| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns | [1]David M Asher, [2]Ermias D Belay, [3]Eileen H Bigio, [4]Sebastian Brandner, [5]Scott A Brubaker, [6]Byron Caughey, [7]Brychan Clark, [8]Inger K. Damon, [9]Marc Diamond, [10]Michelle Freund, ..., [20]Julie A Schneider, [21]Lawrence B. Schonberger, [22]Christina J. Sigurdson, [23]Nina Silverberg, [24]John Q. Trojanowski, ... [Full author list] | Journal of Neuropathology & Experimental Neurology [curation] | DOI: 10.1093/JNEN/NLAA109
PubMed: 33000167 | | 2020-10-01 |
| A soluble derivative of PrPC activates cell-signaling and regulates cell physiology through LRP1 and the NMDA Receptor | [1]Elisabetta Mantuano, [2]Pardis Azmoon, [3]Michael A Banki, [4]Michael S Lam, [5]Christina J. Sigurdson, [6]Steven L Gonias [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.RA120.013779
PubMed: 32788217 | cell physiology [curation] | 2020-08-11 |
| Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease | [1]Julia A Callender, [2]Alejandro M Sevillano, [3]Katrin Soldau, [4]Timothy D Kurt, [5]Taylor Schumann, [6]Donald P Pizzo, [7]Hermann Altmeppen, [8]Markus Glatzel, [9]Jeffrey D Esko, [10]Christina J. Sigurdson [Full author list] | Neurobiology of Disease [curation] | DOI: 10.1016/J.NBD.2020.104955
PubMed: 32454127 | | 2020-05-23 |
| Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease | [1]Alejandro M Sevillano, [2]Patricia Aguilar-Calvo, [3]Timothy D Kurt, [4]Jessica A Lawrence, [5]Katrin Soldau, [6]Thu H Nam, [7]Taylor Schumann, [8]Donald P Pizzo, [9]Sofie Nyström, [10]Biswa Choudhury, [11]Hermann Altmeppen, [12]Jeffrey D Esko, [13]Markus Glatzel, [14]K Peter R Nilsson, [15]Christina J. Sigurdson [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI131564
PubMed: 31985492 | | 2020-03-01 |
| Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions | [1]Patricia Aguilar-Calvo, [2]Alejandro M Sevillano, [3]Jaidev Bapat, [4]Katrin Soldau, [5]Daniel R Sandoval, [6]Hermann C Altmeppen, [7]Luise Linsenmeier, [8]Donald P Pizzo, [9]Michael Geschwind, [10]Henry Sanchez, [11]Brian S Appleby, [12]Mark L Cohen, [13]Jiri G Safar, [14]Steven D Edland, [15]Markus Glatzel, [16]K Peter R Nilsson, [17]Jeffrey D Esko, [18]Christina J. Sigurdson [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-019-02085-X
PubMed: 31673874 | | 2019-10-31 |
| Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue | [1]Marius Kollmer, [2]William Close, [3]Leonie Funk, [4]Jay Rasmussen, [5]Aref Bsoul, [6]Angelika Schierhorn, [7]Matthias Schmidt, [8]Christina J. Sigurdson, [9]Mathias Jucker, [10]Marcus Fändrich [Full author list] | Nature Communications [curation] | DOI: 10.1038/S41467-019-12683-8
PubMed: 31664019 | brain tissue [curation] | 2019-10-29 |
| Recent advances on the molecular pathogenesis of prion diseases | [1]Markus Glatzel, [2]Christina J. Sigurdson [Full author list] | Brain Pathology [curation] | DOI: 10.1111/BPA.12693
PubMed: 30588674 | | 2019-03-01 |
| Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease | [1]Allison Kraus, [2]Eri Saijo, [3]Michael A Metrick, [4]Kathy L. Newell, [5]Christina J. Sigurdson, [6]Gianluigi Zanusso, [7]Bernardino F. Ghetti, [8]Byron Caughey [Full author list] | Acta Neuropathologica [curation] | DOI: 10.1007/S00401-018-1947-3
PubMed: 30570675 | | 2018-12-20 |
| Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients | [1]Christina D Orrù, [2]Katrin Soldau, [3]Christian Cordano, [4]Jorge Llibre-Guerra, [5]Ari J Green, [6]Henry Sanchez, [7]Bradley R Groveman, [8]Steven D Edland, [9]Jiri G Safar, [10]Jonathan H Lin, [11]Byron Caughey, [12]Michael Geschwind, [13]Christina J. Sigurdson [Full author list] | mBio [curation] | DOI: 10.1128/MBIO.02095-18
PubMed: 30459197 | sporadic Creutzfeldt-Jakob disease [curation] | 2018-11-20 |
| Cellular and Molecular Mechanisms of Prion Disease | [1]Christina J. Sigurdson, [2]Jason C Bartz, [3]Markus Glatzel [Full author list] | Annual Review of Pathology: Mechanisms of Disease [curation] | DOI: 10.1146/ANNUREV-PATHMECHDIS-012418-013109
PubMed: 30355150 | | 2018-10-24 |
| Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids | [1]Kevin J Cao, [2]Kristyna M Elbel, [3]Jessica L Cifelli, [4]Jordi Cirera, [5]Christina J. Sigurdson, [6]Francesco Paesani, [7]Emmanuel A Theodorakis, [8]Jerry Yang [Full author list] | Scientific Reports [curation] | DOI: 10.1038/S41598-018-25131-2
PubMed: 29725045 | | 2018-05-03 |
| Generation of novel neuroinvasive prions following intravenous challenge. | [1]Patricia Aguilar-Calvo, [2]Cyrus Bett, [3]Alejandro M Sevillano, [4]Timothy D Kurt, [5]Jessica Lawrence, [6]Katrin Soldau, [7]Per Hammarström, [8]K Peter R Nilsson, [9]Christina J. Sigurdson [Full author list] | Brain Pathology [curation] | DOI: 10.1111/BPA.12598
PubMed: 29505163 | prion protein family [curation] | 2018-03-05 |
| Electron microscopic and confocal laser microscopy analysis of amyloid plaques in chronic wasting disease transmitted to transgenic mice | [1]Beata Sikorska, [2]Agata Gajos, [3]Andrzej Bogucki, [4]Emil Zielonka, [5]Christina J. Sigurdson, [6]Paweł P. Liberski [Full author list] | Prion [curation] | DOI: 10.1080/19336896.2017.1384109
PubMed: 29105545 | chronic wasting disease [curation] | 2017-11-06 |
| Asparagine and glutamine ladders promote cross-species prion conversion | [1]Timothy D Kurt, [2]Patricia Aguilar-Calvo, [3]Lin Jiang, [4]José A Rodriguez, [5]Nazilla Alderson, [6]David S Eisenberg, [7]Christina J. Sigurdson [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M117.794107
PubMed: 28931606 | prion protein family [curation] | 2017-09-20 |
| Enhanced neuroinvasion by smaller, soluble prions | [1]Cyrus Bett, [2]Jessica Lawrence, [3]Timothy D Kurt, [4]Christina Orru, [5]Patricia Aguilar-Calvo, [6]Anthony E Kincaid, [7]Witold K Surewicz, [8]Byron Caughey, [9]Chengbiao Wu, [10]Christina J. Sigurdson [Full author list] | Acta Neuropathologica Communications [curation] | DOI: 10.1186/S40478-017-0430-Z
PubMed: 28431576 | prion protein family [curation] | 2017-04-21 |
| Post-translational modifications in PrP expand the conformational diversity of prions in vivo | [1]Patricia Aguilar-Calvo, [2]Xiangzhu Xiao, [3]Cyrus Bett, [4]Hasier Eraña, [5]Katrin Soldau, [6]Joaquín Castilla, [7]K Peter R Nilsson, [8]Witold K Surewicz, [9]Christina J. Sigurdson [Full author list] | Scientific Reports [curation] | DOI: 10.1038/SREP43295
PubMed: 28272426 | prion protein family [curation] | 2017-03-08 |
| Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines | [1]C Dirk Keene, [2]Martin Darvas, [3]Brian Kraemer, [4]Denny Liggitt, [5]Christina J. Sigurdson, [6]Warren Ladiges [Full author list] | Pathobiology of aging & age related diseases [curation] | DOI: 10.3402/PBA.V6.32397
PubMed: 27317189 | Alzheimer's disease [curation] | 2016-06-16 |
| Polymorphism of Amyloid Fibrils In Vivo | [1]Karthikeyan Annamalai, [2]Karl-Heinz Gührs, [3]Rolf Koehler, [4]Matthias Schmidt, [5]Henri Michel, [6]Cornelia Loos, [7]Patricia M Gaffney, [8]Christina J. Sigurdson, [9]Ute Hegenbart, [10]Stefan Schönland, [11]Marcus Fändrich [Full author list] | Angewandte Chemie International Edition [curation] | DOI: 10.1002/ANIE.201511524
PubMed: 26954430 | | 2016-03-08 |
| Cross-species transmission of CWD prions | [1]Timothy D Kurt, [2]Christina J. Sigurdson [Full author list] | Prion [curation] | DOI: 10.1080/19336896.2015.1118603
PubMed: 26809254 | prion protein family [curation] | 2016-01-25 |
| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | [1]Daniel J. Klionsky, [2]Kotb Abdelmohsen, [3]Akihisa Abe, [4]Md Joynal Abedin, [5]Hagai Abeliovich, [6]Abraham Acevedo-Arozena, [7]Hiroaki Adachi, [8]Christopher M Adams, [9]Peter D Adams, [10]Khosrow Adeli, ..., [1928]Andriy Sibirny, [1929]Valentina Sica, [1930]Christina J. Sigurdson, [1931]Einar M Sigurdsson, [1932]Puran Singh Sijwali, ... [Full author list] | Autophagy [curation] | DOI: 10.1080/15548627.2015.1100356
PubMed: 26799652 | cell biology [curation]; autophagy [curation] | 2016-01-02 |
| A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates | [1]Hamid Shirani, [2]Mathieu Linares, [3]Christina J. Sigurdson, [4]Mikael Lindgren, [5]Patrick Norman, [6]K Peter R Nilsson [Full author list] | Chemistry—A European Journal [curation] | DOI: 10.1002/CHEM.201502999
PubMed: 26388448 | | 2015-09-21 |
| Human prion protein sequence elements impede cross-species chronic wasting disease transmission | [1]Timothy D Kurt, [2]Lin Jiang, [3]Natalia Fernández-Borges, [4]Cyrus Bett, [5]Jun Liu, [6]Tom Yang, [7]Terry R. Spraker, [8]Joaquín Castilla, [9]David Eisenberg, [10]Qingzhong Kong, [11]Christina J. Sigurdson [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI82647
PubMed: 25961458 | chronic wasting disease [curation] | 2015-05-11 |
| Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death | [1]Nobuhiko Hiramatsu, [2]Wei-Chieh Chiang, [3]Timothy D Kurt, [4]Christina J. Sigurdson, [5]Jonathan H Lin [Full author list] | The American Journal of Pathology [curation] | DOI: 10.1016/J.AJPATH.2015.03.009
PubMed: 25956028 | cell death [curation] | 2015-05-05 |
| Human prion protein sequence elements impede cross-species chronic wasting disease transmission | [1]Timothy D Kurt, [2]Lin Jiang, [3]Natalia Fernández-Borges, [4]Cyrus Bett, [5]Jun Liu, [6]Tom Yang, [7]Terry R. Spraker, [8]Joaquín Castilla, [9]David Eisenberg, [10]Qingzhong Kong, [11]Christina J. Sigurdson [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI79408
PubMed: 25705888 | chronic wasting disease [curation]; prion protein family [curation] | 2015-02-23 |
| Proteomic analysis of highly prevalent amyloid A amyloidosis endemic to endangered island foxes | [1]Patricia M Gaffney, [2]Denise M Imai, [3]Deana L Clifford, [4]Majid Ghassemian, [5]Roman Sasik, [6]Aaron N Chang, [7]Timothy D O'Brien, [8]Judith Coppinger, [9]Margarita Trejo, [10]Eliezer Masliah, [11]Linda Munson, [12]Christina J. Sigurdson [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0113765
PubMed: 25429466 | | 2014-11-26 |
| Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats | [1]Patricia M Gaffney, [2]Bradd Barr, [3]Joan D Rowe, [4]Cyrus Bett, [5]Ioannis Drygiannakis, [6]Federico Giannitti, [7]Margarita Trejo, [8]Majid Ghassemian, [9]Patrice Martin, [10]Eliezer Masliah, [11]Christina J. Sigurdson [Full author list] | FASEB Journal [curation] | DOI: 10.1096/FJ.14-256081
PubMed: 25422367 | stillbirth [curation]; AA amyloidosis [curation] | 2014-11-24 |
| Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands | [1]Karin Magnusson, [2]Rozalyn Simon, [3]Daniel Sjölander, [4]Christina J. Sigurdson, [5]Per Hammarstrom, [6]K Peter R Nilsson [Full author list] | Prion [curation] | DOI: 10.4161/PRI.29239
PubMed: 25495506 | prion protein family [curation] | 2014-11-01 |
| A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC. | [1]Timothy D Kurt, [2]Lin Jiang, [3]Cyrus Bett, [4]David Eisenberg, [5]Christina J. Sigurdson [Full author list] | Journal of Biological Chemistry [curation] | DOI: 10.1074/JBC.M114.549030
PubMed: 24596090 | prion protein family [curation] | 2014-03-04 |
| Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC | [1]Timothy D Kurt, [2]Cyrus Bett, [3]Natalia Fernández-Borges, [4]Shivanjali Joshi-Barr, [5]Simone Hornemann, [6]Thomas Rülicke, [7]Joaquín Castilla, [8]Kurt Wüthrich, [9]Adriano Aguzzi, [10]Christina J. Sigurdson [Full author list] | Journal of Neuroscience [curation] | DOI: 10.1523/JNEUROSCI.4636-13.2014
PubMed: 24431459 | prion protein family [curation] | 2014-01-01 |
| De novo prion aggregates trigger autophagy in skeletal muscle | [1]Shivanjali Joshi-Barr, [2]Cyrus Bett, [3]Wei-Chieh Chiang, [4]Margarita Trejo, [5]Hans H Goebel, [6]Beata Sikorska, [7]Paweł P. Liberski, [8]Alex Raeber, [9]Jonathan H Lin, [10]Eliezer Masliah, [11]Christina J. Sigurdson [Full author list] | Journal of Virology [curation] | DOI: 10.1128/JVI.02279-13
PubMed: 24307586 | autophagy [curation]; prion protein family [curation] | 2013-12-04 |
| The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates | [1]Therése Klingstedt, [2]Hamid Shirani, [3]K O Andreas Åslund, [4]Nigel J Cairns, [5]Christina J. Sigurdson, [6]Michel Goedert, [7]K Peter R Nilsson [Full author list] | Chemistry—A European Journal [curation] | DOI: 10.1002/CHEM.201301463
PubMed: 23780508 | | 2013-06-18 |
| Defining the conformational features of anchorless, poorly neuroinvasive prions | [1]Cyrus Bett, [2]Tim D Kurt, [3]Melanie Lucero, [4]Margarita Trejo, [5]Annemieke J Rozemuller, [6]Qingzhong Kong, [7]K Peter R Nilsson, [8]Eliezer Masliah, [9]Michael B Oldstone, [10]Christina J. Sigurdson [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1003280
PubMed: 23637596 | prion protein family [curation] | 2013-01-01 |
| Mucosal transmission and pathogenesis of chronic wasting disease in ferrets | [1]Matthew R Perrott, [2]Christina J. Sigurdson, [3]Gary L Mason, [4]Edward A. Hoover [Full author list] | Journal of General Virology [curation] | DOI: 10.1099/VIR.0.046110-0
PubMed: 23100363 | pathogenesis [curation]; chronic wasting disease [curation] | 2012-10-24 |
| Aminonaphthalene 2-cyanoacrylate (ANCA) probes fluorescently discriminate between amyloid-β and prion plaques in brain | [1]Kevin Cao, [2]Mona Farahi, [3]Marianna Dakanali, [4]Willy M Chang, [5]Christina J. Sigurdson, [6]Emmanuel A Theodorakis, [7]Jerry Yang [Full author list] | Journal of the American Chemical Society [curation] | DOI: 10.1021/JA3063698
PubMed: 22866977 | prion protein family [curation] | 2012-08-22 |
| Experimental oral transmission of chronic wasting disease to reindeer (Rangifer tarandus tarandus) | [1]Gordon B Mitchell, [2]Christina J. Sigurdson, [3]Katherine I. O'Rourke, [4]James Algire, [5]Noel P Harrington, [6]Ines Walther, [7]Terry R. Spraker, [8]Aru Balachandran [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0039055
PubMed: 22723928 | Rangifer tarandus [curation]; chronic wasting disease [curation]; mountain reindeer [curation] | 2012-06-18 |
| Structure of the β2-α2 loop and interspecies prion transmission | [1]Cyrus Bett, [2]Natalia Fernández-Borges, [3]Timothy D Kurt, [4]Melanie Lucero, [5]K Peter R Nilsson, [6]Joaquín Castilla, [7]Christina J. Sigurdson [Full author list] | FASEB Journal [curation] | DOI: 10.1096/FJ.11-200923
PubMed: 22490928 | prion protein family [curation] | 2012-04-09 |
| Prion infection promotes extensive accumulation of α-synuclein in aged human α-synuclein transgenic mice | [1]Eliezer Masliah, [2]Edward Rockenstein, [3]Chandra Inglis, [4]Anthony Adame, [5]Cyrus Bett, [6]Melanie Lucero, [7]Christina J. Sigurdson [Full author list] | Prion [curation] | DOI: 10.4161/PRI.19806
PubMed: 22460692 | prion protein family [curation]; Synuclein [curation] | 2012-04-01 |
| PK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrP | [1]Gustavo Sajnani, [2]Christopher J Silva, [3]Adriana Ramos, [4]Miguel A Pastrana, [5]Bruce Onisko, [6]Melissa L Erickson, [7]Elizabeth M Antaki, [8]Irina Dynin, [9]Ester Vázquez-Fernández, [10]Christina J. Sigurdson, [11]John Mark Carter, [12]Jesús R Requena [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1002547
PubMed: 22396643 | | 2012-03-01 |
| Biochemical properties of highly neuroinvasive prion strains | [1]Cyrus Bett, [2]Shivanjali Joshi-Barr, [3]Melanie Lucero, [4]Margarita Trejo, [5]Paweł P. Liberski, [6]Jeffery W. Kelly, [7]Eliezer Masliah, [8]Christina J. Sigurdson [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1002522
PubMed: 22319450 | prion protein family [curation] | 2012-02-01 |
| Evidence for distinct chronic wasting disease (CWD) strains in experimental CWD in ferrets | [1]Matthew R Perrott, [2]Christina J. Sigurdson, [3]Gary L Mason, [4]Edward A. Hoover [Full author list] | Journal of General Virology [curation] | DOI: 10.1099/VIR.0.035006-0
PubMed: 21918005 | chronic wasting disease [curation] | 2011-09-14 |
| Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein | [1]Christina J. Sigurdson, [2]Shivanjali Joshi-Barr, [3]Cyrus Bett, [4]Olivia Winson, [5]Giuseppe Manco, [6]Petra Schwarz, [7]Thomas Rülicke, [8]K Peter R Nilsson, [9]Ilan Margalith, [10]Alex Raeber, [11]David Peretz, [12]Simone Hornemann, [13]Kurt Wüthrich, [14]Adriano Aguzzi [Full author list] | Journal of Neuroscience [curation] | DOI: 10.1523/JNEUROSCI.3504-11.2011
PubMed: 21957246 | prion protein family [curation] | 2011-09-01 |
| ANCA: A Family of Fluorescent Probes that Bind and Stain Amyloid Plaques in Human Tissue | [1]Willy M Chang, [2]Marianna Dakanali, [3]Christina C Capule, [4]Christina J. Sigurdson, [5]Jerry Yang, [6]Emmanuel A Theodorakis [Full author list] | ACS Chemical Neuroscience [curation] | DOI: 10.1021/CN200018V
PubMed: 21743829 | | 2011-05-01 |
| Tracking protein aggregate interactions | [1]Christina J. Sigurdson, [2]Jason Bartz, [3]K Peter R Nilsson [Full author list] | Prion [curation] | DOI: 10.4161/PRI.5.2.16173
PubMed: 21597336 | | 2011-04-01 |
| Sheep with scrapie and mastitis transmit infectious prions through the milk | [1]Ciriaco Ligios, [2]Maria Giovanna Cancedda, [3]Antonello Carta, [4]Cinzia Santucciu, [5]Caterina Maestrale, [6]Francesca Demontis, [7]Mariangela Saba, [8]Cristiana Patta, [9]James C DeMartini, [10]Adriano Aguzzi, [11]Christina J. Sigurdson [Full author list] | Journal of Virology [curation] | DOI: 10.1128/JVI.02022-10
PubMed: 21084475 | prion protein family [curation] | 2010-11-17 |
| Cell-to-cell transmission of non-prion protein aggregates | [1]Seung-Jae Lee, [2]Paula Desplats, [3]Christina J. Sigurdson, [4]Igor Tsigelny, [5]Eliezer Masliah [Full author list] | Nature Reviews Neurology [curation] | DOI: 10.1038/NRNEUROL.2010.145
PubMed: 21045796 | prion protein family [curation] | 2010-10-12 |
| Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication | [1]Jill Wegrzyn, [2]Steven J Bark, [3]Lydiane Funkelstein, [4]Charles Mosier, [5]Angel Yap, [6]Parsa Kazemi-Esfarjani, [7]Albert R La Spada, [8]Christina J. Sigurdson, [9]Daniel T O'Connor, [10]Vivian Hook [Full author list] | Journal of Proteome Research [curation] | DOI: 10.1021/PR1003104
PubMed: 20695487 | | 2010-10-01 |
| Prion strain interactions are highly selective | [1]K Peter R Nilsson, [2]Shivanjali Joshi-Barr, [3]Olivia Winson, [4]Christina J. Sigurdson [Full author list] | Journal of Neuroscience [curation] | DOI: 10.1523/JNEUROSCI.2417-10.2010
PubMed: 20826672 | prion protein family [curation] | 2010-09-01 |
| Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein | [1]Malin K Sandberg, [2]Huda Al-Doujaily, [3]Christina J. Sigurdson, [4]Markus Glatzel, [5]Catherine O'Malley, [6]Caroline Powell, [7]Emmanuel A. Asante, [8]Jacqueline M Linehan, [9]Sebastian Brandner, [10]Jonathan D F Wadsworth, [11]John Collinge [Full author list] | Journal of General Virology [curation] | DOI: 10.1099/VIR.0.024380-0
PubMed: 20610667 | chronic wasting disease [curation]; prion protein family [curation]; overexpression [curation] | 2010-07-07 |
| A molecular switch controls interspecies prion disease transmission in mice | [1]Christina J. Sigurdson, [2]K Peter R Nilsson, [3]Simone Hornemann, [4]Giuseppe Manco, [5]Natalia Fernández-Borges, [6]Petra Schwarz, [7]Joaquín Castilla, [8]Kurt Wüthrich, [9]Adriano Aguzzi [Full author list] | Journal of Clinical Investigation [curation] | DOI: 10.1172/JCI42051
PubMed: 20551516 | prion protein family [curation] | 2010-06-14 |
| Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses | [1]Andreas Aslund, [2]Christina J. Sigurdson, [3]Therése Klingstedt, [4]Stefan Grathwohl, [5]Tristan Bolmont, [6]Dara L Dickstein, [7]Eirik Glimsdal, [8]Stefan Prokop, [9]Mikael Lindgren, [10]Peter Konradsson, [11]David M. Holtzman, [12]Patrick R Hof, [13]Frank L Heppner, [14]Samuel Gandy, [15]Mathias Jucker, [16]Adriano Aguzzi, [17]Per Hammarström, [18]K Peter R Nilsson [Full author list] | ACS Chemical Biology [curation] | DOI: 10.1021/CB900112V
PubMed: 19624097 | optical imaging [curation] | 2009-08-01 |
| Bacterial colitis increases susceptibility to oral prion disease | [1]Christina J. Sigurdson, [2]Mathias Heikenwalder, [3]Giuseppe Manco, [4]Manja Barthel, [5]Petra Schwarz, [6]Bärbel Stecher, [7]Nike J Krautler, [8]Wolf-Dietrich Hardt, [9]Burkhardt Seifert, [10]Andrew J S MacPherson, [11]Irène Corthesy, [12]Adriano Aguzzi [Full author list] | Journal of Infectious Diseases [curation] | DOI: 10.1086/595791
PubMed: 19072552 | colitis [curation]; prion protein family [curation] | 2009-01-01 |
| De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis | [1]Christina J. Sigurdson, [2]K Peter R Nilsson, [3]Simone Hornemann, [4]Mathias Heikenwalder, [5]Giuseppe Manco, [6]Petra Schwarz, [7]David Ott, [8]Thomas Rülicke, [9]Paweł P. Liberski, [10]Christian Julius, [11]Jeppe Falsig, [12]Lothar Stitz, [13]Kurt Wüthrich, [14]Adriano Aguzzi [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.0810680105
PubMed: 19073920 | transmissible spongiform encephalopathy [curation] | 2008-12-10 |
| The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes | [1]Magdalini Polymenidou, [2]Rita Moos, [3]Mike Scott, [4]Christina J. Sigurdson, [5]Yong-Zhong Shi, [6]Bill Yajima, [7]Iva Hafner-Bratkovic, [8]Roman Jerala, [9]Simone Hornemann, [10]Kurt Wüthrich, [11]Anne Bellon, [12]Martin Vey, [13]Graciela Garen, [14]Michael N G James, [15]Nat Kav, [16]Adriano Aguzzi [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0003872
PubMed: 19060956 | antibody [curation]; prion protein family [curation] | 2008-12-08 |
| Lymphotoxin-Dependent Prion Replication in Inflammatory Stromal Cells of Granulomas | [1]Mathias Heikenwalder, [2]Michael O. Kurrer, [3]Ilan Margalith, [4]Jan Kranich, [5]Nicolas Zeller, [6]Johannes Haybaeck, [7]Magdalini Polymenidou, [8]Matthias S Matter, [9]Juliane Bremer, [10]Walker S. Jackson, [11]Susan Lindquist, [12]Christina J. Sigurdson, [13]Adriano Aguzzi [Full author list] | Immunity [curation] | DOI: 10.1016/J.IMMUNI.2008.10.014
PubMed: 19100703 | inflammation [curation] | 2008-12-01 |
| A prion disease of cervids: chronic wasting disease | [1]Christina J. Sigurdson [Full author list] | Veterinary Research [curation] | DOI: 10.1051/VETRES:2008018
PubMed: 18381058 | chronic wasting disease [curation]; prion protein family [curation] | 2008-04-03 |
| Molecular mechanisms of prion pathogenesis | [1]Adriano Aguzzi, [2]Christina J. Sigurdson, [3]Mathias Heikenwaelder [Full author list] | Annual Review of Pathology: Mechanisms of Disease [curation] | DOI: 10.1146/ANNUREV.PATHMECHDIS.3.121806.154326
PubMed: 18233951 | pathogenesis [curation]; prion protein family [curation] | 2008-01-01 |
| Prion strain discrimination using luminescent conjugated polymers | [1]Christina J. Sigurdson, [2]K Peter R Nilsson, [3]Simone Hornemann, [4]Giuseppe Manco, [5]Magdalini Polymenidou, [6]Petra Schwarz, [7]Mario Leclerc, [8]Per Hammarström, [9]Kurt Wüthrich, [10]Adriano Aguzzi [Full author list] | Nature Methods [curation] | DOI: 10.1038/NMETH1131
PubMed: 18026110 | | 2007-11-18 |
| Chronic wasting disease. | [1]Christina J. Sigurdson, [2]Adriano Aguzzi [Full author list] | Biochimica et Biophysica Acta [curation] | DOI: 10.1016/J.BBADIS.2006.10.010
PubMed: 17223321 | chronic wasting disease [curation] | 2006-10-18 |
| Strain fidelity of chronic wasting disease upon murine adaptation | [1]Christina J. Sigurdson, [2]Giuseppe Manco, [3]Petra Schwarz, [4]Paweł P. Liberski, [5]Edward A. Hoover, [6]Simone Hornemann, [7]Magdalini Polymenidou, [8]Michael W. Miller, [9]Markus Glatzel, [10]Adriano Aguzzi [Full author list] | Journal of Virology [curation] | DOI: 10.1128/JVI.01120-06
PubMed: 17020952 | chronic wasting disease [curation] | 2006-10-04 |
| Infectious prions in the saliva and blood of deer with chronic wasting disease | [1]Candace K. Mathiason, [2]Jenny G Powers, [3]Sallie J Dahmes, [4]David A Osborn, [5]Karl V Miller, [6]Robert J Warren, [7]Gary L Mason, [8]Sheila A Hays, [9]Jeanette Hayes-Klug, [10]Davis M. Seelig, [11]Margaret A. Wild, [12]Lisa L. Wolfe, [13]Terry R. Spraker, [14]Michael W. Miller, [15]Christina J. Sigurdson, [16]Glenn C. Telling, [17]Edward A. Hoover [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.1132661
PubMed: 17023660 | saliva [curation]; chronic wasting disease [curation]; prion protein family [curation] | 2006-10-01 |
| Prions in skeletal muscles of deer with chronic wasting disease | [1]Rachel C Angers, [2]Shawn R Browning, [3]Tanya S Seward, [4]Christina J. Sigurdson, [5]Michael W. Miller, [6]Edward A. Hoover, [7]Glenn C. Telling [Full author list] | Science [curation] | DOI: 10.1126/SCIENCE.1122864
PubMed: 16439622 | chronic wasting disease [curation]; prion protein family [curation] | 2006-01-26 |
| PrPSc in mammary glands of sheep affected by scrapie and mastitis | [1]Ciriaco Ligios, [2]Christina J. Sigurdson, [3]Cinzia Santucciu, [4]Gabriella Carcassola, [5]Giuseppe Manco, [6]Massimo Basagni, [7]Caterina Maestrale, [8]Maria Giovanna Cancedda, [9]Laura Madau, [10]Adriano Aguzzi [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM1105-1137
PubMed: 16270061 | | 2005-11-01 |
| Reconstructing prions: fibril assembly from simple yeast to complex mammals | [1]Christina J. Sigurdson, [2]Magdalini Polymenidou, [3]Adriano Aguzzi [Full author list] | Neurodegenerative Diseases [curation] | DOI: 10.1159/000086425
PubMed: 16908997 | prion protein family [curation] | 2005-01-01 |
| Letters to the Editor | [1]Christina J. Sigurdson, [2]Markus Glatzel, [3]Adriano Aguzzi [Full author list] | Veterinary Pathology [curation] | DOI: 10.1354/VP.42-1-107
PubMed: 15657284 | letter to the editor [curation] | 2005-01-01 |
| Antiprion immunotherapy: to suppress or to stimulate? | [1]Adriano Aguzzi, [2]Christina J. Sigurdson [Full author list] | Nature Reviews Immunology [curation] | DOI: 10.1038/NRI1437
PubMed: 15343371 | immunotherapy [curation] | 2004-09-01 |
| Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration | [1]Mathias Heikenwalder, [2]Magdalini Polymenidou, [3]Tobias Junt, [3-Q46152343]Tobias Junt, [4]Christina J. Sigurdson, [5]Hermann Wagner, [6]Shizuo Akira, [7]Rolf M. Zinkernagel, [8]Adriano Aguzzi [Full author list] | Nature Medicine [curation] | DOI: 10.1038/NM987
PubMed: 14745443 | immunosuppression [curation] | 2004-01-25 |
| Other animal prion diseases | [1]Christina J. Sigurdson, [2]Michael W. Miller [Full author list] | British Medical Bulletin [curation] | DOI: 10.1093/BMB/66.1.199
PubMed: 14522860 | prion protein family [curation] | 2003-01-01 |
| PrP(CWD) lymphoid cell targets in early and advanced chronic wasting disease of mule deer | [1]Christina J. Sigurdson, [2]Carolina Barillas-Mury, [3]Michael W. Miller, [4]Bruno Oesch, [5]Lucien J M van Keulen, [6]Jan P M Langeveld, [7]Edward A. Hoover [Full author list] | Journal of General Virology [curation] | DOI: 10.1099/0022-1317-83-10-2617
PubMed: 12237446 | chronic wasting disease [curation] | 2002-10-01 |
| Preclinical diagnosis of chronic wasting disease in captive mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus) using tonsillar biopsy. | [1]Margaret A. Wild, [2]Terry R. Spraker, [3]Christina J. Sigurdson, [4]Katherine I. O'Rourke, [5]Michael W. Miller [Full author list] | Journal of General Virology [curation] | DOI: 10.1099/0022-1317-83-10-2629
PubMed: 12237447 | white-tailed deer [curation]; mule deer [curation]; chronic wasting disease [curation] | 2002-10-01 |