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Potential publications

165 publications found

Click here for rougher clustering.

Clifford V Harding|W Henry Boom

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Mycobacterium tuberculosis ManLAM inhibits T-cell-receptor signaling by interference with ZAP-70, Lck and LAT phosphorylation[1]Robert N Mahon, [2]Obondo J Sande, [3]Roxana E Rojas, [4]Alan D Levine, [5]Clifford V Harding, [6]W Henry Boom [Full author list]Cellular Immunology [curation]DOI: 10.1016/J.CELLIMM.2012.02.009 [ORCID]
PubMed: 22507872 [ORCID]
Mycobacterium tuberculosis [curation]; phosphorylation [curation]2012-01-01
Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors[1]Clifford V Harding, [2]W Henry Boom [Full author list]Nature Reviews Microbiology [curation]DOI: 10.1038/NRMICRO2321 [ORCID]
PubMed: 20234378 [ORCID]
Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2010-04-01
Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling[1]Robert N Mahon, [2]Roxana E Rojas, [3]Scott A Fulton, [4]Jennifer L Franko, [5]Clifford V Harding, [6]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00222-09 [ORCID]
PubMed: 19651854 [ORCID]
cell wall [curation]; Mycobacterium tuberculosis [curation]2009-08-03
Modulation of pulmonary dendritic cell function during mycobacterial infection[1]Mursalin M Anis, [2]Scott A Fulton, [3]Scott M Reba, [4]Yi Liu, [5]Clifford V Harding, [6]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.01079-07 [ORCID]
PubMed: 18039834 [ORCID]
2007-11-26
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection[1]Mursalin M Anis, [2]Scott A Fulton, [3]Scott M Reba, [4]Clifford V Harding, [5]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.01709-06 [ORCID]
PubMed: 17296758 [ORCID]
2007-02-12
Phosphatidylinositol mannoside from Mycobacterium tuberculosis binds alpha5beta1 integrin (VLA-5) on CD4+ T cells and induces adhesion to fibronectin[1]Roxana E Rojas, [2]Jeremy J Thomas, [3]Adam J Gehring, [4]Preston J Hill, [5]John T Belisle, [6]Clifford V Harding, [7]W Henry Boom [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.177.5.2959 [ORCID]
PubMed: 16920931 [ORCID]
Mycobacterium tuberculosis [curation]2006-09-01
Interferon-alphabeta mediates partial control of early pulmonary Mycobacterium bovis bacillus Calmette-Guérin infection[1]John G. Kuchtey, [2]Scott A Fulton, [3]Scott M Reba, [4]Clifford V Harding, [5]W Henry Boom [Full author list]Immunology [curation]DOI: 10.1111/J.1365-2567.2006.02337.X [ORCID]
PubMed: 16630021 [ORCID]
Mycobacterium bovis [curation]2006-05-01
Role of phagosomes and major histocompatibility complex class II (MHC-II) compartment in MHC-II antigen processing of Mycobacterium tuberculosis in human macrophages[1]Martha Torres, [2]Lakshmi Ramachandra, [3]Roxana E Rojas, [4]Karen Bobadilla, [5]Jeremy Thomas, [6]David H Canaday, [7]Clifford V Harding, [8]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.74.3.1621-1630.2006 [ORCID]
PubMed: 16495533 [ORCID]
Mycobacterium tuberculosis [curation]2006-03-01
Mycobacterium tuberculosis LprG (Rv1411c): a novel TLR-2 ligand that inhibits human macrophage class II MHC antigen processing.[1]Adam J Gehring, [2]Karen M Dobos, [3]John T Belisle, [4]Clifford V Harding, [5]W Henry Boom [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.173.4.2660 [ORCID]
PubMed: 15294983 [ORCID]
Mycobacterium tuberculosis [curation]; macrophage [curation]2004-08-01
Inhibition of major histocompatibility complex II expression and antigen processing in murine alveolar macrophages by Mycobacterium bovis BCG and the 19-kilodalton mycobacterial lipoprotein[1]Scott A Fulton, [2]Scott M Reba, [3]Rish K Pai, [4]Meghan Pennini, [5]Martha Torres, [6]Clifford V Harding, [7]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.72.4.2101-2110.2004 [ORCID]
PubMed: 15039332 [ORCID]
lipoprotein [curation]; Mycobacterium bovis [curation]; macrophage [curation]2004-04-01
T-cell hybridomas from HLA-transgenic mice as tools for analysis of human antigen processing[1]David H Canaday, [2]Adam Gehring, [3]Ethan G Leonard, [4]Brandon Eilertson, [5]John R Schreiber, [6]Clifford V Harding, [7]W Henry Boom [Full author list]Journal of Immunological Methods [curation]DOI: 10.1016/J.JIM.2003.07.004 [ORCID]
PubMed: 14580887 [ORCID]
2003-10-01
The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2.[1]Adam J Gehring, [2]Roxana E Rojas, [3]David H Canaday, [4]David L Lakey, [5]Clifford V Harding, [6]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.71.8.4487-4497.2003 [ORCID]
PubMed: 12874328 [ORCID]
Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2003-08-01
Phosphoantigen presentation by macrophages to mycobacterium tuberculosis--reactive Vgamma9Vdelta2+ T cells: modulation by chloroquine[1]Roxana E Rojas, [2]Martha Torres, [3]Jean-Jacques Fournié, [4]Clifford V Harding, [5]W Henry Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.70.8.4019-4027.2002 [ORCID]
PubMed: 12117907 [ORCID]
tuberculosis [curation]; Mycobacterium tuberculosis [curation]; chloroquine [curation]2002-08-01

Harriet Mayanja-Kizza|W Henry Boom|Catherine M Stein

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda[1]Ningning Ma, [2]Sarah Zalwango, [3]LaShaunda L Malone, [4]Mary Nsereko, [5]Eddie M Wampande, [6]Bonnie A Thiel, [7]Brenda Okware, [8]Robert P Igo, [9]Moses Joloba, [10]Ezekiel Mupere, [11]Harriet Mayanja-Kizza, [12]W Henry Boom, [13]Catherine M Stein, [14]Tuberculosis Research Unit (TBRU) [Full author list]BMC Infectious Diseases [curation]DOI: 10.1186/1471-2334-14-352 [ORCID]
PubMed: 24970328 [ORCID]
Uganda [curation]; tuberculosis [curation]; Mycobacterium tuberculosis [curation]2014-06-27
Genetic and shared environmental influences on interferon-γ production in response to Mycobacterium tuberculosis antigens in a Ugandan population[1]Li Tao, [2]Sarah Zalwango, [3]Keith Chervenak, [4]Bonnie Thiel, [5]Lashaunda L Malone, [6]Feiyou Qiu, [7]Harriet Mayanja-Kizza, [8]W Henry Boom, [9]Catherine M Stein, [10]Tuberculosis Research Unit (TBRU) [Full author list]American Journal of Tropical Medicine and Hygiene [curation]DOI: 10.4269/AJTMH.12-0670 [ORCID]
PubMed: 23629934 [ORCID]
Uganda [curation]; population genetics [curation]; Mycobacterium tuberculosis [curation]2013-04-29
Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study[1]Allison R Baker, [2]Sarah Zalwango, [3]LaShaunda L Malone, [4]Robert P Igo, [5]Feiyou Qiu, [6]Mary Nsereko, [7]Mark D Adams, [8]Pamela Supelak, [9]Harriet Mayanja-Kizza, [10]W Henry Boom, [11]Catherine M Stein [Full author list]Human Immunology [curation]DOI: 10.1016/J.HUMIMM.2011.02.016 [ORCID]
PubMed: 21354459 [ORCID]
Uganda [curation]; tuberculosis [curation]2011-02-25

Thomas R Hawn|W Henry Boom

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Importance of Study Design and Phenotype Definition in Ongoing Studies of Resistance to Latent Mycobacterium tuberculosis Infection[1]Catherine M Stein, [2]Harriet Mayanja-Kizza, [3]Thomas R Hawn, [4]W Henry Boom [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/JIZ539 [ORCID]
PubMed: 31665355 [ORCID]
phenotype [curation]; Mycobacterium tuberculosis [curation]2020-03-01
Long-term stability of resistance to latent M. tuberculosis infection in highly exposed TB household contacts in Kampala, Uganda[1]Catherine M Stein, [2]Mary Nsereko, [3]LaShaunda L Malone, [4]Brenda Okware, [5]Hussein Kisingo, [6]Sophie Nalukwago, [7]Keith Chervenak, [8]Harriet Mayanja-Kizza, [9]Thomas R Hawn, [10]W Henry Boom [Full author list]Clinical Infectious Diseases [curation]PubMed: 30165605 [ORCID]
Uganda [curation]; Mycobacterium tuberculosis [curation]2018-08-28
Long-term Stability of Resistance to Latent Mycobacterium tuberculosis Infection in Highly Exposed Tuberculosis Household Contacts in Kampala, Uganda[1]Catherine M Stein, [2]Mary Nsereko, [3]LaShaunda L Malone, [4]Brenda Okware, [5]Hussein Kisingo, [6]Sophie Nalukwago, [7]Keith Chervenak, [8]Harriet Mayanja-Kizza, [9]Thomas R Hawn, [10]W Henry Boom [Full author list]Clinical Infectious Diseases [curation]DOI: 10.1093/CID/CIY751 [ORCID]
Uganda [curation]; tuberculosis [curation]; Mycobacterium tuberculosis [curation]2018-08-28

Misc

TitleAuthors (identified)Published InIdentifier(s)TopicPublished DateMatch?
Insights into the L,D-transpeptidases and D,D-carboxypeptidase of Mycobacterium abscessus: ceftaroline, imipenem and novel diazabicyclooctanes inhibitors[1]Khalid M Dousa, [2]Sebastian G Kurz, [3]Magdalena A Taracila, [4]Tracey Bonfield, [5]Christopher R Bethel, [6]Melissa D Barnes, [7]Suresh Selvaraju, [8]Ayman M Abdelhamed, [9]Barry N Kreiswirth, [10]W Henry Boom, [11]Shannon H Kasperbauer, [12]Charles L Daley, [13]Robert A Bonomo [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.00098-20 [ORCID]
PubMed: 32393499 [ORCID]
Mycobacterium abscessus [curation]2020-05-11
Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?[1]Michael L McHenry, [2]Jacquelaine Bartlett, [3]Robert P Igo, [4]Eddie M Wampande, [5]Penelope Benchek, [6]Harriet Mayanja-Kizza, [7]Kyle Fluegge, [8]Noemi B Hall, [9]Sébastien Gagneux, [10]Sarah Tishkoff, [11]Christian Morberg Wejse, [12]Giorgio Sirugo, [13]W Henry Boom, [14]Moses Joloba, [15]Scott M Williams, [16]Catherine M Stein [Full author list]PLOS Genetics [curation]DOI: 10.1371/JOURNAL.PGEN.1008728 [ORCID]
PubMed: 32352966 [ORCID]
tuberculosis [curation]; Mycobacterium tuberculosis [curation]2020-04-30
Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda[1]Eddie M Wampande, [2]Peter Naniima, [3]Ezekiel Mupere, [4]David P Kateete, [5]LaShaunda L Malone, [6]Catherine M Stein, [7]Harriet Mayanja-Kizza, [8]Sébastien Gagneux, [9]W Henry Boom, [10]Moses Joloba [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0221644 [ORCID]
PubMed: 31498808 [ORCID]
Uganda [curation]; Mycobacterium tuberculosis [curation]2019-09-09
Distinct serum biosignatures are associated with different tuberculosis treatment outcomes[1]Katharina Ronacher, [2]Novel N Chegou, [3]Léanie Kleynhans, [4]Joel F Djoba Siawaya, [5]Nelita Du Plessis, [6]André G Loxton, [7]Elizna Maasdorp, [8]Gerard Tromp, [9]Martin Kidd, [10]Kim Stanley, ..., [19]John T Belisle, [20]Jacqueline M Cliff, [21]W Henry Boom, [22]John L Johnson, [23]Paul van Helden, ... [Full author list]Tuberculosis [curation]DOI: 10.1016/J.TUBE.2019.101859 [ORCID]
PubMed: 31434026 [ORCID]
2019-08-12
Recognition of CD8+ T-cell epitopes to identify adults with pulmonary tuberculosis[1]Christina Lancioni, [2]Gwendolyn M Swarbrick, [3]Byung Park, [4]Melissa Nyendak, [5]Mary Nsereko, [6]Harriet Mayanja-Kizza, [7]Megan D Null, [8]Meghan E Cansler, [9]Rowan B Duncan, [10]Joy Baseke, [11]Keith Chervenak, [12]LaShaunda Malone, [13]Emily G Heaphy, [14]W Henry Boom, [15]David M Lewinsohn, [16]Deborah A Lewinsohn [Full author list]European Respiratory Journal [curation]DOI: 10.1183/13993003.02053-2018 [ORCID]
PubMed: 30923183 [ORCID]
pulmonary tuberculosis [curation]2019-05-30
Immune activation and regulatory T cells in Mycobacterium tuberculosis infected lymph nodes[1]Karima Sahmoudi, [2]Hassan Abbassi, [3]Nada Bouklata, [4]Mohamed Nouredine El Alami, [5]Abderrahmane Sadak, [6]Christopher Burant, [7]W Henry Boom, [8]Rajae El Aouad, [9]David H Canaday, [10]Fouad Seghrouchni [Full author list]BMC Immunology [curation]DOI: 10.1186/S12865-018-0266-8 [ORCID]
PubMed: 30409122 [ORCID]
Mycobacterium tuberculosis [curation]; lymph node [curation]2018-11-08
Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes[1]Supriya Shukla, [2]Edward T Richardson, [3]Michael G Drage, [4]W Henry Boom, [5]Clifford V Harding [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00450-18 [ORCID]
PubMed: 30037791 [ORCID]
Mycobacterium tuberculosis [curation]2018-09-21
Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection[1]Jason D Simmons, [2]Catherine M Stein, [3]Chetan Seshadri, [4]Monica Campo, [5]Galit Alter, [6]Sarah Fortune, [7]Erwin Schurr, [8]Robert S Wallis, [9]Gavin J Churchyard, [10]Harriet Mayanja-Kizza, [11]W Henry Boom, [12]Thomas R Hawn [Full author list]Nature Reviews Immunology [curation]DOI: 10.1038/S41577-018-0025-3 [ORCID]
PubMed: 29895826 [ORCID]
Mycobacterium tuberculosis [curation]2018-09-01
Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants[1]Robert P Igo, [2]Noémi B Hall, [3]LaShaunda L Malone, [4]Jacob B Hall, [5]Barbara Truitt, [6]Feiyou Qiu, [7]Li Tao, [8]Ezekiel Mupere, [9]Audrey Schnell, [10]Thomas R Hawn, [11]William S Bush, [12]Moses Joloba, [13]W Henry Boom, [14]Catherine M Stein [Full author list]Genes and Immunity [curation]DOI: 10.1038/S41435-018-0040-1 [ORCID]
PubMed: 30100616 [ORCID]
Uganda [curation]; Mycobacterium tuberculosis [curation]2018-08-13
Bacterial Factors That Predict Relapse after Tuberculosis Therapy[1]Roberto Colangeli, [2]Hannah Jedrey, [3]Soyeon Kim, [4]Roy Connell, [5]Shuyi Ma, [6]Uma D Chippada Venkata, [7]Soumitesh Chakravorty, [8]Aditi Gupta, [9]Erin E Sizemore, [10]Lois Diem, [11]David R Sherman, [12]Alphonse Okwera, [13]Reynaldo Dietze, [14]W Henry Boom, [15]John L Johnson, [16]William R Mac Kenzie, [17]David Alland, [18]DMID 01-009/Tuberculosis Trials Consortium Study 22 Teams [Full author list]The New England Journal of Medicine [curation]DOI: 10.1056/NEJMOA1715849 [ORCID]
PubMed: 30157391 [ORCID]
tuberculosis [curation]2018-08-01
Impact of geographic distance on appraisal delay for active TB treatment seeking in Uganda: a network analysis of the Kawempe Community Health Cohort Study.[1]Kyle Fluegge, [2]LaShaunda L Malone, [3]Mary Nsereko, [4]Brenda Okware, [5]Christian Morberg Wejse, [6]Hussein Kisingo, [7]Ezekiel Mupere, [8]W Henry Boom, [9]Catherine M Stein [Full author list]BMC Public Health [curation]DOI: 10.1186/S12889-018-5648-6 [ORCID]
PubMed: 29940918 [ORCID]
Uganda [curation]; community health [curation]2018-06-26
A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts.[1]Fergal Duffy, [2]Ethan Thompson, [3]Katrina Downing, [4]Sara Suliman, [5]Harriet Mayanja-Kizza, [6]W Henry Boom, [7]Bonnie Thiel, [8]January Weiner Iii, [9]Stefan H E Kaufmann, [10]Drew Dover, [11]David Tabb, [12]Hazel Dockrell, [13]Tom H M Ottenhoff, [14]Gerard Tromp, [15]Thomas J Scriba, [16]Daniel E Zak, [17]Gerhard Walzl, [18]GC6-74 Consortium [Full author list]Frontiers in Immunology [curation]DOI: 10.3389/FIMMU.2018.00661 [ORCID]
PubMed: 29706954 [ORCID]
2018-04-13
Four-gene Pan-African Blood Signature Predicts Progression to Tuberculosis.[1]Sara Suliman, [2]Ethan Thompson, [3]Jayne S. Sutherland, [4]January Weiner Rd, [5]Martin O C Ota, [6]Smitha Shankar, [7]Adam Penn-Nicholson, [8]Bonnie Thiel, [9]Mzwandile Erasmus, [10]Jeroen Maertzdorf, ..., [23]Rawleigh Howe, [24]Harriet Mayanja-Kizza, [25]W Henry Boom, [26]Hazel Dockrell, [27]Tom H M Ottenhoff, ... [Full author list]American Journal of Respiratory and Critical Care Medicine [curation]DOI: 10.1164/RCCM.201711-2340OC [ORCID]
PubMed: 29624071 [ORCID]
tuberculosis [curation]2018-04-06
Resistance and Susceptibility to Mycobacterium Tuberculosis Infection and Disease in Tuberculosis Households in Kampala, Uganda.[1]Catherine M Stein, [2]Sarah Zalwango, [3]LaShaunda L Malone, [4]Bonnie Thiel, [5]Ezekiel Mupere, [6]Mary Nsereko, [7]Brenda Okware, [8]Hussein Kisingo, [9]Christina L Lancioni, [10]Charles M Bark, [11]Christopher C Whalen, [12]Moses Joloba, [13]W Henry Boom, [14]Harriet Mayanja-Kizza [Full author list]American Journal of Epidemiology [curation]DOI: 10.1093/AJE/KWX380 [ORCID]
PubMed: 29304247 [ORCID]
Uganda [curation]; tuberculosis [curation]; Mycobacterium tuberculosis [curation]2018-01-03
Effectiveness of WHO's pragmatic screening algorithm for child contacts of tuberculosis cases in resource-constrained settings: a prospective cohort study in Uganda[1]Leonardo Martinez, [2]Ye Shen, [3]Andreas Handel, [4]Srijita Chakraburty, [5]Catherine M Stein, [6]LaShaunda L Malone, [7]W Henry Boom, [8]Frederick D Quinn, [9]Moses Joloba, [10]Christopher C Whalen, [11]Sarah Zalwango [Full author list]The Lancet. Respiratory medicine [curation]DOI: 10.1016/S2213-2600(17)30497-6 [ORCID]
PubMed: 29273539 [ORCID]
Uganda [curation]2017-12-19
The effect of interrupted anti-retroviral treatment on the reconstitution of memory and naive T cells during tuberculosis treatment in HIV patients with active pulmonary tuberculosis[1]Sophie Nalukwago, [2]Christina L Lancioni, [3]Joy Baseke Oketcho, [4]Dave H E Canaday, [5]W Henry Boom, [6]Lonzy Ojok, [7]Harriet Mayanja-Kizza [Full author list]African Health Sciences [curation]DOI: 10.4314/AHS.V17I4.2 [ORCID]
PubMed: 29937865 [ORCID]
tuberculosis [curation]; pulmonary tuberculosis [curation]2017-12-01
Genomics of human pulmonary tuberculosis: from genes to pathways.[1]Catherine M Stein, [2]Lindsay Sausville, [3]Christian Morberg Wejse, [4]Rafal S Sobota, [5]Nicola M Zetola, [6]Philip C Hill, [7]W Henry Boom, [8]William K Scott, [9]Giorgio Sirugo, [10]Scott M Williams [Full author list]Current genetic medicine reports [curation]DOI: 10.1007/S40142-017-0130-9 [ORCID]
PubMed: 29805915 [ORCID]
genomics [curation]; pulmonary tuberculosis [curation]2017-10-12
Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan[1]Ahmad F Karim, [2]Obondo J Sande, [3]Sara E Tomechko, [4]Xuedong Ding, [5]M Li, [6]Sean Maxwell, [7]Rob Ewing, [8]Clifford V Harding, [9]Roxana E Rojas, [10]Mark R Chance, [11]W Henry Boom [Full author list]Proteomics [curation]DOI: 10.1002/PMIC.201700233 [ORCID]
PubMed: 28994205 [ORCID]
Mycobacterium tuberculosis [curation]; Lipoarabinomannan [curation]2017-10-10
Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function[1]Ahmad Faisal Karim, [2]Scott M Reba, [3]Qing Li, [4]W Henry Boom, [5]Roxana E Rojas [Full author list]European Journal of Immunology [curation]DOI: 10.1002/EJI.201646846 [ORCID]
PubMed: 28665005 [ORCID]
toll-like receptor [curation]2017-06-30
Comprehensive definition of human immunodominant CD8 antigens in tuberculosis[1]Deborah A Lewinsohn, [2]Gwendolyn M Swarbrick, [3]Byung Park, [4]Meghan E Cansler, [5]Megan D Null, [6]Katelynne G Toren, [7]Joy Baseke, [8]Sarah Zalwango, [9]Harriet Mayanja-Kizza, [10]LaShaunda L Malone, [11]Melissa Nyendak, [12]Guanming Wu, [13]Kristi Guinn, [14]Shannon McWeeney, [15]Tomi Mori, [16]Keith A Chervenak, [17]David R Sherman, [18]W Henry Boom, [19]David M Lewinsohn [Full author list]NPJ Vaccines [curation]DOI: 10.1038/S41541-017-0008-6 [ORCID]
PubMed: 28775896 [ORCID]
tuberculosis [curation]2017-04-03
Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages[1]David Stucki, [2]Daniela Brites, [3]Leïla Jeljeli, [4]Mireia Coscolla, [5]Qingyun Liu, [6]Andrej Trauner, [7]Lukas Fenner, [8]Liliana Rutaihwa, [9]Sonia Borrell, [10]Tao Luo, ..., [27]Willy Ssengooba, [28]Moses Joloba, [29]W Henry Boom, [30]Indira Basu, [31]James Bower, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG.3704 [ORCID]
PubMed: 27798628 [ORCID]
Mycobacterium tuberculosis [curation]2016-10-31
Human leukocyte antigen class 1 genotype distribution and analysis in persons with active tuberculosis and household contacts from Central Uganda[1]Helen Koyokoyo Buteme, [2]Rebecca Axelsson-Robertson, [3]Lina Benson, [4]Moses Joloba, [5]W Henry Boom, [6]Gunilla Källenius, [7]Markus Maeurer [Full author list]BMC Infectious Diseases [curation]DOI: 10.1186/S12879-016-1833-3 [ORCID]
PubMed: 27659198 [ORCID]
Uganda [curation]2016-09-23
Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses[1]Sara Suliman, [2]Hennie Geldenhuys, [3]John L Johnson, [4]Jane E Hughes, [5]Erica Smit, [6]Melissa Murphy, [7]Asma Toefy, [8]Lesedi Lerumo, [9]Christiaan Hopley, [10]Bernadette Pienaar, [11]Phalkun Chheng, [12]Elisa Nemes, [13]Daniel F Hoft, [14]Willem Albert Hanekom, [15]W Henry Boom, [16]Mark Hatherill, [17]Thomas J Scriba [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1501996 [ORCID]
PubMed: 27412415 [ORCID]
Mycobacterium tuberculosis [curation]2016-07-13
Proteomic and bioinformatics profile of paired human alveolar macrophages and peripheral blood monocytes[1]Sara E Tomechko, [2]Kathleen C Lundberg, [3]Jessica Jarvela, [4]Gurkan Bebek, [5]Nicole G Chesnokov, [6]Daniela Schlatzer, [7]Rob Ewing, [8]W Henry Boom, [9]Mark R Chance, [10]Richard F Silver [Full author list]Proteomics [curation]DOI: 10.1002/PMIC.201400496 [ORCID]
PubMed: 26389541 [ORCID]
bioinformatics [curation]2015-11-01
Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis[1]Leonardo Martinez, [2]Olivia Cords, [3]Qiao Liu, [4]Carlos Acuna-Villaorduna, [5]Maryline Bonnet, [6]Greg J Fox, [7]Anna Cristina C Carvalho, [8]Pei-Chun Chan, [9]Julio Croda, [10]Philip C Hill, ..., [43]Fadila Boulahbal, [44]Chi-Tai Fang, [45]W Henry Boom, [46]Eduardo Martins Netto, [47]Antonio Carlos Lemos, ... [Full author list]The Lancet Global Health [curation]DOI: 10.1016/S2214-109X(22)00283-2 [ORCID]
2022-09-01
Identification of Host Proteins Predictive of Early Stage Mycobacterium tuberculosis Infection[1]Charles M Bark, [2]Ameur M Manceur, [3]LaShaunda L Malone, [4]Mary Nsereko, [5]Brenda Okware, [6]Harriet K Mayanja, [7]Moses Joloba, [8]Isabelle Rajotte, [9]Marija Mentinova, [10]Phyla Kay, [11]Seydina Lo, [12]Patrick Tremblay, [13]Catherine M Stein, [14]W Henry Boom, [15]Eustache Paramithiotis [Full author list]EBioMedicine [curation]DOI: 10.1016/J.EBIOM.2017.06.019 [ORCID]
PubMed: 28655597 [ORCID]
Mycobacterium tuberculosis [curation]2017-06-20
Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda[1]Samira Joussef-Piña, [2]Immaculate Nankya, [3]Sophie Nalukwago, [4]Joy Baseke, [5]Sandra Rwambuya, [6]Dane Winner, [7]Fred Kyeyune, [8]Keith Chervenak, [9]Bonnie Thiel, [10]Robert Asaad, [11]Curtis Dobrowolski, [12]Benjamin Luttge, [13]Blair Lawley, [14]Cissy M Kityo, [15]W Henry Boom, [16]Jonathan Karn, [17]Miguel E Quiñones-Mateu [Full author list]Retrovirology [curation]DOI: 10.1186/S12977-022-00587-3 [ORCID]
PubMed: 35033105 [ORCID]
2022-01-15
Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection[1]Chetan Seshadri, [2]Nafiseh Sedaghat, [3]Monica Campo, [4]Glenna Peterson, [5]Richard D Wells, [6]Gregory S Olson, [7]David R Sherman, [8]Catherine M Stein, [9]Harriet Mayanja-Kizza, [10]Ali Shojaie, [11]W Henry Boom, [12]Thomas R Hawn, [13]Tuberculosis Research Unit (TBRU) [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0175844 [ORCID]
PubMed: 28414762 [ORCID]
Mycobacterium tuberculosis [curation]2017-04-17
Early Bactericidal Activity of AZD5847 in Patients with Pulmonary Tuberculosis[1]Jennifer Furin, [2]Jeannine Du Bois, [3]Elana van Brakel, [4]Phalkun Chheng, [5]Amour Venter, [6]Charles A Peloquin, [7]Abdullah Alsultan, [8]Bonnie A Thiel, [9]Sara M Debanne, [10]W Henry Boom, [11]Andreas H Diacon, [12]John L Johnson [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.01163-16 [ORCID]
PubMed: 27550361 [ORCID]
tuberculosis [curation]; pulmonary tuberculosis [curation]2016-08-22
A blood RNA signature for tuberculosis disease risk: a prospective cohort study[1]Daniel E Zak, [2]Adam Penn-Nicholson, [3]Thomas J Scriba, [4]Ethan Thompson, [5]Sara Suliman, [6]Lynn M Amon, [7]Hassan Mahomed, [8]Mzwandile Erasmus, [9]Wendy Whatney, [10]Gregory D Hussey, ..., [18]Rawleigh Howe, [19]Hazel Dockrell, [20]W Henry Boom, [21]Bonnie Thiel, [22]Tom H M Ottenhoff, ... [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(15)01316-1 [ORCID]
PubMed: 27017310 [ORCID]
tuberculosis [curation]2016-03-23
Activity of nitazoxanide and tizoxanide against Mycobacterium tuberculosis in vitro and in whole blood culture[1]Elizabeth P Harausz, [2]Keith A Chervenak, [3]Caryn E Good, [4]Michael R Jacobs, [5]Robert S Wallis, [6]Manuel Vincente Sanchez-Felix, [7]W Henry Boom, [8]TB Research Unit (TBRU) at Case Western Reserve University [Full author list]Tuberculosis [curation]DOI: 10.1016/J.TUBE.2016.03.002 [ORCID]
PubMed: 27156623 [ORCID]
Mycobacterium tuberculosis [curation]; whole blood [curation]2016-03-22
Tuberculosis case finding in first-degree relative contacts not living with index tuberculosis cases in Kampala, Uganda[1]Phalkun Chheng, [2]Mary Nsereko, [3]LaShaunda L Malone, [4]Brenda Okware, [5]Sarah Zalwango, [6]Moses Joloba, [7]W Henry Boom, [8]Ezekiel Mupere, [9]Catherine M Stein [Full author list]Clinical Epidemiology [curation]DOI: 10.2147/CLEP.S82389 [ORCID]
PubMed: 26508888 [ORCID]
Uganda [curation]; tuberculosis [curation]2015-10-13
Incubation time of Mycobacterium tuberculosis complex sputum cultures in BACTEC MGIT 960: 4weeks of negative culture is enough for physicians to consider alternative diagnoses[1]Sam Ogwang, [2]Paul Mubiri, [3]Charles M Bark, [4]Moses Joloba, [5]W Henry Boom, [6]John L Johnson [Full author list]Diagnostic Microbiology and Infectious Disease [curation]DOI: 10.1016/J.DIAGMICROBIO.2015.07.002 [ORCID]
PubMed: 26239846 [ORCID]
Mycobacterium tuberculosis [curation]; sputum [curation]2015-07-09
Methylome-wide analysis reveals epigenetic marks associated with resistance to tuberculosis in HIV-infected individuals from East Africa[1]Catherine M Stein, [2]Penelope Benchek, [3]Jacquelaine Bartlett, [4]Robert P Igo, [5]Rafal S Sobota, [6]Keith Chervenak, [7]Harriet Mayanja-Kizza, [8]C. Fordham von Reyn, [9]Timothy Lahey, [10]William S Bush, [11]W Henry Boom, [12]William K Scott, [13]Carmen Marsit, [14]Giorgio Sirugo, [15]Scott M Williams [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/JIAA785 [ORCID]
PubMed: 33400784 [ORCID]
2021-01-05
TLR2-Tpl2-dependent ERK Signaling Drives Inverse Regulation of IL-12 in Dendritic Cells and Macrophages[1]Sarah G Groft, [2]Nancy Nagy, [3]W Henry Boom, [4]Clifford V Harding [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00323-20 [ORCID]
PubMed: 33077627 [ORCID]
dendritic cell [curation]2020-10-19
ERK Signaling Is Essential for Macrophage Development.[1]Edward T Richardson, [2]Supriya Shukla, [3]Nancy Nagy, [4]W Henry Boom, [5]Rose C Beck, [6]Lan Zhou, [7]Gary E Landreth, [8]Clifford V Harding [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0140064 [ORCID]
PubMed: 26445168 [ORCID]
2015-10-07
A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents[1]Chelsea Carpenter, [2]John Sidney, [3]Ravi V Kolla, [4]Kaustuv Nayak, [5]Helena I. Tomiyama, [6]Claudia Tomiyama, [7]Oscar A Padilla, [8]Virginie Rozot, [9]Syed F Ahamed, [10]Carlos Ponte, ..., [24]Mayuko Saito, [25]Julie McElrath, [26]W Henry Boom, [27]Delia Goletti, [28]Robert H Gilman, ... [Full author list]Tuberculosis [curation]DOI: 10.1016/J.TUBE.2015.07.001 [ORCID]
PubMed: 26277695 [ORCID]
Mycobacterium tuberculosis [curation]2015-08-01
Sulfamethoxazole susceptibility of Mycobacterium tuberculosis isolates from HIV-infected Ugandan adults with tuberculosis taking trimethoprim-sulfamethoxazole prophylaxis[1]Sam Ogwang, [2]Caryn E Good, [3]Brenda Okware, [4]Mary Nsereko, [5]Michael R Jacobs, [6]W Henry Boom, [7]Charles M Bark [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.01101-15 [ORCID]
PubMed: 26169400 [ORCID]
Uganda [curation]; tuberculosis [curation]; Mycobacterium tuberculosis [curation]2015-07-13
Bacterial Membrane Vesicles Mediate the Release of Mycobacterium tuberculosis Lipoglycans and Lipoproteins from Infected Macrophages[1]Jaffre J Athman, [2]Ying Wang, [3]David J McDonald, [4]W Henry Boom, [5]Clifford V Harding, [6]Pamela A. Wearsch [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1402894 [ORCID]
PubMed: 26109643 [ORCID]
Mycobacterium tuberculosis [curation]; macrophage [curation]2015-06-24
Toll-like receptor 2-dependent extracellular signal-regulated kinase signaling in Mycobacterium tuberculosis-infected macrophages drives anti-inflammatory responses and inhibits Th1 polarization of responding T cells[1]Edward T Richardson, [2]Supriya Shukla, [3]David R Sweet, [4]Pamela A. Wearsch, [5]Philip N Tsichlis, [6]W Henry Boom, [7]Clifford V Harding [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00135-15 [ORCID]
PubMed: 25776754 [ORCID]
Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2015-03-16
Comparison of MGIT and Myco/F lytic liquid-based blood culture systems for recovery of Mycobacterium tuberculosis from pleural fluid[1]Elizabeth Harausz, [2]John Kafuluma Lusiba, [3]Mary Nsereko, [4]John L Johnson, [5]Zahra Toossi, [6]Sam Ogwang, [7]W Henry Boom, [8]Moses Joloba, [9]Tuberculosis Research Unit (TBRU) [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.02742-14 [ORCID]
PubMed: 25653400 [ORCID]
Mycobacterium tuberculosis [curation]2015-02-04
Polymorphisms in TICAM2 and IL1B are associated with TB.[1]Noémi Borsay Hall, [2]Robert P Igo, [3]LaShaunda L Malone, [4]Barbara Truitt, [5]Audrey Schnell, [6]Li Tao, [7]Brenda Okware, [8]Mary Nsereko, [9]Keith Chervenak, [10]Christina Lancioni, [11]Thomas R Hawn, [12]Harriet Mayanja-Kizza, [13]Moses Joloba, [14]W Henry Boom, [15]Catherine M Stein, [16]Tuberculosis Research Unit (TBRU) [Full author list]Genes and Immunity [curation]DOI: 10.1038/GENE.2014.77 [ORCID]
PubMed: 25521228 [ORCID]
2014-12-18
Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion[1]Supriya Shukla, [2]Edward T Richardson, [3]Jaffre J Athman, [4]Libin Shi, [5]Pamela A. Wearsch, [6]David McDonald, [7]Niaz Banaei, [8]W Henry Boom, [9]Mary Jackson, [10]Clifford V Harding [Full author list]PLOS Pathogens [curation]DOI: 10.1371/JOURNAL.PPAT.1004471 [ORCID]
PubMed: 25356793 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; Lipoarabinomannan [curation]2014-10-30
Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection[1]Zhuoming Liu, [2]Scott Reba, [3]Wei-Dong Chen, [4]Suheel Kumar Porwal, [5]W Henry Boom, [6]Robert B Petersen, [7]Roxana Rojas, [8]Rajesh Viswanathan, [9]L Devireddy [Full author list]Journal of Experimental Medicine [curation]DOI: 10.1084/JEM.20132629 [ORCID]
PubMed: 24863067 [ORCID]
2014-05-26
Safety and reactogenicity of BCG revaccination with isoniazid pretreatment in TST positive adults[1]Mark Hatherill, [2]Hendrik Geldenhuys, [3]Bernadette Pienaar, [4]Sara Suliman, [5]Phalkun Chheng, [6]Sara M Debanne, [7]Daniel F Hoft, [8]W Henry Boom, [9]Willem Albert Hanekom, [10]John L Johnson [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2014.04.084 [ORCID]
PubMed: 24814553 [ORCID]
isoniazid [curation]; booster dose [curation]2014-05-09
Tuberculin skin test reversion following isoniazid preventive therapy reflects diversity of immune response to primary Mycobacterium tuberculosis infection[1]Denise F Johnson, [2]LaShaunda L Malone, [3]Sarah Zalwango, [4]Joy Mukisa Oketcho, [5]Keith A Chervenak, [6]Bonnie Thiel, [7]Harriet Mayanja-Kizza, [8]Catherine M Stein, [9]W Henry Boom, [10]Christina L Lancioni, [11]Tuberculosis Research Unit [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0096613 [ORCID]
PubMed: 24796677 [ORCID]
tuberculin [curation]; biodiversity [curation]; Mycobacterium tuberculosis [curation]; isoniazid [curation]2014-05-05
How we determined the most reliable solid medium for studying treatment of tuberculosis[1]Charles M. Heilig, [2]Pei-Jean I Feng, [3]Moses Joloba, [4]John L Johnson, [5]Karen Morgan, [6]Phineas Gitta, [7]W Henry Boom, [8]Harriet Mayanja-Kizza, [9]Kathleen D Eisenach, [10]Lorna Bozeman, [11]Stefan V Goldberg [Full author list]Tuberculosis [curation]DOI: 10.1016/J.TUBE.2014.02.006 [ORCID]
PubMed: 24661816 [ORCID]
2014-03-04
Effect of isoniazid therapy for latent TB infection on QuantiFERON-TB gold in-tube responses in adults with positive tuberculin skin test results in a high TB incidence area: a controlled study[1]John L Johnson, [2]Hendrik Geldenhuys, [3]Bonnie A Thiel, [4]Asma Toefy, [5]Sara Suliman, [6]Bernadette Pienaar, [7]Phalkun Chheng, [8]Thomas J Scriba, [9]W Henry Boom, [10]Willem Albert Hanekom, [11]Mark Hatherill [Full author list]Chest [curation]DOI: 10.1378/CHEST.13-1232 [ORCID]
PubMed: 24135768 [ORCID]
tuberculin [curation]; isoniazid [curation]2014-03-01
A metabolic biosignature of early response to anti-tuberculosis treatment[1]Sebabrata Mahapatra, [2]Ann M Hess, [3]John L Johnson, [4]Kathleen D Eisenach, [5]Mary A DeGroote, [6]Phineas Gitta, [7]Moses Joloba, [8]Gilla Kaplan, [9]Gerhard Walzl, [10]W Henry Boom, [11]John T Belisle [Full author list]BMC Infectious Diseases [curation]DOI: 10.1186/1471-2334-14-53 [ORCID]
PubMed: 24484441 [ORCID]
tuberculosis [curation]2014-01-31
Wasting among Uganda men with pulmonary tuberculosis is associated with linear regain in lean tissue mass during and after treatment in contrast to women with wasting who regain fat tissue mass: prospective cohort study[1]Ezekiel Mupere, [2]LaShaunda Malone, [3]Sarah Zalwango, [4]Alphonse Okwera, [5]Mary Nsereko, [6]Daniel J Tisch, [7]Isabel M Parraga, [8]Catherine M Stein, [9]Roy Mugerwa, [10]W Henry Boom, [11]Harriet Mayanja-Kizza, [12]Christopher C Whalen, [13]Tuberculosis Research Unit at Case Western Reserve University [Full author list]BMC Infectious Diseases [curation]DOI: 10.1186/1471-2334-14-24 [ORCID]
PubMed: 24410970 [ORCID]
Uganda [curation]; tuberculosis [curation]; pulmonary tuberculosis [curation]2014-01-13
Mycobacterium tuberculosis specific CD8(+) T cells rapidly decline with antituberculosis treatment[1]Melissa R Nyendak, [2]Byung Park, [3]Megan D Null, [4]Joy Baseke, [5]Gwendolyn Swarbrick, [6]Harriet Mayanja-Kizza, [7]Mary Nsereko, [8]Denise F Johnson, [9]Phineas Gitta, [10]Alphonse Okwera, [11]Stefan Goldberg, [12]Lorna Bozeman, [13]John L Johnson, [14]W Henry Boom, [15]Deborah A Lewinsohn, [16]David M. Lewinsohn, [17]Tuberculosis Research Unit and the Tuberculosis Trials Consortium [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0081564 [ORCID]
PubMed: 24324704 [ORCID]
tuberculosis [curation]; Mycobacterium tuberculosis [curation]2013-12-04
Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis[1]David G Dillon, [2]Deepti Gurdasani, [3]Johanna Riha, [4]Kenneth Ekoru, [5]Gershim Asiki, [6]Billy N Mayanja, [7]Naomi S Levitt, [8]Nigel J. Crowther, [9]Moffat Nyirenda, [10]Marina Njelekela, ..., [14]Kathryn M. Anastos, [15]Livio Azzoni, [16]W Henry Boom, [17]Caterina Compostella, [18]Joel A Dave, ... [Full author list]International Journal of Epidemiology [curation]DOI: 10.1093/IJE/DYT198 [ORCID]
PubMed: 24415610 [ORCID]
diabetes [curation]; arterial hypertension [curation]; Sub-Saharan Africa [curation]; systematic review [curation]; highly active antiretroviral therapy [curation]; human immunodeficiency virus infectious disease [curation]; dyslipidemias [curation]2013-12-01
Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity[0]Benjamin M Kagina, [1]J S Sutherland, [2]A G Loxton, [3]M C Haks, [4]D Kassa, [5]L Ambrose, [6]J-S Lee, [7]L Ran, [8]D van Baarle, [9]J Maertzdorf, [10]R Howe, [11]Harriet Mayanja-Kizza, [12]W H Boom, [13]B A Thiel, [14]A C Crampin, ... [Full author list]Clinical Microbiology and Infection [curation]DOI: 10.1111/1469-0691.12383 [ORCID]
PubMed: 24205913 [ORCID]
tuberculosis [curation]2013-11-11
Comparison of time to positive and colony counting in an early bactericidal activity study of anti-tuberculosis treatment[1]C M Bark, [2]P Gitta, [3]S Ogwang, [4]M Nsereko, [5]B A Thiel, [6]W H Boom, [7]K D Eisenach, [8]Moses Joloba, [9]J L Johnson [Full author list]International Journal of Tuberculosis and Lung Disease [curation]DOI: 10.5588/IJTLD.13.0063 [ORCID]
PubMed: 24125449 [ORCID]
tuberculosis [curation]2013-11-01
Contact investigation for active tuberculosis among child contacts in Uganda[1]Devan Jaganath, [2]Sarah Zalwango, [3]Brenda Okware, [4]Mary Nsereko, [5]Hussein Kisingo, [6]LaShaunda Malone, [7]Christina Lancioni, [8]Alphonse Okwera, [9]Moses Joloba, [10]Harriet Mayanja-Kizza, [11]W Henry Boom, [12]Catherine M Stein, [13]Ezekiel Mupere, [14]Tuberculosis Research Unit [Full author list]Clinical Infectious Diseases [curation]DOI: 10.1093/CID/CIT645 [ORCID]
PubMed: 24077055 [ORCID]
Uganda [curation]; tuberculosis [curation]2013-09-27
Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa[1]Jayne S. Sutherland, [2]Maeve K Lalor, [3]Gillian F Black, [4]Lyn R Ambrose, [5]André G. Loxton, [6]Novel N Chegou, [7]Desta Kassa, [8]Adane Mihret, [9]Rawleigh Howe, [10]Harriet Mayanja-Kizza, ..., [15]Michel R Klein, [16]Shreemanta Parida, [17]W Henry Boom, [18]Bonnie A Thiel, [19]Amelia Crampin, ... [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0074080 [ORCID]
PubMed: 24040170 [ORCID]
Mycobacterium tuberculosis [curation]; Sub-Saharan Africa [curation]2013-09-10
Relapse more common than reinfection in recurrent tuberculosis 1-2 years post treatment in urban Uganda[1]H Luzze, [2]D F Johnson, [3]K Dickman, [4]Harriet Mayanja-Kizza, [5]A Okwera, [6]K Eisenach, [7]M D Cave, [8]C C Whalen, [9]J L Johnson, [10]W H Boom, [11]Moses Joloba, [12]Tuberculosis Research Unit [Full author list]International Journal of Tuberculosis and Lung Disease [curation]DOI: 10.5588/IJTLD.11.0692 [ORCID]
PubMed: 23407224 [ORCID]
Uganda [curation]; tuberculosis [curation]2013-03-01
Efficacy and timing of intra-aortic counterpulsation in patients with ST-elevation myocardial infarction complicated by cardiogenic shock[1]K D Sjauw, [2]A E Engström, [3]M M Vis, [4]W Boom, [5]J Baan, [6]R J de Winter, [7]J G P Tijssen, [8]J J Piek, [9]J P S Henriques [Full author list]Netherlands Heart Journal [curation]DOI: 10.1007/S12471-012-0312-8 [ORCID]
PubMed: 22847042 [ORCID]
cardiogenic shock [curation]2012-10-01
Rhomboids of Mycobacteria: characterization using an aarA mutant of Providencia stuartii and gene deletion in Mycobacterium smegmatis[1]David Patrick Kateete, [2]Fred Ashaba Katabazi, [3]Alfred Okeng, [4]Moses Okee, [5]Conrad Musinguzi, [6]Benon Byamugisha Asiimwe, [7]Samuel Kyobe, [8]Jeniffer Asiimwe, [9]W Henry Boom, [10]Moses Joloba [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0045741 [ORCID]
PubMed: 23029216 [ORCID]
Mycobacterium smegmatis [curation]; Providencia stuartii [curation]2012-09-21
Lean tissue mass wasting is associated with increased risk of mortality among women with pulmonary tuberculosis in urban Uganda[0]Harriet Mayanja-Kizza, [1]Ezekiel Mupere, [2]Lashaunda Malone, [3]Sarah Zalwango, [4]Allan Chiunda, [5]Alphonse Okwera, [6]Isabel Parraga, [7]Catherine M Stein, [8]Daniel J Tisch, [9]Roy Mugerwa, [10]W Henry Boom, [11]Harriet Mayanja, [12]Christopher C Whalen [Full author list]Annals of Epidemiology [curation]DOI: 10.1016/J.ANNEPIDEM.2012.04.007 [ORCID]
PubMed: 22575813 [ORCID]
Uganda [curation]; tuberculosis [curation]; urbanization [curation]; pulmonary tuberculosis [curation]2012-05-09
Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing[1]Daimon P Simmons, [2]Pamela A. Wearsch, [3]David H Canaday, [4]Howard J Meyerson, [5]Yi C Liu, [6]Ying Wang, [7]W Henry Boom, [8]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1101313 [ORCID]
PubMed: 22371391 [ORCID]
dendritic cell [curation]2012-02-27
CD8+ T cells provide an immunologic signature of tuberculosis in young children[1]Christina Lancioni, [2]Melissa Nyendak, [3]Sarah Kiguli, [4]Sarah Zalwango, [5]Tomi Mori, [6]Harriet Mayanja-Kizza, [7]Stephen Balyejusa, [8]Megan Null, [9]Joy Baseke, [10]Deo Mulindwa, [11]Laura Byrd, [12]Gwendolyn Swarbrick, [13]Christine Scott, [14]Denise F Johnson, [15]LaShaunda Malone, [16]Philipa Mudido-Musoke, [17]W Henry Boom, [18]David M. Lewinsohn, [19]Deborah A Lewinsohn [Full author list]American Journal of Respiratory and Critical Care Medicine [curation]DOI: 10.1164/RCCM.201107-1355OC [ORCID]
PubMed: 22071329 [ORCID]
tuberculosis [curation]2012-01-15
TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.[1]Yi C Liu, [2]Daimon P Simmons, [3]Xiaoxia Li, [4]Derek W. Abbott, [5]W Henry Boom, [6]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1102181 [ORCID]
PubMed: 22227568 [ORCID]
toll-like receptor [curation]2012-01-06
Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA-5.[1]Qing Li, [2]Xuedong Ding, [3]Jeremy J Thomas, [4]Clifford V Harding, [5]Nicole D Pecora, [6]Assem G Ziady, [7]Samuel Shank, [8]W Henry Boom, [9]Christina L Lancioni, [10]Roxana E Rojas [Full author list]Journal of Leukocyte Biology [curation]DOI: 10.1189/JLB.0711364 [ORCID]
PubMed: 22158781 [ORCID]
Mycobacterium tuberculosis [curation]2011-12-07
A novel metabolite of antituberculosis therapy demonstrates host activation of isoniazid and formation of the isoniazid-NAD+ adduct[1]Sebabrata Mahapatra, [2]Lisa K Woolhiser, [3]Anne J Lenaerts, [4]John L Johnson, [5]Kathleen D Eisenach, [6]Moses Joloba, [7]W Henry Boom, [8]John T Belisle [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.05486-11 [ORCID]
PubMed: 22037847 [ORCID]
isoniazid [curation]2011-10-28
CDC/NIH Workshop. Tuberculosis biomarker and surrogate endpoint research roadmap[1]Payam Nahid, [2]Jussi Saukkonen, [3]William R Mac Kenzie, [4]John L Johnson, [5]Patrick P J Phillips, [6]Janet Andersen, [7]Erin Bliven-Sizemore, [8]John T Belisle, [9]W Henry Boom, [10]Anne F. Luetkemeyer, [11]Thomas B Campbell, ... [Full author list]American Journal of Respiratory and Critical Care Medicine [curation]DOI: 10.1164/RCCM.201105-0827WS [ORCID]
PubMed: 21737585 [ORCID]
tuberculosis [curation]; biomarker [curation]; workshop [curation]2011-10-01
A randomized trial of punctuated antiretroviral therapy in Ugandan HIV-seropositive adults with pulmonary tuberculosis and CD4⁺ T-cell counts of ≥ 350 cells/μL.[1]M W Nanteza, [2]Harriet Mayanja-Kizza, [3]E Charlebois, [4]P Srikantiah, [5]R Lin, [6]E Mupere, [7]Peter Mugyenyi, [8]W H Boom, [9]R D Mugerwa, [10]D V Havlir, [11]C C Whalen [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/JIR503 [ORCID]
PubMed: 21849285 [ORCID]
Uganda [curation]; tuberculosis [curation]; pulmonary tuberculosis [curation]; anti-retroviral agent [curation]2011-09-01
Bacterial conversion of folinic acid is required for antifolate resistance[1]Sam Ogwang, [2]Hoa T Nguyen, [3]Marissa Sherman, [4]Saralee Bajaksouzian, [5]Michael R Jacobs, [6]W Henry Boom, [7]Guo-Fang Zhang, [8]Liem Nguyen [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M111.231076 [ORCID]
PubMed: 21372133 [ORCID]
2011-03-03
Time to detection of Mycobacterium tuberculosis as an alternative to quantitative cultures[1]C M Bark, [2]A Okwera, [3]Moses Joloba, [4]B A Thiel, [5]J G Nakibali, [6]S M Debanne, [7]W H Boom, [8]K D Eisenach, [9]J L Johnson [Full author list]Tuberculosis [curation]DOI: 10.1016/J.TUBE.2011.01.004 [ORCID]
PubMed: 21353641 [ORCID]
Mycobacterium tuberculosis [curation]2011-02-25
Secondary attack rate of tuberculosis in urban households in Kampala, Uganda[1]Christopher C Whalen, [2]Sarah Zalwango, [3]Allan Chiunda, [4]LaShaunda Malone, [5]Kathleen Eisenach, [6]Moses Joloba, [7]W Henry Boom, [8]Roy Mugerwa [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0016137 [ORCID]
PubMed: 21339819 [ORCID]
Uganda [curation]; tuberculosis [curation]2011-02-14
Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2.[1]Christina L Lancioni, [2]Qing Li, [3]Jeremy J Thomas, [4]XueDong Ding, [5]Bonnie Thiel, [6]Michael G Drage, [7]Nicole D Pecora, [8]Assem G Ziady, [9]Samuel Shank, [10]Clifford V Harding, [11]W Henry Boom, [12]Roxana E Rojas [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00806-10 [ORCID]
PubMed: 21078852 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2010-11-15
Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation[1]Lakshmi Ramachandra, [2]Yan Qu, [3]Ying Wang, [4]Colleen J Lewis, [5]Brian A Cobb, [6]Kiyoshi Takatsu, [7]W Henry Boom, [8]George R. Dubyak, [9]Clifford V Harding [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.01089-09 [ORCID]
PubMed: 20837713 [ORCID]
Mycobacterium tuberculosis [curation]2010-09-13
Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2[1]Michael G Drage, [2]Han-Chun Tsai, [3]Nicole D Pecora, [4]Tan-Yun Cheng, [5]Ahmad R Arida, [6]Supriya Shukla, [7]Roxana E Rojas, [8]Chetan Seshadri, [9]D. Branch Moody, [10]W Henry Boom, [11]James C Sacchettini, [12]Clifford V Harding [Full author list]Nature Structural & Molecular Biology [curation]DOI: 10.1038/NSMB.1869 [ORCID]
PubMed: 20694006 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; toll-like receptor [curation]; structural biology [curation]2010-09-01
Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9[1]Daimon P Simmons, [2]David H Canaday, [3]Yi Liu, [4]Qing Li, [5]Alex Y. Huang, [6]W Henry Boom, [7]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.0904005 [ORCID]
PubMed: 20660347 [ORCID]
Mycobacterium tuberculosis [curation]2010-07-21
Sputum Mycobacterium tuberculosis mRNA as a marker of bacteriologic clearance in response to antituberculosis therapy[1]L Li, [2]C S Mahan, [3]M Palaci, [4]L Horter, [5]L Loeffelholz, [6]J L Johnson, [7]R Dietze, [8]S M Debanne, [9]M L Joloba, [10]A Okwera, [11]W H Boom, [12]K D Eisenach [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.01526-09 [ORCID]
PubMed: 19923475 [ORCID]
tuberculosis [curation]; Mycobacterium tuberculosis [curation]; sputum [curation]2009-11-18
Population pharmacokinetics of linezolid in adults with pulmonary tuberculosis[1]Bryan McGee, [2]Reynaldo Dietze, [3]David Jamil Hadad, [4]Lucilia Pereira Dutra Molino, [5]Ethel Leonor Noia Maciel, [6]W Henry Boom, [7]Moises Palaci, [8]John L Johnson, [9]Charles A Peloquin [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.01378-08 [ORCID]
PubMed: 19564361 [ORCID]
tuberculosis [curation]; pharmacokinetics [curation]; linezolid [curation]2009-06-29
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa[1]Gillian F Black, [2]Bonnie A Thiel, [3]Martin O Ota, [4]Shreemanta Parida, [5]Richard Adebayo Adegbola, [6]W Henry Boom, [7]Hazel Dockrell, [8]Kees L M C Franken, [9]Annemiek H Friggen, [10]Philip C Hill, ... [Full author list]Clinical and Vaccine Immunology [curation]DOI: 10.1128/CVI.00111-09 [ORCID]
PubMed: 19553548 [ORCID]
Mycobacterium tuberculosis [curation]2009-06-24
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis[1]Michael G Drage, [2]Nicole D Pecora, [3]Amy G. Hise, [4]Maria Febbraio, [5]Roy L Silverstein, [6]Douglas T Golenbock, [7]W Henry Boom, [8]Clifford V Harding [Full author list]Cellular Immunology [curation]DOI: 10.1016/J.CELLIMM.2009.03.008 [ORCID]
PubMed: 19362712 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; macrophage [curation]; toll-like receptor [curation]; dendritic cell [curation]2009-04-11
CD4+ CD25(high) Foxp3+ regulatory T cells downregulate human Vdelta2+ T-lymphocyte function triggered by anti-CD3 or phosphoantigen[1]C Scott Mahan, [2]Jeremy J Thomas, [3]W Henry Boom, [4]Roxana E Rojas [Full author list]Immunology [curation]DOI: 10.1111/J.1365-2567.2008.02982.X [ORCID]
PubMed: 19019089 [ORCID]
2008-11-14
Whole blood interferon-gamma responses to mycobacterium tuberculosis antigens in young household contacts of persons with tuberculosis in Uganda[1]Deborah A Lewinsohn, [2]Sarah Zalwango, [3]Catherine M Stein, [4]Harriet Mayanja-Kizza, [5]Alphonse Okwera, [6]W Henry Boom, [7]Roy D Mugerwa, [8]Christopher C Whalen [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0003407 [ORCID]
PubMed: 18923705 [ORCID]
Uganda [curation]; tuberculosis [curation]; Mycobacterium tuberculosis [curation]; whole blood [curation]2008-10-15
Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis[1]Reynaldo Dietze, [2]David Jamil Hadad, [3]Bryan McGee, [4]Lucilia Pereira Dutra Molino, [5]Ethel Leonor Noia Maciel, [6]Charles A Peloquin, [7]Denise F Johnson, [8]Sara M Debanne, [9]Kathleen Eisenach, [10]W Henry Boom, [11]Moises Palaci, [12]John L Johnson [Full author list]American Journal of Respiratory and Critical Care Medicine [curation]DOI: 10.1164/RCCM.200806-892OC [ORCID]
PubMed: 18787216 [ORCID]
tuberculosis [curation]; linezolid [curation]; pulmonary tuberculosis [curation]2008-09-11
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection[1]Nicole D Pecora, [2]Scott A Fulton, [3]Scott M Reba, [4]Michael G Drage, [5]Daimon P Simmons, [6]Nancy J Urankar-Nagy, [7]W Henry Boom, [8]Clifford V Harding [Full author list]Cellular Immunology [curation]DOI: 10.1016/J.CELLIMM.2008.07.002 [ORCID]
PubMed: 18762288 [ORCID]
aerosol [curation]; Mycobacterium bovis [curation]; macrophage [curation]; dendritic cell [curation]2008-08-30
Class II MHC antigen processing in phagosomes[1]Lakshmi Ramachandra, [2]W Henry Boom, [3]Clifford V Harding [Full author list]Methods in Molecular Biology [curation]DOI: 10.1007/978-1-59745-157-4_23 [ORCID]
PubMed: 18425462 [ORCID]
2008-01-01
Population pharmacokinetics of levofloxacin, gatifloxacin, and moxifloxacin in adults with pulmonary tuberculosis[1]Charles A Peloquin, [2]David Jamil Hadad, [3]Lucilia Pereira Dutra Molino, [4]Moises Palaci, [5]W Henry Boom, [6]Reynaldo Dietze, [7]John L Johnson [Full author list]Antimicrobial Agents and Chemotherapy [curation]DOI: 10.1128/AAC.01036-07 [ORCID]
PubMed: 18070980 [ORCID]
tuberculosis [curation]; pharmacokinetics [curation]; levofloxacin [curation]; moxifloxacin [curation]2007-12-10
CCAAT/enhancer-binding protein beta and delta binding to CIITA promoters is associated with the inhibition of CIITA expression in response to Mycobacterium tuberculosis 19-kDa lipoprotein[1]Meghan E Pennini, [2]Yi Liu, [3]Jianqi Yang, [4]Colleen M Croniger, [5]W Henry Boom, [6]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.179.10.6910 [ORCID]
PubMed: 17982082 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]2007-11-01
Cavitary disease and quantitative sputum bacillary load in cases of pulmonary tuberculosis[1]Moises Palaci, [2]Reynaldo Dietze, [3]David Jamil Hadad, [4]Fabiola Karla Corrêa Ribeiro, [5]Renata Lyrio Peres, [6]Solange Alves Vinhas, [7]Ethel Leonor Noia Maciel, [8]Valdério do Valle Dettoni, [9]Libby Horter, [10]W Henry Boom, [11]John L Johnson, [12]Kathleen D Eisenach [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.01780-07 [ORCID]
PubMed: 17928422 [ORCID]
tuberculosis [curation]; sputum [curation]; pulmonary tuberculosis [curation]2007-10-10
Elevated HIV seroprevalence and risk behavior among Ugandan TB suspects: implications for HIV testing and prevention[1]P Srikantiah, [2]R Lin, [3]M Walusimbi, [4]A Okwera, [5]H Luzze, [6]C C Whalen, [7]W H Boom, [8]D V Havlir, [9]E D Charlebois [Full author list]International Journal of Tuberculosis and Lung Disease [curation]PubMed: 17263287 [ORCID]
Uganda [curation]; seroprevalence [curation]; prevention of HIV/AIDS [curation]2007-02-01
Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma[1]Ana Paula Junqueira-Kipnis, [2]Randall J Basaraba, [3]Veronica Gruppo, [4]Gopinath Palanisamy, [5]Oliver C Turner, [6]Tsungda Hsu, [7]William Jacobs, [8]Scott A Fulton, [9]Scott M Reba, [10]W Henry Boom, [11]Ian Orme [Full author list]Immunology [curation]DOI: 10.1111/J.1365-2567.2006.02427.X [ORCID]
PubMed: 17005003 [ORCID]
2006-10-01
Immune correlates of acute Mycobacterium tuberculosis infection in household contacts in Kampala, Uganda[1]Christopher C Whalen, [2]Allan Chiunda, [3]Sarah Zalwango, [4]Lorna Nshuti, [5]Edward Jones-Lopez, [6]Alphonse Okwera, [7]Christina Hirsch, [8]Pierre Peters, [9]W Henry Boom, [10]Roy D Mugerwa [Full author list]American Journal of Tropical Medicine and Hygiene [curation]PubMed: 16837709 [ORCID]
Uganda [curation]; Mycobacterium tuberculosis [curation]2006-07-01
Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function[1]Nicole D. Pecora, [2]Adam J. Gehring, [3]David H. Canaday, [4]W. Henry Boom, [5]Clifford V. Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.177.1.422 [ORCID]
PubMed: 16785538 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2006-07-01
Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis[1]J L Johnson, [2]D J Hadad, [3]W H Boom, [4]C L Daley, [5]C A Peloquin, [6]K D Eisenach, [7]D D Jankus, [8]S M Debanne, [9]E D Charlebois, [10]E Maciel, [11]M Palaci, [12]R Dietze [Full author list]International Journal of Tuberculosis and Lung Disease [curation]PubMed: 16776446 [ORCID]
tuberculosis [curation]; levofloxacin [curation]; moxifloxacin [curation]; pulmonary tuberculosis [curation]2006-06-01
Mycobacterium tuberculosis 19-kDa lipoprotein inhibits IFN-gamma-induced chromatin remodeling of MHC2TA by TLR2 and MAPK signaling[1]Meghan E Pennini, [2]Rish K Pai, [3]David C Schultz, [4]W Henry Boom, [5]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.176.7.4323 [ORCID]
PubMed: 16547269 [ORCID]
Mycobacterium tuberculosis [curation]; toll-like receptor [curation]2006-04-01
A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis[1]R Ribeiro-Rodrigues, [2]T Resende Co, [3]R Rojas, [4]Z Toossi, [5]R Dietze, [6]W H Boom, [7]Ethel Leonor Noia Maciel, [8]C S Hirsch [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1111/J.1365-2249.2006.03027.X [ORCID]
PubMed: 16542361 [ORCID]
tuberculosis [curation]2006-04-01
Phagosomal Processing of Antigen 85B Is Modulated Independently of Mycobacterial Viability and Phagosome Maturation[1]Lakshmi Ramachandra, [2]Jamie L. Smialek, [3]Sam S. Shank, [4]Marilyn Convery, [5]W. Henry Boom, [6]Clifford V. Harding [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.74.1.802.2006 [ORCID]
2006-01-01
Inhibition of IFN-gamma-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion[1]Rish K Pai, [2]Marilyn Convery, [3]Thomas A Hamilton, [4]W Henry Boom, [5]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.171.1.175 [ORCID]
PubMed: 12816996 [ORCID]
Mycobacterium tuberculosis [curation]; evasion of host immune response [curation]2003-07-01
Human immunity to M. tuberculosis: T cell subsets and antigen processing[1]W H Boom, [2]David H Canaday, [3]Scott A Fulton, [4]Adam J Gehring, [5]Roxana E Rojas, [6]Marta Torres [Full author list]Tuberculosis [curation]DOI: 10.1016/S1472-9792(02)00054-9 [ORCID]
PubMed: 12758197 [ORCID]
tuberculosis [curation]; Mycobacterium tuberculosis [curation]2003-01-01
ATP and control of intracellular growth of mycobacteria by T cells[1]David H Canaday, [2]Reza Beigi, [3]Richard F Silver, [4]Clifford V Harding, [5]W Henry Boom, [6]George R Dubyak [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.70.11.6456-6459.2002 [ORCID]
PubMed: 12379727 [ORCID]
2002-11-01
Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice[1]S A Fulton, [2]S M Reba, [3]T D Martin, [4]W H Boom [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.70.9.5322-5327.2002 [ORCID]
PubMed: 12183593 [ORCID]
Mycobacterium bovis [curation]2002-09-01
Regulation of class II MHC expression in APCs: roles of types I, III, and IV class II transactivator[1]Rish K Pai, [2]David Askew, [3]W Henry Boom, [4]Clifford V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.169.3.1326 [ORCID]
PubMed: 12133955 [ORCID]
2002-08-01
Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance[1]Rodrigo Ribeiro-Rodrigues, [2]Tatiana Resende Co, [3]John L Johnson, [4]Fabiola Ribeiro, [5]Moises Palaci, [6]Ricardo T Sá, [7]Ethel Leonor Noia Maciel, [8]Fausto E Pereira Lima, [9]Valderio Dettoni, [10]Zahra Toossi, [11]W Henry Boom, [12]Reynaldo Dietze, [13]Jerrold J Ellner, [14]Christina S Hirsch [Full author list]Clinical and Vaccine Immunology [curation]DOI: 10.1128/CDLI.9.4.818-823.2002 [ORCID]
PubMed: 12093679 [ORCID]
tuberculosis [curation]; sputum [curation]; pulmonary tuberculosis [curation]2002-07-01
Processing of Mycobacterium tuberculosis antigen 85B involves intraphagosomal formation of peptide-major histocompatibility complex II complexes and is inhibited by live bacilli that decrease phagosome maturation[1]L Ramachandra, [2]E Noss, [3]W H Boom, [4]C V Harding [Full author list]Journal of Experimental Medicine [curation]DOI: 10.1084/JEM.194.10.1421 [ORCID]
PubMed: 11714749 [ORCID]
Mycobacterium tuberculosis [curation]2001-11-01
Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis[1]E H Noss, [2]R K Pai, [3]T J Sellati, [4]J D Radolf, [5]J Belisle, [6]D T Golenbock, [7]W H Boom, [8]C V Harding [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.167.2.910 [ORCID]
PubMed: 11441098 [ORCID]
lipoprotein [curation]; Mycobacterium tuberculosis [curation]; macrophage [curation]; toll-like receptor [curation]2001-07-01
Human natural killer cells mediate killing of intracellular Mycobacterium tuberculosis H37Rv via granule-independent mechanisms[1]K J Brill, [2]Q Li, [3]R Larkin, [4]D H Canaday, [5]D R Kaplan, [6]W H Boom, [7]R F Silver [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.3.1755-1765.2001 [ORCID]
PubMed: 11179353 [ORCID]
Mycobacterium tuberculosis [curation]2001-03-01
Serum interleukin-6 (IL-6), IL-10, tumor necrosis factor (TNF) alpha, soluble type II TNF receptor, and transforming growth factor beta levels in human immunodeficiency virus type 1-infected individuals with Mycobacterium avium complex disease[1]D V Havlir, [2]F J Torriani, [3]R D Schrier, [4]J Y Huang, [5]M M Lederman, [6]K A Chervenak, [7]W H Boom [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.39.1.298-303.2001 [ORCID]
PubMed: 11136787 [ORCID]
Mycobacterium avium avium [curation]; TNF [curation]2001-01-01
Latency-associated peptide of transforming growth factor beta enhances mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice[1]K A Wilkinson, [2]T D Martin, [3]S M Reba, [4]H Aung, [5]R W Redline, [6]W H Boom, [7]Z Toossi, [8]S A Fulton [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.68.11.6505-6508.2000 [ORCID]
PubMed: 11035768 [ORCID]
Mycobacterium bovis [curation]2000-11-01
Regulation of human CD4(+) alphabeta T-cell-receptor-positive (TCR(+)) and gammadelta TCR(+) T-cell responses to Mycobacterium tuberculosis by interleukin-10 and transforming growth factor beta[1]R E Rojas, [2]K N Balaji, [3]A Subramanian, [4]W H Boom [Full author list]Infection and Immunity [curation]PubMed: 10569764 [ORCID]
Mycobacterium tuberculosis [curation]1999-12-01
Regulation of interleukin-12 by interleukin-10, transforming growth factor-beta, tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra[1]S A Fulton, [2]J V Cross, [3]Z T Toossi, [4]W H Boom [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1086/515698 [ORCID]
PubMed: 9806041 [ORCID]
Mycobacterium tuberculosis [curation]1998-10-01
Differing susceptibilities of mice, guinea pigs and rabbits to Mycobacterium tuberculosis[1]W H Boom, [2]Z Toossi [Full author list]Trends in Microbiology [curation]DOI: 10.1016/S0966-842X(98)01260-8 [ORCID]
PubMed: 9614341 [ORCID]
Mycobacterium tuberculosis [curation]1998-05-01
Processing of Mycobacterium tuberculosis bacilli by human monocytes for CD4+ alphabeta and gammadelta T cells: role of particulate antigen[1]K N Balaji, [2]W H Boom [Full author list]Infection and Immunity [curation]PubMed: 9423845 [ORCID]
Mycobacterium tuberculosis [curation]1998-01-01
Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression[1]A H Patki, [2]M E Quiñones-Mateu, [3]D Dorazio, [4]B Yen-Lieberman, [5]W H Boom, [6]E K Thomas, [7]M M Lederman [Full author list]Journal of Clinical Investigation [curation]DOI: 10.1172/JCI118831 [ORCID]
PubMed: 8698851 [ORCID]
interleukins [curation]; lymphocyte [curation]1996-08-01
Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis[1]S A Fulton, [2]J M Johnsen, [3]S F Wolf, [4]D S Sieburth, [4-Q110876452]Derek Sieburth, [5]W H Boom [Full author list]Infection and Immunity [curation]PubMed: 8698475 [ORCID]
Mycobacterium tuberculosis [curation]; phagocytosis [curation]1996-07-01
Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis[1]L Averill, [2]Z Toossi, [3]H Aung, [4]W H Boom, [5]J J Ellner [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.63.8.3206-3208.1995 [ORCID]
PubMed: 7622249 [ORCID]
Mycobacterium tuberculosis [curation]1995-08-01
Characterization of a 10- to 14-kilodalton protease-sensitive Mycobacterium tuberculosis H37Ra antigen that stimulates human gamma delta T cells[1]W H Boom, [2]K N Balaji, [3]R Nayak, [4]K Tsukaguchi, [5]K A Chervenak [Full author list]Infection and Immunity [curation]PubMed: 7960133 [ORCID]
Mycobacterium tuberculosis [curation]1994-12-01
Screening of a cosmid library of Mycobacterium bovis BCG in Mycobacterium smegmatis for novel T-cell stimulatory antigens[1]L E Averill, [2]U Cavallo, [3]R S Wallis, [4]W H Boom, [5]M Bona, [6]M Mincek, [7]L Pascopella, [8]William Jacobs, [9]Jerrold Ellner [Full author list]Research in Microbiology [curation]DOI: 10.1016/0923-2508(93)90192-5 [ORCID]
PubMed: 8248628 [ORCID]
Mycobacterium bovis [curation]; Mycobacterium smegmatis [curation]1993-06-01
Induction of murine T-helper-cell responses to the filarial nematode Brugia malayi[1]E Pearlman, [2]F E Hazlett, [3]W H Boom, [4]J W Kazura [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.61.3.1105-1112.1993 [ORCID]
PubMed: 8094378 [ORCID]
Brugia malayi [curation]1993-03-01
Brugia malayi: acquired resistance to microfilariae in BALB/c mice correlates with local Th2 responses.[1]E Pearlman, [2]W K Kroeze, [3]F E Hazlett, [4]S S Chen, [5]S D Mawhorter, [6]W H Boom, [7]J W Kazura [Full author list]Experimental Parasitology [curation]DOI: 10.1006/EXPR.1993.1023 [ORCID]
PubMed: 8454029 [ORCID]
Brugia malayi [curation]1993-03-01
Role of the mononuclear phagocyte as an antigen-presenting cell for human gamma delta T cells activated by live Mycobacterium tuberculosis[1]W. H. Boom, [2]K. A. Chervenak, [3]M. A. Mincek, [4]J. J. Ellner [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.60.9.3480-3488.1992 [ORCID]
PubMed: 1379984 [ORCID]
Mycobacterium tuberculosis [curation]; lymphocyte activation [curation]1992-09-01
Human Mycobacterium tuberculosis-reactive CD4+ T-cell clones: heterogeneity in antigen recognition, cytokine production, and cytotoxicity for mononuclear phagocytes[1]W. H. Boom, [2]Robert S Wallis, [3]K. A. Chervenak [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.59.8.2737-2743.1991 [ORCID]
PubMed: 1713198 [ORCID]
microbiology [curation]; immunology [curation]; Mycobacterium tuberculosis [curation]; cytotoxicity [curation]; immunologic cytotoxicity [curation]1991-08-01
Human immune response to Mycobacterium tuberculosis antigens[1]D V Havlir, [2]R S Wallis, [3]W H Boom, [4]T M Daniel, [5]K Chervenak, [6]J J Ellner [Full author list]Infection and Immunity [curation]PubMed: 1898911 [ORCID]
Mycobacterium tuberculosis [curation]1991-02-01
Patterns of cytokine secretion in murine leishmaniasis: correlation with disease progression or resolution[1]W H Boom, [2]L Liebster, [3]A K Abbas, [4]R G Titus [Full author list]Infection and Immunity [curation]PubMed: 2123823 [ORCID]
1990-12-01
Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4- and interleukin 2-producing T cell clones on resting B lymphocytes[1]W H Boom, [2]D Liano, [3]A K Abbas [Full author list]Journal of Experimental Medicine [curation]DOI: 10.1084/JEM.167.4.1350 [ORCID]
PubMed: 2965736 [ORCID]
interleukins [curation]; lymphocyte [curation]1988-04-01
In vivo and in vitro characterization of murine T-cell clones reactive to Mycobacterium tuberculosis[1]W H Boom, [2]R N Husson, [3]R A Young, [4]J R David, [5]W F Piessens [Full author list]Infection and Immunity [curation]PubMed: 3114149 [ORCID]
Mycobacterium tuberculosis [curation]1987-09-01

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W Henry Boomresearcher16ORCID: 0000-0001-5760-9595
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