| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia | [1]Luke W Thomas, [2]Cinzia Esposito, [3]Rachel E Morgan, [4]Stacey Price, [5]Jamie Young, [6]Steven P Williams, [7]Lucas A Maddalena, [8]Ultan McDermott, [9]Margaret Ashcroft [Full author list] | Communications Biology [curation] | DOI: 10.1038/S42003-021-02098-X
PubMed: 34021238 | | 2021-05-21 |
| Hypoxic microenvironment shapes HIV-1 replication and latency | [1]Xiaodong Zhuang, [2]Isabela Pedroza-Pacheco, [3]Isabel Nawroth, [4]Anna E Kliszczak, [5]Andrea Magri, [6]Wayne Paes, [7]Claudia Orbegozo Rubio, [8]Hongbing Yang, [9]Margaret Ashcroft, [10]David Robert Mole, [11]Peter Balfe, [12]Persephone Borrow, [13]Jane A. McKeating [Full author list] | Communications Biology [curation] | DOI: 10.1038/S42003-020-1103-1
PubMed: 32665623 | | 2020-07-14 |
| CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism | [1]Luke W Thomas, [2]Cinzia Esposito, [3]Jenna M Stephen, [4]Ana S H Costa, [5]Christian Frezza, [6]Thomas S Blacker, [7]Gyorgy Szabadkai, [8]Margaret Ashcroft [Full author list] | Cancer & Metabolism [curation] | DOI: 10.1186/S40170-019-0200-4
PubMed: 31346464 | | 2019-07-16 |
| Exploring the molecular interface between hypoxia-inducible factor signalling and mitochondria | [1]Luke W Thomas, [2]Margaret Ashcroft [Full author list] | Cellular and Molecular Life Sciences [curation] | DOI: 10.1007/S00018-019-03039-Y
PubMed: 30767037 | oxygen [curation]; hypoxia [curation]; energy metabolism [curation]; HIF [nucleoplasm] [curation]; hypoxia-inducible factor 1 [curation]; cell hypoxia [curation] | 2019-05-01 |
| CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain | [1]Luke W Thomas, [2]Jenna M Stephen, [3]Cinzia Esposito, [4]Simon Hoer, [5]Robin Antrobus, [6]Afshan Ahmed, [7]Hasan Al-Habib, [8]Margaret Ashcroft [Full author list] | Cancer & Metabolism [curation] | DOI: 10.1186/S40170-019-0194-Y
PubMed: 30886710 | Mitochondrial respiratory chain complex I [curation]; Tumour Metabolism [curation] | 2019-03-06 |
| Mutations in mitochondrial DNA causing tubulointerstitial kidney disease | [1]Thomas M Connor, [2]Simon Hoer, [3]Andrew Mallett, [4]Daniel P Gale, [5]Aurora Gomez-Duran, [6]Viktor Posse, [7]Robin Antrobus, [8]Pablo Moreno, [9]Marco Sciacovelli, [10]Christian Frezza, [11]Jennifer Duff, [12]Neil S Sheerin, [13]John A. Sayer, [14]Margaret Ashcroft, [15]Michael S Wiesener, [16]Gavin Hudson, [17]Claes M. Gustafsson, [18]Patrick F. Chinnery, [19]Patrick H. Maxwell [Full author list] | PLOS Genetics [curation] | DOI: 10.1371/JOURNAL.PGEN.1006620
PubMed: 28267784 | mitochondrial DNA [curation] | 2017-03-07 |