8]Felix Sahm, [9]Lukas Chavez, [10]David E Reuss, ..., [73]Christian Mawrin, [74]Ralf Ketter, [75]Andreas E Kulozik, [76]Ziad Khatib, [77]Frank L. Heppner, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE26000
PubMed: 29539639 | DNA methylation [curation] | 2018-03-14 |
| The landscape of genomic alterations across childhood cancers. | [1]Susanne N. Gröbner, [2]Barbara C Worst, [3]Joachim Weischenfeldt, [4]Ivo Buchhalter, [5]Kortine Kleinheinz, [6]Vasilisa A Rudneva, [7]Pascal Johann, [8]Gnana Prakash Balasubramanian, [9]Maia Segura-Wang, [10]Sebastian Brabetz, ..., [33]Renate Kirschner-Schwabe, [34]Udo Kontny, [35]Andreas E Kulozik, [36]Dietmar R Lohmann, [37]Simone Hettmer, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE25480
PubMed: 29489754 | | 2018-02-28 |
| Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL. | [1]Franco Locatelli, [2]Maria Grazia Valsecchi, [3]Anja Möricke, [4]Martin Zimmermann, [5]Bernd Gruhn, [6]Andrea Biondi, [7]Andreas E Kulozik, [8]Daniela Silvestri, [9]Nicole Bodmer, [10]Maria Caterina Putti, ... [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2017-05-782086
PubMed: 28939722 | | 2017-09-22 |
| Erratum to: Insights into the design and interpretation of iCLIP experiments | [1]Nejc Haberman, [2]Ina Huppertz, [3]Jan Attig, [4]Julian König, [5]Zhen Wang, [6]Christian Hauer, [7]Matthias Hentze, [8]Andreas E Kulozik, [9]Hervé Le Hir, [10]Tomaž Curk, [11]Christopher R Sibley, [12]Kathi Zarnack, [13]Jernej Ule [Full author list] | Genome Biology [curation] | DOI: 10.1186/S13059-017-1294-Z
PubMed: 28810898 | Insights into the design and interpretation of iCLIP experiments [curation] | 2017-08-15 |
| Bone marrow failure unresponsive to bone marrow transplant is caused by mutations in THPO. | [1]Aaron Seo, [2]Miri Ben-Harosh, [3]Mehtap Sirin, [4]Jerry Stein, [5]Orly Dgany, [6]Joseph Kaplelushnik, [7]Manfred Hoenig, [8]Ulrich Pannicke, [9]Myriam Lorenz, [10]Klaus Schwarz, ..., [17]Mary-Claire King, [18]Holger Cario, [19]Andreas E Kulozik, [20]Klaus-Michael Debatin, [21]Ansgar Schulz, ... [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2017-02-768036
PubMed: 28559357 | | 2017-05-30 |
| Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases | [1]Christian Koelsche, [2]Daniel Schrimpf, [3]Lars Tharun, [4]Eva Roth, [5]Dominik Sturm, [6]David T. W. Jones, [7]Eva Kristin Renker, [8]Martin Sill, [9]Annika Baude, [10]Felix Sahm, ..., [12]Melanie Bewerunge-Hudler, [13]Wolfgang Hartmann, [14]Andreas E Kulozik, [15]Iver Petersen, [16]Uta Flucke, ... [Full author list] | Clinical Sarcoma Research [curation] | DOI: 10.1186/S13569-017-0075-5
PubMed: 28484590 | | 2017-05-04 |
| Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology. | [1]Tim Ripperger, [2]Stefan Bielack, [3]Arndt Borkhardt, [4]Ines B Brecht, [5]Birgit Burkhardt, [6]Gabriele Calaminus, [7]Klaus-Michael Debatin, [8]Hedwig E Deubzer, [9]Uta Dirksen, [10]Cornelia Eckert, ..., [34]Christof M Kramm, [35]Michaela Kuhlen, [36]Andreas E Kulozik, [37]Britta Lamottke, [38]Ivo Leuschner, ... [Full author list] | American Journal of Medical Genetics [curation] | DOI: 10.1002/AJMG.A.38142
PubMed: 28168833 | childhood cancer [curation] | 2017-02-07 |
| Insights into the design and interpretation of iCLIP experiments | [1]Nejc Haberman, [2]Ina Huppertz, [3]Jan Attig, [4]Julian König, [5]Zhen Wang, [6]Christian Hauer, [7]Matthias Hentze, [8]Andreas E Kulozik, [9]Hervé Le Hir, [10]Tomaž Curk, [11]Christopher R Sibley, [12]Kathi Zarnack, [13]Jernej Ule [Full author list] | Genome Biology [curation] | DOI: 10.1186/S13059-016-1130-X
PubMed: 28093074 | | 2017-01-16 |
| Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma | [1]Theophilos Tzaridis, [2]Till Milde, [3]Kristian W Pajtler, [4]Sebastian Bender, [5]David T. W. Jones, [6]Simone Müller, [7]Andrea Wittmann, [8]Magdalena Schlotter, [9]Andreas E Kulozik, [10]Peter Lichter, [11]V Peter Collins, [12]Olaf Witt, [13]Marcel Kool, [14]Andrey Korshunov, [15]Stefan M. Pfister, [16]Hendrik Witt [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.11452
PubMed: 27556362 | | 2016-08-20 |
| Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins | [1]Christian Hauer, [2]Jana Sieber, [3]Thomas Schwarzl, [4]Ina Hollerer, [5]Tomaž Curk, [6]Anne-Marie Alleaume, [7]Matthias Hentze, [8]Andreas E Kulozik [Full author list] | Cell Reports [curation] | DOI: 10.1016/J.CELREP.2016.06.096
PubMed: 27475226 | bias [curation] | 2016-07-28 |
| Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study | [1]Barbara C Worst, [2]Cornelis M van Tilburg, [3]Gnana Prakash Balasubramanian, [4]Petra Fiesel, [5]Ruth Witt, [6]Angelika Freitag, [7]Miream Boudalil, [8]Christopher Previti, [9]Stephan Wolf, [10]Sabine Schmidt, ..., [20]Till Milde, [21]Elke Pfaff, [22]Andreas E Kulozik, [23]Arend von Stackelberg, [24]Roland Meisel, ... [Full author list] | European Journal of Cancer [curation] | DOI: 10.1016/J.EJCA.2016.06.009
PubMed: 27479119 | | 2016-07-28 |
| CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia | [1]Chiara Palmi, [2]Angela M Savino, [3]Daniela Silvestri, [4]Ilaria Bronzini, [5]Gunnar Cario, [6]Maddalena Paganin, [7]Barbara Buldini, [8]Marta Galbiati, [9]Martina U Muckenthaler, [10]Cristina Bugarin, ..., [22]Anna Maria Testi, [23]Ottavio Ziino, [24]Andreas E Kulozik, [25]Martin Zimmermann, [26]Martin Schrappe, ... [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.10610
PubMed: 27449287 | | 2016-07-15 |
| The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion | [1]Ina Hollerer, [2]Tomaž Curk, [3]Bettina Haase, [4]Vladimir Benes, [5]Christian Hauer, [6]Gabriele Neu-Yilik, [7]Madhuri Bhuvanagiri, [8]Matthias Hentze, [9]Andreas E Kulozik [Full author list] | RNA [curation] | DOI: 10.1261/RNA.055657.115
PubMed: 27407180 | | 2016-07-12 |
| MB-57INTERACTION OF HDAC2 AND MYC IN GROUP 3 MEDULLOBLASTOMA - A NOVEL THERAPEUTIC TARGET | [1]Jonas Ecker, [2]Ina Oehme, [3]Florian Selt, [4]Marcel Kool, [5]Martina Schnölzer, [6]Uwe Warnken, [7]Sebastian Brabetz, [8]Robert J Wechsler-Reya, [9]Andreas E Kulozik, [10]Stefan M. Pfister, [11]Olaf Witt, [12]Till Milde [Full author list] | Neuro-Oncology [curation] | DOI: 10.1093/NEUONC/NOW076.54
| medulloblastoma [curation] | 2016-05-30 |
| Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. | [1]Pascal Johann, [2]Serap Erkek, [3]Marc Zapatka, [4]Kornelius Kerl, [5]Ivo Buchhalter, [6]Volker Hovestadt, [7]David T. W. Jones, [8]Dominik Sturm, [9]Carl Hermann, [10]Maia Segura-Wang, ..., [31]Till Milde, [32]Olaf Witt, [33]Andreas E Kulozik, [34]Martin Ebinger, [35]Tarek Shalaby, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCELL.2016.02.001
PubMed: 26923874 | | 2016-02-18 |
| Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000. | [1]Anja Möricke, [2]Martin Zimmermann, [3]Maria Grazia Valsecchi, [4]Martin Stanulla, [5]Andrea Biondi, [6]Georg Mann, [7]Franco Locatelli, [8]Giovanni Cazzaniga, [9]Felix K Niggli, [10]Maurizio Aricò, ..., [15]Giuseppe Basso, [16]Richard Ratei, [17]Andreas E Kulozik, [18]Luca Lo Nigro, [19]Bernhard Kremens, ... [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2015-09-670729
PubMed: 26888258 | dexamethasone [curation] | 2016-02-17 |
| HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA. | [1]Lara Ajamian, [2]Karen Abel, [3]Shringar Rao, [4]Kishanda Vyboh, [5]Francisco García-de-Gracia, [6]Ricardo Soto-Rifo, [7]Andreas E Kulozik, [8]Niels H Gehring, [9]Andrew J Mouland [Full author list] | Biomolecules [curation] | DOI: 10.3390/BIOM5042808
PubMed: 26492277 | | 2015-10-20 |
| Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors. | [1]Florian Selt, [2]Alica Deiß, [3]Andrey Korshunov, [4]David Capper, [5]Hendrik Witt, [6]Cornelis M van Tilburg, [7]David T. W. Jones, [8]Ruth Witt, [9]Felix Sahm, [10]David E Reuss, [11]Christian Kölsche, [12]Jonas Ecker, [13]Ina Oehme, [14]Thomas Hielscher, [15]Andreas von Deimling, [16]Andreas E Kulozik, [17]Stefan M. Pfister, [18]Olaf Witt, [19]Till Milde [Full author list] | Brain Pathology [curation] | DOI: 10.1111/BPA.12326
PubMed: 26445087 | | 2015-10-07 |
| Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation | [1]Joachim B Kunz, [2]Tobias Rausch, [3]Obul R. Bandapalli, [4]Juliane Eilers, [5]Paulina Pechanska, [6]Stephanie Schuessele, [7]Yassen Assenov, [8]Adrian M Stütz, [9]Renate Kirschner-Schwabe, [10]Jana Hof, ..., [21]Jan O Korbel, [22]Martina U Muckenthaler, [23]Andreas E Kulozik [Full author list] | Haematologica [curation] | DOI: 10.3324/HAEMATOL.2015.129692
PubMed: 26294725 | leukemia [curation]; lymphoblastic leukemia [curation] | 2015-08-20 |
| Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP | [1]Christian Hauer, [2]Tomaž Curk, [3]Simon Anders, [4]Thomas Schwarzl, [5]Anne-Marie Alleaume, [6]Jana Sieber, [7]Ina Hollerer, [8]Madhuri Bhuvanagiri, [9]Wolfgang Huber, [10]Matthias Hentze, [11]Andreas E Kulozik [Full author list] | Nature Communications [curation] | DOI: 10.1038/NCOMMS8921
PubMed: 26260686 | | 2015-08-11 |
| Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups | [1]Kristian W Pajtler, [2]Hendrik Witt, [3]Martin Sill, [4]David T. W. Jones, [5]Volker Hovestadt, [6]Fabian Kratochwil, [7]Khalida Wani, [8]Ruth G. Tatevossian, [9]Chandanamali Punchihewa, [10]Pascal Johann, ..., [38]David Zagzag, [39]Martin Hasselblatt, [40]Andreas E Kulozik, [41]Olaf Witt, [42]V Peter Collins, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCELL.2015.04.002
PubMed: 25965575 | ependymal tumor [curation] | 2015-05-01 |
| Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma | [1]Jonas Ecker, [2]Ina Oehme, [3]Ralph Mazitschek, [4]Andrey Korshunov, [5]Marcel Kool, [6]Thomas Hielscher, [7]Judit Kiss, [8]Florian Selt, [9]Carina Konrad, [10]Marco Lodrini, [11]Hedwig E Deubzer, [12]Andreas von Deimling, [13]Andreas E Kulozik, [14]Stefan M. Pfister, [15]Olaf Witt, [16]Till Milde [Full author list] | Acta Neuropathologica Communications [curation] | DOI: 10.1186/S40478-015-0201-7
PubMed: 25853389 | medulloblastoma [curation] | 2015-04-03 |
| Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers | [1]Andrey Korshunov, [2]Marina Ryzhova, [3]Volker Hovestadt, [4]Sebastian Bender, [5]Dominik Sturm, [6]David Capper, [7]Jochen Meyer, [8]Daniel Schrimpf, [9]Marcel Kool, [10]Paul A Northcott, ..., [12]Till Milde, [13]Olaf Witt, [14]Andreas E Kulozik, [15]Guido Reifenberger, [16]Nada Jabado, ... [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-015-1405-4
PubMed: 25752754 | glioblastoma [curation] | 2015-03-10 |
| The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis | [1]Clemens Stockklausner, [2]Anne-Christine Klotter, [3]Nicole Dickemann, [4]Isabelle N Kuhlee, [5]Christin M Duffert, [6]Carolin Kerber, [7]Niels H Gehring, [8]Andreas E Kulozik [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2014-07-587170
PubMed: 25538044 | MPL proto-oncogene, thrombopoietin receptor [curation]; thrombopoietin receptor activity [curation] | 2015-02-12 |
| 5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion | [1]Madhuri Bhuvanagiri, [2]Joe Lewis, [3]Kerstin Putzker, [4]Jonas P Becker, [5]Stefan Leicht, [6]Jeroen Krijgsveld, [7]Richa Batra, [8]Brad Turnwald, [9]Bogdan Jovanovic, [10]Christian Hauer, [11]Jana Sieber, [12]Matthias Hentze, [13]Andreas E Kulozik [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.15252/EMMM.201404461
PubMed: 25319547 | | 2014-12-01 |
| Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups | [1]Hendrik Witt, [2]Martin Sill, [3]Khalida Wani, [4]Steve Mack, [5]David Capper, [6]Stephanie Heim, [7]Pascal Johann, [8]Sally R Lambert, [9]Marina Rhyzova, [10]Volker Hovestadt, ..., [14]Till Milde, [15]Paul A Northcott, [16]Andreas E Kulozik, [17]Olaf Witt, [18]Peter Lichter, ... [Full author list] | Cancer Research [curation] | DOI: 10.1158/1538-7445.AM2014-3094
| brain tumor [curation] | 2014-09-30 |
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma | [1]Paul A Northcott, [2]Catherine Lee, [3]Thomas Zichner, [4]Adrian M Stütz, [5]Serap Erkek, [6]Daisuke Kawauchi, [7]David J. H. Shih, [8]Volker Hovestadt, [9]Marc Zapatka, [10]Dominik Sturm, ..., [67]Jörg Felsberg, [68]Guido Reifenberger, [69]Andreas E Kulozik, [70]Andreas von Deimling, [71]Olaf Witt, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE13379
PubMed: 25043047 | medulloblastoma [curation] | 2014-06-22 |
| Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition | [1]Marcel Kool, [2]David T. W. Jones, [3]Natalie Jäger, [4]Paul A Northcott, [5]Trevor J Pugh, [6]Volker Hovestadt, [7]Rosario M. Piro, [8]L Adriana Esparza, [9]Shirley L Markant, [10]Marc Remke, ..., [44]Christel Herold-Mende, [45]Silvia Hofer, [46]Andreas E Kulozik, [47]Andreas von Deimling, [48]Wolfram Scheurlen, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCR.2014.02.004
PubMed: 24651015 | cell biology [curation]; medulloblastoma [curation] | 2014-03-17 |
| High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol | [1]Gunnar Cario, [2]Peter Rhein, [3]Rita Mitlöhner, [4]Martin Zimmermann, [5]Obul R Bandapalli, [6]Renja Romey, [7]Anja Moericke, [8]Wolf-Dieter Ludwig, [9]Richard Ratei, [10]Martina U Muckenthaler, [11]Andreas E Kulozik, [12]Martin Schrappe, [13]Martin Stanulla, [14]Leonid Karawajew [Full author list] | Haematologica [curation] | DOI: 10.3324/HAEMATOL.2013.090225
PubMed: 23911702 | lymphoblastic leukemia [curation]; T-cell acute lymphoblastic leukemia [curation] | 2014-01-01 |
| mRNA 3'end processing: A tale of the tail reaches the clinic | [1]Ina Hollerer, [2]Kerstin Grund, [3]Matthias Hentze, [4]Andreas E Kulozik [Full author list] | EMBO Molecular Medicine [curation] | DOI: 10.1002/EMMM.201303300
PubMed: 24408965 | | 2014-01-01 |
| Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay | [1]Kusum K Singh, [2]Laurens Wachsmuth, [3]Andreas E Kulozik, [4]Niels H Gehring [Full author list] | RNA Biology [curation] | DOI: 10.4161/RNA.25827
PubMed: 23917022 | cell biology [curation]; Mago homolog B, exon junction complex subunit [curation]; Mago homolog, exon junction complex subunit [curation] | 2013-08-01 |
| Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma | [1]David T. W. Jones, [2]Barbara Hutter, [3]Natalie Jäger, [4]Andrey Korshunov, [5]Marcel Kool, [6]Hans-Jörg Warnatz, [7]Thomas Zichner, [8]Sally R Lambert, [9]Marina Ryzhova, [10]Dong-Anh Khuong-Quang, ..., [49]Christel Herold-Mende, [50]Till Milde, [51]Andreas E Kulozik, [52]Martin Ebinger, [53]Martin U Schuhmann, ... [Full author list] | Nature Genetics [curation] | DOI: 10.1038/NG.2682
PubMed: 23817572 | | 2013-06-30 |
| Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. | [1]Maila Giannandrea, [2]Fabrizia C Guarnieri, [3]Niels H Gehring, [4]Elena Monzani, [5]Fabio Benfenati, [6]Andreas E Kulozik, [7]Flavia Valtorta [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0067724
PubMed: 23818987 | | 2013-06-20 |
| Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency | [1]Johann Greil, [2]Tobias Rausch, [3]Thomas Giese, [4]Obul R. Bandapalli, [5]Volker Daniel, [6]Isabelle Bekeredjian-Ding, [7]Adrian M Stütz, [8]Christoph Drees, [9]Susanne Roth, [10]Jürgen Ruland, [11]Jan O Korbel, [12]Andreas E Kulozik [Full author list] | The Journal of Allergy and Clinical Immunology [curation] | DOI: 10.1016/J.JACI.2013.02.012
PubMed: 23561803 | severe combined immunodeficiency [curation] | 2013-04-03 |
| Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT): establishment of workflow and initial clinical data | [1]Stephanie E. Combs, [2]Kerstin A Kessel, [3]Klaus Herfarth, [4]Alexandra Jensen, [5]Susanne Oertel, [6]Claudia Blattmann, [7]Swantje Ecker, [8]Angelika Hoess, [9]Eike Martin, [10]Olaf Witt, [11]Oliver Jäkel, [12]Andreas E Kulozik, [13]Jürgen Debus [Full author list] | Radiation Oncology [curation] | DOI: 10.1186/1748-717X-7-170
PubMed: 23072718 | heavy ion radiotherapy [curation]; workflow [curation] | 2012-10-17 |
| HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment | [1]Till Milde, [2]Marco Lodrini, [3]Larissa Savelyeva, [4]Andrey Korshunov, [5]Marcel Kool, [6]Lena M Brueckner, [7]André Saraiva Leão Antunes, [8]Ina Oehme, [9]Arnulf Pekrun, [10]Stefan M. Pfister, [11]Andreas E Kulozik, [12]Olaf Witt, [13]Hedwig E Deubzer [Full author list] | Journal of Neuro-Oncology [curation] | DOI: 10.1007/S11060-012-0978-1
PubMed: 23054560 | medulloblastoma [curation]; cell line [curation] | 2012-10-06 |
| Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. | [1]Dominik Sturm, [2]Hendrik Witt, [3]Volker Hovestadt, [4]Dong-Anh Khuong-Quang, [5]David T. W. Jones, [6]Carolin Konermann, [7]Elke Pfaff, [8]Martje Tönjes, [9]Martin Sill, [10]Sebastian Bender, ..., [30]Gregor von Komorowski, [31]Matthias Dürken, [32]Andreas E Kulozik, [33]Jenny Madden, [34]Andrew Donson, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCR.2012.08.024
PubMed: 23079654 | | 2012-10-01 |
| Dissecting the genomic complexity underlying medulloblastoma | [1]David T. W. Jones, [2]Natalie Jäger, [3]Marcel Kool, [4]Thomas Zichner, [5]Barbara Hutter, [6]Marc Sultan, [7]Yoon-Jae Cho, [8]Trevor J Pugh, [9]Volker Hovestadt, [10]Adrian M Stütz, ..., [56]Christel Herold-Mende, [57]Till Milde, [58]Andreas E Kulozik, [59]Andreas von Deimling, [60]Olaf Witt, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE11284
PubMed: 22832583 | medulloblastoma [curation] | 2012-08-02 |
| BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis. | [1]Felix Sahm, [2]David Capper, [3]Matthias Preusser, [4]Jochen Meyer, [5]Albrecht Stenzinger, [6]Felix Lasitschka, [7]Anna Sophie Berghoff, [8]Antje Habel, [9]Marion Schneider, [10]Andreas E Kulozik, [11]Ioannis Anagnostopoulos, [12]Leonhard Müllauer, [13]Gunhild Mechtersheimer, [14]Andreas von Deimling [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2012-06-429597
PubMed: 22859608 | | 2012-08-02 |
| Nestin expression identifies ependymoma patients with poor outcome | [1]Till Milde, [2]Thomas Hielscher, [3]Hendrik Witt, [4]Marcel Kool, [5]Stephen C Mack, [6]Hedwig E Deubzer, [7]Ina Oehme, [8]Marco Lodrini, [9]Axel Benner, [10]Michael D. Taylor, [11]Andreas von Deimling, [12]Andreas E Kulozik, [13]Stefan M. Pfister, [14]Olaf Witt, [15]Andrey Korshunov [Full author list] | Brain Pathology [curation] | DOI: 10.1111/J.1750-3639.2012.00600.X
PubMed: 22568867 | ependymoma [curation]; pediatric ependymoma [curation] | 2012-05-30 |
| Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | [1]Jeremy Schwartzentruber, [2]Andrey Korshunov, [3]Xiao-Yang Liu, [4]David T. W. Jones, [5]Elke Pfaff, [6]Karine Jacob, [7]Dominik Sturm, [8]Adam Fontebasso, [9]Dong-Anh Khuong-Quang, [10]Martje Tönjes, ..., [40]Zhifeng Dong, [41]Peter M Siegel, [42]Andreas E Kulozik, [43]Marc Zapatka, [44]Abhijit Guha Roy, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE11026
| glioblastoma [curation]; Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma [curation] | 2012-03-28 |
| Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | [1]Jeremy Schwartzentruber, [2]Andrey Korshunov, [3]Xiao-Yang Liu, [4]David T. W. Jones, [5]Elke Pfaff, [6]Karine Jacob, [7]Dominik Sturm, [8]Adam Fontebasso, [9]Dong-Anh Khuong-Quang, [10]Martje Tönjes, ..., [40]Zhifeng Dong, [41]Peter M Siegel, [42]Andreas E Kulozik, [43]Marc Zapatka, [44]Abhijit Guha Roy, ... [Full author list] | Nature [curation] | DOI: 10.1038/NATURE10833
PubMed: 22286061 | glioblastoma [curation] | 2012-01-29 |
| Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations | [1]Tobias Rausch, [2]David T. W. Jones, [3]Marc Zapatka, [4]Adrian M Stütz, [5]Thomas Zichner, [6]Joachim Weischenfeldt, [7]Natalie Jäger, [8]Marc Remke, [9]David J. H. Shih, [10]Paul A Northcott, ..., [26]Jonathon Blake, [27]Vladimir Benes, [28]Andreas E Kulozik, [29]Olaf Witt, [30]Dianna C Martin, ... [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2011.12.013
PubMed: 22265402 | medulloblastoma [curation] | 2012-01-01 |
| Biological and clinical heterogeneity of MYCN-amplified medulloblastoma | [1]Andrey Korshunov, [2]Marc Remke, [3]Marcel Kool, [4]Thomas Hielscher, [5]Paul A Northcott, [6]Dan Williamson, [7]Elke Pfaff, [8]Hendrik Witt, [9]David T. W. Jones, [10]Marina Ryzhova, ..., [15]Andreas von Deimling, [16]Wolfram Scheurlen, [17]Andreas E Kulozik, [18]Steven Clifford, [19]V Peter Collins, ... [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-011-0918-8
PubMed: 22160402 | medulloblastoma [curation] | 2011-12-09 |
| MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. | [1]Alfa H C Bai, [2]Till Milde, [3]Marc Remke, [4]Claudio G Rolli, [5]Thomas Hielscher, [6]Yoon-Jae Cho, [7]Marcel Kool, [8]Paul A Northcott, [9]Manfred Jugold, [10]Alexandr V Bazhin, [11]Stefan Eichmüller, [12]Andreas E Kulozik, [13]Armin Pscherer, [14]Axel Benner, ... [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-011-0924-X
PubMed: 22134538 | microRNA [curation]; medulloblastoma [curation] | 2011-12-02 |
| Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines | [1]Susanne Oertel, [2]Markus Thiemann, [3]Karsten Richter, [4]Klaus J Weber, [5]Peter E Huber, [6]Ramon Lopez Perez, [7]Stephan Brons, [8]Marc Bischof, [9]Andreas E Kulozik, [10]Volker Ehemann, [11]Jürgen Debus, [12]Claudia Blattmann [Full author list] | Radiation Oncology [curation] | DOI: 10.1186/1748-717X-6-119
PubMed: 21933400 | lithium-ion battery [curation] | 2011-09-20 |
| FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma | [1]Marc Remke, [2]Thomas Hielscher, [3]Andrey Korshunov, [4]Paul A Northcott, [5]Sebastian Bender, [6]Marcel Kool, [7]Frank Westermann, [8]Axel Benner, [9]Huriye Seker-Cin, [10]Marina Ryzhova, ..., [19]Stefan Rutkowski, [20]Wolfram Scheurlen, [21]Andreas E Kulozik, [22]Michael D. Taylor, [23]Peter Lichter, ... [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2011.36.2798
PubMed: 21911727 | medulloblastoma [curation] | 2011-09-12 |
| A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat | [1]Till Milde, [2]Susanne Kleber, [3]Andrey Korshunov, [4]Hendrik Witt, [5]Thomas Hielscher, [6]Philipp Koch, [7]Hans-Georg Kopp, [8]Manfred Jugold, [9]Hedwig E Deubzer, [10]Ina Oehme, [11]Marco Lodrini, [12]Hermann-Josef Gröne, [13]Axel Benner, [14]Oliver Brüstle, [15]Richard Gilbertson, [16]Andreas von Deimling, [17]Andreas E Kulozik, [18]Stefan M. Pfister, [19]Ana Martín-Villalba, [20]Olaf Witt [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-011-0866-3
PubMed: 21863243 | ependymoma [curation]; pediatric ependymoma [curation] | 2011-08-24 |
| Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma | [1]Hendrik Witt, [2]Stephen C Mack, [3]Marina Ryzhova, [4]Sebastian Bender, [5]Martin Sill, [6]Ruth Isserlin, [7]Axel Benner, [8]Thomas Hielscher, [9]Till Milde, [10]Marc Remke, ..., [24]Yoon-Jae Cho, [25]Andreas von Deimling, [26]Andreas E Kulozik, [27]Olaf Witt, [28]Gary D. Bader, ... [Full author list] | Cancer Cell [curation] | DOI: 10.1016/J.CCR.2011.07.007
PubMed: 21840481 | ependymoma [curation]; pediatric ependymoma [curation] | 2011-08-01 |
| Adult medulloblastoma comprises three major molecular variants. | [1]Marc Remke, [2]Thomas Hielscher, [3]Paul A Northcott, [4]Hendrik Witt, [5]Marina Ryzhova, [6]Andrea Wittmann, [7]Axel Benner, [8]Andreas von Deimling, [9]Wolfram Scheurlen, [10]Arie Perry, [11]Sidney E. Croul, [12]Andreas E Kulozik, [13]Peter Lichter, [14]Michael D. Taylor, [15]Stefan M. Pfister, [16]Andrey Korshunov [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2011.34.9373
PubMed: 21632505 | medulloblastoma [curation]; adult medulloblastoma [curation] | 2011-05-31 |
| Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias | [1]Chen Shochat, [2]Noa Tal, [3]Obul R. Bandapalli, [4]Chiara Palmi, [5]Ithamar Ganmore, [6]Geertruy Te Kronnie, [7]Gunnar Cario, [8]Giovanni Cazzaniga, [9]Andreas E Kulozik, [10]Martin Stanulla, [11]Martin Schrappe, [12]Andrea Biondi, [13]Giuseppe Basso, [14]Dani Bercovich, [15]Martina U Muckenthaler, [16]Shai Izraeli [Full author list] | Journal of Experimental Medicine [curation] | DOI: 10.1084/JEM.20110580
PubMed: 21536738 | leukemia [curation]; interleukins [curation] | 2011-05-02 |
| Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon | [1]Gabriele Neu-Yilik, [2]Beate Amthor, [3]Niels H Gehring, [4]Sharif Bahri, [5]Helena Paidassi, [6]Matthias Hentze, [7]Andreas E Kulozik [Full author list] | RNA [curation] | DOI: 10.1261/RNA.2401811
PubMed: 21389146 | | 2011-05-01 |
| Reply to J.C. Lindsey et al | [1]Elke Pfaff, [2]Marc Remke, [3]Dominik Sturm, [4]Axel Benner, [5]Hendrik Witt, [6]Till Milde, [7]André O von Bueren, [8]Norbert Jorch, [9]Norbert Graf, [10]Andreas E Kulozik, [11]Olaf Witt, [12]Wolfram Scheurlen, [13]Andreas von Deimling, [14]Stefan Rutkowski, [15]Michael D. Taylor, [16]Uri Tabori, [17]Peter Lichter, [18]Andrey Korshunov, [19]Stefan M. Pfister [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2010.34.1545
| | 2011-04-20 |
| Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma | [1]Huriye Seker-Cin, [2]Claus Meyer, [3]Ricarda Herr, [4]Wibke G Janzarik, [5]Sally R Lambert, [6]David T. W. Jones, [7]Karine Jacob, [8]Axel Benner, [9]Hendrik Witt, [10]Marc Remke, ..., [15]Andreas von Deimling, [16]Arnulf Pekrun, [17]Andreas E Kulozik, [18]Astrid K Gnekow, [19]Wolfram Scheurlen, ... [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-011-0817-Z
PubMed: 21424530 | | 2011-03-20 |
| p38 MAPK controls prothrombin expression by regulated RNA 3' end processing | [1]Sven Danckwardt, [2]Anne-Susan Gantzert, [3]Stephan Macher-Goeppinger, [4]Hans Christian Probst, [5]Marc Gentzel, [6]Matthias Wilm, [7]Hermann-Josef Gröne, [8]Peter Schirmacher, [9]Matthias Hentze, [10]Andreas E Kulozik [Full author list] | Molecular Cell [curation] | DOI: 10.1016/J.MOLCEL.2010.12.032
PubMed: 21292162 | | 2011-02-01 |
| TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. | [1]Elke Pfaff, [2]Marc Remke, [3]Dominik Sturm, [4]Axel Benner, [5]Hendrik Witt, [6]Till Milde, [7]André O von Bueren, [8]Andrea Wittmann, [9]Anna Schöttler, [10]Norbert Jorch, [11]Norbert Graf, [12]Andreas E Kulozik, [13]Olaf Witt, [14]Wolfram Scheurlen, ... [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2010.31.1670
PubMed: 21060032 | medulloblastoma [curation] | 2010-11-08 |
| Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma | [1]Christopher Traenka, [2]Marc Remke, [3]Andrey Korshunov, [4]Sebastian Bender, [5]Thomas Hielscher, [6]Paul A Northcott, [7]Hendrik Witt, [8]Marina Ryzhova, [9]Jörg Felsberg, [10]Axel Benner, [11]Stephanie Riester, [12]Wolfram Scheurlen, [13]Thomas G P Grunewald, [14]Andreas von Deimling, [15]Andreas E Kulozik, [16]Guido Reifenberger, [17]Michael D. Taylor, [18]Peter Lichter, [19]Elke Butt, [20]Stefan M. Pfister [Full author list] | Cancer Research [curation] | DOI: 10.1158/0008-5472.CAN-10-0592
PubMed: 20924110 | medulloblastoma [curation]; SH3 domain [curation] | 2010-10-05 |
| Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept | [1]Stefan Rieken, [2]Timo Gaiser, [3]Angela Mohr, [4]Thomas Welzel, [5]Olaf Witt, [6]Andreas E Kulozik, [7]Wolfgang Wick, [8]Jürgen Debus, [9]Stephanie E. Combs [Full author list] | BMC Cancer [curation] | DOI: 10.1186/1471-2407-10-450
PubMed: 20731859 | medulloblastoma [curation]; desmoplastic medulloblastoma [curation] | 2010-08-23 |
| Molecular staging of intracranial ependymoma in children and adults | [1]Andrey Korshunov, [2]Hendrik Witt, [3]Thomas Hielscher, [4]Axel Benner, [5]Marc Remke, [6]Marina Ryzhova, [7]Till Milde, [8]Sebastian Bender, [9]Andrea Wittmann, [10]Anna Schöttler, [11]Andreas E Kulozik, [12]Olaf Witt, [13]Andreas von Deimling, [14]Peter Lichter, [15]Stefan M. Pfister [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2009.27.3359
PubMed: 20516456 | ependymoma [curation]; pediatric ependymoma [curation] | 2010-06-01 |
| Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. | [1]Andrey Korshunov, [2]Marc Remke, [3]Wiebke Werft, [4]Axel Benner, [5]Marina Ryzhova, [6]Hendrik Witt, [7]Dominik Sturm, [8]Andrea Wittmann, [9]Anna Schöttler, [10]Jörg Felsberg, [11]Guido Reifenberger, [12]Stefan Rutkowski, [13]Wolfram Scheurlen, [14]Andreas E Kulozik, [15]Andreas von Deimling, [16]Peter Lichter, [17]Stefan M. Pfister [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2009.25.7121
PubMed: 20479417 | algorithm [curation] | 2010-05-17 |
| Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes | [1]Andrey Korshunov, [2]Marc Remke, [3]Marco Gessi, [4]Marina Ryzhova, [5]Thomas Hielscher, [6]Hendrik Witt, [7]Vivienne Tobias, [8]Anna Maria Buccoliero, [9]Iacopo Sardi, [10]Marina Paola Gardiman, [11]Jose Bonnin, [12]Bernd Walter Scheithauer, [13]Andreas E Kulozik, [14]Olaf Witt, [15]Sverre J Mörk, ... [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-010-0688-8
PubMed: 20407781 | diagnosis [curation] | 2010-04-21 |
| Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma | [1]Claudia Blattmann, [2]Susanne Oertel, [3]Daniela Schulz-Ertner, [4]Stefan Rieken, [5]Sabine Haufe, [6]Volker Ewerbeck, [7]Andreas Unterberg, [8]Irini Karapanagiotou-Schenkel, [9]Stephanie E. Combs, [10]Anna Nikoghosyan, [11]Marc Bischof, [12]Oliver Jäkel, [13]Peter Huber, [14]Andreas E Kulozik, [15]Jürgen Debus [Full author list] | BMC Cancer [curation] | DOI: 10.1186/1471-2407-10-96
PubMed: 20226028 | Adaptive radiation therapy [curation]; heavy ion radiotherapy [curation] | 2010-03-12 |
| Hemoglobinopathies are on the increase | [1]Andreas E Kulozik [Full author list] | Deutsches Ärzteblatt international [curation] | DOI: 10.3238/ARZTEBL.2010.0063
PubMed: 20186310 | | 2010-02-01 |
| Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome. | [1]Juliane Rieber, [2]Marc Remke, [3]Christian Hartmann, [4]Andrey Korshunov, [5]Birgit Burkhardt, [6]Dominik Sturm, [7]Gunhild Mechtersheimer, [8]Andrea Wittmann, [9]Johann Greil, [10]Claudia Blattmann, [11]Olaf Witt, [12]Wolfgang Behnisch, [13]Marc-Eric Halatsch, [14]Berk Orakcioglu, [15]Andreas von Deimling, [16]Peter Lichter, [17]Andreas E Kulozik, [18]Stefan M. Pfister [Full author list] | Genes, Chromosomes and Cancer [curation] | DOI: 10.1002/GCC.20665
PubMed: 19378321 | | 2009-07-01 |
| The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay | [1]Niels H Gehring, [2]Styliani Lamprinaki, [3]Matthias Hentze, [4]Andreas E Kulozik [Full author list] | PLOS Biology [curation] | DOI: 10.1371/JOURNAL.PBIO.1000120
PubMed: 19478851 | spliceosome [curation] | 2009-05-26 |
| Disassembly of exon junction complexes by PYM | [1]Niels H Gehring, [2]Styliani Lamprinaki, [3]Andreas E Kulozik, [4]Matthias Hentze [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2009.02.042
PubMed: 19410547 | PYM homolog 1, exon junction complex associated factor [curation]; RNA binding motif protein 8A [curation]; Mago homolog, exon junction complex subunit [curation] | 2009-05-01 |
| Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci | [1]Stefan M. Pfister, [2]Marc Remke, [3]Axel Benner, [4]Frank Mendrzyk, [5]Grischa Toedt, [6]Jörg Felsberg, [7]Andrea Wittmann, [8]Frauke Devens, [9]Nicolas Gerber, [10]Stefan Joos, [11]Andreas E Kulozik, [12]Guido Reifenberger, [13]Stefan Rutkowski, [14]Otmar Wiestler, [15]Bernhard Radlwimmer, [16]Wolfram Scheurlen, [17]Peter Lichter, [18]Andrey Korshunov [Full author list] | Journal of Clinical Oncology [curation] | DOI: 10.1200/JCO.2008.17.9432
PubMed: 19255330 | medulloblastoma [curation] | 2009-04-01 |
| Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes. | [1]Stefan M. Pfister, [2]Marc Remke, [3]Mirco Castoldi, [4]Alfa H C Bai, [5]Martina U Muckenthaler, [6]Andreas E Kulozik, [7]Andreas von Deimling, [8]Armin Pscherer, [9]Peter Lichter, [10]Andrey Korshunov [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-008-0467-Y
PubMed: 19057917 | microRNA [curation] | 2008-12-05 |
| BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas | [1]Stefan M. Pfister, [2]Wibke G Janzarik, [3]Marc Remke, [4]Aurelie Ernst, [5]Wiebke Werft, [6]Natalia Becker, [7]Grischa Toedt, [8]Andrea Wittmann, [9]Christian Kratz, [10]Heike Olbrich, ..., [13]Stefan Joos, [14]Bernhard Radlwimmer, [15]Andreas E Kulozik, [16]Torsten Pietsch, [17]Christel Herold-Mende, ... [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI33656
PubMed: 18398503 | gene duplication [curation] | 2008-05-01 |
| Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation | [1]Lara Ajamian, [2]Levon Abrahamyan, [3]Miroslav Milev, [4]Pavel Ivanov, [5]Andreas E Kulozik, [6]Niels H Gehring, [7]Andrew J Mouland [Full author list] | RNA [curation] | DOI: 10.1261/RNA.829208
PubMed: 18369187 | | 2008-03-27 |
| Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways | [1]Pavel Ivanov, [2]Niels H Gehring, [3]Joachim B Kunz, [4]Matthias Hentze, [5]Andreas E Kulozik [Full author list] | The EMBO Journal [curation] | DOI: 10.1038/EMBOJ.2008.17
PubMed: 18256688 | | 2008-03-05 |
| 3' end mRNA processing: molecular mechanisms and implications for health and disease | [1]Sven Danckwardt, [2]Matthias Hentze, [3]Andreas E Kulozik [Full author list] | The EMBO Journal [curation] | DOI: 10.1038/SJ.EMBOJ.7601932
PubMed: 18256699 | | 2008-02-06 |
| Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas. | [1]Stefan M. Pfister, [2]Marc Remke, [3]Grischa Toedt, [4]Wiebke Werft, [5]Axel Benner, [6]Frank Mendrzyk, [7]Andrea Wittmann, [8]Frauke Devens, [9]Katja von Hoff, [10]Stefan Rutkowski, [11]Andreas E Kulozik, [12]Bernhard Radlwimmer, [13]Wolfram Scheurlen, [14]Peter Lichter, [15]Andrey Korshunov [Full author list] | Genes, Chromosomes and Cancer [curation] | DOI: 10.1002/GCC.20471
PubMed: 17592618 | | 2007-09-01 |
| Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals | [1]Sven Danckwardt, [2]Isabelle Kaufmann, [3]Marc Gentzel, [4]Konrad Förstner, [5]Anne-Susan Gantzert, [6]Niels H Gehring, [7]Gabriele Neu-Yilik, [8]Peer Bork, [9]Walter Keller, [10]Matthias Wilm, [11]Matthias Hentze, [12]Andreas E Kulozik [Full author list] | The EMBO Journal [curation] | DOI: 10.1038/SJ.EMBOJ.7601699
PubMed: 17464285 | | 2007-04-26 |
| Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation | [1]Joachim B Kunz, [2]Gabriele Neu-Yilik, [3]Matthias Hentze, [4]Andreas E Kulozik, [5]Niels H Gehring [Full author list] | RNA [curation] | DOI: 10.1261/RNA.12506
PubMed: 16601204 | UPF1 RNA helicase and ATPase [curation]; CASC3 exon junction complex subunit [curation]; UPF3B regulator of nonsense mediated mRNA decay [curation]; RNA binding motif protein 8A [curation]; UPF2 regulator of nonsense mediated mRNA decay [curation]; UPF3A regulator of nonsense mediated mRNA decay [curation]; Eukaryotic translation initiation factor 4A3 [curation]; Mago homolog, exon junction complex subunit [curation] | 2006-06-01 |
| The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD). | [1]Clemens Stockklausner, [2]Stephen Breit, [3]Gabriele Neu-Yilik, [4]Nicole Echner, [5]Matthias Hentze, [6]Andreas E Kulozik, [7]Niels H Gehring [Full author list] | Nucleic Acids Research [curation] | DOI: 10.1093/NAR/GKL277
PubMed: 16679454 | | 2006-05-05 |
| A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA) | [1]Mirco Castoldi, [2]Sabine Schmidt, [3]Vladimir Benes, [4]Mikkel Noerholm, [5]Andreas E Kulozik, [6]Matthias Hentze, [7]Martina U Muckenthaler [Full author list] | RNA [curation] | DOI: 10.1261/RNA.2332406
PubMed: 16540696 | microRNA expression [curation] | 2006-03-15 |
| Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements | [1]Niels H Gehring, [2]Joachim B Kunz, [3]Gabriele Neu-Yilik, [4]Stephen Breit, [5]Marcelo H Viegas, [6]Matthias Hentze, [7]Andreas E Kulozik [Full author list] | Molecular Cell [curation] | DOI: 10.1016/J.MOLCEL.2005.08.012
PubMed: 16209946 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [curation]; RNA binding motif protein 8A [curation]; RNA binding protein with serine rich domain 1 [curation]; Eukaryotic translation initiation factor 4A3 [curation]; Mago homolog, exon junction complex subunit [curation] | 2005-10-07 |
| Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife | [1]Gabriele Neu-Yilik, [2]Niels H Gehring, [3]Matthias Hentze, [4]Andreas E Kulozik [Full author list] | Genome Biology [curation] | DOI: 10.1186/GB-2004-5-4-218
PubMed: 15059251 | vacuum [curation]; genetic variation [curation]; regulation of gene expression [curation] | 2004-03-30 |
| Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells | [1]Thomas Schell, [2]Thomas Köcher, [3]Matthias Wilm, [4]Bertrand Séraphin, [5]Andreas E Kulozik, [6]Matthias Hentze [Full author list] | Biochemical Journal [curation] | DOI: 10.1042/BJ20021920
PubMed: 12723973 | cell biology [curation] | 2003-08-01 |
| Y14 and hUpf3b form an NMD-activating complex | [1]Niels H Gehring, [2]Gabriele Neu-Yilik, [3]Thomas Schell, [4]Matthias Hentze, [5]Andreas E Kulozik [Full author list] | Molecular Cell [curation] | DOI: 10.1016/S1097-2765(03)00142-4
PubMed: 12718880 | UPF3B regulator of nonsense mediated mRNA decay [curation] | 2003-04-01 |
| Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay | [1]Sven Danckwardt, [2]Gabriele Neu-Yilik, [3]Rolf Thermann, [4]Ute Frede, [5]Matthias Hentze, [6]Andreas E Kulozik [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD.V99.5.1811
PubMed: 11861299 | | 2002-03-01 |
| Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway | [1]Thomas Schell, [2]Andreas E Kulozik, [3]Matthias Hentze [Full author list] | Genome Biology [curation] | DOI: 10.1186/GB-2002-3-3-REVIEWS1006
PubMed: 11897029 | protein biosynthesis [curation]; genetic variation [curation]; regulation of gene expression [curation]; quality control [curation] | 2002-02-26 |
| The human intronless melanocortin 4-receptor gene is NMD insensitive | [1]Katja S Brocke, [2]Gabriele Neu-Yilik, [3]Niels H Gehring, [4]Matthias Hentze, [5]Andreas E Kulozik [Full author list] | Human Molecular Genetics [curation] | DOI: 10.1093/HMG/11.3.331
PubMed: 11823452 | | 2002-02-01 |