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Luis A. Pardo

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Listed Publications

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50 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.[1]Lien Moreels, [2]Steve Peigneur, [3]Diogo T Galan, [4]Edwin De Pauw, [5]Lászlo Béress, [6]Etienne Waelkens, [7]Luis A. Pardo, [8]Loic Quinton, [9]Jan Tytgat [Full author list]Marine Drugs [curation]DOI: 10.3390/MD15090287
PubMed: 28902151
2017-09-13
Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer[1]Stine Pedersen, [2]Ivana Novak, [3]Frauke Alves, [4]Albrecht Schwab, [5]Luis A. Pardo [Full author list]BioEssays [curation]DOI: 10.1002/BIES.201600253
PubMed: 28440551
2017-04-25
The electric fence to cell-cycle progression: Do local changes in membrane potential facilitate disassembly of the primary cilium?: Timely and localized expression of a potassium channel may set the conditions that allow retraction of the primary ci[1]Diana Urrego, [2]Araceli Sánchez, [3]Adam P Tomczak, [4]Luis A. Pardo [Full author list]BioEssays [curation]DOI: 10.1002/BIES.201600190
PubMed: 28370099
2017-03-30
A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore[1]Adam P Tomczak, [2]Jorge Fernández-Trillo, [3]Shashank Bharill, [4]Ferenc Papp, [5]György Panyi, [6]Walter Stühmer, [7]Ehud Y. Isacoff, [8]Luis A. Pardo [Full author list]The Journal of General Physiology [curation]DOI: 10.1085/JGP.201611742
PubMed: 28360219
2017-03-30
In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1.[1]Joanna Napp, [2]Luis A. Pardo, [3]Franziska Hartung, [4]Lutz F Tietze, [5]Walter Stühmer, [6]Frauke Alves [Full author list]European Biophysics Journal [curation]DOI: 10.1007/S00249-016-1152-Z
PubMed: 27444284
xenograft [curation]; tumour xenograft [curation]2016-07-21
Ion channels, transporters and cancer ("INCA2015"): an international meeting in honor of Prof. Dr. Walter Stühmer.[1]Mustafa B A Djamgoz, [2]Luis A. Pardo [Full author list]European Biophysics Journal [curation]DOI: 10.1007/S00249-016-1153-Y
PubMed: 27435254
2016-07-20
Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin[1]Franziska Hartung, [2]Luis A. Pardo [Full author list]European Biophysics Journal [curation]DOI: 10.1007/S00249-016-1149-7
PubMed: 27350552
2016-06-27
Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium[1]Araceli Sánchez, [2]Diana Urrego, [3]Luis A. Pardo [Full author list]EMBO Reports [curation]DOI: 10.15252/EMBR.201541082
PubMed: 27113750
2016-04-20
Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells[1]Diana Urrego, [2]Naira Movsisyan, [3]Roser Ufartes, [4]Luis A. Pardo [Full author list]Cell Cycle [curation]DOI: 10.1080/15384101.2016.1138187
PubMed: 27029528
2016-03-01
SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments[1]Sabine Martin, [2]Marcio Lazzarini, [3]Christian Dullin, [4]Saju Balakrishnan, [5]Felipe V. Gomes, [6]Milena Ninkovic, [7]Ahmed El Hady, [8]Luis A. Pardo, [9]Walter Stühmer, [10]Elaine Del Bel, [11]Elaine Del-Bel [Full author list]Molecular Neurobiology [curation]DOI: 10.1007/S12035-015-9680-6
PubMed: 26803493
cognitive dysfunction [curation]; overexpression [curation]2016-01-23
Kv10.1 K(+) channel: from physiology to cancer[1]Halima Ouadid-Ahidouch, [2]Ahmed Ahidouch, [3]Luis A. Pardo [Full author list]Pfluegers Archiv [curation]DOI: 10.1007/S00424-015-1784-3
PubMed: 26743871
2016-01-08
Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes[1]Fernanda Ramos Gomes, [2]Vincenzo Romaniello, [3]Araceli Sánchez, [4]Claudia Weber, [5]Pratibha Narayanan, [6]Maryna Psol, [7]Luis A. Pardo [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M115.668749
PubMed: 26518875
2015-10-30
CD133 Expression Is Not Synonymous to Immunoreactivity for AC133 and Fluctuates throughout the Cell Cycle in Glioma Stem-Like Cells[1]Alonso Barrantes-Freer, [2]Mirjam Renovanz, [3]Marcus Eich, [4]Alina Braukmann, [5]Bettina Sprang, [6]Pavel Spirin, [7]Luis A. Pardo, [8]Alf Giese, [9]Ella L Kim [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0130519
PubMed: 26086074
2015-06-18
Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains[1]Éva Lörinczi, [2]Juan Camilo Gómez-Posada, [3]Pilar de la Peña, [4]Adam P Tomczak, [5]Jorge Fernández-Trillo, [6]Ulrike Leipscher, [7]Walter Stühmer, [8]Francisco Barros, [9]Luis A. Pardo [Full author list]Nature Communications [curation]DOI: 10.1038/NCOMMS7672
PubMed: 25818916
voltage [curation]2015-03-30
KV 10.1 opposes activity-dependent increase in Ca²⁺ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse[1]Lena Sünke Mortensen, [2]Hartmut Schmidt, [3]Zohreh Farsi, [4]Alonso Barrantes-Freer, [5]María E Rubio, [6]Roser Ufartes, [7]Jens Eilers, [8]Takeshi Sakaba, [9]Walter Stühmer, [10]Luis A. Pardo [Full author list]Journal of Physiology [curation]DOI: 10.1113/JPHYSIOL.2014.281600
PubMed: 25556795
Purkinje cell [curation]; Potassium voltage-gated channel, subfamily H (eag-related), member 1 [curation]2014-11-25
Potassium channels in cell cycle and cell proliferation[1]Diana Urrego, [2]Adam P Tomczak, [3]Farrah Zahed, [4]Walter Stühmer, [5]Luis A. Pardo [Full author list]Philosophical Transactions of the Royal Society B [curation]DOI: 10.1098/RSTB.2013.0094
PubMed: 24493742
cell cycle [curation]; cell population proliferation [curation]; potassium channel [curation]; neoplasm [curation]; modelling biological systems [curation]2014-03-19
The roles of K(+) channels in cancer[1]Luis A. Pardo, [2]Walter Stühmer [Full author list]Nature Reviews Cancer [curation]DOI: 10.1038/NRC3635
PubMed: 24336491
2013-12-12
Hippocampal ether-à-go-go1 potassium channels blockade: effects in the startle reflex and prepulse inhibition[1]A C Issy, [2]J R Fonseca, [3]Luis A. Pardo, [4]W Stühmer, [5]Elaine Del Bel, [6]Elaine Del-Bel [Full author list]Neuroscience Letters [curation]DOI: 10.1016/J.NEULET.2013.11.026
PubMed: 24284010
2013-11-24
KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons[1]Aura M Jiménez-Garduño, [2]Miso Mitkovski, [3]Ioannis Alexopoulos, [4]Araceli Sánchez, [5]Walter Stühmer, [6]Luis A. Pardo, [7]Alicia Ortega [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/J.BBAMEM.2013.11.007
PubMed: 24269539
2013-11-22
PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1.[1]Solveig Herrmann, [2]Milena Ninkovic, [3]Tobias Kohl, [4]Luis A. Pardo [Full author list]Frontiers in Physiology [curation]DOI: 10.3389/FPHYS.2013.00201
PubMed: 23966943
2013-08-14
Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia[1]Alonso Barrantes-Freer, [2]Ella Kim, [3]Joanna Bielanska, [4]Alf Giese, [5]Lena Sünke Mortensen, [6]Walter J Schulz-Schaeffer, [7]Christine Stadelmann, [8]Wolfgang Brück, [9]Luis A. Pardo [Full author list]Journal of Neuropathology & Experimental Neurology [curation]DOI: 10.1097/NEN.0B013E31828AFDBD
PubMed: 23481707
phenotype [curation]; neuroglia [curation]2013-04-01
Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice[1]Roser Ufartes, [2]Tomasz Schneider, [3]Lena Sünke Mortensen, [4]Camino de Juan Romero, [5]Klaus Hentrich, [6]Hendrik Knoetgen, [7]Vadim Beilinson, [8]Wiebke Moebius, [9]Victor Tarabykin, [10]Frauke Alves, [11]Luis A. Pardo, [12]J Nicholas P Rawlins, [13]Walter Stuehmer [Full author list]Human Molecular Genetics [curation]DOI: 10.1093/HMG/DDT076
PubMed: 23424202
knockout mouse [curation]2013-02-18
TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells[1]María Ll Valero, [2]Fernanda Mello de Queiroz, [3]Walter Stühmer, [4]Félix Viana, [5]Luis A. Pardo [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0051825
PubMed: 23251635
lithium-ion battery [curation]2012-12-14
Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1.[1]Solveig Herrmann, [2]Milena Ninkovic, [3]Tobias Kohl, [4]Éva Lörinczi, [5]Luis A. Pardo [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M112.372540
PubMed: 23144454
2012-11-09
Physical and functional interaction of KV10.1 with Rabaptin-5 impacts ion channel trafficking[1]Milena Ninkovic, [2]Miso Mitkovski, [3]Tobias Kohl, [4]Walter Stühmer, [5]Luis A. Pardo [Full author list]FEBS Letters [curation]DOI: 10.1016/J.FEBSLET.2012.07.055
PubMed: 22841712
vesicle-mediated transport [curation]; Potassium voltage-gated channel subfamily H member 1 [curation]; Rabaptin, RAB GTPase binding effector protein 1 [curation]2012-07-25
ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways.[1]Paulina Carriba, [2]Luis A. Pardo, [3]Arnaldo Parra-Damas, [4]Mathieu P Lichtenstein, [5]Carlos A. Saura, [6]Aurora Pujol, [7]Roser Masgrau, [8]Elena Galea [Full author list]Glia [curation]DOI: 10.1002/GLIA.22352
PubMed: 22593004
norepinephrine [curation]; astrocyte [curation]2012-05-16
Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications[1]Sofía Tirados Menéndez, [2]María Angeles Villaronga, [3]Juan Pablo Rodrigo, [4]Saúl Álvarez-Teijeiro, [5]Darío García-Carracedo, [6]Rocío G Urdinguio, [7]Mario F Fraga, [8]Luis A. Pardo, [9]Cristina Gutiérrez Viloria, [10]Carlos Suárez, [11]Juana María García-Pedrero [Full author list]Journal of Molecular Medicine [curation]DOI: 10.1007/S00109-012-0893-0
PubMed: 22466864
head and neck cancer [curation]; head and neck carcinoma [curation]; neck cancer [curation]2012-03-31
Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy[0]Luis A. Pardo, [1]Pardo LA, [2]Gómez-Varela D, [3]Major F, [4]Sansuk K, [5]Leurs R, [6]Downie BR, [7]Tietze LF, [8]Stühmer W [Full author list]Current Medicinal Chemistry [curation]DOI: 10.2174/092986712798992011
PubMed: 22204340
cancer diagnosis [curation]2012-01-01
Ether-à-go-go 1 (Eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion[1]N R Ferreira, [2]Miso Mitkovski, [3]W Stühmer, [4]Luis A. Pardo, [5]Elaine Del-Bel, [6]Elaine Del Bel [Full author list]Neurotoxicity Research [curation]DOI: 10.1007/S12640-011-9286-3
PubMed: 22048886
dopamine [curation]2011-11-03
Rapid internalization of the oncogenic K+ channel K(V)10.1.[1]Tobias Kohl, [2]Eva Lörinczi, [3]Luis A. Pardo, [4]Walter Stühmer [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0026329
PubMed: 22022602
2011-10-12
Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody[1]Franziska Hartung, [2]Walter Stühmer, [3]Luis A. Pardo [Full author list]Molecular Cancer [curation]DOI: 10.1186/1476-4598-10-109
PubMed: 21899742
apoptotic process [curation]2011-09-07
Eag1 potassium channels as markers of cervical dysplasia[1]Cindy Sharon Ortiz, [2]Daniel Montante-Montes, [3]Milena Saqui-Salces, [4]Luz María Hinojosa, [5]Armando Gamboa-Dominguez, [6]Elisabeth Hernández-Gallegos, [7]Braulio Martínez-Benítez, [8]María Del Rosario Solís-Pancoatl, [9]Enrique Garcia-Villa, [10]Ana Ramírez, [11]Ricardo Aguilar-Guadarrama, [12]Patricio Gariglio, [13]Luis A. Pardo, [14]Walter Stühmer, [15]Javier Camacho [Full author list]Oncology Reports [curation]DOI: 10.3892/OR.2011.1441
PubMed: 21887469
2011-08-31
Nucleofection induces non-specific changes in the metabolic activity of transfected cells[1]Fernanda Mello de Queiroz, [2]Araceli Sánchez, [3]Jasmin Roya Agarwal, [4]Walter Stühmer, [5]Luis A. Pardo [Full author list]Molecular Biology Reports [curation]DOI: 10.1007/S11033-011-0967-Z
PubMed: 21643953
2011-06-05
A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia[1]Sabrina Grube, [2]Martin F. Gerchen, [3]Bartosz Adamcio, [4]Luis A. Pardo, [5]Sabine Martin, [6]Dörthe Malzahn, [7]Sergi Papiol, [8]Martin Begemann, [9]Katja Ribbe, [10]Heidi Friedrichs, [11]Konstantin A Radyushkin, [12]Michael Müller, [13]Fritz Benseler, [14]Joachim Riggert, [15]Peter Falkai, [16]Heike Bickeböller, [17]Klaus-Armin Nave, [18]Nils Brose, [19]Walter Stühmer, [20]Hannelore Ehrenreich [Full author list]EMBO Molecular Medicine [curation]DOI: 10.1002/EMMM.201100135
PubMed: 21433290
schizophrenia [curation]2011-03-24
Eag 1, Eag 2 and Kcnn3 gene brain expression of isolated reared rats[1]S Martin, [2]Cilene Lino-de-Oliveira, [3]S R L Joca, [4]R Weffort de Oliveira, [5]M B Echeverry, [6]C A Da Silva, [7]Luis A. Pardo, [8]W Stühmer, [9]E D Bel [Full author list]Genes, Brain and Behavior [curation]DOI: 10.1111/J.1601-183X.2010.00632.X
PubMed: 20662937
2010-11-01
K(+) channels as therapeutic targets in oncology[1]Walter Stühmer, [2]Luis A. Pardo [Full author list]Future Medicinal Chemistry [curation]DOI: 10.4155/FMC.10.24
PubMed: 21426201
2010-05-01
The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia[1]Jasmin R Agarwal, [2]Frank Griesinger, [3]Walter Stühmer, [4]Luis A. Pardo [Full author list]Molecular Cancer [curation]DOI: 10.1186/1476-4598-9-18
PubMed: 20105281
leukemia [curation]; acute myeloid leukemia [curation]2010-01-27
Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots[1]David Gómez-Varela, [2]Tobias Kohl, [3]Manuela Schmidt, [4]María E Rubio, [5]Hiroshi Kawabe, [6]Ralf B Nehring, [7]Stephan Schäfer, [8]Walter Stühmer, [9]Luis A. Pardo [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0008858
PubMed: 20111597
quantum dot [curation]2010-01-25
Concept of a selective tumour therapy and its evaluation by near-infrared fluorescence imaging and flat-panel volume computed tomography in mice[1]Frauke Alves, [2]Christian Dullin, [3]Joanna Napp, [4]Jeannine Missbach-Guentner, [5]Katharina Jannasch, [6]Julia Mathejczyk, [7]Luis A. Pardo, [8]Walter Stühmer, [9]Lutz-F Tietze [Full author list]European Journal of Radiology [curation]DOI: 10.1016/J.EJRAD.2009.01.048
PubMed: 19285818
computed tomography [curation]2009-03-13
Ion channels: functional expression and therapeutic potential in cancer. Colloquium on Ion Channels and Cancer[1]Scott P Fraser, [2]Luis A. Pardo [Full author list]EMBO Reports [curation]DOI: 10.1038/EMBOR.2008.75
PubMed: 18451877
2008-05-02
Eag1: an emerging oncological target[1]Luis A. Pardo, [2]Walter Stühmer [Full author list]Cancer Research [curation]DOI: 10.1158/0008-5472.CAN-07-5710
PubMed: 18339837
2008-03-01
Overexpression of Eag1 potassium channels in clinical tumours[1]Bernhard Hemmerlein, [2]Rüdiger M Weseloh, [3]Fernanda Mello de Queiroz, [4]Hendrik Knötgen, [5]Araceli Sánchez, [6]María E Rubio, [7]Sabine Martin, [8]Tessa Schliephacke, [9]Marc Jenke, [10]Heinz-Joachim-Radzun, [11]Walter Stühmer, [12]Luis A. Pardo [Full author list]Molecular Cancer [curation]DOI: 10.1186/1476-4598-5-41
PubMed: 17022810
overexpression [curation]2006-10-05
Ether à go-go potassium channel expression in soft tissue sarcoma patients[1]Fernanda Mello de Queiroz, [2]Guilherme Suarez-Kurtz, [3]Walter Stühmer, [4]Luis A. Pardo [Full author list]Molecular Cancer [curation]DOI: 10.1186/1476-4598-5-42
PubMed: 17022811
2006-01-01
Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences[1]Joanna Napp, [2]Francisco Monje, [3]Walter Stühmer, [4]Luis A. Pardo [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M504228200
PubMed: 15964838
glycosylation [curation]2005-06-17
Role of voltage-gated potassium channels in cancer[1]Luis A. Pardo, [2]C Contreras-Jurado, [3]M Zientkowska, [4]F Alves, [5]W Stühmer [Full author list]Journal of Membrane Biology [curation]DOI: 10.1007/S00232-005-0776-1
PubMed: 16362499
voltage [curation]2005-06-01
Ether a go-go potassium channels as human cervical cancer markers[0]Luis A. Pardo, [1]Luz María Barajas Farias, [2]Deysi Bermúdez Ocaña, [3]Lorenza Díaz, [4]Fernando Larrea, [5]Euclides Avila-Chávez, [6]Adriana Cadena, [7]Luz María Hinojosa, [8]Gerardo Lara, [9]Luis Alberto Villanueva, [10]Carlos Vargas, ... [Full author list]Cancer Research [curation]DOI: 10.1158/0008-5472.CAN-04-1204
PubMed: 15466192
cervix uterine cancer [curation]2004-10-01
Ion channels in health and disease. 83rd Boehringer Ingelheim Fonds International Titisee Conference[1]Niemeyer BA, [2]Mery L, [3]Zawar C, [4]Suckow A, [5]Monje F, [6]Luis A. Pardo, [7]Stuhmer W, [8]Flockerzi V, [9]Markus Hoth [Full author list]EMBO Reports [curation]DOI: 10.1093/EMBO-REPORTS/KVE145
PubMed: 11463739
2001-07-01
Oncogenic potential of EAG K(+) channels[1]Luis A. Pardo, [2]del Camino D, [3]Sánchez A, [4]Alves F, [5]Brüggemann A, [6]Beckh S, [7]Stühmer W [Full author list]The EMBO Journal [curation]DOI: 10.1093/EMBOJ/18.20.5540
PubMed: 10523298
1999-10-01
Demonstration of an inwardly rectifying K+ current component modulated by thyrotropin-releasing hormone and caffeine in GH3 rat anterior pituitary cells[1]Francisco Barros, [2]D del Camino, [3]Luis A. Pardo, [4]T Palomero, [5]Teresa Giráldez Fernández, [6]Pilar de la Peña [Full author list]Pfluegers Archiv [curation]DOI: 10.1007/S004240050491
PubMed: 9359911
1997-12-01
Caffeine enhancement of electrical activity through direct blockade of inward rectifying K+ currents in GH3 rat anterior pituitary cells[0]Luis A. Pardo, [1]F Barros, [2]D del Camino, [3]L A Pardo, [4]P de la Peña [Full author list]Pfluegers Archiv [curation]DOI: 10.1007/BF02207284
PubMed: 8584440
1996-01-01
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