Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
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The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells | [1]Emma Rörby, [2]Matilda Billing, [3]Maria Dahl, [4]Sarah Warsi, [5]Silja Andradottir, [6]Kenichi Miharada, [7]Kavitha Siva, [8]Jan-Ingvar Jönsson, [9]Ulrika Blank, [10]Göran Karlsson, [11]Stefan Karlsson [Full author list] | Scientific Reports [missing] | DOI: 10.1038/S41598-017-09452-2 [ORCID] PubMed: 28860613 [ORCID]
| | 2017-08-31 | |
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia | [1]Shubhranshu Debnath, [2]Pekka Jaako, [3]Kavitha Siva, [4]Michael Rothe, [5]Jun Chen, [6]Maria Dahl, [7]H Bobby Gaspar, [8]Johan Flygare, [9]Axel Schambach, [10]Stefan Karlsson [Full author list] | Molecular Therapy [missing] | DOI: 10.1016/J.YMTHE.2017.04.002 [ORCID] PubMed: 28434866 [ORCID]
| | 2017-04-20 | |
A network including TGFβ/Smad4, Gata2, and p57 regulates proliferation of mouse hematopoietic progenitor cells | [1]Matilda Billing, [2]Emma Rörby, [3]Gillian May, [4]Alex J Tipping, [5]Shamit Soneji, [6]John Brown, [7]Marjo Salminen, [8]Göran Karlsson, [9]Tariq Enver, [10]Stefan Karlsson [Full author list] | Experimental Hematology [missing] | DOI: 10.1016/J.EXPHEM.2016.02.001 [ORCID] PubMed: 26876150 [ORCID]
| | 2016-02-10 | |
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases | [1]André R A Marques, [2]Mina Mirzaian, [3]Hisako Akiyama, [4]Patrick Wisse, [5]Maria João Ferraz, [6]Paulo Gaspar, [7]Karen Ghauharali-van der Vlugt, [8]Rianne Meijer, [9]Pilar Giraldo, [10]Pilar Alfonso, [11]Pilar Irún, [12]Maria Dahl, [13]Stefan Karlsson, [14]Elena Pavlova, [15]Timothy M Cox, ... [Full author list] | Journal of Lipid Research [missing] | DOI: 10.1194/JLR.M064923 [ORCID] PubMed: 26724485 [ORCID]
| Glucosylceramidase beta [missing]; glucosylceramide catabolic process [missing]; Glucosylceramidase beta 3 (gene/pseudogene) [missing]; Glucosidase beta 2 [missing] | 2016-01-02 | |
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia | [1]Sara E Sjögren, [2]Kavitha Siva, [3]Shamit Soneji, [4]Amee George, [5]Marcus Winkler, [6]Pekka Jaako, [7]Marcin W Wlodarski, [8]Stefan Karlsson, [9]Ross D. Hannan, [10]Johan Flygare [Full author list] | British Journal of Haematology [missing] | DOI: 10.1111/BJH.13632 [ORCID] PubMed: 26305041 [ORCID]
| | 2015-08-25 | |
Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice | [1]Maria Dahl, [2]Alexander Doyle, [3]Karin Olsson, [4]Jan-Eric Månsson, [5]André R A Marques, [6]Mina Mirzaian, [7]Johannes M Aerts, [8]Mats Ehinger, [9]Michael Rothe, [10]Ute Modlich, [11]Axel Schambach, [12]Stefan Karlsson [Full author list] | Molecular Therapy [missing] | DOI: 10.1038/MT.2015.16 [ORCID] PubMed: 25655314 [ORCID]
| gene therapy [missing] | 2015-02-06 | |
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease | [1]Sofie Singbrant, [2]Meaghan Wall, [3]Jennifer Moody, [4]Göran Karlsson, [5]Alistair M Chalk, [6]Brian Liddicoat, [7]Megan R Russell, [8]Carl R Walkley, [9]Stefan Karlsson [Full author list] | Haematologica [missing] | DOI: 10.3324/HAEMATOL.2013.093971 [ORCID] PubMed: 24415629 [ORCID]
| | 2014-01-10 | |
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche | [1]Kenichi Miharada, [2]Göran Karlsson, [3]Matilda Rehn, [4]Emma Rörby, [5]Kavitha Siva, [6]Jörg Cammenga, [7]Stefan Karlsson [Full author list] | Annals of the New York Academy of Sciences [missing] | DOI: 10.1111/J.1749-6632.2012.06564.X [ORCID] PubMed: 22901256 [ORCID]
| hypoxia [missing] | 2012-08-01 | Stefan Karlsson (Q96576920; 2 items)
|
Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia | [1]Kenichi Miharada, [2]Stefan Karlsson [Full author list] | Cell Stem Cell [missing] | DOI: 10.1016/J.STEM.2012.01.008 [ORCID] PubMed: 22305558 [ORCID]
| leukemia [missing] | 2012-02-01 | |
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia | [1]Pekka Jaako, [2]Johan Flygare, [3]Karin Olsson, [4]Ronan Quere, [5]Mats Ehinger, [6]Adrianna Henson, [7]Steven Ellis, [8]Axel Schambach, [9]Christopher Baum, [10]Johan Richter, [11]Jonas Larsson, [12]David Bryder, [13]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2011-08-371963 [ORCID] PubMed: 21989989 [ORCID]
| patient [missing]; bone marrow [missing] | 2011-10-11 | |
Cripto regulates hematopoietic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78 | [1]Kenichi Miharada, [2]Göran Karlsson, [3]Matilda Rehn, [4]Emma Rörby, [5]Kavitha Siva, [6]Jörg Cammenga, [7]Stefan Karlsson [Full author list] | Cell Stem Cell [missing] | DOI: 10.1016/J.STEM.2011.07.016 [ORCID] PubMed: 21982233 [ORCID]
| hypoxia [missing] | 2011-10-01 | |
Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells | [1]Noriko Miyake, [2]Koichi Miyake, [3]Stefan Karlsson, [4]Takashi Shimada [Full author list] | Molecular Therapy [missing] | DOI: 10.1038/MT.2010.74 [ORCID] PubMed: 20424597 [ORCID]
| metachromatic leukodystrophy [missing]; overexpression [missing] | 2010-04-27 | |
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling | [1]Sofie Singbrant Söderberg, [2]Göran Karlsson, [3]Stefan Karlsson [Full author list] | Annals of the New York Academy of Sciences [missing] | DOI: 10.1111/J.1749-6632.2009.04569.X [ORCID] PubMed: 19796233 [ORCID]
| hemopoiesis [missing] | 2009-09-01 | |
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference | [1]Adrianna Vlachos, [2]Sarah Ball, [3]Niklas Dahl, [4]Blanche P Alter, [5]Sujit Sheth, [6]Ugo Ramenghi, [7]Joerg J Meerpohl, [8]Stefan Karlsson, [9]Johnson M Liu, [10]Thierry Leblanc, [11]Carole Paley, [12]Elizabeth M Kang, [13]Eva Judmann Leder, [14]Eva Atsidaftos, [15]Akiko Shimamura, [16]Monica Bessler, [17]Bertil Glader, [18]Jeffrey M Lipton, [19]Participants of Sixth Annual Daniella Maria Arturi International Consensus Conference [Full author list] | British Journal of Haematology [missing] | DOI: 10.1111/J.1365-2141.2008.07269.X [ORCID] PubMed: 18671700 [ORCID]
| Diamond-Blackfan anemia [missing] | 2008-09-01 | |
Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia | [1]Koich Miyake, [2]Taiju Utsugisawa, [3]Johan Flygare, [4]Thomas Kiefer, [5]Isao Hamaguchi, [6]Johan Richter, [7]Stefan Karlsson [Full author list] | Stem Cells [missing] | DOI: 10.1634/STEMCELLS.2007-0569 [ORCID] PubMed: 17962699 [ORCID]
| apoptotic process [missing] | 2007-10-25 | |
Murine models of acute neuronopathic Gaucher disease | [1]Ida Berglin Enquist, [2]Christophe Lo Bianco, [3]Andreas Ooka, [4]Eva Nilsson, [5]Jan-Eric Månsson, [6]Mats Ehinger, [7]Johan Richter, [8]Roscoe O Brady, [9]Deniz Kirik, [10]Stefan Karlsson [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0708086104 [ORCID] PubMed: 17954912 [ORCID]
| Gaucher's disease [missing]; Glucosidase, beta, acid [missing]; murine model [missing] | 2007-10-22 | |
Signaling pathways governing stem-cell fate | [1]Ulrika Blank, [2]Göran Karlsson, [3]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2007-07-075168 [ORCID] PubMed: 17914027 [ORCID]
| | 2007-10-03 | |
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects | [1]Mattias Magnusson, [2]Ann C. M. Brun, [3]H. Jeffrey Lawrence, [4]Stefan Karlsson [Full author list] | Experimental Hematology [missing] | DOI: 10.1016/J.EXPHEM.2007.05.011 [ORCID] PubMed: 17761289 [ORCID]
| Homeobox B3 [missing]; Homeobox A9 [missing]; Homeobox B4 [missing] | 2007-09-01 | |
Smad4 is critical for self-renewal of hematopoietic stem cells | [1]Göran Karlsson, [2]Ulrika Blank, [3]Jennifer L Moody, [4]Mats Ehinger, [5]Sofie Singbrant, [6]Chu-Xia Deng, [7]Stefan Karlsson [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20060465 [ORCID] PubMed: 17353364 [ORCID]
| | 2007-03-19 | |
Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: applications and prospects | [1]Marcus Järås, [2]Ann C M Brun, [3]Stefan Karlsson, [4]Xiaolong Fan [Full author list] | Experimental Hematology [missing] | DOI: 10.1016/J.EXPHEM.2006.11.004 [ORCID] PubMed: 17309814 [ORCID]
| Adenoviridae [missing] | 2007-03-01 | |
Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits | [1]Johan Flygare, [2]Anna Aspesi, [3]Joshua C Bailey, [4]Koichi Miyake, [5]Jacqueline M Caffrey, [6]Stefan Karlsson, [7]Steven R Ellis [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2006-07-038232 [ORCID] PubMed: 16990592 [ORCID]
| cell biology [missing]; Diamond-Blackfan anemia [missing]; Ribosomal protein S19 [missing]; maturation of SSU-rRNA [missing] | 2007-02-01 | |
Diamond-Blackfan anemia: erythropoiesis lost in translation | [1]Johan Flygare, [2]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2006-09-001222 [ORCID] PubMed: 17164339 [ORCID]
| Diamond-Blackfan anemia [missing] | 2006-12-12 | |
Effective cell and gene therapy in a murine model of Gaucher disease | [1]Ida Berglin Enquist, [2]Eva Nilsson, [3]Andreas Ooka, [4]Jan-Eric Månsson, [5]Karin Olsson, [6]Mats Ehinger, [7]Roscoe O Brady, [8]Johan Richter, [9]Stefan Karlsson [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0606016103 [ORCID] PubMed: 16954197 [ORCID]
| gene therapy [missing]; Gaucher's disease [missing]; murine model [missing] | 2006-09-05 | |
Smad5 is dispensable for adult murine hematopoiesis | [1]Sofie Singbrant, [2]Jennifer L Moody, [3]Ulrika Blank, [4]Göran Karlsson, [5]Lieve Umans, [5-Q42744938]Lieve Umans, [6]An Zwijsen, [6-Q42744796]An Zwijsen, [7]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2006-02-003384 [ORCID] PubMed: 16896158 [ORCID]
| hemopoiesis [missing] | 2006-08-08 | |
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion | [1]Marek Dudas, [2]Jieun Kim, [3]Wai-Yee Li, [4]Andre Nagy, [5]Jonas Larsson, [6]Stefan Karlsson, [7]Yang Chai, [8]Vesa Kaartinen [Full author list] | Developmental Biology [missing] | DOI: 10.1016/J.YDBIO.2006.05.030 [ORCID] PubMed: 16806156 [ORCID]
| cell biology [missing]; morphogenesis [missing]; SMAD family member 2 [missing]; common-partner SMAD protein phosphorylation [missing]; SMAD family member 2 [missing]; Activin receptor IIB [missing]; Transforming growth factor, beta receptor I [missing]; Transforming growth factor, beta receptor II [missing]; Transforming growth factor beta-3 [missing] | 2006-05-27 | |
A road map toward defining the role of Smad signaling in hematopoietic stem cells | [1]Taiju Utsugisawa, [2]Jennifer L Moody, [3]Marie Aspling, [4]Eva Nilsson, [5]Leif Carlsson, [6]Stefan Karlsson [Full author list] | Stem Cells [missing] | DOI: 10.1634/STEMCELLS.2005-0263 [ORCID] PubMed: 16357343 [ORCID]
| | 2005-12-15 | |
The role of Smad signaling in hematopoiesis | [1]Jonas Larsson, [2]Stefan Karlsson [Full author list] | Oncogene [missing] | DOI: 10.1038/SJ.ONC.1208920 [ORCID] PubMed: 16123801 [ORCID]
| hemopoiesis [missing] | 2005-08-01 | |
Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19. | [1]Koichi Miyake, [2]Johan Flygare, [3]Thomas Kiefer, [4]Taiju Utsugisawa, [5]Johan Richter, [6]Zhi Ma, [7]Maciej Wiznerowicz, [8]Didier Trono, [9]Stefan Karlsson [Full author list] | Molecular Therapy [missing] | DOI: 10.1016/J.YMTHE.2004.12.001 [ORCID] PubMed: 15771965 [ORCID]
| Diamond-Blackfan anemia [missing] | 2005-04-01 | |
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia. | [1]Johan Flygare, [2]Thomas Kiefer, [3]Koichi Miyake, [4]Taiju Utsugisawa, [5]Isao Hamaguchi, [6]Lydie Da Costa, [7]Johan Richter, [8]Edward J Davey, [9]Hans Matsson, [10]Niklas Dahl, [11]Maciej Wiznerowicz, [12]Didier Trono, [13]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2004-08-3115 [ORCID] PubMed: 15626736 [ORCID]
| | 2004-12-30 | |
Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells | [1]Ann C. M. Brun, [2]Jon Mar Björnsson, [3]Mattias Magnusson, [4]Nina Larsson, [5]Per Leveén, [6]Mats Ehinger, [7]Eva Nilsson, [8]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2003-10-3557 [ORCID] PubMed: 14962901 [ORCID]
| Homeobox B4 [missing] | 2004-06-01 | |
Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation | [1]Hans Matsson, [2]Edward J Davey, [3]Natalia Draptchinskaia, [4]Isao Hamaguchi, [5]Andreas Ooka, [6]Per Levéen, [7]Erik Forsberg, [8]Stefan Karlsson, [9]Niklas Dahl [Full author list] | Molecular and Cellular Biology [missing] | DOI: 10.1128/MCB.24.9.4032-4037.2004 [ORCID] PubMed: 15082795 [ORCID]
| | 2004-05-01 | |
Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation | [1]Yutaka Sasaki, [2]Christina T Jensen, [3]Stefan Karlsson, [4]Sten Eirik W Jacobsen [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2003-07-2277 [ORCID] PubMed: 15105286 [ORCID]
| | 2004-04-22 | |
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences | [1]Christopher Baum, [2]Christof von Kalle, [3]Frank J T Staal, [4]Zhixiong Li, [5]Boris Fehse, [6]Manfred Schmidt, [7]Floor Weerkamp, [8]Stefan Karlsson, [9]Gerard Wagemaker, [10]David A Williams [Full author list] | Molecular Therapy [missing] | DOI: 10.1016/J.YMTHE.2003.10.013 [ORCID] PubMed: 14741772 [ORCID]
| gene therapy [missing] | 2004-01-01 | |
TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro | [1]Jonas Larsson, [2]Ulrika Blank, [3]Hildur Helgadottir, [4]Jon Mar Björnsson, [5]Mats Ehinger, [6]Marie-José Goumans, [7]Xiaolong Fan, [8]Per Levéen, [9]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD-2003-04-1300 [ORCID] PubMed: 12842983 [ORCID]
| | 2003-07-03 | |
Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4 | [1]Jon Mar Björnsson, [2]Nina Larsson, [3]Ann C M Brun, [4]Mattias Magnusson, [5]Elisabet Andersson, [6]Patrik Lundström, [7]Jonas Larsson, [8]Ewa Repetowska, [9]Mats Ehinger, [10]Richard Humphries, [11]Stefan Karlsson [Full author list] | Molecular and Cellular Biology [missing] | DOI: 10.1128/MCB.23.11.3872-3883.2003 [ORCID] PubMed: 12748289 [ORCID]
| | 2003-06-01 | |
Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer | [1]Isao Hamaguchi, [2]Johan Flygare, [3]Hiroshi Nishiura, [4]Ann C M Brun, [5]Andreas Ooka, [6]Thomas Kiefer, [7]Zhi Ma, [8]Niklas Dahl, [9]Johan Richter, [10]Stefan Karlsson [Full author list] | Molecular Therapy [missing] | DOI: 10.1016/S1525-0016(03)00091-1 [ORCID] PubMed: 12718904 [ORCID]
| Diamond-Blackfan anemia [missing] | 2003-05-01 | |
Gene transfer improves erythroid development in ribosomal protein S19-deficient Diamond-Blackfan anemia | [1]Isao Hamaguchi, [2]Andreas Ooka, [3]Ann Brun, [4]Johan Richter, [5]Niklas Dahl, [6]Stefan Karlsson [Full author list] | Blood [missing] | DOI: 10.1182/BLOOD.V100.8.2724 [ORCID] PubMed: 12351378 [ORCID]
| | 2002-10-01 | |
Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach | [1]Helga Björgvinsdóttir, [2]David Bryder, [3]Ewa Sitnicka, [4]Veslemøy Ramsfjell, [5]Ineke De Jong, [6]Karin Olsson, [7]Corinne Rusterholz, [8]Stefan Karlsson, [9]Sten Eirik W Jacobsen [Full author list] | Human Gene Therapy [missing] | DOI: 10.1089/104303402753812467 [ORCID] PubMed: 12067439 [ORCID]
| | 2002-06-01 | |