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Jan Holmgren

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Listed Publications

364 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-β1 as strongly upregulated molecules involved in adjuvant activity[1]Manuela Terrinoni, [2]Jan Holmgren, [3]Michael Lebens, [4]Maximilian Larena [Full author list]Scientific Reports [curation]DOI: 10.1038/S41598-019-38726-0
PubMed: 30808871
cholera [curation]2019-02-26
Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NFκB Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT[1]Manuela Terrinoni, [2]Jan Holmgren, [3]Michael Lebens, [4]Maximilian Larena [Full author list]Frontiers in Immunology [curation]DOI: 10.3389/FIMMU.2019.00269
PubMed: 30838003
cholera [curation]; cholera toxin [curation]; MMCT [curation]; Mucosal Adjuvants [curation]2019-01-01
A novel non-antibiotic, lgt-based selection system for stable maintenance of expression vectors in Escherichia coli and Vibrio cholerae[1]Manuela Terrinoni, [2]Stefan Karlsson, [3]Susanne Källgård, [4]Jan Holmgren, [5]Michael Lebens [Full author list]Applied and Environmental Microbiology [curation]DOI: 10.1128/AEM.02143-17
PubMed: 29222103
Escherichia coli [curation]; Vibrio cholerae [curation]2017-12-08
Thermostability of the coating, antigen and immunostimulator in an adjuvanted oral capsule vaccine formulation[1]Stephanie Longet, [2]Vincenzo Aversa, [3]Daire O'Donnell, [4]Joshua Tobias, [5]Monica Rosa, [6]Jan Holmgren, [7]Ivan S Coulter, [8]Ed C Lavelle [Full author list]International Journal of Pharmaceutics [curation]DOI: 10.1016/J.IJPHARM.2017.10.013
PubMed: 29024788
2017-10-09
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin[1]Jia-Bin Sun, [2]Jan Holmgren, [3]Maximilian Larena, [4]Manuela Terrinoni, [5]Yu Fang, [6]Anne R Bresnick, [7]Zou Xiang [Full author list]Frontiers in Immunology [curation]DOI: 10.3389/FIMMU.2017.01119
PubMed: 28951732
cholera [curation]2017-09-11
Correlates of protection for enteric vaccines[1]Jan Holmgren, [2]Umesh Parashar, [3]Stanley Plotkin, [4]Jacques Louis, [5]Su-Peing Ng, [6]Eric Desauziers, [7]Valentina Picot, [8]Mitra Saadatian-Elahi [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2017.05.005
PubMed: 28504192
2017-05-11
Cholera.[1]John Clemens, [2]G Balakrish Nair, [3]Tahmeed Ahmed, [4]Firdausi Qadri, [5]Jan Holmgren [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(17)30559-7
PubMed: 28302312
cholera [curation]2017-03-10
Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens[1]Joshua Tobias, [2]Michael Lebens, [3]Sun Nyunt Wai, [4]Jan Holmgren, [5]Ann-Mari Svennerholm [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/J.MICPATH.2017.02.021
PubMed: 28215587
Escherichia coli [curation]; Vibrio cholerae [curation]; Helicobacter pylori [curation]; enterotoxigenic Escherichia coli [curation]2017-02-16
Lack of Fc Gamma Receptor IIIA Promotes Rather than Suppresses Humoral and Cellular Immune Responses after Mucosal or Parenteral Immunization with Antigen and Adjuvants[1]J-B Sun, [2]Jan Holmgren, [3]M S Cragg, [4]Z Xiang [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/SJI.12528
PubMed: 28128471
2017-01-27
Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process[1]Stefan L Karlsson, [2]Nicholas Thomson, [3]Ankur Mutreja, [4]Thomas R. Connor, [5]Dipika Sur, [6]Mohammad Ali, [7]John Clemens, [8]Gordon Dougan, [9]Jan Holmgren, [10]Michael Lebens [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0005044
PubMed: 27706170
cholera [curation]; Vibrio cholerae [curation]2016-10-05
Preparation and preclinical evaluation of a freeze-dried formulation of a novel combined multivalent whole-cell/B-subunit oral vaccine against enterotoxigenic Escherichia coli diarrhea[1]Annika Borde, [2]Annelie Ekman, [3]Anette Larsson, [4]Nils Carlin, [5]Jan Holmgren, [6]Joshua Tobias [Full author list]European Journal of Pharmaceutics and Biopharmaceutics [curation]DOI: 10.1016/J.EJPB.2016.07.011
PubMed: 27485398
Escherichia coli [curation]; diarrhea [curation]; enterotoxigenic Escherichia coli [curation]; freeze-drying [curation]2016-07-30
Vaccines against enteric infections for the developing world[1]Cecil Czerkinsky, [2]Jan Holmgren [Full author list]Philosophical Transactions of the Royal Society B [curation]DOI: 10.1098/RSTB.2015.0142
PubMed: 25964464
2015-06-19
Development of stable Vibrio cholerae O1 Hikojima type vaccine strains co-expressing the Inaba and Ogawa lipopolysaccharide antigens[1]Stefan Karlsson, [2]Elisabeth Ax, [3]Erik Nygren, [4]Susanne Källgård, [5]Margareta Blomquist, [6]Annelie Ekman, [7]John Benktander, [8]Jan Holmgren, [9]Michael Lebens [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0108521
PubMed: 25397871
Vibrio cholerae [curation]; lipopolysaccharide [curation]2014-11-14
Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study[1]Anna Lundgren, [2]Louis Bourgeois, [3]Nils Carlin, [4]John Clements, [5]Björn Gustafsson, [6]Marianne Hartford, [7]Jan Holmgren, [8]Max Petzold, [9]Richard Walker, [10]Ann-Mari Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2014.10.069
PubMed: 25444830
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]; placebo [curation]2014-11-05
Vibriocidal antibody responses to a bivalent killed whole-cell oral cholera vaccine in a phase III trial in Kolkata, India[1]Suman Kanungo, [2]Anna Lena Lopez, [3]Mohammad Ali, [4]Byomkesh Manna, [5]Deok Ryon Kim, [6]Tanmay Mahapatra, [7]Jan Holmgren, [8]Mandeep S Dhingra, [9]Thomas F Weirzba, [10]G Balakrish Nair, [11]Sujit K Bhattacharya, [12]John Clemens, [13]Dipika Sur [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0096499
PubMed: 24800828
India [curation]; cholera [curation]; phase III clinical trial [curation]2014-05-06
When, how, and where can oral cholera vaccines be used to interrupt cholera outbreaks?[1]John Clemens, [2]Jan Holmgren [Full author list]Current Topics in Microbiology and Immunology [curation]DOI: 10.1007/82_2013_353
PubMed: 24402712
cholera [curation]2014-01-01
Natural evolution and human consciousness[1]Jan Holmgren [Full author list]Mens Sana Monographs [curation]DOI: 10.4103/0973-1229.130322
PubMed: 24891802
consciousness [curation]2014-01-01
Cholera toxin expression by El Tor Vibrio cholerae in shallow culture growth conditions[1]Mayra Cobaxin, [2]Haydee Martínez, [3]Guadalupe Ayala, [4]Jan Holmgren, [5]Åsa Sjöling, [6]Joaquín Sánchez [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/J.MICPATH.2013.11.002
PubMed: 24239941
cholera [curation]; Vibrio cholerae [curation]2013-11-14
5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: a cluster-randomised, double-blind, placebo-controlled trial.[1]Sujit K Bhattacharya, [2]Dipika Sur, [3]Mohammad Ali, [4]Suman Kanungo, [5]Young Ae You, [6]Byomkesh Manna, [7]Binod Sah, [8]Swapan K Niyogi, [9]Jin Kyung Park, [10]Banawarilal Sarkar, ..., [12]Deok Ryun Kim, [13]Jacqueline L Deen, [14]Jan Holmgren, [15]Rodney Carbis, [16]Mandeep Singh Dhingra, ... [Full author list]Lancet Infectious Diseases [curation]DOI: 10.1016/S1473-3099(13)70273-1
PubMed: 24140390
India [curation]; cholera [curation]; vaccine [curation]; placebo [curation]2013-10-18
Important role for FcγRIIB on B lymphocytes for mucosal antigen-induced tolerance and Foxp3+ regulatory T cells[1]Jia-Bin Sun, [2]Zou Xiang, [3]Kenneth G C Smith, [4]Jan Holmgren [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.1301324
PubMed: 24038083
2013-09-13
Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administe[1]Jan Holmgren, [2]L Bourgeois, [3]N Carlin, [4]J Clements, [5]B Gustafsson, [6]A Lundgren, [7]E Nygren, [8]J Tobias, [9]R Walker, [10]A-M Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2013.03.027
PubMed: 23541621
Escherichia coli [curation]; vaccine [curation]; overexpression [curation]2013-03-27
A double mutant heat-labile toxin from Escherichia coli, LT(R192G/L211A), is an effective mucosal adjuvant for vaccination against Helicobacter pylori infection[1]Louise Sjökvist Ottsjö, [2]Carl-Fredrik Flach, [3]John Clements, [4]Jan Holmgren, [5]Sukanya Raghavan [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.01407-12
PubMed: 23439305
Escherichia coli [curation]; immunology [curation]; parasitology [curation]; Helicobacter pylori [curation]; Helicobacter pylori infectious disease [curation]; infectious disease [curation]2013-02-25
Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein[1]A Lundgren, [2]S Leach, [3]J Tobias, [4]N Carlin, [5]B Gustafsson, [6]M Jertborn, [7]L Bourgeois, [8]R Walker, [9]Jan Holmgren, [10]A-M Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2012.12.063
PubMed: 23306362
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]; overexpression [curation]2013-01-07
Anti-bacterial and anti-toxic immunity induced by a killed whole-cell-cholera toxin B subunit cholera vaccine is essential for protection against lethal bacterial infection in mouse pulmonary cholera model[1]S-S Kang, [2]J S Yang, [3]K W Kim, [4]C-H Yun, [5]Jan Holmgren, [6]C Czerkinsky, [7]S H Han [Full author list]Mucosal Immunology [curation]DOI: 10.1038/MI.2012.121
PubMed: 23187318
cholera [curation]2012-11-28
Vaccines against mucosal infections[1]Jan Holmgren, [2]Ann-Mari Svennerholm [Full author list]Current Opinion in Immunology [curation]DOI: 10.1016/J.COI.2012.03.014
PubMed: 22580196
2012-05-12
Migration routes and strategies in a highly aerial migrant, the common swift Apus apus, revealed by light-level geolocators[1]Susanne Åkesson, [2]Raymond H G Klaassen, [3]Jan Holmgren, [4]James W Fox, [5]Anders Hedenström [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0041195
PubMed: 22815968
Common Swift [curation]2012-01-01
Mucosal delivery routes for optimal immunization: targeting immunity to the right tissues[1]C Czerkinsky, [2]Jan Holmgren [Full author list]Current Topics in Microbiology and Immunology [curation]DOI: 10.1007/82_2010_112
PubMed: 21053117
immunization [curation]2012-01-01
New-generation vaccines against cholera[1]John Clemens, [2]Sunheang Shin, [3]Dipika Sur, [4]G Balakrish Nair, [5]Jan Holmgren [Full author list]Nature Reviews Gastroenterology & Hepatology [curation]DOI: 10.1038/NRGASTRO.2011.174
PubMed: 22064524
cholera [curation]2011-11-08
Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial[1]Dipika Sur, [2]Suman Kanungo, [3]Binod Sah, [4]Byomkesh Manna, [5]Mohammad Ali, [6]Allison M Paisley, [7]Swapan K Niyogi, [8]Jin Kyung Park, [9]Banawarilal Sarkar, [10]Mahesh C Puri, [11]Deok Ryun Kim, [12]Jacqueline L Deen, [13]Jan Holmgren, [14]Rodney Carbis, [15]Raman Rao, ... [Full author list]PLoS Neglected Tropical Diseases [curation]DOI: 10.1371/JOURNAL.PNTD.0001289
PubMed: 22028938
cholera [curation]; cholera vaccine [curation]2011-10-18
Construction of a non-toxigenic Escherichia coli oral vaccine strain expressing large amounts of CS6 and inducing strong intestinal and serum anti-CS6 antibody responses in mice[1]Joshua Tobias, [2]Ann-Mari Svennerholm, [3]Nils I A Carlin, [4]Michael Lebens, [5]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2011.09.096
PubMed: 21983363
Escherichia coli [curation]; antibody [curation]2011-10-06
Evidence for several waves of global transmission in the seventh cholera pandemic[1]Ankur Mutreja, [2]Dong Wook Kim, [3]Nicholas Thomson, [4]Thomas R. Connor, [5]Je Hee Lee, [6]Samuel Kariuki, [7]Nicholas J Croucher, [8]Seon Young Choi, [9]Simon R Harris, [10]Michael Lebens, ..., [17]Cecil Czerkinsky, [18]G Balakrish Nair, [19]Jan Holmgren, [20]Julian Parkhill, [21]Gordon Dougan [Full author list]Nature [curation]DOI: 10.1038/NATURE10392
PubMed: 21866102
cholera [curation]; pandemic [curation]2011-08-24
The subcellular location of antigen expressed by adenoviral vectors modifies adaptive immunity but not dependency on cross-presenting dendritic cells[1]Petra Henning, [2]Tobias Gustafsson, [3]Carl-Fredrik Flach, [4]Yeu-Jiann Hua, [5]Anna Strömbeck, [6]Jan Holmgren, [7]Leif Lindholm, [8]Ulf Yrlid [Full author list]European Journal of Immunology [curation]DOI: 10.1002/EJI.201041009
PubMed: 21538977
Adenoviridae [curation]; dendritic cell [curation]2011-07-06
Impaired IFN-γ production after stimulation with bacterial components by natural killer cells from gastric cancer patients[1]Åsa Lindgren, [2]Cheol-Heui Yun, [3]Åsa Sjöling, [4]Camilla Berggren, [5]Jia-Bin Sun, [6]Erik Jonsson, [7]Jan Holmgren, [8]Ann-Mari Svennerholm, [9]Samuel B. Lundin [Full author list]Experimental Cell Research [curation]DOI: 10.1016/J.YEXCR.2011.01.006
PubMed: 21255568
2011-04-01
Cholera toxin - a foe & a friend[1]Joaquin Sanchez, [2]Jan Holmgren, [2-Q5811529]Jan Holmgren [Full author list]Indian Journal of Medical Research [curation]PubMed: 21415489enzyme [curation]; cholera [curation]2011-02-01
Sublingual vaccination[1]Cecil Czerkinsky, [2]Nicolas Cuburu, [3]Mi-Na Kweon, [4]Fabienne Anjuere, [5]Jan Holmgren [Full author list]Hum Vaccin [curation]DOI: 10.4161/HV.7.1.13739
PubMed: 21263223
2011-01-01
Ten years of the Global Alliance for Vaccines and Immunization: challenges and progress[1]John Clemens, [2]Jan Holmgren, [3]Stefan Kaufmann, [4]Alberto Mantovani [Full author list]Nature Immunology [curation]DOI: 10.1038/NI1210-1069
PubMed: 21079627
immunization [curation]2010-12-01
Sublingual immunization protects against Helicobacter pylori infection and induces T and B cell responses in the stomach[1]Sukanya Raghavan, [2]Anna Karin Ostberg, [3]Carl-Fredrik Flach, [4]Annelie Ekman, [5]Margareta Blomquist, [6]Cecil Czerkinsky, [7]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.00536-10
PubMed: 20696831
Helicobacter pylori [curation]; immunization [curation]; Helicobacter pylori infectious disease [curation]; infectious disease [curation]2010-10-01
Topical immunization strategies[1]C Czerkinsky, [2]Jan Holmgren [Full author list]Mucosal Immunology [curation]DOI: 10.1038/MI.2010.55
PubMed: 20861833
immunization [curation]2010-09-22
Over-expression of major colonization factors of enterotoxigenic Escherichia coli, alone or together, on non-toxigenic E. coli bacteria.[1]Joshua Tobias, [2]Jan Holmgren, [3]Maria Hellman, [4]Erik Nygren, [5]Michael Lebens, [6]Ann-Mari Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2010.08.047
PubMed: 20728524
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]2010-08-20
Construction and expression of immunogenic hybrid enterotoxigenic Escherichia coli CFA/I and CS2 colonization fimbriae for use in vaccines.[1]Joshua Tobias, [2]Ann-Mari Svennerholm, [3]Jan Holmgren, [4]Michael Lebens [Full author list]Applied Microbiology and Biotechnology [curation]DOI: 10.1007/S00253-010-2577-4
PubMed: 20405124
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]2010-04-20
Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit[1]J-B Sun, [2]C Czerkinsky, [3]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.2009.02321.X
PubMed: 20017804
cholera [curation]; immunologic adjuvant [curation]2010-01-01
Sublingual immunization with nonreplicating antigens induces antibody-forming cells and cytotoxic T cells in the female genital tract mucosa and protects against genital papillomavirus infection.[1]Nicolas Cuburu, [2]Mi-Na Kweon, [3]Catherine Hervouet, [4]Hye-Ran Cha, [5]Yuk-Ying S Pang, [6]Jan Holmgren, [7]Konrad Stadler, [8]John T Schiller, [9]Fabienne Anjuère, [10]Cecil Czerkinsky [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.0803740
PubMed: 19933861
antibody [curation]; cytotoxicity [curation]; immunization [curation]2009-12-01
Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial[1]Dipika Sur, [2]Anna Lena Lopez, [3]Suman Kanungo, [4]Allison M Paisley, [5]Byomkesh Manna, [6]Mohammad Ali, [7]Swapan K Niyogi, [8]Jin Kyung Park, [9]Banawarilal Sarkar, [10]Mahesh C Puri, [11]Deok Ryun Kim, [12]Jacqueline L Deen, [13]Jan Holmgren, [14]Rodney Carbis, [15]Raman Rao, ... [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(09)61297-6
PubMed: 19819004
India [curation]; cholera [curation]; vaccine [curation]; placebo [curation]2009-10-08
Vibrio cholerae O139 capsular polysaccharide confers complement resistance in the absence or presence of antibody yet presents a productive target for cell lysis: implications for detection of bactericidal antibodies[1]Stephen R Attridge, [2]Jan Holmgren [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/J.MICPATH.2009.09.013
PubMed: 19818394
polysaccharide [curation]; Vibrio cholerae [curation]2009-10-07
Induction of protective immunity by vaccination against Chlamydia trachomatis using the major outer membrane protein adjuvanted with CpG oligodeoxynucleotide coupled to the nontoxic B subunit of cholera toxin[1]Chunmei Cheng, [2]Ilham Bettahi, [3]Maria I Cruz-Fisher, [4]Sukumar Pal, [5]Pooja Jain, [6]Zhenyu Jia, [7]Jan Holmgren, [8]Ali M Harandi, [9]Luis M de la Maza [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2009.07.108
PubMed: 19686693
cholera [curation]; Chlamydia trachomatis [curation]; membrane protein [curation]2009-08-15
Enteric vaccines for the developing world: a challenge for mucosal immunology[1]C Czerkinsky, [2]Jan Holmgren [Full author list]Mucosal Immunology [curation]DOI: 10.1038/MI.2009.22
PubMed: 19421181
immunology [curation]2009-05-06
Public health. The cholera crisis in Africa[1]S Bhattacharya, [2]Robert E. Black, [3]L Bourgeois, [4]J Clemens, [5]A Cravioto, [6]J L Deen, [7]Gordon Dougan, [8]R Glass, [9]R F Grais, [10]M Greco, [11]I Gust, [12]Jan Holmgren, [13]Simon Kariuki, [14]P-H Lambert, ... [Full author list]Science [curation]DOI: 10.1126/SCIENCE.1173890
PubMed: 19443768
cholera [curation]; public health [curation]2009-05-01
Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other mucosal and systemic responses[1]Sohel Shamsuzzaman, [2]Tanvir Ahmed, [3]Kaiissar Mannoor, [4]Yasmin Ara Begum, [4-Q60255994]Yasmin Ara Begum, [5]Pradip Kumar Bardhan, [6]Bradley Sack, [7]David A Sack, [7-Q57934978]David A. Sack, [8]Ann-Mari Svennerholm, [9]Jan Holmgren, [10]Firdausi Qadri, [9-Q5811529]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2008.12.041
PubMed: 19146897
Bangladesh [curation]; cholera [curation]; antibody [curation]; vaccine [curation]; Vibrio cholerae [curation]; immunization [curation]2009-01-13
Phage display for site-specific immunization and characterization of high-risk human papillomavirus specific E7 monoclonal antibodies[1]Maria Lidqvist, [2]Olle Nilsson, [3]Jan Holmgren, [4]Christina Hall, [5]Christian Fermér [Full author list]Journal of Immunological Methods [curation]DOI: 10.1016/J.JIM.2008.06.002
PubMed: 18606164
phage display [curation]2008-07-09
Cholera toxin structure, gene regulation and pathophysiological and immunological aspects[1]J Sánchez, [2]Jan Holmgren [Full author list]Cellular and Molecular Life Sciences [curation]DOI: 10.1007/S00018-008-7496-5
PubMed: 18278577
cholera [curation]; pathophysiology [curation]2008-05-01
Suppression of HIV replication in vitro by CpG and CpG conjugated to the non toxic B subunit of cholera toxin.[1]Salma Nowroozalizadeh, [2]Marianne Jansson, [3]Jenni Adamsson, [4]Marianne Lindblad, [5]Eva-Maria Fenyö, [6]Jan Holmgren, [7]Ali M Harandi [Full author list]Current HIV Research [curation]DOI: 10.2174/157016208784325038
PubMed: 18473786
cholera [curation]2008-05-01
Reply on new drugs against type 2 diabetes: important to gain experience and knowledge[1]Ake Sjöholm, [2]Carl-David Agardh, [3]Kerstin Brismar, [4]Suad Efendic, [5]Björn Eliasson, [6]Jan W Eriksson, [7]Anders Frid, [8]Leif Groop, [9]Jan Holmgren, [10]Martin Ridderstråle, [11]Ulf Smith [Full author list]Läkartidningen [curation]PubMed: 185615352008-04-01
A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India[1]Dilip Mahalanabis, [2]Anna Lena Lopez, [3]Dipika Sur, [4]Jacqueline L Deen, [5]Byomkesh Manna, [6]Suman Kanungo, [7]Lorenz von Seidlein, [8]Rodney Carbis, [9]Seung Hyun Han, [10]Seong Hye Shin, [11]Stephen Attridge, [12]Raman Rao, [13]Jan Holmgren, [14]John Clemens, [15]Sujit K Bhattacharya [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0002323
PubMed: 18523643
India [curation]; cholera [curation]; vaccine [curation]; placebo [curation]; placebo-controlled trial [curation]2008-01-01
Vaccine Protection of Bangladeshi infants and young children against cholera: implications for vaccine deployment and person-to-person transmission.[1]Mohammad Ali, [2]Michael Emch, [3]Mohammad Yunus, [4]David A. Sack, [5]Anna Lena Lopez, [6]Jan Holmgren, [7]John Clemens [Full author list]Pediatric Infectious Disease Journal [curation]DOI: 10.1097/INF.0B013E318149DFFD
PubMed: 18162935
Bangladesh [curation]; cholera [curation]2008-01-01
Sublingual 'oral tolerance' induction with antigen conjugated to cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells.[1]Sun JB, [2]Czerkinsky C, [3]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.2007.01975.X
PubMed: 17635805
cholera [curation]2007-08-01
Differential expression of intestinal membrane transporters in cholera patients[1]Carl-Fredrik Flach, [2]Firdausi Qadri, [3]Taufiqur R Bhuiyan, [4]Nur H Alam, [5]Eva Jennische, [6]Jan Holmgren, [7]Ivar Lönnroth [Full author list]FEBS Letters [curation]DOI: 10.1016/J.FEBSLET.2007.06.001
PubMed: 17575980
cholera [curation]; patient [curation]; solute carrier family 6 member 4 [curation]; response to toxic substance [curation]; Transient receptor potential cation channel subfamily M member 6 [curation]; Aquaporin 10 [curation]; Solute carrier family 23 member 1 [curation]; Solute carrier family 7 member 11 [curation]; Solute carrier family 6 member 14 [curation]; Solute carrier family 30 member 4 [curation]2007-07-10
COMMENTARY[1]Jan Holmgren, [2]Lars-Åke Nilsson [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]DOI: 10.1111/J.1600-0463.2007.APM_738.X
2007-05-01
Broad up-regulation of innate defense factors during acute cholera[1]Carl-Fredrik Flach, [2]Firdausi Qadri, [3]Taufiqur R Bhuiyan, [4]Nur H Alam, [5]Eva Jennische, [6]Ivar Lönnroth, [7]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.01900-06
PubMed: 17307946
cholera [curation]2007-02-16
Oral tolerance induction with antigen conjugated to cholera toxin B subunit generates both Foxp3+CD25+ and Foxp3-CD25- CD4+ regulatory T cells[1]Jia-Bin Sun, [2]Sukanya Raghavan, [3]Asa Sjöling, [4]Samuel Lundin, [5]Jan Holmgren, [5-Q5811529]Jan Holmgren [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.177.11.7634
PubMed: 17114433
cholera [curation]2006-12-01
Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.[1]Duc Anh Dang, [2]Jiebin Zhang, [3]Anna Lena Lopez, [4]Vu Dinh Thiem, [5]Phan Thi Long, [6]Nguyen Hong Son, [7]Jacqueline Deen, [8]Lorenz von Seidlein, [9]Rodney Carbis, [10]Seung Hyun Han, [11]Seong Hye Shin, [12]Stephen Attridge, [13]Jan Holmgren, [14]John Clemens [Full author list]Vaccine [curation]DOI: 10.1016/J.VACCINE.2006.09.049
PubMed: 17055622
cholera [curation]; vaccine [curation]2006-09-29
Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh[1]G Balakrish Nair, [2]Firdausi Qadri, [3]Jan Holmgren, [4]Ann-Mari Svennerholm, [5]Ashrafus Safa, [6]Nurul A Bhuiyan, [7]Q Shafi Ahmad, [8]Shah M Faruque, [9]A S G Faruque, [10]Yoshifumi Takeda, [11]David A. Sack [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.01304-06
PubMed: 16957040
Bangladesh [curation]; cholera [curation]; Vibrio cholerae [curation]2006-09-06
Fracture strength of two oxide ceramic crown systems after cyclic pre-loading and thermocycling.[1]Vult von Steyern P, [2]Ebbesson S, [3]Jan Holmgren, [4]Haag P, [5]Nilner K [Full author list]Journal of Oral Rehabilitation [curation]DOI: 10.1111/J.1365-2842.2005.01604.X
PubMed: 16922742
bone fracture [curation]2006-09-01
Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers[1]Iain Stephenson, [2]Maria C Zambon, [3]Anna Rudin, [4]Anthony Colegate, [5]Audino Podda, [6]Roberto Bugarini, [7]Giusseppe Del Giudice, [8]Ada Minutello, [9]Susan Bonnington, [10]Jan Holmgren, [11]Kingston H G Mills, [11-Q45449153]Kingston H Mills, [12]Karl G Nicholson [Full author list]Journal of Virology [curation]DOI: 10.1128/JVI.80.10.4962-4970.2006
PubMed: 16641287
Escherichia coli [curation]; vaccine [curation]; influenza vaccine [curation]2006-05-01
Dendritic cell-mediated induction of mucosal cytotoxic responses following intravaginal immunization with the nontoxic B subunit of cholera toxin[1]Carmelo Luci, [2]Catherine Hervouet, [3]Déborah Rousseau, [4]Jan Holmgren, [5]Cecil Czerkinsky, [6]Fabienne Anjuère [Full author list]Journal of Immunology [curation]DOI: 10.4049/JIMMUNOL.176.5.2749
PubMed: 16493030
cholera [curation]; cytotoxicity [curation]; dendritic cell [curation]; immunization [curation]2006-03-01
Cholera Toxin Induces a Transient Depletion of CD8 Intraepithelial Lymphocytes in the Rat Small Intestine as Detected by Microarray and Immunohistochemistry[1]Carl-Fredrik Flach, [2]Stefan Lange, [3]Eva Jennische, [4]Ivar Lönnroth, [5]Jan Holmgren, [5-Q5811529]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.73.11.7788.2005
cholera [curation]; immunohistochemistry [curation]2005-11-01
CpG oligodeoxynucleotide augments HSV-2 glycoprotein D DNA vaccine efficacy to generate T helper 1 response and subsequent protection against primary genital herpes infection in mice[1]Sara Tengvall, [2]Agnetha Josefsson, [3]Jan Holmgren, [4]Ali M Harandi [Full author list]Journal of Reproductive Immunology [curation]DOI: 10.1016/J.JRI.2005.06.010
PubMed: 16229896
genital herpes [curation]; Human herpesvirus 2 [curation]2005-10-17
Cholera toxin induces a transient depletion of CD8+ intraepithelial lymphocytes in the rat small intestine as detected by microarray and immunohistochemistry[1]Carl-Fredrik Flach, [2]Stefan Lange, [3]Eva Jennische, [4]Ivar Lönnroth, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.73.9.5595-5602.2005
PubMed: 16113276
cholera [curation]; immunohistochemistry [curation]2005-09-01
Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea[1]Joaquín Sánchez, [2]Jan Holmgren [Full author list]Current Opinion in Immunology [curation]DOI: 10.1016/J.COI.2005.06.007
PubMed: 15963708
cholera [curation]; diarrhea [curation]; vaccine [curation]2005-08-01
Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis[1]Mohammad Ali, [2]Michael Emch, [3]Lorenz von Seidlein, [4]Mohammad Yunus, [5]David A. Sack, [6]Malla Rao, [7]Jan Holmgren, [8]John Clemens [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(05)66550-6
PubMed: 15993232
Bangladesh [curation]; cholera [curation]; herd immunity [curation]2005-07-01
CD4+CD25+ suppressor T cells regulate pathogen induced inflammation and disease[1]Sukanya Raghavan, [2]Jan Holmgren [Full author list]FEMS Immunology and Medical Microbiology [curation]DOI: 10.1016/J.FEMSIM.2004.10.017
PubMed: 15866205
2005-05-01
Mucosal immunity and vaccines[1]Jan Holmgren, [2]Cecil Czerkinsky [Full author list]Nature Medicine [curation]DOI: 10.1038/NM1213
PubMed: 15812489
2005-04-01
Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon production[1]Cheol H Yun, [2]Anna Lundgren, [3]Josef Azem, [4]Asa Sjöling, [5]Jan Holmgren, [6]Ann-Mari Svennerholm, [7]B Samuel Lundin [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.73.3.1482-1490.2005
PubMed: 15731046
Helicobacter pylori [curation]; Helicobacter pylori infectious disease [curation]2005-03-01
Vaccination with dendritic cells pulsed in vitro with tumor antigen conjugated to cholera toxin efficiently induces specific tumoricidal CD8+ cytotoxic lymphocytes dependent on cyclic AMP activation of dendritic cells[1]Sun JB, [2]Eriksson K, [3]Li BL, [4]Lindblad M, [5]Azem J, [6]Jan Holmgren [Full author list]Clinical Immunology [curation]DOI: 10.1016/J.CLIM.2004.03.001
PubMed: 15207780
cholera [curation]; cytotoxicity [curation]; dendritic cell [curation]2004-07-01
Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells[1]Raghavan S, [2]Suri-Payer E, [3]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.0300-9475.2004.01447.X
PubMed: 15238076
Helicobacter pylori [curation]2004-07-01
Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behcet's disease[1]Stanford M, [2]Whittall T, [3]Bergmeier LA, [4]Lindblad M, [5]Lundin S, [6]Shinnick T, [7]Mizushima Y, [8]Jan Holmgren, [9]Lehner T [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1111/J.1365-2249.2004.02520.X
PubMed: 15196263
cholera [curation]; uveitis [curation]; Behçet's disease [curation]2004-07-01
Current status and future prospects for a vaccine against schistosomiasis[1]Michael Lebens, [2]Jia-Bin Sun, [3]Cecil Czerkinsky, [4]Jan Holmgren [Full author list]Expert Review of Vaccines [curation]DOI: 10.1586/14760584.3.3.315
PubMed: 15176948
schistosomiasis [curation]2004-06-01
Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based method[1]John Clemens, [2]Stephen Savarino, [3]Remon Abu-Elyazeed, [4]Mohammad Safwat, [5]Malla Rao, [6]Thomas F Wierzba, [7]Ann-Marie Svennerholm, [8]Jan Holmgren, [9]Robert Frenck, [10]Eunsik Park, [11]Abdollah Naficy [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1086/386288
PubMed: 15181579
Egypt [curation]; Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]2004-05-25
Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor[1]Kristina Eriksson, [2]Jia-Bin Sun, [3]Inger Nordström, [4]Margareta Fredriksson, [5]Marianne Lindblad, [6]Bin-Ling Li, [7]Jan Holmgren [Full author list]European Journal of Immunology [curation]DOI: 10.1002/EJI.200324368
PubMed: 15114660
cholera [curation]; cytotoxicity [curation]; dendritic cell [curation]2004-05-01
Expression of cholera toxin under non-AKI conditions in Vibrio cholerae El Tor induced by increasing the exposed surface of cultures[1]Joaquín Sánchez, [2]Gerardo Medina, [3]Thomas Buhse, [4]Jan Holmgren, [5]Gloria Soberón-Chávez [Full author list]Journal of Bacteriology [curation]DOI: 10.1128/JB.186.5.1355-1361.2004
PubMed: 14973024
cholera [curation]; Vibrio cholerae [curation]2004-03-01
Orally Administered CpG Oligodeoxynucleotide Induces Production of CXC and CC Chemokines in the Gastric Mucosa and Suppresses Bacterial Colonization in a Mouse Model of Infection[1]S. Raghavan, [2]J. Nyström, [3]M. Fredriksson, [4]J. Holmgren, [4-Q5811529]Jan Holmgren, [5]A. M. Harandi [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.72.3.1842.2004
Helicobacter pylori [curation]2004-03-01
Intranasal immunization of mice with group B streptococcal protein rib and cholera toxin B subunit confers protection against lethal infection[1]Charlotte Larsson, [2]Jan Holmgren, [3]Gunnar Lindahl, [4]Charlotta Bergquist [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.72.2.1184-1187.2004
PubMed: 14742572
cholera [curation]2004-02-01
CpG DNA as a potent inducer of mucosal immunity: implications for immunoprophylaxis and immunotherapy of mucosal infections[1]Ali M Harandi, [2]Jan Holmgren [Full author list]Current Opinion in Investigational Drugs [curation]PubMed: 15043387immunotherapy [curation]2004-02-01
Orally administered CpG oligodeoxynucleotide induces production of CXC and CC chemokines in the gastric mucosa and suppresses bacterial colonization in a mouse model of Helicobacter pylori infection[1]S Raghavan, [2]J Nyström, [3]M Fredriksson, [4]Jan Holmgren, [5]A M Harandi [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.71.12.7014-7022.2003
PubMed: 14638791
Helicobacter pylori [curation]; Helicobacter pylori infectious disease [curation]2003-12-01
Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges[1]Jan Holmgren, [2]Cecil Czerkinsky, [3]Kristina Eriksson, [4]Ali Mharandi [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(03)00206-8
PubMed: 12763689
2003-06-01
Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice[1]S Raghavan, [2]M Fredriksson, [3]A-M Svennerholm, [4]Jan Holmgren, [5]E Suri-Payer [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1046/J.1365-2249.2003.02177.X
PubMed: 12780684
pathology [curation]; Helicobacter pylori [curation]2003-06-01
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.[1]Jan Holmgren, [2]Ali M Harandi, [3]Cecil Czerkinsky [Full author list]Expert Review of Vaccines [curation]DOI: 10.1586/14760584.2.2.205
PubMed: 12899572
cholera [curation]2003-04-01
Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development[1]Kristina Eriksson, [2]Margareta Fredriksson, [3]Inger Nordström, [4]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.71.4.1740-1747.2003
PubMed: 12654787
cholera [curation]; dendritic cell [curation]2003-04-01
Recent developments in mucosal immunomodulatory adjuvants[1]Ali M Harandi, [2]Joaquin Sanchez, [3]Kristina Eriksson, [4]Jan Holmgren [Full author list]Current Opinion in Investigational Drugs [curation]PubMed: 126693752003-02-01
A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection[1]Ali M Harandi, [2]Kristina Eriksson, [3]Jan Holmgren [Full author list]Journal of Virology [curation]DOI: 10.1128/JVI.77.2.953-962.2003
PubMed: 12502811
genital herpes [curation]2003-01-01
Prevention of mucosally induced uveitis with a HSP60-derived peptide linked to cholera toxin B subunit[1]Paula A Phipps, [2]Miles R Stanford, [3]Jia-Bin Sun, [4]Bao-Guo Xiao, [5]Jan Holmgren, [6]Thomas Shinnick, [7]Adam Hasan, [8]Yutaka Mizushima, [9]Thomas Lehner [Full author list]European Journal of Immunology [curation]DOI: 10.1002/IMMU.200390025
PubMed: 12594851
cholera [curation]; uveitis [curation]2003-01-01
Protection against experimental Helicobacter pylori infection after immunization with inactivated H. pylori whole-cell vaccines[1]S Raghavan, [2]M Hjulström, [3]Jan Holmgren, [4]A-M Svennerholm [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.70.11.6383-6388.2002
PubMed: 12379718
Helicobacter pylori [curation]; immunization [curation]; Helicobacter pylori infectious disease [curation]2002-11-01
Recent advances in mucosal vaccines and adjuvants[1]Kristina Eriksson, [2]Jan Holmgren [Full author list]Current Opinion in Immunology [curation]DOI: 10.1016/S0952-7915(02)00384-9
PubMed: 12183170
2002-10-01
Effects of oral vaccination and immunomodulation by cholera toxin on experimental Helicobacter pylori infection, reinfection, and gastritis[1]S Raghavan, [2]A-M Svennerholm, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.70.8.4621-4627.2002
PubMed: 12117975
cholera [curation]; Helicobacter pylori [curation]; Helicobacter pylori infectious disease [curation]2002-08-01
Detoxification of cholera toxin without removal of its immunoadjuvanticity by the addition of (STa-related) peptides to the catalytic subunit. A potential new strategy to generate immunostimulants for vaccination[1]Joaquín Sánchez, [2]Gun Wallerström, [3]Margareta Fredriksson, [4]Jonas Angström, [5]Jan Holmgren [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.M112337200
PubMed: 12089141
cholera [curation]2002-06-27
Genetic fusion of human insulin B-chain to the B-subunit of cholera toxin enhances in vitro antigen presentation and induction of bystander suppression in vivo.[1]Hamid Sadeghi, [2]Søren Bregenholt, [3]Dale Wegmann, [4]Jacob S Petersen, [5]Jan Holmgren, [6]Michael Lebens [Full author list]Immunology [curation]DOI: 10.1046/J.1365-2567.2002.01413.X
PubMed: 12047753
cholera [curation]2002-06-01
Investigations into the safety and immunogenicity of a killed oral cholera vaccine developed in Viet Nam.[1]Trach DD, [2]Cam PD, [3]Ke NT, [4]Rao MR, [5]Dinh D, [6]Hang PV, [7]Hung NV, [8]Canh DG, [9]Thiem VD, [10]Naficy A, [11]Ivanoff B, [12]Ann-Mari Svennerholm, [13]Jan Holmgren, [14]Clemens JD [Full author list]Bulletin of the World Health Organization [curation]PubMed: 11884967Vietnam [curation]; cholera [curation]2002-01-01
Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans[1]E L Johansson, [2]L Wassén, [3]Jan Holmgren, [4]M Jertborn, [5]A Rudin [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.12.7481-7486.2001
PubMed: 11705923
antibody [curation]2001-12-01
Protective vaccination against genital herpes simplex virus type 2 (HSV-2) infection in mice is associated with a rapid induction of local IFN-gamma-dependent RANTES production following a vaginal viral challenge[1]Harandi AM, [2]Svennerholm B, [3]Jan Holmgren, [4]Eriksson K [Full author list]American Journal of Reproductive Immunology [curation]DOI: 10.1034/J.1600-0897.2001.D01-34.X
PubMed: 11775012
genital herpes [curation]; Human herpesvirus 2 [curation]2001-12-01
Nasal administration of Schistosoma mansoni egg antigen-cholera B subunit conjugate suppresses hepatic granuloma formation and reduces mortality in S. mansoni-infected mice[1]J B Sun, [2]M J Stadecker, [3]Nathalie Mielcarek, [4]M Lakew, [5]B L Li, [6]H J Hernandez, [7]C Czerkinsky, [8]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1046/J.1365-3083.2001.00977.X
PubMed: 11696194
cholera [curation]; Schistosoma mansoni [curation]2001-11-01
Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells[1]A George-Chandy, [2]K Eriksson, [3]M Lebens, [4]I Nordström, [5]E Schön, [6]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.9.5716-5725.2001
PubMed: 11500448
cholera [curation]2001-09-01
Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity[1]Harandi AM, [2]Svennerholm B, [3]Jan Holmgren, [4]Eriksson K [Full author list]Journal of Virology [curation]DOI: 10.1128/JVI.75.14.6705-6709.2001
PubMed: 11413339
interleukins [curation]; genital herpes [curation]; sexual transmission [curation]2001-07-01
Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans[1]M Jertborn, [2]I Nordström, [3]A Kilander, [4]C Czerkinsky, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.6.4125-4128.2001
PubMed: 11349086
cholera [curation]; systemic immune response [curation]2001-06-01
Vaccination with Bordetella pertussis-pulsed autologous or heterologous dendritic cells induces a mucosal antibody response in vivo and protects against infection[1]George-Chandy A, [2]Mielcarek N, [3]Nordström I, [4]Jan Holmgren, [5]Eriksson K [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.6.4120-4124.2001
PubMed: 11349085
Bordetella pertussis [curation]; dendritic cell [curation]2001-06-01
Cost of immunization with a locally produced, oral cholera vaccine in Viet Nam.[1]Naficy AB, [2]Trach DD, [3]Ke NT, [4]Chuc NT, [5]Sorkin A, [6]Rao MR, [7]Sy TH, [8]Thiem VD, [9]Canh DG, [10]Mahoney RT, [11]Jan Holmgren, [12]Ivanoff B, [13]Clemens JD [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(01)00089-5
PubMed: 11395206
Vietnam [curation]; cholera [curation]2001-06-01
Dendritic cell vaccination protects mice against lethality caused by genital herpes simplex virus type 2 infection[1]Schön E, [2]Harandi AM, [3]Nordström I, [4]Jan Holmgren, [5]Eriksson K [Full author list]Journal of Reproductive Immunology [curation]DOI: 10.1016/S0165-0378(00)00094-2
PubMed: 11334992
dendritic cell [curation]; genital herpes [curation]2001-05-01
Effect of pre-existing immunity for systemic and mucosal immune responses to intranasal immunization with group B Streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate[1]X Shen, [2]T Lagergård, [3]Y Yang, [4]M Lindblad, [5]M Fredriksson, [6]G Wallerström, [7]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(00)00532-6
PubMed: 11348699
cholera [curation]; polysaccharide [curation]2001-05-01
Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice[1]Harandi AM, [2]Svennerholm B, [3]Jan Holmgren, [4]Eriksson K [Full author list]Journal of General Virology [curation]DOI: 10.1099/0022-1317-82-4-845
PubMed: 11257190
genital herpes [curation]; sexual transmission [curation]2001-04-01
Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin[1]Nathalie Mielcarek, [2]Hörnquist EH, [3]Johansson BR, [4]Locht C, [5]Abraham SN, [6]Jan Holmgren [Full author list]Cellular Microbiology [curation]DOI: 10.1046/J.1462-5822.2001.00106.X
PubMed: 11260141
Bordetella pertussis [curation]; mast cell [curation]2001-03-01
Group B Streptococcus capsular polysaccharide-cholera toxin B subunit conjugate vaccines prepared by different methods for intranasal immunization[1]X Shen, [2]T Lagergård, [3]Y Yang, [4]M Lindblad, [5]M Fredriksson, [6]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.69.1.297-306.2001
PubMed: 11119518
cholera [curation]; polysaccharide [curation]; immunization [curation]2001-01-01
Preparation and preclinical evaluation of experimental group B streptococcus type III polysaccharide-cholera toxin B subunit conjugate vaccine for intranasal immunization.[1]Shen X, [2]Lagergård T, [3]Yang Y, [4]Lindblad M, [5]Fredriksson M, [6]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(00)00226-7
PubMed: 11115709
cholera [curation]; polysaccharide [curation]; immunization [curation]2000-11-01
Enhanced immunological tolerance against allograft rejection by oral administration of allogeneic antigen linked to cholera toxin B subunit[1]Sun JB, [2]Li BL, [3]Czerkinsky C, [4]Jan Holmgren [Full author list]Clinical Immunology [curation]DOI: 10.1006/CLIM.2000.4927
PubMed: 11027453
cholera [curation]2000-11-01
Systemic and mucosal immune responses in mice after mucosal immunization with group B streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate vaccine[1]X Shen, [2]T Lagergård, [3]Y Yang, [4]M Lindblad, [5]M Fredriksson, [6]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.68.10.5749-5755.2000
PubMed: 10992481
cholera [curation]; polysaccharide [curation]; immunization [curation]2000-10-01
Enterotoxin-specific immunoglobulin E responses in humans after infection or vaccination with diarrhea-causing enteropathogens[1]F Qadri, [2]M Asaduzzaman, [3]C Wennerås, [4]G Mohi, [5]M J Albert, [6]M Abdus Salam, [7]Bradley Sack, [8]M Jertborn, [9]J R McGhee, [10]D A Sack, [11]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.68.10.6077-6081.2000
PubMed: 10992527
diarrhea [curation]; enteropathogen [curation]2000-10-01
Oral administration of cholera toxin B subunit conjugated to myelin basic protein protects against experimental autoimmune encephalomyelitis by inducing transforming growth factor-beta-secreting cells and suppressing chemokine expression[1]J B Sun, [2]B G Xiao, [3]M Lindblad, [4]B L Li, [5]H Link, [6]C Czerkinsky, [7]Jan Holmgren [Full author list]International Immunology [curation]DOI: 10.1093/INTIMM/12.10.1449
PubMed: 11007763
cholera [curation]; experimental autoimmune encephalomyelitis [curation]2000-10-01
Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells.[1]K Eriksson, [2]I Nordström, [3]C Czerkinsky, [4]Jan Holmgren [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1046/J.1365-2249.2000.01282.X
PubMed: 10931143
cholera [curation]2000-08-01
Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice[1]C Rask, [2]Jan Holmgren, [3]M Fredriksson, [4]M Lindblad, [5]I Nordström, [6]J B Sun, [7]C Czerkinsky [Full author list]Clinical & Experimental Allergy [curation]DOI: 10.1046/J.1365-2222.2000.00849.X
PubMed: 10848926
cholera [curation]2000-07-01
Antisense inhibition of delta-opioid receptor gene function in vivo by peptide nucleic acids[1]G L Fraser, [2]Jan Holmgren, [2-Q5811529]Jan Holmgren, [3]P B Clarke, [4]C Wahlestedt [Full author list]Molecular Pharmacology [curation]DOI: 10.1124/MOL.57.4.725
PubMed: 10727518
peptide nucleic acid [curation]2000-04-01
Mucosal and systemic antibody responses after peroral or intranasal immunization: effects of conjugation to enterotoxin B subunits and/or of co-administration with free toxin as adjuvant[1]C Rask, [2]M Fredriksson, [3]M Lindblad, [4]C Czerkinsky, [5]Jan Holmgren [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]DOI: 10.1034/J.1600-0463.2000.D01-42.X
PubMed: 10752686
immunologic adjuvant [curation]2000-03-01
Genital antibody responses in mice after intranasal infection with an attenuated candidate vector strain of Bordetella pertussis[1]Nathalie Mielcarek, [2]I Nordström, [3]F D Menozzi, [4]C Locht, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.68.2.485-491.2000
PubMed: 10639408
Bordetella pertussis [curation]; vector-borne disease [curation]2000-02-01
Novel carbohydrate binding site recognizing blood group A and B determinants in a hybrid of cholera toxin and Escherichia coli heat-labile enterotoxin B-subunits[0]Niclas G Karlsson, [1]J Angström, [2]M Bäckström, [3]A Berntsson, [4]N Karlsson, [5]Jan Holmgren, [6]K A Karlsson, [7]M Lebens, [8]S Teneberg [Full author list]Journal of Biological Chemistry [curation]DOI: 10.1074/JBC.275.5.3231
PubMed: 10652309
cholera [curation]; Escherichia coli [curation]2000-02-01
Diagnostic tests, treatment and follow-up in heart failure patients--is there a gender bias in the coherence to guidelines?[1]Mejhert M, [2]Jan Holmgren, [3]Per Wändell, [4]Persson H, [5]Edner M [Full author list]European Journal of Heart Failure [curation]DOI: 10.1016/S1388-9842(99)00053-7
PubMed: 10937955
heart failure [curation]; bias [curation]; gender bias [curation]1999-12-01
Anatomic segmentation of the intestinal immune response in nonhuman primates: differential distribution of B cells after oral and rectal immunizations to sites defined by their source of vascularization[1]K Eriksson, [2]M Quiding-Järbrink, [3]J Osek, [4]I Nordström, [5]M Hjulström, [6]Jan Holmgren, [7]C Czerkinsky [Full author list]Infection and Immunity [curation]PubMed: 10531293immunization [curation]1999-11-01
Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells[1]C Ploix, [2]I Bergerot, [3]A Durand, [4]C Czerkinsky, [5]Jan Holmgren, [6]C Thivolet [Full author list]Diabetes [curation]DOI: 10.2337/DIABETES.48.11.2150
PubMed: 10535448
cholera [curation]1999-11-01
Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy[1]Ursula Wiedermann, [2]Jahn-Schmid B, [3]Lindblad M, [4]Rask C, [5]Jan Holmgren, [6]Kraft D, [7]Ebner C [Full author list]International Immunology [curation]DOI: 10.1093/OXFORDJOURNALS.INTIMM.A019877
PubMed: 10508190
cholera [curation]; murine model [curation]1999-10-01
Mucosal immunity and tolerance: relevance to vaccine development[1]Czerkinsky C, [2]Anjuere F, [3]McGhee JR, [4]George-Chandy A, [5]Jan Holmgren, [6]Kieny MP, [7]Fujiyashi K, [8]Mestecky JF, [9]Pierrefite-Carle V, [10]Rask C, [11]Sun JB [Full author list]Immunological Reviews [curation]DOI: 10.1111/J.1600-065X.1999.TB01339.X
PubMed: 10566152
vaccine [curation]1999-08-01
Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit[1]A Rudin, [2]G C Riise, [3]J Holmgren, [3-Q5811529]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.67.6.2884-2890.1999
PubMed: 10338495
cholera [curation]; antibody [curation]1999-06-01
Distribution of lymphocytes and adhesion molecules in human cervix and vagina[1]E L Johansson, [2]A Rudin, [3]L Wassén, [4]Jan Holmgren [Full author list]Immunology [curation]DOI: 10.1046/J.1365-2567.1999.00675.X
PubMed: 10233705
1999-02-01
Specific-antibody-secreting cells in the rectums and genital tracts of nonhuman primates following vaccination[1]K Eriksson, [2]M Quiding-Järbrink, [3]J Osek, [4]A Möller, [5]S Björk, [6]Jan Holmgren, [7]C Czerkinsky [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.66.12.5889-5896.1998
PubMed: 9826370
1998-12-01
Regulation of mammalian ornithine decarboxylase[1]Persson L, [2]Wallström EL, [3]Nasizadeh S, [4]Dartsch C, [5]Jeppsson A, [6]Wendt A, [7]Jan Holmgren [Full author list]Biochemical Society Transactions [curation]DOI: 10.1042/BST0260575
PubMed: 10047785
1998-11-01
[Duchenne muscular dystrophy. Effects of vitamin E administration on urinary luminescence][1]Pizarro M, [2]Lissi E, [3]Reyes J, [4]Jan Holmgren [Full author list]Revista médica de Chile [curation]PubMed: 100300871998-10-01
Differential kinetics and distribution of antibodies in serum and nasal and vaginal secretions after nasal and oral vaccination of humans[1]A Rudin, [2]E L Johansson, [3]C Bergquist, [4]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.66.7.3390-3396.1998
PubMed: 9632610
antibody [curation]1998-07-01
Enteric infections in an endemic area induce a circulating antibody-secreting cell response with homing potentials to both mucosal and systemic tissues.[1]Qadri F, [2]Mäkelä PH, [3]Jan Holmgren, [4]Albert MJ, [5]Mannoor K, [6]Kantele A, [7]Saha D, [8]Salam MA, [9]Kantele JM [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1086/515306
PubMed: 9607838
1998-06-01
Antibodies and antibody-secreting cells in the female genital tract after vaginal or intranasal immunization with cholera toxin B subunit or conjugates[1]E L Johansson, [2]C Rask, [3]M Fredriksson, [4]K Eriksson, [5]C Czerkinsky, [6]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 9453604cholera [curation]; antibody [curation]; immunization [curation]1998-02-01
Safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli vaccine.[1]Jertborn M, [2]Ahrén C, [3]Jan Holmgren, [4]Ann-Mari Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(97)00169-2
PubMed: 9607039
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]1998-01-01
Induction and expression of intestinal humoral immunity in HIV-infected individuals: prospects for vaccination against secondary enteric infections[1]K Eriksson, [2]A Kilander, [3]L Hagberg, [4]G Norkrans, [5]Jan Holmgren, [6]C Czerkinsky [Full author list]Pathobiology [curation]DOI: 10.1159/000028018
PubMed: 9693321
1998-01-01
Structural basis for differential receptor binding of cholera and Escherichia coli heat-labile toxins: influence of heterologous amino acid substitutions in the cholera B-subunit.[1]Bäckström M, [2]Shahabi V, [3]Johansson S, [4]Teneberg S, [5]Kjellberg A, [6]Miller-Podraza H, [7]Jan Holmgren, [8]Lebens M [Full author list]Molecular Microbiology [curation]DOI: 10.1046/J.1365-2958.1997.3541721.X
PubMed: 9179843
cholera [curation]; Escherichia coli [curation]1997-05-01
Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responses[1]Quiding-Järbrink M, [2]Nordström I, [3]Granström G, [4]Kilander A, [5]Jertborn M, [6]Butcher EC, [7]Lazarovits AI, [8]Jan Holmgren, [9]Czerkinsky C [Full author list]Journal of Clinical Investigation [curation]DOI: 10.1172/JCI119286
PubMed: 9077537
antibody [curation]; immunization [curation]1997-03-01
Intestinal and systemic immune responses in humans after oral immunization with a bivalent B subunit-O1/O139 whole cell cholera vaccine[1]Jertborn M, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(96)00071-0
PubMed: 8994322
cholera [curation]; immunization [curation]; systemic immune response [curation]1996-10-01
Immune mechanisms and protective antigens of Vibrio cholerae serogroup O139 as a basis for vaccine development[1]Jonson G, [2]Osek J, [3]Ann-Mari Svennerholm, [4]Holmgren J, [4-Q5811529]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.64.9.3778-3785.1996
PubMed: 8751929
Vibrio cholerae [curation]1996-09-01
Relative significance of mannose-sensitive hemagglutinin and toxin-coregulated pili in colonization of infant mice by Vibrio cholerae El Tor.[1]Attridge SR, [2]Manning PA, [3]Jan Holmgren, [4]Jonson G [Full author list]Infection and Immunity [curation]PubMed: 8757877Vibrio cholerae [curation]1996-08-01
Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit[1]Sun JB, [2]Rask C, [3]Olsson T, [4]Jan Holmgren, [5]Czerkinsky C [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.93.14.7196
PubMed: 8692968
cholera [curation]; experimental autoimmune encephalomyelitis [curation]1996-07-01
Synthesis of hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits: potential for use in a broad-spectrum vaccine[1]Lebens M, [2]Shahabi V, [3]Bäckström M, [4]Houze T, [5]Lindblad N, [6]Holmgren J, [6-Q5811529]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 8675319cholera [curation]1996-06-01
European Commission COST/STD Initiative. Report of the expert panel VI. Concerted efforts in the field of mucosal immunology[1]Jan Holmgren, [2]Brantzaeg P, [3]Capron A, [4]Francotte M, [5]Mogens Kilian, [6]Kraehenbuhl JP, [7]Lehner T, [8]Seljelid R [Full author list]Vaccine [curation]DOI: 10.1016/S0264-410X(96)90048-1
PubMed: 8799979
1996-05-01
Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity[1]Czerkinsky C, [2]Sun JB, [3]Lebens M, [4]Li BL, [5]Rask C, [6]Lindblad M, [7]Jan Holmgren [Full author list]Annals of the New York Academy of Sciences [curation]DOI: 10.1111/J.1749-6632.1996.TB21127.X
PubMed: 8610972
cholera [curation]1996-02-01
Field trial of inactivated oral cholera vaccines in Bangladesh: results from 5 years of follow-up[1]van Loon FP, [2]Clemens JD, [3]Chakraborty J, [4]Rao MR, [5]Kay BA, [6]Sack DA, [7]Yunus M, [8]Ali M, [9]Ann-Mari Svennerholm, [10]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(95)00122-H
PubMed: 8852414
Bangladesh [curation]; cholera [curation]1996-02-01
Characterization of an internal permissive site in the cholera toxin B-subunit and insertion of epitopes from human immunodeficiency virus-1, hepatitis B virus and enterotoxigenic Escherichia coli[1]Bckström M, [2]Jan Holmgren, [3]Schödel F, [4]Lebens M [Full author list]Gene [curation]DOI: 10.1016/0378-1119(95)00444-B
PubMed: 8522171
Hepatitis B virus [curation]; cholera [curation]; Escherichia coli [curation]1995-11-01
Virus-specific antibody production and polyclonal B-cell activation in the intestinal mucosa of HIV-infected individuals[1]Eriksson K, [2]Kilander A, [3]Hagberg L, [4]Norkrans G, [5]Jan Holmgren, [6]Czerkinsky C [Full author list]AIDS [curation]DOI: 10.1097/00002030-199507000-00005
PubMed: 7546413
1995-07-01
Induction of compartmentalized B-cell responses in human tonsils[1]Quiding-Järbrink M, [2]Granström G, [3]Nordström I, [4]Holmgren J, [4-Q5811529]Jan Holmgren, [5]Czerkinsky C [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.63.3.853-857.1995
PubMed: 7868256
1995-03-01
Impaired mucosal immune response in vitamin A deficient rats immunized with oral cholera vaccine[1]Ursula Wiedermann, [2]L A Hanson, [3]Jan Holmgren, [4]U I Dahlgren [Full author list]Advances in Experimental Medicine and Biology [curation]PubMed: 7502871cholera [curation]; vitamin A [curation]1995-01-01
Infection of vaginal and colonic epithelial cells by the human immunodeficiency virus type 1 is neutralized by antibodies raised against conserved epitopes in the envelope glycoprotein gp120.[1]Y Furuta, [2]K Eriksson, [3]B Svennerholm, [4]P Fredman, [5]P Horal, [6]S Jeansson, [7]A Vahlne, [8]Jan Holmgren, [9]C Czerkinsky [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.91.26.12559
PubMed: 7809077
1994-12-01
Insertion of a HIV-1-neutralizing epitope in a surface-exposed internal region of the cholera toxin B-subunit[1]M. Bäckström, [2]Michael Lebens, [3]F. Schödel, [4]Jan Holmgren [Full author list]Gene [curation]DOI: 10.1016/0378-1119(94)90152-X
PubMed: 7525413
cholera [curation]1994-11-18
Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance[1]Sun JB, [2]Jan Holmgren, [3]Czerkinsky C [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.91.23.10795
PubMed: 7526379
cholera [curation]1994-11-01
The maltose regulon of Vibrio cholerae affects production and secretion of virulence factors[1]Lång H, [2]Jonson G, [3]Jan Holmgren, [4]Palva ET [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.62.11.4781-4788.1994
PubMed: 7927755
Vibrio cholerae [curation]1994-11-01
Immunological memory after immunization with oral cholera B subunit--whole-cell vaccine in Swedish volunteers.[1]Jertborn M, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(94)90176-7
PubMed: 7998416
cholera [curation]; immunization [curation]; immunological memory [curation]1994-09-01
Role of antibodies against biotype-specific Vibrio cholerae pili in protection against experimental classical and El Tor cholera[1]Osek J, [2]Jonson G, [3]Ann-Mari Svennerholm, [4]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.62.7.2901-2907.1994
PubMed: 7911787
cholera [curation]; antibody [curation]; Vibrio cholerae [curation]; El Tor cholera [curation]1994-07-01
Cloning and sequencing of Vibrio cholerae mannose-sensitive haemagglutinin pilin gene: localization of mshA within a cluster of type 4 pilin genes[1]Jonson G, [2]Lebens M, [3]Jan Holmgren [Full author list]Molecular Microbiology [curation]DOI: 10.1111/J.1365-2958.1994.TB00406.X
PubMed: 7984085
Vibrio cholerae [curation]1994-07-01
Structure and arrangement of the cholera toxin genes in Vibrio cholerae O139.[1]Lebens M, [2]Jan Holmgren [Full author list]FEMS Microbiology Letters [curation]DOI: 10.1016/0378-1097(94)90194-5
PubMed: 8181723
cholera [curation]; Vibrio cholerae [curation]1994-04-01
Intestinal and circulating antibody-forming cells in IgA-deficient individuals after oral cholera vaccination[1]V Friman, [2]M Quiding, [3]C Czerkinsky, [4]I Nordström, [5]L Larsson, [6]D Ericson, [7]J Björkander, [8]K Theman, [9]A Kilander, [10]Jan Holmgren [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1111/J.1365-2249.1994.TB06514.X
PubMed: 8306495
cholera [curation]1994-02-01
Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited[1]Jan Holmgren, [1-Q5811529]Jan Holmgren [Full author list]Progress in Brain Research [curation]DOI: 10.1016/S0079-6123(08)61947-0
PubMed: 8029448
cholera [curation]; Escherichia coli [curation]1994-01-01
Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant[1]Jan Holmgren, [2]Czerkinsky C, [3]Nils Y. Lycke, [4]Ann-Mari Svennerholm [Full author list]American Journal of Tropical Medicine and Hygiene [curation]PubMed: 8203723cholera [curation]1994-01-01
Exploration of mucosal immunity in humans: relevance to vaccine development.[1]Czerkinsky C, [2]Jan Holmgren [Full author list]Cellular and Molecular Biology [curation]PubMed: 79508601994-01-01
Mucosal vaccines based on the use of cholera toxin B subunit as immunogen and antigen carrier.[1]Lebens M, [2]Jan Holmgren [Full author list]Developments in Biologicals [curation]PubMed: 7958476cholera [curation]1994-01-01
Large-scale production of Vibrio cholerae toxin B subunit for use in oral vaccines[1]Lebens M, [2]Johansson S, [3]Osek J, [4]Lindblad M, [5]Jan Holmgren [Full author list]Bio/technology [curation]DOI: 10.1038/NBT1293-1574
PubMed: 7764248
Vibrio cholerae [curation]1993-12-01
Immunological characterization of a rotavirus-neutralizing epitope fused to the cholera toxin B subunit[1]R A González, [2]Joaquín Sánchez, [3]Jan Holmgren, [4]Susana López Charreton, [5]C F Arias [Full author list]Gene [curation]DOI: 10.1016/0378-1119(93)90643-H
PubMed: 7693553
cholera [curation]1993-11-01
Impaired mucosal antibody response to cholera toxin in vitamin A-deficient rats immunized with oral cholera vaccine[1]Ursula Wiedermann, [2]Hanson LA, [3]Jan Holmgren, [4]Kahu H, [5]Dahlgren UI [Full author list]Infection and Immunity [curation]PubMed: 8359917cholera [curation]; vitamin A [curation]; immunization [curation]1993-09-01
Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems[1]Jan Holmgren, [2]Nils Y. Lycke, [3]Czerkinsky C [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(93)90039-Z
PubMed: 8256498
cholera [curation]1993-09-01
Extracellular secretion of STa heat-stable enterotoxin by Escherichia coli after fusion to a heterologous leader peptide[1]Joaquín Sánchez, [2]R M Solorzano, [3]Jan Holmgren [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(93)80885-X
PubMed: 8375497
Escherichia coli [curation]1993-09-01
The design and analysis of cholera vaccine trials: recent lessons from Bangladesh[1]J Clemens, [2]D Sack, [3]M Rao, [4]J Chakraborty, [5]B Kay, [6]F Ahmed, [7]M R Khan, [8]F P van Loon, [9]Ann-Mari Svennerholm, [10]Jan Holmgren [Full author list]International Journal of Epidemiology [curation]DOI: 10.1093/IJE/22.4.724
PubMed: 8225749
Bangladesh [curation]; cholera [curation]; vaccine engineering [curation]1993-08-01
Intestinal antibody responses to oral vaccination in HIV-infected individuals[1]K Eriksson, [2]A Kilander, [3]L Hagberg, [4]G Norkrans, [5]Jan Holmgren, [6]C Czerkinsky [Full author list]AIDS [curation]DOI: 10.1097/00002030-199308000-00010
PubMed: 8397945
1993-08-01
B-cell activation in duodenal mucosa after oral cholera vaccination in IgA deficient subjects with or without IgG subclass deficiency[1]D E Nilssen, [2]V Friman, [3]K Theman, [4]J Björkander, [5]A Kilander, [6]Jan Holmgren, [7]L A Hanson, [8]P Brandtzaeg [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1993.TB01714.X
PubMed: 8346420
cholera [curation]1993-08-01
Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells[1]Bromander AK, [2]Kjerrulf M, [3]Jan Holmgren, [4]Nils Y. Lycke [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1993.TB03318.X
PubMed: 8469928
cholera [curation]1993-04-01
Induction and assessment of immunity at enteromucosal surfaces in humans: implications for vaccine development[1]Czerkinsky C, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Clinical Infectious Diseases [curation]DOI: 10.1093/CLINIDS/16.SUPPLEMENT_2.S106
PubMed: 8452962
1993-03-01
Sensitization and development of tolerance via the gut[1]Hanson LA, [2]Telemo E, [3]Ursula Wiedermann, [4]Dahlman A, [5]Saalman R, [6]Ahlstedt S, [7]Friman V, [8]Jan Holmgren, [9]Czerkinsky C, [10]Dahlgren U [Full author list]Pediatric Allergy & Immunology [curation]DOI: 10.1111/J.1399-3038.1993.TB00326.X
PubMed: 8348258
1993-01-01
Intestinal antibody response after oral immunization with a prototype cholera B subunit — colonization factor antigen enterotoxigenic Escherichia coli vaccine[1]Christina Åhrén, [2]Christine Wennerås, [3]Jan Holmgren, [3-Q5811529]Jan Holmgren, [4]Ann-Mari Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(93)90380-G
PubMed: 8212839
cholera [curation]; Escherichia coli [curation]; vaccine [curation]; enterotoxigenic Escherichia coli [curation]1993-01-01
High frequency of spontaneous interferon-gamma-producing cells in human tonsils: role of local accessory cells and soluble factors[1]M Quiding, [2]G Granström, [3]I Nordström, [4]B Ferrua, [5]Jan Holmgren, [6]C Czerkinsky [Full author list]Clinical and Experimental Immunology [curation]DOI: 10.1111/J.1365-2249.1993.TB03372.X
PubMed: 8093434
1993-01-01
Intestinal immunoglobulin production after oral cholera vaccination in patients with IgA deficiency with or without IgG subclass deficiency[1]Nilssen DE, [2]Friman V, [3]Theman K, [4]Björkander J, [5]Kilander A, [6]Jan Holmgren, [7]Hanson LA, [8]Brandtzaeg P [Full author list]Immunodeficiency [curation]PubMed: 8167734cholera [curation]1993-01-01
Protection against Vibrio cholerae El Tor infection by specific antibodies against mannose-binding hemagglutinin pili[1]J. Osek, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.60.11.4961-4964.1992
PubMed: 1356934
Vibrio cholerae [curation]1992-11-01
Enzyme-linked immunosorbent assay for determination of antibodies to Vibrio cholerae toxin-coregulated pili[1]J. Osek, [2]G. Jonson, [3]A. M. Svennerholm, [3-Q4981458]Ann-Mari Svennerholm, [4]Jan Holmgren [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]DOI: 10.1111/J.1699-0463.1992.TB04036.X
PubMed: 1361754
Vibrio cholerae [curation]; ELISEA [curation]1992-11-01
Analysis of expression of toxin-coregulated pili in classical and El Tor Vibrio cholerae O1 in vitro and in vivo[1]G. Jonson, [2]Jan Holmgren, [3]A. M. Svennerholm, [3-Q4981458]Ann-Mari Svennerholm [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.60.10.4278-4284.1992
PubMed: 1356927
Vibrio cholerae [curation]1992-10-01
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity[1]N. Lycke, [1-Q76735921]Nils Y. Lycke, [2]T. Tsuji, [3]Jan Holmgren [Full author list]European Journal of Immunology [curation]DOI: 10.1002/EJI.1830220915
PubMed: 1381311
Escherichia coli [curation]; Vibrio cholerae [curation]; Escherichia coli proteins [curation]1992-09-01
Amplified ELISPOT assay for the detection of HIV-specific antibody-secreting cells in subhuman primates[1]K. Eriksson, [2]I. Nordström, [3]P. Horal, [4]S. Jeansson, [5]B. Svennerholm, [6]A. Vahlne, [7]Jan Holmgren, [8]C. Czerkinsky [Full author list]Journal of Immunological Methods [curation]DOI: 10.1016/0022-1759(92)90312-H
PubMed: 1517581
1992-08-30
Cholera as a model for research on mucosal immunity and development of oral vaccines[1]Jan Holmgren, [2]C. Czerkinsky [Full author list]Current Opinion in Immunology [curation]DOI: 10.1016/S0952-7915(06)80027-0
PubMed: 1388838
cholera [curation]1992-08-01
Bacterial enteric infections and vaccine development[1]Jan Holmgren, [2]Svennerholm AM, [2-Q4981458]Ann-Mari Svennerholm [Full author list]Gastroenterology Clinics of North America [curation]PubMed: 15120461992-06-01
Mucosal immunity: implications for vaccine development[1]Jan Holmgren, [2]Czerkinsky C, [3]Nils Y. Lycke, [4]Ann-Mari Svennerholm [Full author list]Immunobiology [curation]DOI: 10.1016/S0171-2985(11)80473-0
PubMed: 1587541
vaccine [curation]1992-02-01
An oral B subunit: whole cell vaccine against cholera[1]Jan Holmgren, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]M. Jertborn, [4]J. Clemens, [5]D. A. Sack, [6]R. Salenstedt, [7]Hans Wigzell [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(92)90324-D
PubMed: 1471411
cholera [curation]; synthetic vaccine [curation]1992-01-01
Safety and immunogenicity of an oral recombinant cholera B subunit-whole cell vaccine in Swedish volunteers[1]M. Jertborn, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(92)90030-N
PubMed: 1539466
Sweden [curation]; cholera [curation]1992-01-01
Coexpression of ganglioside antigen Fuc-GM1, neural-cell adhesion molecule, carcinoembryonic antigen, and carbohydrate tumor-associated antigen CA 50 in lung cancer[1]F. T. Brezicka, [2]S. Olling, [3]B. Bergman, [4]H. Berggren, [5]C. P. Engström, [6]S. Hammarström, [7]Jan Holmgren, [8]S. Larsson, [9]L. Lindholm [Full author list]Tumor Biology [curation]DOI: 10.1159/000217780
PubMed: 1337798
cell adhesion [curation]1992-01-01
Mucosal immunity and vaccination[1]Jan Holmgren, [1-Q5811529]Jan Holmgren [Full author list]FEMS microbiology immunology [curation]DOI: 10.1111/J.1574-6968.1991.TB04964.X
PubMed: 1815705
1991-12-01
Immunizations of monkeys with synthetic peptides disclose conserved areas on gp120 of human immunodeficiency virus type 1 associated with cross-neutralizing antibodies and T-cell recognition[1]Vahlne A, [2]Horal P, [3]Eriksson K, [4]Jeansson S, [5]Rymo L, [6]Hedström KG, [7]Czerkinsky C, [8]Jan Holmgren, [9]Svennerholm B [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.88.23.10744
PubMed: 1961741
antibody [curation]; immunization [curation]1991-12-01
Identification of a mannose-binding pilus on Vibrio cholerae El Tor.[1]Jonson G, [2]Jan Holmgren, [3]Ann-Mari Svennerholm [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/0882-4010(91)90039-D
PubMed: 1686631
Vibrio cholerae [curation]1991-12-01
Epitope differences in toxin-coregulated pili produced by classical and El Tor Vibrio cholerae O1.[1]Jonson G, [2]Jan Holmgren, [3]Ann-Mari Svennerholm [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/0882-4010(91)90048-F
PubMed: 1724789
Vibrio cholerae [curation]1991-09-01
Immunohistochemical detection of two small cell lung carcinoma-associated antigens defined by MAbs F12 and 123C3 in bronchoscopy biopsy tissues[1]F. T. Brezicka, [2]S. Olling, [3]B. Bergman, [4]H. Berggren, [5]C. P. Engström, [6]Jan Holmgren, [7]S. Larsson, [8]L. Lindholm [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]DOI: 10.1111/J.1699-0463.1991.TB01262.X
PubMed: 1654059
bronchoscopy [curation]; immunohistochemistry [curation]1991-09-01
A recombinant Escherichia coli heat-stable enterotoxin (STa) fusion protein eliciting anti-STa neutralizing antibodies[1]B. Löwenadler, [2]M. Lake, [3]A. Elmblad, [4]Erik Holmgren, [5]Jan Holmgren, [6]A. Karlström, [7]A. M. Svennerholm, [7-Q4981458]Ann-Mari Svennerholm [Full author list]FEMS Microbiology Letters [curation]DOI: 10.1016/0378-1097(91)90273-D
PubMed: 1769524
Escherichia coli [curation]1991-08-15
Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory[1]Quiding M, [2]Nordström I, [3]Kilander A, [4]Andersson G, [5]Hanson LA, [6]Jan Holmgren, [7]Czerkinsky C [Full author list]Journal of Clinical Investigation [curation]DOI: 10.1172/JCI115270
PubMed: 1905327
cholera [curation]; antibody [curation]; immunological memory [curation]1991-07-01
Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro[1]Bromander A, [2]Jan Holmgren, [3]Nils Y. Lycke [Full author list]Journal of Immunology [curation]PubMed: 1901890cholera [curation]1991-05-01
Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans[1]Czerkinsky C, [2]Ann-Mari Svennerholm, [3]Quiding M, [4]Jonsson R, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 1997444cholera [curation]; antibody [curation]1991-03-01
Synthesis in Vibrio cholerae and secretion of hepatitis B virus antigens fused to Escherichia coli heat-labile enterotoxin subunit B[1]F Schödel, [2]H Will, [3]S Johansson, [4]Joaquín Sánchez, [5]Jan Holmgren [Full author list]Gene [curation]DOI: 10.1016/0378-1119(91)90135-X
PubMed: 2022336
Hepatitis B virus [curation]; Escherichia coli [curation]; Vibrio cholerae [curation]1991-03-01
Ceruloplasmin in patients with Duchenne muscular dystrophy[1]Reyes J, [2]Jan Holmgren, [3]Colombo M [Full author list]Revista médica de Chile [curation]PubMed: 1842117Duchenne muscular dystrophy [curation]1991-03-01
Swedish Agency for Research Cooperation with Developing Countries. Prospects for public health benefits in developing countries from new vaccines against enteric infections[1]Sack DA, [2]Freij L, [3]Jan Holmgren [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/163.3.503
PubMed: 1671681
public health [curation]; cooperation [curation]1991-03-01
Recombinant fusion protein for simple detection of Escherichia coli heat-stable enterotoxin by GM1 enzyme-linked immunosorbent assay[1]Sanchez J, [2]Jan Holmgren, [3]Ann-Mari Svennerholm [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.28.10.2175-2177.1990
PubMed: 2229340
Escherichia coli [curation]; ELISEA [curation]1990-10-01
Recombinant cholera toxin B subunit and gene fusion proteins for oral vaccination.[1]Sanchez J, [2]Johansson S, [3]Löwenadler B, [4]Ann-Mari Svennerholm, [5]Jan Holmgren [Full author list]Research in Microbiology [curation]DOI: 10.1016/0923-2508(90)90137-F
PubMed: 2101488
cholera [curation]1990-09-01
Purification of El Tor cholera enterotoxins and comparisons with classical toxin[1]Dubey RS, [2]Lindblad M, [3]Jan Holmgren [Full author list]Journal of General Microbiology [curation]DOI: 10.1099/00221287-136-9-1839
PubMed: 1704409
microbiology [curation]; cholera [curation]; El Tor cholera [curation]1990-09-01
Roles of different coli surface antigens of colonization factor antigen II in colonization by and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits[1]Ann-Mari Svennerholm, [2]Wennerås C, [3]Jan Holmgren, [4]McConnell MM, [5]Rowe B [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.58.2.341-346.1990
PubMed: 1967593
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]1990-02-01
Development of oral vaccines against cholera and enterotoxinogenic Escherichia coli diarrhea[1]Jan Holmgren, [2]Ann-Mari Svennerholm [Full author list]Scandinavian journal of infectious diseases. Supplementum [curation]PubMed: 2102020cholera [curation]; Escherichia coli [curation]; diarrhea [curation]1990-01-01
New vaccines against bacterial enteric infections[1]Jan Holmgren, [2]Ann-Mari Svennerholm [Full author list]Scandinavian journal of infectious diseases. Supplementum [curation]PubMed: 22878971990-01-01
The binding of colonization factor antigens of enterotoxigenic Escherichia coli to intestinal cell membrane proteins[1]Wennerås C, [2]Jan Holmgren, [3]Ann-Mari Svennerholm [Full author list]FEMS Microbiology Letters [curation]DOI: 10.1016/0378-1097(90)90266-S
PubMed: 1969827
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]; membrane protein [curation]1990-01-01
Fusion of genes encoding Escherichia coli heat-stable enterotoxin and outer membrane protein OmpC[1]H T Saarilahti, [2]E T Palva, [3]J Holmgren, [3-Q5811529]Jan Holmgren, [4]J Sanchez [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.57.11.3663-3665.1989
PubMed: 2680976
Escherichia coli [curation]; membrane protein [curation]1989-11-01
Gamma-interferon-mediated down-regulation of electrolyte secretion by intestinal epithelial cells: a local immune mechanism?[1]Jan Holmgren, [2]Fryklund J, [3]Larsson H [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1989.TB02456.X
PubMed: 2554490
1989-10-01
Development of oral vaccines against enterotoxinogenic Escherichia coli diarrhoea[1]Ann-Mari Svennerholm, [2]Jan Holmgren, [3]Sack DA [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(89)90228-4
PubMed: 2675484
Escherichia coli [curation]; diarrhea [curation]1989-06-01
Vibrio cholerae expresses cell surface antigens during intestinal infection which are not expressed during in vitro culture[1]Jonson G, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.57.6.1809-1815.1989
PubMed: 2722240
Vibrio cholerae [curation]1989-06-01
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues[1]C Czerkinsky, [2]M W Russell, [3]Nils Y. Lycke, [4]M Lindblad, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 2925239cholera [curation]; antibody [curation]1989-04-01
Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin[1]Nils Y. Lycke, [2]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.57.4.1137-1141.1989
PubMed: 2784416
cholera [curation]; immunization [curation]1989-04-01
New cholera vaccines[1]Jan Holmgren, [2]Clemens J, [3]Sack DA, [4]Ann-Mari Svennerholm [Full author list]Vaccine [curation]DOI: 10.1016/0264-410X(89)90042-X
PubMed: 2665353
cholera [curation]1989-04-01
Immunohistological detection of fucosyl-GM1 ganglioside in human lung cancer and normal tissues with monoclonal antibodies[1]Brezicka FT, [2]Olling S, [3]Nilsson O, [4]Bergh J, [5]Jan Holmgren, [6]Sörenson S, [7]Yngvason F, [8]Lindholm L [Full author list]Cancer Research [curation]PubMed: 2645049antibody [curation]1989-03-01
Effects of undernutrition on infection with Vibrio cholerae O1 and on response to oral cholera vaccine[1]Glass RI, [2]Ann-Mari Svennerholm, [3]Stoll BJ, [4]Khan MR, [5]Huda S, [6]Huq MI, [7]Jan Holmgren [Full author list]Pediatric Infectious Disease Journal [curation]PubMed: 2704600cholera [curation]; Vibrio cholerae [curation]; undernutrition [curation]1989-02-01
Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development[1]Sanchez J, [2]Jan Holmgren [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.86.2.481
PubMed: 2492108
cholera [curation]; vaccine [curation]; Vibrio cholerae [curation]; overexpression [curation]1989-01-01
Oral immunization against cholera[1]Jan Holmgren, [2]J Clemens, [3]D A Sack, [4]J Sanchez, [5]Ann-Mari Svennerholm [Full author list]Current Topics in Microbiology and Immunology [curation]PubMed: 2659268cholera [curation]1989-01-01
Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo[1]Nils Y. Lycke, [2]Bromander AK, [3]Ekman L, [4]Karlsson U, [5]Jan Holmgren [Full author list]Journal of Immunology [curation]PubMed: 2783324cholera [curation]; immunologic adjuvant [curation]1989-01-01
Role of local IgA antitoxin-producing cells for intestinal protection against cholera toxin challenge[1]Nils Y. Lycke, [2]A K Bromander, [3]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000234806
PubMed: 2785966
cholera [curation]1989-01-01
Genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin B-subunit[1]Sanchez J, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(88)81041-X
PubMed: 3058509
cholera [curation]1988-12-01
Receptor blocking, cholera, and Escherichia coli toxins[1]W B Greenough, [2]R I Glass, [3]Jan Holmgren, [4]M R Khan, [5]K M Hossain, [6]I Huq [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/158.5.1147-A
PubMed: 2846709
cholera [curation]; Escherichia coli [curation]1988-11-01
Role of PCF8775 antigen and its coli surface subcomponents for colonization, disease, and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits[1]Ann-Mari Svennerholm, [2]Vidal YL, [3]Jan Holmgren, [4]McConnell MM, [5]Rowe B [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.56.2.523-528.1988
PubMed: 3276628
Escherichia coli [curation]; enterotoxigenic Escherichia coli [curation]1988-02-01
Five-year immunologic memory in Swedish volunteers after oral cholera vaccination.[1]Jertborn M, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/157.2.374
PubMed: 3335813
Sweden [curation]; cholera [curation]1988-02-01
Enterotoxigenic Escherichia coli diarrhea in an endemic area prepares the intestine for an anamnestic immunoglobulin A antitoxin response to oral cholera B subunit vaccination[1]J Holmgren, [1-Q5811529]Jan Holmgren, [2]A M Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]L Gothefors, [4]M Jertborn, [4-Q125270282]Jertborn M, [5]B Stoll [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.56.1.230-233.1988
PubMed: 3275584
cholera [curation]; Escherichia coli [curation]; diarrhea [curation]; enterotoxigenic Escherichia coli [curation]1988-01-01
Mucosal immune response to cholera toxin--cellular basis of memory and adjuvant action.[1]Nils Y. Lycke, [2]Jan Holmgren [Full author list]Monographs in allergy [curation]PubMed: 3258956cholera [curation]1988-01-01
IgG and IgA Subclass Distribution of Antitoxin Antibody Responses after Oral Cholera Vaccination or Cholera Disease[1]M. Jertborn, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000234532
PubMed: 3350611
cholera [curation]; immunology [curation]1988-01-01
Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae[1]Hirst TR, [2]Jan Holmgren [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.84.21.7418
PubMed: 3478701
Vibrio cholerae [curation]1987-11-01
Circulating cholera antitoxin memory cells in the blood one year after oral cholera vaccination in humans.[1]Nils Y. Lycke, [2]Hellström U, [3]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1987.TB02253.X
PubMed: 3498210
cholera [curation]1987-08-01
Protective efficacy in humans of killed whole-vibrio oral cholera vaccine with and without the B subunit of cholera toxin[1]Robert E. Black, [2]M M Levine, [3]M L Clements, [4]C R Young, [5]Ann-Mari Svennerholm, [6]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 3552989cholera [curation]; vaccine [curation]1987-05-01
Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization[1]Nils Y. Lycke, [2]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1987.TB02207.X
PubMed: 3576134
cholera [curation]1987-04-01
Protection against cholera toxin after oral immunization is thymus-dependent and associated with intestinal production of neutralizing IgA antitoxin[1]Nils Y. Lycke, [2]L Eriksen, [3]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1987.TB02208.X
PubMed: 3576135
cholera [curation]1987-04-01
Transient entry of enterotoxin subunits into the periplasm occurs during their secretion from Vibrio cholerae[1]Hirst TR, [2]Jan Holmgren [Full author list]Journal of Bacteriology [curation]DOI: 10.1128/JB.169.3.1037-1045.1987
PubMed: 3493239
Vibrio cholerae [curation]1987-03-01
Serum levels of the carcinoma-associated antigen CA 50 in ulcerative colitis.[1]Gronowitz M, [2]Kilander AF, [3]Jan Holmgren, [4]Lindholm L, [5]Persson B, [6]Ahrén C [Full author list]Scandinavian Journal of Gastroenterology [curation]DOI: 10.3109/00365528708991886
PubMed: 3472339
1987-03-01
An oral B subunit-whole cell vaccine against cholera: from concept to successful field trial[1]Jan Holmgren, [2]Ann-Mari Svennerholm, [3]J Clemens, [4]D Sack, [5]R Black, [6]M Levine [Full author list]Advances in Experimental Medicine and Biology [curation]PubMed: 3321938cholera [curation]1987-01-01
Immunoactive chimeric ST-LT enterotoxins of Escherichia coli generated by in vitro gene fusion.[1]Sanchez J, [2]Bernt Eric Uhlin, [3]Grundström T, [4]Jan Holmgren, [5]Hirst TR [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(86)81016-X
PubMed: 2430831
Escherichia coli [curation]1986-11-01
Monoclonal antibodies against Escherichia coli heat-stable toxin (STa) and their use in a diagnostic ST ganglioside GM1-enzyme-linked immunosorbent assay[1]Ann-Mari Svennerholm, [2]Wikström M, [3]Lindblad M, [4]Jan Holmgren [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.24.4.585-590.1986
PubMed: 2429984
Escherichia coli [curation]; antibody [curation]; ELISEA [curation]1986-10-01
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens[1]Nils Y. Lycke, [2]Jan Holmgren [Full author list]Immunology [curation]PubMed: 3021614cholera [curation]1986-10-01
Saliva, breast milk, and serum antibody responses as indirect measures of intestinal immunity after oral cholera vaccination or natural disease[1]Jertborn M, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.24.2.203-209.1986
PubMed: 3528211
cholera [curation]; antibody [curation]; saliva [curation]1986-08-01
Strong biotype and serotype cross-protective antibacterial and antitoxic immunity in rabbits after cholera infection[1]Nils Y. Lycke, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/0882-4010(86)90068-9
PubMed: 3508492
cholera [curation]1986-08-01
Effect of neutralization of gastric acid on immune responses to an oral B subunit, killed whole-cell cholera vaccine[1]J D Clemens, [2]M Jertborn, [3]D Sack, [4]Bonita Stanton, [5]Jan Holmgren, [6]M R Khan, [7]S Huda [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/154.1.175
PubMed: 3519789
cholera [curation]1986-07-01
Expression of the Escherichia coli lamB gene in Vibrio cholerae[1]Harkki A, [2]Hirst TR, [3]Jan Holmgren, [4]Palva ET [Full author list]Microbial Pathogenesis [curation]DOI: 10.1016/0882-4010(86)90053-7
PubMed: 2977630
Escherichia coli [curation]; Vibrio cholerae [curation]1986-06-01
Intestinal mucosal memory and presence of memory cells in lamina propria and Peyer's patches in mice 2 years after oral immunization with cholera toxin.[1]Nils Y. Lycke, [2]Jan Holmgren [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1986.TB01995.X
PubMed: 3704560
cholera [curation]; immunization [curation]1986-05-01
Detection of a ganglioside antigen associated with small cell lung carcinomas using monoclonal antibodies directed against fucosyl-GM1.[1]Nilsson O, [2]Brezicka FT, [3]Jan Holmgren, [4]Sörenson S, [5]Svennerholm L, [6]Yngvason F, [7]Lindholm L [Full author list]Cancer Research [curation]PubMed: 30026161986-03-01
Local and systemic antibody responses to naturally acquired enterotoxigenic Escherichia coli diarrhea in an endemic area[1]B J Stoll, [2]Ann-Mari Svennerholm, [3]L Gothefors, [4]D Barua, [5]S Huda, [6]Jan Holmgren [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/153.3.527
PubMed: 3512729
Escherichia coli [curation]; diarrhea [curation]; enterotoxigenic Escherichia coli [curation]1986-03-01
Binding specificity of monoclonal antibodies to ganglioside, Fuc-GM1[1]P Fredman, [2]T Brezicka, [3]Jan Holmgren, [4]L Lindholm, [5]O Nilsson, [6]L Svennerholm [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/0005-2760(86)90182-7
PubMed: 3942769
monoclonal antibody [curation]1986-02-01
Monoclonal antibodies to Escherichia coli heat-labile enterotoxins: neutralising activity and differentiation of human and porcine LTs and cholera toxin[1]Ann-Mari Svennerholm, [2]Wikström M, [3]Lindblad M, [4]Jan Holmgren [Full author list]Medical Biology [curation]PubMed: 3724258cholera [curation]; Escherichia coli [curation]; monoclonal antibody [curation]1986-01-01
Stool cyclic AMP in diarrhoea due to different causative organisms.[1]Molla A, [2]Lonnroth I, [3]Jahan F, [4]Bardhan PK, [5]Molla AM, [6]Jan Holmgren [Full author list]Journal of Health Population and Nutrition [curation]PubMed: 3016069diarrhea [curation]1985-12-01
Changes in intestinal fluid and mucosal immune responses to cholera toxin in Giardia muris infection and binding of cholera toxin to Giardia muris trophozoites[1]Ljungström I, [2]Jan Holmgren, [3]Ann-Mari Svennerholm, [4]Ferrante A [Full author list]Infection and Immunity [curation]PubMed: 4044038cholera [curation]; Giardia muris [curation]1985-10-01
Cholera antibody production in vitro by peripheral blood lymphocytes following oral immunization of humans and mice.[1]Nils Y. Lycke, [2]Lindholm L, [3]Jan Holmgren [Full author list]Clinical and Experimental Immunology [curation]PubMed: 4064375cholera [curation]; antibody [curation]; immunization [curation]1985-10-01
Monoclonal antibodies raised against NeuAc alpha 2-6neolactotetraosylceramide detect carcinoma-associated gangliosides.[1]O Nilsson, [2]L Lindholm, [3]Jan Holmgren, [4]L Svennerholm [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/0005-2760(85)90127-4
PubMed: 2410031
antibody [curation]1985-07-01
Comparison of receptors for cholera and Escherichia coli enterotoxins in human intestine.[1]Jan Holmgren, [2]M Lindblad, [3]P Fredman, [4]L Svennerholm, [5]H Myrvold [Full author list]Gastroenterology [curation]PubMed: 3891496cholera [curation]; Escherichia coli [curation]1985-07-01
Predisposition for cholera of individuals with O blood group. Possible evolutionary significance[1]Glass RI, [2]Jan Holmgren, [3]Haley CE, [4]Khan MR, [5]Ann-Mari Svennerholm, [6]Stoll BJ, [7]Belayet Hossain KM, [8]Robert E. Black, [9]Yunus M, [10]Barua D [Full author list]American Journal of Epidemiology [curation]DOI: 10.1093/OXFORDJOURNALS.AJE.A114050
PubMed: 4014172
cholera [curation]1985-06-01
Chemical structure of carcinoma ganglioside antigens defined by monoclonal antibody C-50 and some allied gangliosides of human pancreatic adenocarcinoma[1]J E Månsson, [2]P Fredman, [3]O Nilsson, [4]L Lindholm, [5]Jan Holmgren, [6]L Svennerholm [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/0005-2760(85)90182-1
PubMed: 3978112
monoclonal antibody [curation]; pancreatic adenocarcinoma [curation]1985-03-01
Sialosyllactotetraosylceramide, a novel ganglioside antigen detected in human carcinomas by a monoclonal antibody[1]Nilsson O, [2]Månsson JE, [3]Lindholm L, [4]Jan Holmgren, [5]Svennerholm L [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(85)80341-0
PubMed: 2984045
monoclonal antibody [curation]1985-03-01
Non-O1 Vibrio cholerae in Thailand: homology with cloned cholera toxin genes[1]Hanchalay S, [2]Seriwatana J, [3]Echeverria P, [4]Jan Holmgren, [5]Tirapat C, [6]Moseley SL, [7]Taylor DN [Full author list]Journal of Clinical Microbiology [curation]PubMed: 3973005Thailand [curation]; cholera [curation]; Vibrio cholerae [curation]1985-02-01
Seroepidemiological studies of El Tor cholera in Bangladesh: association of serum antibody levels with protection[1]R I Glass, [2]Ann-Mari Svennerholm, [3]M R Khan, [4]S Huda, [5]M I Huq, [6]Jan Holmgren [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/151.2.236
PubMed: 3968450
Bangladesh [curation]; cholera [curation]; antibody [curation]; El Tor cholera [curation]1985-02-01
Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli[1]Hirst TR, [2]Sanchez J, [3]Kaper JB, [4]Hardy SJ, [5]Jan Holmgren [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.81.24.7752
PubMed: 6393126
Escherichia coli [curation]; Vibrio cholerae [curation]1984-12-01
Weak serum and intestinal antibody responses to Vibrio cholerae soluble hemagglutinin in cholera patients[1]Ann-Mari Svennerholm, [2]M M Levine, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.45.3.792-794.1984
PubMed: 6469362
cholera [curation]; Vibrio cholerae [curation]1984-09-01
Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunit-whole cell vaccine.[1]Ann-Mari Svennerholm, [2]Jertborn M, [3]Gothefors L, [4]Karim AM, [5]Sack DA, [6]Jan Holmgren [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/149.6.884
PubMed: 6736680
cholera [curation]; vaccine [curation]; immunization [curation]1984-06-01
Detection by monoclonal antibody of carbohydrate antigen CA 50 in serum of patients with carcinoma[1]Jan Holmgren, [2]Lindholm L, [3]Persson B, [4]Lagergård T, [5]Nilsson O, [6]Svennerholm L, [7]Rudenstam CM, [8]Unsgaard B, [9]Yngvason F, [10]Pettersson S [Full author list]The BMJ [curation]PubMed: 6426610antibody [curation]; monoclonal antibody [curation]1984-05-01
A Randomized, Controlled Trial of the Toxin-Blocking Effects of B Subunit in Family Members of Patients with Cholera[1]R. I. Glass, [2]Jan Holmgren, [3]M. R. Khan, [4]K. M. Hossain, [5]M. I. Huq, [6]W. B. Greenough [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/149.4.495
PubMed: 6373961
cholera [curation]; randomized controlled trial [curation]1984-04-01
Local and systemic antibody responses and immunological memory in humans after immunization with cholera B subunit by different routes[1]Ann-Mari Svennerholm, [2]L Gothefors, [3]D A Sack, [4]P K Bardhan, [5]Jan Holmgren [Full author list]Bulletin of the World Health Organization [curation]PubMed: 6335849cholera [curation]; immunization [curation]; immunological memory [curation]1984-01-01
Gut mucosal, salivary and serum antitoxic and antibacterial antibody responses in Swedes after oral immunization with B subunit-whole cell cholera vaccine[1]M Jertborn, [2]Ann-Mari Svennerholm, [3]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000233587
PubMed: 6746103
cholera [curation]1984-01-01
Purification of Vibrio cholerae soluble hemagglutinin and development of enzyme-linked immunosorbent assays for antigen and antibody quantitations[1]A. M. Svennerholm, [1-Q4981458]Ann-Mari Svennerholm, [2]G. J. Strömberg, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.41.1.237-243.1983
PubMed: 6345393
microbiology [curation]; immunology [curation]; Vibrio cholerae [curation]; ELISEA [curation]; immunoenzyme techniques [curation]1983-07-01
Protection against cholera in breast-fed children by antibodies in breast milk.[1]Glass RI, [2]Ann-Mari Svennerholm, [3]Stoll BJ, [4]Khan MR, [5]Hossain KM, [6]Huq MI, [7]Jan Holmgren [Full author list]The New England Journal of Medicine [curation]DOI: 10.1056/NEJM198306093082304
PubMed: 6843632
cholera [curation]; antibody [curation]; breastfeeding [curation]1983-06-01
Monoclonal antibodies to cholera toxin with special reference to cross-reactions with Escherichia coli heat-labile enterotoxin[1]Lindholm L, [2]Jan Holmgren, [3]Wikström M, [4]Karlsson U, [5]Andersson K, [6]Nils Y. Lycke [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.40.2.570-576.1983
PubMed: 6840852
cholera [curation]; Escherichia coli [curation]; antibody [curation]1983-05-01
Serologic Differentiation Between Antitoxin Responses to Infection with Vibrio cholerae and Enterotoxin-Producing Escherichia coli[1]A. M. Svennerholm, [1-Q4981458]Ann-Mari Svennerholm, [2]Jan Holmgren, [3]R. Black, [4]M. Levine, [5]M. Merson [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/147.3.514
PubMed: 6339647
Escherichia coli [curation]; Vibrio cholerae [curation]; Escherichia coli proteins [curation]1983-03-01
Colorectal carcinomas have a characteristic ganglioside pattern[1]Fredman P, [2]Nilsson O, [3]Svennerholm L, [4]Myrvold H, [5]Persson B, [6]Pettersson S, [7]Jan Holmgren, [8]Lindholm L [Full author list]Medical Biology [curation]PubMed: 68431891983-02-01
Receptor-like glycocompounds in human milk that inhibit classical and El Tor Vibrio cholerae cell adherence (hemagglutination)[1]Jan Holmgren, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]M. Lindblad [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.39.1.147-154.1983
PubMed: 6295953
microbiology [curation]; immunology [curation]; Vibrio cholerae [curation]1983-01-01
Cholera and the immune response[1]Jan Holmgren, [2]Svennerholm AM, [2-Q4981458]Ann-Mari Svennerholm [Full author list]Progress in Allergy [curation]PubMed: 6338509cholera [curation]1983-01-01
Current status of an oral B subunit whole cell cholera vaccine.[1]Ann-Mari Svennerholm, [2]Jertborn M, [3]Gothefors L, [4]Karim A, [5]Sack DA, [6]Jan Holmgren [Full author list]Developments in Biologicals [curation]PubMed: 6873479cholera [curation]1983-01-01
Monoclonal antibodies against gastrointestinal tumour-associated antigens isolated as monosialogangliosides[1]L Lindholm, [2]Jan Holmgren, [3]L Svennerholm, [4]P Fredman, [5]O Nilsson, [6]B Persson, [7]H Myrvold, [8]T Lagergård [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000233384
PubMed: 6840874
monoclonal antibody [curation]1983-01-01
IgA isotype restriction in the mucosal but not in the extramucosal immune response after oral immunizations with cholera toxin or cholera B subunit[1]Nils Y. Lycke, [2]L Lindholm, [3]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000234853
PubMed: 6874106
cholera [curation]1983-01-01
Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin[1]Holmgren J, [1-Q5811529]Jan Holmgren, [2]Fredman P, [3]Lindblad M, [4]Ann-Mari Svennerholm, [5]Svennerholm L [Full author list]Infection and Immunity [curation]PubMed: 7141703cholera [curation]; Escherichia coli [curation]1982-11-01
The use of chlorpromazine in the treatment of cholera and other severe acute watery diarrheal diseases[1]Islam MR, [2]Sack DA, [3]Jan Holmgren, [4]Bardhan PK, [5]Rabbani GH [Full author list]Gastroenterology [curation]PubMed: 7040157cholera [curation]; chlorpromazine [curation]1982-06-01
Controlled trial of chlorpromazine as antisecretory agent in patients with cholera hydrated intravenously[1]G H Rabbani, [2]W B Greenough, [3]J Holmgren, [3-Q5811529]Jan Holmgren, [4]B Kirkwood [Full author list]The BMJ [curation]DOI: 10.1136/BMJ.284.6326.1361
PubMed: 6803977
cholera [curation]; chlorpromazine [curation]1982-05-01
Nonimmunoglobulin fraction of human milk inhibits bacterial adhesion (hemagglutination) and enterotoxin binding of Escherichia coli and Vibrio cholerae[1]Holmgren J, [1-Q5811529]Jan Holmgren, [2]Ann-Mari Svennerholm, [3]Ahrén C [Full author list]Infection and Immunity [curation]PubMed: 7021421Escherichia coli [curation]; Vibrio cholerae [curation]1981-07-01
Actions of cholera toxin and the prevention and treatment of cholera[1]Jan Holmgren [Full author list]Nature [curation]DOI: 10.1038/292413A0
PubMed: 7019725
cholera [curation]1981-07-01
Synthesis of a precursor to the B subunit of heat-labile enterotoxin in Escherichia coli[1]E. T. Palva, [2]T. R. Hirst, [3]S. J. Hardy, [4]Jan Holmgren, [5]L. Randall [Full author list]Journal of Bacteriology [curation]DOI: 10.1128/JB.146.1.325-330.1981
PubMed: 6260742
microbiology [curation]; Escherichia coli [curation]; Escherichia coli proteins [curation]1981-04-01
Receptor-Specific Large-Scale Purification of Cholera Toxin on Silica Beads Derivatized with LysoGM1 Ganglioside[1]J. L. Tayot, [2]Jan Holmgren, [3]L. Svennerholm, [4]M. Lindblad, [5]M. Tardy [Full author list]FEBS Journal [curation]DOI: 10.1111/J.1432-1033.1981.TB05060.X
PubMed: 6258916
biochemistry [curation]; cholera [curation]1981-01-01
Changes in Intestinal Fluid Transport and Immune Responses to Enterotoxins Due to Concomitant Parasitic Infection[1]I. Ljungström, [2]Jan Holmgren, [3]G. Huldt, [4]S. Lange, [5]A. M. Svennerholm, [5-Q4981458]Ann-Mari Svennerholm [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.30.3.734-740.1980
PubMed: 7228388
microbiology [curation]; immunology [curation]1980-12-01
Intestinal immune response to cholera toxin: dependence on route and dosage of antigen for priming and boosting[1]Ann-Mari Svennerholm, [2]Lange S, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 7439981cholera [curation]1980-11-01
Different secretory immunoglobulin A antibody responses to cholera vaccination in Swedish and Pakistani women[1]Ann-Mari Svennerholm, [2]Hanson LA, [3]Jan Holmgren, [4]Lindblad BS, [5]Nilsson B, [6]Quereshi F [Full author list]Infection and Immunity [curation]PubMed: 7439987Sweden [curation]; Pakistan [curation]; cholera [curation]1980-11-01
Binding of intraluminal toxin in cholera: trial of GM1 ganglioside charcoal[1]B. J. Stoll, [2]Jan Holmgren, [3]P. K. Bardhan, [4]I. Huq, [5]W. B. Greenough, [6]P. Fredman, [7]L. Svennerholm [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(80)92049-8
PubMed: 6107548
intestine [curation]; cholera [curation]; charcoal [curation]; intestinal epithelium [curation]1980-10-25
Polystyrene-adsorbed gangliosides for investigation of the structure of the tetanus-toxin receptor[1]Jan Holmgren, [2]H Elwing, [3]P Fredman, [4]L Svennerholm [Full author list]FEBS Journal [curation]DOI: 10.1111/J.1432-1033.1980.TB04583.X
PubMed: 7398619
1980-05-01
Sendai virus receptor: proposed recognition structure based on binding to plastic-adsorbed gangliosides[1]Jan Holmgren, [2]L. Svennerholm, [3]H. Elwing, [4]P. Fredman, [5]O. Strannegård [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.77.4.1947
PubMed: 6246515
Sendai virus [curation]1980-04-01
Antitoxic cholera immunity in mice: influence of antigen deposition on antitoxin-containing cells and protective immunity in different parts of the intestine[1]Lange S, [2]Nygren H, [3]Ann-Mari Svennerholm, [4]Jan Holmgren [Full author list]Infection and Immunity [curation]PubMed: 7189747cholera [curation]1980-04-01
Maternal cholera immunisation and scecretory IgA in breast milk[1]M H Merson, [2]R E Black, [3]D A Sack, [4]Ann-Mari Svennerholm, [5]Jan Holmgren [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(80)90860-0
PubMed: 6103281
cholera [curation]1980-04-01
Gangliosides as receptors for bacterial toxins and Sendai virus[1]Jan Holmgren, [2]H Elwing, [3]P Fredman, [4]O Strannegård, [5]L Svennerholm [Full author list]Advances in Experimental Medicine and Biology [curation]DOI: 10.1007/978-1-4684-7844-0_40
PubMed: 6244724
Sendai virus [curation]1980-01-01
Immunoassays based on plastic-adsorbed gangliosides[1]Jan Holmgren, [2]H Elwing, [3]P Fredman, [4]L Svennerholm [Full author list]Advances in Experimental Medicine and Biology [curation]DOI: 10.1007/978-1-4684-7844-0_32
PubMed: 7361621
1980-01-01
Effect of experimental trichinosis on intestinal secretion and on local antibody formation to cholera toxin[1]Ljungström I, [2]Jan Holmgren, [3]Huldt G, [4]Lange S, [5]Ann-Mari Svennerholm [Full author list]Scandinavian journal of infectious diseases. Supplementum [curation]PubMed: 6937981cholera [curation]; trichinosis [curation]1980-01-01
Evaluation of a ganglioside immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin[1]E. Bäck, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]Jan Holmgren, [4]R. Möllby [Full author list]Journal of Clinical Microbiology [curation]DOI: 10.1128/JCM.10.6.791-795.1979
PubMed: 391815
Escherichia coli [curation]; immunoenzyme techniques [curation]1979-12-01
Chlorpromazine Reverses Diarrhea in Piglets Caused by Enterotoxigenic Escherichia coli[1]I. Lönnroth, [2]B. Andrén, [3]S. Lange, [4]K. Martinsson, [5]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.24.3.900-905.1979
PubMed: 381206
microbiology [curation]; Escherichia coli [curation]; diarrhea [curation]; immunology [curation]; chlorpromazine [curation]1979-06-01
Chlorpromazine reduces fluid-loss in cholera[1]G. H. Rabbani, [2]W. B. Greenough, [3]Jan Holmgren, [4]I. Lönnroth [Full author list]The Lancet [curation]DOI: 10.1016/S0140-6736(79)90885-7
PubMed: 84263
biology [curation]; physiology [curation]; cholera [curation]; chlorpromazine [curation]; clinical research [curation]1979-02-24
In vivo suppression of allograft rejection by cyclic AMP increasing agents[1]Ljungström I, [2]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000232178
PubMed: 217841
1979-01-01
Structural studies of the Vibrio cholerae O-antigen[1]L. Kenne, [2]B. Lindberg, [3]P. Unger, [4]T. Holme, [5]Jan Holmgren [Full author list]Carbohydrate Research [curation]DOI: 10.1016/S0008-6215(00)84073-2
PubMed: 427831
analytical chemistry [curation]; biochemistry [curation]; organic chemistry [curation]; Vibrio cholerae [curation]; bacterial antigens [curation]1979-01-01
Reversal of cyclic AMP-mediated intestinal secretion in mice by chlorpromazine[1]Jan Holmgren, [2]S. Lange, [3]I. Lönnroth [Full author list]Gastroenterology [curation]PubMed: 2133461978-12-01
Protective antitoxic cholera immunity in mice: influence of route and number of immunizations and mode of action of protective antibodies[1]S. Lange, [2]Jan Holmgren [Full author list]Acta pathologica et microbiologica Scandinavica. Section C, Immunology [curation]DOI: 10.1111/J.1699-0463.1978.TB02572.X
PubMed: 696335
cholera [curation]; antibody [curation]; antitoxin [curation]; immunization [curation]; bacterial antibodies [curation]1978-08-01
Correlation between intestinal synthesis of specific immunoglobulin A and protection against experimental cholera in mice[1]Ann-Mari Svennerholm, [2]Lange S, [3]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.21.1.1-6.1978
PubMed: 711308
cholera [curation]1978-07-01
Interaction of cholera toxin and toxin derivatives with lymphocytes. III. Modulating effects in vivo by cholera toxin on the graft-versus-host reactivity of lymphoid cells: suggested inhibition of suppressor cells[1]S. Lange, [2]L. Lindholm, [3]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]PubMed: 26637cholera [curation]; Graft vs Host Reaction [curation]1978-01-01
Development of improved cholera vaccine based on subunit toxoid[1]Jan Holmgren, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]I. Lönnroth, [4]Fall-Persson M, [5]B. Markman, [6]H. Lundbeck [Full author list]Nature [curation]DOI: 10.1038/269602A0
PubMed: 72361
cholera [curation]1977-10-13
Ultrastructural localization of cell membrane GM1 ganglioside by cholera toxin[1]H. A. Hansson, [2]L. Svennerholm, [2-Q5811529]Jan Holmgren [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.74.9.3782
PubMed: 269432
cholera [curation]1977-09-01
Mechanisms of Disease and Immunity in Cholera: A Review[1]Jan Holmgren, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/136.SUPPLEMENT.S105
PubMed: 197173
cholera [curation]; antitoxin [curation]; bacterial antibodies [curation]1977-08-01
In vivo modulation of intracellular cAMP and cell growth of a lymphatic tumour in mice by cholera toxin[1]Jan Holmgren, [2]S. Lange, [3]L. Lindholm, [4]C. Lönnroth, [5]I. Lönnroth [Full author list]Experimental Cell Research [curation]DOI: 10.1016/S0014-4827(77)80006-2
PubMed: 196871
cell biology [curation]; cholera [curation]; cell growth [curation]1977-08-01
Chlorpromazine inhibits cholera toxin-induced intestinal hypersecretion[1]I. Lönnroth, [2]Jan Holmgren, [3]S. Lange [Full author list]Medical Biology [curation]PubMed: 197323cholera [curation]; chlorpromazine [curation]1977-06-01
Antibodies in human serum and milk induced by enterobacteria and food proteins[1]S. Ahlstedt, [2]B. Carlsson, [3]S. P. Fällström, [4]L. A. Hanson, [5]Jan Holmgren, [6]G. Lidin-Janson, [7]B. S. Lindblad, [8]U. Jodal, [9]B. Kaijser, [10]A. Solh-Akerlund, [11]C. Wadsworth [Full author list]Ciba Foundation Symposium [curation]DOI: 10.1002/9780470720288.CH6
PubMed: 346319
1977-04-26
Immunoglobulin and specific-antibody synthesis in vitro by enteral and nonenteral lymphoid tissues after subcutaneous cholera immunization[1]Ann-Mari Svennerholm, [2]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.15.2.360-369.1977
PubMed: 844901
cholera [curation]; antibody [curation]; immunization [curation]1977-02-01
Enterotoxin antibodies in relation to diarrhoea in Swedish soldiers in Cyprus[1]A. M. Svennerholm, [1-Q4981458]Ann-Mari Svennerholm, [2]E. Bäck, [3]Jan Holmgren [Full author list]Bulletin of the World Health Organization [curation]PubMed: 340076Cyprus [curation]; diarrhea [curation]; soldier [curation]1977-01-01
Boosting of Secretory IgA Antibody Responses in Man by Parenteral Cholera Vaccination[1]A. M. Svennerholm, [1-Q4981458]Ann-Mari Svennerholm, [2]Jan Holmgren, [3]L. A. Hanson, [4]B. S. Lindblad, [5]F. Quereshi, [6]R. J. Rahimtoola [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1977.TB00376.X
PubMed: 605366
cholera [curation]; antibody [curation]; immunology [curation]1977-01-01
Enterotoxin-producing bacteria and parasites in stools of Ethiopian children with diarrhoeal disease[1]T. Wadström, [2]A. Aust-Kettis, [3]D. Habte, [4]Jan Holmgren, [5]G. Meeuwisse, [6]R. Möllby, [7]O. Söderlind [Full author list]Archives of Disease in Childhood [curation]DOI: 10.1136/ADC.51.11.865
PubMed: 1008593
Ethiopia [curation]; feces [curation]1976-11-01
Synergistic protective effect in rabbits of immunization with Vibrio cholerae lipopolysaccharide and toxin/toxoid[1]A. M. Svennerholm, [1-Q4981458]Ann-Mari Svennerholm, [2]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.13.3.735-740.1976
PubMed: 1270131
microbiology [curation]; immunology [curation]; Vibrio cholerae [curation]; lipopolysaccharide [curation]; immunization [curation]1976-03-01
Cholera Toxin and the Adenylate Cyclase-Activating Signal[1]Jan Holmgren, [2]I. Lönnroth [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/133.SUPPLEMENT_1.S64
PubMed: 176282
cholera [curation]1976-03-01
Interaction of cholera toxin and toxin derivatives with lymphocytes. II. Modulating effects of cholera toxin on in vivo humoral and cellular immune responses[1]L. Lindholm, [2]Jan Holmgren, [3]S. Lange, [4]I. Lönnroth [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000231560
PubMed: 5378
cholera [curation]; cell-mediated immunity [curation]1976-01-01
Cholera Toxin, Ganglioside Receptors and the Immune Response[1]Jan Holmgren, [2]L. Lindholm [Full author list]Immunological Investigations [curation]DOI: 10.3109/08820137609047617
PubMed: 192668
cholera [curation]; immunology [curation]1976-01-01
Neutralizing antibodies against Escherichia coli and Vibrio cholerae enterotoxins in human milk from a developing country[1]Jan Holmgren, [2]L. A. Hanson, [3]B. Carlson, [4]B. S. Lindblad, [5]J. Rahimtoola [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1976.TB03036.X
PubMed: 790543
Escherichia coli [curation]; Vibrio cholerae [curation]; enterotoxin [curation]; bacterial antibodies [curation]1976-01-01
Antitoxic immunity in experimental cholera: protection, and serum and local antibody responses in rabbits after enteral and parenteral immunization[1]Jan Holmgren, [2]A. M. Svennerholm, [2-Q4981458]Ann-Mari Svennerholm, [3]O. Ouchterlony, [4]A. Anderson, [5]Walletström G, [6]Westerberg-Berndtsson U, [7]G. Walletström [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.12.6.1331-1340.1975
PubMed: 54337
microbiology [curation]; cholera [curation]; antibody [curation]; immunology [curation]; antitoxin [curation]; immunization [curation]1975-12-01
Protein Reagent Modification of Cholera Toxin: Characterization of Effects on Antigenic, Receptor-binding and Toxic Properties[1]Lönnroth I, [2]Jan Holmgren [Full author list]Journal of General Microbiology [curation]DOI: 10.1099/00221287-91-2-263
PubMed: 1206372
microbiology [curation]; cholera [curation]; toxin [curation]1975-12-01
Alteration of the antibody response to Escherichia coli O antigen in mice by prior exposure to various somatic antigens[1]Ahlstedt S, [2]Jan Holmgren [Full author list]Immunology [curation]PubMed: 51829Escherichia coli [curation]1975-09-01
Mechanism of action of cholera toxin. Specific inhibition of toxin-induced activation of adenylate cyclase[1]Jan Holmgren, [2]I. Lönnroth [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(75)80979-3
PubMed: 1079778
cholera [curation]1975-07-15
Interaction of cholera toxin and membrane GM1 ganglioside of small intestine[1]Jan Holmgren, [2]I. Lönnroth, [3]J. Månsson, [4]L. Svennerholm [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.72.7.2520
PubMed: 1058471
cholera [curation]; toxin [curation]; gangliosides [curation]; GM2 (ganglioside) [curation]1975-07-01
Immunological aspects of urinary tract infections[1]Jan Holmgren, [2]Smith JW [Full author list]Progress in Allergy [curation]PubMed: 1098057immunology [curation]1975-01-01
Oligomeric structure of cholera toxin: characteristics of the H and L subunits[1]Jan Holmgren, [2]I. Lonnroth [Full author list]Journal of General Microbiology [curation]DOI: 10.1099/00221287-86-1-49
PubMed: 803547
cholera [curation]1975-01-01
Quantitation of Escherichia coli O antibodies by direct and indirect agglutination in comparison with a radioimmunoassay[1]S. Ahlstedt, [2]U. Jodal, [3]L. A. Hanson, [4]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000231332
PubMed: 804452
Escherichia coli [curation]1975-01-01
Local antibody production in experimental pyelonephritis: amount, avidity, and immunoglobulin class[1]Smith J, [2]Jan Holmgren, [3]Ahlstedt S, [4]Hanson LA [Full author list]Infection and Immunity [curation]PubMed: 4214768pyelonephritis [curation]1974-09-01
Tissue receptor for cholera exotoxin: structural requirements of G11 ganglioside in toxin binding and inactivation[1]Jan Holmgren, [2]Månsson JE, [3]Svennerholm L [Full author list]Medical Biology [curation]PubMed: 4214479cholera [curation]1974-08-01
Chemical and immunological characterisation of the major glucosamine-containing ganglioside of human tissues.[1]Månsson JE, [2]Jan Holmgren, [3]Li YT, [4]Vanier MT, [5]Svennerholm L [Full author list]Medical Biology [curation]PubMed: 4153797immunology [curation]; glucosamine [curation]1974-08-01
Chemical modification of cholera toxin for characterization of antigenic receptor-binding and toxic sites.[1]Lönnroth I, [2]Jan Holmgren [Full author list]FEBS Letters [curation]DOI: 10.1016/0014-5793(74)81158-0
PubMed: 4472031
cholera [curation]1974-08-01
Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding properties and interference with lectin-induced cellular stimulation[1]Jan Holmgren, [2]Lindholm L, [3]Lönnroth I [Full author list]Journal of Experimental Medicine [curation]DOI: 10.1084/JEM.139.4.801
PubMed: 4361243
cholera [curation]; lymphocyte [curation]1974-04-01
Enhancement of the IgG antibody production to Escherichia coli O antigen by prior exposure to serologically different E. coli bacteria[1]Jan Holmgren, [2]Ahlstedt S [Full author list]Immunology [curation]PubMed: 4210595Escherichia coli [curation]1974-01-01
Protective Capacity of Antibodies Against <i>E. coli</i>·Antigen with Special Reference to the Avidity[1]S. Ahlstedt, [2]Jan Holmgren, [3]L. A. Hanson [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000231150
PubMed: 4607906
Escherichia coli [curation]; immunology [curation]; bacterial antibodies [curation]1974-01-01
Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid[1]Jan Holmgren [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.8.6.851-859.1973
PubMed: 4206342
cholera [curation]; Escherichia coli [curation]; Vibrio cholerae [curation]1973-12-01
The validity of the ammonium sulphate precipitation technique of estimation of antibody amount and avidity[1]S. Ahlstedt, [2]Jan Holmgren, [3]L. A. Hanson [Full author list]Immunology [curation]PubMed: 45862861973-12-01
Cross-reactivity between heat labile enterotoxins of Vibrio cholerae and Escherichia coli in neutralization tests in rabbit ileum and skin[1]Jan Holmgren, [2]O. Söderlind, [3]T. Wadström [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]DOI: 10.1111/J.1699-0463.1973.TB02272.X
PubMed: 4592974
Escherichia coli [curation]; Vibrio cholerae [curation]1973-12-01
Tissue receptor for cholera exotoxin: postulated structure from studies with GM1 ganglioside and related glycolipids[1]Jan Holmgren, [2]Lönnroth I, [3]Svennerholm L [Full author list]Infection and Immunity [curation]PubMed: 4125267cholera [curation]1973-08-01
Experimental Studies on Cholera Immunisation: The Protective Immunogenicity in Rabbits of Monomeric and Polymeric Crude Exotoxin[1]Jan Holmgren [Full author list]Journal of Medical Microbiology [curation]DOI: 10.1099/00222615-6-3-363
PubMed: 4726335
microbiology [curation]; cholera [curation]1973-08-01
Immunodiffusion studies of pneumococcal antigens with special reference to serotype 27[1]Broholm KA, [2]Jan Holmgren [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 41497221973-06-01
Subunit structure of cholera toxin[1]Lönnroth I, [2]Jan Holmgren [Full author list]Journal of General Microbiology [curation]DOI: 10.1099/00221287-76-2-417
PubMed: 4198716
cholera [curation]1973-06-01
Enzyme-linked immunosorbent assays for cholera serology[1]Jan Holmgren, [2]Ann-Mari Svennerholm [Full author list]Infection and Immunity [curation]PubMed: 4202959cholera [curation]; ELISEA [curation]1973-05-01
Multiple Attacks of Hepatitis in Drug Addicts: Biochemical, Immunochemical, and Morphologic Characteristics[1]S. Iwarson, [2]P. Lundin, [3]Jan Holmgren, [4]S. Hermodsson [Full author list]Journal of Infectious Diseases [curation]DOI: 10.1093/INFDIS/127.5.544
PubMed: 4698641
1973-05-01
The primary and secondary antibody response to Escherichia coli O6 lipopolysaccharide analysed at the humoral and cellular level. Amount and avidity of the antibodies in relation to protective capacity[1]S. Ahlstedt, [2]Jan Holmgren, [3]L. A. Hanson [Full author list]Immunology [curation]PubMed: 4571425Escherichia coli [curation]; antibody [curation]; lipopolysaccharide [curation]; immunological memory [curation]1973-02-01
The bactericidal effect of normal human serum on E. coli strains from normals and from patients with urinary tract infections[1]S Olling, [2]L A Hanson, [3]Jan Holmgren, [4]U Jodal, [5]K Lincoln, [6]U Lindberg [Full author list]Infection [curation]DOI: 10.1007/BF01638251
PubMed: 4594781
Escherichia coli [curation]1973-01-01
Fixation and inactivation of cholera toxin by GM1 ganglioside[1]Jan Holmgren, [2]I Lönnroth, [3]L Svennerholm [Full author list]Scandinavian Journal of Infectious Diseases [curation]DOI: 10.3109/INF.1973.5.ISSUE-1.15
PubMed: 4199382
cholera [curation]1973-01-01
Asymptomatic bacteriuria--a serious disease?[1]L. A. Hanson, [2]Jan Holmgren, [3]U. Jodal, [4]K. Lincoln, [5]U. Lindberg [Full author list]The BMJ [curation]DOI: 10.1136/BMJ.2.5812.530-A
PubMed: 4555548
engineering [curation]1972-05-27
Experimental studies on cholera immunization. II. Evidence for protective antitoxic immunity mediated by serum antibodies as well as local antibodies[1]Jan Holmgren, [2]Andersson A, [3]Wallerstrom G, [4]Ouchterlony O [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.5.5.662-667.1972
PubMed: 4637602
cholera [curation]; antibody [curation]; immunization [curation]1972-05-01
Significance of amount and avidity of E. coli O antibodies for manifestation of their serological and protective properties. A preliminary study.[1]Ahlstedt S, [2]Jan Holmgren, [3]Hanson LA [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000230661
PubMed: 4558948
Escherichia coli [curation]1972-01-01
An Antigenic Relationship Between Human Kidney, Colon and the Common Antigen of Enterobacteriaceae[1]Jan Holmgren, [2]S. Hammarström, [3]S. E. Holm, [4]J. Ahlmén, [5]P. O. Attman, [6]U. Jodal [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000230824
PubMed: 4631662
immunology [curation]; Enterobacteriaceae [curation]; cross-reactivity [curation]1972-01-01
Experimental studies on cholera immunization. 1. The response of neutralizing and vibriocidal antibodies in rabbits after immunization with culture filtrate material from V. cholerae[1]Jan Holmgren, [2]Svennerholm AM, [2-Q4981458]Ann-Mari Svennerholm, [3]Ouchterlony O [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 4509186cholera [curation]; antibody [curation]; Vibrio cholerae [curation]; immunization [curation]1972-01-01
A radial diffusion agar plaque technique for estimation of the avidity of bactericidal antibodies against Vibrio cholerae.[1]Jan Holmgren, [2]Ann-Mari Svennerholm [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1972.TB03300.X
PubMed: 4129962
Vibrio cholerae [curation]1972-01-01
The Protective Effect against E. coli of O and K Antibodies of Different Immunoglobulin Classes[1]B. Kaijser, [2]Jan Holmgren, [3]L. A. Hanson [Full author list]Scandinavian Journal of Immunology [curation]DOI: 10.1111/J.1365-3083.1972.TB03732.X
PubMed: 4627537
Escherichia coli [curation]; immunology [curation]; bacterial antibodies [curation]1972-01-01
Immunological Cross-Reactivity Between Human Kidney and Certain <i>E. coli</i> and Streptococcal Strains[1]S. E. Holm, [2]Jan Holmgren, [3]J. Ahlmén [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000230821
PubMed: 4631661
Escherichia coli [curation]; immunology [curation]; cross-reactivity [curation]1972-01-01
Immunochemical Studies of Two Cholera Toxin-Containing Standard Culture Filtrate Preparations of Vibrio cholerae[1]Holmgren J, [1-Q5811529]Jan Holmgren, [2]Lönnroth I, [3]Ouchterlony O [Full author list]Infection and Immunity [curation]DOI: 10.1128/IAI.3.6.747-755.1971
PubMed: 16558049
cholera [curation]; Vibrio cholerae [curation]1971-06-01
Quantitation of vibriocidal antibodies using agar plague techniques[1]Jan Holmgren, [2]Svennerholm AM, [2-Q4981458]Ann-Mari Svennerholm, [3]Ouchterlony O [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 50013591971-01-01
Studies on protective effect of O and K antibodies against E. coli bacteria with regard to the immunoglobulin class[1]Kaijser B, [2]Hanson LA, [3]Jan Holmgren, [4]Borssen R [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 4933453Escherichia coli [curation]1971-01-01
An agar plaque method for quantitation of vibriocidal antibodies.[1]Ann-Mari Svennerholm, [2]Jan Holmgren, [3]Ouchterloney O [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 49334561971-01-01
Immunodiffusion studies on pneumococcal antigens with special reference to serotype 27.[1]Broholm KA, [2]Jan Holmgren [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 43975101971-01-01
An antigenic relationship between kidney and certain Escherichia coli strains[1]Jan Holmgren, [2]L A Hanson, [3]S E Holm, [4]B Kauser [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000230540
PubMed: 5000357
Escherichia coli [curation]1971-01-01
Studies of methods for quantitation of agglutinins and precipitins to Escherichia coli O and K antigens[1]Jan Holmgren [Full author list]International Archives of Allergy and Applied Immunology [curation]DOI: 10.1159/000230238
PubMed: 4983343
Escherichia coli [curation]1970-01-01
Comparison of different methods for serial dilution used in serological routine work[1]Kaijser B, [2]Belin L, [3]Hanson LA, [4]Jan Holmgren, [5]Holm SE [Full author list]Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology [curation]PubMed: 49227371970-01-01
Studies of antibodies and immunoglobulin levels in urine from children with urinary tract infections caused by E. coli[1]Jodal U, [2]Hanson A, [3]Jan Holmgren, [4]Kaijser B [Full author list]Acta Paediatrica Scandinavica. Supplement [curation]PubMed: 5277006Escherichia coli [curation]; urinary tract infection [curation]1970-01-01
Precipitating antibodies to E. coli O antigens: a suggested difference in the antibody response of infants and children with first and recurrent attacks of pyelonephritis[1]L. A. Hanson, [2]Jan Holmgren, [3]U. Jodal, [4]J. Winberg [Full author list]Acta Paediatrica Scandinavica [curation]DOI: 10.1111/J.1651-2227.1969.TB04752.X
PubMed: 4983439
Escherichia coli [curation]1969-09-01
Immunodiffusion studies on Escherichia coli. 1. Identification of O, K and H antigens in an O6 strain[1]Jan Holmgren, [2]Eggertsen G, [3]Hanson LA, [4]Lincoln K [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]PubMed: 4984753Escherichia coli [curation]; Immunodiffusion [curation]1969-01-01
Immunodiffusion studies on Escherichia coli. 2. Characterization of antigens used for passive haemagglutination with an O 6 strain as model[1]Jan Holmgren, [2]Hanson LA [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]PubMed: 4911127Escherichia coli [curation]1969-01-01
The antibody response of children with pyelonephritis to different antigens of E. coli[1]Jan Holmgren, [2]Eggertsen G, [3]Hansson LA, [4]Jodal U, [5]Lincoln K, [6]Winberg J [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]PubMed: 4967987Escherichia coli [curation]; pyelonephritis [curation]1968-01-01
The isolation of an oxidase negative strain of Pseudomonas aeruginosa from the urine of a cobalt irradiated patient.[1]Jan Holmgren [Full author list]Acta Pathologica et Microbiologica Scandinavica [curation]DOI: 10.1111/J.1699-0463.1968.TB03224.X
PubMed: 4972314
cobalt [curation]; Pseudomonas aeruginosa [curation]1968-01-01
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