| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking | [1]Mingxun Wang, [2]Jeremy J Carver, [3]Vanessa Phelan, [4]Laura M. Sanchez, [5]Neha Garg, [6]Yao Peng, [7]Don Duy Nguyen, [8]Jeramie D. Watrous, [9]Clifford A Kapono, [10]Tal Luzzatto-Knaan, ..., [109]Danielle VanLeer, [110]Paul Shinn, [111]Ajit Jadhav, [112]Rolf Müller, [113]Katrina M. Waters, ... [Full author list] | Nature Biotechnology [curation] | DOI: 10.1038/NBT.3597
PubMed: 27504778 | biotechnology [curation]; microbiology [curation]; natural product [curation]; data sharing [curation]; data curation [curation]; community curation [curation] | 2016-08-01 |
| Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond | [1]Wesley C Van Voorhis, [2]John H Adams, [3]Roberto Adelfio, [4]Vida Ahyong, [5]Myles H Akabas, [6]Pietro Alano, [7]Aintzane Alday, [8]Yesmalie Alemán Resto, [9]Aishah Alsibaee, [10]Ainhoa Alzualde, ..., [72]Katrin Ingram-Sieber, [73]Maurice A Itoe, [74]Ajit Jadhav, [75]Amornrat Naranuntarat Jensen, [76]Laran T Jensen, ... [Full author list] | PLOS Pathogens [curation] | DOI: 10.1371/JOURNAL.PPAT.1005763
PubMed: 27467575 | malaria [curation]; open-source software [curation]; drug discovery [curation]; data sharing [curation]; open-source drug discovery [curation] | 2016-07-01 |
| Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease | [1]Xin Hu, [2]Jaimee R Compton, [3]Dagmar H Leary, [4]Mark A Olson, [5]Michael S Lee, [6]Jonah Cheung, [7]Wenjuan Ye, [8]Mark Ferrer, [9]Noel Southall, [10]Ajit Jadhav, [11]Elaine M Morazzani, [12]Pamela J Glass, [13]Juan Marugan, [14]Patricia M Legler [Full author list] | Biochemistry [curation] | DOI: 10.1021/ACS.BIOCHEM.5B00992
PubMed: 27030368 | Venezuelan equine encephalitis virus [curation]; equine encephalitis [curation]; Venezuelan equine encephalitis [curation] | 2016-05-31 |
| A potent and selective inhibitor targeting human and murine 12/15-LOX | [1]Michelle M Armstrong, [2]Cody J Freedman, [3]Joo Eun Jung, [4]Yi Zheng, [5]Chakrapani Kalyanaraman, [6]Matthew P. Jacobson, [7]Anton Simeonov, [8]David J Maloney, [9]Klaus van Leyen, [10]Ajit Jadhav, [11]Theodore R Holman [Full author list] | Bioorganic & Medicinal Chemistry [curation] | DOI: 10.1016/J.BMC.2016.01.042
PubMed: 26899595 | | 2016-01-21 |
| A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models | [1]Natalia J Martinez, [2]Ganesha Rai, [3]Adam Yasgar, [4]Wendy A Lea, [5]Hongmao Sun, [6]Yuhong Wang, [7]Diane K Luci, [8]Shyh-Ming Yang, [9]Kana Nishihara, [10]Shunichi Takeda, ..., [17]Menghang Xia, [18]Maurizio Grimaldi, [19]Ajit Jadhav, [20]David J Maloney, [21]Anton Simeonov [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0161486
PubMed: 27570969 | endoplasmic reticulum [curation]; high-throughput screening [curation] | 2016-01-01 |
| AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions | [1]Adam Yasgar, [2]Ajit Jadhav, [3]Anton Simeonov, [4]Nathan P Coussens [Full author list] | Methods in Molecular Biology [curation] | DOI: 10.1007/978-1-4939-3673-1_5
PubMed: 27316989 | high-throughput screening [curation]; protein-protein interaction [curation] | 2016-01-01 |
| Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes | [1]Stuart Schreiber, [2]Joanne D Kotz, [3]Min Li, [4]Jeffrey Aubé, [5]Christopher P Austin, [6]John C Reed, [7]Hugh Rosen, [8]E Lucile White, [9]Larry Sklar, [10]Craig W Lindsley, ..., [24]Frank J Schoenen, [25]Anton Simeonov, [26]Ajit Jadhav, [27]Michael R Jackson, [28]Anthony B Pinkerton, ... [Full author list] | Cell [curation] | DOI: 10.1016/J.CELL.2015.05.023
PubMed: 26046436 | | 2015-06-04 |
| Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays | [1]Jonathan A Lee, [2]Andrew Paul Shinn, [3]Susan Jaken, [4]Sarah Oliver, [5]Francis S Willard, [6]Steven Heidler, [7]Robert B Peery, [8]Jennifer Oler, [9]Shaoyou Chu, [10]Noel Southall, ..., [13]Ruili Huang, [14]Rajarshi Guha, [15]Ajit Jadhav, [16]Karen Cox, [17]Christopher P Austin, ... [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0130796
PubMed: 26177200 | | 2015-01-01 |
| Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation | [1]Jennifer Yeung, [2]Benjamin E Tourdot, [3]Pilar Fernandez-Perez, [4]Joanne Vesci, [5]Jin Ren, [6]Christopher J Smyrniotis, [7]Diane K Luci, [8]Ajit Jadhav, [9]Anton Simeonov, [10]David J Maloney, [11]Theodore R Holman, [12]Steven E McKenzie, [13]Michael Holinstat [Full author list] | Blood [curation] | DOI: 10.1182/BLOOD-2014-05-575878
PubMed: 25100742 | | 2014-08-06 |
| Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies | [1]Ganesha Rai, [2]Netra Joshi, [3]Joo Eun Jung, [4]Yu Liu, [5]Lena Schultz, [6]Adam Yasgar, [7]Steven Perry, [8]Giovanni Diaz, [9]Qiangli Zhang, [10]Victor Kenyon, [11]Ajit Jadhav, [12]Anton Simeonov, [13]Eng H Lo, [14]Klaus van Leyen, [15]David J Maloney, [16]Theodore R Holman [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM401915R
PubMed: 24684213 | | 2014-05-13 |
| Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy | [1]Rachel Abbotts, [2]Rosalyn Jewell, [3]Jérémie Nsengimana, [4]David J Maloney, [5]Anton Simeonov, [6]Claire Seedhouse, [7]Faye Elliott, [8]Jon Laye, [9]Christy Walker, [10]Ajit Jadhav, [11]Anna Grabowska, [12]Graham Ball, [13]Poulam M Patel, [14]Julia A Newton Bishop, [15]David M Wilson, [16]Srinivasan Madhusudan, [2-Q64683225]Graham Ball [Full author list] | Oncotarget [curation] | DOI: 10.18632/ONCOTARGET.1926
PubMed: 24830350 | | 2014-05-01 |
| High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells | [1]Lesley Mathews Griner, [2]Rajarshi Guha, [3]Andrew Paul Shinn, [4]Ryan M Young, [5]Jonathan M Keller, [6]Dongbo Liu, [7]Ian S Goldlust, [8]Adam Yasgar, [9]Crystal McKnight, [10]Matthew B Boxer, ..., [21]Christopher A LeClair, [22]Ganesha Rai, [23]Ajit Jadhav, [24]Brian D Peyser, [25]Christopher P Austin, ... [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.1311846111
PubMed: 24469833 | diffuse large B-cell lymphoma [curation]; B-cell lymphoma [curation]; ibrutinib [curation]; drug screening [curation] | 2014-01-27 |
| A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2 | [1]J Brian Jameson, [2]Auric Kantz, [3]Lena Schultz, [4]Chakrapani Kalyanaraman, [5]Matthew P Jacobson, [6]David J Maloney, [7]Ajit Jadhav, [8]Anton Simeonov, [9]Theodore R Holman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0104094
PubMed: 25111178 | high-throughput screening [curation] | 2014-01-01 |
| Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy | [1]Eric K Hoobler, [2]Ganesha Rai, [3]Andrew Warrilow, [4]Steven C Perry, [5]Christopher J Smyrniotis, [6]Ajit Jadhav, [7]Anton Simeonov, [8]Josie E. Parker, [9]Diane E Kelly, [10]David J Maloney, [11]S L Kelly, [12]Theodore R Holman [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0065928
PubMed: 23826084 | | 2013-06-24 |
| High-throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probe | [1]Megan M McCallum, [2]Premchendar Nandhikonda, [3]Jonathan J Temmer, [4]Charles Eyermann, [5]Anton Simeonov, [6]Ajit Jadhav, [7]Adam Yasgar, [8]David G. Maloney, [9]Leggy A Arnold [Full author list] | Journal of Biomolecular Screening [curation] | DOI: 10.1177/1087057113476090
PubMed: 23446699 | | 2013-02-27 |
| High-throughput 1,536-well fluorescence polarization assays for α(1)-acid glycoprotein and human serum albumin binding | [1]Adam Yasgar, [2]Silviya D Furdas, [3]David J Maloney, [4]Ajit Jadhav, [5]Manfred Jung, [6]Anton Simeonov [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0045594
PubMed: 23029124 | | 2012-01-01 |
| A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ | [1]Kinrin Yamanaka, [2]Dorjbal Dorjsuren, [3]Robert L Eoff, [4]Martin Egli, [5]David J Maloney, [6]Ajit Jadhav, [7]Anton Simeonov, [8]R Stephen Lloyd [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0045032
PubMed: 23056190 | | 2012-01-01 |
| Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection | [1]Dorjbal Dorjsuren, [2]Daemyung Kim, [3]Vaddadi N Vyjayanti, [4]David J Maloney, [5]Ajit Jadhav, [6]David M Wilson, [7]Anton Simeonov [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0047974
PubMed: 23110144 | | 2012-01-01 |
| Exploratory analysis of kinetic solubility measurements of a small molecule library | [1]Rajarshi Guha, [2]Thomas S Dexheimer, [3]Aimee N Kestranek, [4]Ajit Jadhav, [5]Andrew M Chervenak, [6]Michael G Ford, [7]Anton Simeonov, [8]Gregory P Roth, [9]Craig J. Thomas [Full author list] | Bioorganic & Medicinal Chemistry [curation] | DOI: 10.1016/J.BMC.2011.05.005
PubMed: 21640593 | | 2011-05-13 |
| Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay | [1]Stefanie Prast-Nielsen, [2]Thomas S Dexheimer, [3]Lena Schultz, [4]William C Stafford, [5]Qing Cheng, [6]Jianqiang Xu, [7]Ajit Jadhav, [8]Elias S J Arnér, [9]Anton Simeonov [Full author list] | Free Radical Biology and Medicine [curation] | DOI: 10.1016/J.FREERADBIOMED.2011.01.020
PubMed: 21262347 | | 2011-01-22 |
| Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors | [1]Oliver King, [2]Xuan Shirley Li, [3]Masaaki Sakurai, [4]Akane Kawamura, [5]Nathan R Rose, [6]Stanley S Ng, [7]Amy M Quinn, [8]Ganesha Rai, [9]Bryan T Mott, [10]Paul Beswick, [11]Robert J Klose, [12]Udo Oppermann, [13]Ajit Jadhav, [14]Tom D Heightman, [15]David J Maloney, [16]Christopher J. Schofield, [17]Anton Simeonov [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0015535
PubMed: 21124847 | high-throughput screening [curation] | 2010-11-23 |
| A grid algorithm for high throughput fitting of dose-response curve data | [1]Yuhong Wang, [2]Ajit Jadhav, [3]Noel Southal, [4]Ruili Huang, [5]Dac-Trung Nguyen [Full author list] | Current Chemical Genomics [curation] | DOI: 10.2174/1875397301004010057
PubMed: 21331310 | | 2010-10-21 |
| Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. | [1]Ganesha Rai, [2]Victor Kenyon, [3]Ajit Jadhav, [4]Lena Schultz, [5]Michelle Armstrong, [6]J Brian Jameson, [7]Eric Hoobler, [8]William Leister, [9]Anton Simeonov, [10]Theodore R Holman, [11]David J Maloney [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM1008852
PubMed: 20866075 | | 2010-10-01 |
| Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors | [1]Rafaela S Ferreira, [2]Anton Simeonov, [3]Ajit Jadhav, [4]Oliv Eidam, [5]Bryan T Mott, [6]Michael J Keiser, [7]James H McKerrow, [8]David J Maloney, [9]John J Irwin, [10]Brian K. Shoichet [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM100488W
PubMed: 20540517 | high-throughput screening [curation]; drug discovery [curation] | 2010-07-08 |
| Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatB | [1]Bryan T Mott, [2]Rafaela S Ferreira, [3]Anton Simeonov, [4]Ajit Jadhav, [5]Kenny Kean-Hooi Ang, [6]William Leister, [7]Min Shen, [8]Julia T Silveira, [9]Patricia S Doyle, [10]Michelle R Arkin, [11]James H McKerrow, [12]James Inglese, [13]Christopher P Austin, [14]Craig J. Thomas, [15]Brian K. Shoichet, [16]David J Maloney [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM901069A
PubMed: 19908842 | drug discovery [curation] | 2010-01-14 |
| High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships | [1]Frank H Niesen, [2]Lena Schultz, [3]Ajit Jadhav, [4]Chitra Bhatia, [5]Kunde Guo, [6]David J Maloney, [7]Ewa S Pilka, [8]Minghua Wang, [9]Udo Oppermann, [10]Tom D Heightman, [11]Anton Simeonov [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0013719
PubMed: 21072165 | NAD+ binding [curation]; 15-hydroxyprostaglandin dehydrogenase [curation] | 2010-01-01 |
| Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease | [1]Ajit Jadhav, [2]Rafaela S Ferreira, [3]Carleen Klumpp-Thomas, [4]Bryan T Mott, [5]Christopher P Austin, [6]James Inglese, [7]Craig J. Thomas, [8]David J Maloney, [9]Brian K. Shoichet, [10]Anton Simeonov [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM901070C
PubMed: 19908840 | | 2010-01-01 |
| Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a | [1]Feng Liu, [2]Xin Chen, [3]Abdellah Allali-Hassani, [4]Amy M Quinn, [5]Gregory A Wasney, [6]Aiping Dong, [7]Dalia Barsyte, [8]Ivona Kozieradzki, [9]Guillermo Senisterra, [10]Irene Chau, [11]Alena Siarheyeva, [12]Dmitri B Kireev, [13]Ajit Jadhav, [14]J Martin Herold, [15]Stephen V Frye, [16]Cheryl Arrowsmith, [17]Peter J. Brown, [18]Anton Simeonov, [19]Masoud Vedadi, [20]Jian Jin [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM901543M
PubMed: 19891491 | drug discovery [curation] | 2009-12-24 |
| A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase | [1]Adam Yasgar, [2]Timothy L Foley, [3]Ajit Jadhav, [4]James Inglese, [5]Michael D Burkart, [6]Anton Simeonov [Full author list] | Molecular BioSystems [curation] | DOI: 10.1039/B913291K
PubMed: 20094656 | Bacillus subtilis [curation] | 2009-10-13 |
| A miniaturized screen for inhibitors of Jumonji histone demethylases | [1]Masaaki Sakurai, [2]Nathan R Rose, [3]Lena Schultz, [4]Amy M Quinn, [5]Ajit Jadhav, [6]Stanley S Ng, [7]Udo Oppermann, [8]Christopher J. Schofield, [9]Anton Simeonov [Full author list] | Molecular BioSystems [curation] | DOI: 10.1039/B912993F
PubMed: 20094655 | | 2009-10-08 |
| A high-throughput approach for identification of novel general anesthetics | [1]Wendy A Lea, [2]Jin Xi, [3]Ajit Jadhav, [4]Louis Lu, [5]Christopher P Austin, [6]Anton Simeonov, [7]Roderic Eckenhoff [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0007150
PubMed: 19777064 | | 2009-09-24 |
| A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries | [1]Ronald L Johnson, [2]Ruili Huang, [3]Ajit Jadhav, [4]Noel Southall, [5]Jennifer Wichterman, [6]Ryan MacArthur, [7]Menghang Xia, [8]Kun Bi, [9]John Printen, [10]Christopher P Austin, [11]James Inglese [Full author list] | Molecular BioSystems [curation] | DOI: 10.1039/B902021G
PubMed: 19668870 | | 2009-06-19 |
| Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1 | [1]Anton Simeonov, [2]Avanti Kulkarni, [3]Dorjbal Dorjsuren, [4]Ajit Jadhav, [5]Min Shen, [6]Daniel R McNeill, [7]Christopher P Austin, [8]David M Wilson [Full author list] | PLOS One [curation] | DOI: 10.1371/JOURNAL.PONE.0005740
PubMed: 19484131 | | 2009-06-01 |
| Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay | [1]Christophe Marchand, [2]Wendy A Lea, [3]Ajit Jadhav, [4]Thomas S Dexheimer, [5]Christopher P Austin, [6]James Inglese, [7]Yves Pommier, [8]Anton Simeonov [Full author list] | Molecular Cancer Therapeutics [curation] | DOI: 10.1158/1535-7163.MCT-08-0878
PubMed: 19139134 | | 2009-01-01 |
| The pilot phase of the NIH Chemical Genomics Center | [1]Craig J. Thomas, [2]Douglas S Auld, [3]Ruili Huang, [4]Wenwei Huang, [5]Ajit Jadhav, [6]Ronald L Johnson, [7]William Leister, [8]David J Maloney, [9]Juan Jose Marugan, [10]Sam Michael, [11]Anton Simeonov, [12]Noel Southall, [13]Menghang Xia, [14]Wei Zheng, [15]James Inglese, [16]Christopher P Austin [Full author list] | Current Topics in Medicinal Chemistry [curation] | DOI: 10.2174/156802609789753644
PubMed: 19807664 | genomics [curation] | 2009-01-01 |
| Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening | [1]Daniel J Urban, [2]Wei Zheng, [3]Ozlem Goker-Alpan, [4]Ajit Jadhav, [5]Mary E Lamarca, [6]James Inglese, [7]Ellen Sidransky, [8]Christopher P Austin [Full author list] | Combinatorial Chemistry & High Throughput Screening [curation] | DOI: 10.2174/138620708786734244
PubMed: 19075603 | | 2008-12-01 |
| A robotic platform for quantitative high-throughput screening | [1]Sam Michael, [2]Douglas S Auld, [3]Carleen Klumpp-Thomas, [4]Ajit Jadhav, [5]Wei Zheng, [6]Natasha Thorne, [7]Christopher P Austin, [8]James Inglese, [9]Anton Simeonov [Full author list] | Assay and Drug Development Technologies [curation] | DOI: 10.1089/ADT.2008.150
PubMed: 19035846 | robotics [curation]; biomedical investigative technique [curation] | 2008-10-01 |
| A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction | [1]Adam J Kimple, [2]Adam Yasgar, [3]Mark Hughes, [4]Ajit Jadhav, [5]Francis S Willard, [6]Robin E Muller, [7]Christopher P Austin, [8]James Inglese, [9]Gordon C Ibeanu, [10]David Siderovski, [11]Anton Simeonov, [12]Adam Kimple [Full author list] | Combinatorial Chemistry & High Throughput Screening [curation] | DOI: 10.2174/138620708784534770
PubMed: 18537560 | | 2008-06-01 |
| Comprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-Lactamase | [1]Kerim Babaoglu, [2]Anton Simeonov, [3]John J Irwin, [4]Michael E Nelson, [5]Brian Feng, [6]Craig J. Thomas, [7]Laura Cancian, [8]M Paola Costi, [9]David A Maltby, [10]Ajit Jadhav, [11]James Inglese, [12]Christopher P Austin, [13]Brian K. Shoichet [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM701500E
PubMed: 18333608 | drug discovery [curation] | 2008-04-24 |
| Compound Management for Quantitative High-Throughput Screening | [1]Adam Yasgar, [2]Andrew Paul Shinn, [3]Ajit Jadhav, [4]Douglas S Auld, [5]Sam Michael, [6]Wei Zheng, [7]Christopher P Austin, [8]James Inglese, [9]Anton Simeonov [Full author list] | Journal of the Association for Laboratory Automation [curation] | DOI: 10.1016/J.JALA.2007.12.004
PubMed: 18496600 | high-throughput screening [curation] | 2008-04-01 |
| Fluorescence spectroscopic profiling of compound libraries | [1]Anton Simeonov, [2]Ajit Jadhav, [3]Craig J. Thomas, [4]Yuhong Wang, [5]Ruili Huang, [6]Noel Southall, [7]Andrew Paul Shinn, [8]Jeremy Smith, [9]Christopher P Austin, [10]Douglas S Auld, [11]James Inglese [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM701301M
PubMed: 18363325 | | 2008-03-26 |
| Characterization of chemical libraries for luciferase inhibitory activity | [1]Douglas S Auld, [2]Noel Southall, [3]Ajit Jadhav, [4]Ronald L Johnson, [5]David J Diller, [6]Anton Simeonov, [7]Christopher P Austin, [8]James Inglese [Full author list] | Journal of Medicinal Chemistry [curation] | DOI: 10.1021/JM701302V
PubMed: 18363348 | | 2008-03-26 |
| Compound cytotoxicity profiling using quantitative high-throughput screening | [1]Menghang Xia, [2]Ruili Huang, [3]Kristine L Witt, [4]Noel Southall, [5]Jennifer Fostel, [6]Ming-Hsuang Cho, [7]Ajit Jadhav, [8]Cynthia S Smith, [9]James Inglese, [10]Christopher Portier, [11]Raymond R Tice, [12]Christopher P Austin [Full author list] | Environmental Health Perspectives [curation] | DOI: 10.1289/EHP.10727
PubMed: 18335092 | cytotoxicity [curation]; high-throughput screening [curation] | 2008-03-01 |
| Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade | [1]Anton Simeonov, [2]Ajit Jadhav, [3]Ahmed A Sayed, [4]Yuhong Wang, [5]Michael E Nelson, [6]Craig J. Thomas, [7]James Inglese, [8]David L Williams, [9]Christopher P Austin [Full author list] | PLoS Neglected Tropical Diseases [curation] | DOI: 10.1371/JOURNAL.PNTD.0000127
PubMed: 18235848 | high-throughput screening [curation]; Schistosoma mansoni [curation]; infectious disease [curation] | 2008-01-02 |
| A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression | [1]Ronald L Johnson, [2]Wenwei Huang, [3]Ajit Jadhav, [4]Christopher P Austin, [5]James Inglese, [6]Elisabeth D Martinez [Full author list] | Analytical Biochemistry [curation] | DOI: 10.1016/J.AB.2007.12.028
PubMed: 18211814 | high-throughput screening [curation] | 2007-12-25 |
| Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction | [1]Anton Simeonov, [2]Adam Yasgar, [3]Ajit Jadhav, [4]G L Lokesh, [5]Carleen Klumpp, [6]Sam Michael, [7]Christopher P Austin, [8]Amarnath Natarajan, [9]James Inglese [Full author list] | Analytical Biochemistry [curation] | DOI: 10.1016/J.AB.2007.11.039
PubMed: 18158907 | high-throughput screening [curation] | 2007-12-05 |
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease | [1]Wei Zheng, [2]Janak Padia, [3]Daniel J Urban, [4]Ajit Jadhav, [5]Ozlem Goker-Alpan, [6]Anton Simeonov, [7]Ehud Goldin, [8]Douglas S Auld, [9]Mary E LaMarca, [10]James Inglese, [11]Christopher P Austin, [12]Ellen Sidransky [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.0705637104
PubMed: 17670938 | molecular chaperones [curation]; high-throughput screening [curation]; Gaucher's disease [curation] | 2007-08-01 |
| Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries | [1]James Inglese, [2]Douglas S Auld, [3]Ajit Jadhav, [4]Ronald L Johnson, [5]Anton Simeonov, [6]Adam Yasgar, [7]Wei Zheng, [8]Christopher P Austin [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [curation] | DOI: 10.1073/PNAS.0604348103
PubMed: 16864780 | high-throughput screening [curation] | 2006-07-24 |
| Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format | [1]Douglas S Auld, [2]Ronald L Johnson, [3]Ya-qin Zhang, [4]Henrike Veith, [5]Ajit Jadhav, [6]Adam Yasgar, [7]Anton Simeonov, [8]Wei Zheng, [9]Elisabeth D Martinez, [10]John K Westwick, [11]Christopher P Austin, [12]James Inglese [Full author list] | Methods in Enzymology [curation] | DOI: 10.1016/S0076-6879(06)14029-X
PubMed: 17110211 | | 2006-01-01 |
| Streamlined system for purifying and quantifying a diverse library of compounds and the effect of compound concentration measurements on the accurate interpretation of biological assay results | [1]Ioana G Popa-Burke, [2]Olga Issakova, [3]James D Arroway, [4]Paul Bernasconi, [5]Min Chen, [6]Louis Coudurier, [7]Scott Galasinski, [8]Ajit Jadhav, [9]William P Janzen, [10]Dennis Lagasca, [11]Darren Liu, [12]Roderic S Lewis, [13]Robert P Mohney, [14]Nikolai Sepetov, [15]Darren A Sparkman, [16]C Nicholas Hodge [Full author list] | Analytical Chemistry [curation] | DOI: 10.1021/AC0491859
PubMed: 15595870 | | 2004-12-01 |