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Frank Jessen

Wikidata Item | Scholia Profile [curation] | Reasonator | SQID

Listed Publications

243 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
New insights into the genetic etiology of Alzheimer's disease and related dementias[1]Céline Bellenguez, [2]Fahri Küçükali, [3]Iris E Jansen, [4]Luca Kleineidam, [5]Sonia Moreno-Grau, [6]Najaf Amin, [7]Adam C Naj, [8]Rafael Campos, [9]Benjamin Grenier-Boley, [10]Victor Andrade, ..., [387]Perminder Sachdev, [388]Karen Mather, [389]Frank Jessen, [390]M Arfan Ikram, [391]Alexandre de Mendonça, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/S41588-022-01024-Z
PubMed: 35379992
2022-04-01
A microRNA signature that correlates with cognition and is a target against cognitive decline[1]Md Rezaul Islam, [2]Lalit Kaurani, [3]Tea Berulava, [4]Urs Heilbronner, [5]Monika Budde, [6]Tonatiuh Pena Centeno, [7]Vakthang Elerdashvili, [8]Maria-Patapia Zafeiriou, [9]Eva Benito, [10]Sinem M Sertel, ..., [43]Jens Wiltfang, [44]Emrah Düzel, [45]Frank Jessen, [46]Delcode Study Group, [47]Silvio O. Rizzoli, ... [Full author list]EMBO Molecular Medicine [curation]DOI: 10.15252/EMMM.202013659
PubMed: 34633146
2021-10-11
Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes[1]Boris-Stephan Rauchmann, [2]Ersin Ersoezlue, [3]Sophia Stoecklein, [4]Daniel Keeser, [5]Frederic Brosseron, [6]Katharina Buerger, [7]Peter Dechent, [8]Laura Dobisch, [9]Birgit Ertl-Wagner, [10]Klaus Fliessbach, ..., [33]Renat Yakupov, [34]Emrah Duezel, [35]Frank Jessen, [36]Robert Perneczky, [37]DELCODE study group and the Alzheimer's Disease Neuroimaging Initiative (ADNI) [Full author list]Cerebral Cortex [curation]DOI: 10.1093/CERCOR/BHAB130
PubMed: 34080613
2021-10-01
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores[1]Itziar De Rojas, [2]Sonia Moreno-Grau, [3]Niccolo Tesi, [4]Benjamin Grenier-Boley, [5]Victor Andrade, [6]Iris E Jansen, [7]Nancy Pedersen, [8]Najada Stringa, [9]Anna Zettergren, [10]Isabel Hernández, ..., [107]Florentino Sanchez-Garcia, [108]Francesca Mangialasche, [109]Frank Jessen, [110]Gaël Nicolas, [111]Geir Selbæk, ... [Full author list]Nature Communications [curation]DOI: 10.1038/S41467-021-22491-8
PubMed: 34099642
2021-06-07
Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study[1]Susanne Roehr, [2]Alexander Pabst, [3]Steffi G. Riedel-Heller, [4]Frank Jessen, [5]Yuda Turana, [6]Yvonne S Handajani, [7]Carol Brayne, [8]Fiona E Matthews, [9]Blossom C M Stephan, [10]Richard B. Lipton, ... [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-020-00734-Y
PubMed: 33339532
2020-12-18
Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer's disease spectrum[1]Chimezie O Amaefule, [2]Martin Dyrba, [3]Steffen Wolfsgruber, [4]Alexandra Polcher, [5]Anja Schneider, [6]Klaus Fliessbach, [7]Annika Spottke, [8]Dix Meiberth, [9]Lukas Preis, [10]Oliver Peters, ..., [30]Coraline D Metzger, [31]Michael Wagner, [32]Frank Jessen, [33]Stefan J Teipel [Full author list]NeuroImage: Clinical [curation]DOI: 10.1016/J.NICL.2020.102533
PubMed: 33360018
2020-12-17
Abnormal Regional and Global Connectivity Measures in Subjective Cognitive Decline Depending on Cerebral Amyloid Status[1]Shumei Li, [2]Marcel Daamen, [3]Lukas Scheef, [4]Florian C Gaertner, [5]Ralph Buchert, [6]Martina Buchmann, [7]Katharina Buerger, [8]Cihan Catak, [9]Laura Dobisch, [10]Alexander Drzezga, ..., [33]Steffen Wolfsgruber, [34]Emrah Düzel, [35]Frank Jessen, [36]Oliver Peters, [37]Henning Boecker, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-200472
PubMed: 33337359
2020-12-10
Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum[1]Meret Herdick, [2]Martin Dyrba, [3]Hans-Christian J Fritz, [4]Slawek Altenstein, [5]Tommaso Ballarini, [6]Frederic Brosseron, [7]Katharina Buerger, [8]Arda Can Cetindag, [9]Peter Dechent, [10]Laura Dobisch, ..., [32]Ruth Vukovich, [33]Jens Wiltfang, [34]Frank Jessen, [35]Stefan Teipel, [36]Michel J Grothe [Full author list]NeuroImage: Clinical [curation]DOI: 10.1016/J.NICL.2020.102495
PubMed: 33395986
2020-11-11
Prediction of dementia of Alzheimer type by different types of subjective cognitive decline[1]Frank Jessen, [2]Luca Kleineidam, [3]Steffen Wolfsgruber, [4]Horst Bickel, [5]Christian Brettschneider, [6]Angela Fuchs, [7]Hanna Kaduszkiewicz, [8]Hans-Helmut König, [9]Tina Mallon, [10]Silke Mamone, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1002/ALZ.12163
PubMed: 33140565
2020-11-02
Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy[1]Matthias Brendel, [2]Henryk Barthel, [3]Thilo van Eimeren, [4]Ken Marek, [5]Leonie Beyer, [6]Mengmeng Song, [7]Carla Palleis, [8]Mona Gehmeyr, [9]Urban M Fietzek, [10]Gesine Respondek, ..., [15]Michael T Barbe, [16]Oezguer Onur, [17]Frank Jessen, [18]Dorothee Saur, [19]Matthias L Schroeter, ... [Full author list]JAMA Neurology [curation]DOI: 10.1001/JAMANEUROL.2020.2526
PubMed: 33165511
biomarker [curation]; progressive supranuclear palsy [curation]2020-11-01
Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study[1]Lena Sannemann, [2]Ann-Katrin Schild, [3]Slawek Altenstein, [4]Claudia Bartels, [5]Frederic Brosseron, [6]Katharina Buerger, [7]Nicoleta Carmen Cosma, [8]Klaus Fliessbach, [9]Silka Dawn Freiesleben, [10]Wenzel Glanz, ..., [32]Steffen Wolfsgruber, [33]Emrah Duezel, [34]Frank Jessen, [35]DELCODE Study Group [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-020-00701-7
PubMed: 33066827
biomarker [curation]2020-10-16
Evaluation of evidence grades in psychiatry and psychotherapy guidelines[1]Lisa Löhrs, [2]Mirjam Handrack, [3]Ina Kopp, [4]Frank Jessen, [5]Elias Wagner, [6]Peter Falkai, [7]Astrid Röh, [8]Wolfgang Strube, [9]Alkomiet Hasan [Full author list]BMC Psychiatry [curation]DOI: 10.1186/S12888-020-02897-2
PubMed: 33046040
2020-10-12
[Memory clinics in Germany-structural requirements and areas of responsibility][1]Lucrezia Hausner, [2]Lutz Frölich, [3]Christine A F von Arnim, [4]Jens Bohlken, [5]Richard Dodel, [6]Markus Otto, [7]Michael Rapp, [8]Jörg Schulz, [9]Tilmann Supprian, [10]M Axel Wollmer, [11]Frank Jessen, [12]Deutsches Netzwerk Gedächtnisambulanzen [Full author list]Der Nervenarzt [curation]DOI: 10.1007/S00115-020-01007-7
PubMed: 33025072
2020-10-06
Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid binding protein 3 and ferritin to neurodegeneration and neuroinflammation[1]Frederic Brosseron, [2]Kilian Kleemann, [3]Carl-Christian Kolbe, [4]Francesco Santarelli, [5]Sergio Castro-Gomez, [6]Pawel Tacik, [7]Eicke Latz, [8]Frank Jessen, [9]Michael T Heneka [Full author list]Journal of Neurochemistry [curation]DOI: 10.1111/JNC.15175
PubMed: 32894885
biomarker [curation]2020-09-07
Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies[1]Giovanni B Frisoni, [2]José Luis Molinuevo, [3]Daniele Altomare, [4]Emmanuel Carrera, [5]Frederik Barkhof, [6]Johannes Berkhof, [7]Julien Delrieu, [8]Bruno Dubois, [9]Miia Kivipelto, [10]Agneta Nordberg, [11]Jonathan M Schott, [12]Wiesje M van der Flier, [13]Bruno Vellas, [14]Frank Jessen, [15]Philip Scheltens, [16]Craig Ritchie [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1002/ALZ.12132
PubMed: 32815289
2020-08-20
Minor neuropsychological deficits in patients with subjective cognitive decline[1]Steffen Wolfsgruber, [2]Luca Kleineidam, [3]Jannis Guski, [4]Alexandra Polcher, [5]Ingo Frommann, [6]Sandra Roeske, [7]Eike Jakob Spruth, [8]Christiana Franke, [9]Josef Priller, [10]Ingo Kilimann, ..., [31]Frederic Brosseron, [32]Dix Meiberth, [33]Frank Jessen, [34]Michael Wagner, [35]DELCODE study group [Full author list]Neurology [curation]DOI: 10.1212/WNL.0000000000010142
PubMed: 32636322
2020-07-07
One stop shop: Flortaucipir PET differentiates amyloid positive and negative forms of neurodegenerative diseases[1]Jochen Hammes, [2]Gerard N Bischof, [3]Karl P Bohn, [4]Ozgur Onur, [5]Anja Schneider, [6]Klaus Fliessbach, [7]Merle C Hoenig, [8]Frank Jessen, [9]Bernd Neumaier, [10]Alexander E Drzezga, [11]Thilo van Eimeren [Full author list]The Journal of Nuclear Medicine [curation]DOI: 10.2967/JNUMED.120.244061
PubMed: 32620704
2020-07-03
Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer's Disease via Lead-Lag Analysis[1]Manuel Fuentes, [2]Arne Klostermann, [3]Luca Kleineidam, [4]Chris Bauer, [5]Johannes Schuchhardt, [6]Wolfgang Maier, [7]Frank Jessen, [8]Lutz Frölich, [9]Jens Wiltfang, [10]Johannes Kornhuber, [11]Stefan Klöppel, [12]Vera Schieting, [13]Stefan J Teipel, [14]Michael Wagner, [15]Oliver Peters [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-200230
PubMed: 32597807
2020-06-24
Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly[1]Cosima Rhein, [2]Christiane Mühle, [3]Bernd Lenz, [4]Tanja Richter-Schmidinger, [5]Georgios Kogias, [6]Fernando Boix, [7]Anbarasu Lourdusamy, [8]Arnd Dörfler, [9]Oliver Peters, [10]Alfredo Ramirez, [11]Frank Jessen, [12]Wolfgang Maier, [13]Michael Hüll, [14]Lutz Frölich, [15]Stefan Teipel, [16]Jens Wiltfang, [17]Johannes Kornhuber, [18]Christian P Müller [Full author list]Brain Research Bulletin [curation]DOI: 10.1016/J.BRAINRESBULL.2020.05.001
PubMed: 32418901
2020-05-11
Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial[1]Franziska Maier, [2]Annika Spottke, [3]Jan-Philipp Bach, [4]Claudia Bartels, [5]Katharina Buerger, [6]Richard Dodel, [7]Andreas Fellgiebel, [8]Klaus Fliessbach, [9]Lutz Frölich, [10]Lucrezia Hausner, ..., [22]Christine A F von Arnim, [23]Jens Wiltfang, [24]Frank Jessen [Full author list]JAMA Network Open [curation]DOI: 10.1001/JAMANETWORKOPEN.2020.6027
PubMed: 32463470
2020-05-01
Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury[1]Leonie Beyer, [2]Alexander Nitschmann, [3]Henryk Barthel, [4]Thilo van Eimeren, [5]Marcus Unterrainer, [6]Julia Sauerbeck, [7]Ken Marek, [8]Mengmeng Song, [9]Carla Palleis, [10]Gesine Respondek, ..., [12]Michael T Barbe, [13]Özgür Onur, [14]Frank Jessen, [15]Dorothee Saur, [16]Matthias L Schroeter, ... [Full author list]European Journal of Nuclear Medicine and Molecular Imaging [curation]DOI: 10.1007/S00259-020-04788-W
PubMed: 32318783
2020-04-21
Quantitative amyloid PET in Alzheimer's disease: the AMYPAD prognostic and natural history study[1]Isadora Lopes Alves, [2]Lyduine E Collij, [3]Daniele Altomare, [4]Giovanni B Frisoni, [5]Laure Saint-Aubert, [6]Pierre Payoux, [7]Miia Kivipelto, [8]Frank Jessen, [9]Alexander Drzezga, [10]Annebet Leeuwis, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1002/ALZ.12069
PubMed: 32281303
2020-04-12
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment[1]Luca Kleineidam, [2]Vincent Chouraki, [3]Tomasz Próchnicki, [4]Sven J van der Lee, [5]Laura Madrid-Márquez, [6]Holger Wagner-Thelen, [7]Ilker Karaca, [8]Leonie Weinhold, [9]Steffen Wolfsgruber, [10]Anne Boland, ..., [42]Michael T Heneka, [43]Philippe Amouyel, [44]Frank Jessen, [45]Merce Boada, [46]Wolfgang Maier, ... [Full author list]Acta Neuropathologica [curation]DOI: 10.1007/S00401-020-02138-6
PubMed: 32166339
mild cognitive impairment [curation]; cognitive dysfunction [curation]2020-03-12
Cognitive behavioural therapy for the treatment of late life depression: study protocol of a multicentre, randomized, observer-blinded, controlled trial (CBTlate)[1]Forugh S Dafsari, [2]Bettina Bewernick, [3]Matthias Biewer, [4]Hildegard Christ, [5]Katharina Domschke, [6]Lutz Froelich, [7]Martin Hellmich, [8]Melanie Luppa, [9]Oliver Peters, [10]Alfredo Ramirez, [11]Steffi G. Riedel-Heller, [12]Elisabeth Schramm, [13]Magnus-Sebastian Vry, [14]Michael Wagner, [15]Martin Hautzinger, [16]Frank Jessen [Full author list]BMC Psychiatry [curation]DOI: 10.1186/S12888-019-2412-0
PubMed: 31881995
late life depression [curation]; multicenter clinical trial [curation]; study protocol [curation]2019-12-27
Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels[1]Matthew J Betts, [2]Arturo Cardenas-Blanco, [3]Martin Kanowski, [4]Annika Spottke, [5]Stefan J Teipel, [6]Ingo Kilimann, [7]Frank Jessen, [8]Emrah Düzel [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2019.02.001
PubMed: 30976648
Alzheimer's disease [curation]; dementia [curation]2019-12-01
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood[1]Roy Lardenoije, [2]Janou A Y Roubroeks, [3]Ehsan Pishva, [4]Markus Leber, [5]Holger Wagner, [6]Artemis Iatrou, [7]Adam R Smith, [8]Rebecca G Smith, [9]Lars Eijssen, [10]Luca Kleineidam, ..., [13]Tobias Luck, [14]Steffi G. Riedel-Heller, [15]Frank Jessen, [16]Wolfgang Maier, [17]Michael Wagner, ... [Full author list]Clinical Epigenetics [curation]DOI: 10.1186/S13148-019-0755-5
PubMed: 31775875
2019-11-27
Refining the understanding of typical Alzheimer disease[1]Frank Jessen [Full author list]Nature Reviews Neurology [curation]DOI: 10.1038/S41582-019-0259-0
PubMed: 31506592
2019-11-01
Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults[1]David Berron, [2]Arturo Cardenas-Blanco, [3]Daniel Bittner, [4]Coraline D Metzger, [5]Annika Spottke, [6]Michael T Heneka, [7]Klaus Fliessbach, [8]Anja Schneider, [9]Stefan J Teipel, [10]Michael Wagner, [11]Oliver Speck, [12]Frank Jessen, [13]Emrah Düzel [Full author list]Journal of Neuroscience [curation]DOI: 10.1523/JNEUROSCI.1279-19.2019
PubMed: 31541019
mnemonic [curation]2019-09-20
A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2[1]Meliha Karsak, [2]Konstantin Glebov, [3]Marina Scheffold, [4]Thomas Bajaj, [5]Amit Kawalia, [6]Ilker Karaca, [7]Sebastian Rading, [8]Johannes Kornhuber, [9]Oliver Peters, ..., [20]Holger Thiele, [21]Martina Lennarz, [22]Frank Jessen, [23]Wolfgang Maier, [24]Christian Kubisch, ... [Full author list]Human Mutation [curation]DOI: 10.1002/HUMU.23904
PubMed: 31464095
heterozygosity [curation]2019-09-15
Promoting stigma coping and empowerment in patients with schizophrenia and depression: results of a cluster-RCT[1]Wolfgang Gaebel, [2]Harald Zäske, [3]Klaus Hesse, [4]Stefan Klingberg, [5]Christian Ohmann, [6]Jürgen Grebe, [7]Henrike Kolbe, [8]Andrea Icks, [9]Frank Schneider, [10]Volker Backes, ..., [15]Maria-Christiane Jockers-Scherübl, [16]Timo Krüger, [17]Frank Jessen, [18]Andreas Bechdolf, [19]Tilo Kircher, ... [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-019-01064-3
PubMed: 31520149
schizophrenia [curation]2019-09-13
Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment[1]Wilma A Bainbridge, [2]David Berron, [3]Hartmut Schütze, [4]Arturo Cardenas-Blanco, [5]Coraline Metzger, [6]Laura Dobisch, [7]Daniel Bittner, [8]Wenzel Glanz, [9]Annika Spottke, [10]Janna Rudolph, ..., [30]Steffen Wolfsgruber, [31]Michael Wagner, [32]Frank Jessen, [33]Chris Baker, [34]Emrah Düzel [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2019.07.005
PubMed: 31517023
mild cognitive impairment [curation]; cognitive dysfunction [curation]2019-09-05
Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing[1]Brian W Kunkle, [2]Benjamin Grenier-Boley, [3]Rebecca C Sims, [4]Joshua C Bis, [5]Vincent Damotte, [6]Adam C Naj, [7]Anne Boland, [8]Maria Vronskaya, [9]Sven J van der Lee, [10]Alexandre Amlie-Wolf, ..., [285]Jeffrey Kaye, [286]Kim Oates, [287]Frank Jessen, [288]Neil Kowall, [289]Bruno Vellas, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/S41588-019-0495-7
PubMed: 31417202
2019-09-01
Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study[1]Lisa Miebach, [2]Steffen Wolfsgruber, [3]Alexandra Polcher, [4]Oliver Peters, [5]Felix Menne, [6]Katja Luther, [7]Enise Incesoy, [8]Josef Priller, [9]Eike Spruth, [10]Slawek Altenstein, ..., [32]Dix Meiberth, [33]Alfredo Ramirez, [34]Frank Jessen, [35]Michael Wagner [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-019-0515-Y
PubMed: 31366409
2019-07-31
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease[1]Emily Baker, [2]Rebecca Sims, [3]Ganna Leonenko, [4]Aura Frizzati, [5]Janet C Harwood, [6]Detelina Grozeva, [7]GERAD/PERADES, [8]CHARGE, [9]ADGC, [10]EADI, ..., [23]Wolfgang Maier, [24]Reinhard Heun, [25]Frank Jessen, [26]Oliver Peters, [27]Martin Dichgans, ... [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0218111
PubMed: 31283791
2019-07-08
Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease based on multicenter diffusion tensor imaging[1]Katharina Brueggen, [2]Martin Dyrba, [3]Arturo Cardenas-Blanco, [4]Anja Schneider, [5]Klaus Fliessbach, [6]Katharina Buerger, [7]Daniel Janowitz, [8]Oliver Peters, [9]Felix Menne, [10]Josef Priller, ..., [22]Laura Dobisch, [23]Emrah Düzel, [24]Frank Jessen, [25]Stefan J Teipel, [26]DELCODE Study Group [Full author list]Journal of Neurology [curation]DOI: 10.1007/S00415-019-09429-3
PubMed: 31227891
mild cognitive impairment [curation]; diffusion tensor imaging [curation]; cognitive dysfunction [curation]2019-06-21
Level of education mitigates the impact of tau pathology on neuronal function[1]Merle C Hoenig, [2]Gérard N Bischof, [3]Özgür A Onur, [4]Juraj Kukolja, [5]Frank Jessen, [6]Klaus Fliessbach, [7]Bernd Neumaier, [8]Gereon Rudolf Fink, [9]Elke Kalbe, [10]Alexander Drzezga, [11]Thilo van Eimeren, [12]Alzheimer's Disease Neuroimaging Initiative [Full author list]European Journal of Nuclear Medicine and Molecular Imaging [curation]DOI: 10.1007/S00259-019-04342-3
PubMed: 31183635
2019-06-10
The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community[1]Octavio Rodríguez-Gómez, [2]Adrián Rodrigo, [3]Fátima Iradier, [4]Miguel A Santos-Santos, [5]Hans Hundemer, [6]Andreea Ciudin, [7]Lena Sannemann, [8]Marissa Zwan, [9]Bridget Glaysher, [10]Anders Wimo, ..., [33]Annette Dumas, [34]Jean Georges, [35]Frank Jessen, [36]Bengt Winblad, [37]Craig Shering, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2019.02.003
PubMed: 31076376
2019-05-07
Personalized risk for clinical progression in cognitively normal subjects-the ABIDE project[1]Ingrid S van Maurik, [2]Rosalinde E R Slot, [3]Sander C J Verfaillie, [4]Marissa D Zwan, [5]Femke Bouwman, [6]Niels D Prins, [7]Charlotte Teunissen, [8]Philip Scheltens, [9]Frederik Barkhof, [10]Mike P. Wattjes, [11]José Luis Molinuevo, [12]Lorena Rami, [13]Steffen Wolfsgruber, [14]Olive Melissa Minor Peters, [15]Frank Jessen, [16]Johannes Berkhof, [17]Wiesje van der Flier [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-019-0487-Y
PubMed: 30987684
cerebrospinal fluid [curation]2019-04-16
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease[1]Nicolai Franzmeier, [2]Jinyi Ren, [3]Alexander Damm, [4]Gemma C Monté-Rubio, [5]Mercè Boada, [6]Agustín Ruíz, [7]Alfredo Ramirez, [8]Frank Jessen, [9]Emrah Düzel, [10]Octavio Rodríguez Gómez, ... [Full author list]Molecular Psychiatry [curation]DOI: 10.1038/S41380-019-0404-6
PubMed: 30899092
2019-03-21
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing[1]Brian W Kunkle, [2]Benjamin Grenier-Boley, [3]Rebecca C Sims, [4]Joshua C Bis, [5]Vincent Damotte, [6]Adam C Naj, [7]Anne Boland, [8]Maria Vronskaya, [9]Sven J van der Lee, [10]Alexandre Amlie-Wolf, ..., [285]Jeffrey Kaye, [286]Kim Oates, [287]Frank Jessen, [288]Neil Kowall, [289]Bruno Vellas, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/S41588-019-0358-2
PubMed: 30820047
2019-02-28
Stress and Alzheimer's disease[1]Claus M Escher, [2]Lena Sannemann, [3]Frank Jessen [Full author list]Journal of Neural Transmission [curation]DOI: 10.1007/S00702-019-01988-Z
PubMed: 30788601
Alzheimer's disease [curation]2019-02-20
Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease[1]Maria Carolina Dalmasso, [2]Luis Ignacio Brusco, [3]Natividad Olivar, [4]Carolina Muchnik, [5]Claudia Hanses, [6]Esther Milz, [7]Julian Becker, [8]Stefanie Heilmann-Heimbach, [9]Per Hoffmann, [10]Federico A Prestia, ..., [48]Horacio Scaro, [49]Wolfgang Maier, [50]Frank Jessen, [51]Carlos Alberto Mangone, [52]Jean-Charles Lambert, ... [Full author list]Translational Psychiatry [curation]DOI: 10.1038/S41398-019-0394-9
PubMed: 30705288
2019-01-31
Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples[1]Steffen Wolfsgruber, [2]José Luis Molinuevo, [3]Michael Wagner, [4]Charlotte Teunissen, [5]Lorena Rami, [6]Nina Coll-Padrós, [7]Femke H Bouwman, [8]Rosalinde E R Slot, [9]Linda M P Wesselman, [10]Oliver Peters, ..., [21]Sietske A M Sikkes, [22]Wiesje M van der Flier, [23]Frank Jessen [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-018-0463-Y
PubMed: 30654834
Alzheimer's disease [curation]; biomarker [curation]2019-01-17
Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness[1]Stefan J Teipel, [2]Jan O Kuper-Smith, [3]Claudia Bartels, [4]Frederic Brosseron, [5]Martina Buchmann, [6]Katharina Buerger, [7]Cihan Catak, [8]Daniel Janowitz, [9]Peter Dechent, [10]Laura Dobisch, ..., [29]Steffen Wolfsgruber, [30]Emrah Düzel, [31]Frank Jessen, [32]Martin Dyrba, [33]DELCODE study group [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-190446
PubMed: 31594223
2019-01-01
"Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia"[1]William J. Jagust, [2]Clifford Jack, [3]David A Bennett, [4]Kaj Blennow, [5]Samantha Budd Haeberlein, [6]David M. Holtzman, [7]Frank Jessen, [8]Jason Karlawish, [9]Enchi Liu, [10]Jose Luis Molinuevo, [11]Thomas Montine, [12]Creighton Phelps, [13]Katherine P Rankin, [14]Christopher C Rowe, [15]Philip Scheltens, [16]Eric Siemers, [17]Reisa Sperling [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2018.11.002
PubMed: 30642435
2019-01-01
The SCD-Well randomized controlled trial: Effects of a mindfulness-based intervention versus health education on mental health in patients with subjective cognitive decline (SCD)[1]Natalie L Marchant, [2]Thorsten Barnhofer, [3]Olga M Klimecki, [4]Géraldine Poisnel, [5]Antoine Lutz, [6]Eider Arenaza-Urquijo, [7]Fabienne Collette, [8]Miranka Wirth, [9]Ann-Katrin Schild, [10]Nina Coll-Padrós, [11]Leslie Reyrolle, [12]Deborah Horney, [13]Pierre Krolak-Salmon, [14]José Luis Molinuevo, [15]Zuzana Walker, [16]Aline Maillard, [17]Eric Frison, [18]Frank Jessen, [19]Gael Chételat, [20]SCD-WELL Medit-Ageing Research Group [Full author list]Alzheimer's & dementia (New York, N. Y.) [curation]DOI: 10.1016/J.TRCI.2018.10.010
PubMed: 30581979
mental health [curation]2018-12-14
Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia[1]Rosalinde E R Slot, [2]Sietske Sikkes, [3]Johannes Berkhof, [4]Henry Brodaty, [5]Rachel F Buckley, [6]Enrica Cavedo, [7]Efthimios Dardiotis, [8]Francoise Guillo-Benarous, [9]Harald Hampel, [10]Nicole A Kochan, ..., [28]Michael Wagner, [29]Steffen Wolfsgruber, [30]Frank Jessen, [31]Alzheimer's Disease Neuroimaging Initiative, [32]DESCRIPA working group, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2018.10.003
PubMed: 30555032
Alzheimer's disease [curation]2018-12-13
Subregional volume reduction of the cholinergic forebrain in subjective cognitive decline (SCD)[1]Lukas Scheef, [2]Michel J. Grothe, [3]Alexander Koppara, [4]Marcel Daamen, [5]Henning Boecker, [6]Hans Biersack, [7]Hans H Schild, [8]Michael Wagner, [9]Stefan Teipel, [10]Frank Jessen [Full author list]NeuroImage: Clinical [curation]DOI: 10.1016/J.NICL.2018.101612
PubMed: 30555006
2018-11-27
Is function in instrumental activities of daily living a useful feature in predicting Alzheimer's disease dementia in subjective cognitive decline?[1]Susanne Roehr, [2]Steffi G. Riedel-Heller, [3]Hanna Kaduszkiewicz, [4]Michael Wagner, [5]Angela Fuchs, [6]Carolin van der Leeden, [7]Birgitt Wiese, [8]Jochen Werle, [9]Horst Bickel, [10]Hans-Helmut Koenig, [11]Steffen Wolfsgruber, [12]Michael Pentzek, [13]Dagmar Weeg, [14]Silke Mamone, [15]Siegfried Weyerer, [16]Christian Brettschneider, [17]Wolfgang Maier, [18]Martin Scherer, [19]Frank Jessen, [20]Tobias Luck [Full author list]International Journal of Geriatric Psychiatry [curation]DOI: 10.1002/GPS.5010
PubMed: 30353573
Alzheimer's disease [curation]; dementia [curation]2018-11-09
CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume[1]Emrah Düzel, [2]David Berron, [3]Hartmut Schütze, [4]Arturo Cardenas-Blanco, [5]Coraline Metzger, [6]Matthew Betts, [7]Gabriel Ziegler, [8]Yi Chen, [9]Laura Dobisch, [10]Daniel Bittner, ..., [38]Steffen Wolfsgruber, [39]Michael Wagner, [40]Frank Jessen [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2018.10.003
PubMed: 30555890
2018-11-02
Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes[1]Ana Espinosa, [2]Begoña Hernández-Olasagarre, [3]Sonia Moreno-Grau, [4]Luca Kleineidam, [5]Stefanie Heilmann-Heimbach, [6]Isabel Hernández, [7]Steffen Wolfsgruber, [8]Holger Wagner, [9]Maitée Rosende-Roca, [10]Ana Mauleón, ..., [40]Markus M Nöthen, [41]Michael Wagner, [42]Frank Jessen, [43]Lluis Tárraga, [44]Mercè Boada, ... [Full author list]Frontiers in Aging Neuroscience [curation]DOI: 10.3389/FNAGI.2018.00340
PubMed: 30425636
mild cognitive impairment [curation]; endophenotype [curation]; Ageing [curation]; cognitive dysfunction [curation]2018-10-30
AMYPAD Diagnostic and Patient Management Study: Rationale and design[1]Giovanni B Frisoni, [2]Frederik Barkhof, [3]Daniele Altomare, [4]Johannes Berkhof, [5]Marina Boccardi, [6]Elisa Canzoneri, [7]Lyduine Collij, [8]Alexander Drzezga, [9]Gill Farrar, [10]Valentina Garibotto, [11]Rossella Gismondi, [12]Juan-Domingo Gispert, [13]Frank Jessen, [14]Miia Kivipelto, [15]Isadora Lopes Alves, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2018.09.003
PubMed: 30339801
patient [curation]; diagnosis [curation]2018-10-16
Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies[1]Xiaochen Hu, [2]Charlotte Teunissen, [3]Annika Spottke, [4]Michael T Heneka, [5]Emrah Düzel, [6]Olive Melissa Minor Peters, [7]Siyao Li, [8]Josef Priller, [9]Katharina Buerger, [10]Stefan J Teipel, [11]Christoph Laske, [12]Sander C J Verfaillie, [13]Frederik Barkhof, [14]Nina Coll-Padrós, [15]Lorena Rami, [16]José Luis Molinuevo, [17]Wiesje van der Flier, [18]Frank Jessen [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2018.09.002
PubMed: 30321506
biomarker [curation]2018-10-12
Computer-assisted prediction of clinical progression in the earliest stages of AD[1]Hanneke F M Rhodius-Meester, [2]Hilkka Liedes, [3]Juha R Koikkalainen, [4]Steffen Wolfsgruber, [5]Nina Coll-Padrós, [6]Johannes Kornhuber, [7]Olive Melissa Minor Peters, [8]Frank Jessen, [9]Luca Kleineidam, [10]José Luis Molinuevo, ... [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2018.09.001
PubMed: 30619929
2018-10-08
Informal caregivers' perspectives on health of and (potentially inappropriate) medication for (relatively) independent oldest-old people - a qualitative interview study[1]Nadine Pohontsch, [2]Antje Löffler, [3]Tobias Luck, [4]Kathrin Heser, [5]Debora Parker, [6]Britta Haenisch, [7]Steffi G. Riedel-Heller, [8]Frank Jessen, [9]Martin Scherer [Full author list]BMC Geriatrics [curation]DOI: 10.1186/S12877-018-0849-5
PubMed: 30045689
2018-07-25
Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly[1]Karina Fischer, [2]Debora Melo van Lent, [3]Steffen Wolfsgruber, [4]Leonie Weinhold, [5]Luca Kleineidam, [6]Horst Bickel, [7]Martin Scherer, [8]Marion Eisele, [9]Hendrik van den Bussche, [10]Birgitt Wiese, [11]Hans-Helmut König, [12]Siegfried Weyerer, [13]Michael Pentzek, [14]Susanne Roehr, [15]Wolfgang Maier, [16]Frank Jessen, [17]Matthias Schmid, [18]Steffi G. Riedel-Heller, [19]Michael Wagner [Full author list]Nutrients [curation]DOI: 10.3390/NU10070852
PubMed: 29966314
dementia [curation]2018-06-29
Advance directives for future dementia can be modified by a brief video presentation on dementia care: An experimental study[1]Theresia Volhard, [2]Frank Jessen, [3]Luca Kleineidam, [4]Steffen Wolfsgruber, [5]Dirk Lanzerath, [6]Michael Wagner, [7]Wolfgang Maier [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0197229
PubMed: 29795605
dementia [curation]2018-05-24
Wishes and preferences for an online lifestyle program for brain health-A mixed methods study[1]Linda M P Wesselman, [2]Ann-Katrin Schild, [3]Nina Coll-Padrós, [4]Wieke E van der Borg, [5]Judith H P Meurs, [6]Astrid M Hooghiemstra, [7]Rosalinde E R Slot, [8]Lena Sannemann, [9]Lorena Rami, [10]José Luis Molinuevo, [11]Femke H Bouwman, [12]Frank Jessen, [13]Wiesje van der Flier, [14]Sietske A M Sikkes, [15]Euro-SCD working group [Full author list]Alzheimer's & dementia (New York, N. Y.) [curation]DOI: 10.1016/J.TRCI.2018.03.003
PubMed: 29955658
2018-04-09
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.[2]Emrah Düzel, [3]Frank Jessen, [4]Katharina Buerger, [6]Marco Duering, [7]Martin Dichgans, [8]Christian Haass, [9]Marc Suárez-Calvet, [10]Anne M Fagan, ... [Full author list]Brain [curation]DOI: 10.1093/BRAIN/AWY008
PubMed: 29462334
cognitive dysfunction [curation]2018-04-01
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.[1]Clifford Jack, [2]David A Bennett, [3]Kaj Blennow, [4]Maria C Carrillo, [5]Billy Dunn, [6]Samantha Budd Haeberlein, [7]David M. Holtzman, [8]William J. Jagust, [9]Frank Jessen, [10]Jason Karlawish, [11]Enchi Liu, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2018.02.018
PubMed: 29653606
2018-04-01
One step towards dementia prevention[1]Giovanni B Frisoni, [2]Frank Jessen [Full author list]Lancet Neurology [curation]DOI: 10.1016/S1474-4422(18)30086-3
PubMed: 29500155
dementia [curation]2018-02-27
Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease.[1]Frederic Brosseron, [2]Andreas Traschütz, [3]Catherine N Widmann, [4]Markus P Kummer, [5]Pawel Tacik, [6]Francesco Santarelli, [7]Frank Jessen, [8]Michael T Heneka [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-018-0353-3
PubMed: 29482610
cerebrospinal fluid [curation]2018-02-26
Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).[1]Frank Jessen, [2]Annika Spottke, [3]Henning Boecker, [4]Frederic Brosseron, [5]Katharina Buerger, [6]Cihan Catak, [7]Klaus Fliessbach, [8]Christiana Franke, [9]Manuel Fuentes, [10]Michael T Heneka, ... [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-017-0314-2
PubMed: 29415768
Alzheimer's disease [curation]2018-02-07
Age-related functional changes in domain-specific medial temporal lobe pathways.[1]David Berron, [2]Katja Neumann, [3]Anne Maass, [4]Hartmut Schütze, [5]Klaus Fliessbach, [6]Verena Kiven, [7]Frank Jessen, [8]Magdalena Sauvage, [9]Dharshan Kumaran, [10]Emrah Düzel [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2017.12.030
PubMed: 29454154
2018-01-31
A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests[1]Matthias L Schroeter, [2]Sarah Pawelke, [3]Sandrine Bisenius, [4]Jana Kynast, [5]Katharina Schuemberg, [6]Maryna Polyakova, [7]Sarah Anderl-Straub, [8]Adrian Danek, [9]Klaus Fassbender, [10]Holger Jahn, [11]Frank Jessen, [12]Johannes Kornhuber, [13]Martin Lauer, [14]Johannes Prudlo, [15]Anja Schneider, [16]Ingo Uttner, [17]Angelika Thöne-Otto, [18]Markus Otto, [19]Janine Diehl-Schmid [Full author list]Frontiers in Aging Neuroscience [curation]DOI: 10.3389/FNAGI.2018.00011
PubMed: 29441012
frontotemporal dementia [curation]; Reading the Mind in the Eyes [curation]2018-01-30
Cognitive Complaints in Memory Clinic Patients and in Depressive Patients: An Interpretative Phenomenological Analysis.[1]Lisa Miebach, [2]Steffen Wolfsgruber, [3]Ingo Frommann, [4]Klaus Fließbach, [5]Frank Jessen, [6]Rachel Buckley, [7]Michael Wagner [Full author list]Gerontologist [curation]DOI: 10.1093/GERONT/GNX208
PubMed: 29325011
2018-01-08
Networks of tau distribution in Alzheimer's disease[1]Merle C Hoenig, [2]Gérard N Bischof, [3]Joseph Seemiller, [4]Jochen Hammes, [5]Juraj Kukolja, [6]Özgür A Onur, [7]Frank Jessen, [8]Klaus Fliessbach, [9]Bernd Neumaier, [10]Gereon Rudolf Fink, [11]Thilo van Eimeren, [12]Alexander Drzezga [Full author list]Brain [curation]DOI: 10.1093/BRAIN/AWX353
PubMed: 29315361
Alzheimer's disease [curation]2018-01-05
Perspective of elderly patients on chronic use of potentially inappropriate medication - Results of the qualitative CIM-TRIAD study[1]Kathrin Heser, [2]Nadine Janis Pohontsch, [3]Martin Scherer, [4]Antje Löffler, [5]Tobias Luck, [6]Steffi G. Riedel-Heller, [7]Wolfgang Maier, [8]Debora Parker, [9]Britta Haenisch, [10]Frank Jessen [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0202068
PubMed: 30231027
2018-01-01
Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease[1]Stefan J Teipel, [2]Coraline D Metzger, [3]Frederic Brosseron, [4]Katharina Buerger, [5]Katharina Brueggen, [6]Cihan Catak, [7]Dominik Diesing, [8]Laura Dobisch, [9]Klaus Fliebach, [10]Christiana Franke, ..., [23]Michael Wagner, [24]Emrah Düzel, [25]Frank Jessen, [26]Martin Dyrba, [27]DELCODE study group [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-180106
PubMed: 29914027
dementia [curation]2018-01-01
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry[1]Piotr Lewczuk, [2]Peter Riederer, [3]Sid E O'Bryant, [4]Marcel Verbeek, [5]Bruno Dubois, [6]Pieter Jelle Visser, [7]Kurt Jellinger, [8]Sebastiaan Engelborghs, [9]Alfredo Ramirez, [10]Lucilla Parnetti, ..., [13]Harald Hampel, [14]Alberto Lleó, [15]Frank Jessen, [16]Lidia Glodzik, [17]Mony J de Leon, ... [Full author list]World Journal of Biological Psychiatry [curation]DOI: 10.1080/15622975.2017.1375556
PubMed: 29076399
psychiatry [curation]; cerebrospinal fluid [curation]; biomarker [curation]; neurodegeneration [curation]2017-10-27
Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia[1]Lutz Frölich, [2]Olive Melissa Minor Peters, [3]Piotr Lewczuk, [4]Oliver Gruber, [5]Stefan J Teipel, [6]Hermann J Gertz, [7]Holger Jahn, [8]Frank Jessen, [9]Alexander Kurz, [10]Christian Luckhaus, ... [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-017-0301-7
PubMed: 29017593
Alzheimer's disease [curation]; biomarker [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2017-10-10
Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants[1]Jan Rehker, [2]Johanna Rodhe, [3]Ryan R Nesbitt, [4]Evan A Boyle, [5]Beth K Martin, [6]Jenny Lord, [7]Ilker Karaca, [8]Adam C Naj, [9]Frank Jessen, [10]Seppo Helisalmi, [11]Hilkka Soininen, ... [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0185777
PubMed: 28985224
Alzheimer's disease [curation]2017-10-06
In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults.[1]Matthew J Betts, [2]Arturo Cardenas-Blanco, [3]Martin Kanowski, [4]Frank Jessen, [5]Emrah Düzel [Full author list]NeuroImage [curation]DOI: 10.1016/J.NEUROIMAGE.2017.09.042
PubMed: 28943414
2017-09-21
Tau plasma levels in subjective cognitive decline: Results from the DELCODE study[1]Stephan Müller, [2]Oliver Preische, [3]Jens C Göpfert, [4]Viviana A Carcamo Yañez, [5]Thomas O Joos, [6]Henning Boecker, [7]Emrah Düzel, [8]Peter Falkai, [9]Josef Priller, [10]Katharina Buerger, ..., [24]Michael Wagner, [25]Jens Wiltfang, [26]Frank Jessen, [27]Christoph Laske [Full author list]Scientific Reports [curation]DOI: 10.1038/S41598-017-08779-0
PubMed: 28842559
2017-08-25
Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study[1]Janine Stein, [2]Alexander Pabst, [3]Tobias Luck, [4]Dagmar Lühmann, [5]Kathrin Heser, [6]Frank Jessen, [7]Horst Bickel, [8]Edelgard Mösch, [9]Michael Pentzek, [10]Angela Fuchs, [11]Birgitt Wiese, [12]Silke Mamone, [13]Hans-Helmut König, [14]Christian Brettschneider, [15]Jochen Werle, [16]Martin Scherer, [17]Wolfgang Maier, [18]Siegfried Weyerer, [19]Steffi G. Riedel-Heller, [20]AgeCoDe and AgeQualiDe Study Group [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000478850
PubMed: 28738341
2017-07-25
Subjective cognitive decline is longitudinally associated with lower health-related quality of life[1]Susanne Roehr, [2]Tobias Luck, [3]Alexander Pabst, [4]Horst Bickel, [5]Hans-Helmut König, [6]Dagmar Lühmann, [7]Angela Fuchs, [8]Steffen Wolfsgruber, [9]Birgitt Wiese, [10]Siegfried Weyerer, ..., [18]Martin Scherer, [19]Wolfgang Maier, [20]Frank Jessen, [21]Steffi G. Riedel-Heller, [22]AgeCoDe study group [Full author list]International Psychogeriatrics [curation]DOI: 10.1017/S1041610217001399
PubMed: 28737118
2017-07-24
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease[1]Rebecca Sims, [3]Adam C Naj, [6]Johanna Jakobsdottir, [7]Brian W Kunkle, [8]Anne Boland, [9]Rachel Raybould, [10]Joshua C Bis, ..., [127]Ryan M Huebinger, [128]Frank Jessen, [129]Shuo Li, [130]M. Ilyas Kamboh, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG.3916
PubMed: 28714976
Alzheimer's disease [curation]; microglia [curation]2017-07-17
Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment[1]Steffen Wolfsgruber, [2]Alexandra Polcher, [3]Alexander Koppara, [4]Luca Kleineidam, [5]Lutz Frölich, [6]Olive Melissa Minor Peters, [7]Michael Hull, [8]Eckart Rüther, [9]Jens Wiltfang, [10]Wolfgang Maier, [11]Johannes Kornhuber, [12]Piotr Lewczuk, [13]Frank Jessen, [14]Michael Wagner [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-161252
PubMed: 28527210
cerebrospinal fluid [curation]; biomarker [curation]; mild cognitive impairment [curation]2017-05-13
A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory[1]Virginie Freytag, [2]Tania Carrillo-Roa, [3]Annette Milnik, [4]Philipp G Sämann, [5]Vanja Vukojevic, [6]David Coynel, [7]Philippe Demougin, [8]Tobias Egli, [9]Leo Gschwind, [10]Frank Jessen, [11]Eva Loos, [12]Wolfgang Maier, [13]Steffi G. Riedel-Heller, [14]Martin Scherer, [15]Christian Vogler, [16]Michael Wagner, [17]Elisabeth Binder, [18]Dominique de Quervain, [19]Andreas Papassotiropoulos [Full author list]Nature Communications [curation]DOI: 10.1038/NCOMMS15193
PubMed: 28443631
2017-04-26
Reduced future-oriented decision making in individuals with subjective cognitive decline: A functional MRI study[1]Xiaochen Hu, [2]Franziska Uhle, [3]Klaus Fliessbach, [4]Michael Wagner, [5]Ying Han, [6]Bernd Weber, [7]Frank Jessen [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2017.02.005
PubMed: 28393099
decision making [curation]2017-03-14
Non-Pharmacologic Interventions for Older Adults with Subjective Cognitive Decline: Systematic Review, Meta-Analysis, and Preliminary Recommendations[1]Colette M Smart, [2]Justin E Karr, [3]Corson N Areshenkoff, [4]Laura A Rabin, [5]Carol Hudon, [6]Nicola Gates, [7]Jordan I Ali, [8]Eider M Arenaza-Urquijo, [9]Rachel F Buckley, [10]Gael Chetelat, [11]Harald Hampel, [12]Frank Jessen, [13]Natalie L Marchant, [14]Sietske A M Sikkes, [15]Andrea Tales, [16]Wiesje van der Flier, [17]Linda Wesselman, [18]and the Subjective Cognitive Decline Initiative (SCD-I) Working Group [Full author list]Neuropsychology Review [curation]DOI: 10.1007/S11065-017-9342-8
PubMed: 28271346
2017-03-07
General practitioners' views on (long-term) prescription and use of problematic and potentially inappropriate medication for oldest-old patients-A qualitative interview study with GPs (CIM-TRIAD study)[1]Nadine Janis Pohontsch, [2]Kathrin Heser, [3]Antje Löffler, [4]Britta Haenisch, [5]Debora Parker, [6]Tobias Luck, [7]Steffi G. Riedel-Heller, [8]Wolfgang Maier, [9]Frank Jessen, [10]Martin Scherer [Full author list]BMC Family Practice [curation]DOI: 10.1186/S12875-017-0595-3
PubMed: 28212616
2017-02-17
Predicting primary progressive aphasias with support vector machine approaches in structural MRI data[1]Sandrine Bisenius, [2]Karsten Mueller, [3]Janine Diehl-Schmid, [4]Klaus Fassbender, [5]Timo Grimmer, [6]Frank Jessen, [7]Jan Kassubek, [8]Johannes Kornhuber, [9]Bernhard Landwehrmeyer, [10]Albert C. Ludolph, [11]Anja Schneider, [12]Sarah Anderl-Straub, [13]Katharina Stuke, [14]Adrian Danek, [15]Markus Otto, [16]Matthias L. Schroeter, [17]FTLDc study group [Full author list]NeuroImage: Clinical [curation]DOI: 10.1016/J.NICL.2017.02.003
PubMed: 28229040
aphasia [curation]; support vector machine [curation]2017-02-06
Predicting behavioral variant frontotemporal dementia with pattern classification in multi-center structural MRI data[1]Sebastian Meyer, [2]Karsten Mueller, [3]Katharina Stuke, [4]Sandrine Bisenius, [5]Janine Diehl-Schmid, [6]Frank Jessen, [7]Jan Kassubek, [8]Johannes Kornhuber, [9]Albert C. Ludolph, [10]Johannes Prudlo, [11]Anja Schneider, [12]Katharina Schuemberg, [13]Igor Yakushev, [14]Markus Otto, [15]Matthias L. Schroeter, [16]FTLDc Study Group [Full author list]NeuroImage: Clinical [curation]DOI: 10.1016/J.NICL.2017.02.001
PubMed: 28348957
frontotemporal dementia [curation]; dementia [curation]2017-02-06
Face-Name Associative Recognition Deficits in Subjective Cognitive Decline and Mild Cognitive Impairment.[1]Alexandra Polcher, [2]Ingo Frommann, [3]Alexander Koppara, [4]Steffen Wolfsgruber, [5]Frank Jessen, [6]Michael Wagner [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-160637
PubMed: 28106560
2017-01-19
Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer[1]Guido Neidhardt, [2]Jan Hauke, [3]Juliane Ramser, [4]Eva Groß, [5]Andrea Gehrig, [6]Clemens R Müller, [7]Anne-Karin Kahlert, [8]Karl Hackmann, [9]Ellen Honisch, [10]Dieter Niederacher, ..., [18]Corinna Ernst, [19]Nina Ditsch, [20]Frank Jessen, [21]Alfredo Ramirez, [22]Barbara Wappenschmidt, ... [Full author list]JAMA Oncology [curation]DOI: 10.1001/JAMAONCOL.2016.5592
PubMed: 28033443
2016-12-29
TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis[1]Julie van der Zee, [2]Ilse Gijselinck, [3]Sara Van Mossevelde, [4]Federica Perrone, [5]Lubina Dillen, [6]Bavo Heeman, [7]Veerle Bäumer, [8]Sebastiaan Engelborghs, [9]Jan L De Bleecker, [10]Jonathan Baets, ..., [30]Frederico Simões do Couto, [31]Alfredo Ramirez, [32]Frank Jessen, [33]Michael T Heneka, [34]Estrella Gómez-Tortosa, ... [Full author list]Human Mutation [curation]DOI: 10.1002/HUMU.23161
PubMed: 28008748
frontotemporal dementia [curation]; dementia [curation]; patient [curation]; amyotrophic lateral sclerosis [curation]2016-12-23
Impact of coronary heart disease on cognitive decline in Alzheimer's disease: a prospective longitudinal cohort study in primary care[1]Markus Bleckwenn, [2]Luca Kleineidam, [3]Michael Wagner, [4]Frank Jessen, [5]Siegfried Weyerer, [6]Jochen Werle, [7]Birgitt Wiese, [8]Dagmar Lühmann, [9]Tina Posselt, [10]Hans-Helmut König, [11]Christian Brettschneider, [12]Edelgard Mösch, [13]Dagmar Weeg, [14]Angela Fuchs, [15]Michael Pentzek, [16]Tobias Luck, [17]Steffi G. Riedel-Heller, [18]Wolfgang Maier, [19]Martin Scherer [Full author list]British Journal of General Practice [curation]DOI: 10.3399/BJGP16X688813
PubMed: 27993897
Alzheimer's disease [curation]; coronary artery disease [curation]2016-12-19
Implementation of subjective cognitive decline criteria in research studies[1]José Luis Molinuevo, [2]Laura A Rabin, [3]Rebecca E. Amariglio, [4]Rachel F Buckley, [6]Kathryn A Ellis, [7]Michael Ewers, [8]Harald Hampel, [9]Stefan Klöppel, [10]Lorena Rami, [11]Barry Reisberg, [13]Sietske Sikkes, [14]Colette M Smart, [15]Beth E Snitz, [16]Reisa Sperling, [17]Wiesje van der Flier, [18]Michael Wagner, [19]Frank Jessen, [20]Subjective Cognitive Decline Initiative (SCD-I) Working Group [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2016.09.012
PubMed: 27825022
2016-11-05
Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease[1]Gérard N Bischof, [2]Frank Jessen, [3]Klaus Fliessbach, [4]Julian Dronse, [5]Jochen Hammes, [6]Bernd Neumaier, [7]Oezguer Onur, [8]Gereon Rudolf Fink, [9]Juraj Kukolja, [10]Alexander Drzezga, [11]Thilo van Eimeren, [12]Alzheimer's Disease Neuroimaging Initiative [Full author list]Annals of clinical and translational neurology [curation]DOI: 10.1002/ACN3.339
PubMed: 28097205
Alzheimer's disease [curation]; glucose [curation]2016-10-20
In vivo Patterns of Tau Pathology, Amyloid-β Burden, and Neuronal Dysfunction in Clinical Variants of Alzheimer's Disease.[1]Julian Dronse, [2]Klaus Fliessbach, [3]Gérard N Bischof, [4]Boris von Reutern, [5]Jennifer Faber, [6]Jochen Hammes, [7]Georg Kuhnert, [8]Bernd Neumaier, [9]Oezguer A Onur, [10]Juraj Kukolja, [11]Thilo van Eimeren, [12]Frank Jessen, [13]Gereon Rudolf Fink, [14]Thomas Klockgether, [15]Alexander Drzezga [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-160316
PubMed: 27802224
pathology [curation]; Alzheimer's disease [curation]2016-10-11
Differential Risk of Incident Alzheimer's Disease Dementia in Stable Versus Unstable Patterns of Subjective Cognitive Decline[1]Steffen Wolfsgruber, [2]Luca Kleineidam, [3]Michael Wagner, [4]Edelgard Mösch, [5]Horst Bickel, [6]Dagmar Lϋhmann, [7]Annette Ernst, [8]Birgitt Wiese, [9]Susanne Steinmann, [10]Hans-Helmut König, ..., [19]Martin Scherer, [20]Steffi G. Riedel-Heller, [21]Frank Jessen, [22]AgeCoDe Study Group [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-160407
PubMed: 27567852
Alzheimer's disease [curation]; dementia [curation]2016-08-24
No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment.[1]Katharina Bey, [2]Steffen Wolfsgruber, [3]Ilker Karaca, [4]Holger Wagner, [5]Roy Lardenoije, [6]Julian Becker, [7]Esther Milz, [8]Johannes Kornhuber, [9]Oliver Peters, [10]Lutz Frölich, ..., [14]Steffi G. Riedel-Heller, [15]Martin Scherer, [16]Frank Jessen, [17]Wolfgang Maier, [18]Daniel van den Hove, ... [Full author list]Epigenomics [curation]DOI: 10.2217/EPI-2015-0014
PubMed: 27092400
mild cognitive impairment [curation]2016-04-19
Defeating Alzheimer's disease and other dementias: a priority for European science and society[1]Bengt Winblad, [2]Philippe Amouyel, [3]Sandrine Andrieu, [4]Clive Ballard, [5]Carol Brayne, [6]Henry Brodaty, [7]Angel Cedazo-Minguez, [8]Bruno Dubois, [9]David Edvardsson, [10]Howard Feldman, ..., [15]Caroline Graff, [16]Khalid Iqbal, [17]Frank Jessen, [18]Gunilla Johansson, [19]Linus Jönsson, ... [Full author list]Lancet Neurology [curation]DOI: 10.1016/S1474-4422(16)00062-4
PubMed: 26987701
Alzheimer's disease [curation]2016-04-01
Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment[1]Eva Louwersheimer, [2]Steffen Wolfsgruber, [3]Ana Espinosa, [4]André Lacour, [5]Stefanie Heilmann-Heimbach, [6]Montserrat Alegret, [7]Isabel Hernández, [8]Maitée Rosende-Roca, [9]Lluís Tárraga, [10]Mercè Boada, ..., [17]Martin Scherer, [18]Steffi G. Riedel-Heller, [19]Frank Jessen, [20]Markus M Nöthen, [21]Wolfgang Maier, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2016.01.006
PubMed: 26921674
Alzheimer's disease [curation]; mild cognitive impairment [curation]; endophenotype [curation]2016-02-24
Incident Subjective Cognitive Decline Does Not Predict Mortality in the Elderly--Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe).[1]Susanne Roehr, [2]Tobias Luck, [3]Kathrin Heser, [4]Angela Fuchs, [5]Annette Ernst, [6]Birgitt Wiese, [7]Jochen Werle, [8]Horst Bickel, [9]Christian Brettschneider, [10]Alexander Koppara, ..., [17]Wolfgang Maier, [18]Martin Scherer, [19]Frank Jessen, [20]Steffi G. Riedel-Heller, [21]AgeCoDe Study Group [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0147050
PubMed: 26766555
dementia [curation]2016-01-14
A Reduction in Delay Discounting by Using Episodic Future Imagination and the Association with Episodic Memory Capacity[1]Xiaochen Hu, [2]Helena Kleinschmidt, [3]Jason A. Martin, [4]Ying Han, [5]Manuela Thelen, [6]Dix Meiberth, [7]Frank Jessen, [8]Bernd Weber [Full author list]Frontiers in Human Neuroscience [curation]DOI: 10.3389/FNHUM.2016.00663
PubMed: 28105009
episodic memory [curation]2016-01-01
Abnormal Resting-State Functional Connectivity Strength in Mild Cognitive Impairment and Its Conversion to Alzheimer's Disease[1]Yuxia Li, [2]Xiaoni Wang, [3]Yongqiu Li, [4]Yu Sun, [5]Can Sheng, [6]Hongyan Li, [7]Xuanyu Li, [8]Yang Yu, [9]Guanqun Chen, [10]Xiaochen Hu, [11]Bin Jing, [12]Defeng Wang, [13]Kuncheng Li, [14]Frank Jessen, [15]Mingrui Xia, [16]Ying Han [Full author list]Neural Plasticity [curation]DOI: 10.1155/2016/4680972
PubMed: 26843991
Alzheimer's disease [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2015-12-30
O2‐02‐04: The latent dementia phenotype δ is associated with the CSF Alzheimer's disease biomarker signature in subjects with mild cognitive impairment[1]Alexander Koppara, [2]Steffen Wolfsgruber, [3]Luca Kleineidam, [4]Klaus Schmidtke, [5]Lutz Frölich, [6]Alexander Kurz, [7]Stefanie Schulz, [8]Harald Hampel, [9]Isabella Heuser, [10]Oliver Peters, ..., [22]Wolfgang Maier, [23]Johannes Kornhuber, [24]Frank Jessen, [25]Michael Wagner [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2015.07.139
2015-12-15
Longitudinal Predictors of Institutionalization in Old Age.[1]André Hajek, [2]Christian Brettschneider, [3]Carolin Lange, [4]Tina Posselt, [5]Birgitt Wiese, [6]Susanne Steinmann, [7]Siegfried Weyerer, [8]Jochen Werle, [9]Michael Pentzek, [10]Angela Fuchs, ..., [14]Edelgard Mösch, [15]Michael Wagner, [16]Frank Jessen, [17]Wolfgang Maier, [18]Martin Scherer, ... [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0144203
PubMed: 26658776
2015-12-14
TREM2 rare variant p.R47H is not associated with Parkinson's disease.[1]David Mengel, [2]Mathias Thelen, [3]Monika Balzer-Geldsetzer, [4]Charlotte Söling, [5]Jan-Philipp Bach, [6]Eva Schaeffer, [7]Christine Herold, [8]Tim Becker, [9]Inga Liepelt, [10]Julian Becker, [11]Steffi G. Riedel-Heller, [12]Martin Scherer, [13]Frank Jessen, [14]Wolfgang Maier, [15]Richard Dodel, [16]Alfredo Ramirez [Full author list]Parkinsonism and Related Disorders [curation]DOI: 10.1016/J.PARKRELDIS.2015.11.026
PubMed: 26651418
2015-11-25
Longitudinal predictors of informal and formal caregiving time in community-dwelling dementia patients[1]André Hajek, [2]Christian Brettschneider, [3]Annette Ernst, [4]Tina Posselt, [5]Birgitt Wiese, [6]Jana Prokein, [7]Siegfried Weyerer, [8]Jochen Werle, [9]Angela Fuchs, [10]Michael Pentzek, [11]Janine Stein, [12]Steffi G. Riedel-Heller, [13]Horst Bickel, [14]Edelgard Mösch, [15]Kathrin Heser, [16]Frank Jessen, [17]Wolfgang Maier, [18]Martin Scherer, [19]Hans-Helmut König [Full author list]Social Psychiatry and Psychiatric Epidemiology [curation]DOI: 10.1007/S00127-015-1138-7
PubMed: 26498751
dementia [curation]2015-10-23
Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease.[1]Oliver Peters, [2]Manuel Fuentes, [3]Lisa Katharina Joachim, [4]Frank Jessen, [5]Christian Luckhaus, [6]Johannes Kornhuber, [7]Johannes Pantel, [8]Michael Hüll, [9]Klaus Schmidtke, [10]Eckart Rüther, [11]Hans-Jürgen Möller, [12]Alexander Kurz, [13]Jens Wiltfang, [14]Wolfgang Maier, [15]Birgitt Wiese, [16]Lutz Frölich, [17]Isabella Heuser [Full author list]Alzheimer's & dementia (New York, N. Y.) [curation]DOI: 10.1016/J.TRCI.2015.10.001
PubMed: 29854939
2015-10-19
The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment[1]Alexander Koppara, [2]Steffen Wolfsgruber, [3]Luca Kleineidam, [4]Klaus Schmidtke, [5]Lutz Frölich, [6]Alexander Kurz, [7]Stefanie Schulz, [8]Harald Hampel, [9]Isabella Heuser, [10]Oliver Peters, ..., [21]Jens Wiltfang, [22]Wolfgang Maier, [23]Frank Jessen, [24]Johannes Kornhuber, [25]Michael Wagner [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150257
PubMed: 26484902
Alzheimer's disease [curation]; cerebrospinal fluid [curation]; dementia [curation]; biomarker [curation]; mild cognitive impairment [curation]2015-10-17
Feature Binding Deficits in Subjective Cognitive Decline and in Mild Cognitive Impairment[1]Alexander Koppara, [2]Ingo Frommann, [3]Alexandra Polcher, [4]Mario A Parra, [5]Wolfgang Maier, [6]Frank Jessen, [7]Thomas Klockgether, [8]Michael Wagner [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150105
PubMed: 26402080
mild cognitive impairment [curation]2015-09-18
Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease[1]Angela Heck, [2]Matthias Fastenrath, [3]David Coynel, [4]Bianca Auschra, [5]Horst Bickel, [6]Virginie Freytag, [7]Leo Gschwind, [8]Francina Hartmann, [9]Frank Jessen, [10]Hanna Kaduszkiewicz, [11]Wolfgang Maier, ... [Full author list]JAMA Psychiatry [curation]DOI: 10.1001/JAMAPSYCHIATRY.2015.1309
PubMed: 26332608
Alzheimer's disease [curation]2015-09-02
Subjective Cognitive Decline[1]Andrea Tales, [2]Frank Jessen, [3]Christopher C. Butler, [4]Gordon Wilcock, [5]Judith Phillips, [6]Antony Bayer [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150719
PubMed: 26445272
2015-09-01
Amyloid Pathology, Cognitive Impairment, and Alzheimer Disease Risk.[1]Michael Wagner, [2]Frank Jessen [Full author list]The Journal of the American Medical Association [curation]DOI: 10.1001/JAMA.2015.9716
PubMed: 26372590
cognitive dysfunction [curation]2015-09-01
Computational dissection of human episodic memory reveals mental process-specific genetic profiles[1]Gediminas Luksys, [2]Matthias Fastenrath, [3]David Coynel, [4]Virginie Freytag, [5]Leo Gschwind, [6]Angela Heck, [7]Frank Jessen, [8]Wolfgang Maier, [9]Annette Milnik, [10]Steffi G. Riedel-Heller, [11]Martin Scherer, [12]Klara Spalek, [13]Christian Vogler, [14]Michael Wagner, [15]Steffen Wolfsgruber, [16]Andreas Papassotiropoulos, [17]Dominique J-F de Quervain [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.1500860112
PubMed: 26261317
episodic memory [curation]2015-08-10
Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline[1]Simone Lista, [2]Jose L Molinuevo, [3]Enrica Cavedo, [4]Lorena Rami, [5]Philippe Amouyel, [6]Stefan J Teipel, [7]Francesco Garaci, [8]Nicola Toschi, [9]Marie-Odile Habert, [10]Kaj Blennow, ..., [18]Hovagim Bakardjian, [19]Bruno Dubois, [20]Frank Jessen, [21]Maria C Carrillo, [22]Paul S. Aisen, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150202
PubMed: 26402088
neuroimaging [curation]2015-08-06
Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies[1]Laura Rabin, [2]Colette M Smart, [3]Paul K. Crane, [4]Rebecca E. Amariglio, [5]Lorin M Berman, [6]Mercé Boada, [7]Rachel F Buckley, [8]Gaël Chételat, [9]Bruno Dubois, [10]Kathryn A Ellis, [11]Katherine A. Gifford, [12]Angela L. Jefferson, [13]Frank Jessen, [14]Mindy J. Katz, [15]Richard B. Lipton, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150154
PubMed: 26402085
2015-08-01
Mortality in Individuals with Subjective Cognitive Decline: Results of the Leipzig Longitudinal Study of the Aged (LEILA75+).[1]Tobias Luck, [2]Susanne Roehr, [3]Frank Jessen, [4]Arno Villringer, [5]Matthias C Angermeyer, [6]Steffi G. Riedel-Heller [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150090
PubMed: 26402077
2015-07-28
Influence of Sampling and Recruitment Methods in Studies of Subjective Cognitive Decline[1]Octavio Rodríguez-Gómez, [2]Carla Abdelnour, [3]Frank Jessen, [4]Sergi Valero, [5]Merçé Boada [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-150189
PubMed: 26402087
2015-07-01
Complex coevolution of depression and health-related quality of life in old age.[1]André Hajek, [2]Christian Brettschneider, [3]Annette Ernst, [4]Carolin Lange, [5]Birgitt Wiese, [6]Jana Prokein, [7]Siegfried Weyerer, [8]Jochen Werle, [9]Michael Pentzek, [10]Angela Fuchs, [11]Janine Stein, [12]Horst Bickel, [13]Edelgard Mösch, [14]Kathrin Heser, [15]Frank Jessen, [16]Wolfgang Maier, [17]Martin Scherer, [18]Steffi G. Riedel-Heller, [19]Hans-Helmut König [Full author list]Quality of Life Research [curation]DOI: 10.1007/S11136-015-1005-8
PubMed: 25986907
2015-05-19
Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study[1]Katrin Morgen, [2]Michael Schneider, [3]Lutz Frölich, [4]Heike Tost, [5]Michael M Plichta, [6]Heike Kölsch, [7]Fabian Rakebrandt, [8]Otto Rienhoff, [9]Frank Jessen, [10]Olive Melissa Minor Peters, [11]Holger Jahn, ... [Full author list]Alzheimers Research & Therapy [curation]DOI: 10.1186/S13195-015-0111-8
PubMed: 25984242
Alzheimer's disease [curation]2015-05-15
Cognitive performance before and after the onset of subjective cognitive decline in old age.[1]Alexander Koppara, [2]Michael Wagner, [3]Carolin Lange, [4]Annette Ernst, [5]Birgitt Wiese, [6]Hans-Helmut König, [7]Christian Brettschneider, [8]Steffi G. Riedel-Heller, [9]Melanie Luppa, [10]Siegfried Weyerer, [11]Jochen Werle, [12]Horst Bickel, [13]Edelgard Mösch, [14]Michael Pentzek, [15]Angela Fuchs, [16]Steffen Wolfsgruber, [17]André Beauducel, [18]Martin Scherer, [19]Wolfgang Maier, [20]Frank Jessen [Full author list]Alzheimer's & dementia (Amsterdam, Netherlands) [curation]DOI: 10.1016/J.DADM.2015.02.005
PubMed: 27239504
2015-05-02
PLD3 in non-familial Alzheimer's disease.[1]Stefanie Heilmann-Heimbach, [2]Dmitriy Drichel, [3]Jordi Clarimon, [4]Victoria Fernández, [5]André Lacour, [6]Holger Wagner, [7]Mathias Thelen, [8]Isabel Hernández, [9]Juan Fortea, [10]Montserrat Alegret, ..., [22]Martin Scherer, [23]Jens Wiltfang, [24]Frank Jessen, [25]Tim Becker, [26]Lluís Tárraga, ... [Full author list]Nature [curation]DOI: 10.1038/NATURE14039
PubMed: 25832411
Alzheimer's disease [curation]2015-04-01
CSF biomarkers for the differential diagnosis of Alzheimer's disease: A large-scale international multicenter study.[1]Michael Ewers, [2]Niklas Mattsson, [3]Lennart Minthon, [4]José Luis Molinuevo, [5]Anna Antonell, [6]Julius Popp, [7]Frank Jessen, [8]Sanna-Kaisa Herukka, [9]Hilka Soininen, [10]Walter Maetzler, [11]Thomas Leyhe, [12]Katharina Bürger, [13]Miyako Taniguchi, [14]Katsuya Urakami, [15]Simone Lista, [16]Bruno Dubois, [17]Kaj Blennow, [18]Harald Hampel [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2014.12.006
PubMed: 25804998
Alzheimer's disease [curation]; biomarker [curation]2015-03-21
Novel genetic matching methods for handling population stratification in genome-wide association studies[1]André Lacour, [2]Vitalia Schüller, [3]Dmitriy Drichel, [4]Christine Herold, [5]Frank Jessen, [6]Markus Leber, [7]Wolfgang Maier, [8]Markus M Noethen, [9]Alfredo Ramirez, [10]Tatsiana Vaitsiakhovich, [11]Tim Becker [Full author list]BMC Bioinformatics [curation]DOI: 10.1186/S12859-015-0521-4
PubMed: 25880419
genome-wide association study [curation]2015-03-14
Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.[1]Steffen Wolfsgruber, [2]Frank Jessen, [3]Alexander Koppara, [4]Luca Kleineidam, [5]Klaus Schmidtke, [6]Lutz Frölich, [7]Alexander Kurz, [8]Stefanie Schulz, [9]Harald Hampel, [10]Isabella Heuser, ..., [19-Q48786171]Otto Rienhoff, ... [Full author list]Neurology [curation]DOI: 10.1212/WNL.0000000000001399
PubMed: 25716354
biomarker [curation]2015-02-25
Anatomical correlates of the neuropsychiatric symptoms in Alzheimer's disease[1]Xiaochen Hu, [2]Dix Meiberth, [3]Beate Newport, [4]Frank Jessen [Full author list]Current Alzheimer Research [curation]DOI: 10.2174/1567205012666150302154914
PubMed: 25731626
Alzheimer's disease [curation]2015-01-01
Elevated HbA1c is associated with increased risk of incident dementia in primary care patients[1]Alfredo Ramirez, [2]Steffen Wolfsgruber, [3]Carolin Lange, [4]Hanna Kaduszkiewicz, [5]Siegfried Weyerer, [6]Jochen Werle, [7]Michael Pentzek, [8]Angela Fuchs, [9]Steffi G. Riedel-Heller, [10]Tobias Luck, ..., [17]Monique Breteler, [18]Wolfgang Maier, [19]Frank Jessen, [20]Martin Scherer, [21]AgeCoDe Study Group [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-141521
PubMed: 25524954
2015-01-01
Cortical thinning in individuals with subjective memory impairment.[1]Dix Meiberth, [2]Lukas Scheef, [3]Steffen Wolfsgruber, [4]Henning Boecker, [5]Wolfgang Block, [6]Frank Traeber, [7]Susanne Erk, [8]Michael T Heneka, [9]Heike Jacobi, [10]Annika Spottke, [11]Henrik Walter, [12]Michael Wagner, [13]Xiaochen Hu, [14]Frank Jessen [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-142322
PubMed: 25471190
2015-01-01
Influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.[1]Eva Louwersheimer, [2]Alfredo Ramirez, [3]Carlos Cruchaga, [4]Tim Becker, [5]Johannes Kornhuber, [6]Olive Melissa Minor Peters, [7]Stefanie Heilmann-Heimbach, [8]Jens Wiltfang, [9]Frank Jessen, [10]Pieter Jelle Visser, [11]Philip Scheltens, [12]Yolande A L Pijnenburg, [13]Charlotte Teunissen, [14]Frederik Barkhof, [15]John Van Swieten, [16]Henne Holstege, [17]Wiesje van der Flier, [18]Alzheimer's Disease Neuroimaging Initiative and Dementia Competence Network [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2014.12.007
PubMed: 25659857
2014-12-11
Rare variant testing of imputed data: an analysis pipeline typified[1]Dmitriy Drichel, [2]Christine Herold, [3]André Lacour, [4]Alfredo Ramirez, [5]Frank Jessen, [6]Wolfgang Maier, [7]Markus M Nöthen, [8]Markus Leber, [9]Tatsiana Vaitsiakhovich, [10]Tim Becker [Full author list]Human Heredity [curation]DOI: 10.1159/000368676
PubMed: 25504234
2014-12-10
Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.[1]Julius Popp, [2]Steffen Wolfsgruber, [3]Isabella Heuser, [4]Oliver Peters, [5]Michael Hüll, [6]Johannes Schröder, [7]Hans-Jürgen Möller, [8]Piotr Lewczuk, [9]Anja Schneider, [10]Holger Jahn, [11]Christian Luckhaus, [12]Robert Perneczky, [13]Lutz Frölich, [14]Michael Wagner, [15]Wolfgang Maier, [16]Jens Wiltfang, [17]Johannes Kornhuber, [18]Frank Jessen [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2014.10.031
PubMed: 25435336
Alzheimer's disease [curation]; cerebrospinal fluid [curation]; dementia [curation]; cortisol [curation]2014-10-31
Risk of dementia in elderly patients with the use of proton pump inhibitors.[1]Britta Haenisch, [2]Klaus von Holt, [3]Birgitt Wiese, [4]Jana Prokein, [5]Carolin Lange, [6]Annette Ernst, [7]Christian Brettschneider, [8]Hans-Helmut König, [9]Jochen Werle, [10]Siegfried Weyerer, [11]Melanie Luppa, [12]Steffi G. Riedel-Heller, [13]Angela Fuchs, [14]Michael Pentzek, [15]Dagmar Weeg, [16]Horst Bickel, [17]Karl Broich, [18]Frank Jessen, [19]Wolfgang Maier, [20]Martin Scherer [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-014-0554-0
PubMed: 25341874
dementia [curation]; patient [curation]2014-10-24
The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk[1]Basavaraj V Hooli, [2]Antonio R Parrado, [3]Kristina Mullin, [4]Wai-Ki Yip, [5]Tian Liu, [6]Johannes T Roehr, [7]Dandi Qiao, [8]Frank Jessen, [9]Oliver Peters, [10]Tim Becker, [11]Alfredo Ramirez, [12]Christoph Lange, [13]Lars Bertram, [14]Rudolph E. Tanzi [Full author list]Neurology [curation]DOI: 10.1212/WNL.0000000000000855
PubMed: 25186855
Alzheimer's disease [curation]2014-09-03
The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.[1]Martina Bocchetta, [2]Samantha Galluzzi, [3]Patrick G. Kehoe, [4]Eduardo Aguera, [5]Roberto Bernabei, [6]Roger Bullock, [7]Mathieu Ceccaldi, [8]Jean-François Dartigues, [9]Alexandre de Mendonça, [10]Mira Didic, ..., [17]Lucrezia Hausner, [18]Isabell Heuser, [19]Frank Jessen, [20]Roy W Jones, [21]Alexander Kurz, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2014.06.006
PubMed: 25150733
biomarker [curation]2014-08-20
SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease[1]Alfredo Ramirez, [2]Wiesje van der Flier, [3]Christine Herold, [4]David Ramonet, [5]Stefanie Heilmann-Heimbach, [6]Piotr Lewczuk, [7]Julius Popp, [8]André Lacour, [9]Dmitriy Drichel, [10]Eva Louwersheimer, ..., [33]Jens Wiltfang, [34]Alison Goate, [35]Frank Jessen, [36]Wolfgang Maier, [37]Michael T Heneka, ... [Full author list]Human Molecular Genetics [curation]DOI: 10.1093/HMG/DDU372
PubMed: 25027320
Alzheimer's disease [curation]2014-07-15
Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment[1]Steffen Wolfsgruber, ..., [2]Michael Wagner, [3]Klaus Schmidtke, [4]Lutz Frölich, [5]Alexander Kurz, [6]Stefanie Schulz, [7]Harald Hampel, [8]Isabella Heuser, [9]Oliver Peters, [10]Friedel M. Reischies, ..., [21]Wolfgang Maier, [22]Johannes Kornhuber, [23]Frank Jessen [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0100812
PubMed: 25019225
dementia [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2014-07-14
N-acetyl-aspartate (NAA) as a correlate of pharmacological treatment in psychiatric disorders: a systematic review[1]Georgios Paslakis, [2]Frank Traeber, [3]Jens Roberz, [4]Wolfgang Block, [5]Frank Jessen [Full author list]European Neuropsychopharmacology [curation]DOI: 10.1016/J.EURONEURO.2014.06.004
PubMed: 25130303
systematic review [curation]2014-07-04
Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes[1]Mathias Thelen, [2]Cristina Razquin, [3]Isabel Hernández, [4]Ana Gorostidi, [5]Raquel Sanchez-Valle, [6]Sara Ortega-Cubero, [7]Steffen Wolfsgruber, [8]Dmitriy Drichel, [9]Klaus Fliessbach, [10]Tanja Duenkel, ..., [41]Mercè Boada, [42]Michael Wagner, [43]Frank Jessen, [44]Wolfgang Maier, [45]Jordi Clarimón, ... [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2014.06.018
PubMed: 25042114
frontotemporal dementia [curation]2014-06-20
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration[1]Julie van der Zee, [2]Tim Van Langenhove, [3]Gabor G. Kovacs, [4]Lubina Dillen, [5]William Deschamps, [6]Sebastiaan Engelborghs, [7]Radoslav Matěj, [8]Mathieu Vandenbulcke, [9]Anne Sieben, [10]Bart Dermaut, ..., [56]Beatriz Santiago González, [57]Michael T Heneka, [58]Frank Jessen, [59]Alfredo Ramirez, [60]Raquel Sanchez-Valle, ... [Full author list]Acta Neuropathologica [curation]DOI: 10.1007/S00401-014-1298-7
PubMed: 24899140
frontotemporal lobar degeneration [curation]2014-06-05
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease[1]Frank Jessen, [2]Rebecca E. Amariglio, [3]Martin van Boxtel, [4]Monique Breteler, [5]Mathieu Ceccaldi, [6]Gaël Chételat, [7]Bruno Dubois, [8]Carole Dufouil, [9]Kathryn A Ellis, [10]Wiesje van der Flier, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2014.01.001
PubMed: 24798886
Alzheimer's disease [curation]2014-05-03
Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.[1]Katrin Morgen, [2]Alfredo Ramirez, [3]Lutz Frölich, [4]Heike Tost, [5]Michael M Plichta, [6]Heike Kölsch, [7]Fabian Rakebrandt, [8]Otto Rienhoff, [9]Frank Jessen, [10]Olive Melissa Minor Peters, [11]Holger Jahn, ... [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2013.11.001
PubMed: 24613704
cognitive dysfunction [curation]2014-03-06
Prognosis of mild cognitive impairment in general practice: results of the German AgeCoDe study[1]Hanna Kaduszkiewicz, [2]Marion Eisele, [3]Birgitt Wiese, [4]Jana Prokein, [5]Melanie Luppa, [6]Tobias Luck, [7]Frank Jessen, [8]Horst Bickel, [9]Edelgard Mösch, [10]Michael Pentzek, [11]Angela Fuchs, [12]Sandra Eifflaender-Gorfer, [13]Siegfried Weyerer, [14]Hans-Helmut König, [15]Christian Brettschneider, [16]Hendrik van den Bussche, [17]Wolfgang Maier, [18]Martin Scherer, [19]Steffi G. Riedel-Heller, [20]Study on Aging, Cognition, and Dementia in Primary Care Patients (AgeCoDe) Study Group [Full author list]Annals of Family Medicine [curation]DOI: 10.1370/AFM.1596
PubMed: 24615312
mild cognitive impairment [curation]; cognitive dysfunction [curation]2014-03-01
DNA methylation of the TNF-α promoter region in peripheral blood monocytes and the cortex of human Alzheimer's disease patients.[1]Oliver Kaut, [2]Alfredo Ramirez, [3]Heike Pieper, [4]Ina Schmitt, [5]Frank Jessen, [6]Ullrich Wüllner [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000357126
PubMed: 24556805
Alzheimer's disease [curation]; DNA methylation [curation]; TNF [curation]2014-02-19
Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity[1]Angela Heck, [2]Matthias Fastenrath, [3]Sandra Ackermann, [4]Bianca Auschra, [5]Horst Bickel, [6]David Coynel, [7]Leo Gschwind, [8]Frank Jessen, [9]Hanna Kaduszkiewicz, [10]Wolfgang Maier, ... [Full author list]Neuron [curation]DOI: 10.1016/J.NEURON.2014.01.010
PubMed: 24529980
2014-02-13
The costs of dementia from the societal perspective: is care provided in the community really cheaper than nursing home care?[1]Hans-Helmut König, [2]Hanna Leicht, [3]Christian Brettschneider, [4]Cadja Bachmann, [5]Horst Bickel, [6]Angela Fuchs, [7]Frank Jessen, [8]Mirjam Köhler, [9]Melanie Luppa, [10]Edelgard Mösch, [11]Michael Pentzek, [12]Jochen Werle, [13]Siegfried Weyerer, [14]Birgitt Wiese, [15]Martin Scherer, [16]Wolfgang Maier, [17]Steffi G. Riedel-Heller, [18]AgeCoDe Study Group [Full author list]Journal of the American Medical Directors Association [curation]DOI: 10.1016/J.JAMDA.2013.10.003
PubMed: 24321877
dementia [curation]2013-12-08
A one-degree-of-freedom test for supra-multiplicativity of SNP effects[1]Christine Herold, [2]Alfredo Ramirez, [3]Dmitriy Drichel, [4]André Lacour, [5]Tatsiana Vaitsiakhovich, [6]Markus M Nöthen, [7]Frank Jessen, [8]Wolfgang Maier, [9]Tim Becker [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0078038
PubMed: 24205078
2013-10-30
Human genome-guided identification of memory-modulating drugs[1]Andreas Papassotiropoulos, [2]Christiane Gerhards, [3]Angela Heck, [4]Sandra Ackermann, [5]Amanda Aerni, [6]Nathalie Schicktanz, [7]Bianca Auschra, [8]Philippe Demougin, [9]Eva Mumme, [10]Thomas Elbert, ..., [13]Edveena Hanser, [14]Kim-Dung Huynh, [15]Frank Jessen, [16]Iris-Tatjana Kolassa, [17]Annette Milnik, ... [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.1314478110
PubMed: 24145423
2013-10-21
Structural and Functional Magnetic Resonance Imaging: Mild Cognitive Impairment and Alzheimer Disease[1]Hannah Lockau, [2]Frank Jessen, [3]Andreas Fellgiebel, [4]Alexander Drzezga [Full author list]PET clinics [curation]DOI: 10.1016/J.CPET.2013.08.004
PubMed: 27156470
Alzheimer's disease [curation]; functional magnetic resonance imaging [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2013-08-30
Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism[1]Maria A de Souza Silva, [2]Bernd Lenz, [3]Andrea Rotter, [4]Teresa Biermann, [5]Oliver Peters, [6]Alfredo Ramirez, [7]Frank Jessen, [8]Wolfgang Maier, [9]Michael Hüll, [10]Johannes Schröder, [11]Lutz Frölich, [12]Stefan J Teipel, [13]Oliver Gruber, [14]Johannes Kornhuber, [15]Joseph P Huston, [16]Christian P. Müller, [17]Sandra Schäble [Full author list]Proceedings of the National Academy of Sciences of the United States of America [curation]DOI: 10.1073/PNAS.1306884110
PubMed: 23983264
2013-08-27
Predictors of costs in dementia in a longitudinal perspective[1]Hanna Leicht, [2]Hans-Helmut König, [3]Nina Stuhldreher, [4]Cadja Bachmann, [5]Horst Bickel, [6]Angela Fuchs, [7]Kathrin Heser, [8]Frank Jessen, [9]Mirjam Köhler, [10]Melanie Luppa, [11]Edelgard Mösch, [12]Michael Pentzek, [13]Steffi G. Riedel-Heller, [14]Martin Scherer, [15]Jochen Werle, [16]Siegfried Weyerer, [17]Birgitt Wiese, [18]Wolfgang Maier, [19]AgeCoDe study group [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0070018
PubMed: 23875017
dementia [curation]2013-07-18
Gray matter atrophy pattern in elderly with subjective memory impairment[1]Jessica Peter, [2]Lukas Scheef, [3]Ahmed Abdulkadir, [4]Henning Boecker, [5]Michael Heneka, [6]Michael Wagner, [7]Alexander Koppara, [8]Stefan Klöppel, [9]Frank Jessen, [10]Alzheimer's Disease Neuroimaging Initiative [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2013.05.1764
PubMed: 23867795
2013-07-15
The CERAD neuropsychological assessment battery total score detects and predicts Alzheimer disease dementia with high diagnostic accuracy[1]Steffen Wolfsgruber, [2]Frank Jessen, [3]Birgitt Wiese, [4]Janine Stein, [5]Horst Bickel, [6]Edelgard Mösch, [7]Siegfried Weyerer, [8]Jochen Werle, [9]Michael Pentzek, [10]Angela Fuchs, [11]Mirjam Köhler, [12]Cadja Bachmann, [13]Steffi G. Riedel-Heller, [14]Martin Scherer, [15]Wolfgang Maier, [16]Michael Wagner, [17]AgeCoDe Study Group [Full author list]American Journal of Geriatric Psychiatry [curation]DOI: 10.1016/J.JAGP.2012.08.021
PubMed: 23759289
neuropsychology [curation]; Alzheimer's disease [curation]2013-06-04
Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease[1]Denise Harold, [2]Richard Abraham, [3]Paul Hollingworth, [4]Rebecca Sims, [5]Amy Gerrish, [6]Marian L Hamshere, [7]Jaspreet Singh Pahwa, [8]Valentina Escott-Price, [9]Kimberley Dowzell, [10]Amy Williams, ..., [39]John Collinge, [40]Wolfgang Maier, [41]Frank Jessen, [42]Britta Schürmann, [43]Reinhard Heun, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG0613-712A
genome-wide association study [curation]; Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease [curation]2013-06-01
Verbal memory deficits are correlated with prefrontal hypometabolism in (18)FDG PET of recreational MDMA users[1]Oliver G Bosch, [2]Michael Wagner, [3]Frank Jessen, [4]Kai-Uwe Kühn, [5]Alexius Joe, [6]Erich Seifritz, [7]Wolfgang Maier, [8]Hans-Jürgen Biersack, [9]Boris B Quednow [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0061234
PubMed: 23585882
2013-04-09
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial[1]Richard Dodel, [2]Axel Rominger, [3]Peter Bartenstein, [4]Frederik Barkhof, [5]Kaj Blennow, [6]Stefan Förster, [7]Yaroslav Winter, [8]Jan-Philipp Bach, [9]Julius Popp, [10]Judith Alferink, ..., [21]Stefan Wietek, [22]Martin R. Farlow, [23]Frank Jessen [Full author list]Lancet Neurology [curation]DOI: 10.1016/S1474-4422(13)70014-0
PubMed: 23375965
Alzheimer's disease [curation]; placebo [curation]; phase II clinical trial [curation]2013-01-31
AD dementia risk in late MCI, in early MCI, and in subjective memory impairment.[1]Frank Jessen, [2]Steffen Wolfsgruber, [3]Birgitt Wiese, [4]Horst Bickel, [5]Edelgard Mösch, [6]Hanna Kaduszkiewicz, [7]Michael Pentzek, [8]Steffi G. Riedel-Heller, [9]Tobias Luck, [10]Angela Fuchs, [11]Siegfried Weyerer, [12]Jochen Werle, [13]Hendrik van den Bussche, [14]Martin Scherer, [15]Wolfgang Maier, [16]Michael Wagner, [17]German Study on Aging, Cognition and Dementia in Primary Care Patients [Full author list]Alzheimer's and Dementia [curation]DOI: 10.1016/J.JALZ.2012.09.017
PubMed: 23375567
dementia [curation]2013-01-30
A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats[1]Julie van der Zee, [2]Ilse Gijselinck, [3]Lubina Dillen, [4]Tim Van Langenhove, [5]Jessie Theuns, [6]Sebastiaan Engelborghs, [7]Stéphanie Philtjens, [8]Mathieu Vandenbulcke, [9]Kristel Sleegers, [10]Anne Sieben, ..., [41]Ludger Schöls, [42]Michael T Heneka, [43]Frank Jessen, [44]Radoslav Matěj, [45]Eva Parobkova, ..., [105]Ludger Schöls, [106]Michael T Heneka, [107]Frank Jessen, [108]Alfredo Ramirez, [109]Delia Kurzwelly, ..., [152]Thomas Ströbel, [153]Michael T Heneka, [154]Frank Jessen, [155]Alfredo Ramirez, [156]Delia Kurzwelly, [157]Carmen Sachtleben, [158]Wolfgang Mairer, [159]Frank Jessen, [160]Radoslav Matěj, [161]Eva Parobkova, ... [Full author list]Human Mutation [curation]DOI: 10.1002/HUMU.22244
PubMed: 23111906
2013-01-04
Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease.[1]Julius Popp, [2]Sabrina Meichsner, [3]Heike Kölsch, [4]Piotr Lewczuk, [5]Wolfgang Maier, [6]Johannes Kornhuber, [7]Frank Jessen, [8]Dieter Lütjohann [Full author list]Biochemical Pharmacology [curation]DOI: 10.1016/J.BCP.2012.12.007
PubMed: 23291240
Alzheimer's disease [curation]2013-01-03
APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease.[1]Katrin Morgen, [2]Lutz Frölich, [3]Heike Tost, [4]Michael M Plichta, [5]Heike Kölsch, [6]Fabian Rakebrandt, [7]Otto Rienhoff, [8]Frank Jessen, [9]Olive Melissa Minor Peters, [10]Holger Jahn, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-130326
PubMed: 23948881
Alzheimer's disease [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2013-01-01
The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study.[1]José Luis Molinuevo, [2]Joan Domingo Gispert, [3]Bruno Dubois, [4]Michael T Heneka, [5]Alberto Lleo, [6]Sebastiaan Engelborghs, [7]Jesús Pujol, [8]Leonardo C de Souza, [9]Daniel A. Alcolea, [10]Frank Jessen, [11]Marie Sarazin, [12]Foudil Lamari, [13]Mircea Balasa, [14]Anna Antonell, [15]Lorena Rami [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-130203
PubMed: 23524657
Alzheimer's disease [curation]2013-01-01
Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.[1]Markus P Kummer, [2]Thomas Vogl, [3]Daisy Axt, [4]Angelika Griep, [5]Ana Vieira-Saecker, [6]Frank Jessen, [7]Ellen Gelpi, [8]Johannes Roth, [9]Michael T Heneka [Full author list]Journal of Neuroscience [curation]DOI: 10.1523/JNEUROSCI.1504-12.2012
PubMed: 23223301
phagocytosis [curation]; microglia [curation]2012-12-01
Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors[1]Alexander Semmler, [2]Catherine Nichols Widmann, [3]Thorsten Okulla, [4]Horst Urbach, [5]Markus Kaiser, [6]Guido Widman, [7]Florian Mormann, [8]Julia Weide, [9]Klaus Fliessbach, [10]Andreas Hoeft, [11]Frank Jessen, [12]Christian Putensen, [13]Michael T Heneka [Full author list]Journal of Neurology, Neurosurgery and Psychiatry [curation]DOI: 10.1136/JNNP-2012-302883
PubMed: 23134661
sepsis [curation]; cognitive dysfunction [curation]2012-11-07
Prediction of incident dementia: impact of impairment in instrumental activities of daily living and mild cognitive impairment-results from the German study on ageing, cognition, and dementia in primary care patients[1]Tobias Luck, [2]Melanie Luppa, [3]Birgit Wiese, [4]Wolfgang Maier, [5]Hendrik van den Bussche, [6]Marion Eisele, [7]Frank Jessen, [8]Dagmar Weeg, [9]Siegfried Weyerer, [10]Michael Pentzek, [11]Hanna Leicht, [12]Mirjam Koehler, [13]Franziska Tebarth, [14]Julia Olbrich, [15]Sandra Eifflaender-Gorfer, [16]Angela Fuchs, [17]Hans-Helmut Koenig, [18]Steffi G. Riedel-Heller, [19]AgeCoDe Study Group [Full author list]American Journal of Geriatric Psychiatry [curation]DOI: 10.1097/JGP.0B013E31825C09BC
PubMed: 22706332
dementia [curation]; patient [curation]; mild cognitive impairment [curation]2012-11-01
Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease.[1]Julius Popp, [2]Piotr Lewczuk, [3]Heike Kölsch, [4]Sabrina Meichsner, [5]Wolfgang Maier, [6]Johannes Kornhuber, [7]Frank Jessen, [8]Dieter Lütjohann [Full author list]Journal of Neurochemistry [curation]DOI: 10.1111/J.1471-4159.2012.07893.X
PubMed: 22845771
2012-08-23
Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment[1]Lukas Scheef, [2]Annika Spottke, [3]Moritz Daerr, [4]Alexius Joe, [5]Nadine Striepens, [6]Heike Kölsch, [7]Julius Popp, [8]Marcel Daamen, [9]Dominik Gorris, [10]Michael T Heneka, [11]Henning Boecker, [12]Hans J Biersack, [13]Wolfgang Maier, [14]Hans H Schild, [15]Michael Wagner, [16]Frank Jessen [Full author list]Neurology [curation]DOI: 10.1212/WNL.0B013E31826C1A8D
PubMed: 22914828
glucose [curation]2012-08-22
Predictors of institutionalisation in incident dementia--results of the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe study).[1]Melanie Luppa, [2]Steffi G. Riedel-Heller, [3]Janine Stein, [4]Hanna Leicht, [5]Hans-Helmut König, [6]Hendrik van den Bussche, [7]Wolfgang Maier, [8]Martin Scherer, [9]Horst Bickel, [10]Edelgard Mösch, [11]Jochen Werle, [12]Michael Pentzek, [13]Angela Fuchs, [14]Marion Eisele, [15]Frank Jessen, [16]Franziska Tebarth, [17]Birgitt Wiese, [18]Siegfried Weyerer, [19]AgeCoDe study group [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000339729
PubMed: 22759566
dementia [curation]2012-07-02
Effect of cardiovascular and metabolic disease on cognitive test performance and cognitive change in older adults.[1]Mirjam Köhler, [2]Matthias Kliegel, [3]Hanna Kaduszkiewicz, [4]Cadja Bachmann, [5]Birgitt Wiese, [6]Horst Bickel, [7]Edelgard Mösch, [8]Siegfried Weyerer, [9]Jochen Werle, [10]Angela Fuchs, [11]Michael Pentzek, [12]Hanna Leicht, [13]Hans-Helmut König, [14]Melanie Luppa, [15]Steffi G. Riedel-Heller, [16]Frank Jessen, [17]Wolfgang Maier, [18]Martin Scherer, [19]Michael Wagner, [20]Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe) study group [Full author list]Journal of the American Geriatrics Society [curation]DOI: 10.1111/J.1532-5415.2012.04032.X
PubMed: 22703453
metabolic disease [curation]2012-06-15
Association of amygdala volumes with cortisol secretion in unipolar depressed patients.[1]Anna Schuhmacher, [2]Rainald Mössner, [3]Frank Jessen, [4]Lukas Scheef, [5]Wolfgang Block, [6]Anna Christine Belloche, [7]Leonhard Lennertz, [8]Hanne Welper, [9]Susanne Höfels, [10]Ute Pfeiffer, [11]Michael Wagner, [12]Wolfgang Maier, [13]Sybille Schwab, [14]Astrid Zobel [Full author list]Psychiatry Research [curation]DOI: 10.1016/J.PSCYCHRESNS.2011.09.007
PubMed: 22698761
cortisol [curation]2012-05-01
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid[1]Desirée E C Smith, [2]Yvo M Smulders, [3]Henk J Blom, [4]Julius Popp, [5]Frank Jessen, [6]Alexander Semmler, [7]Melinda Farkas, [8]Michael Linnebank [Full author list]Clinical Chemistry and Laboratory Medicine [curation]DOI: 10.1515/CCLM-2012-0056
PubMed: 22962226
cerebrospinal fluid [curation]; folic acid [curation]2012-03-24
Genome-Wide Association Study of Vascular Dementia[1]Elisabeth M.C. Schrijvers, [2]Britta Schürmann, [3]Peter J. Koudstaal, [4]Hendrik van den Bussche, [5]Cornelia M. van Duijn, [6]Frank Hentschel, [7]Reinhard Heun, [8]Albert Hofman, [9]Frank Jessen, [10]Heike Kölsch, [11]Johannes Kornhuber, ... [Full author list]Stroke Journal [curation]DOI: 10.1161/STROKEAHA.111.628768
PubMed: 22116812
dementia [curation]; vascular dementia [curation]; genome-wide association study [curation]2012-02-01
The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease[1]Amy Gerrish, [2]Giancarlo Russo, [3]Alexander John Richards, [4]Valentina Escott-Price, [5]Dobril Ivanov, [6]Denise Harold, [7]Rebecca C Sims, [8]Richard Abraham, [9]Paul Hollingworth, [10]Jade Chapman, ..., [44]John Collinge, [45]Wolfgang Maier, [46]Frank Jessen, [47]Heike Kölsch, [48]Reinhard Heun, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110824
PubMed: 22027014
Alzheimer's disease [curation]2012-01-01
Cerebrospinal fluid soluble amyloid-β protein precursor as a potential novel biomarkers of Alzheimer's disease.[1]Piotr Lewczuk, [2]Julius Popp, [3]Natalia Lelental, [4]Heike Kölsch, [5]Wolfgang Maier, [6]Johannes Kornhuber, [7]Frank Jessen [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110857
PubMed: 21971403
cerebrospinal fluid [curation]; biomarker [curation]2012-01-01
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease[1]Sönke Arlt, [2]Edzard Schwedhelm, [3]Heike Kölsch, [4]Holger Jahn, [5]Michael Linnebank, [6]Yvo Smulders, [7]Frank Jessen, [8]Rainer H Böger, [9]Julius Popp [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2012-112138
PubMed: 22710910
cerebrospinal fluid [curation]2012-01-01
Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment[1]Lars Frings, [2]Stefan Klöppel, [3]Stefan J Teipel, [4]Olive Melissa Minor Peters, [5]Lutz Frölich, [6]Johannes Pantel, [7]Johannes Schröder, [8]Hermann-Josef Gertz, [9]Sönke Arlt, [10]Isabella Heuser, [11]Johannes Kornhuber, [12]Jens Wiltfang, [13]Wolfgang Maier, [14]Frank Jessen, [15]Harald Hampel, [16]Michael Hull [Full author list]Current Alzheimer Research [curation]DOI: 10.2174/156720511798192673
PubMed: 21592050
Alzheimer's disease [curation]; dementia [curation]; mild cognitive impairment [curation]2011-12-01
The future of Alzheimer's disease: the next 10 years[1]Harald Hampel, [2]David Prvulovic, [3]Stefan J Teipel, [4]Frank Jessen, [5]Christian Luckhaus, [6]Lutz Frölich, [7]Matthias W Riepe, [8]Richard Dodel, [9]Thomas Leyhe, [10]Lars Bertram, [11]Wolfgang Hoffmann, [12]Frank Faltraco, [13]German Task Force on Alzheimer's Disease (GTF-AD) [Full author list]Progress in Neurobiology [curation]DOI: 10.1016/J.PNEUROBIO.2011.11.008
PubMed: 22137045
Alzheimer's disease [curation]2011-11-22
Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study[1]Stefan J Teipel, [2]Sigrid Reuter, [3]Bram Stieltjes, [4]Julio Acosta-Cabronero, [5]Ulrike Ernemann, [6]Andreas Fellgiebel, [7]Massimo Filippi, [8]Giovanni B. Frisoni, [9]Frank Hentschel, [10]Frank Jessen, [11]Stefan Klöppel, [12]Thomas Meindl, [13]Petra Pouwels, [14]Karl-Heinz Hauenstein, [15]Harald Hampel [Full author list]Psychiatry Research [curation]DOI: 10.1016/J.PSCYCHRESNS.2011.05.012
PubMed: 22078796
diffusion tensor imaging [curation]2011-11-09
N-acetylaspartylglutamate (NAAG) and N-acetylaspartate (NAA) in patients with schizophrenia[1]Frank Jessen, [2]Natascha Fingerhut, [3]Alois M Sprinkart, [4]Kai-Uwe Kühn, [5]Nadine Petrovsky, [6]Wolfgang Maier, [7]Hans-H Schild, [8]Wolfgang Block, [9]Michael Wagner, [10]Frank Traeber [Full author list]Schizophrenia Bulletin [curation]DOI: 10.1093/SCHBUL/SBR127
PubMed: 21914645
schizophrenia [curation]2011-09-12
Long-Term Stability of Alzheimer's Disease Biomarker Proteins in Cerebrospinal Fluid[1]Carola G. Schipke, [2]Frank Jessen, [3]Stefan J Teipel, [4]Christian Luckhaus, [5]Jens Wiltfang, [6]Hermann Esselmann, [7]Lutz Frölich, [8]Wolfgang Maier, [9]Eckart Rüther, [10]Frank L. Heppner, [11]Stefan Prokop, [12]Isabella Heuser, [13]Oliver Peters [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110329
PubMed: 21606567
Alzheimer's disease [curation]; biomarker [curation]2011-09-09
Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes.[1]Stefan J Teipel, [2]Olive Melissa Minor Peters, [3]Isabella Heuser, [4]Frank Jessen, [5]Wolfgang Maier, [6]Lutz Froelich, [7]Sönke Arlt, [8]Michael Hull, [9]Hermann-Josef Gertz, [10]Johannes Kornhuber, [11]Jens Wiltfang, [12]Johannes Thome, [13]Otto Rienhoff, [14]Thomas Meindl, [15]Harald Hampel, [16]Michel J. Grothe [Full author list]World Journal of Biological Psychiatry [curation]DOI: 10.3109/15622975.2011.603222
PubMed: 21906007
multicenter clinical trial [curation]2011-09-01
Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation.[1]Markus P Kummer, [2]Michael Hermes, [3]Andrea Delekarte, [4]Thea Hammerschmidt, [5]Sathish Kumar, [6]Dick Terwel, [7]Jochen Walter, [8]Hans-Christian Pape, [9]Simone König, [10]Sigrun Roeber, [11]Frank Jessen, [12]Thomas Klockgether, [13]Martin Korte, [14]Michael T Heneka [Full author list]Neuron [curation]DOI: 10.1016/J.NEURON.2011.07.001
PubMed: 21903077
2011-09-01
Evidence of neuronal compensation during episodic memory in subjective memory impairment.[1]Susanne Erk, [2]Annika Spottke, [3]Alice Meisen, [4]Michael Wagner, [5]Henrik Walter, [6]Frank Jessen [Full author list]JAMA Psychiatry [curation]DOI: 10.1001/ARCHGENPSYCHIATRY.2011.80
PubMed: 21810648
episodic memory [curation]2011-08-01
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease[1]Paul Hollingworth, [2]Denise Harold, [3]Rebecca C Sims, [4]Amy Gerrish, [5]Jean-Charles Lambert, [6]Minerva M Carrasquillo, [7]Richard Abraham, [8]Marian L Hamshere, [9]Jaspreet Singh Pahwa, [10]Valentina Escott-Price, ..., [47]John Collinge, [48]Wolfgang Maier, [49]Frank Jessen, [50]Eckart Rüther, [51]Britta Schürmann, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG.803
PubMed: 21460840
Alzheimer's disease [curation]2011-04-03
Prediction of dementia in primary care patients[1]Frank Jessen, [2]Birgitt Wiese, [3]Horst Bickel, [4]Sandra Eiffländer-Gorfer, [5]Angela Fuchs, [6]Hanna Kaduszkiewicz, [7]Mirjam Köhler, [8]Tobias Luck, [9]Edelgard Mösch, [10]Michael Pentzek, [11]Steffi G. Riedel-Heller, [12]Michael Wagner, [13]Siegfried Weyerer, [14]Wolfgang Maier, [15]Hendrik van den Bussche, [16]AgeCoDe Study Group [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0016852
PubMed: 21364746
dementia [curation]2011-02-18
Correction: Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease[1]Lesley Jones, [2]Peter Holmans, [3]Marian L. Hamshere, [4]Denise Harold, [5]Valentina Moskvina, [6]Dobril Ivanov, [7]Andrew Pocklington, [8]Richard Abraham, [9]Paul Hollingworth, [10]Rebecca Sims, ..., [39]John Collinge, [40]Wolfgang Maier, [41]Frank Jessen, [42]Britta Schürmann, [43]Hendrik van den Bussche, ... [Full author list]PLOS One [curation]DOI: 10.1371/ANNOTATION/A0BB886D-D345-4A20-A82E-ADCE9B047798
2011-02-11
A multicentre RCT on community occupational therapy in Alzheimer's disease: 10 sessions are not better than one consultation[1]Sebastian Voigt-Radloff, [2]Maud Graff, [3]Rainer Leonhart, [4]Katrin Schornstein, [5]Frank Jessen, [6]Jens Bohlken, [7]Brigitte Metz, [8]Andreas Fellgiebel, [9]Richard Dodel, [10]Gerhard Eschweiler, [11]Myrra Vernooij-Dassen, [12]Marcel Olde Rikkert, [13]Michael Hüll [Full author list]BMJ Open [curation]DOI: 10.1136/BMJOPEN-2011-000096
PubMed: 22021760
Alzheimer's disease [curation]; multicenter clinical trial [curation]2011-01-01
Cost and care of patients with Alzheimer's disease: clinical predictors in German health care settings[1]Jens Peter Reese, [2]Philipp Hessmann, [3]Greta Seeberg, [4]Dajana Henkel, [5]Pamela Hirzmann, [6]Jürgen Rieke, [7]Erika Baum, [8]Frank Dannhoff, [9]Matthias J Müller, [10]Frank Jessen, [11]Monika-Balzer Geldsetzer, [12]Richard Dodel [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110539
PubMed: 21876256
Alzheimer's disease [curation]2011-01-01
Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia.[1]Frank Jessen, [2]Piotr Lewczuk, [3]Okan Gür, [4]Wolfgang Block, [5]Gabriele Ende, [6]Lutz Frölich, [7]Thilo Hammen, [8]Sönke Arlt, [9]Johannes Kornhuber, [10]Thomas Kucinski, [11]Julius Popp, [12]Olive Melissa Minor Peters, [13]Wolfgang Maier, [14]Frank Traeber, [15]Jens Wiltfang [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110398
PubMed: 21841259
cerebrospinal fluid [curation]2011-01-01
Association of the Alzheimer's disease clusterin risk allele with plasma clusterin concentration.[1]Britta Schürmann, [2]Birgitt Wiese, [3]Horst Bickel, [4]Siegfried Weyerer, [5]Steffi G. Riedel-Heller, [6]Michael Pentzek, [7]Cadja Bachmann, [8]Julie Williams, [9]Hendrik van den Bussche, [10]Wolfgang Maier, [11]Frank Jessen [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2011-110251
PubMed: 21422520
Alzheimer's disease [curation]2011-01-01
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease[1]Lesley Jones, [2]Peter Holmans, [3]Marian L Hamshere, [4]Denise Harold, [5]Valentina Escott-Price, [6]Dobril Ivanov, [7]Andrew Pocklington, [8]Richard Abraham, [9]Paul Hollingworth, [10]Rebecca C Sims, ..., [39]John Collinge, [40]Wolfgang Maier, [41]Frank Jessen, [42]Britta Schürmann, [43]Reinhard Heun, ... [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0013950
PubMed: 21085570
Alzheimer's disease [curation]2010-11-15
Anticholinergic drug use and risk for dementia: target for dementia prevention.[1]Frank Jessen, [2]Hanna Kaduszkiewicz, [3]Moritz Daerr, [4]Horst Bickel, [5]Michael Pentzek, [6]Steffi G. Riedel-Heller, [7]Michael Wagner, [8]Siegfried Weyerer, [9]Birgitt Wiese, [10]Hendrik van den Bussche, [11]Karl Broich, [12]Wolfgang Maier [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-010-0156-4
PubMed: 20960005
dementia [curation]; prevention [curation]2010-10-20
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives[1]Harald Hampel, [2]Richard Frank, [3]Karl Broich, [4]Stefan J Teipel, [5]Russell G Katz, [6]John Anthony Hardy, [7]Karl Herholz, [8]Arun L W Bokde, [9]Frank Jessen, [10]Yvonne C Hoessler, [11]Wendy R Sanhai, [12]Henrik Zetterberg, [13]Janet Woodcock, [14]Kaj Blennow [Full author list]Nature Reviews Drug Discovery [curation]DOI: 10.1038/NRD3115
PubMed: 20592748
Alzheimer's disease [curation]; biomarker [curation]2010-07-01
S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease[1]Michael Linnebank, [2]Julius Popp, [3]Yvo Smulders, [4]Desiree Smith, [5]Alexander Semmler, [6]Melinda Farkas, [7]Luka Kulic, [8]Gabriela Cvetanovska, [9]Henk J Blom, [10]Birgit Stoffel-Wagner, [11]Heike Kölsch, [12]Michael Weller, [13]Frank Jessen [Full author list]Neurodegenerative Diseases [curation]DOI: 10.1159/000309657
PubMed: 20523031
Alzheimer's disease [curation]; cerebrospinal fluid [curation]2010-06-03
Evidence for an association between KIBRA and late-onset Alzheimer's disease[1]Jason J Corneveaux, [2]Winnie S Liang, [3]Eric M. Reiman, [4]Jennifer A Webster, [5]Amanda J Myers, [6]Victoria L Zismann, [7]Keta D Joshipura, [8]John V Pearson, [9]Diane Hu-Lince, [10]David W Craig, ..., [21]Jan O Aasly, [22]Reinhard Heun, [23]Frank Jessen, [24]Heike Kölsch, [25]Joseph Rogers, ... [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2008.07.014
PubMed: 18789830
Alzheimer's disease [curation]2010-06-01
Resting-state perfusion in nonmedicated schizophrenic patients: a continuous arterial spin-labeling 3.0-T MR study[1]Lukas Scheef, [2]Christoph Manka, [3]Marcel Daamen, [4]Kai-Uwe Kühn, [5]Wolfgang Maier, [6]Hans H Schild, [7]Frank Jessen [Full author list]Radiology [curation]DOI: 10.1148/RADIOL.10091224
PubMed: 20505069
schizophrenia [curation]; patient [curation]2010-05-26
Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease[1]Stefan J Teipel, [2]Michael Ewers, [3]Stefanie Wolf, [4]Frank Jessen, [5]Heike Kölsch, [6]Sönke Arlt, [7]Christian Luckhaus, [8]Peter Schönknecht, [9]Klaus Schmidtke, [10]Isabella Heuser, [11]Lutz Frölich, [12]Gabriele Ende, [13]Johannes Pantel, [14]Jens Wiltfang, [15]Fabian Rakebrandt, [16]Olive Melissa Minor Peters, [17]Christine Born, [18]Johannes Kornhuber, [19]Harald Hampel [Full author list]Psychiatry Research [curation]DOI: 10.1016/J.PSCYCHRESNS.2010.03.003
PubMed: 20493672
Alzheimer's disease [curation]2010-05-20
Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment[1]Frank Jessen, [2]Birgitt Wiese, [3]Cadja Bachmann, [4]Sandra Eifflaender-Gorfer, [5]Franziska Haller, [6]Heike Kölsch, [7]Tobias Luck, [8]Edelgard Mösch, [9]Hendrik van den Bussche, [10]Michael Wagner, [11]Anja Wollny, [12]Thomas Zimmermann, [13]Michael Pentzek, [14]Steffi G. Riedel-Heller, [15]Heinz-Peter Romberg, [16]Siegfried Weyerer, [17]Hanna Kaduszkiewicz, [18]Wolfgang Maier, [19]Horst Bickel, [20]German Study on Aging, Cognition and Dementia in Primary Care Patients Study Group [Full author list]JAMA Psychiatry [curation]DOI: 10.1001/ARCHGENPSYCHIATRY.2010.30
PubMed: 20368517
dementia [curation]; cognitive dysfunction [curation]2010-04-01
Alterations of cholesterol precursor levels in Alzheimer's disease[1]Heike Kölsch, [2]Reinhard Heun, [3]Frank Jessen, [4]Julius Popp, [5]Frank Hentschel, [6]Wolfgang Maier, [7]Dieter Lütjohann [Full author list]Biochimica et Biophysica Acta [curation]DOI: 10.1016/J.BBALIP.2010.03.001
PubMed: 20226877
Alzheimer's disease [curation]2010-03-11
The role of macrophage migration inhibitory factor in Alzheimer's disease[1]Michael Bacher, [2]Oliver Deuster, [3]Bayan Aljabari, [4]Rupert Egensperger, [5]Frauke Neff, [6]Frank Jessen, [7]Julius Popp, [8]Carmen Noelker, [9]Jens Peter Reese, [10]Yousef Al-Abed, [11]Richard Dodel [Full author list]Molecular Medicine [curation]DOI: 10.2119/MOLMED.2009.00123
PubMed: 20200619
Alzheimer's disease [curation]; macrophage [curation]2010-03-01
Volume loss of the medial temporal lobe structures in subjective memory impairment.[1]Nadine Striepens, [2]Lukas Scheef, [3]Andrea Wind, [4]Julius Popp, [5]Annika Spottke, [6]Déirdre Cooper-Mahkorn, [7]Husam Suliman, [8]Michael Wagner, [9]Hans H Schild, [10]Frank Jessen [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000264630
PubMed: 20110703
2010-01-28
DNA sequence variants of the FKBP5 gene are associated with unipolar depression[1]Astrid Zobel, [2]Anna Schuhmacher, [3]Frank Jessen, [4]Susanne Höfels, [5]Olrik von Widdern, [6]Martin Metten, [7]Ute Pfeiffer, [8]Claudia Hanses, [9]Tim Becker, [10]Marcella Rietschel, [11]Lukas Scheef, [12]Wolfgang Block, [13]Hans H Schild, [14]Wolfgang Maier, [15]Sibylle G Schwab [Full author list]The International Journal of Neuropsychopharmacology [curation]DOI: 10.1017/S1461145709991155
PubMed: 20047716
2010-01-05
Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype[1]Julius Popp, [2]Piotr Lewczuk, [3]Ingo Frommann, [4]Heike Kölsch, [5]Johannes Kornhuber, [6]Wolfgang Maier, [7]Frank Jessen [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2010-100561
PubMed: 21084733
Alzheimer's disease [curation]; cerebrospinal fluid [curation]; lifetime [curation]2010-01-01
Apart from nihilism and stigma: what influences general practitioners' accuracy in identifying incident dementia?[1]Michael Pentzek, [2]Anja Wollny, [3]Birgitt Wiese, [4]Frank Jessen, [5]Franziska Haller, [6]Wolfgang Maier, [7]Steffi G. Riedel-Heller, [8]Matthias C Angermeyer, [9]Horst Bickel, [10]Edelgard Mösch, [11]Siegfried Weyerer, [12]Jochen Werle, [13]Cadja Bachmann, [14]Thomas Zimmermann, [15]Hendrik van den Bussche, [16]Heinz-Harald Abholz, [17]Angela Fuchs, [18]AgeCoDe Study Group [Full author list]American Journal of Geriatric Psychiatry [curation]DOI: 10.1097/JGP.0B013E3181B2075E
PubMed: 20104054
2009-11-01
Is the clock drawing test appropriate for screening for mild cognitive impairment?--Results of the German study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe).[1]Lena Ehreke, [2]Melanie Luppa, [3]Tobias Luck, [4]Birgitt Wiese, [5]Siegfried Weyerer, [6]Sandra Eifflaender-Gorfer, [7]Dagmar Weeg, [8]Julia Olbrich, [9]Hendrik van den Bussche, [10]Cadja Bachmann, [11]Marion Eisele, [12]Wolfgang Maier, [13]Frank Jessen, [14]Michael Wagner, [15]Angela Fuchs, [16]Michael Pentzek, [17]Matthias C Angermeyer, [18]Hans-Helmut König, [19]Steffi G. Riedel-Heller, [20]AgeCoDe group [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000253484
PubMed: 19887799
dementia [curation]; mild cognitive impairment [curation]2009-10-30
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease[1]Denise Harold, [2]Richard Abraham, [3]Paul Hollingworth, [4]Rebecca C Sims, [5]Amy Gerrish, [6]Marian L Hamshere, [7]Jaspreet Singh Pahwa, [8]Valentina Escott-Price, [9]Kimberley Dowzell, [10]Amy Williams, ..., [39]John Collinge, [40]Wolfgang Maier, [41]Frank Jessen, [42]Britta Schürmann, [43]Reinhard Heun, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG.440
PubMed: 19734902
Alzheimer's disease [curation]; genome-wide association study [curation]2009-10-01
Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease[1]Denise Harold, [2]Richard Abraham, [3]Paul Hollingworth, [4]Rebecca Sims, [5]Amy Gerrish, [6]Marian L Hamshere, [7]Jaspreet Singh Pahwa, [8]Valentina Escott-Price, [9]Kimberley Dowzell, [10]Amy Williams, ..., [39]John Collinge, [40]Wolfgang Maier, [41]Frank Jessen, [42]Britta Schürmann, [43]Hendrik van den Bussche, ... [Full author list]Nature Genetics [curation]DOI: 10.1038/NG1009-1156D
genome-wide association study [curation]; Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease [curation]2009-10-01
Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis[1]Jennifer Webster, [2]Eric M. Reiman, [3]Victoria L Zismann, [4]Keta D Joshipura, [5]John V Pearson, [6]Diane Hu-Lince, [7]Matthew J Huentelman, [8]David W Craig, [9]Keith D Coon, [10]Thomas G Beach, ..., [19]Joseph Rogers, [20]Reinhard Heun, [21]Frank Jessen, [22]Heike Kölsch, [23]Christopher B Heward, ... [Full author list]International journal of molecular epidemiology and genetics [curation]PubMed: 21537449Alzheimer's disease [curation]; risk factor [curation]; whole genome sequencing [curation]2009-07-26
Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly.[1]Heike Kölsch, [2]Michael Wagner, [3]Andras Bilkei-Gorzó, [4]Mohammad Reza Toliat, [5]Michael Pentzek, [6]Angela Fuchs, [7]Hanna Kaduszkiewicz, [8]Hendrik van den Bussche, [9]Steffi G. Riedel-Heller, [10]Matthias C Angermeyer, [11]Siegfried Weyerer, [12]Jochen Werle, [13]Horst Bickel, [14]Edelgard Mösch, [15]Birgitt Wiese, [16]Moritz Daerr, [17]Frank Jessen, [18]Wolfgang Maier, [19]Martin Dichgans [Full author list]Journal of Neural Transmission [curation]DOI: 10.1007/S00702-009-0238-5
PubMed: 19468819
episodic memory [curation]2009-05-26
Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer's disease[1]Julius Popp, [2]Michael Bacher, [3]Heike Kölsch, [4]Carmen Noelker, [5]Oliver Deuster, [6]Richard Dodel, [7]Frank Jessen [Full author list]Journal of Psychiatric Research [curation]DOI: 10.1016/J.JPSYCHIRES.2008.10.006
PubMed: 19038405
Alzheimer's disease [curation]; macrophage [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2009-05-01
Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network[1]Johannes Kornhuber, [2]Klaus Schmidtke, [3]Lutz Frölich, [4]Robert Perneczky, [5]Stefanie Wolf, [6]Harald Hampel, [7]Frank Jessen, [8]Isabella Heuser, [9]Olive Melissa Minor Peters, [10]Markus Weih, ... [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000210388
PubMed: 19339779
dementia [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2009-04-01
No association of the Val66Met polymorphism of the brain-derived neurotrophic factor with hippocampal volume in major depression[1]Frank Jessen, [2]Anna Schuhmacher, [3]Ole von Widdern, [4]Vera Guttenthaler, [5]Susanne Hofels, [6]Husam Suliman, [7]Lukas Scheef, [8]Wolfgang Block, [9]Horst Urbach, [10]Wolfgang Maier, [11]Astrid Zobel [Full author list]Psychiatric Genetics [curation]DOI: 10.1097/YPG.0B013E32832080CE
PubMed: 19668114
2009-04-01
Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.[1]Panagiotis Alexopoulos, [2]Florian Günther, [3]Julius Popp, [4]Frank Jessen, [5]Olive Melissa Minor Peters, [6]Stefanie Wolf, [7]Thomas Kneib, [8]Alexander Kurz, [9]Tanja Richter-Schmidinger, [10]Piotr Lewczuk, [11]Stefan Bleich, [12]Jens Wiltfang, [13]Johannes Kornhuber [Full author list]Journal of the American Geriatrics Society [curation]DOI: 10.1111/J.1532-5415.2009.02212.X
PubMed: 19405180
cerebrospinal fluid [curation]; biomarker [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2009-04-01
CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism[1]Heike Kölsch, [2]Dieter Lütjohann, [3]Frank Jessen, [4]Julius Popp, [5]Frank Hentschel, [6]Peter Kelemen, [7]Sandra Schmitz, [8]Wolfgang Maier, [9]Reinhard Heun [Full author list]European Psychiatry [curation]DOI: 10.1016/J.EURPSY.2008.12.005
PubMed: 19286353
Alzheimer's disease [curation]2009-03-16
RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism[1]Heike Kölsch, [2]Dieter Lütjohann, [3]Frank Jessen, [4]Julius Popp, [5]Frank Hentschel, [6]Peter Kelemen, [7]Silvia Friedrichs, [8]T A Wolfgang Maier, [9]Reinhard Heun [Full author list]Journal of Cellular and Molecular Medicine [curation]DOI: 10.1111/J.1582-4934.2009.00383.X
PubMed: 19374686
cell biology [curation]; Alzheimer's disease [curation]; signaling receptor activity [curation]; Retinoid X receptor alpha [curation]2009-03-01
Association of SORL1 gene variants with Alzheimer's disease[1]Heike Kölsch, [2]Frank Jessen, [3]Jens Wiltfang, [4]Piotr Lewczuk, [5]Martin Dichgans, [6]Stefan J Teipel, [7]Johannes Kornhuber, [8]Lutz Frölich, [9]Isabella Heuser, [10]Olive Melissa Minor Peters, [11]Birgitt Wiese, [12]Hanna Kaduszkiewicz, [13]Hendrik van den Bussche, [14]Michael Hull, [15]Alexander Kurz, [16]Eckhart Rüther, [17]Fritz Henn, [18]Wolfgang Maier [Full author list]Brain Research [curation]DOI: 10.1016/J.BRAINRES.2009.01.044
PubMed: 19368828
Alzheimer's disease [curation]2009-02-03
Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form[1]Hans-Wolfgang Klafki, [2]Piotr Lewczuk, [3]Heike Kamrowski-Kruck, [4]Juan Manuel Maler, [5]Katharina Müller, [6]Olive Melissa Minor Peters, [7]Isabella Heuser, [8]Frank Jessen, [9]Julius Popp, [10]Lutz Frölich, ... [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2009-1167
PubMed: 19625747
2009-01-01
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease[1]Julius Popp, [2]Piotr Lewczuk, [3]Michael Linnebank, [4]Gabriela Cvetanovska, [5]Yvo Smulders, [6]Heike Kölsch, [7]Ingo Frommann, [8]Johannes Kornhuber, [9]Wolfgang Maier, [10]Frank Jessen [Full author list]Journal of Alzheimer's Disease [curation]DOI: 10.3233/JAD-2009-1187
PubMed: 19661622
cerebrospinal fluid [curation]2009-01-01
Proton MR spectroscopy of the hippocampus at 3 T in patients with unipolar major depressive disorder: correlates and predictors of treatment response[1]Wolfgang Block, [2]Frank Träber, [3]Olrik von Widdern, [4]Martin Metten, [5]Hans Schild, [6]Wolfgang Maier, [7]Astrid Zobel, [8]Frank Jessen [Full author list]The International Journal of Neuropsychopharmacology [curation]DOI: 10.1017/S1461145708009516
PubMed: 18845018
major depressive disorder [curation]; patient [curation]; spectroscopy [curation]2008-10-10
Hippocampal surface analysis in subjective memory impairment, mild cognitive impairment and Alzheimer's dementia[1]Ralf Tepest, [2]Lei Wang, [3]John G Csernansky, [4]Philip Neubert, [5]Reinhard Heun, [6]Lukas Scheef, [7]Frank Jessen [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000161057
PubMed: 18841017
Alzheimer's disease [curation]; dementia [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2008-10-08
Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene[1]Astrid Zobel, [2]Frank Jessen, [3]Olrik von Widdern, [4]Anna Schuhmacher, [5]Susanne Höfels, [6]Martin Metten, [7]Marcella Rietschel, [8]Lukas Scheef, [9]Wolfgang Block, [10]Tim Becker, [11]Hans H Schild, [12]Wolfgang Maier, [13]Sibylle G Schwab [Full author list]American Journal of Medical Genetics Part B: Neuropsychiatric Genetics [curation]DOI: 10.1002/AJMG.B.30709
PubMed: 18286599
unipolar depression [curation]2008-09-01
CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk[1]Homeira Qureischie, [2]Reinhard Heun, [3]Dieter Lütjohann, [4]Julius Popp, [5]Frank Jessen, [6]Christine Ledschbor-Frahnert, [7]Holger Thiele, [8]Wolfgang Maier, [9]Frank Hentschel, [10]Peter Kelemen, [11]Heike Kölsch [Full author list]Brain Research [curation]DOI: 10.1016/J.BRAINRES.2008.07.047
PubMed: 18680734
Alzheimer's disease [curation]2008-07-22
Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease.[1]Heike Kölsch, [2]Frank Jessen, [3]Jens Wiltfang, [4]Piotr Lewczuk, [5]Martin Dichgans, [6]Johannes Kornhuber, [7]Lutz Frölich, [8]Isabella Heuser, [9]Olive Melissa Minor Peters, [10]Jörg B. Schulz, [11]Sibylle G Schwab, [12]Wolfgang Maier [Full author list]Neuroscience Letters [curation]DOI: 10.1016/J.NEULET.2008.05.049
PubMed: 18541377
Alzheimer's disease [curation]2008-05-18
Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older[1]Siegfried Weyerer, [2]Sandra Eifflaender-Gorfer, [3]Leonore Köhler, [4]Frank Jessen, [5]Wolfgang Maier, [6]Angela Fuchs, [7]Michael Pentzek, [8]Hanna Kaduszkiewicz, [9]Cadja Bachmann, [10]Matthias C Angermeyer, [11]Melanie Luppa, [12]Birgitt Wiese, [13]Edelgard Mösch, [14]Horst Bickel, [15]German AgeCoDe Study group (German Study on Ageing, Cognition and Dementia in Primary Care Patients) [Full author list]Journal of Affective Disorders [curation]DOI: 10.1016/J.JAD.2008.02.008
PubMed: 18372049
2008-03-26
Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain[1]Ullrich Wüllner, [2]Daniela Gündisch, [3]Hans Herzog, [4]Martina Minnerop, [5]Alexis Joe, [6]Marc Warnecke, [7]Frank Jessen, [8]Christian Schütz, [9]Michael Reinhardt, [10]Wolfgang Eschner, [11]Thomas Klockgether, [12]Joern Schmaljohann [Full author list]Neuroscience Letters [curation]DOI: 10.1016/J.NEULET.2007.10.011
PubMed: 17997038
2007-10-22
Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe)[1]Tobias Luck, [2]Steffi G. Riedel-Heller, [3]Hanna Kaduszkiewicz, [4]Horst Bickel, [5]Frank Jessen, [6]Michael Pentzek, [7]Birgitt Wiese, [8]Heike Koelsch, [9]Hendrik van den Bussche, [10]Heinz-Harald Abholz, [11]Edelgard Moesch, [12]Sandra Eifflaender-Gorfer, [13]Matthias C Angermeyer, [14]Wolfgang Maier, [15]Siegfried Weyerer, [16]AgeCoDe group [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000108099
PubMed: 17848793
dementia [curation]; mild cognitive impairment [curation]; cognitive dysfunction [curation]2007-09-11
CSF cortisol in Alzheimer's disease and mild cognitive impairment[1]Julius Popp, [2]Karsten Schaper, [3]Heike Kölsch, [4]Gabriela Cvetanovska, [5]Fatima Rommel, [6]Dietrich Klingmüller, [7]Richard Dodel, [8]Ullrich Wüllner, [9]Frank Jessen [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2007.07.007
PubMed: 17716786
Alzheimer's disease [curation]; cortisol [curation]; mild cognitive impairment [curation]2007-08-22
Patterns of subjective memory impairment in the elderly: association with memory performance[1]Frank Jessen, [2]Birgitt Wiese, [3]Gabriela Cvetanovska, [4]Angela Fuchs, [5]Hanna Kaduszkiewicz, [6]Heike Kölsch, [7]Tobias Luck, [8]Edelgard Mösch, [9]Michael Pentzek, [10]Steffi G. Riedel-Heller, [11]Jochen Werle, [12]Siegfried Weyerer, [13]Thomas Zimmermann, [14]Wolfgang Maier, [15]Horst Bickel [Full author list]Psychological Medicine [curation]DOI: 10.1017/S0033291707001122
PubMed: 17623488
2007-07-11
Histologically confirmed amyloid deposition and low CSF Abeta42 in a cognitively normal subject.[1]Julius Popp, [2]Dietmar R. Thal, [3]Piotr Lewczuk, [4]Jens Wiltfang, [5]Frank Jessen [Full author list]Journal of Neurology [curation]DOI: 10.1007/S00415-006-0445-Z
PubMed: 17361344
2007-03-14
Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load.[1]Jens Wiltfang, [2]Hermann Esselmann, [3]Mirko Bibl, [4]Michael Hull, [5]Harald Hampel, [6]Holger Kessler, [7]Lutz Frölich, [8]Johannes Schröder, [9]Olive Melissa Minor Peters, [10]Frank Jessen, [11]Christian Luckhaus, [12]Robert Perneczky, [13]Holger Jahn, [14]Magdalena Fiszer, [15]Juan Manuel Maler, [16]Rüdiger Zimmermann, [17]Ralf Bruckmoser, [18]Johannes Kornhuber, [19]Piotr Lewczuk [Full author list]Journal of Neurochemistry [curation]DOI: 10.1111/J.1471-4159.2006.04404.X
PubMed: 17254013
patient [curation]2007-01-24
Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.[1]Piotr Lewczuk, [2]Johannes Kornhuber, [3]Hugo Vanderstichele, [4]Eugeen Vanmechelen, [5]Hermann Esselmann, [6]Mirko Bibl, [7]Stefanie Wolf, [8]Markus Otto, [9]Udo Reulbach, [10]Heike Kölsch, [11]Frank Jessen, [12]Johannes Schröder, [13]Peter Schönknecht, ... [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2006.12.010
PubMed: 17239996
dementia [curation]; patient [curation]; biomarker [curation]2007-01-19
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies[1]John V Pearson, [2]Matthew J Huentelman, [3]Rebecca F Halperin, [4]Waibhav D Tembe, [5]Stacey Melquist, [6]Nils Homer, [7]Marcel Brun, [8]Szabolcs Szelinger, [9]Keith D Coon, [10]Victoria L Zismann, ..., [14]Jan O Aasly, [15]Reinhard Heun, [16]Frank Jessen, [17]Heike Kolsch, [18]Magdalini Tsolaki, ... [Full author list]American Journal of Human Genetics [curation]DOI: 10.1086/510686
PubMed: 17160900
single-nucleotide polymorphism [curation]2006-12-06
PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease.[1]Julia Holzapfel, [2]Reinhard Heun, [3]Dieter Lütjohann, [4]Frank Jessen, [5]Wolfgang Maier, [6]Heike Kölsch [Full author list]Neuroscience Letters [curation]DOI: 10.1016/J.NEULET.2006.08.029
PubMed: 16979821
risk factor [curation]2006-09-18
Proton magnetic resonance spectroscopy in subjects at risk for schizophrenia[1]Frank Jessen, [2]Harald Scherk, [3]Frank Traeber, [4]Sonja Theyson, [5]Julia Berning, [6]Ralf Tepest, [7]Peter Falkai, [8]Hans-H Schild, [9]Wolfgang Maier, [10]Michael Wagner, [11]Wolfgang Block [Full author list]Schizophrenia Research [curation]DOI: 10.1016/J.SCHRES.2006.06.011
PubMed: 16842971
schizophrenia [curation]2006-07-13
Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease[1]Heike Kölsch, [2]Dieter Lütjohann, [3]Frank Jessen, [4]Klaus Von Bergmann, [5]Sandra Schmitz, [6]Horst Urbach, [7]Wolfgang Maier, [8]Reinhard Heun [Full author list]International Journal of Molecular Medicine [curation]PubMed: 16596262Alzheimer's disease [curation]; risk factor [curation]2006-05-01
Memory deficits in abstinent MDMA (ecstasy) users: neuropsychological evidence of frontal dysfunction.[1]Boris B Quednow, [2]Frank Jessen, [3]Kai-Uwe Kuhn, [4]Wolfgang Maier, [5]Irene Daum, [6]Michael Wagner [Full author list]Journal of Psychopharmacology [curation]DOI: 10.1177/0269881106061200
PubMed: 16574711
neuropsychology [curation]2006-05-01
A multicenter reproducibility study of single-voxel 1H-MRS of the medial temporal lobe[1]Frank Traeber, [2]Wolfgang Block, [3]Nikolaus Freymann, [4]Okan Gür, [5]Thomas Kucinski, [6]Thilo Hammen, [7]Gabriele Ende, [8]Ulrich Pilatus, [9]Harald Hampel, [10]Hans H Schild, [11]Reinhard Heun, [12]Frank Jessen [Full author list]European Radiology [curation]DOI: 10.1007/S00330-005-0108-Y
PubMed: 16416279
reproducibility [curation]; multicenter clinical trial [curation]2006-01-17
Volume reduction of the entorhinal cortex in subjective memory impairment[1]Frank Jessen, [2]Ludger Feyen, [3]Katrin Freymann, [4]Ralf Tepest, [5]Wolfgang Maier, [6]Reinhard Heun, [7]Hans-H Schild, [8]Lukas Scheef [Full author list]Neurobiology of Aging [curation]DOI: 10.1016/J.NEUROBIOLAGING.2005.10.010
PubMed: 16309795
entorhinal cortex [curation]2005-11-23
APOA1 polymorphism influences risk for early-onset nonfamiliar AD[1]Heike Vollbach, [2]Reinhard Heun, [3]Chris M Morris, [4]Jim A Edwardson, [5]Ian G McKeith, [6]Frank Jessen, [7]Anne Schulz, [8]Wolfgang Maier, [9]Heike Kölsch [Full author list]Annals of Neurology [curation]DOI: 10.1002/ANA.20593
PubMed: 16130094
2005-09-01
A comparative study of the different N-acetylaspartate measures of the medial temporal lobe in Alzheimer's disease[1]Frank Jessen, [2]Frank Traeber, [3]Nikolaus Freymann, [4]Wolfgang Maier, [5]Hans-H Schild, [6]Reinhard Heun, [7]Wolfgang Block [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000087095
PubMed: 16024934
Alzheimer's disease [curation]2005-07-15
Risk factors and early signs of Alzheimer's disease in a family study sample. Risk of AD.[1]Reinhard Heun, [2]Heike Kölsch, [3]Frank Jessen [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-005-0596-4
PubMed: 15895300
Alzheimer's disease [curation]2005-05-20
Differences of cerebral activation between superior and inferior learners during motor sequence encoding and retrieval.[1]Reinhard Heun, [2]Nikolaus Freymann, [3]Dirk Oliver Granath, [4]Christian Paul Stracke, [5]Frank Jessen, [6]Katrin Barkow, [7]Jürgen Reul [Full author list]Psychiatry Research [curation]DOI: 10.1016/J.PSCYCHRESNS.2004.01.007
PubMed: 15546700
2004-11-01
Contribution of apolipoprotein E and cathepsin D genotypes to the familial aggregation of Alzheimer's disease[1]Reinhard Heun, [2]Ursula Ptok, [3]Heike Kölsch, [4]Wolfgang Maier, [5]Frank Jessen [Full author list]Dementia and Geriatric Cognitive Disorders [curation]DOI: 10.1159/000079195
PubMed: 15211070
Alzheimer's disease [curation]2004-06-18
Reduced hippocampal activation during encoding and recognition of words in schizophrenia patients[1]Frank Jessen, [2]Lukas Scheef, [3]Lars Germeshausen, [4]Youlha Tawo, [5]Martin Kockler, [6]Kai-Uwe Kuhn, [7]Wolfgang Maier, [8]Hans H Schild, [9]Reinhard Heun [Full author list]American Journal of Psychiatry [curation]DOI: 10.1176/APPI.AJP.160.7.1305
PubMed: 12832246
schizophrenia [curation]2003-07-01
Association of an interleukin-1beta gene polymorphism at position -511 with Alzheimer's disease.[1]Christian Ehl, [2]Heike Kölsch, [3]Ursula Ptok, [4]Frank Jessen, [5]Sandra Schmitz, [6]Christine Frahnert, [7]Ralf G. Schlösser, [8]Marie Luise Rao, [9]Wolfgang Maier, [10]Reinhard Heun [Full author list]International Journal of Molecular Medicine [curation]PubMed: 12525884Alzheimer's disease [curation]2003-02-01
Lifetime depressive and somatic symptoms as preclinical markers of late-onset depression.[1]Sandra Hein, [2]Marzia Bonsignore, [3]Katrin Barkow, [4]Frank Jessen, [5]Ursula Ptok, [6]Reinhard Heun [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-003-0399-4
PubMed: 12664308
2003-02-01
Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease. Results of a pilot study.[1]Metin Bagli, [2]Andreas Papassotiropoulos, [3]Harald Hampel, [4]Karin Becker, [5]Frank Jessen, [6]Katharina Bürger, [7]U Ptok, [8]Marie Luise Rao, [9]Hans-Jürgen Möller, [10]Wolfgang Maier, [11]Reinhard Heun [Full author list]European Archives of Psychiatry and Clinical Neuroscience [curation]DOI: 10.1007/S00406-003-0405-X
PubMed: 12664314
interleukins [curation]2003-02-01
Novelty detection and repetition suppression in a passive picture viewing task: a possible approach for the evaluation of neuropsychiatric disorders.[1]Frank Jessen, [2]Christoph Manka, [3]Lukas Scheef, [4]Dirk-Oliver Granath, [5]Hans H Schild, [6]Reinhard Heun [Full author list]Human Brain Mapping [curation]DOI: 10.1002/HBM.10071
PubMed: 12395390
2002-12-01
Cerebrospinal fluid levels of beta-amyloid(42) in patients with Alzheimer's disease are related to the exon 2 polymorphism of the cathepsin D gene[1]Andreas Papassotiropoulos, [2]Huw D Lewis, [3]Metin Bagli, [4]Frank Jessen, [5]Ursula Ptok, [6]Andrea Schulte, [7]Mark S Shearman, [8]Reinhard Heun [Full author list]NeuroReport [curation]DOI: 10.1097/00001756-200207190-00015
PubMed: 12151789
Alzheimer's disease [curation]; cerebrospinal fluid [curation]2002-07-01
Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer disease[1]Wolfgang Block, [2]Frank Jessen, [3]Frank Träber, [4]Sebastian Flacke, [5]Christoph Manka, [6]Rolf Lamerichs, [7]Ewald Keller, [8]Reinhard Heun, [9]Hans Schild [Full author list]Archives of Neurology [curation]DOI: 10.1001/ARCHNEUR.59.5.828
PubMed: 12020267
Alzheimer's disease [curation]2002-05-01
Correct Q number of author item for selected works.
NO replacement author: revert to author name strings

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