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Jan Paul Medema

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Listed Publications

16 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer[1]Prashanthi Ramesh, [2]Tamsin R M Lannagan, [3]Rene Jackstadt, [4]Lidia Atencia Taboada, [5]Nico Lansu, [6]Pratyaksha Wirapati, [7]Sander R van Hooff, [8]Danielle Dekker, [9]Jessica Pritchard, [10]Aleksandar B Kirov, [11]Sanne M van Neerven, [12]Sabine Tejpar, [13]Geert J P L Kops, [14]Owen J Sansom, [15]Jan Paul Medema [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/S41418-021-00816-W
PubMed: 34117376
2021-06-11
A RAC-GEF network critical for early intestinal tumourigenesis[1]K A Pickering, [2]K Gilroy, [3]J W Cassidy, [4]S K Fey, [5]Arafath Kaja Najumudeen, [6]Lucas B Zeiger, [7]D F Vincent, [8]David M. Gay, [9]J Johansson, [10]R P Fordham, ..., [21]Douglas Strathdee, [22]S R van Hoof, [23]Jan Paul Medema, [24]Kurt Anderson, [25]S M Brachmann, ... [Full author list]Nature Communications [curation]DOI: 10.1038/S41467-020-20255-4
PubMed: 33397922
2021-01-04
Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study[1]I van den Berg, [2]S van de Weerd, [3]J M L Roodhart, [4]G R Vink, [5]R R J Coebergh van den Braak, [6]C R Jimenez, [7]S G Elias, [8]D van Vliet, [9]M Koelink, [10]E Hong, [11]W M U van Grevenstein, [12]M G H van Oijen, [13]R G H Beets-Tan, [14]J H J M van Krieken, [15]J N M IJzermans, [16]Jan Paul Medema, [17]M Koopman, [18]CONNECTION-study group [Full author list]BMC Cancer [curation]DOI: 10.1186/S12885-020-07236-Y
PubMed: 32811457
colon cancer [curation]2020-08-18
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer[1]Maureen Spit, [2]Nicola Fenderico, [3]Ingrid Jordens, [4]Tomasz Radaszkiewicz, [5]Rik Lindeboom, [6]Jeroen M Bugter, [7]Alba Cristobal, [8]Lars Ootes, [9]Max van Osch, [10]Eline Janssen, [11]Kim E Boonekamp, [12]Katerina Hanakova, [13]David Potesil, [14]Zbynek Zdrahal, [15]Sylvia F Boj, [16]Jan Paul Medema, [17]Vítězslav Bryja, [18]Bon-Kyoung Koo, [19]Michiel Vermeulen, [20]Madelon M Maurice [Full author list]The EMBO Journal [curation]DOI: 10.15252/EMBJ.2019103932
PubMed: 32965059
2020-08-10
Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges[1]Joyce Y Buikhuisen, [2]Arezo Torang, [3]Jan Paul Medema [Full author list]Oncogenesis [curation]DOI: 10.1038/S41389-020-00250-6
PubMed: 32647253
colon cancer [curation]2020-07-09
High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1[1]Anne Steins, [2]Madelaine G van Mackelenbergh, [3]Amber P van der Zalm, [4]Remy Klaassen, [5]Bryan Serrels, [6]Sandrine G Goris, [7]Hemant M Kocher, [8]Cynthia Waasdorp, [9]Joan H de Jong, [10]Cansu Tekin, [11]Marc G Besselink, [12]Olivier R Busch, [13]Marc J van de Vijver, [14]Joanne Verheij, [15]Frederike Dijk, [16]Geertjan van Tienhoven, [17]Johanna W Wilmink, [18]Jan Paul Medema, [19]Hanneke Wm van Laarhoven, [20]Maarten F Bijlsma [Full author list]EMBO Reports [curation]DOI: 10.15252/EMBR.201948780
PubMed: 32173982
invasive ductal carcinoma [curation]; pancreatic ductal carcinoma [curation]; pancreatic ductal adenocarcinoma [curation]2020-03-16
Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts[1]Maartje van der Heijden, [2]Daniël M Miedema, [3]Bartłomiej Waclaw, [4]Veronique L Veenstra, [5]Maria C Lecca, [6]Lisanne E Nijman, [7]Erik van Dijk, [8]Sanne M van Neerven, [9]Sophie C Lodestijn, [10]Kristiaan J Lenos, [11]Nina E de Groot, [12]Pramudita R Prasetyanti, [13]Andrea Arricibita Varea, [14]Douglas J Winton, [15]Jan Paul Medema, [16]Edward R Morrissey, [17]Bauke Ylstra, [18]Martin A. Nowak, [19]Maarten F Bijlsma, [20]Louis Vermeulen [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.1813417116
PubMed: 30850544
colorectal cancer [curation]; Cancer stem cells [curation]; xenograft [curation]2019-03-08
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018[1]Lorenzo Galluzzi, [2]Ilio Vitale, [3]Stuart A Aaronson, [4]John M Abrams, [5]Dieter Adam, [6]Patrizia Agostinis, [10]David William Andrews, ..., [102]Seamus J. Martin, [103]Jean-Claude Martinou, [104]Jan Paul Medema, [105]Patrick Mehlen, [106]Pascal Meier, ..., [7]Emad S Alnemri, [8]Lucia Altucci, [9]Ivano Amelio, ... [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/S41418-017-0012-4
PubMed: 29362479
cell death [curation]2018-01-23
Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis[1]M Isabel García-Laorden, [2]Ingrid Stroo, [3]Sanne Terpstra, [4]Sandrine Florquin, [5]Jan Paul Medema, [6]Cornelis van't Veer, [7]Alex F de Vos, [8]Tom van der Poll [Full author list]Mediators of Inflammation [curation]DOI: 10.1155/2017/4137563
PubMed: 28694562
Escherichia coli [curation]; sepsis [curation]2017-06-12
Intra-tumor heterogeneity from a cancer stem cell perspective[1]Pramudita R Prasetyanti, [2]Jan Paul Medema [Full author list]Molecular Cancer [curation]DOI: 10.1186/S12943-017-0600-4
PubMed: 28209166
neoplasm [curation]; neoplastic stem cells [curation]; tumour heterogeneity [curation]2017-02-16
Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia[1]M Isabel García-Laorden, [2]Ingrid Stroo, [3]Dana C Blok, [4]Sandrine Florquin, [5]Jan Paul Medema, [6]Alex F de Vos, [7]Tom van der Poll [Full author list]Journal of Innate Immunity [curation]DOI: 10.1159/000443401
PubMed: 26894590
pneumonia [curation]; Klebsiella pneumoniae [curation]2016-02-20
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)[1]Daniel J. Klionsky, [2]Kotb Abdelmohsen, [3]Akihisa Abe, [4]Md Joynal Abedin, [5]Hagai Abeliovich, [6]Abraham Acevedo-Arozena, [7]Hiroaki Adachi, [8]Christopher M Adams, [9]Peter D Adams, [10]Khosrow Adeli, ..., [1390]Iain A McNeish, [1391]Fatima Mechta-Grigoriou, [1392]Jan Paul Medema, [1393]Diego Luis Medina, [1394]Klara Megyeri, ... [Full author list]Autophagy [curation]DOI: 10.1080/15548627.2015.1100356
PubMed: 26799652
cell biology [curation]; autophagy [curation]2016-01-02
TWE-PRIL; a fusion protein of TWEAK and APRIL[1]Geertruida M. Kolfschoten, [2]Bérengère Pradet-Balade, [3]Michael Hahne, [4]Jan Paul Medema [Full author list]Biochemical Pharmacology [curation]DOI: 10.1016/S0006-2952(03)00493-3
PubMed: 14555217
biochemistry [curation]; pharmacology [curation]2003-10-15
A serine protease is involved in the initiation of DNA damage-induced apoptosis[1]E. C. de Bruin, [2]D. Meersma, [3]J. de Wilde, [4]I. den Otter, [5]E. M. Schipper, [6]Jan Paul Medema, [7]L. T C. Peltenburg [Full author list]Cell Death & Differentiation [curation]DOI: 10.1038/SJ.CDD.4401296
PubMed: 14502243
cell biology [curation]; DNA damage [curation]2003-10-01
Comments on “A Superactive Charcoal for Antidotal Use in Poisonings”[1]Jan Paul Medema [Full author list]Clinical Toxicology [curation]DOI: 10.3109/15563657908988451
PubMed: 436396
charcoal [curation]1979-01-01
Surface areas of elastin samples determined by krypton-85 adsorption[1]L. Robert, [2]B. Robert, [3]Jan Paul Medema, [4]J. P. Houtman [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/0005-2795(70)90092-9
PubMed: 5488945
krypton [curation]1970-07-27
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