| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date |
|---|
| Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner | [1]Khaled S Abd-Elrahman, [2]Awatif Albaker, [3]Jessica M de Souza, [4]Fabiola M Ribeiro, [5]Michael G Schlossmacher, [6]Mario Tiberi, [7]Alison Hamilton, [8]Stephen S G Ferguson [Full author list] | Science Signaling [curation] | DOI: 10.1126/SCISIGNAL.ABD2494
PubMed: 33323410 | | 2020-12-15 |
| mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease | [1]Jéssica M de Souza, [2]Khaled S Abd-Elrahman, [3]Fabiola M Ribeiro, [4]Stephen S G Ferguson [Full author list] | Molecular Brain [curation] | DOI: 10.1186/S13041-020-00657-7
PubMed: 32859226 | Huntington's disease [curation] | 2020-08-28 |
| mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson's Disease | [1]Kyle Farmer, [2]Khaled S Abd-Elrahman, [3]Alexa Derksen, [4]Elyn M Rowe, [5]Ashley M Thompson, [6]Christopher A Rudyk, [7]Natalie A Prowse, [8]Zachary Dwyer, [9]Samantha C Bureau, [10]Teresa Fortin, [11]Stephen S G Ferguson, [12]Shawn Hayley [Full author list] | Molecular Neurobiology [curation] | DOI: 10.1007/S12035-019-01818-Z
PubMed: 31754998 | Parkinson's disease [curation] | 2019-11-21 |
| Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington's pathology in zQ175 mice | [1]Khaled S Abd-Elrahman, [2]Stephen S G Ferguson [Full author list] | Molecular Brain [curation] | DOI: 10.1186/S13041-019-0456-1
PubMed: 30961637 | Huntington's disease [curation]; autophagy [curation]; CTEP [curation] | 2019-04-08 |
| Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation | [1]Lorena Bianchine Areal, [2]Alison Hamilton, [3]Cristina Martins-Silva, [4]Rita Gomes Wanderley Pires, [5]Stephen S G Ferguson [Full author list] | Molecular Brain [curation] | DOI: 10.1186/S13041-019-0434-7
PubMed: 30803445 | | 2019-02-25 |
| Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer's disease mouse models | [1]Khaled S Abd-Elrahman, [2]Alison Hamilton, [3]Maryam Vasefi, [4]Stephen S G Ferguson [Full author list] | Molecular Brain [curation] | DOI: 10.1186/S13041-018-0364-9
PubMed: 29631635 | Alzheimer's disease [curation]; autophagy [curation] | 2018-04-10 |
| mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington's disease | [1]Khaled S Abd-Elrahman, [2]Alison Hamilton, [3]Shaunessy R Hutchinson, [4]Fang Liu, [5]Ryan C Russell, [6]Stephen S G Ferguson [Full author list] | Science Signaling [curation] | DOI: 10.1126/SCISIGNAL.AAN6387
PubMed: 29259100 | Huntington's disease [curation]; autophagy [curation] | 2017-12-19 |