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Lea M Delbridge

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Listed Publications

46 publications found

TitleAuthors (identified)Published InIdentifier(s)TopicPublished Date
High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice.[1]Sarah E Heywood, [2]Adele L Richart, [3]Darren C Henstridge, [4]Karen Alt, [5]Helen Kiriazis, [6]Claire Zammit, [7]Andrew L Carey, [8]Helene L Kammoun, [9]Lea M Delbridge, [10]Medini Reddy, [11]Yi-Ching Chen, [12]Xiao-Jun Du, [13]Christoph E. Hagemeyer, [14]Mark A Febbraio, [15]Andrew L. Siebel, [16]Bronwyn A Kingwell [Full author list]Science Translational Medicine [curation]DOI: 10.1126/SCITRANSLMED.AAM6084
PubMed: 29021167		myocardial infarction [curation]2017-10-01
Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure[1]Francine Z Marques, [2]Priscilla R Prestes, [3]Sean G Byars, [4]Scott C Ritchie, [5]Peter Würtz, [6]Sheila K Patel, [7]Scott A Booth, [8]Indrajeetsinh Rana, [9]Yosuke Minoda, [10]Stuart P Berzins, ..., [29]Mary E Wlodek, [30]Paul A Lewandowski, [31]Lea M Delbridge, [32]Louise M Burrell, [33]Michael Inouye, ... [Full author list]Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease [curation]DOI: 10.1161/JAHA.117.005971
PubMed: 28615213		2017-06-14
Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency[1]Duncan E Crombie, [2]Claire L Curl, [3]Antonia Ja Raaijmakers, [4]Priyadharshini Sivakumaran, [5]Tejal Kulkarni, [6]Raymond Ching-Bong Wong, [7]Itsunari Minami, [8]Marguerite V Evans-Galea, [9]Shiang Y Lim, [10]Lea M Delbridge, [11]Louise A Corben, [12]Mirella Dottori, [13]Norio Nakatsuji, [14]Ian A Trounce, [15]Alex W. Hewitt, [16]Martin Delatycki, [17]Martin F Pera, [18]Alice Pébay [Full author list]Aging [curation]DOI: 10.18632/AGING.101247
PubMed: 28562313		Friedreich ataxia [curation]; electrophysiology [curation]2017-05-30
Myocardial stress and autophagy: mechanisms and potential therapies[1]Lea M Delbridge, [2]Kimberley M Mellor, [3]David J Taylor, [4]Roberta A Gottlieb [Full author list]Nature Reviews Cardiology [curation]DOI: 10.1038/NRCARDIO.2017.35
PubMed: 28361977		autophagy [curation]2017-03-31
A Small Cohort Omega-3 PUFA Supplement Study: Implications of Stratifying According to Lipid Membrane Incorporation in Cardiac Surgical Patients[1]Wendy T K Ip, [2]Chanchal Chandramouli, [3]Julian A Smith, [4]Peter L. McLennan, [5]Salvatore Pepe, [6]Lea M Delbridge [Full author list]Heart, Lung and Circulation [curation]DOI: 10.1016/J.HLC.2016.12.007
PubMed: 28237535		cardiac surgery [curation]2017-02-06
Diabetic Cardiomyopathy: The Case for a Role of Fructose in Disease Etiology[1]Lea M Delbridge, [2]Vicky L Benson, [3]Rebecca H Ritchie, [4]Kimberley M Mellor [Full author list]Diabetes [curation]DOI: 10.2337/DB16-0682
PubMed: 27879401		cardiomyopathy [curation]; diabetic cardiomyopathy [curation]2016-12-01
Transcriptomic effects of adenosine 2A receptor deletion in healthy and endotoxemic murine myocardium[1]Kevin Ashton, [2]Melissa E Reichelt, [3]S Jamal Mustafa, [4]Bunyen Teng, [5]Catherine Ledent, [6]Lea M Delbridge, [7]Polly A Hofmann, [8]R Ray Morrison, [9]John P Headrick [Full author list]Purinergic Signalling [curation]DOI: 10.1007/S11302-016-9536-1
PubMed: 27696085		transcriptome [curation]2016-09-30
Dietary omega-6 fatty acid replacement selectively impairs cardiac functional recovery after ischemia in female (but not male) rats[1]Wendy T K Ip, [2]Andrew McAlindon, [3]Sarah E Miller, [4]James R Bell, [5]Claire L Curl, [6]Catherine E Huggins, [7]Kimberley M. Mellor, [8]Antonia J A Raaijmakers, [9]Laura A Bienvenu, [10]Peter L. McLennan, [11]Salvatore Pepe, [12]Lea M Delbridge [Full author list]American Journal of Physiology Heart and Circulatory Physiology [curation]DOI: 10.1152/AJPHEART.00690.2015
PubMed: 27422989		fatty acid [curation]2016-07-15
Male and female hypertrophic rat cardiac myocyte functional responses to ischemic stress and β-adrenergic challenge are different[1]James R Bell, [2]Claire L Curl, [3]Tristan W Harding, [4]Martín Gerardo Vila Petroff, [5]Stephen B Harrap, [6]Lea M Delbridge [Full author list]Biology of Sex Differences [curation]DOI: 10.1186/S13293-016-0084-8
PubMed: 27390618		2016-07-07
Mitochondrial fission - a drug target for cytoprotection or cytodestruction?[1]Ayeshah A Rosdah, [2]Jessica K Holien, [3]Lea M Delbridge, [4]Gregory J Dusting, [5]Shiang Y Lim [Full author list]Pharmacology Research & Perspectives [curation]DOI: 10.1002/PRP2.235
PubMed: 27433345		mitochondrial fission [curation]2016-04-21
Tripartite motif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22.[1]Priscilla R Prestes, [2]Francine Z Marques, [3]Guillermo H López-Campos, [4]Scott A Booth, [5]Maree McGlynn, [6]Paul Lewandowski, [7]Lea M Delbridge, [8]Stephen B Harrap, [9]Fadi J. Charchar [Full author list]Journal of Hypertension [curation]DOI: 10.1097/HJH.0000000000000875
PubMed: 26886563		2016-02-17
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)[1]Daniel J. Klionsky, [2]Kotb Abdelmohsen, [3]Akihisa Abe, [4]Md Joynal Abedin, [5]Hagai Abeliovich, [6]Abraham Acevedo-Arozena, [7]Hiroaki Adachi, [8]Christopher M Adams, [9]Peter D Adams, [10]Khosrow Adeli, ..., [464]Dominic P Del Re, [465]Régis Delage-Mourroux, [466]Lea M Delbridge, [467]Louise Deldicque, [468]Elizabeth Delorme-Axford, ... [Full author list]Autophagy [curation]DOI: 10.1080/15548627.2015.1100356
PubMed: 26799652		cell biology [curation]; autophagy [curation]2016-01-02
Telomere dynamics during aging in polygenic left ventricular hypertrophy[1]Francine Z Marques, [2]Scott A Booth, [3]Priscilla R Prestes, [4]Claire L Curl, [5]Lea M Delbridge, [6]Paul Lewandowski, [7]Stephen B Harrap, [8]Fadi J. Charchar [Full author list]Physiological Genomics [curation]DOI: 10.1152/PHYSIOLGENOMICS.00083.2015
PubMed: 26508703		2015-10-27
CaMKIIδ and cardiomyocyte Ca(2+) signalling new perspectives on splice variant targeting[1]James R Bell, [2]Antonia J A Raaijmakers, [3]Johannes V Janssens, [4]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/1440-1681.12489
PubMed: 26361740		2015-09-12
The role of CaMKII in diabetic heart dysfunction[1]Lorna Daniels, [2]James R Bell, [3]Lea M Delbridge, [4]Fiona J McDonald, [5]Regis R Lamberts, [6]Jeffrey R Erickson [Full author list]Heart Failure Reviews [curation]DOI: 10.1007/S10741-015-9498-3
PubMed: 26198034		2015-09-01
Myocardial glycogen dynamics: new perspectives on disease mechanisms[1]Chanchal Chandramouli, [2]Upasna Varma, [3]Ellie M Stevens, [4]Rui-Ping Xiao, [5]David I Stapleton, [6]Kimberley M. Mellor, [7]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/1440-1681.12370
PubMed: 25676548		2015-04-01
Myocardial autophagic energy stress responses--macroautophagy, mitophagy, and glycophagy[1]Lea M Delbridge, [2]Kimberley M. Mellor, [3]David J R Taylor, [4]Roberta A Gottlieb [Full author list]American Journal of Physiology Heart and Circulatory Physiology [curation]DOI: 10.1152/AJPHEART.00002.2015
PubMed: 25747748		autophagy [curation]2015-03-06
Myocardial and cardiomyocyte stress resilience is enhanced in aromatase-deficient female mouse hearts through CaMKIIδ activation[1]James R Bell, [2]Gabriel B Bernasochi, [3]Amanda C Wollermann, [4]Antonia J A Raaijmakers, [5]Wah Chin Boon, [6]Evan R Simpson, [7]Claire L Curl, [8]Kimberley M. Mellor, [9]Lea M Delbridge [Full author list]Endocrinology [curation]DOI: 10.1210/EN.2014-1700
PubMed: 25625588		2015-01-27
Ca(2+) /calmodulin dependent kinase II: a critical mediator in determining reperfusion outcomes in the heart?[1]James R Bell, [2]Jeffrey R Erickson, [3]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/1440-1681.12301
PubMed: 25283076		2014-11-01
CaMKII-dependent responses to ischemia and reperfusion challenges in the heart[1]James R Bell, [2]Martin Vila-Petroff, [3]Lea M Delbridge [Full author list]Frontiers in Pharmacology [curation]DOI: 10.3389/FPHAR.2014.00096
PubMed: 24834054		2014-05-06
Glucose as an agent of post-translational modification in diabetes--New cardiac epigenetic insights[1]Kimberley M. Mellor, [2]Margaret Brimble, [3]Lea M Delbridge [Full author list]Life Sciences [curation]DOI: 10.1016/J.LFS.2014.03.020
PubMed: 24699006		2014-04-01
Aromatase transgenic upregulation modulates basal cardiac performance and the response to ischemic stress in male mice[1]James R Bell, [2]Gabriel B Bernasochi, [3]Upasna Varma, [4]Wah Chin Boon, [5]Stuart J Ellem, [6]Gail Petuna Risbridger, [7]Lea M Delbridge [Full author list]American Journal of Physiology Heart and Circulatory Physiology [curation]DOI: 10.1152/AJPHEART.00012.2014
PubMed: 24610919		2014-03-07
Ageing-related cardiomyocyte functional decline is sex and angiotensin II dependent[1]Kimberley M. Mellor, [2]Claire L Curl, [3]Chanchal Chandramouli, [4]Thierry Pedrazzini, [5]Igor R Wendt, [6]Lea M Delbridge [Full author list]Age [curation]DOI: 10.1007/S11357-014-9630-7
PubMed: 24566994		2014-02-25
Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition[1]Nicholas R Lim, [2]Colleen J Thomas, [3]Lokugan S Silva, [4]Yvonne Y Yeap, [5]Suwan Yap, [6]James R Bell, [7]Lea M Delbridge, [8]Marie A Bogoyevitch, [9]Owen L Woodman, [10]Spencer Williams, [11]Clive N May, [12]D C Ng [Full author list]Biochemical Journal [curation]DOI: 10.1042/BJ20121538
PubMed: 24032640		2013-12-01
Mineralocorticoid receptors and the heart, multiple cell types and multiple mechanisms: a focus on the cardiomyocyte[1]Laura A Bienvenu, [2]Melissa E Reichelt, [3]Lea M Delbridge, [4]Morag J. Young [Full author list]Clinical Science [curation]DOI: 10.1042/CS20130050
PubMed: 23829554		2013-11-01
Sex, sex steroids, and diabetic cardiomyopathy: making the case for experimental focus[1]Melissa E Reichelt, [2]Kimberley M Mellor, [3]James R Bell, [4]Chanchal Chandramouli, [5]John P Headrick, [6]Lea M Delbridge [Full author list]American Journal of Physiology Heart and Circulatory Physiology [curation]DOI: 10.1152/AJPHEART.00141.2013
PubMed: 23792676		cardiomyopathy [curation]; diabetic cardiomyopathy [curation]2013-06-21
Sex and sex hormones in cardiac stress--mechanistic insights[1]James R Bell, [2]Gabriel B Bernasochi, [3]Upasna Varma, [4]Antonia J A Raaijmakers, [5]Lea M Delbridge [Full author list]The Journal of Steroid Biochemistry and Molecular Biology [curation]DOI: 10.1016/J.JSBMB.2013.05.015
PubMed: 23770428		2013-06-13
Autophagic predisposition in the insulin resistant diabetic heart[1]Kimberley M Mellor, [2]Melissa E Reichelt, [3]Lea M Delbridge [Full author list]Life Sciences [curation]DOI: 10.1016/J.LFS.2012.03.042
PubMed: 22525376		autophagy [curation]; insulin resistance [curation]2012-04-13
Guidelines for the use and interpretation of assays for monitoring autophagy[1]Daniel J. Klionsky, ..., [2]Fábio Camargo Abdalla, [3]Hagai Abeliovich, [4]Robert T. Abraham, [5]Abraham Acevedo-Arozena, [6]Khosrow Adeli, [7]Lotta Agholme, [8]Maria Agnello, [9]Patrizia Agostinis, [10]Julio Aguirre-Ghiso, ..., [229]Alexei Degterev, [230]Benjamin Dehay, [231]Lea M Delbridge, [232]Francesca Demarchi, [233]Yi Zhen Deng, ... [Full author list]Autophagy [curation]DOI: 10.4161/AUTO.19496
PubMed: 22966490		autophagy [curation]; selective autophagy [curation]; process utilizing autophagic mechanism [curation]2012-04-01
The adenosine A₂A receptor - myocardial protectant and coronary target in endotoxemia[1]Melissa E Reichelt, [2]Kevin J Ashton, [3]Xing Lin Tan, [4]S Jamal Mustafa, [5]Catherine Ledent, [6]Lea M Delbridge, [7]Polly A Hofmann, [8]John P Headrick, [9]R Ray Morrison [Full author list]International Journal of Cardiology [curation]DOI: 10.1016/J.IJCARD.2011.11.075
PubMed: 22192288		2011-12-20
Aromatase deficiency confers paradoxical postischemic cardioprotection[1]James R Bell, [2]Kimberley M Mellor, [3]Amanda C Wollermann, [4]Wendy T K Ip, [5]Melissa E Reichelt, [6]Sarah J Meachem, [7]Evan R Simpson, [8]Lea M Delbridge [Full author list]Endocrinology [curation]DOI: 10.1210/EN.2011-1212
PubMed: 22028441		Aromatase deficiency [curation]2011-10-25
Cardiac ischaemic stress: cardiomyocyte Ca²⁺, sex and sex steroids[1]James R Bell, [2]Kimberley M. Mellor, [3]Amanda C Wollermann, [4]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/J.1440-1681.2011.05567.X
PubMed: 21722161		2011-10-01
Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro[1]Kimberley M. Mellor, [2]James R Bell, [3]Igor R Wendt, [4]Amy J Davidoff, [5]Rebecca H. Ritchie, [6]Lea M Delbridge [Full author list]PLOS One [curation]DOI: 10.1371/JOURNAL.PONE.0025204
PubMed: 21980397		2011-09-29
Evaluating RNA preparation options for archived myocardial biopsies[1]Wendy T K Ip, [2]Catherine Huggins, [3]Salvatore Pepe, [4]Lea M Delbridge [Full author list]Heart, Lung and Circulation [curation]DOI: 10.1016/J.HLC.2011.01.023
PubMed: 21342786		2011-02-20
Elevated dietary sugar and the heart: experimental models and myocardial remodeling[1]Kimberley M. Mellor, [2]Rebecca H. Ritchie, [3]Amy J Davidoff, [4]Lea M Delbridge [Full author list]Canadian Journal of Physiology and Pharmacology [curation]DOI: 10.1139/Y10-005
PubMed: 20555422		2010-05-01
Targeted GLUT-4 deficiency in the heart induces cardiomyocyte hypertrophy and impaired contractility linked with Ca(2+) and proton flux dysregulation[1]Andrea A Domenighetti, [2]Vennetia R Danes, [3]Claire L Curl, [4]Jennifer M Favaloro, [5]Joseph Proietto, [6]Lea M Delbridge [Full author list]Journal of Molecular and Cellular Cardiology [curation]DOI: 10.1016/J.YJMCC.2009.11.017
PubMed: 19962383		2009-12-03
High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy[1]Kimberley M. Mellor, [2]Rebecca H. Ritchie, [3]Greta Meredith, [4]Owen L Woodman, [5]Margaret J Morris, [6]Lea M Delbridge [Full author list]Nutrition [curation]DOI: 10.1016/J.NUT.2009.08.017
PubMed: 19932004		2009-11-20
Glucocorticoids suppress growth in neonatal cardiomyocytes co-expressing AT(2) and AT(1) angiotensin receptors[1]Enzo R Porrello, [2]William F Meeker, [3]Walter G Thomas, [4]Robert E Widdop, [5]Lea M Delbridge [Full author list]Neonatology [curation]DOI: 10.1159/000253757
PubMed: 19887855		2009-10-30
Reactive oxygen species and insulin-resistant cardiomyopathy[1]Kimberley M. Mellor, [2]Rebecca H. Ritchie, [3]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/J.1440-1681.2009.05274.X
PubMed: 19671065		reactive oxygen species [curation]; insulin resistance [curation]; preproinsulin [curation]2009-08-04
The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor[1]Enzo R Porrello, [2]Lea M Delbridge, [3]Walter G Thomas [Full author list]Frontiers in Bioscience [curation]DOI: 10.2741/3289
PubMed: 19273111		transmembrane protein [curation]2009-01-01
Early origins of cardiac hypertrophy: does cardiomyocyte attrition programme for pathological 'catch-up' growth of the heart?[1]Enzo R Porrello, [2]Robert E Widdop, [3]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/J.1440-1681.2008.05036.X
PubMed: 18759854		maternal health [curation]2008-08-26
Cardiac hypertrophy, substrate utilization and metabolic remodelling: cause or effect?[1]Rebecca H Ritchie, [2]Lea M Delbridge [Full author list]Clinical and Experimental Pharmacology and Physiology [curation]DOI: 10.1111/J.1440-1681.2006.04342.X
PubMed: 16445716		2006-01-01
Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure[1]Andrea A Domenighetti, [2]Qing Wang, [3]Marcel Egger, [4]Stephen M Richards, [5]Thierry Pedrazzini, [6]Lea M Delbridge [Full author list]Hypertension [curation]DOI: 10.1161/01.HYP.0000173069.53699.D9
PubMed: 15998712		2005-07-05
Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility[1]Petcharat Trongtorsak, [2]Trefor O Morgan, [3]Lea M Delbridge [Full author list]Journal of the Renin-Angiotensin-Aldosterone System [curation]DOI: 10.3317/JRAAS.2003.035
PubMed: 14689368		2003-12-01
Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice[1]Catherine Huggins, [2]Andrea A. Domenighetti, [3]Thierry Pedrazzini, [4]Salvatore Pepe, [5]Lea M. D. Delbridge, [5-Q96015961]Lea M Delbridge [Full author list]Journal of the Renin-Angiotensin-Aldosterone System [curation]DOI: 10.3317/JRAAS.2003.030
PubMed: 14608525		internal medicine [curation]; endocrinology [curation]2003-09-01
Endogenous cardiac opioids: enkephalins in adaptation and protection of the heart[1]Olivier W V van den Brink, [2]Lea M Delbridge, [3]Franklin L Rosenfeldt, [4]Daniel Penny, [5]Donald S Esmore, [6]Deahne Quick, [7]David M Kaye, [8]Salvatore Pepe [Full author list]Heart, Lung and Circulation [curation]DOI: 10.1046/J.1444-2892.2003.00240.X
PubMed: 16352129		enkephalin [curation]2003-01-01
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