| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain | [1]Gabriele Cerutti, [2]Yicheng Guo, [3]Pengfei Wang, [4]Manoj S Nair, [5]Maple Wang, [6]Yaoxing Huang, [7]Jian Yu, [8]Lihong Liu, [9]Phinikoula S Katsamba, [10]Fabiana Bahna, [11]Eswar R Reddem, [12]Peter D Kwong, [13]David D Ho, [14]Zizhang Sheng, [15]Lawrence Shapiro [Full author list] | Cell Reports [missing] | DOI: 10.1016/J.CELREP.2021.109928 [ORCID]
PubMed: 34706271 [ORCID]
| NTD [missing]; neutralizing antibody [missing]; Cryo-EM [missing]; SARS-CoV-2 [missing]; variant of concern [missing] | 2021-11-02 | Yaoxing Huang (Q97650828; 8 items)
|
| Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses | [1]Bailey B Banach, [2]Gabriele Cerutti, [3]Ahmed S Fahad, [4]Chen-Hsiang Shen, [5]Matheus Oliveira De Souza, [6]Phinikoula S Katsamba, [7]Yaroslav Tsybovsky, [8]Pengfei Wang, [9]Manoj S Nair, [10]Yaoxing Huang, [11]Irene M Francino-Urdániz, [12]Paul J Steiner, ... [Full author list] | Cell Reports [missing] | DOI: 10.1016/J.CELREP.2021.109771 [ORCID]
PubMed: 34587480 [ORCID]
| B-cell [missing]; Yeast display [missing]; SARS-CoV-2 [missing] | 2021-10-05 | Yaoxing Huang (Q97650828; 8 items)
|
| Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies | [1]Gabriele Cerutti, [2]Micah Rapp, [3]Yicheng Guo, [4]Fabiana Bahna, [5]Jude Bimela, [6]Eswar R Reddem, [7]Jian Yu, [8]Pengfei Wang, [9]Lihong Liu, [10]Yaoxing Huang, [11]David D Ho, [12]Peter D Kwong, [13]Zizhang Sheng, [14]Lawrence Shapiro [Full author list] | Structure [missing] | DOI: 10.1016/J.STR.2021.05.014 [ORCID]
PubMed: 34111408 [ORCID]
| neutralizing antibody [missing]; Cryo-EM [missing]; SARS-CoV-2 [missing]; SARS-CoV-2 Alpha variant [missing]; SARS-CoV-2 Beta variant [missing]; Lineage B.1.1.7 with E484K [missing] | 2021-07-01 | Yaoxing Huang (Q97650828; 8 items)
|
| Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class | [1]Micah Rapp, [2]Yicheng Guo, [3]Eswar R Reddem, [4]Jian Yu, [5]Lihong Liu, [6]Pengfei Wang, [7]Gabriele Cerutti, [8]Phinikoula Katsamba, [9]Jude S Bimela, [10]Fabiana A Bahna, [11]Seetha M Mannepalli, [12]Baoshan Zhang, [13]Peter D Kwong, [14]Yaoxing Huang, [15]David D Ho, [16]Lawrence Shapiro, [17]Zizhang Sheng [Full author list] | Cell Reports [missing] | DOI: 10.1016/J.CELREP.2021.108950 [ORCID]
PubMed: 33794145 [ORCID]
| neutralizing antibody [missing]; SARS-CoV-2 [missing] | 2021-04-06 | Yaoxing Huang (Q97650828; 8 items)
|
| The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8 | [1]Miklos Guttman, [2]Neal N Padte, [3]Yaoxing Huang, [4]Jian Yu, [5]Gabriel J Rocklin, [6]Brian D Weitzner, [7]Michele Scian, [8]David D Ho, [9]Kelly K Lee [Full author list] | Scientific Reports [missing] | DOI: 10.1038/S41598-020-71184-7 [ORCID]
PubMed: 32868832 [ORCID]
| | 2020-08-31 | |
| In Vivo Expressed Biologics for Infectious Disease Prophylaxis: Rapid Delivery of DNA-Based Antiviral Antibodies | [1]Chasity D Andrews, [2]Yaoxing Huang, [3]David D Ho, [4]Rachel A Liberatore [Full author list] | Emerging Microbes & Infections [missing] | DOI: 10.1080/22221751.2020.1787108 [ORCID]
PubMed: 32579067 [ORCID]
| infectious disease [missing] | 2020-06-24 | |
| Engineering multi-specific antibodies against HIV-1 | [1]Neal N Padte, [2]Jian Yu, [3]Yaoxing Huang, [4]David D Ho [Full author list] | Retrovirology [missing] | DOI: 10.1186/S12977-018-0439-9 [ORCID]
PubMed: 30157871 [ORCID]
| virus [missing]; virology [missing]; globulins [missing]; blood proteins [missing]; neutralizing antibody [missing]; infectious disease [missing]; human immunodeficiency virus infectious disease [missing]; RNA virus infectious disease [missing]; Retroviridae infectious disease [missing]; biomedical investigative technique [missing] | 2018-08-29 | |
| DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers | [1]Madhura Mukhopadhyay, [2]Moran Galperin, [3]Mandar Patgaonkar, [4]Sandhya Vasan, [5]David D Ho, [6]Alexandre Nouël, [7]Mathieu Claireaux, [8]Daniela Benati, [9]Olivier Lambotte, [10]Yaoxing Huang, [11]Lisa A Chakrabarti [Full author list] | Journal of Immunology [missing] | DOI: 10.4049/JIMMUNOL.1700953 [ORCID]
PubMed: 28993513 [ORCID]
| electroporation [missing] | 2017-10-09 | |
| In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections | [1]Chasity D Andrews, [2]Yang Luo, [3]Ming Sun, [4]Jian Yu, [5]Arthur J Goff, [6]Pamela J Glass, [7]Neal N Padte, [8]Yaoxing Huang, [9]David D Ho [Full author list] | Molecular Therapy. Methods & Clinical Development [missing] | DOI: 10.1016/J.OMTM.2017.09.003 [ORCID]
PubMed: 29034261 [ORCID]
| electroporation [missing]; Orthoebolavirus zairense [missing] | 2017-09-20 | Yaoxing Huang (Q97650828; 8 items)
|
| Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity | [1]Yaoxing Huang, [2]Jian Yu, [3]Anastasia Lanzi, [4]Xin Yao, [5]Chasity D Andrews, [6]Lily Tsai, [7]Mili R Gajjar, [8]Ming Sun, [9]Michael S Seaman, [10]Neal N Padte, [11]David D Ho [Full author list] | Cell [missing] | DOI: 10.1016/J.CELL.2016.05.024 [ORCID]
PubMed: 27315479 [ORCID]
| antibody [missing] | 2016-06-01 | |
| Rational design and characterization of the novel, broad and potent bispecific HIV-1 neutralizing antibody iMabm36. | [1]Ming Sun, [2]Craig S Pace, [3]Xin Yao, [4]Faye Yu, [5]Neal N Padte, [6]Yaoxing Huang, [7]Michael S Seaman, [8]Qihan Li, [9]David D Ho [Full author list] | Journal of Acquired Immune Deficiency Syndromes [missing] | DOI: 10.1097/QAI.0000000000000218 [ORCID]
PubMed: 24853313 [ORCID]
| antibody [missing] | 2014-08-01 | |
| Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse mo | [1]Chandrabali Ghose, [2]Janneke M Verhagen, [3]Xinhua Chen, [4]Jian Yu, [5]Yaoxing Huang, [6]Olivia Chenesseau, [7]Ciarán P Kelly, [8]David D Ho [Full author list] | Infection and Immunity [missing] | DOI: 10.1128/IAI.01074-12 [ORCID]
PubMed: 23545305 [ORCID]
| Clostridium difficile [missing]; toll-like receptor [missing]; Salmonella enterica [missing] | 2013-04-01 | |
| HIV-1 and influenza antigens synthetically linked to IgG2a Fc elicit superior humoral responses compared to unmodified antigens in mice | [1]Gerasimos J Zaharatos, [2]Jian Yu, [3]Craig Pace, [4]Yang Song, [5]Sandhya Vasan, [6]David D Ho, [7]Yaoxing Huang [Full author list] | Vaccine [missing] | DOI: 10.1016/J.VACCINE.2011.10.056 [ORCID]
PubMed: 22064264 [ORCID]
| | 2011-11-04 | |
| Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A. | [1]Juliana Idoyaga, [2]Ashira Lubkin, [3]Christopher Fiorese, [4]Mireille H. Lahoud, [5]Irina Caminschi, [6]Yaoxing Huang, [7]Anthony Rodriguez, [8]Björn E Clausen, [9]Chae Gyu Park, [10]Christine Trumpfheller, [11]Ralph Steinman [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1019547108 [ORCID]
PubMed: 21262813 [ORCID]
| antibody [missing]; dendritic cell [missing] | 2011-01-24 | |
| In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers | [1]Sandhya Vasan, [2]Arlene Hurley, [3]Sarah J Schlesinger, [4]Drew Hannaman, [5]David F Gardiner, [6]Daniel P Dugin, [7]Mar Boente-Carrera, [8]Roselle Vittorino, [9]Marina Caskey, [10]Johanne Andersen, [11]Yaoxing Huang, [12]Josephine H Cox, [13]Tony Tarragona-Fiol, ... [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0019252 [ORCID]
PubMed: 21603651 [ORCID]
| vaccine [missing]; electroporation [missing] | 2011-01-01 | |
| Epitope mapping of ibalizumab, a humanized anti-CD4 monoclonal antibody with anti-HIV-1 activity in infected patients | [1]Ruijiang Song, [2]David Franco, [3]Chia-Ying Kao, [4]Faye Yu, [5]Yaoxing Huang, [6]David D Ho [Full author list] | Journal of Virology [missing] | DOI: 10.1128/JVI.00453-10 [ORCID]
PubMed: 20463063 [ORCID]
| antibody [missing] | 2010-05-12 | |
| Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine | [1]Sandhya Vasan, [2]Sarah J Schlesinger, [3]Zhiwei Chen, [4]Arlene Hurley, [5]Angela Lombardo, [6]Soe Than, [7]Phumla Adesanya, [8]Catherine Bunce, [9]Mark Boaz, [10]Rosanne Boyle, ..., [16]Qing Fang, [17]LeiBa, [18]Yaoxing Huang, [19]Gerasimos J Zaharatos, [20]David F Gardiner, ... [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0008816 [ORCID]
PubMed: 20111599 [ORCID]
| | 2010-01-25 | |
| Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine | [1]Sandhya Vasan, [2]Sarah J Schlesinger, [3]Yaoxing Huang, [4]Arlene Hurley, [5]Angela Lombardo, [6]Zhiwei Chen, [7]Soe Than, [8]Phumla Adesanya, [9]Catherine Bunce, [10]Mark Boaz, ... [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0008617 [ORCID]
PubMed: 20111582 [ORCID]
| | 2010-01-25 | |
| HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC | [1]Leonia Bozzacco, [2]Christine Trumpfheller, [3]Yaoxing Huang, [4]Maria Paula Longhi, [5]Irina Shimeliovich, [6]Joseph D Schauer, [7]Chae Gyu Park, [8]Ralph Steinman [Full author list] | European Journal of Immunology [missing] | DOI: 10.1002/EJI.200939748 [ORCID]
PubMed: 19830741 [ORCID]
| antibody [missing] | 2010-01-01 | |
| A recoding method to improve the humoral immune response to an HIV DNA vaccine | [1]Yaoxing Huang, [2]Michael Krasnitz, [3]Raúl Rabadán, [4]Daniela Witten, [5]Yang Song, [6]Arnold J Levine, [7]David D Ho, [8]Harlan Robins [Full author list] | PLOS One [missing] | DOI: 10.1371/JOURNAL.PONE.0003214 [ORCID]
PubMed: 18791646 [ORCID]
| | 2008-09-15 | |
| The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells | [1]Godwin Nchinda, [2]Janelle Kuroiwa, [3]Margarita Oks, [4]Christine Trumpfheller, [5]Chae Gyu Park, [6]Yaoxing Huang, [7]Drew Hannaman, [8]Sarah J Schlesinger, [9]Olga Mizenina, [10]Michel C. Nussenzweig, [11]Klaus Überla, [12]Ralph Steinman [Full author list] | Journal of Clinical Investigation [missing] | DOI: 10.1172/JCI34224 [ORCID]
PubMed: 18324335 [ORCID]
| dendritic cell [missing] | 2008-04-01 | Yaoxing Huang (Q97650828; 8 items)
|
| Design, construction, and characterization of a dual-promoter multigenic DNA vaccine directed against an HIV-1 subtype C/B' recombinant. | [1]Yaoxing Huang, [2]Zhiwei Chen, [3]Wenyong Zhang, [4]Deborah Gurner, [5]Yang Song, [6]David F Gardiner, [7]David D Ho [Full author list] | Journal of Acquired Immune Deficiency Syndromes [missing] | DOI: 10.1097/QAI.0B013E3181651B9D [ORCID]
PubMed: 18209683 [ORCID]
| vaccine engineering [missing]; DNA design [missing] | 2008-04-01 | |
| Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, alpha-galactosylceramide | [1]Yaoxing Huang, [2]Alex Chen, [3]Xiangming Li, [4]Zhiwei Chen, [5]Wenyong Zhang, [6]Yang Song, [7]Deborah Gurner, [8]David Gardiner, [9]Sankha Basu, [10]David D Ho, [11]Moriya Tsuji [Full author list] | Vaccine [missing] | DOI: 10.1016/J.VACCINE.2008.02.002 [ORCID]
PubMed: 18329757 [ORCID]
| vaccine [missing] | 2008-02-20 | Yaoxing Huang (Q97650828; 8 items)
|
| The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine | [1]Christine Trumpfheller, [2]Marina Caskey, [3]Godwin Nchinda, [4]Maria Paula Longhi, [5]Olga Mizenina, [6]Yaoxing Huang, [7]Sarah J Schlesinger, [8]Marco Colonna, [9]Ralph Steinman [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.0711976105 [ORCID]
PubMed: 18256187 [ORCID]
| vaccine [missing]; dendritic cell [missing] | 2008-02-06 | |
| Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine | [1]Christine Trumpfheller, [2]Jennifer S Finke, [3]Carolina B López, [4]Thomas M Moran, [5]Bruno Moltedo, [6]Helena Soares, [7]Yaoxing Huang, [8]Sarah J Schlesinger, [9]Chae Gyu Park, [10]Michel C Nussenzweig, [11]Angela Granelli-Piperno, [12]Ralph Steinman [Full author list] | Journal of Experimental Medicine [missing] | DOI: 10.1084/JEM.20052005 [ORCID]
PubMed: 16505141 [ORCID]
| antibody [missing]; vaccine [missing]; dendritic cell [missing] | 2006-02-27 | |
| The HIV-1 vaccine race | [1]David D Ho, [2]Yaoxing Huang [Full author list] | Cell [missing] | DOI: 10.1016/S0092-8674(02)00832-2 [ORCID]
PubMed: 12150921 [ORCID]
| vaccine [missing] | 2002-07-01 | |
| CD4+ lymphocytopenia in acute infection of Asian macaques by a vaginally transmissible subtype-C, CCR5-tropic Simian/Human Immunodeficiency Virus (SHIV). | [1]Zhiwei Chen, [2]Xiuqing Zhao, [3]Yaoxing Huang, [4]Agegnehu Gettie, [5]Lei Ba, [6]James Blanchard, [7]David D Ho [Full author list] | Journal of Acquired Immune Deficiency Syndromes [missing] | DOI: 10.1097/00042560-200206010-00001 [ORCID]
PubMed: 12045675 [ORCID]
| | 2002-06-01 | |